Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 54112380
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54112380 F-box and leucine-rich repeat protein 10 isoform b
[Homo sapiens]
(1265 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [... 2614 0.0
gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [... 2544 0.0
gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens] 1116 0.0
gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi... 594 e-169
gi|32698700 PHD finger protein 8 [Homo sapiens] 291 3e-78
gi|90093355 jumonji C domain containing histone demethylase 1 ho... 274 3e-73
gi|117190342 PHD finger protein 2 [Homo sapiens] 248 3e-65
gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens] 78 6e-14
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens] 71 7e-12
gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens] 67 1e-10
gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens] 67 1e-10
gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens] 66 2e-10
gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens] 64 1e-09
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho... 62 3e-09
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 62 3e-09
gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens] 60 2e-08
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 59 3e-08
gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ... 59 4e-08
gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ... 59 4e-08
gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ... 57 9e-08
gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ... 57 9e-08
gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo ... 55 4e-07
gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Ho... 55 4e-07
gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo ... 55 4e-07
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 55 6e-07
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 54 7e-07
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 54 1e-06
gi|148746195 trichohyalin [Homo sapiens] 54 1e-06
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom... 52 5e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 51 6e-06
>gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [Homo
sapiens]
Length = 1265
Score = 2614 bits (6775), Expect = 0.0
Identities = 1265/1265 (100%), Positives = 1265/1265 (100%)
Query: 1 MEAEKDSGRRLRPIDRQRYDENEDLSDVEEIVSVRGFSLEEKLRSQLYQGDFVHAMEGKD 60
MEAEKDSGRRLRPIDRQRYDENEDLSDVEEIVSVRGFSLEEKLRSQLYQGDFVHAMEGKD
Sbjct: 1 MEAEKDSGRRLRPIDRQRYDENEDLSDVEEIVSVRGFSLEEKLRSQLYQGDFVHAMEGKD 60
Query: 61 FNYEYVQREALRVPLIFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKGTEM 120
FNYEYVQREALRVPLIFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKGTEM
Sbjct: 61 FNYEYVQREALRVPLIFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKGTEM 120
Query: 121 SMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQ 180
SMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQ
Sbjct: 121 SMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQ 180
Query: 181 TEATNAIAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNL 240
TEATNAIAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNL
Sbjct: 181 TEATNAIAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNL 240
Query: 241 ALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILH 300
ALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILH
Sbjct: 241 ALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILH 300
Query: 301 SFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYVLERYVYCVTQRSHLTQEYQRESMLI 360
SFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYVLERYVYCVTQRSHLTQEYQRESMLI
Sbjct: 301 SFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYVLERYVYCVTQRSHLTQEYQRESMLI 360
Query: 361 DAPRKPSIDGFSSDSWLEMEEEACDQQPQEEEEKDEEGEGRDRAPKPPTDGSTSPTSTPS 420
DAPRKPSIDGFSSDSWLEMEEEACDQQPQEEEEKDEEGEGRDRAPKPPTDGSTSPTSTPS
Sbjct: 361 DAPRKPSIDGFSSDSWLEMEEEACDQQPQEEEEKDEEGEGRDRAPKPPTDGSTSPTSTPS 420
Query: 421 EDQEALGKKPKAPALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTE 480
EDQEALGKKPKAPALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTE
Sbjct: 421 EDQEALGKKPKAPALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTE 480
Query: 481 FELKGLKALVEKLESLPENKKCVPEGIEDPQALLEGVKNVLKEHADDDPSLAITGVPVVT 540
FELKGLKALVEKLESLPENKKCVPEGIEDPQALLEGVKNVLKEHADDDPSLAITGVPVVT
Sbjct: 481 FELKGLKALVEKLESLPENKKCVPEGIEDPQALLEGVKNVLKEHADDDPSLAITGVPVVT 540
Query: 541 WPKKTPKNRAVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCK 600
WPKKTPKNRAVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCK
Sbjct: 541 WPKKTPKNRAVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCK 600
Query: 601 DMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSIC 660
DMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSIC
Sbjct: 601 DMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSIC 660
Query: 661 NEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQ 720
NEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQ
Sbjct: 661 NEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQ 720
Query: 721 KMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQE 780
KMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQE
Sbjct: 721 KMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQE 780
Query: 781 LSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDH 840
LSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDH
Sbjct: 781 LSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDH 840
Query: 841 SRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANEN 900
SRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANEN
Sbjct: 841 SRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANEN 900
Query: 901 QQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPS 960
QQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPS
Sbjct: 901 QQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPS 960
Query: 961 VSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVC 1020
VSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVC
Sbjct: 961 VSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVC 1020
Query: 1021 RTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLP 1080
RTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLP
Sbjct: 1021 RTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLP 1080
Query: 1081 GLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNR 1140
GLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNR
Sbjct: 1081 GLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNR 1140
Query: 1141 SKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDS 1200
SKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDS
Sbjct: 1141 SKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDS 1200
Query: 1201 LTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSSFQGRSCSTT 1260
LTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSSFQGRSCSTT
Sbjct: 1201 LTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSSFQGRSCSTT 1260
Query: 1261 RLGDE 1265
RLGDE
Sbjct: 1261 RLGDE 1265
>gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [Homo
sapiens]
Length = 1336
Score = 2544 bits (6593), Expect = 0.0
Identities = 1239/1277 (97%), Positives = 1239/1277 (97%), Gaps = 38/1277 (2%)
Query: 12 RPIDRQRYDENEDLSDVEEIVSVRGFSLEEKLRSQLYQGDFVHAMEGKDFNYEYVQREAL 71
RPIDRQRYDENEDLSDVEEIVSVRGFSLEEKLRSQLYQGDFVHAMEGKDFNYEYVQREAL
Sbjct: 43 RPIDRQRYDENEDLSDVEEIVSVRGFSLEEKLRSQLYQGDFVHAMEGKDFNYEYVQREAL 102
Query: 72 RVPLIFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYET 131
RVPLIFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYET
Sbjct: 103 RVPLIFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYET 162
Query: 132 PEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMK 191
PEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMK
Sbjct: 163 PEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMK 222
Query: 192 YPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGK 251
YPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGK
Sbjct: 223 YPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGK 282
Query: 252 QSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIY 311
QSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIY
Sbjct: 283 QSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIY 342
Query: 312 EIEDRTRVQPKFRYPFYYEMCWYVLERYVYCVTQRSHLTQEYQRESMLIDAPRKPSIDGF 371
EIEDRTRVQPKFRYPFYYEMCWYVLERYVYCVTQRSHLTQEYQRESMLIDAPRKPSIDGF
Sbjct: 343 EIEDRTRVQPKFRYPFYYEMCWYVLERYVYCVTQRSHLTQEYQRESMLIDAPRKPSIDGF 402
Query: 372 SSDSWLEMEEEACDQQPQEEEEKDEEGEGRDRAPKPPTDGSTSPTSTPSEDQEALGKKPK 431
SSDSWLEMEEEACDQQPQEEEEKDEEGEGRDRAPKPPTDGSTSPTSTPSEDQEALGKKPK
Sbjct: 403 SSDSWLEMEEEACDQQPQEEEEKDEEGEGRDRAPKPPTDGSTSPTSTPSEDQEALGKKPK 462
Query: 432 APALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVE 491
APALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVE
Sbjct: 463 APALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVE 522
Query: 492 KLESLPENKKCVPEGIEDPQALLEGVKNVLKEHADDDPSLAITGVPVVTWPKKTPKNRAV 551
KLESLPENKKCVPEGIEDPQALLEGVKNVLKEHADDDPSLAITGVPVVTWPKKTPKNRAV
Sbjct: 523 KLESLPENKKCVPEGIEDPQALLEGVKNVLKEHADDDPSLAITGVPVVTWPKKTPKNRAV 582
Query: 552 GRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRM 611
GRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRM
Sbjct: 583 GRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRM 642
Query: 612 KQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKI 671
KQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKI
Sbjct: 643 KQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKI 702
