Guide to the Human Genome
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Search of human proteins with 52632381

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|52632381 melanoma antigen family D, 1 isoform a [Homo
sapiens]
         (834 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|52632381 melanoma antigen family D, 1 isoform a [Homo sapiens]    1754   0.0  
gi|52632379 melanoma antigen family D, 1 isoform b [Homo sapiens]    1600   0.0  
gi|52632377 melanoma antigen family D, 1 isoform b [Homo sapiens]    1600   0.0  
gi|29337296 melanoma antigen family D, 4B isoform 2 [Homo sapiens]    452   e-127
gi|29337294 melanoma antigen family D, 4B isoform 1 [Homo sapiens]    452   e-127
gi|29337292 melanoma antigen family D, 4B isoform 1 [Homo sapiens]    452   e-127
gi|149274614 melanoma antigen family D, 4 [Homo sapiens]              452   e-127
gi|89276766 trophinin isoform 5 [Homo sapiens]                        404   e-112
gi|29171705 melanoma antigen family D, 2 [Homo sapiens]               370   e-102
gi|19387846 melanoma antigen family D, 2 [Homo sapiens]               370   e-102
gi|41350320 melanoma antigen family D, 2 [Homo sapiens]               370   e-102
gi|29540551 trophinin isoform 2 [Homo sapiens]                        343   3e-94
gi|29540541 trophinin isoform 2 [Homo sapiens]                        343   3e-94
gi|148746206 MAGE-like protein 2 [Homo sapiens]                       212   1e-54
gi|20162572 necdin-like 2 [Homo sapiens]                              203   5e-52
gi|29826296 melanoma antigen family F, 1 [Homo sapiens]               200   4e-51
gi|20143482 melanoma antigen family E, 1 [Homo sapiens]               190   5e-48
gi|73623441 melanoma antigen family B, 10 [Homo sapiens]              174   3e-43
gi|29171714 melanoma antigen family B, 3 [Homo sapiens]               171   2e-42
gi|4505349 necdin [Homo sapiens]                                      169   7e-42
gi|58530863 melanoma antigen family A, 10 [Homo sapiens]              168   2e-41
gi|10567820 melanoma antigen family A, 10 [Homo sapiens]              168   2e-41
gi|27734781 melanoma antigen family B, 18 [Homo sapiens]              168   2e-41
gi|153791873 melanoma antigen family B, 16 [Homo sapiens]             167   3e-41
gi|61744473 melanoma antigen family A, 11 isoform b [Homo sapiens]    166   6e-41
gi|65507078 melanoma antigen family A, 11 isoform a [Homo sapiens]    166   6e-41
gi|4505085 melanoma antigen family B, 4 [Homo sapiens]                166   1e-40
gi|19923308 melanoma antigen family A, 8 [Homo sapiens]               166   1e-40
gi|169216977 PREDICTED: melanoma antigen family B, 17 [Homo sapi...   164   4e-40
gi|169216191 PREDICTED: melanoma antigen family B, 17 [Homo sapi...   164   4e-40

>gi|52632381 melanoma antigen family D, 1 isoform a [Homo sapiens]
          Length = 834

 Score = 1754 bits (4543), Expect = 0.0
 Identities = 834/834 (100%), Positives = 834/834 (100%)

Query: 1   MAQKMDCGAGLLGFQNPDACRAVCHPLPQPPASTLPLSAFPTLCDPPYSQLRDPPAVLSC 60
           MAQKMDCGAGLLGFQNPDACRAVCHPLPQPPASTLPLSAFPTLCDPPYSQLRDPPAVLSC
Sbjct: 1   MAQKMDCGAGLLGFQNPDACRAVCHPLPQPPASTLPLSAFPTLCDPPYSQLRDPPAVLSC 60

Query: 61  YCTPLGASPAPAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMAD 120
           YCTPLGASPAPAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMAD
Sbjct: 61  YCTPLGASPAPAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMAD 120

Query: 121 IQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNA 180
           IQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNA
Sbjct: 121 IQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNA 180

Query: 181 AYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAW 240
           AYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAW
Sbjct: 181 AYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAW 240

Query: 241 NDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTII 300
           NDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTII
Sbjct: 241 NDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTII 300

Query: 301 RGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQN 360
           RGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQN
Sbjct: 301 RGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQN 360

Query: 361 PSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPG 420
           PSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPG
Sbjct: 361 PSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPG 420

Query: 421 PVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPL 480
           PVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPL
Sbjct: 421 PVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPL 480

Query: 481 PPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLML 540
           PPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLML
Sbjct: 481 PPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLML 540

Query: 541 KDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTP 600
           KDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTP
Sbjct: 541 KDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTP 600

Query: 601 ESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLR 660
           ESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLR
Sbjct: 601 ESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLR 660

Query: 661 KLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTA 720
           KLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTA
Sbjct: 661 KLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTA 720

Query: 721 QFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFG 780
           QFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFG
Sbjct: 721 QFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFG 780

Query: 781 DPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE 834
           DPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE
Sbjct: 781 DPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE 834


>gi|52632379 melanoma antigen family D, 1 isoform b [Homo sapiens]
          Length = 778

 Score = 1600 bits (4143), Expect = 0.0
 Identities = 763/763 (100%), Positives = 763/763 (100%)

Query: 72  AEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPK 131
           AEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPK
Sbjct: 16  AEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPK 75

Query: 132 SAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTG 191
           SAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTG
Sbjct: 76  SAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTG 135

Query: 192 ELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADT 251
           ELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADT
Sbjct: 136 ELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADT 195

Query: 252 QTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNL 311
           QTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNL
Sbjct: 196 QTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNL 255

Query: 312 NVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQ 371
           NVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQ
Sbjct: 256 NVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQ 315

Query: 372 TPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNPLAWQ 431
           TPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNPLAWQ
Sbjct: 316 TPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNPLAWQ 375

Query: 432 NPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPI 491
           NPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPI
Sbjct: 376 NPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPI 435

Query: 492 PPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRS 551
           PPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRS
Sbjct: 436 PPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRS 495

Query: 552 EMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTK 611
           EMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTK
Sbjct: 496 EMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTK 555

Query: 612 DTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQK 671
           DTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQK
Sbjct: 556 DTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQK 615

Query: 672 YLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALD 731
           YLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALD
Sbjct: 616 YLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALD 675

Query: 732 ALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFW 791
           ALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFW
Sbjct: 676 ALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFW 735

Query: 792 ARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE 834
           ARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE
Sbjct: 736 ARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE 778


>gi|52632377 melanoma antigen family D, 1 isoform b [Homo sapiens]
          Length = 778

 Score = 1600 bits (4143), Expect = 0.0
 Identities = 763/763 (100%), Positives = 763/763 (100%)

Query: 72  AEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPK 131
           AEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPK
Sbjct: 16  AEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPK 75

Query: 132 SAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTG 191
           SAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTG
Sbjct: 76  SAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTG 135

Query: 192 ELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADT 251
           ELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADT
Sbjct: 136 ELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADT 195

Query: 252 QTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNL 311
           QTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNL
Sbjct: 196 QTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNL 255

Query: 312 NVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQ 371
           NVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQ
Sbjct: 256 NVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQ 315

Query: 372 TPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNPLAWQ 431
           TPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNPLAWQ
Sbjct: 316 TPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNPLAWQ 375

Query: 432 NPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPI 491
           NPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPI
Sbjct: 376 NPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPI 435

Query: 492 PPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRS 551
           PPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRS
Sbjct: 436 PPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRS 495

Query: 552 EMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTK 611
           EMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTK
Sbjct: 496 EMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTK 555

Query: 612 DTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQK 671
           DTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQK
Sbjct: 556 DTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQK 615

Query: 672 YLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALD 731
           YLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALD
Sbjct: 616 YLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALD 675

Query: 732 ALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFW 791
           ALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFW
Sbjct: 676 ALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFW 735

Query: 792 ARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE 834
           ARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE
Sbjct: 736 ARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE 778


>gi|29337296 melanoma antigen family D, 4B isoform 2 [Homo sapiens]
          Length = 739

 Score =  452 bits (1163), Expect = e-127
 Identities = 230/372 (61%), Positives = 272/372 (73%), Gaps = 28/372 (7%)

Query: 491 IPPDWQNLRPSPNLRPS-----PNSRASQNPG----AAQPRDVALLQERANKLVKYLMLK 541
           +PP W+  +PS  +R       P +  SQ P        PR+V LLQERANKLVKYLM+K
Sbjct: 368 VPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPRNVTLLQERANKLVKYLMIK 427

Query: 542 DYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPE 601
           DY K+PIKR++ML+D+IREY + +PEIIERA + LEKKFGI LKEIDKEEHLYIL+ T +
Sbjct: 428 DYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRD 487

Query: 602 SLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRK 661
           S A +LG TKDTP+L LLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHP LGDLRK
Sbjct: 488 SSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRK 547

Query: 662 LLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQ 721
           L+T +FVKQKYL+Y+++PNSNPPEYEFLWGLR+ HETSKM+VLRFIA+ Q RDPR+W A 
Sbjct: 548 LITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAH 607

Query: 722 FMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGD 781
           F+EA D+A   +D   AE  ARA+ R +M IGDEA+ G WSWDDI+ ELLTWDE+GDFGD
Sbjct: 608 FLEAVDDAFKTMDVDMAEEHARAQMRAQMNIGDEALIGRWSWDDIQVELLTWDEDGDFGD 667

