Guide to the Human Genome
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Search of human proteins with 5174535

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5174535 melanocortin 5 receptor [Homo sapiens]
         (325 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5174535 melanocortin 5 receptor [Homo sapiens]                     652   0.0  
gi|170671732 melanocortin 3 receptor [Homo sapiens]                   393   e-109
gi|119508433 melanocortin 4 receptor [Homo sapiens]                   392   e-109
gi|4505127 melanocortin 2 receptor [Homo sapiens]                     281   7e-76
gi|193083134 melanocortin 1 receptor [Homo sapiens]                   275   4e-74
gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]           129   5e-30
gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]           129   5e-30
gi|4885295 G protein-coupled receptor 12 [Homo sapiens]               118   6e-27
gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]         117   1e-26
gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens]            116   2e-26
gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens]         115   5e-26
gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens]            114   1e-25
gi|4885325 G protein-coupled receptor 3 [Homo sapiens]                113   2e-25
gi|5921992 adenosine A2a receptor [Homo sapiens]                      113   3e-25
gi|134244587 endothelial differentiation, sphingolipid G-protein...   106   2e-23
gi|4501951 adenosine A2b receptor [Homo sapiens]                      103   2e-22
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]                101   1e-21
gi|13540517 endothelial differentiation, sphingolipid G-protein-...   100   2e-21
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]                100   3e-21
gi|115305569 adenosine A1 receptor [Homo sapiens]                      99   4e-21
gi|4501947 adenosine A1 receptor [Homo sapiens]                        99   4e-21
gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]           96   6e-20
gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]           96   6e-20
gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]           96   6e-20
gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]           96   6e-20
gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]            96   6e-20
gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]           96   6e-20
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]     94   2e-19
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]     94   2e-19
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]     94   2e-19

>gi|5174535 melanocortin 5 receptor [Homo sapiens]
          Length = 325

 Score =  652 bits (1682), Expect = 0.0
 Identities = 325/325 (100%), Positives = 325/325 (100%)

Query: 1   MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGA 60
           MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGA
Sbjct: 1   MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGA 60

Query: 61  IVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDS 120
           IVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDS
Sbjct: 61  IVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDS 120

Query: 121 MICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILY 180
           MICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILY
Sbjct: 121 MICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILY 180

Query: 181 SESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTV 240
           SESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTV
Sbjct: 181 SESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTV 240

Query: 241 TMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQ 300
           TMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQ
Sbjct: 241 TMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQ 300

Query: 301 EMRKTFKEIICCRGFRIACSFPRRD 325
           EMRKTFKEIICCRGFRIACSFPRRD
Sbjct: 301 EMRKTFKEIICCRGFRIACSFPRRD 325


>gi|170671732 melanocortin 3 receptor [Homo sapiens]
          Length = 323

 Score =  393 bits (1009), Expect = e-109
 Identities = 197/322 (61%), Positives = 250/322 (77%), Gaps = 5/322 (1%)

Query: 1   MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSP--CEDMGIAVEVFLTLGVISLLENILVI 58
           MN+S  L  +   L     +L  P   N+SS   CE + I  EVFL+LG++SLLENILVI
Sbjct: 1   MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVI 60

Query: 59  GAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVF 118
            A+V+N NLHSPMYFF+CSLAVADMLVS+S+A ETI I ++++ +L   D F++H+DN+F
Sbjct: 61  LAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIF 120

Query: 119 DSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFI 178
           DSMICIS+VAS+C+LLAIAVDRYVTIFYALRYH IMT R++  +I  IW  C  CG+VFI
Sbjct: 121 DSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFI 180

Query: 179 LYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGAS--SARQRTSMQG 236
           +YSES  VI+CLI+MFFAM+ L+ +LY+HMFL AR HVKRIAALP A   + +Q + M+G
Sbjct: 181 VYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKG 240

Query: 237 AVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYA 296
           AVT+T+LLGVF  CWAPFFLHL L+++CP N YC  + +HFN YL+LIMCNSV+DPLIYA
Sbjct: 241 AVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYA 300

Query: 297 FRSQEMRKTFKEIIC-CRGFRI 317
           FRS E+R TF+EI+C C G  +
Sbjct: 301 FRSLELRNTFREILCGCNGMNL 322


>gi|119508433 melanocortin 4 receptor [Homo sapiens]
          Length = 332

 Score =  392 bits (1008), Expect = e-109
 Identities = 194/291 (66%), Positives = 235/291 (80%), Gaps = 1/291 (0%)

Query: 34  EDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWET 93
           E + ++ EVF+TLGVISLLENILVI AI KNKNLHSPMYFF+CSLAVADMLVS+S+  ET
Sbjct: 42  EQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSET 101

Query: 94  ITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHI 153
           I I LLN+     A +F  +IDNV DS+IC S++AS+CSLL+IAVDRY TIFYAL+YH+I
Sbjct: 102 IVITLLNSTD-TDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNI 160

