Guide to the Human Genome
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Search of human proteins with 52632377

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|52632377 melanoma antigen family D, 1 isoform b [Homo
sapiens]
         (778 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|52632379 melanoma antigen family D, 1 isoform b [Homo sapiens]    1631   0.0  
gi|52632377 melanoma antigen family D, 1 isoform b [Homo sapiens]    1631   0.0  
gi|52632381 melanoma antigen family D, 1 isoform a [Homo sapiens]    1600   0.0  
gi|29337296 melanoma antigen family D, 4B isoform 2 [Homo sapiens]    452   e-127
gi|29337294 melanoma antigen family D, 4B isoform 1 [Homo sapiens]    452   e-127
gi|29337292 melanoma antigen family D, 4B isoform 1 [Homo sapiens]    452   e-127
gi|149274614 melanoma antigen family D, 4 [Homo sapiens]              452   e-127
gi|89276766 trophinin isoform 5 [Homo sapiens]                        404   e-112
gi|29171705 melanoma antigen family D, 2 [Homo sapiens]               370   e-102
gi|19387846 melanoma antigen family D, 2 [Homo sapiens]               370   e-102
gi|41350320 melanoma antigen family D, 2 [Homo sapiens]               370   e-102
gi|29540551 trophinin isoform 2 [Homo sapiens]                        343   3e-94
gi|29540541 trophinin isoform 2 [Homo sapiens]                        343   3e-94
gi|148746206 MAGE-like protein 2 [Homo sapiens]                       212   1e-54
gi|20162572 necdin-like 2 [Homo sapiens]                              203   4e-52
gi|29826296 melanoma antigen family F, 1 [Homo sapiens]               200   4e-51
gi|20143482 melanoma antigen family E, 1 [Homo sapiens]               188   1e-47
gi|73623441 melanoma antigen family B, 10 [Homo sapiens]              174   3e-43
gi|29171714 melanoma antigen family B, 3 [Homo sapiens]               171   2e-42
gi|4505349 necdin [Homo sapiens]                                      169   7e-42
gi|58530863 melanoma antigen family A, 10 [Homo sapiens]              168   2e-41
gi|10567820 melanoma antigen family A, 10 [Homo sapiens]              168   2e-41
gi|27734781 melanoma antigen family B, 18 [Homo sapiens]              168   2e-41
gi|153791873 melanoma antigen family B, 16 [Homo sapiens]             167   3e-41
gi|61744473 melanoma antigen family A, 11 isoform b [Homo sapiens]    166   6e-41
gi|65507078 melanoma antigen family A, 11 isoform a [Homo sapiens]    166   6e-41
gi|4505085 melanoma antigen family B, 4 [Homo sapiens]                166   1e-40
gi|19923308 melanoma antigen family A, 8 [Homo sapiens]               166   1e-40
gi|169216977 PREDICTED: melanoma antigen family B, 17 [Homo sapi...   164   4e-40
gi|169216191 PREDICTED: melanoma antigen family B, 17 [Homo sapi...   164   4e-40

>gi|52632379 melanoma antigen family D, 1 isoform b [Homo sapiens]
          Length = 778

 Score = 1631 bits (4223), Expect = 0.0
 Identities = 778/778 (100%), Positives = 778/778 (100%)

Query: 1   MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN 60
           MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN
Sbjct: 1   MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN 60

Query: 61  EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK 120
           EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK
Sbjct: 61  EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK 120

Query: 121 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP 180
           GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP
Sbjct: 121 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP 180

Query: 181 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES 240
           FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES
Sbjct: 181 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES 240

Query: 241 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPL 300
           RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPL
Sbjct: 241 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPL 300

Query: 301 AWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPI 360
           AWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPI
Sbjct: 301 AWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPI 360

Query: 361 VWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPT 420
           VWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPT
Sbjct: 361 VWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPT 420

Query: 421 DWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVK 480
           DWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVK
Sbjct: 421 DWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVK 480

Query: 481 YLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYIL 540
           YLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYIL
Sbjct: 481 YLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYIL 540

Query: 541 ISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLL 600
           ISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLL
Sbjct: 541 ISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLL 600

Query: 601 GDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPR 660
           GDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPR
Sbjct: 601 GDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPR 660

Query: 661 DWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEE 720
           DWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEE
Sbjct: 661 DWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEE 720

Query: 721 GDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE 778
           GDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE
Sbjct: 721 GDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE 778


>gi|52632377 melanoma antigen family D, 1 isoform b [Homo sapiens]
          Length = 778

 Score = 1631 bits (4223), Expect = 0.0
 Identities = 778/778 (100%), Positives = 778/778 (100%)

Query: 1   MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN 60
           MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN
Sbjct: 1   MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN 60

Query: 61  EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK 120
           EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK
Sbjct: 61  EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK 120

Query: 121 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP 180
           GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP
Sbjct: 121 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP 180

Query: 181 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES 240
           FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES
Sbjct: 181 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES 240

Query: 241 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPL 300
           RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPL
Sbjct: 241 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPL 300

Query: 301 AWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPI 360
           AWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPI
Sbjct: 301 AWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPI 360

Query: 361 VWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPT 420
           VWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPT
Sbjct: 361 VWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPT 420

Query: 421 DWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVK 480
           DWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVK
Sbjct: 421 DWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVK 480

Query: 481 YLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYIL 540
           YLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYIL
Sbjct: 481 YLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYIL 540

Query: 541 ISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLL 600
           ISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLL
Sbjct: 541 ISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLL 600

Query: 601 GDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPR 660
           GDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPR
Sbjct: 601 GDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPR 660

Query: 661 DWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEE 720
           DWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEE
Sbjct: 661 DWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEE 720

Query: 721 GDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE 778
           GDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE
Sbjct: 721 GDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE 778


>gi|52632381 melanoma antigen family D, 1 isoform a [Homo sapiens]
          Length = 834

 Score = 1600 bits (4143), Expect = 0.0
 Identities = 763/763 (100%), Positives = 763/763 (100%)

Query: 16  AEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPK 75
           AEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPK
Sbjct: 72  AEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPK 131

Query: 76  SAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTG 135
           SAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTG
Sbjct: 132 SAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTG 191

Query: 136 ELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADT 195
           ELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADT
Sbjct: 192 ELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADT 251

Query: 196 QTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNL 255
           QTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNL
Sbjct: 252 QTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNL 311

Query: 256 NVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQ 315
           NVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQ
Sbjct: 312 NVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQ 371

Query: 316 TPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNPLAWQ 375
           TPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNPLAWQ
Sbjct: 372 TPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNPLAWQ 431

Query: 376 NPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPI 435
           NPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPI
Sbjct: 432 NPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPI 491

Query: 436 PPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRS 495
           PPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRS
Sbjct: 492 PPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRS 551

Query: 496 EMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTK 555
           EMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTK
Sbjct: 552 EMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTK 611

Query: 556 DTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQK 615
           DTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQK
Sbjct: 612 DTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQK 671

Query: 616 YLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALD 675
           YLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALD
Sbjct: 672 YLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALD 731

Query: 676 ALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFW 735
           ALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFW
Sbjct: 732 ALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFW 791

Query: 736 ARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE 778
           ARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE
Sbjct: 792 ARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE 834


>gi|29337296 melanoma antigen family D, 4B isoform 2 [Homo sapiens]
          Length = 739

 Score =  452 bits (1163), Expect = e-127
 Identities = 230/372 (61%), Positives = 272/372 (73%), Gaps = 28/372 (7%)

Query: 435 IPPDWQNLRPSPNLRPS-----PNSRASQNPG----AAQPRDVALLQERANKLVKYLMLK 485
           +PP W+  +PS  +R       P +  SQ P        PR+V LLQERANKLVKYLM+K
Sbjct: 368 VPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPRNVTLLQERANKLVKYLMIK 427

Query: 486 DYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPE 545
           DY K+PIKR++ML+D+IREY + +PEIIERA + LEKKFGI LKEIDKEEHLYIL+ T +
Sbjct: 428 DYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRD 487

Query: 546 SLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRK 605
           S A +LG TKDTP+L LLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHP LGDLRK
Sbjct: 488 SSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRK 547

Query: 606 LLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQ 665
           L+T +FVKQKYL+Y+++PNSNPPEYEFLWGLR+ HETSKM+VLRFIA+ Q RDPR+W A 
Sbjct: 548 LITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAH 607

Query: 666 FMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGD 725
           F+EA D+A   +D   AE  ARA+ R +M IGDEA+ G WSWDDI+ ELLTWDE+GDFGD
Sbjct: 608 FLEAVDDAFKTMDVDMAEEHARAQMRAQMNIGDEALIGRWSWDDIQVELLTWDEDGDFGD 667

Query: 726 PWSRIPFTFWARYHQ-----NARSRFPQTFAGPIIGPGGTASANF--------------A 766
            W+RIPF FWARYHQ     N  +R     AG   G  G AS +               A
Sbjct: 668 AWARIPFAFWARYHQYILNSNRANRRATWRAGVSSGTNGGASTSVLDGPSTSSTIRTRNA 727