Query: 782 PWSRIPFTFWARYHQ-----NARSRFPQTFAGPIIGPGGTASANF--------------A 822
            W+RIPF FWARYHQ     N  +R     AG   G  G AS +               A
Sbjct: 668 AWARIPFAFWARYHQYILNSNRANRRATWRAGVSSGTNGGASTSVLDGPSTSSTIRTRNA 727

Query: 823 ANFGAIGFFWVE 834
           A  GA  F W++
Sbjct: 728 ARAGASFFSWIQ 739



 Score =  101 bits (252), Expect = 3e-21
 Identities = 90/298 (30%), Positives = 138/298 (46%), Gaps = 38/298 (12%)

Query: 67  ASPAPAEASVEDSALLMQTLMEAIQIS--EAPPTNQATAA---------ASPQSSQPPTA 115
           A  A A A    S ++    +   Q+S  +  PT  A  A         ASPQ+SQ    
Sbjct: 117 ARAAAAAARTAFSQVVASHRVATPQVSGEDTQPTTYAAEAQGPTPEPPLASPQTSQMLVT 176

Query: 116 NEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATP 175
           ++MA  +  A +A+ ++    Q A T+GP+    FSQA  A++V   +P  AF       
Sbjct: 177 SKMAAPEAPATSAQSQTGSPAQEAATEGPSSACAFSQAPCAREVDANRPSTAF------- 229

Query: 176 KGPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKT 235
            G N  +DF+Q A    +A  + +    AQ A T+ GP+A     Q+    ++A +RPK 
Sbjct: 230 LGQNDVFDFTQPAGVSGMAFPRPKRPAPAQEAATE-GPSAASGVPQTGPGREVAATRPK- 287

Query: 236 PFKAWNDTTKAPTADTQTQNVN-QAKMATSQADIETDPGISEPDGATAQTSADGSQAQNL 294
                  TTK+  A  +T+ V  Q  +A + A  +    I EP+GA A T+       + 
Sbjct: 288 -------TTKSGKALAKTRWVEPQNVVAAAAAKAKMATSIPEPEGAAAATA-----QHSA 335

Query: 295 ESRTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQ-----NPPGAP 347
           E    + GKRT+K  +L+ E  SS ++R  P    TWR++   +T +      PP AP
Sbjct: 336 EPWARMGGKRTKKSKHLDDEYESSEEERETPAVPPTWRASQPSLTVRAQLAPRPPMAP 393


>gi|29337294 melanoma antigen family D, 4B isoform 1 [Homo sapiens]
          Length = 741

 Score =  452 bits (1163), Expect = e-127
 Identities = 230/372 (61%), Positives = 272/372 (73%), Gaps = 28/372 (7%)

Query: 491 IPPDWQNLRPSPNLRPS-----PNSRASQNPG----AAQPRDVALLQERANKLVKYLMLK 541
           +PP W+  +PS  +R       P +  SQ P        PR+V LLQERANKLVKYLM+K
Sbjct: 368 VPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPRNVTLLQERANKLVKYLMIK 427

Query: 542 DYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPE 601
           DY K+PIKR++ML+D+IREY + +PEIIERA + LEKKFGI LKEIDKEEHLYIL+ T +
Sbjct: 428 DYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRD 487

Query: 602 SLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRK 661
           S A +LG TKDTP+L LLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHP LGDLRK
Sbjct: 488 SSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRK 547

Query: 662 LLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQ 721
           L+T +FVKQKYL+Y+++PNSNPPEYEFLWGLR+ HETSKM+VLRFIA+ Q RDPR+W A 
Sbjct: 548 LITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAH 607

Query: 722 FMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGD 781
           F+EA D+A   +D   AE  ARA+ R +M IGDEA+ G WSWDDI+ ELLTWDE+GDFGD
Sbjct: 608 FLEAVDDAFKTMDVDMAEEHARAQMRAQMNIGDEALIGRWSWDDIQVELLTWDEDGDFGD 667

Query: 782 PWSRIPFTFWARYHQ-----NARSRFPQTFAGPIIGPGGTASANF--------------A 822
            W+RIPF FWARYHQ     N  +R     AG   G  G AS +               A
Sbjct: 668 AWARIPFAFWARYHQYILNSNRANRRATWRAGVSSGTNGGASTSVLDGPSTSSTIRTRNA 727

Query: 823 ANFGAIGFFWVE 834
           A  GA  F W++
Sbjct: 728 ARAGASFFSWIQ 739



 Score =  101 bits (252), Expect = 3e-21
 Identities = 90/298 (30%), Positives = 138/298 (46%), Gaps = 38/298 (12%)

Query: 67  ASPAPAEASVEDSALLMQTLMEAIQIS--EAPPTNQATAA---------ASPQSSQPPTA 115
           A  A A A    S ++    +   Q+S  +  PT  A  A         ASPQ+SQ    
Sbjct: 117 ARAAAAAARTAFSQVVASHRVATPQVSGEDTQPTTYAAEAQGPTPEPPLASPQTSQMLVT 176

Query: 116 NEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATP 175
           ++MA  +  A +A+ ++    Q A T+GP+    FSQA  A++V   +P  AF       
Sbjct: 177 SKMAAPEAPATSAQSQTGSPAQEAATEGPSSACAFSQAPCAREVDANRPSTAF------- 229

Query: 176 KGPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKT 235
            G N  +DF+Q A    +A  + +    AQ A T+ GP+A     Q+    ++A +RPK 
Sbjct: 230 LGQNDVFDFTQPAGVSGMAFPRPKRPAPAQEAATE-GPSAASGVPQTGPGREVAATRPK- 287

Query: 236 PFKAWNDTTKAPTADTQTQNVN-QAKMATSQADIETDPGISEPDGATAQTSADGSQAQNL 294
                  TTK+  A  +T+ V  Q  +A + A  +    I EP+GA A T+       + 
Sbjct: 288 -------TTKSGKALAKTRWVEPQNVVAAAAAKAKMATSIPEPEGAAAATA-----QHSA 335

Query: 295 ESRTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQ-----NPPGAP 347
           E    + GKRT+K  +L+ E  SS ++R  P    TWR++   +T +      PP AP
Sbjct: 336 EPWARMGGKRTKKSKHLDDEYESSEEERETPAVPPTWRASQPSLTVRAQLAPRPPMAP 393


>gi|29337292 melanoma antigen family D, 4B isoform 1 [Homo sapiens]
          Length = 741

 Score =  452 bits (1163), Expect = e-127
 Identities = 230/372 (61%), Positives = 272/372 (73%), Gaps = 28/372 (7%)

Query: 491 IPPDWQNLRPSPNLRPS-----PNSRASQNPG----AAQPRDVALLQERANKLVKYLMLK 541
           +PP W+  +PS  +R       P +  SQ P        PR+V LLQERANKLVKYLM+K
Sbjct: 368 VPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPRNVTLLQERANKLVKYLMIK 427

Query: 542 DYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPE 601
           DY K+PIKR++ML+D+IREY + +PEIIERA + LEKKFGI LKEIDKEEHLYIL+ T +
Sbjct: 428 DYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRD 487

Query: 602 SLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRK 661
           S A +LG TKDTP+L LLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHP LGDLRK
Sbjct: 488 SSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRK 547

Query: 662 LLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQ 721
           L+T +FVKQKYL+Y+++PNSNPPEYEFLWGLR+ HETSKM+VLRFIA+ Q RDPR+W A 
Sbjct: 548 LITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAH 607

Query: 722 FMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGD 781
           F+EA D+A   +D   AE  ARA+ R +M IGDEA+ G WSWDDI+ ELLTWDE+GDFGD
Sbjct: 608 FLEAVDDAFKTMDVDMAEEHARAQMRAQMNIGDEALIGRWSWDDIQVELLTWDEDGDFGD 667

Query: 782 PWSRIPFTFWARYHQ-----NARSRFPQTFAGPIIGPGGTASANF--------------A 822
            W+RIPF FWARYHQ     N  +R     AG   G  G AS +               A
Sbjct: 668 AWARIPFAFWARYHQYILNSNRANRRATWRAGVSSGTNGGASTSVLDGPSTSSTIRTRNA 727

Query: 823 ANFGAIGFFWVE 834
           A  GA  F W++
Sbjct: 728 ARAGASFFSWIQ 739



 Score =  101 bits (252), Expect = 3e-21
 Identities = 90/298 (30%), Positives = 138/298 (46%), Gaps = 38/298 (12%)

Query: 67  ASPAPAEASVEDSALLMQTLMEAIQIS--EAPPTNQATAA---------ASPQSSQPPTA 115
           A  A A A    S ++    +   Q+S  +  PT  A  A         ASPQ+SQ    
Sbjct: 117 ARAAAAAARTAFSQVVASHRVATPQVSGEDTQPTTYAAEAQGPTPEPPLASPQTSQMLVT 176

Query: 116 NEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATP 175
           ++MA  +  A +A+ ++    Q A T+GP+    FSQA  A++V   +P  AF       
Sbjct: 177 SKMAAPEAPATSAQSQTGSPAQEAATEGPSSACAFSQAPCAREVDANRPSTAF------- 229