Query: 154 MTARRSGAIIAGIWAFCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLAR 213
           MT +R G II+ IWA CT  GI+FI+YS+S+ VI+CLI+MFF ML L+ SLY+HMFL+AR
Sbjct: 161 MTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMAR 220

Query: 214 THVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRF 273
            H+KRIA LPG  + RQ  +M+GA+T+T+L+GVF VCWAPFFLHL   +SCPQN YC  F
Sbjct: 221 LHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCF 280

Query: 274 MSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRGFRIACSFPRR 324
           MSHFN+YLILIMCNS++DPLIYA RSQE+RKTFKEIICC      C    R
Sbjct: 281 MSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSR 331


>gi|4505127 melanocortin 2 receptor [Homo sapiens]
          Length = 297

 Score =  281 bits (718), Expect = 7e-76
 Identities = 134/288 (46%), Positives = 194/288 (67%), Gaps = 7/288 (2%)

Query: 25  NVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADML 84
           N    +S C  + +  E+F T+ ++ +LEN++V+ A+ KNKNL +PMYFF+CSLA++DML
Sbjct: 13  NTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVFKNKNLQAPMYFFICSLAISDML 72

Query: 85  VSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTI 144
            S+    E I I L N  +L    +F    D++ DS+  +S++ S+ SL  IA DRY+TI
Sbjct: 73  GSLYKILENILIILRNMGYLKPRGSFETTADDIIDSLFVLSLLGSIFSLSVIAADRYITI 132

Query: 145 FYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSL 204
           F+ALRYH I+T RR+  ++  IW FCTG GI  +++S     ++   S+F  ML  ++ L
Sbjct: 133 FHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIFSHHVPTVITFTSLFPLMLVFILCL 192

Query: 205 YIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSC 264
           Y+HMFLLAR+H ++I+ LP       R +M+GA+T+T+LLGVF  CWAPF LH+ LM  C
Sbjct: 193 YVHMFLLARSHTRKISTLP-------RANMKGAITLTILLGVFIFCWAPFVLHVLLMTFC 245

Query: 265 PQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICC 312
           P N YC+ +MS F +  +LIMCN+V+DP IYAFRS E+R  FK++I C
Sbjct: 246 PSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSPELRDAFKKMIFC 293


>gi|193083134 melanocortin 1 receptor [Homo sapiens]
          Length = 317

 Score =  275 bits (703), Expect = 4e-74
 Identities = 135/281 (48%), Positives = 191/281 (67%), Gaps = 1/281 (0%)

Query: 33  CEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWE 92
           C ++ I+  +FL+LG++SL+EN LV+  I KN+NLHSPMY F+C LA++D+LVS S+  E
Sbjct: 35  CLEVSISDGLFLSLGLVSLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLE 94

Query: 93  TITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHH 152
           T  I LL    LV   A ++ +DNV D + C S+++S+C L AIAVDRY++IFYALRYH 
Sbjct: 95  TAVILLLEAGALVARAAVLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHS 154

Query: 153 IMTARRSGAIIAGIWAFCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLA 212
           I+T  R+   +A IW        +FI Y +   V+LCL+  F AML L+  LY+HM   A
Sbjct: 155 IVTLPRARRAVAAIWVASVVFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARA 214

Query: 213 RTHVKRIAAL-PGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCS 271
             H + IA L        Q   ++GAVT+T+LLG+F +CW PFFLHLTL++ CP++  C 
Sbjct: 215 CQHAQGIARLHKRQRPVHQGFGLKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCG 274

Query: 272 RFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICC 312
               +FN++L LI+CN+++DPLIYAF SQE+R+T KE++ C
Sbjct: 275 CIFKNFNLFLALIICNAIIDPLIYAFHSQELRRTLKEVLTC 315


>gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]
          Length = 364

 Score =  129 bits (323), Expect = 5e-30
 Identities = 84/292 (28%), Positives = 145/292 (49%), Gaps = 41/292 (14%)

Query: 44  LTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLL---- 99
           +T+ +  +L N+LV+ AI  N+  H P+Y+ + +LA AD    ++        YL+    
Sbjct: 57  ITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAY------FYLMFNTG 110

Query: 100 -NNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARR 158
            N + L ++   +R        +I  S+ AS+ +LLAIA++R++T+F  ++ H  M+ RR
Sbjct: 111 PNTRRLTVSTWLLRQ------GLIDTSLTASVANLLAIAIERHITVF-RMQLHTRMSNRR 163

Query: 159 SGAIIAGIWAFCT-----------------GCGIVFILYSESTYVILCLISMFFAMLFLL 201
              +I  IW                      C  +  LYS+S  V   + ++      ++
Sbjct: 164 VVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNL--VTFVVM 221

Query: 202 VSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLM 261
           V LY H+F   R    R++         + T M    TV ++LG F +CW P  + L L 
Sbjct: 222 VVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLD 281