Query: 767 ANFGAIGFFWVE 778
           A  GA  F W++
Sbjct: 728 ARAGASFFSWIQ 739



 Score =  101 bits (251), Expect = 3e-21
 Identities = 81/261 (31%), Positives = 125/261 (47%), Gaps = 27/261 (10%)

Query: 37  SEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQ 96
           +EA         ASPQ+SQ    ++MA  +  A +A+ ++    Q A T+GP+    FSQ
Sbjct: 154 AEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATSAQSQTGSPAQEAATEGPSSACAFSQ 213

Query: 97  AHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVG 156
           A  A++V   +P  AF        G N  +DF+Q A    +A  + +    AQ A T+ G
Sbjct: 214 APCAREVDANRPSTAF-------LGQNDVFDFTQPAGVSGMAFPRPKRPAPAQEAATE-G 265

Query: 157 PNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVN-QAKMATSQADIETD 215
           P+A     Q+    ++A +RPK        TTK+  A  +T+ V  Q  +A + A  +  
Sbjct: 266 PSAASGVPQTGPGREVAATRPK--------TTKSGKALAKTRWVEPQNVVAAAAAKAKMA 317

Query: 216 PGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTW 275
             I EP+GA A T+       + E    + GKRT+K  +L+ E  SS ++R  P    TW
Sbjct: 318 TSIPEPEGAAAATA-----QHSAEPWARMGGKRTKKSKHLDDEYESSEEERETPAVPPTW 372

Query: 276 RSAPVPVTTQ-----NPPGAP 291
           R++   +T +      PP AP
Sbjct: 373 RASQPSLTVRAQLAPRPPMAP 393


>gi|29337294 melanoma antigen family D, 4B isoform 1 [Homo sapiens]
          Length = 741

 Score =  452 bits (1163), Expect = e-127
 Identities = 230/372 (61%), Positives = 272/372 (73%), Gaps = 28/372 (7%)

Query: 435 IPPDWQNLRPSPNLRPS-----PNSRASQNPG----AAQPRDVALLQERANKLVKYLMLK 485
           +PP W+  +PS  +R       P +  SQ P        PR+V LLQERANKLVKYLM+K
Sbjct: 368 VPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPRNVTLLQERANKLVKYLMIK 427

Query: 486 DYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPE 545
           DY K+PIKR++ML+D+IREY + +PEIIERA + LEKKFGI LKEIDKEEHLYIL+ T +
Sbjct: 428 DYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRD 487

Query: 546 SLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRK 605
           S A +LG TKDTP+L LLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHP LGDLRK
Sbjct: 488 SSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRK 547

Query: 606 LLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQ 665
           L+T +FVKQKYL+Y+++PNSNPPEYEFLWGLR+ HETSKM+VLRFIA+ Q RDPR+W A 
Sbjct: 548 LITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAH 607

Query: 666 FMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGD 725
           F+EA D+A   +D   AE  ARA+ R +M IGDEA+ G WSWDDI+ ELLTWDE+GDFGD
Sbjct: 608 FLEAVDDAFKTMDVDMAEEHARAQMRAQMNIGDEALIGRWSWDDIQVELLTWDEDGDFGD 667

Query: 726 PWSRIPFTFWARYHQ-----NARSRFPQTFAGPIIGPGGTASANF--------------A 766
            W+RIPF FWARYHQ     N  +R     AG   G  G AS +               A
Sbjct: 668 AWARIPFAFWARYHQYILNSNRANRRATWRAGVSSGTNGGASTSVLDGPSTSSTIRTRNA 727

Query: 767 ANFGAIGFFWVE 778
           A  GA  F W++
Sbjct: 728 ARAGASFFSWIQ 739



 Score =  101 bits (251), Expect = 3e-21
 Identities = 81/261 (31%), Positives = 125/261 (47%), Gaps = 27/261 (10%)

Query: 37  SEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQ 96
           +EA         ASPQ+SQ    ++MA  +  A +A+ ++    Q A T+GP+    FSQ
Sbjct: 154 AEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATSAQSQTGSPAQEAATEGPSSACAFSQ 213

Query: 97  AHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVG 156
           A  A++V   +P  AF        G N  +DF+Q A    +A  + +    AQ A T+ G
Sbjct: 214 APCAREVDANRPSTAF-------LGQNDVFDFTQPAGVSGMAFPRPKRPAPAQEAATE-G 265

Query: 157 PNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVN-QAKMATSQADIETD 215
           P+A     Q+    ++A +RPK        TTK+  A  +T+ V  Q  +A + A  +  
Sbjct: 266 PSAASGVPQTGPGREVAATRPK--------TTKSGKALAKTRWVEPQNVVAAAAAKAKMA 317

Query: 216 PGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTW 275
             I EP+GA A T+       + E    + GKRT+K  +L+ E  SS ++R  P    TW
Sbjct: 318 TSIPEPEGAAAATA-----QHSAEPWARMGGKRTKKSKHLDDEYESSEEERETPAVPPTW 372

Query: 276 RSAPVPVTTQ-----NPPGAP 291
           R++   +T +      PP AP
Sbjct: 373 RASQPSLTVRAQLAPRPPMAP 393


>gi|29337292 melanoma antigen family D, 4B isoform 1 [Homo sapiens]
          Length = 741

 Score =  452 bits (1163), Expect = e-127
 Identities = 230/372 (61%), Positives = 272/372 (73%), Gaps = 28/372 (7%)

Query: 435 IPPDWQNLRPSPNLRPS-----PNSRASQNPG----AAQPRDVALLQERANKLVKYLMLK 485
           +PP W+  +PS  +R       P +  SQ P        PR+V LLQERANKLVKYLM+K
Sbjct: 368 VPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPRNVTLLQERANKLVKYLMIK 427

Query: 486 DYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPE 545
           DY K+PIKR++ML+D+IREY + +PEIIERA + LEKKFGI LKEIDKEEHLYIL+ T +
Sbjct: 428 DYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRD 487

Query: 546 SLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRK 605
           S A +LG TKDTP+L LLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHP LGDLRK
Sbjct: 488 SSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRK 547

Query: 606 LLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQ 665
           L+T +FVKQKYL+Y+++PNSNPPEYEFLWGLR+ HETSKM+VLRFIA+ Q RDPR+W A 
Sbjct: 548 LITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAH 607

Query: 666 FMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGD 725
           F+EA D+A   +D   AE  ARA+ R +M IGDEA+ G WSWDDI+ ELLTWDE+GDFGD
Sbjct: 608 FLEAVDDAFKTMDVDMAEEHARAQMRAQMNIGDEALIGRWSWDDIQVELLTWDEDGDFGD 667

Query: 726 PWSRIPFTFWARYHQ-----NARSRFPQTFAGPIIGPGGTASANF--------------A 766
            W+RIPF FWARYHQ     N  +R     AG   G  G AS +               A
Sbjct: 668 AWARIPFAFWARYHQYILNSNRANRRATWRAGVSSGTNGGASTSVLDGPSTSSTIRTRNA 727

Query: 767 ANFGAIGFFWVE 778
           A  GA  F W++
Sbjct: 728 ARAGASFFSWIQ 739



 Score =  101 bits (251), Expect = 3e-21
 Identities = 81/261 (31%), Positives = 125/261 (47%), Gaps = 27/261 (10%)

Query: 37  SEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQ 96
           +EA         ASPQ+SQ    ++MA  +  A +A+ ++    Q A T+GP+    FSQ
Sbjct: 154 AEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATSAQSQTGSPAQEAATEGPSSACAFSQ 213

Query: 97  AHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVG 156
           A  A++V   +P  AF        G N  +DF+Q A    +A  + +    AQ A T+ G
Sbjct: 214 APCAREVDANRPSTAF-------LGQNDVFDFTQPAGVSGMAFPRPKRPAPAQEAATE-G 265

Query: 157 PNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVN-QAKMATSQADIETD 215
           P+A     Q+    ++A +RPK        TTK+  A  +T+ V  Q  +A + A  +  
Sbjct: 266 PSAASGVPQTGPGREVAATRPK--------TTKSGKALAKTRWVEPQNVVAAAAAKAKMA 317

Query: 216 PGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTW 275
             I EP+GA A T+       + E    + GKRT+K  +L+ E  SS ++R  P    TW
Sbjct: 318 TSIPEPEGAAAATA-----QHSAEPWARMGGKRTKKSKHLDDEYESSEEERETPAVPPTW 372

Query: 276 RSAPVPVTTQ-----NPPGAP 291
           R++   +T +      PP AP
Sbjct: 373 RASQPSLTVRAQLAPRPPMAP 393


>gi|149274614 melanoma antigen family D, 4 [Homo sapiens]
          Length = 739

 Score =  452 bits (1163), Expect = e-127
 Identities = 230/372 (61%), Positives = 272/372 (73%), Gaps = 28/372 (7%)