Query: 176 KGPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKT 235
            G N  +DF+Q A    +A  + +    AQ A T+ GP+A     Q+    ++A +RPK 
Sbjct: 230 LGQNDVFDFTQPAGVSGMAFPRPKRPAPAQEAATE-GPSAASGVPQTGPGREVAATRPK- 287

Query: 236 PFKAWNDTTKAPTADTQTQNVN-QAKMATSQADIETDPGISEPDGATAQTSADGSQAQNL 294
                  TTK+  A  +T+ V  Q  +A + A  +    I EP+GA A T+       + 
Sbjct: 288 -------TTKSGKALAKTRWVEPQNVVAAAAAKAKMATSIPEPEGAAAATA-----QHSA 335

Query: 295 ESRTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQ-----NPPGAP 347
           E    + GKRT+K  +L+ E  SS ++R  P    TWR++   +T +      PP AP
Sbjct: 336 EPWARMGGKRTKKSKHLDDEYESSEEERETPAVPPTWRASQPSLTVRAQLAPRPPMAP 393


>gi|149274614 melanoma antigen family D, 4 [Homo sapiens]
          Length = 739

 Score =  452 bits (1163), Expect = e-127
 Identities = 230/372 (61%), Positives = 272/372 (73%), Gaps = 28/372 (7%)

Query: 491 IPPDWQNLRPSPNLRPS-----PNSRASQNPG----AAQPRDVALLQERANKLVKYLMLK 541
           +PP W+  +PS  +R       P +  SQ P        PR+V LLQERANKLVKYLM+K
Sbjct: 368 VPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPRNVTLLQERANKLVKYLMIK 427

Query: 542 DYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPE 601
           DY K+PIKR++ML+D+IREY + +PEIIERA + LEKKFGI LKEIDKEEHLYIL+ T +
Sbjct: 428 DYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRD 487

Query: 602 SLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRK 661
           S A +LG TKDTP+L LLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHP LGDLRK
Sbjct: 488 SSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRK 547

Query: 662 LLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQ 721
           L+T +FVKQKYL+Y+++PNSNPPEYEFLWGLR+ HETSKM+VLRFIA+ Q RDPR+W A 
Sbjct: 548 LITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAH 607

Query: 722 FMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGD 781
           F+EA D+A   +D   AE  ARA+ R +M IGDEA+ G WSWDDI+ ELLTWDE+GDFGD
Sbjct: 608 FLEAVDDAFKTMDVDMAEEHARAQMRAQMNIGDEALIGRWSWDDIQVELLTWDEDGDFGD 667

Query: 782 PWSRIPFTFWARYHQ-----NARSRFPQTFAGPIIGPGGTASANF--------------A 822
            W+RIPF FWARYHQ     N  +R     AG   G  G AS +               A
Sbjct: 668 AWARIPFAFWARYHQYILNSNRANRRATWRAGVSSGTNGGASTSVLDGPSTSSTIRTRNA 727

Query: 823 ANFGAIGFFWVE 834
           A  GA  F W++
Sbjct: 728 ARAGASFFSWIQ 739



 Score =  101 bits (252), Expect = 3e-21
 Identities = 90/298 (30%), Positives = 138/298 (46%), Gaps = 38/298 (12%)

Query: 67  ASPAPAEASVEDSALLMQTLMEAIQIS--EAPPTNQATAA---------ASPQSSQPPTA 115
           A  A A A    S ++    +   Q+S  +  PT  A  A         ASPQ+SQ    
Sbjct: 117 ARAAAAAARTAFSQVVASHRVATPQVSGEDTQPTTYAAEAQGPTPEPPLASPQTSQMLVT 176

Query: 116 NEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATP 175
           ++MA  +  A +A+ ++    Q A T+GP+    FSQA  A++V   +P  AF       
Sbjct: 177 SKMAAPEAPATSAQSQTGSPAQEAATEGPSSACAFSQAPCAREVDANRPSTAF------- 229

Query: 176 KGPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKT 235
            G N  +DF+Q A    +A  + +    AQ A T+ GP+A     Q+    ++A +RPK 
Sbjct: 230 LGQNDVFDFTQPAGVSGMAFPRPKRPAPAQEAATE-GPSAASGVPQTGPGREVAATRPK- 287

Query: 236 PFKAWNDTTKAPTADTQTQNVN-QAKMATSQADIETDPGISEPDGATAQTSADGSQAQNL 294
                  TTK+  A  +T+ V  Q  +A + A  +    I EP+GA A T+       + 
Sbjct: 288 -------TTKSGKALAKTRWVEPQNVVAAAAAKAKMATSIPEPEGAAAATA-----QHSA 335

Query: 295 ESRTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQ-----NPPGAP 347
           E    + GKRT+K  +L+ E  SS ++R  P    TWR++   +T +      PP AP
Sbjct: 336 EPWARMGGKRTKKSKHLDDEYESSEEERETPAVPPTWRASQPSLTVRAQLAPRPPMAP 393


>gi|89276766 trophinin isoform 5 [Homo sapiens]
          Length = 1431

 Score =  404 bits (1038), Expect = e-112
 Identities = 194/280 (69%), Positives = 230/280 (82%)

Query: 519 AQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEK 578
           A PRDVA+LQERANKLVKYL++KD TK+PIKRS+MLRD+I+EY + +PEIIERA + LEK
Sbjct: 436 APPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEK 495

Query: 579 KFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVL 638
            F + LKEIDK+  LYILIST ES AGILGTTKDTPKLGLL+VIL VIFMNGN+ASEAV+
Sbjct: 496 MFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVI 555

Query: 639 WEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHET 698
           WE LRK+GLRPGVRH L G++RKL+T EFVKQKYL+Y+RVPNS PPEYEF WGLRSYHET
Sbjct: 556 WEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHET 615

Query: 699 SKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVS 758
           SKMKVL+F   VQK+DP+DW  Q+ EA +  + A   A AEAEARAEAR +MGIG+EAV+
Sbjct: 616 SKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEARAQMGIGEEAVA 675

Query: 759 GPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNA 798
           GPW+WDD++ + LT +E GD    WSR  F   AR  +NA
Sbjct: 676 GPWNWDDMDIDCLTREELGDDAQAWSRFSFEIEARAQENA 715



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 72/258 (27%), Positives = 106/258 (41%), Gaps = 48/258 (18%)

Query: 92  ISEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFS 151
           I+ A   + A  A    ++Q    NE A I  +AA+ R K A K +    K  N   +  
Sbjct: 216 IASATEVSLAATATHTATTQGQITNETASIHTTAASIRTKKASKARKTIAKVINTDTEHI 275

Query: 152 QAHNAKDVPNTQPKAAF--------KSQNATPKGPNAAYDFSQAATTGELAANKSEMAFK 203
           +A N  D    Q +A+         K + A  +GPN+  + S+A    ++  N+      
Sbjct: 276 EALNVTDAATRQIEASVVAIRPKKSKGKKAASRGPNSVSEISEAPLATQIVTNQ------ 329

Query: 204 AQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVNQ---AK 260
           A  AT +V                      K   +A    TKA   ++QT N +Q   AK
Sbjct: 330 ALAATLRV----------------------KRGSRARKAATKARATESQTPNADQGAQAK 367

Query: 261 MATSQADIETDPGISEPDGATAQTSADGSQAQ-NLESRTIIRGKRTRKINNLNVEENSSG 319
           +A++Q ++     +     A  Q  AD   AQ +LE  T  RGKR RK  +LN +E S  
Sbjct: 368 IASAQTNVSA---LETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKHLNGDERSGS 424

Query: 320 DQRRAPLAAGTWRSAPVP 337
           + RR P     W   P P
Sbjct: 425 NYRRIP-----WGRRPAP 437


>gi|29171705 melanoma antigen family D, 2 [Homo sapiens]
          Length = 606

 Score =  370 bits (951), Expect = e-102
 Identities = 198/327 (60%), Positives = 237/327 (72%), Gaps = 16/327 (4%)

Query: 505 RPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDV 564
           R +   ++SQ P A  PRDVALLQ RAN LVKYL+ KD TK+PIKRS+ML+DII+EYTDV
Sbjct: 257 RRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDV 316

Query: 565 YPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESL-AGILGTTKDTPKLGLLLVIL 623
           YPEIIERA + LEK FGIQLKEIDK +HLYIL+ST E   AGILGTTKD+PKLGLL+V+L
Sbjct: 317 YPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLL 376

Query: 624 GVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNP 683
            +IFMNGNR+SEAV+WE LRK+GLRPG+ H L GD++KL+T EFVKQKYLDY RVPNSNP
Sbjct: 377 SIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNP 436

Query: 684 PEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEAR 743
           PEYEF WGLRSY+ETSKMKVL+F  +VQK+DP++W AQ+ EA +  L A   AAAEA+AR
Sbjct: 437 PEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKAR 496

Query: 744 AEARTRMGI--GDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNAR-S 800
           AE R RMGI  G E  +GP +WD           E D G PW++      A     A+ S
Sbjct: 497 AEIRARMGIGLGSENAAGPCNWD-----------EADIG-PWAKARIQAGAEAKAKAQES 544

Query: 801 RFPQTFAGPIIGPGGTASANFAANFGA 827
               T A        +ASA+ +  F A
Sbjct: 545 GSASTGASTSTNNSASASASTSGGFSA 571