Query: 672 KESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQE 731
KESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQE
Sbjct: 703 KESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQE 762
Query: 732 PAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKR----- 786
PAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKR
Sbjct: 763 PAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRASSLQ 822
Query: 787 ---------------------------------LKPGKEDKLFRKKRRSWKNAEDRMALA 813
LKPGKEDKLFRKKRRSWKNAEDRMALA
Sbjct: 823 TSPGSSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPGKEDKLFRKKRRSWKNAEDRMALA 882
Query: 814 NKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLP 873
NKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLP
Sbjct: 883 NKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLP 942
Query: 874 NKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLN 933
NKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLN
Sbjct: 943 NKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLN 1002
Query: 934 GTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAA 993
GTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAA
Sbjct: 1003 GTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAA 1062
Query: 994 HVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGII 1053
HVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGII
Sbjct: 1063 HVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGII 1122
Query: 1054 RRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQW 1113
RRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQW
Sbjct: 1123 RRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQW 1182
Query: 1114 VEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSK 1173
VEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSK
Sbjct: 1183 VEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSK 1242
Query: 1174 LHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRY 1233
LHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRY
Sbjct: 1243 LHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRY 1302
Query: 1234 CKQVTKEGCEQFIAEMS 1250
CKQVTKEGCEQFIAEMS
Sbjct: 1303 CKQVTKEGCEQFIAEMS 1319
>gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]
Length = 1162
Score = 1116 bits (2886), Expect = 0.0
Identities = 631/1289 (48%), Positives = 803/1289 (62%), Gaps = 183/1289 (14%)
Query: 1 MEAEKDSGR---RLRPIDRQRYDENEDLSDVEEIVSVRGFSLEEKLRSQLYQGDFVHAME 57
ME E++ R RLR R+RY E++ +SD +EI R F LEEKL + Y +FV ME
Sbjct: 1 MEPEEERIRYSQRLRGTMRRRY-EDDGISD-DEIEGKRTFDLEEKLHTNKYNANFVTFME 58
Query: 58 GKDFNYEYVQREALRVPLIFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKG 117
GKDFN EY+QR LR PLIF+ DGLGIKMPDPDFTV DVK+ VGSRR+VDVMDVNTQKG
Sbjct: 59 GKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKG 118
Query: 118 TEMSMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLK 177
EM+M+Q+ RYYETPE +R+KLYNVISLEFSHT+LE++V+RP+ VD +DWVDNMWP+HLK
Sbjct: 119 IEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLK 178
Query: 178 EKQTEATNAIAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTL 237
E QTE+TNAI EM+YPKV+KYCLMSV+GC+TDFH+DFGGTSVWYH+ +GGK+FWLIPPT
Sbjct: 179 ESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTA 238
Query: 238 HNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGN 297
HNL LYE W+LSGKQ DIFLGDRV CQRIELKQGYTF IPSGWIHAVYTP D+LVFGGN
Sbjct: 239 HNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGN 298
Query: 298 ILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYVLERYVYCVTQRSHLTQEYQRES 357
LHSFN+PMQL+IY IEDRTRV KFRYPFYYEMCWYVLERYVYC+T RSHLT+E+Q+ES
Sbjct: 299 FLHSFNIPMQLKIYNIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKEFQKES 358
Query: 358 MLIDAPRKPSIDGFSSDSWLEMEEEACDQQPQEEEEKDEEGEGRDRAPKPPTDGSTSPTS 417
+ +D ++G S + +EEA D++P+ + R P +G
Sbjct: 359 LSMDL----ELNGLESGNG---DEEAVDREPRRLSSR------RSVLTSPVANGVNL--- 402
Query: 418 TPSEDQEALGKKPKAPALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTH 477
D + LGK ++ L LK+TL+ +S S P +P + + H
Sbjct: 403 ----DYDGLGKTCRS--LPSLKKTLAGDSSSDC-SRGSHNGQVWDPQCAPRKD---RQVH 452
Query: 478 LTEFELKGLKALVEKLESLPENKKCVPEGIEDPQALLEGVKNVLKEHADDDPSLAITGVP 537
LT FEL+GL+ LV+KLESLP +KKCVP GIED AL+ VK +L+E A+ DP LA+TGVP
Sbjct: 453 LTHFELEGLRCLVDKLESLPLHKKCVPTGIEDEDALIADVKILLEELANSDPKLALTGVP 512
Query: 538 VVTWPKKTPKNRAVGRPKGKLGPASAVK---------------LAANRTTAGARRRRTRC 582
+V WPK+ K + RPK ++ K AA+ +GARRRR RC
Sbjct: 513 IVQWPKRD-KLKFPTRPKVRVPTIPITKPHTMKPAPRLTPVRPAAASPIVSGARRRRVRC 571
Query: 583 RKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDT 642
RKC+AC++ ECG CH+C+DMKKFGGPGRMKQSC++RQC+AP LPH+
Sbjct: 572 RKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVT------------ 619
Query: 643 VEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKR 702
CS+C E+ E +L C C + H G Q
Sbjct: 620 --------------CSLCGEVDQ------NEETQDFEKKLMECCICNEIVHPGCL--QMD 657
Query: 703 GPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRR 762
G G LL E+ N C E P+ ++ S+K
Sbjct: 658 GEG----------LLNEELPN---------------CWECPKCYQEDSSEKA-------- 684
Query: 763 KSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQ 822
+K++ E +E K L+P + ++PL
Sbjct: 685 -------QKRKMEESDEEAVQAKVLRP--------------------LRSCDEPLTPPPH 717
Query: 823 EPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELS 882
P L SSP AGPS + +E+ K ++L R
Sbjct: 718 SPTSMLQLIHDPVSPRGMVTRSSPGAGPSDHHSASRDERFK----------RRQLLR--- 764
Query: 883 KELNHEIQRTENSLANENQQPIKSEPE-SEGEEPK-RPPGICERPHRFSKGLNGTPRELR 940
+Q TE ++ E + + E SE E+ K R + R +K L+GT +
Sbjct: 765 ------LQATERTMVREKENNPSGKKELSEVEKAKIRGSYLTVTLQRPTKELHGTSIVPK 818
Query: 941 HQL----GPSLRSPPRVISRPPPSVSPPKCIQM--------ERHVIRPPPISPPPDSLPL 988
Q +LR PRV+ + P+ +P + + E + + L
Sbjct: 819 LQAITASSANLRHSPRVLVQHCPARTPQRGDEEGLGGEEEEEEEEEEEDDSAEEGGAARL 878
Query: 989 D-------DGAAHVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHC 1041
+ DG M REVWM+VF YLS ++LC CMRVC+TW +WCCDKRLWT+IDL+ C
Sbjct: 879 NGRGSWAQDGDESWMQREVWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLWTKIDLSRC 938
Query: 1042 KSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSS 1101
K+I P LSGII+RQPVSLDLSWTNISKKQL+WL+NRLPGL+DL+L+GCSW AVSAL +S
Sbjct: 939 KAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTS 998
Query: 1102 SCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASL 1161
SCPLLRTLD++W G+KD Q+RDLL+PP D +PGQ DNRSKLRN+ + RLAGLDITDA+L
Sbjct: 999 SCPLLRTLDLRWAVGIKDPQIRDLLTPPAD-KPGQ-DNRSKLRNMTDFRLAGLDITDATL 1056
Query: 1162 RLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFK 1221
RLIIRHMPLLS+L LS+C+H+TDQS NLLTAVG++TR SLTE+N++ CNK+TDQ L + +
Sbjct: 1057 RLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLIYLR 1116
Query: 1222 RCGNICHIDLRYCKQVTKEGCEQFIAEMS 1250
R N+ IDLR CKQ+T++ CE FI+++S
Sbjct: 1117 RIANVTLIDLRGCKQITRKACEHFISDLS 1145
>gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapiens]
Length = 694
Score = 594 bits (1531), Expect = e-169
Identities = 318/710 (44%), Positives = 429/710 (60%), Gaps = 59/710 (8%)
Query: 555 KGKLGPASAVKLAANRTT----AGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGR 610
KG+ GP++ + + ++ AGARRRRTRCR+C AC+RTECG+CHFC+DMKKFGGPGR
Sbjct: 8 KGESGPSALLTPPMSSSSRGPGAGARRRRTRCRRCRACVRTECGDCHFCRDMKKFGGPGR 67
Query: 611 MKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLK 670
MKQSC++RQC APVLPHTAVCL+CGEAGKEDTVE EE KF L LMEC+ICNEI+HPGCLK
Sbjct: 68 MKQSCLLRQCTAPVLPHTAVCLLCGEAGKEDTVEGEEEKFGLSLMECTICNEIVHPGCLK 127
Query: 671 IKESEGVVNDELPNCWECPKCNHAGKTGKQK-RGPGFKYASNLP--GSLLKEQKMNRD-- 725
+ ++EGV+N E+PNCWECP+C G+T K GPG + A N SL K+ +
Sbjct: 128 MGKAEGVINAEIPNCWECPRCTQEGRTSKDSGEGPGRRRADNGEEGASLGSGWKLTEEPP 187
Query: 726 ------NKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQ 779
++G PA E P +R + + PP RKK K + +
Sbjct: 188 LPPPPPRRKGPLPAGPPPEDVPGPPKRKEREAGNEPPTP-----------RKKVKGGRER 236
Query: 780 ELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESD 839
L K G + L R L P + F P PP+ E
Sbjct: 237 HLK-----KVGGDACLLRGSDPGGPGLLPPRVL--NPSQAFSSCH----PGLPPENWEKP 285
Query: 840 HSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANE 899
P AEGP R K E K + ++R ++ ++
Sbjct: 286 K---------PPLASAEGPAVPSPSPQREKL---------ERFKRMCQLLERVPDTSSSS 327
Query: 900 NQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTP--RELRHQLGPSLRSPPRVISRP 957
+ S+ PG R ++G +G R R + P P ++S P
Sbjct: 328 SDSDSDSDSSGTSLSEDEAPGEARNGRRPARGSSGEKENRGGRRAVRPGSGGP--LLSWP 385
Query: 958 PPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCM 1017
PP+ Q+ERHV+RPPP SP PD+LPL G+ H + R W+ VF +L ++LC+CM
Sbjct: 386 LGPAPPPRPPQLERHVVRPPPRSPEPDTLPLAAGSDHPLPRAAWLRVFQHLGPRELCICM 445
Query: 1018 RVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLIN 1077
RVCRTW+RWC DKRLW R+DL+ KS+TP MLSG++RRQP +LDLSWT +SKKQL WL+N
Sbjct: 446 RVCRTWSRWCYDKRLWPRMDLSRRKSLTPPMLSGVVRRQPRALDLSWTGVSKKQLMWLLN 505
Query: 1078 RLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQM 1137
RL GL++LVLSGCSW++VSAL S+ P LR LD++W+E +KD+Q+R+LL PP D +PGQ
Sbjct: 506 RLQGLQELVLSGCSWLSVSALGSAPLPALRLLDLRWIEDVKDSQLRELLLPPPDTKPGQT 565
Query: 1138 DNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTT 1197
++R +L+ + ELRLAGL++TDASLRL++RH P LS L LS+C HV D S++LLTA +
Sbjct: 566 ESRGRLQGVAELRLAGLELTDASLRLLLRHAPQLSALDLSHCAHVGDPSVHLLTAPTSPL 625
Query: 1198 RDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIA 1247
R++L +NL+ C+++TD CL F+RC + +DLR C+Q++ E C + A
Sbjct: 626 RETLVHLNLAGCHRLTDHCLPLFRRCPRLRRLDLRSCRQLSPEACARLAA 675
>gi|32698700 PHD finger protein 8 [Homo sapiens]
Length = 1024
Score = 291 bits (745), Expect = 3e-78
Identities = 140/296 (47%), Positives = 194/296 (65%), Gaps = 16/296 (5%)