Query: 435 IPPDWQNLRPSPNLRPS-----PNSRASQNPG----AAQPRDVALLQERANKLVKYLMLK 485
           +PP W+  +PS  +R       P +  SQ P        PR+V LLQERANKLVKYLM+K
Sbjct: 368 VPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPRNVTLLQERANKLVKYLMIK 427

Query: 486 DYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPE 545
           DY K+PIKR++ML+D+IREY + +PEIIERA + LEKKFGI LKEIDKEEHLYIL+ T +
Sbjct: 428 DYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRD 487

Query: 546 SLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRK 605
           S A +LG TKDTP+L LLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHP LGDLRK
Sbjct: 488 SSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRK 547

Query: 606 LLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQ 665
           L+T +FVKQKYL+Y+++PNSNPPEYEFLWGLR+ HETSKM+VLRFIA+ Q RDPR+W A 
Sbjct: 548 LITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAH 607

Query: 666 FMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGD 725
           F+EA D+A   +D   AE  ARA+ R +M IGDEA+ G WSWDDI+ ELLTWDE+GDFGD
Sbjct: 608 FLEAVDDAFKTMDVDMAEEHARAQMRAQMNIGDEALIGRWSWDDIQVELLTWDEDGDFGD 667

Query: 726 PWSRIPFTFWARYHQ-----NARSRFPQTFAGPIIGPGGTASANF--------------A 766
            W+RIPF FWARYHQ     N  +R     AG   G  G AS +               A
Sbjct: 668 AWARIPFAFWARYHQYILNSNRANRRATWRAGVSSGTNGGASTSVLDGPSTSSTIRTRNA 727

Query: 767 ANFGAIGFFWVE 778
           A  GA  F W++
Sbjct: 728 ARAGASFFSWIQ 739



 Score =  101 bits (251), Expect = 3e-21
 Identities = 81/261 (31%), Positives = 125/261 (47%), Gaps = 27/261 (10%)

Query: 37  SEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQ 96
           +EA         ASPQ+SQ    ++MA  +  A +A+ ++    Q A T+GP+    FSQ
Sbjct: 154 AEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATSAQSQTGSPAQEAATEGPSSACAFSQ 213

Query: 97  AHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVG 156
           A  A++V   +P  AF        G N  +DF+Q A    +A  + +    AQ A T+ G
Sbjct: 214 APCAREVDANRPSTAF-------LGQNDVFDFTQPAGVSGMAFPRPKRPAPAQEAATE-G 265

Query: 157 PNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVN-QAKMATSQADIETD 215
           P+A     Q+    ++A +RPK        TTK+  A  +T+ V  Q  +A + A  +  
Sbjct: 266 PSAASGVPQTGPGREVAATRPK--------TTKSGKALAKTRWVEPQNVVAAAAAKAKMA 317

Query: 216 PGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTW 275
             I EP+GA A T+       + E    + GKRT+K  +L+ E  SS ++R  P    TW
Sbjct: 318 TSIPEPEGAAAATA-----QHSAEPWARMGGKRTKKSKHLDDEYESSEEERETPAVPPTW 372

Query: 276 RSAPVPVTTQ-----NPPGAP 291
           R++   +T +      PP AP
Sbjct: 373 RASQPSLTVRAQLAPRPPMAP 393


>gi|89276766 trophinin isoform 5 [Homo sapiens]
          Length = 1431

 Score =  404 bits (1038), Expect = e-112
 Identities = 194/280 (69%), Positives = 230/280 (82%)

Query: 463 AQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEK 522
           A PRDVA+LQERANKLVKYL++KD TK+PIKRS+MLRD+I+EY + +PEIIERA + LEK
Sbjct: 436 APPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEK 495

Query: 523 KFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVL 582
            F + LKEIDK+  LYILIST ES AGILGTTKDTPKLGLL+VIL VIFMNGN+ASEAV+
Sbjct: 496 MFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVI 555

Query: 583 WEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHET 642
           WE LRK+GLRPGVRH L G++RKL+T EFVKQKYL+Y+RVPNS PPEYEF WGLRSYHET
Sbjct: 556 WEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHET 615

Query: 643 SKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVS 702
           SKMKVL+F   VQK+DP+DW  Q+ EA +  + A   A AEAEARAEAR +MGIG+EAV+
Sbjct: 616 SKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEARAQMGIGEEAVA 675

Query: 703 GPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNA 742
           GPW+WDD++ + LT +E GD    WSR  F   AR  +NA
Sbjct: 676 GPWNWDDMDIDCLTREELGDDAQAWSRFSFEIEARAQENA 715



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 72/258 (27%), Positives = 106/258 (41%), Gaps = 48/258 (18%)

Query: 36  ISEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFS 95
           I+ A   + A  A    ++Q    NE A I  +AA+ R K A K +    K  N   +  
Sbjct: 216 IASATEVSLAATATHTATTQGQITNETASIHTTAASIRTKKASKARKTIAKVINTDTEHI 275

Query: 96  QAHNAKDVPNTQPKAAF--------KSQNATPKGPNAAYDFSQAATTGELAANKSEMAFK 147
           +A N  D    Q +A+         K + A  +GPN+  + S+A    ++  N+      
Sbjct: 276 EALNVTDAATRQIEASVVAIRPKKSKGKKAASRGPNSVSEISEAPLATQIVTNQ------ 329

Query: 148 AQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVNQ---AK 204
           A  AT +V                      K   +A    TKA   ++QT N +Q   AK
Sbjct: 330 ALAATLRV----------------------KRGSRARKAATKARATESQTPNADQGAQAK 367

Query: 205 MATSQADIETDPGISEPDGATAQTSADGSQAQ-NLESRTIIRGKRTRKINNLNVEENSSG 263
           +A++Q ++     +     A  Q  AD   AQ +LE  T  RGKR RK  +LN +E S  
Sbjct: 368 IASAQTNVSA---LETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKHLNGDERSGS 424

Query: 264 DQRRAPLAAGTWRSAPVP 281
           + RR P     W   P P
Sbjct: 425 NYRRIP-----WGRRPAP 437


>gi|29171705 melanoma antigen family D, 2 [Homo sapiens]
          Length = 606

 Score =  370 bits (951), Expect = e-102
 Identities = 198/327 (60%), Positives = 237/327 (72%), Gaps = 16/327 (4%)

Query: 449 RPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDV 508
           R +   ++SQ P A  PRDVALLQ RAN LVKYL+ KD TK+PIKRS+ML+DII+EYTDV
Sbjct: 257 RRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDV 316

Query: 509 YPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESL-AGILGTTKDTPKLGLLLVIL 567
           YPEIIERA + LEK FGIQLKEIDK +HLYIL+ST E   AGILGTTKD+PKLGLL+V+L
Sbjct: 317 YPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLL 376

Query: 568 GVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNP 627
            +IFMNGNR+SEAV+WE LRK+GLRPG+ H L GD++KL+T EFVKQKYLDY RVPNSNP
Sbjct: 377 SIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNP 436

Query: 628 PEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEAR 687
           PEYEF WGLRSY+ETSKMKVL+F  +VQK+DP++W AQ+ EA +  L A   AAAEA+AR
Sbjct: 437 PEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKAR 496

Query: 688 AEARTRMGI--GDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNAR-S 744
           AE R RMGI  G E  +GP +WD           E D G PW++      A     A+ S
Sbjct: 497 AEIRARMGIGLGSENAAGPCNWD-----------EADIG-PWAKARIQAGAEAKAKAQES 544

Query: 745 RFPQTFAGPIIGPGGTASANFAANFGA 771
               T A        +ASA+ +  F A
Sbjct: 545 GSASTGASTSTNNSASASASTSGGFSA 571



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 85/328 (25%), Positives = 129/328 (39%), Gaps = 77/328 (23%)

Query: 1   MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN 60
           M+   + GAGL  FQAEAS +DS+ +MQTL+   Q  E P T +A+ A            
Sbjct: 1   MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSE------- 53

Query: 61  EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK 120
              D++VS A+   K+                + S+   A++ P TQ             
Sbjct: 54  ---DVKVSKASGVSKAT---------------EVSKTPEAREAPATQ------------- 82

Query: 121 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP 180
               A   +Q   T  LAA    +A     A TK             NA+  A + P T 
Sbjct: 83  ----ASSTTQLTDTQVLAAENKSLA-----ADTK-----------KQNADPQAVTMPATE 122

Query: 181 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES 240
            K       +  ADT+   VN     T  A  +      EP+ A AQ+       +N ++
Sbjct: 123 TK-----KVSHVADTK---VNTKAQETEAAPSQAPADEPEPESAAAQSQ------ENQDT 168

Query: 241 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWR-SAPVPVTTQNPPGAPPNVLWQTP 299
           R  ++ K+ RK+ +L+ EE+ S DQ +A    G  R S  +  +        P   W   
Sbjct: 169 RPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARR 228