 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 78/319 (24%), Positives = 122/319 (38%), Gaps = 77/319 (24%)

Query: 66  GASPAPAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMADIQVSA 125
           G +   AEAS +DS+ +MQTL+   Q  E P T +A+ A               D++VS 
Sbjct: 10  GLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSE----------DVKVSK 59

Query: 126 AAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFS 185
           A+   K+                + S+   A++ P TQ  +                  +
Sbjct: 60  ASGVSKAT---------------EVSKTPEAREAPATQASST-----------------T 87

Query: 186 QAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTK 245
           Q   T  LAA    +A     A TK             NA+  A + P T  K  +    
Sbjct: 88  QLTDTQVLAAENKSLA-----ADTK-----------KQNADPQAVTMPATETKKVSHV-- 129

Query: 246 APTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRT 305
              ADT+   VN     T  A  +      EP+ A AQ+       +N ++R  ++ K+ 
Sbjct: 130 ---ADTK---VNTKAQETEAAPSQAPADEPEPESAAAQSQ------ENQDTRPKVKAKKA 177

Query: 306 RKINNLNVEENSSGDQRRAPLAAGTWR-SAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGW 364
           RK+ +L+ EE+ S DQ +A    G  R S  +  +        P   W    +    + W
Sbjct: 178 RKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAW 237

Query: 365 QNQTARQTPPARQSPPARQ 383
               AR+   + +SP AR+
Sbjct: 238 ----ARRALLSLRSPKARR 252


>gi|19387846 melanoma antigen family D, 2 [Homo sapiens]
          Length = 606

 Score =  370 bits (951), Expect = e-102
 Identities = 198/327 (60%), Positives = 237/327 (72%), Gaps = 16/327 (4%)

Query: 505 RPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDV 564
           R +   ++SQ P A  PRDVALLQ RAN LVKYL+ KD TK+PIKRS+ML+DII+EYTDV
Sbjct: 257 RRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDV 316

Query: 565 YPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESL-AGILGTTKDTPKLGLLLVIL 623
           YPEIIERA + LEK FGIQLKEIDK +HLYIL+ST E   AGILGTTKD+PKLGLL+V+L
Sbjct: 317 YPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLL 376

Query: 624 GVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNP 683
            +IFMNGNR+SEAV+WE LRK+GLRPG+ H L GD++KL+T EFVKQKYLDY RVPNSNP
Sbjct: 377 SIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNP 436

Query: 684 PEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEAR 743
           PEYEF WGLRSY+ETSKMKVL+F  +VQK+DP++W AQ+ EA +  L A   AAAEA+AR
Sbjct: 437 PEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKAR 496

Query: 744 AEARTRMGI--GDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNAR-S 800
           AE R RMGI  G E  +GP +WD           E D G PW++      A     A+ S
Sbjct: 497 AEIRARMGIGLGSENAAGPCNWD-----------EADIG-PWAKARIQAGAEAKAKAQES 544

Query: 801 RFPQTFAGPIIGPGGTASANFAANFGA 827
               T A        +ASA+ +  F A
Sbjct: 545 GSASTGASTSTNNSASASASTSGGFSA 571



 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 78/319 (24%), Positives = 122/319 (38%), Gaps = 77/319 (24%)

Query: 66  GASPAPAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMADIQVSA 125
           G +   AEAS +DS+ +MQTL+   Q  E P T +A+ A               D++VS 
Sbjct: 10  GLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSE----------DVKVSK 59

Query: 126 AAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFS 185
           A+   K+                + S+   A++ P TQ  +                  +
Sbjct: 60  ASGVSKAT---------------EVSKTPEAREAPATQASST-----------------T 87

Query: 186 QAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTK 245
           Q   T  LAA    +A     A TK             NA+  A + P T  K  +    
Sbjct: 88  QLTDTQVLAAENKSLA-----ADTK-----------KQNADPQAVTMPATETKKVSHV-- 129

Query: 246 APTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRT 305
              ADT+   VN     T  A  +      EP+ A AQ+       +N ++R  ++ K+ 
Sbjct: 130 ---ADTK---VNTKAQETEAAPSQAPADEPEPESAAAQSQ------ENQDTRPKVKAKKA 177

Query: 306 RKINNLNVEENSSGDQRRAPLAAGTWR-SAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGW 364
           RK+ +L+ EE+ S DQ +A    G  R S  +  +        P   W    +    + W
Sbjct: 178 RKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAW 237

Query: 365 QNQTARQTPPARQSPPARQ 383
               AR+   + +SP AR+
Sbjct: 238 ----ARRALLSLRSPKARR 252


>gi|41350320 melanoma antigen family D, 2 [Homo sapiens]
          Length = 606

 Score =  370 bits (951), Expect = e-102
 Identities = 198/327 (60%), Positives = 237/327 (72%), Gaps = 16/327 (4%)

Query: 505 RPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDV 564
           R +   ++SQ P A  PRDVALLQ RAN LVKYL+ KD TK+PIKRS+ML+DII+EYTDV
Sbjct: 257 RRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDV 316

Query: 565 YPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESL-AGILGTTKDTPKLGLLLVIL 623
           YPEIIERA + LEK FGIQLKEIDK +HLYIL+ST E   AGILGTTKD+PKLGLL+V+L
Sbjct: 317 YPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLL 376

Query: 624 GVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNP 683
            +IFMNGNR+SEAV+WE LRK+GLRPG+ H L GD++KL+T EFVKQKYLDY RVPNSNP
Sbjct: 377 SIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNP 436

Query: 684 PEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEAR 743
           PEYEF WGLRSY+ETSKMKVL+F  +VQK+DP++W AQ+ EA +  L A   AAAEA+AR
Sbjct: 437 PEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKAR 496

Query: 744 AEARTRMGI--GDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNAR-S 800
           AE R RMGI  G E  +GP +WD           E D G PW++      A     A+ S
Sbjct: 497 AEIRARMGIGLGSENAAGPCNWD-----------EADIG-PWAKARIQAGAEAKAKAQES 544

Query: 801 RFPQTFAGPIIGPGGTASANFAANFGA 827
               T A        +ASA+ +  F A
Sbjct: 545 GSASTGASTSTNNSASASASTSGGFSA 571



 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 78/319 (24%), Positives = 122/319 (38%), Gaps = 77/319 (24%)

Query: 66  GASPAPAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMADIQVSA 125
           G +   AEAS +DS+ +MQTL+   Q  E P T +A+ A               D++VS 
Sbjct: 10  GLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSE----------DVKVSK 59

Query: 126 AAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFS 185
           A+   K+                + S+   A++ P TQ  +                  +
Sbjct: 60  ASGVSKAT---------------EVSKTPEAREAPATQASST-----------------T 87

Query: 186 QAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTK 245
           Q   T  LAA    +A     A TK             NA+  A + P T  K  +    
Sbjct: 88  QLTDTQVLAAENKSLA-----ADTK-----------KQNADPQAVTMPATETKKVSHV-- 129

Query: 246 APTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRT 305
              ADT+   VN     T  A  +      EP+ A AQ+       +N ++R  ++ K+ 
Sbjct: 130 ---ADTK---VNTKAQETEAAPSQAPADEPEPESAAAQSQ------ENQDTRPKVKAKKA 177

Query: 306 RKINNLNVEENSSGDQRRAPLAAGTWR-SAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGW 364
           RK+ +L+ EE+ S DQ +A    G  R S  +  +        P   W    +    + W
Sbjct: 178 RKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAW 237

Query: 365 QNQTARQTPPARQSPPARQ 383
               AR+   + +SP AR+
Sbjct: 238 ----ARRALLSLRSPKARR 252


>gi|29540551 trophinin isoform 2 [Homo sapiens]
          Length = 706

 Score =  343 bits (881), Expect = 3e-94
 Identities = 166/227 (73%), Positives = 193/227 (85%)

Query: 519 AQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEK 578
           A PRDVA+LQERANKLVKYL++KD TK+PIKRS+MLRD+I+EY + +PEIIERA + LEK
Sbjct: 436 APPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEK 495

Query: 579 KFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVL 638
            F + LKEIDK+  LYILIST ES AGILGTTKDTPKLGLL+VIL VIFMNGN+ASEAV+
Sbjct: 496 MFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVI 555

Query: 639 WEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHET 698
           WE LRK+GLRPGVRH L G++RKL+T EFVKQKYL+Y+RVPNS PPEYEF WGLRSYHET
Sbjct: 556 WEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHET 615

Query: 699 SKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAE 745
           SKMKVL+F   VQK+DP+DW  Q+ EA +  + A   A AEAEARAE
Sbjct: 616 SKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAE 662



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 72/258 (27%), Positives = 106/258 (41%), Gaps = 48/258 (18%)

Query: 92  ISEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFS 151
           I+ A   + A  A    ++Q    NE A I  +AA+ R K A K +    K  N   +  
Sbjct: 216 IASATEVSLAATATHTATTQGQITNETASIHTTAASIRTKKASKARKTIAKVINTDTEHI 275

Query: 152 QAHNAKDVPNTQPKAAF--------KSQNATPKGPNAAYDFSQAATTGELAANKSEMAFK 203
           +A N  D    Q +A+         K + A  +GPN+  + S+A    ++  N+      
Sbjct: 276 EALNVTDAATRQIEASVVAIRPKKSKGKKAASRGPNSVSEISEAPLATQIVTNQ------ 329