Query: 262 LSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCR 313
           + CPQ   C   +++   +L+L   NS M+P+IY++R +EM  TF++I+CC+
Sbjct: 282 VCCPQ---CD-VLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQ 329


>gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]
          Length = 364

 Score =  129 bits (323), Expect = 5e-30
 Identities = 84/292 (28%), Positives = 145/292 (49%), Gaps = 41/292 (14%)

Query: 44  LTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLL---- 99
           +T+ +  +L N+LV+ AI  N+  H P+Y+ + +LA AD    ++        YL+    
Sbjct: 57  ITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAY------FYLMFNTG 110

Query: 100 -NNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARR 158
            N + L ++   +R        +I  S+ AS+ +LLAIA++R++T+F  ++ H  M+ RR
Sbjct: 111 PNTRRLTVSTWLLRQ------GLIDTSLTASVANLLAIAIERHITVF-RMQLHTRMSNRR 163

Query: 159 SGAIIAGIWAFCT-----------------GCGIVFILYSESTYVILCLISMFFAMLFLL 201
              +I  IW                      C  +  LYS+S  V   + ++      ++
Sbjct: 164 VVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNL--VTFVVM 221

Query: 202 VSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLM 261
           V LY H+F   R    R++         + T M    TV ++LG F +CW P  + L L 
Sbjct: 222 VVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLD 281

Query: 262 LSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCR 313
           + CPQ   C   +++   +L+L   NS M+P+IY++R +EM  TF++I+CC+
Sbjct: 282 VCCPQ---CD-VLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQ 329


>gi|4885295 G protein-coupled receptor 12 [Homo sapiens]
          Length = 334

 Score =  118 bits (296), Expect = 6e-27
 Identities = 84/286 (29%), Positives = 143/286 (50%), Gaps = 33/286 (11%)

Query: 42  VFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNN 101
           V  T G +   EN +V+  I  N +L +PM+  + SLA+AD+L  +      +  YLL +
Sbjct: 50  VLCTSGTLISCENAIVVLIIFHNPSLRAPMFLLIGSLALADLLAGIGLITNFVFAYLLQS 109

Query: 102 KHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGA 161
           +   +          V   +I  S  AS+CSLLAI VDRY++++YAL YH   T   +  
Sbjct: 110 EATKL----------VTIGLIVASFSASVCSLLAITVDRYLSLYYALTYHSERTVTFTYV 159

Query: 162 IIAGIWAFCTGCGIVFI-----LYSESTYVIL--------CLISMFFAMLF-LLVSLYIH 207
           ++  +W      G++ +     L  EST  ++         ++S+ F  +F L++ LYI 
Sbjct: 160 MLVMLWGTSICLGLLPVMGWNCLRDESTCSVVRPLTKNNAAILSVSFLFMFALMLQLYIQ 219

Query: 208 MFLLARTHVKRIAALPG-ASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQ 266
           +  +   H  +IA      +++   T+ +G  T+ ++LG F  CW PF L+  +      
Sbjct: 220 ICKIVMRHAHQIALQHHFLATSHYVTTRKGVSTLAIILGTFAACWMPFTLYSLIADYTYP 279

Query: 267 NLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICC 312
           ++Y           L+    NS+++P+IYAFR+QE++K    +ICC
Sbjct: 280 SIYT-------YATLLPATYNSIINPVIYAFRNQEIQKALC-LICC 317


>gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]
          Length = 382

 Score =  117 bits (294), Expect = 1e-26
 Identities = 84/290 (28%), Positives = 143/290 (49%), Gaps = 31/290 (10%)

Query: 42  VFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNN 101
           VF+ +    +LENI V+  I K K  H PMY+F+ +LA++D+L  ++     +       
Sbjct: 51  VFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTY 110

Query: 102 KHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGA 161
           K L  A  F+R      +  + +++ AS+ SLLAIA++RY+T+   ++ H+     R   
Sbjct: 111 K-LTPAQWFLR------EGSMFVALSASVFSLLAIAIERYITML-KMKLHNGSNNFRLFL 162

Query: 162 IIAGIWAF-----------------CTGCGIVFILYSESTYVILCLISMFFAMLFLLVSL 204
           +I+  W                    + C  V  LY +  Y++ C  ++F  +L  +V L
Sbjct: 163 LISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKH-YILFC-TTVFTLLLLSIVIL 220

Query: 205 YIHMFLLARTHVKRIAALPGASSARQRTSMQGAV--TVTMLLGVFTVCWAPFFLHLTLML 262
           Y  ++ L RT  +R+      S A + +    A+  TV ++L VF  CWAP F+ L L +
Sbjct: 221 YCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDV 280

Query: 263 SCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICC 312
            C        F + +  +L+L + NS  +P+IY   ++EMR+ F  I+ C
Sbjct: 281 GCKVKTCDILFRAEY--FLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSC 328


>gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens]
          Length = 353

 Score =  116 bits (291), Expect = 2e-26
 Identities = 90/316 (28%), Positives = 157/316 (49%), Gaps = 48/316 (15%)