Query: 42 KLRSQLYQG--DFVHAMEGKDFNYEYVQREALRVPLIFREKDGLGIKMPDPDFTVRDVKL 99
+LRS+ + + + G E+++ + VP++ +KDGLG+ +P P FTVRDV+
Sbjct: 90 ELRSRTFDSSDEVILKPTGNQLTVEFLEENSFSVPILVLKKDGLGMTLPSPSFTVRDVEH 149
Query: 100 LVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKRP 159
VGS + +DV+DV Q +M + FV+YY + +R+K+ NVISLEFS T+L +LV+ P
Sbjct: 150 YVGSDKEIDVIDVTRQADCKMKLGDFVKYYYS--GKREKVLNVISLEFSDTRLSNLVETP 207
Query: 160 TVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTSV 219
+V + WV+N+WP+ + P V+KYCLMSV+ +TDFHIDFGGTSV
Sbjct: 208 KIVRKLSWVENLWPEE------------CVFERPNVQKYCLMSVRDSYTDFHIDFGGTSV 255
Query: 220 WYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIPS 279
WYHV +G KIF+LI PT NL L+E W S Q+++F GD+V++C + +KQG T FIP+
Sbjct: 256 WYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQNEMFFGDQVDKCYKCSVKQGQTLFIPT 315
Query: 280 GWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYV 335
GWIHAV TPVD L FGGN LHS N+ MQL+ YEIE R FR+P + +CWYV
Sbjct: 316 GWIHAVLTPVDCLAFGGNFLHSLNIEMQLKAYEIEKRLSTADLFRFPNFETICWYV 371
Score = 31.2 bits (69), Expect = 6.6
Identities = 14/52 (26%), Positives = 25/52 (48%), Gaps = 6/52 (11%)
Query: 654 LMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCN--HAGKTGKQKRG 703
++EC +C + H C+ ++E + D + CP C H K++RG
Sbjct: 20 MIECDMCQDWFHGSCVGVEEEKAADID----LYHCPNCEVLHGPSIMKKRRG 67
>gi|90093355 jumonji C domain containing histone demethylase 1
homolog D [Homo sapiens]
Length = 941
Score = 274 bits (701), Expect = 3e-73
Identities = 134/320 (41%), Positives = 198/320 (61%), Gaps = 17/320 (5%)
Query: 18 RYDENEDLSDVEEIVSVRGFSLEEKLRSQLYQG--DFVHAMEGKDFNYEYVQREALRVPL 75
R+D E + D + V + ++LRS+++ + + M G Y+++ VP+
Sbjct: 102 RHDYTE-IDDGSKPVQAGTRTFIKELRSRVFPSADEIIIKMHGSQLTQRYLEKHGFDVPI 160
Query: 76 IFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQ 135
+ + D LG+++P P F+V DV+ VG +++DV+DV Q ++M++ +V+Y+ P
Sbjct: 161 MVPKLDDLGLRLPSPTFSVMDVERYVGGDKVIDVIDVARQADSKMTLHNYVKYFMNPN-- 218
Query: 136 RDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKV 195
R K+ NVISLEFS TK+ LV+ P + + WV+N WP + P V
Sbjct: 219 RPKVLNVISLEFSDTKMSELVEVPDIAKKLSWVENYWPDD------------SVFPKPFV 266
Query: 196 KKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDI 255
+KYCLM V+ +TDFHIDFGGTSVWYHV G KIF+LI PT NLA YE W S QS++
Sbjct: 267 QKYCLMGVQDSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTDENLARYESWSSSVTQSEV 326
Query: 256 FLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIED 315
F GD+V++C + +KQG+T F+P+GWIHAV T D + FGGN LH+ N+ MQLR YE+E
Sbjct: 327 FFGDKVDKCYKCVVKQGHTLFVPTGWIHAVLTSQDCMAFGGNFLHNLNIGMQLRCYEMEK 386
Query: 316 RTRVQPKFRYPFYYEMCWYV 335
R + F++PF+ +CW+V
Sbjct: 387 RLKTPDLFKFPFFEAICWFV 406
Score = 32.3 bits (72), Expect = 2.9
Identities = 16/54 (29%), Positives = 25/54 (46%), Gaps = 6/54 (11%)
Query: 651 NLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCN--HAGKTGKQKR 702
N ++EC IC + H C+ ++E V D + CP C H K++R
Sbjct: 49 NRFMIECDICKDWFHGSCVGVEEHHAVDID----LYHCPNCAVLHGSSLMKKRR 98
>gi|117190342 PHD finger protein 2 [Homo sapiens]
Length = 1096
Score = 248 bits (632), Expect = 3e-65
Identities = 123/297 (41%), Positives = 175/297 (58%), Gaps = 16/297 (5%)
Query: 41 EKLRSQLYQG--DFVHAMEGKDFNYEYVQREALRVPLIFREKDGLGIKMPDPDFTVRDVK 98
++LRS+ + D V + G Y++ P++ +KDGLG+ +P P F V DV+
Sbjct: 91 KELRSRTFPSAEDVVARVPGSQLTLGYMEEHGFTEPILVPKKDGLGLAVPAPTFYVSDVE 150
Query: 99 LLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKR 158
VG R VDV DV QK +M + +FV YY + R ++ NV +LEFS T++ V+
Sbjct: 151 NYVGPERSVDVTDVTKQKDCKMKLKEFVDYYYS--TNRKRVLNVTNLEFSDTRMSSFVEP 208
Query: 159 PTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTS 218
P +V + WV+N WP A + PKV KYCL+ VK +TDFHID GG S
Sbjct: 209 PDIVKKLSWVENYWPDD------------ALLAKPKVTKYCLICVKDSYTDFHIDSGGAS 256
Query: 219 VWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIP 278
WYHV +G K F+LI P N++LYE W + S++F D+V++C + +KQG T FIP
Sbjct: 257 AWYHVLKGEKTFYLIRPASANISLYERWRSASNHSEMFFADQVDKCYKCIVKQGQTLFIP 316
Query: 279 SGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYV 335
SGWI+A TPVD L F G+ LHS +V MQ+R YE+E R ++ ++P + CWY+
Sbjct: 317 SGWIYATLTPVDCLAFAGHFLHSLSVEMQMRAYEVERRLKLGSLTQFPNFETACWYM 373
Score = 33.1 bits (74), Expect = 1.7
Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 11/59 (18%)
Query: 654 LMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKC--NHAGKTGKQKR-----GPG 705
++EC C + H C+ ++E E D + CP C H T K+KR GPG
Sbjct: 20 MIECDACKDWFHGSCVGVEEEEAPDID----IYHCPNCEKTHGKSTLKKKRTWHKHGPG 74
Score = 33.1 bits (74), Expect = 1.7
Identities = 36/137 (26%), Positives = 55/137 (40%), Gaps = 27/137 (19%)
Query: 861 KKKVKMRRKRRLPNKELSRELSKELNHEIQRTEN---SLANENQQPIKSEPESEGE-EPK 916
KK+ + LP +L K+L EI+ +EN ++ E S+ +G+ E +
Sbjct: 411 KKQALAEHEDELPEHFKPSQLIKDLAKEIRLSENASKAVRPEVNTVASSDEVCDGDREKE 470
Query: 917 RPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPS--VSPPKCIQMERHVI 974
PP E P+ L ++ S + P+ + P PS PPK
Sbjct: 471 EPPSPIEAT---------PPQSLLEKV--SKKKTPKTVKMPKPSKIPKPPK--------- 510
Query: 975 RPPPISPPPDSLPLDDG 991
PP PP +L L DG
Sbjct: 511 -PPKPPRPPKTLKLKDG 526
>gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]
Length = 436
Score = 77.8 bits (190), Expect = 6e-14
Identities = 75/269 (27%), Positives = 117/269 (43%), Gaps = 48/269 (17%)
Query: 1020 CRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPV--SLDLSWTN-ISKKQLSWLI 1076
C + +++C R +DL C SIT + L + P+ L++SW + ++K + L+
Sbjct: 135 CTSLSKFCSKLR---HLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALV 191
Query: 1077 NRLPGLRDLVLSGCSWIAVSAL--CSSSCPLLRTLDVQWVEGLKDAQMRDLL-------- 1126
GL+ L L GC+ + AL + CP L TL++Q + D + +
Sbjct: 192 RGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQS 251
Query: 1127 ------SPPTD---NRPGQMDNRSKL------------------RNIVELRLAGLD---- 1155
S TD N GQ R ++ RN EL L+
Sbjct: 252 LCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQ 311
Query: 1156 ITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQ 1215
ITD++L + H P L L LS+C +TD I L G D L I L +C +TD
Sbjct: 312 ITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHL-GNGACAHDQLEVIELDNCPLITDA 370
Query: 1216 CLSFFKRCGNICHIDLRYCKQVTKEGCEQ 1244
L K C ++ I+L C+Q+T+ G ++
Sbjct: 371 SLEHLKSCHSLERIELYDCQQITRAGIKR 399
Score = 65.9 bits (159), Expect = 2e-10
Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 45/249 (18%)
Query: 998 REVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDL-NHCKSITPLMLSGIIRRQ 1056
+E+ + +FS+L LC C +V R WN D W RIDL + + I ++
Sbjct: 30 KELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVE------ 83
Query: 1057 PVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSAL--CSSSCPLLRTLDVQWV 1114
NISK+ + LR L L GC + +AL + +C + L++
Sbjct: 84 ---------NISKRCGGF-------LRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGC 127
Query: 1115 EGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAG-LDITDASLRLIIRHMPLLSK 1173
DA L SKLR+ L LA IT+ SL+ + PLL +
Sbjct: 128 TKTTDATCTSL-----------SKFCSKLRH---LDLASCTSITNMSLKALSEGCPLLEQ 173
Query: 1174 LHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFF-KRCGNICHIDLR 1232
L++S+C+ VT I L L + L C ++ D+ L + C + ++L+
Sbjct: 174 LNISWCDQVTKDGIQAL----VRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQ 229
Query: 1233 YCKQVTKEG 1241
C Q+T EG
Sbjct: 230 TCLQITDEG 238
>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]
Length = 423
Score = 70.9 bits (172), Expect = 7e-12
Identities = 76/290 (26%), Positives = 119/290 (41%), Gaps = 52/290 (17%)
Query: 1008 LSHQDLCVCMRV----CRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIR--RQPVSLD 1061
+ H +L C ++ C + +R+C + +DL C SIT L GI R L+
Sbjct: 106 IEHLNLNGCTKITDSTCYSLSRFCSKLK---HLDLTSCVSITNSSLKGISEGCRNLEYLN 162
Query: 1062 LSWTN-ISKKQLSWLINRLPGLRDLVLSGCSWIAVSAL-----------------CSS-- 1101
LSW + I+K + L+ GL+ L+L GC+ + AL CS
Sbjct: 163 LSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRIT 222
Query: 1102 ---------SCPLLRTLDVQWVEGLKDAQMRDL---------LSPPTDNRPGQMDNRSKL 1143
C L+ L + L DA + L L +
Sbjct: 223 DEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLA 282
Query: 1144 RNIVELRLAGLD----ITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRD 1199
RN EL L+ ITD++L + H P L L LS+C +TD I L + T +
Sbjct: 283 RNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGI-LHLSNSTCGHE 341
Query: 1200 SLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEM 1249
L + L +C +TD L + C + ++L C+QVT+ G ++ A++
Sbjct: 342 RLRVLELDNCLLITDVALEHLENCRGLERLELYDCQQVTRAGIKRMRAQL 391
Score = 54.7 bits (130), Expect = 6e-07
Identities = 56/251 (22%), Positives = 102/251 (40%), Gaps = 29/251 (11%)
Query: 998 REVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDL-NHCKSITPLMLSGIIRR- 1055
+E+ + +FS+L LC C ++ + WN D W RIDL N + ++ I +R
Sbjct: 17 KELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQIDVEGRVVENISKRC 76
Query: 1056 ----QPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSS--CPLLRTL 1109
+ +SL + L + L L+GC+ I S S S C L+ L
Sbjct: 77 GGFLRKLSL-RGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHL 135
Query: 1110 DVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLD-ITDASLRLIIRHM 1168
D+ + ++ ++ + RN+ L L+ D IT + ++R
Sbjct: 136 DLTSCVSITNSSLKGI--------------SEGCRNLEYLNLSWCDQITKDGIEALVRGC 181
Query: 1169 PLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQ-CLSFFKRCGNIC 1227
L L L C + D+++ + L +NL C+++TD+ + + C +
Sbjct: 182 RGLKALLLRGCTQLEDEALKHI----QNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQ 237
Query: 1228 HIDLRYCKQVT 1238
+ L C +T
Sbjct: 238 ALCLSGCSNLT 248
Score = 31.2 bits (69), Expect = 6.6
Identities = 18/61 (29%), Positives = 31/61 (50%), Gaps = 4/61 (6%)