Query: 204 AQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVNQ---AK 260
           A  AT +V                      K   +A    TKA   ++QT N +Q   AK
Sbjct: 330 ALAATLRV----------------------KRGSRARKAATKARATESQTPNADQGAQAK 367

Query: 261 MATSQADIETDPGISEPDGATAQTSADGSQAQ-NLESRTIIRGKRTRKINNLNVEENSSG 319
           +A++Q ++     +     A  Q  AD   AQ +LE  T  RGKR RK  +LN +E S  
Sbjct: 368 IASAQTNVSA---LETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKHLNGDERSGS 424

Query: 320 DQRRAPLAAGTWRSAPVP 337
           + RR P     W   P P
Sbjct: 425 NYRRIP-----WGRRPAP 437


>gi|29540541 trophinin isoform 2 [Homo sapiens]
          Length = 706

 Score =  343 bits (881), Expect = 3e-94
 Identities = 166/227 (73%), Positives = 193/227 (85%)

Query: 519 AQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEK 578
           A PRDVA+LQERANKLVKYL++KD TK+PIKRS+MLRD+I+EY + +PEIIERA + LEK
Sbjct: 436 APPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEK 495

Query: 579 KFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVL 638
            F + LKEIDK+  LYILIST ES AGILGTTKDTPKLGLL+VIL VIFMNGN+ASEAV+
Sbjct: 496 MFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVI 555

Query: 639 WEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHET 698
           WE LRK+GLRPGVRH L G++RKL+T EFVKQKYL+Y+RVPNS PPEYEF WGLRSYHET
Sbjct: 556 WEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHET 615

Query: 699 SKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAE 745
           SKMKVL+F   VQK+DP+DW  Q+ EA +  + A   A AEAEARAE
Sbjct: 616 SKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAE 662



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 72/258 (27%), Positives = 106/258 (41%), Gaps = 48/258 (18%)

Query: 92  ISEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFS 151
           I+ A   + A  A    ++Q    NE A I  +AA+ R K A K +    K  N   +  
Sbjct: 216 IASATEVSLAATATHTATTQGQITNETASIHTTAASIRTKKASKARKTIAKVINTDTEHI 275

Query: 152 QAHNAKDVPNTQPKAAF--------KSQNATPKGPNAAYDFSQAATTGELAANKSEMAFK 203
           +A N  D    Q +A+         K + A  +GPN+  + S+A    ++  N+      
Sbjct: 276 EALNVTDAATRQIEASVVAIRPKKSKGKKAASRGPNSVSEISEAPLATQIVTNQ------ 329

Query: 204 AQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVNQ---AK 260
           A  AT +V                      K   +A    TKA   ++QT N +Q   AK
Sbjct: 330 ALAATLRV----------------------KRGSRARKAATKARATESQTPNADQGAQAK 367

Query: 261 MATSQADIETDPGISEPDGATAQTSADGSQAQ-NLESRTIIRGKRTRKINNLNVEENSSG 319
           +A++Q ++     +     A  Q  AD   AQ +LE  T  RGKR RK  +LN +E S  
Sbjct: 368 IASAQTNVSA---LETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKHLNGDERSGS 424

Query: 320 DQRRAPLAAGTWRSAPVP 337
           + RR P     W   P P
Sbjct: 425 NYRRIP-----WGRRPAP 437


>gi|148746206 MAGE-like protein 2 [Homo sapiens]
          Length = 646

 Score =  212 bits (539), Expect = 1e-54
 Identities = 126/324 (38%), Positives = 180/324 (55%), Gaps = 22/324 (6%)

Query: 418 WPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTD 477
           W GP  W N     N   W+     Q    W+ P   +G   W  P    +   W  P+ 
Sbjct: 305 WQGPRPWEN----LNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPS- 359

Query: 478 WPLPPDWIPADWPIPPDWQNL----RPSPNL--------RPSPNSRASQNPGAAQPRDVA 525
                 W  + W  P   + L     P  +L          SP S A+Q+    + + ++
Sbjct: 360 ----ASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVEAQPLS 415

Query: 526 LLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLK 585
            L ERAN LV++L++KD  KVP++RSEM++ I+REY D   +II RA   LE  FG QLK
Sbjct: 416 PLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLK 475

Query: 586 EIDKEEHLYILISTPESLAG-ILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRK 644
           EID + H YI+I+      G ++ +  D PK GLL+V+L +IFM GN   E +++  L K
Sbjct: 476 EIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFK 535

Query: 645 MGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVL 704
           +GL     + L G+ +KL+T  FV+QKYL+YRR+P + P EYEFLWG R++ ETSKM VL
Sbjct: 536 LGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVL 595

Query: 705 RFIAEVQKRDPRDWTAQFMEAADE 728
           RF+A++ K+DP+ W   ++EA  E
Sbjct: 596 RFLAKLHKKDPQSWPFHYLEALAE 619



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 76/363 (20%), Positives = 116/363 (31%), Gaps = 46/363 (12%)

Query: 46  PPYSQLRDPPAVLSCYCTPLGASPAPAEASVEDSALLMQTLMEAIQISEAP--PTNQATA 103
           PP  QL  P           GA P+     ++      Q      ++   P  P+ QA  
Sbjct: 37  PPLVQLEQPFQ---------GAPPSQKAVQIQLPPQQAQASGPQAEVPTLPLQPSWQAPP 87

Query: 104 AASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQ 163
           A       PP A     +  + +   P    +  +   +G +     S          ++
Sbjct: 88  AVLQAQPGPPVAAANFPLGSAKSLMTPSGECRASSIDRRGSSKERRTSSKERRAP---SK 144

Query: 164 PKAAFKSQNATPKGPNAAYDFSQAA-----TTGELAANKSEMAFKAQNATTKVGPNATYN 218
            +  F +    PK  +AA     AA      T E  A  S +      AT++  P +   
Sbjct: 145 DRMIFAATFCAPKAVSAARAHLPAAWKNLPATPETFAPSSSVF----PATSQFQPASLNA 200

Query: 219 FSQSLNANDLANSRP---KTPFKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGIS 275
           F     A++   S P   + PF         P       N ++A  A         P   
Sbjct: 201 FKGPSAASETPKSLPYALQDPFACVEALPAVPWVPQPNMNASKASQAV--------PTFL 252

Query: 276 EPDGATAQTSADGSQAQNLESRTIIR-GKRTRKINNLNVEENSSGDQRRAPLAAGTWRSA 334
               A  Q +A   +A         R GK TRK  +L  +E+S G      LA   W+  
Sbjct: 253 MATAAAPQATATTQEASKTSVEPPRRSGKATRKKKHLEAQEDSRGHT----LAFHDWQG- 307

Query: 335 PVPVTTQNPPGAPPNVLWQTPLAWQNP------SGWQNQTARQTPPARQSPPARQTPPAW 388
           P P    N          Q    W++P      SGW+  +  +     + P A     AW
Sbjct: 308 PRPWENLNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPSASWALSAW 367

Query: 389 QNP 391
           + P
Sbjct: 368 EGP 370


>gi|20162572 necdin-like 2 [Homo sapiens]
          Length = 304

 Score =  203 bits (517), Expect = 5e-52
 Identities = 100/227 (44%), Positives = 158/227 (69%), Gaps = 4/227 (1%)

Query: 506 PSPN-SRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDV 564
           PSP  +R +Q   A  PR    L+ + ++LV++L++KD  K+PIKR+++L+ +I +Y D+
Sbjct: 63  PSPQGARRAQAAPAVGPRSQKQLELKVSELVQFLLIKDQKKIPIKRADILKHVIGDYKDI 122

Query: 565 YPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTKD--TPKLGLLLVI 622
           +P++ +RA   L+  FG +L E++ + + YILI+T E +        D  TP  GLL+++
Sbjct: 123 FPDLFKRAAERLQYVFGYKLVELEPKSNTYILINTLEPVEEDAEMRGDQGTPTTGLLMIV 182

Query: 623 LGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSN 682
           LG+IFM GN   E   W+ LR++G+ P  +H + GD +KL+T +FV+Q+YL+YRR+P+++
Sbjct: 183 LGLIFMKGNTIKETEAWDFLRRLGVYPTKKHLIFGDPKKLITEDFVRQRYLEYRRIPHTD 242

Query: 683 PPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEA-ADE 728
           P +YEF WG R+  ETSKMKVL+F+A+V  +DP+DW AQ+ EA ADE
Sbjct: 243 PVDYEFQWGPRTNLETSKMKVLKFVAKVHNQDPKDWPAQYCEALADE 289


>gi|29826296 melanoma antigen family F, 1 [Homo sapiens]
          Length = 307

 Score =  200 bits (509), Expect = 4e-51
 Identities = 113/252 (44%), Positives = 158/252 (62%), Gaps = 15/252 (5%)

Query: 510 SRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEII 569
           +RA      A+ R    L     +LV++L++KD  K PI RSEM++ +I +   ++P+II
Sbjct: 59  ARALAAKALARRRAYRRLNRTVAELVQFLLVKDKKKSPITRSEMVKYVIGDLKILFPDII 118

Query: 570 ERACFVLEKKFGIQLKEIDKEEHLYILIST--------PESLAGILGTTKDTPKLGLLLV 621
            RA   L   FG +LK+ D++ H YILI+          E L G      D P+LGLL++
Sbjct: 119 ARAAEHLRYVFGFELKQFDRKHHTYILINKLKPLEEEEEEDLGG------DGPRLGLLMM 172