Query: 300 LAWQNPSGWQNQTARQTPPARQSPPARQ 327
            +    + W    AR+   + +SP AR+
Sbjct: 229 ASRTRLAAW----ARRALLSLRSPKARR 252


>gi|19387846 melanoma antigen family D, 2 [Homo sapiens]
          Length = 606

 Score =  370 bits (951), Expect = e-102
 Identities = 198/327 (60%), Positives = 237/327 (72%), Gaps = 16/327 (4%)

Query: 449 RPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDV 508
           R +   ++SQ P A  PRDVALLQ RAN LVKYL+ KD TK+PIKRS+ML+DII+EYTDV
Sbjct: 257 RRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDV 316

Query: 509 YPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESL-AGILGTTKDTPKLGLLLVIL 567
           YPEIIERA + LEK FGIQLKEIDK +HLYIL+ST E   AGILGTTKD+PKLGLL+V+L
Sbjct: 317 YPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLL 376

Query: 568 GVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNP 627
            +IFMNGNR+SEAV+WE LRK+GLRPG+ H L GD++KL+T EFVKQKYLDY RVPNSNP
Sbjct: 377 SIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNP 436

Query: 628 PEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEAR 687
           PEYEF WGLRSY+ETSKMKVL+F  +VQK+DP++W AQ+ EA +  L A   AAAEA+AR
Sbjct: 437 PEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKAR 496

Query: 688 AEARTRMGI--GDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNAR-S 744
           AE R RMGI  G E  +GP +WD           E D G PW++      A     A+ S
Sbjct: 497 AEIRARMGIGLGSENAAGPCNWD-----------EADIG-PWAKARIQAGAEAKAKAQES 544

Query: 745 RFPQTFAGPIIGPGGTASANFAANFGA 771
               T A        +ASA+ +  F A
Sbjct: 545 GSASTGASTSTNNSASASASTSGGFSA 571



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 85/328 (25%), Positives = 129/328 (39%), Gaps = 77/328 (23%)

Query: 1   MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN 60
           M+   + GAGL  FQAEAS +DS+ +MQTL+   Q  E P T +A+ A            
Sbjct: 1   MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSE------- 53

Query: 61  EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK 120
              D++VS A+   K+                + S+   A++ P TQ             
Sbjct: 54  ---DVKVSKASGVSKAT---------------EVSKTPEAREAPATQ------------- 82

Query: 121 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP 180
               A   +Q   T  LAA    +A     A TK             NA+  A + P T 
Sbjct: 83  ----ASSTTQLTDTQVLAAENKSLA-----ADTK-----------KQNADPQAVTMPATE 122

Query: 181 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES 240
            K       +  ADT+   VN     T  A  +      EP+ A AQ+       +N ++
Sbjct: 123 TK-----KVSHVADTK---VNTKAQETEAAPSQAPADEPEPESAAAQSQ------ENQDT 168

Query: 241 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWR-SAPVPVTTQNPPGAPPNVLWQTP 299
           R  ++ K+ RK+ +L+ EE+ S DQ +A    G  R S  +  +        P   W   
Sbjct: 169 RPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARR 228

Query: 300 LAWQNPSGWQNQTARQTPPARQSPPARQ 327
            +    + W    AR+   + +SP AR+
Sbjct: 229 ASRTRLAAW----ARRALLSLRSPKARR 252


>gi|41350320 melanoma antigen family D, 2 [Homo sapiens]
          Length = 606

 Score =  370 bits (951), Expect = e-102
 Identities = 198/327 (60%), Positives = 237/327 (72%), Gaps = 16/327 (4%)

Query: 449 RPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDV 508
           R +   ++SQ P A  PRDVALLQ RAN LVKYL+ KD TK+PIKRS+ML+DII+EYTDV
Sbjct: 257 RRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDV 316

Query: 509 YPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESL-AGILGTTKDTPKLGLLLVIL 567
           YPEIIERA + LEK FGIQLKEIDK +HLYIL+ST E   AGILGTTKD+PKLGLL+V+L
Sbjct: 317 YPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLL 376

Query: 568 GVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNP 627
            +IFMNGNR+SEAV+WE LRK+GLRPG+ H L GD++KL+T EFVKQKYLDY RVPNSNP
Sbjct: 377 SIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNP 436

Query: 628 PEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEAR 687
           PEYEF WGLRSY+ETSKMKVL+F  +VQK+DP++W AQ+ EA +  L A   AAAEA+AR
Sbjct: 437 PEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKAR 496

Query: 688 AEARTRMGI--GDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNAR-S 744
           AE R RMGI  G E  +GP +WD           E D G PW++      A     A+ S
Sbjct: 497 AEIRARMGIGLGSENAAGPCNWD-----------EADIG-PWAKARIQAGAEAKAKAQES 544

Query: 745 RFPQTFAGPIIGPGGTASANFAANFGA 771
               T A        +ASA+ +  F A
Sbjct: 545 GSASTGASTSTNNSASASASTSGGFSA 571



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 85/328 (25%), Positives = 129/328 (39%), Gaps = 77/328 (23%)

Query: 1   MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN 60
           M+   + GAGL  FQAEAS +DS+ +MQTL+   Q  E P T +A+ A            
Sbjct: 1   MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSE------- 53

Query: 61  EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK 120
              D++VS A+   K+                + S+   A++ P TQ             
Sbjct: 54  ---DVKVSKASGVSKAT---------------EVSKTPEAREAPATQ------------- 82

Query: 121 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP 180
               A   +Q   T  LAA    +A     A TK             NA+  A + P T 
Sbjct: 83  ----ASSTTQLTDTQVLAAENKSLA-----ADTK-----------KQNADPQAVTMPATE 122

Query: 181 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES 240
            K       +  ADT+   VN     T  A  +      EP+ A AQ+       +N ++
Sbjct: 123 TK-----KVSHVADTK---VNTKAQETEAAPSQAPADEPEPESAAAQSQ------ENQDT 168

Query: 241 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWR-SAPVPVTTQNPPGAPPNVLWQTP 299
           R  ++ K+ RK+ +L+ EE+ S DQ +A    G  R S  +  +        P   W   
Sbjct: 169 RPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARR 228

Query: 300 LAWQNPSGWQNQTARQTPPARQSPPARQ 327
            +    + W    AR+   + +SP AR+
Sbjct: 229 ASRTRLAAW----ARRALLSLRSPKARR 252


>gi|29540551 trophinin isoform 2 [Homo sapiens]
          Length = 706

 Score =  343 bits (881), Expect = 3e-94
 Identities = 166/227 (73%), Positives = 193/227 (85%)

Query: 463 AQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEK 522
           A PRDVA+LQERANKLVKYL++KD TK+PIKRS+MLRD+I+EY + +PEIIERA + LEK
Sbjct: 436 APPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEK 495

Query: 523 KFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVL 582
            F + LKEIDK+  LYILIST ES AGILGTTKDTPKLGLL+VIL VIFMNGN+ASEAV+
Sbjct: 496 MFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVI 555

Query: 583 WEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHET 642
           WE LRK+GLRPGVRH L G++RKL+T EFVKQKYL+Y+RVPNS PPEYEF WGLRSYHET
Sbjct: 556 WEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHET 615

Query: 643 SKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAE 689
           SKMKVL+F   VQK+DP+DW  Q+ EA +  + A   A AEAEARAE
Sbjct: 616 SKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAE 662



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 72/258 (27%), Positives = 106/258 (41%), Gaps = 48/258 (18%)

Query: 36  ISEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFS 95
           I+ A   + A  A    ++Q    NE A I  +AA+ R K A K +    K  N   +  
Sbjct: 216 IASATEVSLAATATHTATTQGQITNETASIHTTAASIRTKKASKARKTIAKVINTDTEHI 275

Query: 96  QAHNAKDVPNTQPKAAF--------KSQNATPKGPNAAYDFSQAATTGELAANKSEMAFK 147
           +A N  D    Q +A+         K + A  +GPN+  + S+A    ++  N+      
Sbjct: 276 EALNVTDAATRQIEASVVAIRPKKSKGKKAASRGPNSVSEISEAPLATQIVTNQ------ 329

Query: 148 AQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVNQ---AK 204
           A  AT +V                      K   +A    TKA   ++QT N +Q   AK
Sbjct: 330 ALAATLRV----------------------KRGSRARKAATKARATESQTPNADQGAQAK 367

Query: 205 MATSQADIETDPGISEPDGATAQTSADGSQAQ-NLESRTIIRGKRTRKINNLNVEENSSG 263
           +A++Q ++     +     A  Q  AD   AQ +LE  T  RGKR RK  +LN +E S  
Sbjct: 368 IASAQTNVSA---LETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKHLNGDERSGS 424

Query: 264 DQRRAPLAAGTWRSAPVP 281
           + RR P     W   P P
Sbjct: 425 NYRRIP-----WGRRPAP 437


>gi|29540541 trophinin isoform 2 [Homo sapiens]
          Length = 706

 Score =  343 bits (881), Expect = 3e-94
 Identities = 166/227 (73%), Positives = 193/227 (85%)