Query: 25  NVKNKSSPCEDMGIAVEVFLTLGVISLL----ENILVIGAIVKNKNLHSPMYFFVCSLAV 80
           N  N  +  +  G  + + L +G    L     N LVI A++KN+  H P Y+ + +LA 
Sbjct: 15  NRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAA 74

Query: 81  ADMLVSMSSAWETITIYLLNN-----KHLVIADAFVRHIDNVFDSMICISVVASMCSLLA 135
           AD    ++       ++L+ N     K L +   F+R    + DS    S+ AS+ +LL 
Sbjct: 75  ADFFAGIAY------VFLMFNTGPVSKTLTVNRWFLRQ--GLLDS----SLTASLTNLLV 122

Query: 136 IAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFC-----------------TGCGIVFI 178
           IAV+R+++I   +R H  +T +R   +I  +WA                   + C  +  
Sbjct: 123 IAVERHMSIM-RMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAP 181

Query: 179 LYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAV 238
           +YS S Y++   +S   A L ++V +Y+ +++  +     ++     S +R+RT M+   
Sbjct: 182 IYSRS-YLVFWTVSNLMAFLIMVV-VYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMK 239

Query: 239 TVTMLLGVFTVCWAPFFLHLTLM-LSCPQNLYCSRFMSHFNM-YLILIMCNSVMDPLIYA 296
           TV  +LG F VCW P  + L L  L+C Q   C   + H    +L+L + NSV++P+IY+
Sbjct: 240 TVMTVLGAFVVCWTPGLVVLLLDGLNCRQ---CG--VQHVKRWFLLLALLNSVVNPIIYS 294

Query: 297 FRSQEMRKTFKEIICC 312
           ++ ++M  T K++ICC
Sbjct: 295 YKDEDMYGTMKKMICC 310


>gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens]
          Length = 378

 Score =  115 bits (288), Expect = 5e-26
 Identities = 82/297 (27%), Positives = 148/297 (49%), Gaps = 38/297 (12%)

Query: 34  EDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWET 93
           E   +   +FL +    +LEN++V+ AI KN   H+ MYFF+ +LA+ D+L  ++     
Sbjct: 37  EGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIA---YK 93

Query: 94  ITIYLLNNKHLVIADA--FVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYH 151
           + I +   K   ++    F+R      +  + +++ AS CSLLAIA++R++T+   +R +
Sbjct: 94  VNILMSGKKTFSLSPTVWFLR------EGSMFVALGASTCSLLAIAIERHLTMI-KMRPY 146

Query: 152 HIMTARRSGAIIAGIW--AFCTG---------------CGIVFILYSESTYVILCLISMF 194
                 R   +I   W  AF  G               C  +  LYS+  Y+  C IS+F
Sbjct: 147 DANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKK-YIAFC-ISIF 204

Query: 195 FAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPF 254
            A+L  +V LY  ++ L ++  +++     A+      SM    TV +++ VF  CW+P 
Sbjct: 205 TAILVTIVILYARIYFLVKSSSRKV-----ANHNNSERSMALLRTVVIVVSVFIACWSPL 259

Query: 255 FLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIIC 311
           F+   + ++C   +     +     +++L + NS M+P+IY   S+EMR+ F  ++C
Sbjct: 260 FILFLIDVAC--RVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVC 314


>gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens]
          Length = 351

 Score =  114 bits (285), Expect = 1e-25
 Identities = 83/302 (27%), Positives = 145/302 (48%), Gaps = 42/302 (13%)

Query: 38  IAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIY 97
           + V + LT+ V+ LL N+LVI AI  N+  H P+Y+ + +LA AD+   ++       ++
Sbjct: 34  VVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVA------YLF 87

Query: 98  LL-----NNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHH 152
           L+         L +   F+R        ++  S+ AS+ +LLAIAV+R+ ++  A++ H 
Sbjct: 88  LMFHTGPRTARLSLEGWFLR------QGLLDTSLTASVATLLAIAVERHRSVM-AVQLHS 140

Query: 153 IMTARRSGAIIAGIWAFCTGCGI-----------------VFILYSESTYVILCLISMFF 195
            +   R   +I G+W    G G+                 +  L S S   +  L S+  
Sbjct: 141 RLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLL- 199

Query: 196 AMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFF 255
            +  L+V++Y  +F   R  V+R+A         + T++    TV ++LG F VCW P  
Sbjct: 200 -VFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQ 258

Query: 256 LHLTL-MLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRG 314
           + L L  L C         ++    +L+L   NS+++  +Y+ R  EMR+TF+ ++CC  
Sbjct: 259 VVLLLDGLGCES----CNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCAC 314

Query: 315 FR 316
            R
Sbjct: 315 LR 316


>gi|4885325 G protein-coupled receptor 3 [Homo sapiens]
          Length = 330

 Score =  113 bits (283), Expect = 2e-25
 Identities = 79/286 (27%), Positives = 136/286 (47%), Gaps = 42/286 (14%)