Query: 622 ILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNS 681
           ILG+I+M GN A EA +WE LR++G++P   H L G  ++L+  +FV+Q+YL YRRVP++
Sbjct: 173 ILGLIYMRGNSAREAQVWEMLRRLGVQPSKYHFLFGYPKRLIMEDFVQQRYLSYRRVPHT 232

Query: 682 NPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEA-ADEALDALDAAAAEA 740
           NPPEYEF WG RS  E SKM+VL F+A++ K++P+ W  Q+ EA ADEA  A   A AEA
Sbjct: 233 NPPEYEFSWGPRSNLEISKMEVLGFVAKLHKKEPQHWPVQYREALADEADRARAKARAEA 292

Query: 741 EARAEARTRMGI 752
             RA A  R GI
Sbjct: 293 SMRARASARAGI 304


>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
          Length = 957

 Score =  190 bits (482), Expect = 5e-48
 Identities = 199/718 (27%), Positives = 310/718 (43%), Gaps = 76/718 (10%)

Query: 45  DPPYSQLRDPPA---VLSCYCTPLGASPAPAEASVED-SALLMQTLMEAIQ------ISE 94
           D P S +   P+   +L   C   G S +    S E  S  +  T+ EA        ISE
Sbjct: 39  DVPGSDVPQGPSDSQILQGLCASEGPSTSVLPTSAEGPSTFVPPTISEASSASGQPTISE 98

Query: 95  APPTNQA-TAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQA 153
            P T+   T +    +S PPT ++     V+ AA+  ++  +   ++ +    V      
Sbjct: 99  GPGTSVLPTPSEGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSSEEPSTSV-----P 153

Query: 154 HNAKDVPNTQPKAAFKSQNATPKGPNAAYD--FSQAATTGELAANKSEMAFKAQNATTKV 211
             A +VP+T        +  +   P  AY+   +    T +   + S +    +   T V
Sbjct: 154 PTASEVPSTSLPPT-PGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGEGPGTSV 212

Query: 212 GPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVNQAKMATSQADIETD 271
              AT   S S+ A          P  A  +    P   T+ +  + +  AT        
Sbjct: 213 PLAATEGLSTSVQATPDEGPSTSVPPTA-TEGLSTPVPPTRDEGPSTSVPAT-------- 263

Query: 272 PGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTW 331
           PG   P  +    ++DG     + +R   +G  T  +     E  S+  Q      AG  
Sbjct: 264 PG-EGPSTSVLPAASDGQSISLVPTRG--KGSST-SVPPTATEGLSTSVQP----TAGEG 315

Query: 332 RSAPVPVT------TQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQTPPARQSPPARQTP 385
            S  VP T      T  PP A   +    P     P+  +  +    P   +       P
Sbjct: 316 SSTSVPPTPGGGLSTSVPPTATEELSTSVP-----PTPGEGPSTSVLPIPGEGLSTSVPP 370

Query: 386 PAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNPLAWQNPPGWQTPPGWQTP 445
            A        +  + P P    + ++ P     PG  V PNP             G  T 
Sbjct: 371 TASDG----SDTSVPPTPGEGASTLVQPTAPDGPGSSVLPNP-----------GEGPSTL 415

Query: 446 PGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPIPPDWQNLRPSPNLR 505
                  D + P    L    P      + +D   P     A+ PI  +      SPN  
Sbjct: 416 FSSSASVD-RNPSKCSLVLPSPRVTKASVDSDSEGPKG---AEGPIEFEVLRDCESPNSI 471

Query: 506 PSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVY 565
                  S+     +P+D   +++   +L+++L++KD +K PI+ SEM   I++EY + +
Sbjct: 472 SIMGLNTSRVAITLKPQDP--MEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQF 529

Query: 566 PEIIERACFVLEKKFGIQLKEIDKEEHLYILIST--PESLAGILGTTKDTPKLGLLLVIL 623
           PEI+ RA   LE  F  +L+E+D E H YIL++   P    G L  + + PK+GLL++IL
Sbjct: 530 PEILRRAAAHLECIFRFELRELDPEAHTYILLNKLGPVPFEG-LEESPNGPKMGLLMMIL 588

Query: 624 GVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNP 683
           G IF+NGN+A EA +WE L +MG++   R  + G+ ++LL+ EFV Q+YLDYR V +  P
Sbjct: 589 GQIFLNGNQAKEAEIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKP 648

Query: 684 PEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAE 741
            EYEF WG RS+ ET+KMK+L+F+A++  +DP DW  ++ EA +E     DAA A AE
Sbjct: 649 VEYEFFWGPRSHLETTKMKILKFMAKIYNKDPMDWPEKYNEALEE-----DAARAFAE 701



 Score =  147 bits (372), Expect = 3e-35
 Identities = 91/280 (32%), Positives = 145/280 (51%), Gaps = 28/280 (10%)

Query: 469 PPDWPLPTDWPLPPDWIPADWPIPPDWQNLRPSPNLR-----------PSPNSRASQNPG 517
           P DWP   +  L  D   A       WQ L   P+ R           PSP+S  S    
Sbjct: 680 PMDWPEKYNEALEEDAARA---FAEGWQAL---PHFRRPFFEEAAAEVPSPDSEVSSYSS 733

Query: 518 AAQPRD--VALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFV 575
              P     + L+ +A KLV+  +L D TK+PI +  +L  I RE + V+P+++ RA   
Sbjct: 734 KYAPHSWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAART 793

Query: 576 LEKKFGIQLKEIDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGVIFMNGNRAS 634
           L   +G +L  +D   H Y L +  E      +  + + P    L+ +L  IF+ GN A 
Sbjct: 794 LNHVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHAR 853

Query: 635 EAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRS 694
           E+ +W  LR +G++ G +H        ++T  ++ Q+Y+D  RVP+S+P +YEF+WG R+
Sbjct: 854 ESAVWAFLRGLGVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRA 905

Query: 695 YHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALD 734
             ETSKMK LR++A + +++P+DW  Q+ EA ++  +  D
Sbjct: 906 RLETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRAD 945


>gi|73623441 melanoma antigen family B, 10 [Homo sapiens]
          Length = 347

 Score =  174 bits (441), Expect = 3e-43
 Identities = 91/228 (39%), Positives = 139/228 (60%), Gaps = 4/228 (1%)

Query: 527 LQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKE 586
           + E+   LV YL+ K   K PI +++MLR++ +     +P I+ RA   LE  FG+ LKE
Sbjct: 111 VDEKVIILVHYLLYKYQMKEPITKADMLRNVTQMSKSQFPVILSRASEHLELIFGLDLKE 170

Query: 587 IDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKM 645
           ++  +H+Y+L++  +      L      PK GLL+ +LG+IF NGN  +E  +W+    M
Sbjct: 171 VEPNKHIYVLVNKLDLGCDAKLSDETGVPKTGLLMTVLGIIFTNGNCVAEEEVWKVFNTM 230

Query: 646 GLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLR 705
           GL  G+ H + G+ RKLLT + VK+ YL+Y++VPNS+PP Y+FLWG R++ ETSKMKVL 
Sbjct: 231 GLYDGIEHFMFGEPRKLLTKDLVKENYLEYQQVPNSDPPRYQFLWGPRAHAETSKMKVLE 290

Query: 706 FIAEVQKRDPRD---WTAQFMEAADEALDALDAAAAEAEARAEARTRM 750
           F+A+V    P +   W  + ++  +E   A  AA A   A A AR+++
Sbjct: 291 FLAKVNDTAPSEFSNWYTEALQDEEERARARVAAKARVSATAGARSKV 338


>gi|29171714 melanoma antigen family B, 3 [Homo sapiens]
          Length = 346

 Score =  171 bits (434), Expect = 2e-42
 Identities = 91/209 (43%), Positives = 135/209 (64%), Gaps = 1/209 (0%)

Query: 530 RANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDK 589
           + N LV++LM     K PI +++ML+ + + + + +PEI+++A F +E  FG+ LK++D 
Sbjct: 114 KTNMLVQFLMEMYKMKKPIMKADMLKIVQKSHKNCFPEILKKASFNMEVVFGVDLKKVDS 173

Query: 590 EEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLR 648
            +  Y+L+S  +    G +   +  PK GLLL +LGVIFM GN A+E  +WE L KM + 
Sbjct: 174 TKDSYVLVSKMDLPNNGTVTRGRGFPKTGLLLNLLGVIFMKGNCATEEKIWEFLNKMRIY 233

Query: 649 PGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIA 708
            G +H + G+ RKL+T + VK KYL+YR+VPNSNP  YEFLWG R++ ETSKMKVL F A
Sbjct: 234 DGKKHFIFGEPRKLITQDLVKLKYLEYRQVPNSNPARYEFLWGPRAHAETSKMKVLEFWA 293

Query: 709 EVQKRDPRDWTAQFMEAADEALDALDAAA 737
           +V K  P  +   + EA  +  + + AAA
Sbjct: 294 KVNKTVPSAFQFWYEEALRDEEERVQAAA 322


>gi|4505349 necdin [Homo sapiens]
          Length = 321

 Score =  169 bits (429), Expect = 7e-42
 Identities = 101/272 (37%), Positives = 151/272 (55%), Gaps = 12/272 (4%)