Query: 1201 LTEINLSDCNKVTDQCL-SFFKRCGNICHIDLRYCKQVTKEGC---EQFIAEMSSFQGRS 1256
L +++L C V D L +F + C NI H++L C ++T C +F +++ S
Sbjct: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTS 139
Query: 1257 C 1257
C
Sbjct: 140 C 140
>gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens]
Length = 660
Score = 67.0 bits (162), Expect = 1e-10
Identities = 27/46 (58%), Positives = 34/46 (73%), Gaps = 1/46 (2%)
Query: 576 RRRRTRCRKCEACLRTE-CGECHFCKDMKKFGGPGRMKQSCIMRQC 620
+R C +CEAC RTE CG C FC+DMKKFGGP +++Q C +RQC
Sbjct: 163 KRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQC 208
>gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]
Length = 656
Score = 67.0 bits (162), Expect = 1e-10
Identities = 27/46 (58%), Positives = 34/46 (73%), Gaps = 1/46 (2%)
Query: 576 RRRRTRCRKCEACLRTE-CGECHFCKDMKKFGGPGRMKQSCIMRQC 620
+R C +CEAC RTE CG C FC+DMKKFGGP +++Q C +RQC
Sbjct: 163 KRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQC 208
>gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]
Length = 491
Score = 66.2 bits (160), Expect = 2e-10
Identities = 85/328 (25%), Positives = 126/328 (38%), Gaps = 52/328 (15%)
Query: 953 VISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQD 1012
V S PP ++ P + R RP D LP H M + +FS+L
Sbjct: 88 VHSPPPTRLTHP----LIRLASRPQKEQASIDRLP-----DHSM-----VQIFSFLPTNQ 133
Query: 1013 LCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRR-----QPVSLDLSWTNI 1067
LC C RVCR W D RLW I L L + RR V L L +
Sbjct: 134 LCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVTV 193
Query: 1068 S------KKQLSWLINRLPGLRDLVLSGCSWIAVSALCS--SSCPLLRTLDVQWVEGLKD 1119
S + L + P LR L +SGC I+ A+ S CP L LDV +
Sbjct: 194 SGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTC 253
Query: 1120 AQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDA------SLRLIIRHMPLLSK 1173
+ S G+ ++ + LD+TD L I H L+
Sbjct: 254 ISLTREASIKLSPLHGK-----------QISIRYLDMTDCFVLEDEGLHTIAAHCTQLTH 302
Query: 1174 LHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCL-SFFKRCGNICHIDLR 1232
L+L C +TD+ + L S+ E+++SDC V+D L K + ++ +
Sbjct: 303 LYLRRCVRLTDEGLRYLVIYCA----SIKELSVSDCRFVSDFGLREIAKLESRLRYLSIA 358
Query: 1233 YCKQVTKEGCE---QFIAEMSSFQGRSC 1257
+C +VT G ++ +++ R C
Sbjct: 359 HCGRVTDVGIRYVAKYCSKLRYLNARGC 386
>gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]
Length = 418
Score = 63.5 bits (153), Expect = 1e-09
Identities = 68/272 (25%), Positives = 114/272 (41%), Gaps = 32/272 (11%)
Query: 999 EVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLN-HCKSITP-----LMLSGI 1052
E+ +F YL +D +VC W K +W ++ H + P L GI
Sbjct: 11 ELLAMIFGYLDVRDKGRAAQVCTAWRDAAYHKSVWRGVEAKLHLRRANPSLFPSLQARGI 70
Query: 1053 IRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQ 1112
R Q +SL ++ LS++I + + L LSGC + + L + VQ
Sbjct: 71 RRVQILSL--------RRSLSYVIQGMANIESLNLSGCYNLTDNGLGHAF--------VQ 114
Query: 1113 WVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGL-DITDASLRLIIRHMPLL 1171
+ L+ + L TD+ G++ L+ + L L G +IT+ L LI + L
Sbjct: 115 EIGSLRALNL-SLCKQITDSSLGRI--AQYLKGLEVLELGGCSNITNTGLLLIAWGLQRL 171
Query: 1172 SKLHLSYCNHVTDQSINLLTAVGTTTRD---SLTEINLSDCNKVTDQCLSFFKR-CGNIC 1227
L+L C H++D I L + + + L ++ L DC K+TD L R +
Sbjct: 172 KSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHISRGLTGLR 231
Query: 1228 HIDLRYCKQVTKEGCEQF--IAEMSSFQGRSC 1257
++L +C ++ G + + S RSC
Sbjct: 232 LLNLSFCGGISDAGLLHLSHMGSLRSLNLRSC 263
Score = 52.0 bits (123), Expect = 4e-06
Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 37/219 (16%)
Query: 1036 IDLNHCKSITPLMLSGIIRRQPVSLD--LSWTNISKKQLSWLINRLPGLRDLVLSGCSWI 1093
+ + H +T G + + ++L T++S K +S L GLR L LS C I
Sbjct: 185 VGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHIS---RGLTGLRLLNLSFCGGI 241
Query: 1094 AVSALCS-SSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLA 1152
+ + L S LR+L+++ + + D + L + LRL+
Sbjct: 242 SDAGLLHLSHMGSLRSLNLRSCDNISDTGIMHLA-------------------MGSLRLS 282
Query: 1153 GLDIT------DASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINL 1206
GLD++ D SL I + + L L L C H++D IN + L +N+
Sbjct: 283 GLDVSFCDKVGDQSLAYIAQGLDGLKSLSLCSC-HISDDGINRMVR----QMHGLRTLNI 337
Query: 1207 SDCNKVTDQCLSFF-KRCGNICHIDLRYCKQVTKEGCEQ 1244
C ++TD+ L + + IDL C ++TK G E+
Sbjct: 338 GQCVRITDKGLELIAEHLSQLTGIDLYGCTRITKRGLER 376
>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
sapiens]
Length = 1632
Score = 62.0 bits (149), Expect = 3e-09
Identities = 25/43 (58%), Positives = 30/43 (69%)
Query: 578 RRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQC 620
+R RC CE C + ECG+C CKDM KFGG GR KQ+C R+C
Sbjct: 665 KRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRC 707
Score = 36.6 bits (83), Expect = 0.16
Identities = 58/248 (23%), Positives = 94/248 (37%), Gaps = 62/248 (25%)
Query: 732 PAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLK--- 788
PAKR+ + EE+ R +SDE K+ K + EK + ++ R+R+
Sbjct: 191 PAKRKPQ-EESERAKSDESIKE----------------EDKDQDEKRRRVTSRERVARPL 233
Query: 789 PGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTA 848
P +E + + R+ K E+R K LR +EP PK + + +
Sbjct: 234 PAEEPERAKSGTRTEKE-EERDEKEEKRLRSQTKEP-------TPKQKLKEEPDREARAG 285
Query: 849 GPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEP 908
+ E +G E+ +K K R K+L+ + E E N Q +
Sbjct: 286 VQADEDEDGDEKDEK-----KHRSQPKDLAAKRRPE--------EKEPEKVNPQISDEKD 332
Query: 909 ESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQ 968
E E EE +R TP+E P+ + R + PPKCIQ
Sbjct: 333 EDEKEEKRR---------------KTTPKE------PTEKKMARAKTVMNSKTHPPKCIQ 371
Query: 969 MERHVIRP 976
+++ P
Sbjct: 372 CGQYLDDP 379
>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
sapiens]
Length = 1616
Score = 62.0 bits (149), Expect = 3e-09
Identities = 25/43 (58%), Positives = 30/43 (69%)
Query: 578 RRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQC 620
+R RC CE C + ECG+C CKDM KFGG GR KQ+C R+C
Sbjct: 649 KRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRC 691
Score = 36.6 bits (83), Expect = 0.16
Identities = 58/248 (23%), Positives = 94/248 (37%), Gaps = 62/248 (25%)
Query: 732 PAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLK--- 788
PAKR+ + EE+ R +SDE K+ K + EK + ++ R+R+
Sbjct: 175 PAKRKPQ-EESERAKSDESIKE----------------EDKDQDEKRRRVTSRERVARPL 217
Query: 789 PGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTA 848
P +E + + R+ K E+R K LR +EP PK + + +
Sbjct: 218 PAEEPERAKSGTRTEKE-EERDEKEEKRLRSQTKEP-------TPKQKLKEEPDREARAG 269
Query: 849 GPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEP 908
+ E +G E+ +K K R K+L+ + E E N Q +
Sbjct: 270 VQADEDEDGDEKDEK-----KHRSQPKDLAAKRRPE--------EKEPEKVNPQISDEKD 316
Query: 909 ESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQ 968
E E EE +R TP+E P+ + R + PPKCIQ
Sbjct: 317 EDEKEEKRR---------------KTTPKE------PTEKKMARAKTVMNSKTHPPKCIQ 355
Query: 969 MERHVIRP 976
+++ P
Sbjct: 356 CGQYLDDP 363
>gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]
Length = 479
Score = 59.7 bits (143), Expect = 2e-08
Identities = 84/384 (21%), Positives = 142/384 (36%), Gaps = 98/384 (25%)
Query: 950 PPRVISRPPPSVSPPKCIQMERHVIRPPPISP---PPDSLPLDDGAAH---VMHREVWMA 1003
PP + PPPS++ P + R + P +P P +L A ++
Sbjct: 49 PPPPPTLPPPSLAAP----LSRAALAGGPCTPAGGPASALAPGHPAERPPLATDEKILNG 104
Query: 1004 VFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRI--------------------------- 1036
+F Y S + CV +VC+ W R + W +
Sbjct: 105 LFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGEKEFVNLQGFA 164
Query: 1037 -------------DLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLR 1083
DL+ C+ I LS ++ ++ L + I+ L ++ ++ G+
Sbjct: 165 ARGFEGFCLVGVSDLDICEFIDNYALS---KKGVKAMSLKRSTITDAGLEVMLEQMQGVV 221
Query: 1084 DLVLSGCS-------WIAVSA----LCSSSC---------------PLLRTLDVQWV--- 1114
L LSGC+ W ++SA L S C P L L +Q
Sbjct: 222 RLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVT 281
Query: 1115 ----------EGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLD-ITDASLRL 1163
+G +R LLS G ++ L N+ L L+G +TD + L
Sbjct: 282 DTALAYFTARQGHSTHTLR-LLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVEL 340
Query: 1164 IIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRC 1223
+ ++ L L LS+C +TD ++ + L E+ L C ++TD LS+
Sbjct: 341 VAENLRKLRSLDLSWCPRITDMALEYVAC----DLHRLEELVLDRCVRITDTGLSYLSTM 396
Query: 1224 GNICHIDLRYCKQVTKEGCEQFIA 1247
++ + LR+C QV G + +A
Sbjct: 397 SSLRSLYLRWCCQVQDFGLKHLLA 420
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 58.9 bits (141), Expect = 3e-08
Identities = 80/306 (26%), Positives = 114/306 (37%), Gaps = 79/306 (25%)
Query: 717 LKEQKMNRD--NKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRK 774
+K+Q ++D +KE +E ++ + E +PRRR S+ P RR+S V +KR
Sbjct: 144 MKKQDEDKDKRDKEEKESSREKRERSRSPRRRK---SRSPSP----RRRSSPVRRERKRS 196
Query: 775 YEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPK 834
+ + R K RS A + K+E ELPE K
Sbjct: 197 HSRSPR---------------HRTKSRSPSPAPE------------KKEKTPELPEPSVK 229
Query: 835 TRESDHSRSSS-------PTAGPSTEGAE-GPE-----EKKKVKMRRKRRLPNKELSREL 881
+E ++S P P E E PE EK+K K R + R +K SR
Sbjct: 230 VKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTR 289
Query: 882 SKELNHEIQRTENSLANENQQPIKSEPESEGEEPKR--PPGICERPHRFSKGLNGTPREL 939
S+ +H R + + + P + P+R PP P R + + R
Sbjct: 290 SRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRR 349
Query: 940 RHQLGPS---------------------LRSPPRVISRPPPSVSPPKCIQMERHVIRP-P 977
R S SPPR R PS SPP+ RH RP P
Sbjct: 350 RSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPR----RRH--RPSP 403
Query: 978 PISPPP 983
P +PPP
Sbjct: 404 PATPPP 409
Score = 55.8 bits (133), Expect = 2e-07
Identities = 57/271 (21%), Positives = 98/271 (36%), Gaps = 33/271 (12%)
Query: 718 KEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEK 777