Query: 47  GVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVI 106
           G +   EN LV+  IV      +PM+  V SLAVAD+L  +        ++ + +  + +
Sbjct: 51  GTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGSAEMSL 110

Query: 107 ADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGI 166
                     V   ++ ++  AS+ SLLAI VDRY++++ AL Y+   T  R+  ++A +
Sbjct: 111 ----------VLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALV 160

Query: 167 WAFCTGCGIVFIL--------------YSESTYVILCLISMFFAMLFLLVSLYIHMFLLA 212
           W    G G++ +L              Y  S   ++ L   FF +  +++ LY  +  + 
Sbjct: 161 WGGALGLGLLPVLAWNCLDGLTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQICRIV 220

Query: 213 RTHVKRIA----ALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNL 268
             H ++IA     LP +     R   +G  T+ ++LG F  CW PF ++  L  +    L
Sbjct: 221 CRHAQQIALQRHLLPASHYVATR---KGIATLAVVLGAFAACWLPFTVYCLLGDAHSPPL 277

Query: 269 YCSRFMSHFNMYLILIMC--NSVMDPLIYAFRSQEMRKTFKEIICC 312
           Y          YL L+    NS+++P+IYAFR+Q+++K    + CC
Sbjct: 278 Y---------TYLTLLPATYNSMINPIIYAFRNQDVQKVLWAVCCC 314


>gi|5921992 adenosine A2a receptor [Homo sapiens]
          Length = 412

 Score =  113 bits (282), Expect = 3e-25
 Identities = 89/315 (28%), Positives = 149/315 (47%), Gaps = 49/315 (15%)

Query: 32  PCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAW 91
           P     + + V L + V+++L N+LV  A+  N NL +   +FV SLA AD+ V + +  
Sbjct: 2   PIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIP 61

Query: 92  ETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYH 151
             ITI                H        + +   +S+ SLLAIA+DRY+ I   LRY+
Sbjct: 62  FAITIST--------GFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYN 113

Query: 152 HIMTARRSGAIIAGIWAFC------------------------TGCGI--VFILYSESTY 185
            ++T  R+  IIA  W                            GCG   V  L+ +   
Sbjct: 114 GLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVP 173

Query: 186 VILCLISMFFAM----LFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQ----GA 237
           +   +   FFA     L L++ +Y+ +FL AR  +K++ + P     R R+++Q     A
Sbjct: 174 MNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQP-LPGERARSTLQKEVHAA 232

Query: 238 VTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMC--NSVMDPLIY 295
            ++ +++G+F +CW P  +       CP   +   ++    MYL +++   NSV++P IY
Sbjct: 233 KSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWL----MYLAIVLSHTNSVVNPFIY 288

Query: 296 AFRSQEMRKTFKEII 310
           A+R +E R+TF++II
Sbjct: 289 AYRIREFRQTFRKII 303


>gi|134244587 endothelial differentiation, sphingolipid
           G-protein-coupled receptor, 5 [Homo sapiens]
          Length = 353

 Score =  106 bits (265), Expect = 2e-23
 Identities = 84/326 (25%), Positives = 156/326 (47%), Gaps = 40/326 (12%)

Query: 4   SFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGAIVK 63
           S +  +L+ N      N +   ++ + +    +  A  V L   ++  +EN+LV+ A+ +
Sbjct: 3   SLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIV--VENLLVLIAVAR 60

Query: 64  NKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMIC 123
           N   HS MY F+ +LA +D+L  ++    T+    +  + L     F R      +    
Sbjct: 61  NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLR-LTPVQWFAR------EGSAF 113

Query: 124 ISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAF-------------C 170
           I++ AS+ SLLAIA++R+V I     Y    + R    +I   W               C
Sbjct: 114 ITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRML-LLIGASWLISLVLGGLPILGWNC 172

Query: 171 TG----CGIVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGAS 226
            G    C  V  LY++  + +LC++++F  +L  +V+LY+ ++ + R+    +AA    +
Sbjct: 173 LGHLEACSTVLPLYAK--HYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLA 230

Query: 227 SARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMC 286
             +         TVT++LGVF VCW P F  L L  +CP +     + +H+  +  +   
Sbjct: 231 LLK---------TVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHY--FFAVSTL 279

Query: 287 NSVMDPLIYAFRSQEMRKTFKEIICC 312
           NS+++P+IY +RS+++R+     + C
Sbjct: 280 NSLLNPVIYTWRSRDLRREVLRPLQC 305


>gi|4501951 adenosine A2b receptor [Homo sapiens]
          Length = 332

 Score =  103 bits (257), Expect = 2e-22
 Identities = 81/305 (26%), Positives = 141/305 (46%), Gaps = 44/305 (14%)

Query: 40  VEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLL 99
           V + L +  +S+  N+LV  A+     L +P  +F+ SLA AD+ V + +    ITI   
Sbjct: 11  VALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITI--- 67