Query: 468 LPPDWPL--PTDWPLPPDWIPADWPIPPDWQNLRPSPNL--RPSPNSRASQNPGAAQPRD 523
           +PP   L  P   PL P   P   P PP   N    P    + +   RA Q P AAQP  
Sbjct: 32  VPPSATLAEPQSPPLGPTAAPQAAP-PPQAPNDEGDPKALQQAAEEGRAHQAPSAAQPGP 90

Query: 524 V----ALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKK 579
                A L ++A++L+ Y+++KD  K+ I   +M++D+I  Y      I+ R   +L + 
Sbjct: 91  APPAPAQLVQKAHELMWYVLVKDQKKMIIWFPDMVKDVIGSYKKWCRSILRRTSLILARV 150

Query: 580 FGIQLKEIDKEEHLYILIST--PESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAV 637
           FG+ L+        + L+    PE L  +  + +  P  GLLL+IL +I++ G  A E+ 
Sbjct: 151 FGLHLRLTSLHTMEFALVKALEPEELDRVALSNR-MPMTGLLLMILSLIYVKGRGARESA 209

Query: 638 LWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHE 697
           +W  LR +GLRP  +H   GD+RKL+T EFV+  YL Y+RVP   PPEYEF WG R+  E
Sbjct: 210 VWNVLRILGLRPWKKHSTFGDVRKLITEEFVQMNYLKYQRVPYVEPPEYEFFWGSRASRE 269

Query: 698 TSKMKVLRFIAEVQKRDPRDWTAQFMEAADEA 729
            +KM+++ F+A V K+DP+ W +++ EA +EA
Sbjct: 270 ITKMQIMEFLARVFKKDPQAWPSRYREALEEA 301


>gi|58530863 melanoma antigen family A, 10 [Homo sapiens]
          Length = 369

 Score =  168 bits (426), Expect = 2e-41
 Identities = 108/347 (31%), Positives = 172/347 (49%), Gaps = 16/347 (4%)

Query: 427 PLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPD--W 484
           PLA +      T      P  +           +PL P    P +     + P PP    
Sbjct: 31  PLAVEEDASSSTSTSSSFPSSFPSSSSSSSSSCYPLIPS--TPEEVSADDETPNPPQSAQ 88

Query: 485 IPADWP-----IPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLM 539
           I    P     +P D  +   S     SP++        + PR    + E+   LV++L+
Sbjct: 89  IACSSPSVVASLPLDQSDEGSSSQKEESPSTLQVLPDSESLPRSE--IDEKVTDLVQFLL 146

Query: 540 LKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILI-S 598
            K   K PI ++E+L  +I+ Y D +P +   A   +   FGI +KE+D   H ++L+ S
Sbjct: 147 FKYQMKEPITKAEILESVIKNYEDHFPLLFSEASECMLLVFGIDVKEVDPTGHSFVLVTS 206

Query: 599 TPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGD 658
              +  G+L   +  PK G+L++IL +IF+ G    E V+WEAL  MGL  G+ H + G+
Sbjct: 207 LGLTYDGMLSDVQSMPKTGILILILSIIFIEGYCTPEEVIWEALNMMGLYDGMEHLIYGE 266

Query: 659 LRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDW 718
            RKLLT ++V++ YL+YR+VP S+P  YEFLWG R++ E  KM +L+F+A+V   DPR +
Sbjct: 267 PRKLLTQDWVQENYLEYRQVPGSDPARYEFLWGPRAHAEIRKMSLLKFLAKVNGSDPRSF 326

Query: 719 TAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDD 765
              +    +EAL   +  A +  A  +  T M     + +G +S+ +
Sbjct: 327 PLWY----EEALKDEEERAQDRIATTDDTTAMASASSSATGSFSYPE 369


>gi|10567820 melanoma antigen family A, 10 [Homo sapiens]
          Length = 369

 Score =  168 bits (426), Expect = 2e-41
 Identities = 108/347 (31%), Positives = 172/347 (49%), Gaps = 16/347 (4%)

Query: 427 PLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPD--W 484
           PLA +      T      P  +           +PL P    P +     + P PP    
Sbjct: 31  PLAVEEDASSSTSTSSSFPSSFPSSSSSSSSSCYPLIPS--TPEEVSADDETPNPPQSAQ 88

Query: 485 IPADWP-----IPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLM 539
           I    P     +P D  +   S     SP++        + PR    + E+   LV++L+
Sbjct: 89  IACSSPSVVASLPLDQSDEGSSSQKEESPSTLQVLPDSESLPRSE--IDEKVTDLVQFLL 146

Query: 540 LKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILI-S 598
            K   K PI ++E+L  +I+ Y D +P +   A   +   FGI +KE+D   H ++L+ S
Sbjct: 147 FKYQMKEPITKAEILESVIKNYEDHFPLLFSEASECMLLVFGIDVKEVDPTGHSFVLVTS 206

Query: 599 TPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGD 658
              +  G+L   +  PK G+L++IL +IF+ G    E V+WEAL  MGL  G+ H + G+
Sbjct: 207 LGLTYDGMLSDVQSMPKTGILILILSIIFIEGYCTPEEVIWEALNMMGLYDGMEHLIYGE 266

Query: 659 LRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDW 718
            RKLLT ++V++ YL+YR+VP S+P  YEFLWG R++ E  KM +L+F+A+V   DPR +
Sbjct: 267 PRKLLTQDWVQENYLEYRQVPGSDPARYEFLWGPRAHAEIRKMSLLKFLAKVNGSDPRSF 326

Query: 719 TAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDD 765
              +    +EAL   +  A +  A  +  T M     + +G +S+ +
Sbjct: 327 PLWY----EEALKDEEERAQDRIATTDDTTAMASASSSATGSFSYPE 369


>gi|27734781 melanoma antigen family B, 18 [Homo sapiens]
          Length = 343

 Score =  168 bits (426), Expect = 2e-41
 Identities = 108/288 (37%), Positives = 158/288 (54%), Gaps = 22/288 (7%)

Query: 481 PPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVAL-------------L 527
           P +   A+ P  P+     PS     +P S  S N GA+   + +L             L
Sbjct: 49  PQNLPAAETPSIPEALQGAPSTTNAIAPVS-CSSNEGASSQDEKSLGSSREAEGWKEDPL 107

Query: 528 QERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEI 587
            ++   LV +L+ K  TK PI + +M++ +IR+    + EI++RA   +E   G+ LKE+
Sbjct: 108 NKKVVSLVHFLLQKYETKEPITKGDMIKFVIRKDKCHFNEILKRASEHMELALGVDLKEV 167

Query: 588 DKEEHLYILISTPESLAGILGTTKDT---PKLGLLLVILGVIFMNGNRASEAVLWEALRK 644
           D   H Y   S  +       TT D    PK GLL++ LGVIF+NGNRA E  +WE +  
Sbjct: 168 DPIRHYYAFFSKLDLTYD--ETTSDEEKIPKTGLLMIALGVIFLNGNRAPEEAVWEIMNM 225

Query: 645 MGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVL 704
           MG+    +H L GD RK++T + V+ KYL+Y++VPNS+PP YEFLWG R++ ETSKMKVL
Sbjct: 226 MGVYADRKHFLYGDPRKVMTKDLVQLKYLEYQQVPNSDPPRYEFLWGPRAHAETSKMKVL 285

Query: 705 RFIAEVQKRDPRDWTAQFMEA---ADEALDALDAAAAEAEARAEARTR 749
            F+A++    P  + + + EA    ++   A  AA A   A A AR+R
Sbjct: 286 EFVAKIHDTVPSAFPSCYEEALRDEEQRTQARAAARAHTAAMANARSR 333


>gi|153791873 melanoma antigen family B, 16 [Homo sapiens]
          Length = 324

 Score =  167 bits (424), Expect = 3e-41
 Identities = 93/229 (40%), Positives = 139/229 (60%), Gaps = 7/229 (3%)

Query: 507 SPNSRASQNPGAAQ----PRDVAL--LQERANKLVKYLMLKDYTKVPIKRSEMLRDIIRE 560
           S N     +P +++    PR+V    L ++   LV +++ K   K PI +++ML+ II++
Sbjct: 87  SSNQEEEDSPSSSEDTSDPRNVPADALDQKVAFLVNFMLHKCQMKKPITKADMLKIIIKD 146

Query: 561 YTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLY-ILISTPESLAGILGTTKDTPKLGLL 619
               + EI+ RA   LE  FG+ + E+D   H Y + I    +  G+L   K  PK GLL
Sbjct: 147 DESHFSEILLRASEHLEMIFGLDVVEVDPTTHCYGLFIKLGLTYDGMLSGEKGVPKTGLL 206

Query: 620 LVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVP 679
           +++LGVIFM GNRA+E  +WE L   G+  G +H + G+ R L+T +FVK+KYL+Y++V 
Sbjct: 207 IIVLGVIFMKGNRATEEEVWEVLNLTGVYSGKKHFIFGEPRMLITKDFVKEKYLEYQQVA 266

Query: 680 NSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADE 728
           NS+P  YEFLWG R+  ETSKMKVL F+A+V    P  + +Q+ EA  E
Sbjct: 267 NSDPARYEFLWGPRAKAETSKMKVLEFVAKVHGSYPHSFPSQYAEALKE 315