+E++ +R+ +E +RR +PRRRS ++ R++S R + K
Sbjct: 157 EEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRE-------RKRSHSRSPRHRTKSRS 209
Query: 778 PQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPE------- 830
P +K P + + K S + A + P EP++ PE
Sbjct: 210 PSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEK 269
Query: 831 ----APPKTRESDHSRSSSPTAGPS----------TEGAEGPEEKKKVKMR---RKRRLP 873
P++R SRS + + PS + P + + R R+R P
Sbjct: 270 EKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPP 329
Query: 874 NKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGL- 932
+ + ++R S A+ + S PK+PP P R ++ L
Sbjct: 330 RRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLS 389
Query: 933 -NGTPRELRHQLGPSLRSPPRVISRPPPSVS 962
+ +P RH+ P PP+ P P S
Sbjct: 390 PSASPPRRRHRPSPPATPPPKTRHSPTPQQS 420
Score = 45.4 bits (106), Expect = 3e-04
Identities = 65/291 (22%), Positives = 100/291 (34%), Gaps = 54/291 (18%)
Query: 726 NKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRK 785
+ E + P + + E RRR S+ P R+K R++R P R+
Sbjct: 501 SSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPT---RR 557
Query: 786 RLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPE-------APPKTRES 838
R P +RR R + P RR P P +PP R
Sbjct: 558 RRSPSPAPP---PRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKR-- 612
Query: 839 DHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLAN 898
R++SP P + P K++V P K+ S ++K + + +S
Sbjct: 613 ---RTASPPPPPKRRASPSPPPKRRVS----HSPPPKQRSSPVTKRRSPSL----SSKHR 661
Query: 899 ENQQPIKSEPESEGEEPK---------RPPGICERPHRFSKGLNGTPRELRHQLGPSLRS 949
+ P +S E+ +P R P P +G + +P+ R PS R
Sbjct: 662 KGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQR-RQSPSPSTR- 719
Query: 950 PPRVISRPP----------PSVSPPKCIQMERHV-------IRPPPISPPP 983
P R +SR P PS + + R V + PP P P
Sbjct: 720 PIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSP 770
Score = 37.4 bits (85), Expect = 0.092
Identities = 57/249 (22%), Positives = 92/249 (36%), Gaps = 45/249 (18%)
Query: 699 KQKRGPGFKYAS-NLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPD 757
KQ+ P K S +L K +R +E + P + +PR R+ + S PP
Sbjct: 642 KQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRH-SPSPRPRAPQTSSSPPP- 699
Query: 758 GLLRRKSDDVHLRKKRKYEKPQELSGRKRL-KPGKEDKLFRKKRRSWKNAEDRMALANKP 816
+RR + R++ + + R +P K K +S + +++ P
Sbjct: 700 --VRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSP 757
Query: 817 LRRFKQEPEDELPEAPPKTRESDH-----------SRSSSPTAGPST------EGAEGPE 859
EP + P APP +S ++ SPT PS EG +
Sbjct: 758 ------EPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKK 811
Query: 860 EKKKVKMRRKRRLPNKELSRELSKEL---------NHEIQRTENSLANENQQPI-----K 905
+KKK K +K + K + K + I +LA E +P+ K
Sbjct: 812 KKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQE--EPVAAPEPK 869
Query: 906 SEPESEGEE 914
E ESE E+
Sbjct: 870 KETESEAED 878
Score = 34.7 bits (78), Expect = 0.59
Identities = 35/136 (25%), Positives = 58/136 (42%), Gaps = 23/136 (16%)
Query: 377 LEMEEEACDQQPQEEEEKDEEGEGRDRAPKPPTDGSTSPTSTPSEDQEALGKKPKAPALR 436
++ ++E D++ +EE+E E R R+P+ S SP ++ +P R
Sbjct: 144 MKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSP------------RRRSSPVRR 191
Query: 437 FLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVEKLESL 496
KR+ S KS ++P SPA E K L E +K + V++ S
Sbjct: 192 ERKRSHSRSPRHRTKS--------RSP--SPAPEKKEKTPELPEPSVKVKEPSVQEATST 241
Query: 497 PENKKC-VPEGIEDPQ 511
+ K PE I +P+
Sbjct: 242 SDILKVPKPEPIPEPK 257
>gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 [Homo
sapiens]
Length = 690
Score = 58.5 bits (140), Expect = 4e-08
Identities = 63/251 (25%), Positives = 102/251 (40%), Gaps = 39/251 (15%)
Query: 1002 MAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLD 1061
+ +F YLS +D+ +C +V W LW ID + K++ P + VS
Sbjct: 164 LQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFSSVKNVIP-------DKYIVSTL 216
Query: 1062 LSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQ 1121
W RL LR L GC + S C L+ L+V D
Sbjct: 217 QRW-------------RLNVLR-LNFRGCLLRPKTFRSVSHCRNLQELNVSDCPTFTDES 262
Query: 1122 MRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNH 1181
MR + ++ PG ++ L L+ IT+ ++RL+ RH L L L+YC
Sbjct: 263 MRHI----SEGCPG----------VLCLNLSNTTITNRTMRLLPRHFHNLQNLSLAYCRR 308
Query: 1182 VTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFF-KRCGNICHIDLRYCKQVTKE 1240
TD+ + L +G L ++LS C +++ Q + C I H+ + +T +
Sbjct: 309 FTDKGLQYLN-LGNGCH-KLIYLDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLT-D 365
Query: 1241 GCEQFIAEMSS 1251
C + + E S
Sbjct: 366 NCVKALVEKCS 376
Score = 51.2 bits (121), Expect = 6e-06
Identities = 51/218 (23%), Positives = 96/218 (44%), Gaps = 38/218 (17%)
Query: 1085 LVLSGCSWIAVSAL--CSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPT-------DNRPG 1135
L LSGC+ I+V ++SC + L + + L D ++ L+ + P
Sbjct: 329 LDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPH 388
Query: 1136 QMDNRSKLRNIVELRLAGLD----ITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLT 1191
D + + +LR + +TDAS + I ++ P LS ++++ C +TD S+ L+
Sbjct: 389 ISDCTFRALSACKLRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLS 448
Query: 1192 AVGTTTRDSLT-----------------------EINLSDCNKVTD-QCLSFFKRCGNIC 1227
+ T +L E+NLS+C +++D + +RC N+
Sbjct: 449 PLKQLTVLNLANCVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNLN 508
Query: 1228 HIDLRYCKQVTKEGCEQFIAEMSSFQGRSCSTTRLGDE 1265
++ LR C+ +T +G +I + S S T + +E
Sbjct: 509 YLSLRNCEHLTAQGI-GYIVNIFSLVSIDLSGTDISNE 545
Score = 44.3 bits (103), Expect = 7e-04
Identities = 41/174 (23%), Positives = 84/174 (48%), Gaps = 22/174 (12%)
Query: 1082 LRDLVLSGCSWIAVSALC--SSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDN 1139
+R+L LS C ++ +++ S CP L L ++ E L T G + N
Sbjct: 481 IRELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHL------------TAQGIGYIVN 528
Query: 1140 RSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTA---VGTT 1196
+ ++V + L+G DI++ L ++ RH L +L +S C +TD I + + + +
Sbjct: 529 ---IFSLVSIDLSGTDISNEGLNVLSRHKK-LKELSVSECYRITDDGIQITDSAMEMLSA 584
Query: 1197 TRDSLTEINLSDCNKVTDQCLSFFK-RCGNICHIDLRYCKQVTKEGCEQFIAEM 1249
L +++S C +TDQ L + C + + ++YC ++K+ ++ +++
Sbjct: 585 KCHYLHILDISGCVLLTDQILEDLQIGCKQLRILKMQYCTNISKKAAQRMSSKV 638
>gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 [Homo
sapiens]
Length = 735
Score = 58.5 bits (140), Expect = 4e-08
Identities = 63/251 (25%), Positives = 102/251 (40%), Gaps = 39/251 (15%)
Query: 1002 MAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLD 1061
+ +F YLS +D+ +C +V W LW ID + K++ P + VS
Sbjct: 164 LQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFSSVKNVIP-------DKYIVSTL 216
Query: 1062 LSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQ 1121
W RL LR L GC + S C L+ L+V D
Sbjct: 217 QRW-------------RLNVLR-LNFRGCLLRPKTFRSVSHCRNLQELNVSDCPTFTDES 262
Query: 1122 MRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNH 1181
MR + ++ PG ++ L L+ IT+ ++RL+ RH L L L+YC
Sbjct: 263 MRHI----SEGCPG----------VLCLNLSNTTITNRTMRLLPRHFHNLQNLSLAYCRR 308
Query: 1182 VTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFF-KRCGNICHIDLRYCKQVTKE 1240
TD+ + L +G L ++LS C +++ Q + C I H+ + +T +
Sbjct: 309 FTDKGLQYLN-LGNGCH-KLIYLDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLT-D 365
Query: 1241 GCEQFIAEMSS 1251
C + + E S
Sbjct: 366 NCVKALVEKCS 376
Score = 51.2 bits (121), Expect = 6e-06
Identities = 51/218 (23%), Positives = 96/218 (44%), Gaps = 38/218 (17%)
Query: 1085 LVLSGCSWIAVSAL--CSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPT-------DNRPG 1135
L LSGC+ I+V ++SC + L + + L D ++ L+ + P
Sbjct: 329 LDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPH 388
Query: 1136 QMDNRSKLRNIVELRLAGLD----ITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLT 1191
D + + +LR + +TDAS + I ++ P LS ++++ C +TD S+ L+
Sbjct: 389 ISDCTFRALSACKLRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLS 448
Query: 1192 AVGTTTRDSLT-----------------------EINLSDCNKVTD-QCLSFFKRCGNIC 1227
+ T +L E+NLS+C +++D + +RC N+
Sbjct: 449 PLKQLTVLNLANCVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNLN 508
Query: 1228 HIDLRYCKQVTKEGCEQFIAEMSSFQGRSCSTTRLGDE 1265
++ LR C+ +T +G +I + S S T + +E
Sbjct: 509 YLSLRNCEHLTAQGI-GYIVNIFSLVSIDLSGTDISNE 545
Score = 40.4 bits (93), Expect = 0.011
Identities = 41/183 (22%), Positives = 83/183 (45%), Gaps = 24/183 (13%)
Query: 1082 LRDLVLSGCSWIAVSALC--SSSCPLLRTLDVQWVEGLKDAQMRDLLS---------PPT 1130
+R+L LS C ++ +++ S CP L L ++ E L + +++ T
Sbjct: 481 IRELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFSLVSIDLSGT 540
Query: 1131 DNRPGQMDNRSKLRNIVELRLAGL-DITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINL 1189
D ++ S+ + + EL ++ ITD ++ + +L L +SYC+ ++D I
Sbjct: 541 DISNEGLNVLSRHKKLKELSVSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKA 600
Query: 1190 LTAVGTTTRDSLTEINLSDCNKVTDQCLSFFK-RCGNICHIDLRYCKQVTKE-------G 1241
L +LT ++++ C K+TD + +C + +D+ C +T + G
Sbjct: 601 LAIYCI----NLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIG 656
Query: 1242 CEQ 1244
C+Q
Sbjct: 657 CKQ 659
>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
sapiens]
Length = 424
Score = 57.4 bits (137), Expect = 9e-08
Identities = 67/276 (24%), Positives = 117/276 (42%), Gaps = 51/276 (18%)
Query: 999 EVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITP-----LMLSGII 1053
E+ + +FS L +L VC+ W R D+ LW +DL K++ P L+ G+I
Sbjct: 103 ELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTG-KNLHPDVTGRLLSQGVI 161
Query: 1054 --------RRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPL 1105
QP++ S + LS + + L ++ S C
Sbjct: 162 AFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGIL--------------SQCSK 207