Query: 100 NNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRS 159
               L     F   +       + +   +S+ SLLA+AVDRY+ I   LRY  ++T  R+
Sbjct: 68  ---SLGFCTDFYGCL--FLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRA 122

Query: 160 GAIIAGIWAFCTGCGIVFIL-------------------YSESTYVILCLISMFFAM--- 197
             +IA +W    G G+   L                    +ES  ++ CL      M   
Sbjct: 123 RGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYM 182

Query: 198 ------------LFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLG 245
                       L +++ +YI +FL+A   ++R   +  + +  QR  +  A ++ M++G
Sbjct: 183 VYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQR-EIHAAKSLAMIVG 241

Query: 246 VFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKT 305
           +F +CW P      + L  P     ++     NM ++L   NSV++P++YA+R+++ R T
Sbjct: 242 IFALCWLPVHAVNCVTLFQPAQ-GKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT 300

Query: 306 FKEII 310
           F +II
Sbjct: 301 FHKII 305


>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
          Length = 572

 Score =  101 bits (251), Expect = 1e-21
 Identities = 87/338 (25%), Positives = 152/338 (44%), Gaps = 74/338 (21%)

Query: 37  GIAVEVFLTLGVI-SLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETIT 95
           G+ V VFL   ++ ++  N+LVI ++  N++L +   +F+ +LAVAD+L+S +    + T
Sbjct: 96  GVGVGVFLAAFILMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSAT 155

Query: 96  IYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMT 155
           + +L         AF R   +V+ ++  +   AS+ SL  I+VDRYV + ++L+Y  IMT
Sbjct: 156 MEVLGFW------AFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMT 209

Query: 156 ARRSGAIIAGIWAFC-------------------TGCGIVFILYSESTYVILCLISMFFA 196
            R++ AI+A +W                        CGI      E+ Y +   +  F+ 
Sbjct: 210 ERKAAAILALLWVVALVVSVGPLLGWKEPVPPDERFCGIT----EEAGYAVFSSVCSFYL 265

Query: 197 MLFLLVSLYIHMFLLARTHVKRI---------------------AALPGASSARQRTSMQ 235
            + ++V +Y  ++++AR+  + +                      A  GA  A    S +
Sbjct: 266 PMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADGAHGMRSAK 325

Query: 236 G--------------------AVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMS 275
           G                    A T+ +++GVF +CW PFF  L L    PQ         
Sbjct: 326 GHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQ---LKPSEG 382

Query: 276 HFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCR 313
            F +   L   NS ++PLIY   S+E ++ F  ++ C+
Sbjct: 383 VFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQ 420


>gi|13540517 endothelial differentiation, sphingolipid
           G-protein-coupled receptor, 8 [Homo sapiens]
          Length = 398

 Score =  100 bits (248), Expect = 2e-21
 Identities = 81/302 (26%), Positives = 151/302 (50%), Gaps = 39/302 (12%)

Query: 37  GIAVEVFLTLGVIS--LLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETI 94
           G+  +  + L V +  +LEN+ V+  + ++   H+PM+  + SL ++D+L   + A   +
Sbjct: 35  GLRADAVVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANIL 94

Query: 95  TIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIM 154
               L  K L  A  F R      +  + +++ AS+ SLLAIA++R +T+  A R    +
Sbjct: 95  LSGPLTLK-LSPALWFAR------EGGVFVALTASVLSLLAIALERSLTM--ARRGPAPV 145

Query: 155 TAR-RSGAIIAGIWAF-------------CTG----CGIVFILYSESTYVILCLISMFFA 196
           ++R R+ A+ A  W               C G    C  V  LY+++ YV+ C+++ F  
Sbjct: 146 SSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKA-YVLFCVLA-FVG 203

Query: 197 MLFLLVSLYIHMFLLARTHVKRIAALPGASSA------RQRTSMQGAVTVTMLLGVFTVC 250
           +L  + +LY  ++   R + +R+ A PG +        R+  S+    T++++L  F  C
Sbjct: 204 ILAAICALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLALLRTLSVVLLAFVAC 263

Query: 251 WAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEII 310
           W P FL L L ++CP        +   + +L L M NS+++P+IY   ++++R     ++
Sbjct: 264 WGPLFLLLLLDVACPART--CPVLLQADPFLGLAMANSLLNPIIYTLTNRDLRHALLRLV 321

Query: 311 CC 312
           CC
Sbjct: 322 CC 323


>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
          Length = 520

 Score = 99.8 bits (247), Expect = 3e-21
 Identities = 89/380 (23%), Positives = 171/380 (45%), Gaps = 91/380 (23%)

Query: 2   NSSFHLHFLDLNLNATEGNLSGPNVKNKSS--PCEDMGIAVEVFLTLG---VISLLENIL 56
           N+S   H+ +L       N +GPN  + +S  P  D+  A+ V L LG   + +++ NIL
Sbjct: 10  NTSAPAHWGELK----NANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNIL 65