Query: 463 AQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEK 522
           A PRDVA+LQERANKLVKYL++KD TK+PIKRS+MLRD+I+EY + +PEIIERA + LEK
Sbjct: 436 APPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEK 495

Query: 523 KFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVL 582
            F + LKEIDK+  LYILIST ES AGILGTTKDTPKLGLL+VIL VIFMNGN+ASEAV+
Sbjct: 496 MFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVI 555

Query: 583 WEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHET 642
           WE LRK+GLRPGVRH L G++RKL+T EFVKQKYL+Y+RVPNS PPEYEF WGLRSYHET
Sbjct: 556 WEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHET 615

Query: 643 SKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAE 689
           SKMKVL+F   VQK+DP+DW  Q+ EA +  + A   A AEAEARAE
Sbjct: 616 SKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAE 662



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 72/258 (27%), Positives = 106/258 (41%), Gaps = 48/258 (18%)

Query: 36  ISEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFS 95
           I+ A   + A  A    ++Q    NE A I  +AA+ R K A K +    K  N   +  
Sbjct: 216 IASATEVSLAATATHTATTQGQITNETASIHTTAASIRTKKASKARKTIAKVINTDTEHI 275

Query: 96  QAHNAKDVPNTQPKAAF--------KSQNATPKGPNAAYDFSQAATTGELAANKSEMAFK 147
           +A N  D    Q +A+         K + A  +GPN+  + S+A    ++  N+      
Sbjct: 276 EALNVTDAATRQIEASVVAIRPKKSKGKKAASRGPNSVSEISEAPLATQIVTNQ------ 329

Query: 148 AQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVNQ---AK 204
           A  AT +V                      K   +A    TKA   ++QT N +Q   AK
Sbjct: 330 ALAATLRV----------------------KRGSRARKAATKARATESQTPNADQGAQAK 367

Query: 205 MATSQADIETDPGISEPDGATAQTSADGSQAQ-NLESRTIIRGKRTRKINNLNVEENSSG 263
           +A++Q ++     +     A  Q  AD   AQ +LE  T  RGKR RK  +LN +E S  
Sbjct: 368 IASAQTNVSA---LETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKHLNGDERSGS 424

Query: 264 DQRRAPLAAGTWRSAPVP 281
           + RR P     W   P P
Sbjct: 425 NYRRIP-----WGRRPAP 437


>gi|148746206 MAGE-like protein 2 [Homo sapiens]
          Length = 646

 Score =  212 bits (539), Expect = 1e-54
 Identities = 126/324 (38%), Positives = 180/324 (55%), Gaps = 22/324 (6%)

Query: 362 WPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTD 421
           W GP  W N     N   W+     Q    W+ P   +G   W  P    +   W  P+ 
Sbjct: 305 WQGPRPWEN----LNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPS- 359

Query: 422 WPLPPDWIPADWPIPPDWQNL----RPSPNL--------RPSPNSRASQNPGAAQPRDVA 469
                 W  + W  P   + L     P  +L          SP S A+Q+    + + ++
Sbjct: 360 ----ASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVEAQPLS 415

Query: 470 LLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLK 529
            L ERAN LV++L++KD  KVP++RSEM++ I+REY D   +II RA   LE  FG QLK
Sbjct: 416 PLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLK 475

Query: 530 EIDKEEHLYILISTPESLAG-ILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRK 588
           EID + H YI+I+      G ++ +  D PK GLL+V+L +IFM GN   E +++  L K
Sbjct: 476 EIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFK 535

Query: 589 MGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVL 648
           +GL     + L G+ +KL+T  FV+QKYL+YRR+P + P EYEFLWG R++ ETSKM VL
Sbjct: 536 LGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVL 595

Query: 649 RFIAEVQKRDPRDWTAQFMEAADE 672
           RF+A++ K+DP+ W   ++EA  E
Sbjct: 596 RFLAKLHKKDPQSWPFHYLEALAE 619



 Score = 34.7 bits (78), Expect = 0.35
 Identities = 66/310 (21%), Positives = 101/310 (32%), Gaps = 35/310 (11%)

Query: 41  PTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNA 100
           P+ QA  A       PP A     +  + +   P    +  +   +G +     S     
Sbjct: 81  PSWQAPPAVLQAQPGPPVAAANFPLGSAKSLMTPSGECRASSIDRRGSSKERRTSSKERR 140

Query: 101 KDVPNTQPKAAFKSQNATPKGPNAAYDFSQAA-----TTGELAANKSEMAFKAQNATTKV 155
                ++ +  F +    PK  +AA     AA      T E  A  S +      AT++ 
Sbjct: 141 AP---SKDRMIFAATFCAPKAVSAARAHLPAAWKNLPATPETFAPSSSVF----PATSQF 193

Query: 156 GPNATYNFSQSLNANDLANSRP---KTPFKAWNDTTKAPTADTQTQNVNQAKMATSQADI 212
            P +   F     A++   S P   + PF         P       N ++A  A      
Sbjct: 194 QPASLNAFKGPSAASETPKSLPYALQDPFACVEALPAVPWVPQPNMNASKASQAV----- 248

Query: 213 ETDPGISEPDGATAQTSADGSQAQNLESRTIIR-GKRTRKINNLNVEENSSGDQRRAPLA 271
              P       A  Q +A   +A         R GK TRK  +L  +E+S G      LA
Sbjct: 249 ---PTFLMATAAAPQATATTQEASKTSVEPPRRSGKATRKKKHLEAQEDSRGHT----LA 301

Query: 272 AGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNP------SGWQNQTARQTPPARQSPPA 325
              W+  P P    N          Q    W++P      SGW+  +  +     + P A
Sbjct: 302 FHDWQG-PRPWENLNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPSA 360

Query: 326 RQTPPAWQNP 335
                AW+ P
Sbjct: 361 SWALSAWEGP 370


>gi|20162572 necdin-like 2 [Homo sapiens]
          Length = 304

 Score =  203 bits (517), Expect = 4e-52
 Identities = 100/227 (44%), Positives = 158/227 (69%), Gaps = 4/227 (1%)

Query: 450 PSPN-SRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDV 508
           PSP  +R +Q   A  PR    L+ + ++LV++L++KD  K+PIKR+++L+ +I +Y D+
Sbjct: 63  PSPQGARRAQAAPAVGPRSQKQLELKVSELVQFLLIKDQKKIPIKRADILKHVIGDYKDI 122

Query: 509 YPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTKD--TPKLGLLLVI 566
           +P++ +RA   L+  FG +L E++ + + YILI+T E +        D  TP  GLL+++
Sbjct: 123 FPDLFKRAAERLQYVFGYKLVELEPKSNTYILINTLEPVEEDAEMRGDQGTPTTGLLMIV 182

Query: 567 LGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSN 626
           LG+IFM GN   E   W+ LR++G+ P  +H + GD +KL+T +FV+Q+YL+YRR+P+++
Sbjct: 183 LGLIFMKGNTIKETEAWDFLRRLGVYPTKKHLIFGDPKKLITEDFVRQRYLEYRRIPHTD 242

Query: 627 PPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEA-ADE 672
           P +YEF WG R+  ETSKMKVL+F+A+V  +DP+DW AQ+ EA ADE
Sbjct: 243 PVDYEFQWGPRTNLETSKMKVLKFVAKVHNQDPKDWPAQYCEALADE 289


>gi|29826296 melanoma antigen family F, 1 [Homo sapiens]
          Length = 307

 Score =  200 bits (509), Expect = 4e-51
 Identities = 113/252 (44%), Positives = 158/252 (62%), Gaps = 15/252 (5%)

Query: 454 SRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEII 513
           +RA      A+ R    L     +LV++L++KD  K PI RSEM++ +I +   ++P+II
Sbjct: 59  ARALAAKALARRRAYRRLNRTVAELVQFLLVKDKKKSPITRSEMVKYVIGDLKILFPDII 118

Query: 514 ERACFVLEKKFGIQLKEIDKEEHLYILIST--------PESLAGILGTTKDTPKLGLLLV 565
            RA   L   FG +LK+ D++ H YILI+          E L G      D P+LGLL++
Sbjct: 119 ARAAEHLRYVFGFELKQFDRKHHTYILINKLKPLEEEEEEDLGG------DGPRLGLLMM 172

Query: 566 ILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNS 625
           ILG+I+M GN A EA +WE LR++G++P   H L G  ++L+  +FV+Q+YL YRRVP++
Sbjct: 173 ILGLIYMRGNSAREAQVWEMLRRLGVQPSKYHFLFGYPKRLIMEDFVQQRYLSYRRVPHT 232

Query: 626 NPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEA-ADEALDALDAAAAEA 684
           NPPEYEF WG RS  E SKM+VL F+A++ K++P+ W  Q+ EA ADEA  A   A AEA
Sbjct: 233 NPPEYEFSWGPRSNLEISKMEVLGFVAKLHKKEPQHWPVQYREALADEADRARAKARAEA 292