Query: 1106 LRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLD-ITDASLRLI 1164
L+ L +EGL+ LS P N +K N+V L L+G ++ +L+ +
Sbjct: 208 LQNLS---LEGLR-------LSDPIVN------TLAKNSNLVRLNLSGCSGFSEFALQTL 251
Query: 1165 IRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNK--VTDQCLSFFKR 1222
+ L +L+LS+C T++ + + A +++T++NLS K + +R
Sbjct: 252 LSSCSRLDELNLSWCFDFTEKHVQVAVA---HVSETITQLNLSGYRKNLQKSDLSTLVRR 308
Query: 1223 CGNICHIDLRYCKQVTKEGCEQFIAEMSSFQGRSCS 1258
C N+ H+DL + K C Q +++ Q S S
Sbjct: 309 CPNLVHLDLS-DSVMLKNDCFQEFFQLNYLQHLSLS 343
>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
sapiens]
Length = 410
Score = 57.4 bits (137), Expect = 9e-08
Identities = 67/276 (24%), Positives = 117/276 (42%), Gaps = 51/276 (18%)
Query: 999 EVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITP-----LMLSGII 1053
E+ + +FS L +L VC+ W R D+ LW +DL K++ P L+ G+I
Sbjct: 103 ELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTG-KNLHPDVTGRLLSQGVI 161
Query: 1054 --------RRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPL 1105
QP++ S + LS + + L ++ S C
Sbjct: 162 AFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGIL--------------SQCSK 207
Query: 1106 LRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLD-ITDASLRLI 1164
L+ L +EGL+ LS P N +K N+V L L+G ++ +L+ +
Sbjct: 208 LQNLS---LEGLR-------LSDPIVN------TLAKNSNLVRLNLSGCSGFSEFALQTL 251
Query: 1165 IRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNK--VTDQCLSFFKR 1222
+ L +L+LS+C T++ + + A +++T++NLS K + +R
Sbjct: 252 LSSCSRLDELNLSWCFDFTEKHVQVAVA---HVSETITQLNLSGYRKNLQKSDLSTLVRR 308
Query: 1223 CGNICHIDLRYCKQVTKEGCEQFIAEMSSFQGRSCS 1258
C N+ H+DL + K C Q +++ Q S S
Sbjct: 309 CPNLVHLDLS-DSVMLKNDCFQEFFQLNYLQHLSLS 343
>gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo
sapiens]
Length = 586
Score = 55.1 bits (131), Expect = 4e-07
Identities = 23/47 (48%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Query: 576 RRRRTRCRKCEACLRT-ECGECHFCKDMKKFGGPGRMKQSCIMRQCI 621
RR+ +C C ACLR +CG C FC D KFGG + +Q C RQC+
Sbjct: 309 RRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCL 355
>gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Homo
sapiens]
Length = 556
Score = 55.1 bits (131), Expect = 4e-07
Identities = 23/47 (48%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Query: 576 RRRRTRCRKCEACLRT-ECGECHFCKDMKKFGGPGRMKQSCIMRQCI 621
RR+ +C C ACLR +CG C FC D KFGG + +Q C RQC+
Sbjct: 283 RRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCL 329
>gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo
sapiens]
Length = 605
Score = 55.1 bits (131), Expect = 4e-07
Identities = 23/47 (48%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Query: 576 RRRRTRCRKCEACLRT-ECGECHFCKDMKKFGGPGRMKQSCIMRQCI 621
RR+ +C C ACLR +CG C FC D KFGG + +Q C RQC+
Sbjct: 332 RRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCL 378
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 54.7 bits (130), Expect = 6e-07
Identities = 23/48 (47%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 574 GARRRRTRCRKCEACLRTE-CGECHFCKDMKKFGGPGRMKQSCIMRQC 620
G + R RC C CLR + CG C C D KFGGP KQ C+ R+C
Sbjct: 958 GKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKC 1005
Score = 36.6 bits (83), Expect = 0.16
Identities = 27/115 (23%), Positives = 43/115 (37%), Gaps = 8/115 (6%)
Query: 867 RRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPH 926
+++++L ++E ++ +E + E + E E P + E++ P P P
Sbjct: 356 KQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPP 415
Query: 927 RFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISP 981
P P L PP PPP SPP E PPP+ P
Sbjct: 416 PLPPPSTSPP--------PPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVP 462
Score = 34.3 bits (77), Expect = 0.77
Identities = 76/362 (20%), Positives = 115/362 (31%), Gaps = 82/362 (22%)
Query: 692 NHAGKTGKQK-RGPGFKYASNLPGSLLKEQKMNRDN---KEGQEPAKRRSECEEAPRRRS 747
+ G+ G+ + RG G + S K+ KM + + + GQ + ++ P+RR
Sbjct: 286 SRGGRGGRGRGRGGGLPFVIKFV-SRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRV 344
Query: 748 DEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAE 807
P +K DD KK + EK +E G + KE++ ++ E
Sbjct: 345 GSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKE--GEE-----KEERAVAEEMMPAAEKE 397
Query: 808 DRMALANKPLRRFKQEPEDELPEA----------PPKTRESDHSRSSSPTAGPSTEGAEG 857
+ L PL P LP PP S S P E E
Sbjct: 398 EAK-LPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEES 456
Query: 858 PEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKR 917
P RKR P S+ +E + P + + G P+
Sbjct: 457 PPPVVPATCSRKRGRPPLTPSQRAERE-------AARAGPEGTSPPTPTPSTATGGPPED 509
Query: 918 PPGICERPHRFSKGLNG---------------TPREL---------RHQLGPSLRSP--- 950
P + + F K + TPR + ++ P LR P
Sbjct: 510 SPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITT 569
Query: 951 -PRVISRPPPSVSPPKC----------IQMERHVIR--------------PPPISPPPDS 985
P V P P SPP+ + R ++R PPP +PPP
Sbjct: 570 SPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPP 629
Query: 986 LP 987
P
Sbjct: 630 AP 631
Score = 32.3 bits (72), Expect = 2.9
Identities = 18/70 (25%), Positives = 29/70 (41%), Gaps = 12/70 (17%)
Query: 630 VCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECP 689
VCL+C G + L+ C +C + HP CL+ E + + C C
Sbjct: 1203 VCLLCASKGLHE------------LVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCK 1250
Query: 690 KCNHAGKTGK 699
C+ G+ G+
Sbjct: 1251 FCHVCGRKGR 1260
Score = 32.0 bits (71), Expect = 3.8
Identities = 35/150 (23%), Positives = 49/150 (32%), Gaps = 8/150 (5%)
Query: 815 KPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPN 874
K RRF DE P PPK S R T+ P + + +P
Sbjct: 541 KTPRRFM----DEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPL 596
Query: 875 KELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNG 934
E R + +E SL E P + P P P R +
Sbjct: 597 PEKRRSILREPTFRW----TSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQF 652
Query: 935 TPRELRHQLGPSLRSPPRVISRPPPSVSPP 964
TP E ++ S+ +PP + + P PP
Sbjct: 653 TPSEAHLKIYESVLTPPPLGAPEAPEPEPP 682
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 54.3 bits (129), Expect = 7e-07
Identities = 39/177 (22%), Positives = 77/177 (43%), Gaps = 18/177 (10%)
Query: 718 KEQKMNRDNKE---------GQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVH 768
KE+K R KE G+E ++R E E+ + R ++ +K + R +
Sbjct: 52 KERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGR 111
Query: 769 LRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDEL 828
+K+K E+ + K+ + K K +KKRR + E + ++ K+E ++
Sbjct: 112 RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKK 171
Query: 829 PEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKEL 885
E K R+ + R E E +E+KK + ++K R +++ R+ ++
Sbjct: 172 RERNRKERKKERERK---------ERRERKKERKKERRKKKERKKDRKTDRQTDSQV 219
Score = 49.7 bits (117), Expect = 2e-05
Identities = 51/199 (25%), Positives = 81/199 (40%), Gaps = 24/199 (12%)
Query: 720 QKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQ 779
Q+ + KE +E KR+ E E+ +R + KK RKKR+ K +
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKK---------------RKKRERGKER 75
Query: 780 ELSGRKRLKPGKEDK-LFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRES 838
E ++R K KE + R+KR+ K +R + ++ K+ E E + R+
Sbjct: 76 ERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR 135
Query: 839 DHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELS-KELNHEIQRTENSLA 897
R E G E+K R+KR+ +E RE + KE E +R E
Sbjct: 136 KKRRKKKRRKERKREKERGKRERK----RKKRKKEEREKKRERNRKERKKERERKER--- 188
Query: 898 NENQQPIKSEPESEGEEPK 916
E ++ K E + E K
Sbjct: 189 RERKKERKKERRKKKERKK 207
Score = 47.8 bits (112), Expect = 7e-05
Identities = 48/212 (22%), Positives = 88/212 (41%), Gaps = 17/212 (8%)
Query: 718 KEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEK 777
+E + ++ +E +E KR E E R E K+ + R+ K+RK +
Sbjct: 32 RESERKKERRE-REKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 778 PQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRE 837
+E RK+ K +E K ++ RR K ++R + R KQ E + + K R
Sbjct: 91 EKERRKRKKEKKKRERK--QRGRRERKKKKER----KERERENKQRRERKRKKRRKKKRR 144
Query: 838 SDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLA 897
+ R E G E+K+ K +++ R +E +R+ K+ +R E
Sbjct: 145 KERKR----------EKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
Query: 898 NENQQPIKSEPESEGEEPKRPPGICERPHRFS 929
+ ++ K E + + + ++ RP R S
Sbjct: 195 RKKERRKKKERKKDRKTDRQTDSQVFRPLRES 226
Score = 32.7 bits (73), Expect = 2.3
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 6/117 (5%)
Query: 696 KTGKQKRGPGFKYASNLPGSLLKEQK-MNRDNKEGQEPA--KRRSECEEAPRRRSDEHSK 752
K K+K+ K KE+K R+NK+ +E KRR + R+R E K
Sbjct: 96 KRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGK 155
Query: 753 KVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDR 809
+ R+K + R++ + E+ +E ++R + KE K R+K++ + +DR
Sbjct: 156 R-ERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK--ERKKDR 209
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 53.5 bits (127), Expect = 1e-06
Identities = 59/249 (23%), Positives = 103/249 (41%), Gaps = 21/249 (8%)
Query: 718 KEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEK 777
++++ R+ + +E + R E R R E ++ D R+ D+ ++RK E+
Sbjct: 389 RDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLER 448
Query: 778 P---QELSGRKRLKPG--KEDKLFRKKRRSWKNAEDR---MALANKPLRRFKQEPEDELP 829
+E + ++RLK +E K R+ + + E+R MA K L+ F ++ +D+
Sbjct: 449 KLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRD 508
Query: 830 EAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEI 889
+ PK + E E +++K ++ R+ L E + + E+
Sbjct: 509 D--PKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQ----RLLAEGHPDPDAEL 562