Query: 57  VIGAIVKNKNLHSPMYFFVCSLAVADMLVSM-----SSAWETITIYLLNNKHLVIADAFV 111
           VI ++  N++L +P  +F+ +LA+AD+L+S      S+A E +  ++L     +  D + 
Sbjct: 66  VILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGR---IFCDIWA 122

Query: 112 RHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCT 171
                  D + C + + S+C   AI++DRY+ + Y+L+Y  ++T R++   +  +W   T
Sbjct: 123 -----AVDVLCCTASILSLC---AISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLST 174

Query: 172 GCGIVFIL---------------YSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHV 216
              I  +L                 E  Y +   +  F+  L +++ +Y  ++++A+   
Sbjct: 175 VISIGPLLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTT 234

Query: 217 KRIAA--LPGASSARQRT------------------------------------SMQGAV 238
           K + A  +   S++++ T                                      + A 
Sbjct: 235 KNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAK 294

Query: 239 TVTMLLGVFTVCWAPFFLHLTL-----MLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPL 293
           T+ +++G+F +CW PFF+ L L      L  P  +        F +   L   NS ++P+
Sbjct: 295 TLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAV--------FKVVFWLGYFNSCLNPI 346

Query: 294 IYAFRSQEMRKTFKEIICCR 313
           IY   S+E ++ F  I+ C+
Sbjct: 347 IYPCSSKEFKRAFVRILGCQ 366


>gi|115305569 adenosine A1 receptor [Homo sapiens]
          Length = 326

 Score = 99.4 bits (246), Expect = 4e-21
 Identities = 89/303 (29%), Positives = 143/303 (47%), Gaps = 44/303 (14%)

Query: 38  IAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIY 97
           I +EV + L  +S+  N+LVI A+  N+ L    + F+ SLAVAD+ V        I + 
Sbjct: 13  IGIEVLIAL--VSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGAL----VIPLA 66

Query: 98  LLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTAR 157
           +L N    I      H   +    + I   +S+ +LLAIAVDRY+ +   LRY  ++T R
Sbjct: 67  ILIN----IGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPR 122

Query: 158 RSGAIIAGIW--AFCTGCGIVFILYSESTY-------------VILC----LISMFFAML 198
           R+   IAG W  +F  G   +F   + S               VI C    +ISM + + 
Sbjct: 123 RAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVY 182

Query: 199 F-----------LLVSLYIHMFLLARTHV-KRIAALPGASSARQRTSMQGAVTVTMLLGV 246
           F           L+V +Y+ +F L R  + K+++A  G         ++ A ++ ++L +
Sbjct: 183 FNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFL 242

Query: 247 FTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTF 306
           F + W P  +   + L CP    C +      + + L   NS M+P++YAFR Q+ R TF
Sbjct: 243 FALSWLPLHILNCITLFCPS---CHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTF 299

Query: 307 KEI 309
            +I
Sbjct: 300 LKI 302


>gi|4501947 adenosine A1 receptor [Homo sapiens]
          Length = 326

 Score = 99.4 bits (246), Expect = 4e-21
 Identities = 89/303 (29%), Positives = 143/303 (47%), Gaps = 44/303 (14%)

Query: 38  IAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIY 97
           I +EV + L  +S+  N+LVI A+  N+ L    + F+ SLAVAD+ V        I + 
Sbjct: 13  IGIEVLIAL--VSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGAL----VIPLA 66

Query: 98  LLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTAR 157
           +L N    I      H   +    + I   +S+ +LLAIAVDRY+ +   LRY  ++T R
Sbjct: 67  ILIN----IGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPR 122

Query: 158 RSGAIIAGIW--AFCTGCGIVFILYSESTY-------------VILC----LISMFFAML 198
           R+   IAG W  +F  G   +F   + S               VI C    +ISM + + 
Sbjct: 123 RAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVY 182

Query: 199 F-----------LLVSLYIHMFLLARTHV-KRIAALPGASSARQRTSMQGAVTVTMLLGV 246
           F           L+V +Y+ +F L R  + K+++A  G         ++ A ++ ++L +
Sbjct: 183 FNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFL 242

Query: 247 FTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTF 306
           F + W P  +   + L CP    C +      + + L   NS M+P++YAFR Q+ R TF
Sbjct: 243 FALSWLPLHILNCITLFCPS---CHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTF 299

Query: 307 KEI 309
            +I
Sbjct: 300 LKI 302


>gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score = 95.5 bits (236), Expect = 6e-20
 Identities = 82/318 (25%), Positives = 143/318 (44%), Gaps = 46/318 (14%)

Query: 31  SPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHS-PMYFFVCSLAVADMLVSMSS 89
           +P + + IAV + LTLG  ++LEN+LV+  I+ +++L   P Y F+ SLAVAD+L S+  
Sbjct: 112 NPSQQLAIAV-LSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIF 170

Query: 90  AWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALR 149
            +  I  ++ + K     + F+  +  V       S  AS+ SL   A+DRY++I   L 
Sbjct: 171 VYSFIDFHVFHRKDS--RNVFLFKLGGV-----TASFTASVGSLFLTAIDRYISIHRPLA 223