Query: 685 EARAEARTRMGI 696
             RA A  R GI
Sbjct: 293 SMRARASARAGI 304


>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
          Length = 957

 Score =  188 bits (478), Expect = 1e-47
 Identities = 189/696 (27%), Positives = 294/696 (42%), Gaps = 88/696 (12%)

Query: 30  LMEAIQISEAPPTNQA-TAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGP 88
           +++ +  SE P T+   T+A  P +  PPT +E      S+A+ +P  +     +    P
Sbjct: 54  ILQGLCASEGPSTSVLPTSAEGPSTFVPPTISE-----ASSASGQPTISEGPGTSVLPTP 108

Query: 89  N-GVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTGELAANKSEMAFK 147
           + G+        +K +  +   AA + +N +    ++    +    T     + S     
Sbjct: 109 SEGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSLPPTP 168

Query: 148 AQNATTKVGPNATYNFSQSLNAN-DLANSRPKTPFKAWNDTTKAPTADTQTQNVNQAKMA 206
            +  +T V P A    S S+    D   S    P       T  P A T+        ++
Sbjct: 169 GEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGEGPGTSVPLAATEG-------LS 221

Query: 207 TS-QADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNLNVEENSSGDQ 265
           TS QA  +  P  S P  AT   S      ++    T +        +   +   S G  
Sbjct: 222 TSVQATPDEGPSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPGEGPSTSVLPAASDGQS 281

Query: 266 RRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQTPPARQSPPA 325
                  G   S  VP T     G   +V        Q  +G  + T+   PP      +
Sbjct: 282 ISLVPTRGKGSSTSVPPTATE--GLSTSV--------QPTAGEGSSTS--VPPTPGGGLS 329

Query: 326 RQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNP---LAWQNPPGWQT 382
              PP     ++   P               P P   P   V P P   L+   PP    
Sbjct: 330 TSVPPTATEELSTSVP---------------PTPGEGPSTSVLPIPGEGLSTSVPPTASD 374

Query: 383 PPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPIPPDWQNL 442
                 PP    P +       P  PD P     P P + P       A     P   +L
Sbjct: 375 GSDTSVPPT---PGEGASTLVQPTAPDGPGSSVLPNPGEGPSTLFSSSASVDRNPSKCSL 431

Query: 443 -RPSPNLRPSPNSRASQNPGAAQ-------------PRDVALL----------------- 471
             PSP +  +     S+ P  A+             P  ++++                 
Sbjct: 432 VLPSPRVTKASVDSDSEGPKGAEGPIEFEVLRDCESPNSISIMGLNTSRVAITLKPQDPM 491

Query: 472 QERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEI 531
           ++   +L+++L++KD +K PI+ SEM   I++EY + +PEI+ RA   LE  F  +L+E+
Sbjct: 492 EQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFELREL 551

Query: 532 DKEEHLYILIST--PESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKM 589
           D E H YIL++   P    G L  + + PK+GLL++ILG IF+NGN+A EA +WE L +M
Sbjct: 552 DPEAHTYILLNKLGPVPFEG-LEESPNGPKMGLLMMILGQIFLNGNQAKEAEIWEMLWRM 610

Query: 590 GLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLR 649
           G++   R  + G+ ++LL+ EFV Q+YLDYR V +  P EYEF WG RS+ ET+KMK+L+
Sbjct: 611 GVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMKILK 670

Query: 650 FIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAE 685
           F+A++  +DP DW  ++ EA +E     DAA A AE
Sbjct: 671 FMAKIYNKDPMDWPEKYNEALEE-----DAARAFAE 701



 Score =  147 bits (372), Expect = 3e-35
 Identities = 91/280 (32%), Positives = 145/280 (51%), Gaps = 28/280 (10%)

Query: 413 PPDWPLPTDWPLPPDWIPADWPIPPDWQNLRPSPNLR-----------PSPNSRASQNPG 461
           P DWP   +  L  D   A       WQ L   P+ R           PSP+S  S    
Sbjct: 680 PMDWPEKYNEALEEDAARA---FAEGWQAL---PHFRRPFFEEAAAEVPSPDSEVSSYSS 733

Query: 462 AAQPRD--VALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFV 519
              P     + L+ +A KLV+  +L D TK+PI +  +L  I RE + V+P+++ RA   
Sbjct: 734 KYAPHSWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAART 793

Query: 520 LEKKFGIQLKEIDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGVIFMNGNRAS 578
           L   +G +L  +D   H Y L +  E      +  + + P    L+ +L  IF+ GN A 
Sbjct: 794 LNHVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHAR 853

Query: 579 EAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRS 638
           E+ +W  LR +G++ G +H        ++T  ++ Q+Y+D  RVP+S+P +YEF+WG R+
Sbjct: 854 ESAVWAFLRGLGVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRA 905

Query: 639 YHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALD 678
             ETSKMK LR++A + +++P+DW  Q+ EA ++  +  D
Sbjct: 906 RLETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRAD 945


>gi|73623441 melanoma antigen family B, 10 [Homo sapiens]
          Length = 347

 Score =  174 bits (441), Expect = 3e-43
 Identities = 91/228 (39%), Positives = 139/228 (60%), Gaps = 4/228 (1%)

Query: 471 LQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKE 530
           + E+   LV YL+ K   K PI +++MLR++ +     +P I+ RA   LE  FG+ LKE
Sbjct: 111 VDEKVIILVHYLLYKYQMKEPITKADMLRNVTQMSKSQFPVILSRASEHLELIFGLDLKE 170

Query: 531 IDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKM 589
           ++  +H+Y+L++  +      L      PK GLL+ +LG+IF NGN  +E  +W+    M
Sbjct: 171 VEPNKHIYVLVNKLDLGCDAKLSDETGVPKTGLLMTVLGIIFTNGNCVAEEEVWKVFNTM 230

Query: 590 GLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLR 649
           GL  G+ H + G+ RKLLT + VK+ YL+Y++VPNS+PP Y+FLWG R++ ETSKMKVL 
Sbjct: 231 GLYDGIEHFMFGEPRKLLTKDLVKENYLEYQQVPNSDPPRYQFLWGPRAHAETSKMKVLE 290

Query: 650 FIAEVQKRDPRD---WTAQFMEAADEALDALDAAAAEAEARAEARTRM 694
           F+A+V    P +   W  + ++  +E   A  AA A   A A AR+++
Sbjct: 291 FLAKVNDTAPSEFSNWYTEALQDEEERARARVAAKARVSATAGARSKV 338


>gi|29171714 melanoma antigen family B, 3 [Homo sapiens]
          Length = 346

 Score =  171 bits (434), Expect = 2e-42
 Identities = 91/209 (43%), Positives = 135/209 (64%), Gaps = 1/209 (0%)

Query: 474 RANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDK 533
           + N LV++LM     K PI +++ML+ + + + + +PEI+++A F +E  FG+ LK++D 
Sbjct: 114 KTNMLVQFLMEMYKMKKPIMKADMLKIVQKSHKNCFPEILKKASFNMEVVFGVDLKKVDS 173

Query: 534 EEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLR 592
            +  Y+L+S  +    G +   +  PK GLLL +LGVIFM GN A+E  +WE L KM + 
Sbjct: 174 TKDSYVLVSKMDLPNNGTVTRGRGFPKTGLLLNLLGVIFMKGNCATEEKIWEFLNKMRIY 233

Query: 593 PGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIA 652
            G +H + G+ RKL+T + VK KYL+YR+VPNSNP  YEFLWG R++ ETSKMKVL F A
Sbjct: 234 DGKKHFIFGEPRKLITQDLVKLKYLEYRQVPNSNPARYEFLWGPRAHAETSKMKVLEFWA 293

Query: 653 EVQKRDPRDWTAQFMEAADEALDALDAAA 681
           +V K  P  +   + EA  +  + + AAA
Sbjct: 294 KVNKTVPSAFQFWYEEALRDEEERVQAAA 322


>gi|4505349 necdin [Homo sapiens]
          Length = 321

 Score =  169 bits (429), Expect = 7e-42
 Identities = 101/272 (37%), Positives = 151/272 (55%), Gaps = 12/272 (4%)

Query: 412 LPPDWPL--PTDWPLPPDWIPADWPIPPDWQNLRPSPNL--RPSPNSRASQNPGAAQPRD 467
           +PP   L  P   PL P   P   P PP   N    P    + +   RA Q P AAQP  
Sbjct: 32  VPPSATLAEPQSPPLGPTAAPQAAP-PPQAPNDEGDPKALQQAAEEGRAHQAPSAAQPGP 90

Query: 468 V----ALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKK 523
                A L ++A++L+ Y+++KD  K+ I   +M++D+I  Y      I+ R   +L + 
Sbjct: 91  APPAPAQLVQKAHELMWYVLVKDQKKMIIWFPDMVKDVIGSYKKWCRSILRRTSLILARV 150