Query: 890 QRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRS 949
QR E Q IK EPESE EE E+ + K E + P L+
Sbjct: 563 QRMEQEAERRRQPQIKQEPESEEEEE-------EKQEKEEKREEPMEEEEEPEQKPCLKP 615
Query: 950 PPRVISRPP 958
R IS P
Sbjct: 616 TLRPISSAP 624
Score = 38.1 bits (87), Expect = 0.054
Identities = 52/227 (22%), Positives = 95/227 (41%), Gaps = 23/227 (10%)
Query: 707 KYASNLPGSLLKEQKMNRDNKEGQEPAKRRSEC-EEAPRRRSDEHSKKVPPDGLLRRKSD 765
K ASN G+ E N D + E KRR + + A E+S ++ +
Sbjct: 176 KKASN--GNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPS----QES 229
Query: 766 DVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKR-RSWKNAEDRMALANKPLRRF---- 820
D H RKK+K EK +++ R + P L K+ + + ED+ L ++ + +F
Sbjct: 230 DSHPRKKKK-EKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTH 288
Query: 821 --------KQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRL 872
K+E E + E + RE + R E EK+K + R + R
Sbjct: 289 KKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERD 348
Query: 873 PNKELSRELSKELNHEIQRTEN--SLANENQQPIKSEPESEGEEPKR 917
+++ ++E ++ + E R + ++ N+ +S +S E +R
Sbjct: 349 RDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERER 395
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 53.5 bits (127), Expect = 1e-06
Identities = 49/208 (23%), Positives = 97/208 (46%), Gaps = 13/208 (6%)
Query: 718 KEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEK 777
+++++ R +E QE +RR+E E+ + E +++ P + LRR+ + + LR+K + EK
Sbjct: 169 RDEELWRQRQEWQEREERRAEEEQLQSCKGHE-TEEFPDEEQLRRR-ELLELRRKGREEK 226
Query: 778 PQELSGRK-RLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDEL-----PEA 831
Q+ R+ R+ +E+K +RK+ + E+++ +R QE E++L E
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL 286
Query: 832 PPKTRESDHS-----RSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELN 886
+ +E + R E E EE+++ + RR+++ +E +E
Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEER 346
Query: 887 HEIQRTENSLANENQQPIKSEPESEGEE 914
E Q +Q ++ E E E E
Sbjct: 347 REQQLRREQEEERREQQLRREQEEERRE 374
Score = 50.1 bits (118), Expect = 1e-05
Identities = 52/246 (21%), Positives = 101/246 (41%), Gaps = 38/246 (15%)
Query: 718 KEQKMNRDNKE--GQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKY 775
+E+++ ++ ++ +EP KRR + E R+ +E + + LLR + + ++R+Y
Sbjct: 1142 EEEEVQQEEEQLLREEPEKRRRQ--ELERQYREEEELQQEEEQLLREEQEKRRQERERQY 1199
Query: 776 EKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPL------------------ 817
+ +EL +KR + +++ + W+ ++ NK
Sbjct: 1200 REEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLR 1259
Query: 818 -RRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKE 876
R+ +Q+ + L E + RE + R E EE+K+ K R ++ K+
Sbjct: 1260 DRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQ 1319
Query: 877 LSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTP 936
L RE +R E E + + E + E ++P ER +F +
Sbjct: 1320 LLRE---------EREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE------ 1364
Query: 937 RELRHQ 942
ELRHQ
Sbjct: 1365 EELRHQ 1370
Score = 49.3 bits (116), Expect = 2e-05
Identities = 41/203 (20%), Positives = 91/203 (44%), Gaps = 15/203 (7%)
Query: 718 KEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEK 777
+++K + ++ + + R +E + R E +K + LR++++ LR++ +Y K
Sbjct: 1689 RDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRK 1748
Query: 778 PQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRE 837
E ++L+P +E++ R++ R DR + LR+ ++E + E+ K RE
Sbjct: 1749 ILE---EEQLRPEREEQQLRRQER------DRKFREEEQLRQEREEQQLRSQESDRKFRE 1799
Query: 838 SDHSRS--SSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKE----LNHEIQR 891
+ R P + E++++++ + + +E R+ E + +R
Sbjct: 1800 EEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRR 1859
Query: 892 TENSLANENQQPIKSEPESEGEE 914
E L E +Q + E E + E
Sbjct: 1860 EEQELWQEEEQKRRQERERKLRE 1882
Score = 48.5 bits (114), Expect = 4e-05
Identities = 47/219 (21%), Positives = 96/219 (43%), Gaps = 21/219 (9%)
Query: 718 KEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSD---DVHLRKKRK 774
+EQ++ R+ +E + + R E EE R + +++ + LRR+ + LR++++
Sbjct: 347 REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 406
Query: 775 YEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPK 834
+ Q+L ++L+ +E +L R++ + + L+R ++E D L
Sbjct: 407 LRREQQLRREQQLR--REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEET 464
Query: 835 TRESDHSRSSSPTAGPSTEGAEG-----PEEKKKVKMRRKRRLPNKE-------LSRELS 882
R R E E EE+++ + RR+++L ++ L R+
Sbjct: 465 ERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEE 524
Query: 883 KELNHEIQRTENSLANE----NQQPIKSEPESEGEEPKR 917
+E + R+E L E +Q +K E E E+ +R
Sbjct: 525 EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR 563
Score = 47.4 bits (111), Expect = 9e-05
Identities = 59/246 (23%), Positives = 102/246 (41%), Gaps = 48/246 (19%)
Query: 718 KEQKMNRDNKE--GQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRK-KRK 774
K++K+ + ++ G+EP KRR + E R +E ++ + LLR + + ++ +R+
Sbjct: 962 KDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQE--EEQLLREEREKRRRQEWERQ 1019
Query: 775 YEKPQELSGRKR--LKPGKEDKLFRKKRRSWKN------------AEDRMALANKPLRR- 819
Y K EL + L+ +E + +++ R ++ E+R + L R
Sbjct: 1020 YRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQ 1079
Query: 820 ------FKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLP 873
+QE E L E P K R + R E + EE+ + R KRR
Sbjct: 1080 YRKEEELQQEEEQLLREEPEKRRRQERERQCR-----EEEELQQEEEQLLREEREKRR-- 1132
Query: 874 NKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLN 933
+EL R+ R E + E +Q ++ EPE KR ER +R + L
Sbjct: 1133 RQELERQ---------YREEEEVQQEEEQLLREEPE------KRRRQELERQYREEEELQ 1177
Query: 934 GTPREL 939
+L
Sbjct: 1178 QEEEQL 1183
Score = 47.0 bits (110), Expect = 1e-04
Identities = 53/228 (23%), Positives = 94/228 (41%), Gaps = 39/228 (17%)
Query: 712 LPGSLLKEQKMNRDNKEG---QEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVH 768
L L KEQ++ ++ +E +E KRR + +E R+ +E + + LLR + +
Sbjct: 895 LQEQLRKEQQLLQEEEEELQREEREKRRRQEQE--RQYREEEQLQQEEEQLLREEREKRR 952
Query: 769 LRKK-RKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDE 827
+++ R+Y K ++L ++ G+E + R++ R K E+ +QE E
Sbjct: 953 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE---------EELQQEEEQL 1003
Query: 828 LPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNH 887
L E K R + R + + EE+ + R KRRL +E +EL
Sbjct: 1004 LREEREKRRRQEWERQYR-----KKDELQQEEEQLLREEREKRRLQERERQYREEEELQQ 1058
Query: 888 EIQ-------------------RTENSLANENQQPIKSEPESEGEEPK 916
E + R E L E +Q ++ EPE + +
Sbjct: 1059 EEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER 1106
Score = 46.6 bits (109), Expect = 2e-04
Identities = 47/213 (22%), Positives = 93/213 (43%), Gaps = 16/213 (7%)
Query: 718 KEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYE- 776
++Q+ R ++ QE ++ E R+ +E ++ P + ++ LRK + E
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL 286
Query: 777 ---KPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPP 833
+ +E ++RL+ +E +L RK+ + ++ + + ++ E +L
Sbjct: 287 RRERQEEEQQQQRLR--REQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQE 344
Query: 834 KTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRL-PNKELSRE----LSKELNHE 888
+ RE R E EE+++ ++RR+++L ++L RE ++L E
Sbjct: 345 ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRRE 404
Query: 889 IQ-RTENSLANENQ----QPIKSEPESEGEEPK 916
Q R E L E Q Q ++ E E E E K
Sbjct: 405 QQLRREQQLRREQQLRREQQLRREQEEERHEQK 437
Score = 45.4 bits (106), Expect = 3e-04
Identities = 54/236 (22%), Positives = 95/236 (40%), Gaps = 20/236 (8%)
Query: 718 KEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEK 777
+E+++ + K E +R E E + ++ E K P + +S+ R+ + Y +
Sbjct: 664 EEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESE-ADARQSKVYSR 722
Query: 778 PQELSGRKRLKPGKEDKLFRKKRRSWKNAE--DRMALANKPLRRF--------KQEPEDE 827
P++ G++R + +E + R+ W+ E R + R F K E +
Sbjct: 723 PRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQ 782
Query: 828 LPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNH 887
A P RE R E PEE++K + RR+RR KEL E
Sbjct: 783 RLSARPPLREQ-RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQ---FLEEEE 838
Query: 888 EIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQL 943
++QR E + QQ + E + ++ +R R ++ L + RH L
Sbjct: 839 QLQRRERA-----QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTL 889
Score = 42.7 bits (99), Expect = 0.002
Identities = 39/187 (20%), Positives = 90/187 (48%), Gaps = 16/187 (8%)
Query: 716 LLKEQKMNRDNKEGQ--EPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKK- 772
L +EQ++ R E + E + R E E+ RR + + +K+ + LR + ++ LR++
Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERY-RKILEEEQLRPEREEQQLRRQE 1768
Query: 773 --RKYEKPQELSGRK---RLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPED- 826
RK+ + ++L + +L+ + D+ FR++ + + E++ + +++ E E
Sbjct: 1769 RDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQL 1828
Query: 827 ELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPE------EKKKVKMRRKRRLPNKELSRE 880
+L E + R+ + + + E + E E++K + R+R+L + + R+
Sbjct: 1829 QLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQ 1888
Query: 881 LSKELNH 887
+E H
Sbjct: 1889 QKEEQRH 1895
Score = 42.0 bits (97), Expect = 0.004
Identities = 51/219 (23%), Positives = 99/219 (45%), Gaps = 33/219 (15%)
Query: 716 LLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSD---DVHLRKK 772
L +EQ++ R +E +RR + EE ++ ++ + LRR+ + + LR++
Sbjct: 300 LRREQQLRRKQEE-----ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRRE 354
Query: 773 RKYEKPQELSGRKRLKPGKEDKLFRKK--RRSWKNAEDRMALANKPLRRFKQ-EPEDELP 829
++ E+ ++ R++ + +E +L R++ RR + ++ + LRR +Q E +L