>gi|61744473 melanoma antigen family A, 11 isoform b [Homo sapiens]
          Length = 400

 Score =  166 bits (421), Expect = 6e-41
 Identities = 90/219 (41%), Positives = 131/219 (59%), Gaps = 3/219 (1%)

Query: 513 SQNPGAAQPRDVA--LLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIE 570
           S +P    P   +  +L ++   LV  L+ K   K  I ++EML  +I+ Y D +PEI  
Sbjct: 177 STSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVKGLITKAEMLGSVIKNYEDYFPEIFR 236

Query: 571 RACFVLEKKFGIQLKEIDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGVIFMN 629
            A   ++  FGI +KE+D   H Y+L+++   S  GI    +  PK GLL+++LGVIFM 
Sbjct: 237 EASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDGIQCNEQSMPKSGLLIIVLGVIFME 296

Query: 630 GNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFL 689
           GN   E V+WE L  MG+  G  H L G+ ++LLT  +V++KYL YR+VP ++P  YEFL
Sbjct: 297 GNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLTQNWVQEKYLVYRQVPGTDPACYEFL 356

Query: 690 WGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADE 728
           WG R++ ETSKMKVL +IA    RDP  + + + +A  E
Sbjct: 357 WGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDALRE 395


>gi|65507078 melanoma antigen family A, 11 isoform a [Homo sapiens]
          Length = 429

 Score =  166 bits (421), Expect = 6e-41
 Identities = 90/219 (41%), Positives = 131/219 (59%), Gaps = 3/219 (1%)

Query: 513 SQNPGAAQPRDVA--LLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIE 570
           S +P    P   +  +L ++   LV  L+ K   K  I ++EML  +I+ Y D +PEI  
Sbjct: 206 STSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVKGLITKAEMLGSVIKNYEDYFPEIFR 265

Query: 571 RACFVLEKKFGIQLKEIDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGVIFMN 629
            A   ++  FGI +KE+D   H Y+L+++   S  GI    +  PK GLL+++LGVIFM 
Sbjct: 266 EASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDGIQCNEQSMPKSGLLIIVLGVIFME 325

Query: 630 GNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFL 689
           GN   E V+WE L  MG+  G  H L G+ ++LLT  +V++KYL YR+VP ++P  YEFL
Sbjct: 326 GNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLTQNWVQEKYLVYRQVPGTDPACYEFL 385

Query: 690 WGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADE 728
           WG R++ ETSKMKVL +IA    RDP  + + + +A  E
Sbjct: 386 WGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDALRE 424


>gi|4505085 melanoma antigen family B, 4 [Homo sapiens]
          Length = 346

 Score =  166 bits (419), Expect = 1e-40
 Identities = 95/256 (37%), Positives = 146/256 (57%), Gaps = 13/256 (5%)

Query: 509 NSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEI 568
           N+ +SQ   + +      L  +   LV++L+ K   K P  ++EML+ I ++Y + +PEI
Sbjct: 91  NASSSQASTSTERSLKDSLTRKTKMLVQFLLYKYKMKEPTTKAEMLKIISKKYKEHFPEI 150

Query: 569 IERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGVIFM 628
             +     E  FG+ LKE++   H YIL+S      G   +    P+ GLL+ +L VIF+
Sbjct: 151 FRKVSQRTELVFGLALKEVNPTTHSYILVSMLGPNDGNQSSAWTLPRNGLLMPLLSVIFL 210

Query: 629 NGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEF 688
           NGN A E  +WE L  +G+  G RH + G+ RKL+T + V++KYL+Y++VPNS+PP Y+F
Sbjct: 211 NGNCAREEEIWEFLNMLGIYDGKRHLIFGEPRKLITQDLVQEKYLEYQQVPNSDPPRYQF 270

Query: 689 LWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAEART 748
           LWG R++ ETSKMKVL F+A+V    P ++   + E           A  + E RA AR 
Sbjct: 271 LWGPRAHAETSKMKVLEFLAKVNDTTPNNFPLLYEE-----------ALRDEEERAGARP 319

Query: 749 RMGI--GDEAVSGPWS 762
           R+    G  A++  +S
Sbjct: 320 RVAARRGTTAMTSAYS 335


>gi|19923308 melanoma antigen family A, 8 [Homo sapiens]
          Length = 318

 Score =  166 bits (419), Expect = 1e-40
 Identities = 86/203 (42%), Positives = 126/203 (62%), Gaps = 1/203 (0%)

Query: 527 LQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKE 586
           L E+  +LV++L+ K   K P+ ++EML  +I+ Y + +P+I  +A   ++  FGI +KE
Sbjct: 112 LDEKVAELVRFLLRKYQIKEPVTKAEMLESVIKNYKNHFPDIFSKASECMQVIFGIDVKE 171

Query: 587 IDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKM 645
           +D   H YIL++    S  G+LG  + TPK GLL+++LG+I M G+RA E  +WEAL  M
Sbjct: 172 VDPAGHSYILVTCLGLSYDGLLGDDQSTPKTGLLIIVLGMILMEGSRAPEEAIWEALSVM 231

Query: 646 GLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLR 705
           GL  G  H +   LRKLLT E+V++ YL+YR+ P S+P  YEFLWG R+  ETS +KVL 
Sbjct: 232 GLYDGREHSVYWKLRKLLTQEWVQENYLEYRQAPGSDPVRYEFLWGPRALAETSYVKVLE 291

Query: 706 FIAEVQKRDPRDWTAQFMEAADE 728
            +  V  R    + +   EA  E
Sbjct: 292 HVVRVNARVRISYPSLHEEALGE 314


>gi|169216977 PREDICTED: melanoma antigen family B, 17 [Homo
           sapiens]
          Length = 457

 Score =  164 bits (414), Expect = 4e-40
 Identities = 96/244 (39%), Positives = 144/244 (59%), Gaps = 6/244 (2%)

Query: 507 SPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYP 566
           SPNS    +   +  RD  LL  +  +LV++L+ K   K PI R  ML+ I R+Y   +P
Sbjct: 212 SPNSFHGPSSSESTGRD--LLNTKTGELVQFLLNKYIRKEPITREAMLKVINRKYKQHFP 269

Query: 567 EIIERACFVLEKKFGIQLKEIDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGV 625
           EI+ R+   +E  FG+ LKE+D     Y+L+   +    G L      P  GLL+V+L  
Sbjct: 270 EILRRSTENVEVVFGLYLKEMDPSRQSYVLVGKLDFPNQGSLSDGGGFPLSGLLMVLLST 329

Query: 626 IFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPE 685
           IFM+GNRA+E  +WE L  +G+  G +H + G+ ++L+T + V++ YL+Y++VP+S+PP 
Sbjct: 330 IFMHGNRATEEEMWECLNALGMYKGRKHFIYGEPQELVTKDLVREGYLEYQQVPSSDPPR 389

Query: 686 YEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAE 745
           YEFLWG R+  ETSKMKVL F+A++       + +++ EA  E     + A A A AR  
Sbjct: 390 YEFLWGPRARAETSKMKVLEFVAKLNDTVASTYKSRYEEALRE---EEEQARARAVARDS 446

Query: 746 ARTR 749
           AR R
Sbjct: 447 ARAR 450


>gi|169216191 PREDICTED: melanoma antigen family B, 17 [Homo
           sapiens]
          Length = 457

 Score =  164 bits (414), Expect = 4e-40
 Identities = 96/244 (39%), Positives = 144/244 (59%), Gaps = 6/244 (2%)

Query: 507 SPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYP 566
           SPNS    +   +  RD  LL  +  +LV++L+ K   K PI R  ML+ I R+Y   +P
Sbjct: 212 SPNSFHGPSSSESTGRD--LLNTKTGELVQFLLNKYIRKEPITREAMLKVINRKYKQHFP 269

Query: 567 EIIERACFVLEKKFGIQLKEIDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGV 625
           EI+ R+   +E  FG+ LKE+D     Y+L+   +    G L      P  GLL+V+L  
Sbjct: 270 EILRRSTENVEVVFGLYLKEMDPSRQSYVLVGKLDFPNQGSLSDGGGFPLSGLLMVLLST 329

Query: 626 IFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPE 685
           IFM+GNRA+E  +WE L  +G+  G +H + G+ ++L+T + V++ YL+Y++VP+S+PP 
Sbjct: 330 IFMHGNRATEEEMWECLNALGMYKGRKHFIYGEPQELVTKDLVREGYLEYQQVPSSDPPR 389

Query: 686 YEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAE 745
           YEFLWG R+  ETSKMKVL F+A++       + +++ EA  E     + A A A AR  
Sbjct: 390 YEFLWGPRARAETSKMKVLEFVAKLNDTVASTYKSRYEEALRE---EEEQARARAVARDS 446

Query: 746 ARTR 749
           AR R
Sbjct: 447 ARAR 450


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,770,370
Number of Sequences: 37866
Number of extensions: 2612159
Number of successful extensions: 18343
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 240
Number of HSP's successfully gapped in prelim test: 492
Number of HSP's that attempted gapping in prelim test: 9091
Number of HSP's gapped (non-prelim): 6523
length of query: 834
length of database: 18,247,518
effective HSP length: 111
effective length of query: 723
effective length of database: 14,044,392
effective search space: 10154095416
effective search space used: 10154095416
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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