Query: 524 FGIQLKEIDKEEHLYILIST--PESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAV 581
           FG+ L+        + L+    PE L  +  + +  P  GLLL+IL +I++ G  A E+ 
Sbjct: 151 FGLHLRLTSLHTMEFALVKALEPEELDRVALSNR-MPMTGLLLMILSLIYVKGRGARESA 209

Query: 582 LWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHE 641
           +W  LR +GLRP  +H   GD+RKL+T EFV+  YL Y+RVP   PPEYEF WG R+  E
Sbjct: 210 VWNVLRILGLRPWKKHSTFGDVRKLITEEFVQMNYLKYQRVPYVEPPEYEFFWGSRASRE 269

Query: 642 TSKMKVLRFIAEVQKRDPRDWTAQFMEAADEA 673
            +KM+++ F+A V K+DP+ W +++ EA +EA
Sbjct: 270 ITKMQIMEFLARVFKKDPQAWPSRYREALEEA 301


>gi|58530863 melanoma antigen family A, 10 [Homo sapiens]
          Length = 369

 Score =  168 bits (426), Expect = 2e-41
 Identities = 108/347 (31%), Positives = 172/347 (49%), Gaps = 16/347 (4%)

Query: 371 PLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPD--W 428
           PLA +      T      P  +           +PL P    P +     + P PP    
Sbjct: 31  PLAVEEDASSSTSTSSSFPSSFPSSSSSSSSSCYPLIPS--TPEEVSADDETPNPPQSAQ 88

Query: 429 IPADWP-----IPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLM 483
           I    P     +P D  +   S     SP++        + PR    + E+   LV++L+
Sbjct: 89  IACSSPSVVASLPLDQSDEGSSSQKEESPSTLQVLPDSESLPRSE--IDEKVTDLVQFLL 146

Query: 484 LKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILI-S 542
            K   K PI ++E+L  +I+ Y D +P +   A   +   FGI +KE+D   H ++L+ S
Sbjct: 147 FKYQMKEPITKAEILESVIKNYEDHFPLLFSEASECMLLVFGIDVKEVDPTGHSFVLVTS 206

Query: 543 TPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGD 602
              +  G+L   +  PK G+L++IL +IF+ G    E V+WEAL  MGL  G+ H + G+
Sbjct: 207 LGLTYDGMLSDVQSMPKTGILILILSIIFIEGYCTPEEVIWEALNMMGLYDGMEHLIYGE 266

Query: 603 LRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDW 662
            RKLLT ++V++ YL+YR+VP S+P  YEFLWG R++ E  KM +L+F+A+V   DPR +
Sbjct: 267 PRKLLTQDWVQENYLEYRQVPGSDPARYEFLWGPRAHAEIRKMSLLKFLAKVNGSDPRSF 326

Query: 663 TAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDD 709
              +    +EAL   +  A +  A  +  T M     + +G +S+ +
Sbjct: 327 PLWY----EEALKDEEERAQDRIATTDDTTAMASASSSATGSFSYPE 369


>gi|10567820 melanoma antigen family A, 10 [Homo sapiens]
          Length = 369

 Score =  168 bits (426), Expect = 2e-41
 Identities = 108/347 (31%), Positives = 172/347 (49%), Gaps = 16/347 (4%)

Query: 371 PLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPD--W 428
           PLA +      T      P  +           +PL P    P +     + P PP    
Sbjct: 31  PLAVEEDASSSTSTSSSFPSSFPSSSSSSSSSCYPLIPS--TPEEVSADDETPNPPQSAQ 88

Query: 429 IPADWP-----IPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLM 483
           I    P     +P D  +   S     SP++        + PR    + E+   LV++L+
Sbjct: 89  IACSSPSVVASLPLDQSDEGSSSQKEESPSTLQVLPDSESLPRSE--IDEKVTDLVQFLL 146

Query: 484 LKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILI-S 542
            K   K PI ++E+L  +I+ Y D +P +   A   +   FGI +KE+D   H ++L+ S
Sbjct: 147 FKYQMKEPITKAEILESVIKNYEDHFPLLFSEASECMLLVFGIDVKEVDPTGHSFVLVTS 206

Query: 543 TPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGD 602
              +  G+L   +  PK G+L++IL +IF+ G    E V+WEAL  MGL  G+ H + G+
Sbjct: 207 LGLTYDGMLSDVQSMPKTGILILILSIIFIEGYCTPEEVIWEALNMMGLYDGMEHLIYGE 266

Query: 603 LRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDW 662
            RKLLT ++V++ YL+YR+VP S+P  YEFLWG R++ E  KM +L+F+A+V   DPR +
Sbjct: 267 PRKLLTQDWVQENYLEYRQVPGSDPARYEFLWGPRAHAEIRKMSLLKFLAKVNGSDPRSF 326

Query: 663 TAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDD 709
              +    +EAL   +  A +  A  +  T M     + +G +S+ +
Sbjct: 327 PLWY----EEALKDEEERAQDRIATTDDTTAMASASSSATGSFSYPE 369


>gi|27734781 melanoma antigen family B, 18 [Homo sapiens]
          Length = 343

 Score =  168 bits (426), Expect = 2e-41
 Identities = 108/288 (37%), Positives = 158/288 (54%), Gaps = 22/288 (7%)

Query: 425 PPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVAL-------------L 471
           P +   A+ P  P+     PS     +P S  S N GA+   + +L             L
Sbjct: 49  PQNLPAAETPSIPEALQGAPSTTNAIAPVS-CSSNEGASSQDEKSLGSSREAEGWKEDPL 107

Query: 472 QERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEI 531
            ++   LV +L+ K  TK PI + +M++ +IR+    + EI++RA   +E   G+ LKE+
Sbjct: 108 NKKVVSLVHFLLQKYETKEPITKGDMIKFVIRKDKCHFNEILKRASEHMELALGVDLKEV 167

Query: 532 DKEEHLYILISTPESLAGILGTTKDT---PKLGLLLVILGVIFMNGNRASEAVLWEALRK 588
           D   H Y   S  +       TT D    PK GLL++ LGVIF+NGNRA E  +WE +  
Sbjct: 168 DPIRHYYAFFSKLDLTYD--ETTSDEEKIPKTGLLMIALGVIFLNGNRAPEEAVWEIMNM 225

Query: 589 MGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVL 648
           MG+    +H L GD RK++T + V+ KYL+Y++VPNS+PP YEFLWG R++ ETSKMKVL
Sbjct: 226 MGVYADRKHFLYGDPRKVMTKDLVQLKYLEYQQVPNSDPPRYEFLWGPRAHAETSKMKVL 285

Query: 649 RFIAEVQKRDPRDWTAQFMEA---ADEALDALDAAAAEAEARAEARTR 693
            F+A++    P  + + + EA    ++   A  AA A   A A AR+R
Sbjct: 286 EFVAKIHDTVPSAFPSCYEEALRDEEQRTQARAAARAHTAAMANARSR 333


>gi|153791873 melanoma antigen family B, 16 [Homo sapiens]
          Length = 324

 Score =  167 bits (424), Expect = 3e-41
 Identities = 93/229 (40%), Positives = 139/229 (60%), Gaps = 7/229 (3%)

Query: 451 SPNSRASQNPGAAQ----PRDVAL--LQERANKLVKYLMLKDYTKVPIKRSEMLRDIIRE 504
           S N     +P +++    PR+V    L ++   LV +++ K   K PI +++ML+ II++
Sbjct: 87  SSNQEEEDSPSSSEDTSDPRNVPADALDQKVAFLVNFMLHKCQMKKPITKADMLKIIIKD 146

Query: 505 YTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLY-ILISTPESLAGILGTTKDTPKLGLL 563
               + EI+ RA   LE  FG+ + E+D   H Y + I    +  G+L   K  PK GLL
Sbjct: 147 DESHFSEILLRASEHLEMIFGLDVVEVDPTTHCYGLFIKLGLTYDGMLSGEKGVPKTGLL 206

Query: 564 LVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVP 623
           +++LGVIFM GNRA+E  +WE L   G+  G +H + G+ R L+T +FVK+KYL+Y++V 
Sbjct: 207 IIVLGVIFMKGNRATEEEVWEVLNLTGVYSGKKHFIFGEPRMLITKDFVKEKYLEYQQVA 266

Query: 624 NSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADE 672
           NS+P  YEFLWG R+  ETSKMKVL F+A+V    P  + +Q+ EA  E
Sbjct: 267 NSDPARYEFLWGPRAKAETSKMKVLEFVAKVHGSYPHSFPSQYAEALKE 315


>gi|61744473 melanoma antigen family A, 11 isoform b [Homo sapiens]
          Length = 400

 Score =  166 bits (421), Expect = 6e-41
 Identities = 90/219 (41%), Positives = 131/219 (59%), Gaps = 3/219 (1%)