Sbjct: 355 QEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 414
Query: 830 EAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKE------LSRELSK 883
RE R E E E+K + RR++RL ++ L RE
Sbjct: 415 REQQLRREQQLRR----------EQEEERHEQKHEQERREQRLKREQEERRDWLKREEET 464
Query: 884 ELNHEIQRTENSLANENQQP-----IKSEPESEGEEPKR 917
E HE +R + L + ++ +K E E E+ +R
Sbjct: 465 E-RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQER 502
Score = 41.6 bits (96), Expect = 0.005
Identities = 55/268 (20%), Positives = 109/268 (40%), Gaps = 14/268 (5%)
Query: 690 KCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDE 749
+C + +Q R F+ +++K + ++ + + R EE + R +
Sbjct: 1400 RCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQER 1459
Query: 750 HSKKVPPDGLLR-RKSDDVHLRKK-RKY-EKPQELSGRKRLKPGKEDKLFRKKRRSWKNA 806
H K + LL+ R+ +H +++ RK+ E+ Q+L ++R + +E +L ++
Sbjct: 1460 HRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLE 1519
Query: 807 EDRMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKM 866
E++ + R+F QE + + + R D R E E ++ + +
Sbjct: 1520 EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE--QQLSRQER 1577
Query: 867 RRKRRLPNKELSRELSKELNHEIQRTENSL-ANENQQPIKSEPESEGEE-----PKRPPG 920
RK RL +++ R+ E + E L E QQ ++ E + + E +R
Sbjct: 1578 DRKFRLEEQKVRRQ---EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQ 1634
Query: 921 ICERPHRFSKGLNGTPRELRHQLGPSLR 948
R R K L P+ R + LR
Sbjct: 1635 QLHRQERDRKFLEEEPQLRRQEREQQLR 1662
Score = 41.2 bits (95), Expect = 0.006
Identities = 45/209 (21%), Positives = 88/209 (42%), Gaps = 29/209 (13%)
Query: 716 LLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKY 775
L +EQ++ R+ +E + K E E +R E + D L R + + H +++RK
Sbjct: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERR----DWLKREEETERHEQERRKQ 474
Query: 776 E--KPQELSGRKR-LKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPED----EL 828
+ + QE R+R LK +E++ +++RR ++ ++E E+ L
Sbjct: 475 QLKRDQEEERRERWLKLEEEERREQQERRE---------------QQLRREQEERREQRL 519
Query: 829 PEAPPKTRESDHSRSSSPTAGPSTEGAE---GPEEKKKVKMRRKRRLPNKELSRELSKEL 885
+ R RS E E EE+K+++ R+ + +E + L
Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL 579
Query: 886 NHEIQRTENSLANENQQPIKSEPESEGEE 914
E +R + L E ++ ++ + E E
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVE 608
Score = 40.8 bits (94), Expect = 0.008
Identities = 46/209 (22%), Positives = 88/209 (42%), Gaps = 23/209 (11%)
Query: 715 SLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRK 774
SLL++++ D + EP R+ E E RRR R++ + + +
Sbjct: 108 SLLQDRRQEEDQRRF-EPRDRQLEEEPGQRRRQK------------RQEQERELAEGEEQ 154
Query: 775 YEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPK 834
EK + L R R + ++++L+R+ R+ W+ E+R A + L+ K +E P+
Sbjct: 155 SEKQERLEQRDRQR--RDEELWRQ-RQEWQEREERRA-EEEQLQSCKGHETEEFPDEEQL 210
Query: 835 TRES-----DHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELS-RELSKELNHE 888
R R + EE++K +R+ L +E +E + E
Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE 270
Query: 889 IQRTENSLANENQQPIKSEPESEGEEPKR 917
+Q E L +Q ++ E + E ++ +R
Sbjct: 271 LQEEEEQLRKLERQELRRERQEEEQQQQR 299
Score = 39.7 bits (91), Expect = 0.018
Identities = 53/244 (21%), Positives = 102/244 (41%), Gaps = 51/244 (20%)
Query: 716 LLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPP---DGLLRRKSDDVHLRKK 772
L EQ++ R+ +E +E +R E + + R ++ K+ D LL+R+ + R++
Sbjct: 532 LRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEE----RRQ 587
Query: 773 RKYEKPQELSGRKRLKPGKEDKLFRKKRRSWK---------------NAEDRMALANKPL 817
++ ++ QE +RLK + ++L +++RR + +E++ + L
Sbjct: 588 QRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQL 647
Query: 818 RR---------FKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRR 868
RR K+E E+E E K RE + R A EE+++ + R
Sbjct: 648 RREQQERREQRLKREEEEERLEQRLK-REHEEERREQELA---------EEEQEQARERI 697
Query: 869 KRRLPNKELSRELSKELNH-----EIQRTENSLANENQQPIKSEPESEGEEPKRPPGICE 923
K R+P + E + ++ E + Q+ + ESE + + E
Sbjct: 698 KSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEE-----E 752
Query: 924 RPHR 927
R HR
Sbjct: 753 RAHR 756
Score = 39.3 bits (90), Expect = 0.024
Identities = 51/246 (20%), Positives = 103/246 (41%), Gaps = 27/246 (10%)
Query: 686 WECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKE--GQEPAKRRSECEEAP 743
WE K N +G + L S L++++ +D + G++ + R E
Sbjct: 1227 WEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDR----EQE 1282
Query: 744 RRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSW 803
RRR + + P + L R+ R+ RK ++ ++L +R + + + RK R
Sbjct: 1283 RRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEE 1342
Query: 804 KNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKK 863
+ ++R +PLRR QE + + E + +E +G + EE+++
Sbjct: 1343 QLLQER---EEQPLRR--QERDRKFREEELRHQE---------------QGRKFLEEEQR 1382
Query: 864 VKMRRKRRLPNKELSRELSKELNHEI-QRTENSLANENQQPIKSEPESEGEEPKRPPGIC 922
++ + + R KE + +E ++ Q + E QQ + E + + E ++
Sbjct: 1383 LRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ 1442
Query: 923 ERPHRF 928
ER +F
Sbjct: 1443 ERERKF 1448
Score = 37.4 bits (85), Expect = 0.092
Identities = 44/212 (20%), Positives = 89/212 (41%), Gaps = 12/212 (5%)
Query: 718 KEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLR--KKRKY 775
++ + RD K +E + E EE R + K + + LRR+ + LR + RK+
Sbjct: 1611 QQLRQERDRKF-REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKF 1669
Query: 776 EKPQEL---SGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAP 832
+ ++L ++L+ + D+ FR++ + + E + + +QE E + E
Sbjct: 1670 REEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEE 1729
Query: 833 PKTRESDHS--RSSSPTAGPSTEGAEGP--EEKKKVKMRRKRRLPNKELSRELSKELNHE 888
+E++ R E P EE++ + R R+ +E R+ +E
Sbjct: 1730 QLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLR 1789
Query: 889 IQRTENSLANENQQPIKSEPESEGEEPKRPPG 920
Q ++ E Q ++ E E + P++ G
Sbjct: 1790 SQESDRKFREEEQ--LRQEREEQQLRPQQRDG 1819
Score = 34.7 bits (78), Expect = 0.59
Identities = 43/225 (19%), Positives = 90/225 (40%), Gaps = 18/225 (8%)
Query: 718 KEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEK 777
+EQ + ++ +R + E R ++ K + + LRR+ + RK K E+
Sbjct: 1341 EEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERE---RKFLKEEQ 1397
Query: 778 PQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRE 837
R++ D+ FR++ + E + + +QE E + E + R+
Sbjct: 1398 QLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQ 1457
Query: 838 SDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLA 897
H + EE++ ++ R +++L +E R+ +E +++R E
Sbjct: 1458 ERHRKFR--------------EEEQLLQEREEQQLHRQERDRKFLEE-EQQLRRQERDRK 1502
Query: 898 NENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQ 942
Q+ EPE + E ++ +R +F + R+ R Q
Sbjct: 1503 FREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQ 1547
>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform c [Homo sapiens]
Length = 1462
Score = 51.6 bits (122), Expect = 5e-06
Identities = 66/314 (21%), Positives = 114/314 (36%), Gaps = 40/314 (12%)
Query: 634 CGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKI----KESEGVVNDELPNCWECP 689
CG+ D + E G+ M+ S E+I G ++ K +G V + P+
Sbjct: 1161 CGKMRIGDEILEINGE-TTKNMKHSRAIELIKNGGRRVRLFLKRGDGSVPEYDPS----- 1214
Query: 690 KCNHAGKTGKQ-----KRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPR 744
H TG Q + GP + +L S + + + E + A+ E R
Sbjct: 1215 SDRHGPATGPQGVPEVRAGPDRRQHPSLESSYPPDLHKSSPHGEKRAHARDPKGSREYSR 1274
Query: 745 RRSDEHS----KKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKR 800
+ ++ H+ + P G R K R+ + E+ +G KR P K+R
Sbjct: 1275 QPNEHHTWNGTSRKPDSGACRPKDRAPEGRRDAQAERAAAANGPKRRSP-------EKRR 1327
Query: 801 RSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSS-------SPTAGPSTE 853
++A++ + K +R PE +P + R+ SR P
Sbjct: 1328 EGTRSADNTLERREKHEKRRDVSPERRRERSPTRRRDGSPSRRRRSLERLLEQRRSPERR 1387
Query: 854 GAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGE 913
PE + K RR+ R P + R L K R A+ ++ + + G
Sbjct: 1388 RGGSPERRAKSTDRRRARSPERRRERSLDK-------RNREDRASHREREEANLKQDAGR 1440
Query: 914 EPKRPPGICERPHR 927
+ PP RP++
Sbjct: 1441 SSRHPPEQRRRPYK 1454
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 51.2 bits (121), Expect = 6e-06
Identities = 53/239 (22%), Positives = 98/239 (41%), Gaps = 19/239 (7%)
Query: 691 CNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEH 750
C+H K Q PG++ ++ +K + +E + +RR E E+ R R E
Sbjct: 22 CSHISKPCTQ---PGWQSEIREREREIETRKEGKKERESERKKERR-EREKRKREREKER 77
Query: 751 SKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRM 810
++ R K + RKK + E+ + R+R K KE + K+++ K R
Sbjct: 78 KRE-------RGKKEKKGERKKEERERKK----RRREKENKEGEEKEKRKKKEKKERGRT 126
Query: 811 ALANKPLRRFKQEPEDELPEAPPKT--RESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRR 868
+ K R ++ +E E K RE + R G + E K+K + R
Sbjct: 127 SKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKER 186
Query: 869 KRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHR 927
K+R N++ ++ + ++ E E ++ + + ++ E +R G ER R
Sbjct: 187 KKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKER--GKRERKER 243
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,112,553
Number of Sequences: 37866
Number of extensions: 3188106
Number of successful extensions: 23801
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 157
Number of HSP's successfully gapped in prelim test: 732
Number of HSP's that attempted gapping in prelim test: 18187
Number of HSP's gapped (non-prelim): 5145
length of query: 1265
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1151
effective length of database: 13,930,794
effective search space: 16034343894
effective search space used: 16034343894
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.