Query: 457 SQNPGAAQPRDVA--LLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIE 514
           S +P    P   +  +L ++   LV  L+ K   K  I ++EML  +I+ Y D +PEI  
Sbjct: 177 STSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVKGLITKAEMLGSVIKNYEDYFPEIFR 236

Query: 515 RACFVLEKKFGIQLKEIDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGVIFMN 573
            A   ++  FGI +KE+D   H Y+L+++   S  GI    +  PK GLL+++LGVIFM 
Sbjct: 237 EASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDGIQCNEQSMPKSGLLIIVLGVIFME 296

Query: 574 GNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFL 633
           GN   E V+WE L  MG+  G  H L G+ ++LLT  +V++KYL YR+VP ++P  YEFL
Sbjct: 297 GNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLTQNWVQEKYLVYRQVPGTDPACYEFL 356

Query: 634 WGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADE 672
           WG R++ ETSKMKVL +IA    RDP  + + + +A  E
Sbjct: 357 WGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDALRE 395


>gi|65507078 melanoma antigen family A, 11 isoform a [Homo sapiens]
          Length = 429

 Score =  166 bits (421), Expect = 6e-41
 Identities = 90/219 (41%), Positives = 131/219 (59%), Gaps = 3/219 (1%)

Query: 457 SQNPGAAQPRDVA--LLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIE 514
           S +P    P   +  +L ++   LV  L+ K   K  I ++EML  +I+ Y D +PEI  
Sbjct: 206 STSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVKGLITKAEMLGSVIKNYEDYFPEIFR 265

Query: 515 RACFVLEKKFGIQLKEIDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGVIFMN 573
            A   ++  FGI +KE+D   H Y+L+++   S  GI    +  PK GLL+++LGVIFM 
Sbjct: 266 EASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDGIQCNEQSMPKSGLLIIVLGVIFME 325

Query: 574 GNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFL 633
           GN   E V+WE L  MG+  G  H L G+ ++LLT  +V++KYL YR+VP ++P  YEFL
Sbjct: 326 GNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLTQNWVQEKYLVYRQVPGTDPACYEFL 385

Query: 634 WGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADE 672
           WG R++ ETSKMKVL +IA    RDP  + + + +A  E
Sbjct: 386 WGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDALRE 424


>gi|4505085 melanoma antigen family B, 4 [Homo sapiens]
          Length = 346

 Score =  166 bits (419), Expect = 1e-40
 Identities = 95/256 (37%), Positives = 146/256 (57%), Gaps = 13/256 (5%)

Query: 453 NSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEI 512
           N+ +SQ   + +      L  +   LV++L+ K   K P  ++EML+ I ++Y + +PEI
Sbjct: 91  NASSSQASTSTERSLKDSLTRKTKMLVQFLLYKYKMKEPTTKAEMLKIISKKYKEHFPEI 150

Query: 513 IERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGVIFM 572
             +     E  FG+ LKE++   H YIL+S      G   +    P+ GLL+ +L VIF+
Sbjct: 151 FRKVSQRTELVFGLALKEVNPTTHSYILVSMLGPNDGNQSSAWTLPRNGLLMPLLSVIFL 210

Query: 573 NGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEF 632
           NGN A E  +WE L  +G+  G RH + G+ RKL+T + V++KYL+Y++VPNS+PP Y+F
Sbjct: 211 NGNCAREEEIWEFLNMLGIYDGKRHLIFGEPRKLITQDLVQEKYLEYQQVPNSDPPRYQF 270

Query: 633 LWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAEART 692
           LWG R++ ETSKMKVL F+A+V    P ++   + E           A  + E RA AR 
Sbjct: 271 LWGPRAHAETSKMKVLEFLAKVNDTTPNNFPLLYEE-----------ALRDEEERAGARP 319

Query: 693 RMGI--GDEAVSGPWS 706
           R+    G  A++  +S
Sbjct: 320 RVAARRGTTAMTSAYS 335


>gi|19923308 melanoma antigen family A, 8 [Homo sapiens]
          Length = 318

 Score =  166 bits (419), Expect = 1e-40
 Identities = 86/203 (42%), Positives = 126/203 (62%), Gaps = 1/203 (0%)

Query: 471 LQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKE 530
           L E+  +LV++L+ K   K P+ ++EML  +I+ Y + +P+I  +A   ++  FGI +KE
Sbjct: 112 LDEKVAELVRFLLRKYQIKEPVTKAEMLESVIKNYKNHFPDIFSKASECMQVIFGIDVKE 171

Query: 531 IDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKM 589
           +D   H YIL++    S  G+LG  + TPK GLL+++LG+I M G+RA E  +WEAL  M
Sbjct: 172 VDPAGHSYILVTCLGLSYDGLLGDDQSTPKTGLLIIVLGMILMEGSRAPEEAIWEALSVM 231

Query: 590 GLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLR 649
           GL  G  H +   LRKLLT E+V++ YL+YR+ P S+P  YEFLWG R+  ETS +KVL 
Sbjct: 232 GLYDGREHSVYWKLRKLLTQEWVQENYLEYRQAPGSDPVRYEFLWGPRALAETSYVKVLE 291

Query: 650 FIAEVQKRDPRDWTAQFMEAADE 672
            +  V  R    + +   EA  E
Sbjct: 292 HVVRVNARVRISYPSLHEEALGE 314


>gi|169216977 PREDICTED: melanoma antigen family B, 17 [Homo
           sapiens]
          Length = 457

 Score =  164 bits (414), Expect = 4e-40
 Identities = 96/244 (39%), Positives = 144/244 (59%), Gaps = 6/244 (2%)

Query: 451 SPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYP 510
           SPNS    +   +  RD  LL  +  +LV++L+ K   K PI R  ML+ I R+Y   +P
Sbjct: 212 SPNSFHGPSSSESTGRD--LLNTKTGELVQFLLNKYIRKEPITREAMLKVINRKYKQHFP 269

Query: 511 EIIERACFVLEKKFGIQLKEIDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGV 569
           EI+ R+   +E  FG+ LKE+D     Y+L+   +    G L      P  GLL+V+L  
Sbjct: 270 EILRRSTENVEVVFGLYLKEMDPSRQSYVLVGKLDFPNQGSLSDGGGFPLSGLLMVLLST 329

Query: 570 IFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPE 629
           IFM+GNRA+E  +WE L  +G+  G +H + G+ ++L+T + V++ YL+Y++VP+S+PP 
Sbjct: 330 IFMHGNRATEEEMWECLNALGMYKGRKHFIYGEPQELVTKDLVREGYLEYQQVPSSDPPR 389

Query: 630 YEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAE 689
           YEFLWG R+  ETSKMKVL F+A++       + +++ EA  E     + A A A AR  
Sbjct: 390 YEFLWGPRARAETSKMKVLEFVAKLNDTVASTYKSRYEEALRE---EEEQARARAVARDS 446

Query: 690 ARTR 693
           AR R
Sbjct: 447 ARAR 450


>gi|169216191 PREDICTED: melanoma antigen family B, 17 [Homo
           sapiens]
          Length = 457

 Score =  164 bits (414), Expect = 4e-40
 Identities = 96/244 (39%), Positives = 144/244 (59%), Gaps = 6/244 (2%)

Query: 451 SPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYP 510
           SPNS    +   +  RD  LL  +  +LV++L+ K   K PI R  ML+ I R+Y   +P
Sbjct: 212 SPNSFHGPSSSESTGRD--LLNTKTGELVQFLLNKYIRKEPITREAMLKVINRKYKQHFP 269

Query: 511 EIIERACFVLEKKFGIQLKEIDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGV 569
           EI+ R+   +E  FG+ LKE+D     Y+L+   +    G L      P  GLL+V+L  
Sbjct: 270 EILRRSTENVEVVFGLYLKEMDPSRQSYVLVGKLDFPNQGSLSDGGGFPLSGLLMVLLST 329

Query: 570 IFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPE 629
           IFM+GNRA+E  +WE L  +G+  G +H + G+ ++L+T + V++ YL+Y++VP+S+PP 
Sbjct: 330 IFMHGNRATEEEMWECLNALGMYKGRKHFIYGEPQELVTKDLVREGYLEYQQVPSSDPPR 389

Query: 630 YEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAE 689
           YEFLWG R+  ETSKMKVL F+A++       + +++ EA  E     + A A A AR  
Sbjct: 390 YEFLWGPRARAETSKMKVLEFVAKLNDTVASTYKSRYEEALRE---EEEQARARAVARDS 446

Query: 690 ARTR 693
           AR R
Sbjct: 447 ARAR 450


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,898,348
Number of Sequences: 37866
Number of extensions: 2347804
Number of successful extensions: 16981
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 233
Number of HSP's successfully gapped in prelim test: 434
Number of HSP's that attempted gapping in prelim test: 8115
Number of HSP's gapped (non-prelim): 6080
length of query: 778
length of database: 18,247,518
effective HSP length: 110
effective length of query: 668
effective length of database: 14,082,258
effective search space: 9406948344
effective search space used: 9406948344
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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