Query: 150 YHHIMTARRSGAIIAGIWAFCTGCGIVFIL----------------YSESTYVILCLISM 193
           Y  I+T  ++      +W       ++ +L                + + TY ++  I +
Sbjct: 224 YKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETY-LMFWIGV 282

Query: 194 FFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVT------------ 241
              +L  +V  Y+++   A +H  R+       S    TS  G V VT            
Sbjct: 283 TSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLA 342

Query: 242 ----MLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAF 297
               ++L V  +CW P    +   +    N       +  +M   L + NS ++P+IYA 
Sbjct: 343 KTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSM---LCLLNSTVNPIIYAL 399

Query: 298 RSQEMRKTFKEII-CCRG 314
           RS+++R  F+ +   C G
Sbjct: 400 RSKDLRHAFRSMFPSCEG 417


>gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score = 95.5 bits (236), Expect = 6e-20
 Identities = 82/318 (25%), Positives = 143/318 (44%), Gaps = 46/318 (14%)

Query: 31  SPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHS-PMYFFVCSLAVADMLVSMSS 89
           +P + + IAV + LTLG  ++LEN+LV+  I+ +++L   P Y F+ SLAVAD+L S+  
Sbjct: 112 NPSQQLAIAV-LSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIF 170

Query: 90  AWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALR 149
            +  I  ++ + K     + F+  +  V       S  AS+ SL   A+DRY++I   L 
Sbjct: 171 VYSFIDFHVFHRKDS--RNVFLFKLGGV-----TASFTASVGSLFLTAIDRYISIHRPLA 223

Query: 150 YHHIMTARRSGAIIAGIWAFCTGCGIVFIL----------------YSESTYVILCLISM 193
           Y  I+T  ++      +W       ++ +L                + + TY ++  I +
Sbjct: 224 YKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETY-LMFWIGV 282

Query: 194 FFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVT------------ 241
              +L  +V  Y+++   A +H  R+       S    TS  G V VT            
Sbjct: 283 TSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLA 342

Query: 242 ----MLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAF 297
               ++L V  +CW P    +   +    N       +  +M   L + NS ++P+IYA 
Sbjct: 343 KTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSM---LCLLNSTVNPIIYAL 399

Query: 298 RSQEMRKTFKEII-CCRG 314
           RS+++R  F+ +   C G
Sbjct: 400 RSKDLRHAFRSMFPSCEG 417


>gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score = 95.5 bits (236), Expect = 6e-20
 Identities = 82/318 (25%), Positives = 143/318 (44%), Gaps = 46/318 (14%)

Query: 31  SPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHS-PMYFFVCSLAVADMLVSMSS 89
           +P + + IAV + LTLG  ++LEN+LV+  I+ +++L   P Y F+ SLAVAD+L S+  
Sbjct: 112 NPSQQLAIAV-LSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIF 170

Query: 90  AWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALR 149
            +  I  ++ + K     + F+  +  V       S  AS+ SL   A+DRY++I   L 
Sbjct: 171 VYSFIDFHVFHRKDS--RNVFLFKLGGV-----TASFTASVGSLFLTAIDRYISIHRPLA 223

Query: 150 YHHIMTARRSGAIIAGIWAFCTGCGIVFIL----------------YSESTYVILCLISM 193
           Y  I+T  ++      +W       ++ +L                + + TY ++  I +
Sbjct: 224 YKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETY-LMFWIGV 282

Query: 194 FFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVT------------ 241
              +L  +V  Y+++   A +H  R+       S    TS  G V VT            
Sbjct: 283 TSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLA 342

Query: 242 ----MLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAF 297
               ++L V  +CW P    +   +    N       +  +M   L + NS ++P+IYA 
Sbjct: 343 KTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSM---LCLLNSTVNPIIYAL 399

Query: 298 RSQEMRKTFKEII-CCRG 314
           RS+++R  F+ +   C G
Sbjct: 400 RSKDLRHAFRSMFPSCEG 417


>gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score = 95.5 bits (236), Expect = 6e-20
 Identities = 82/318 (25%), Positives = 143/318 (44%), Gaps = 46/318 (14%)

Query: 31  SPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHS-PMYFFVCSLAVADMLVSMSS 89
           +P + + IAV + LTLG  ++LEN+LV+  I+ +++L   P Y F+ SLAVAD+L S+  
Sbjct: 112 NPSQQLAIAV-LSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIF 170

Query: 90  AWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALR 149
            +  I  ++ + K     + F+  +  V       S  AS+ SL   A+DRY++I   L 
Sbjct: 171 VYSFIDFHVFHRKDS--RNVFLFKLGGV-----TASFTASVGSLFLTAIDRYISIHRPLA 223

Query: 150 YHHIMTARRSGAIIAGIWAFCTGCGIVFIL----------------YSESTYVILCLISM 193
           Y  I+T  ++      +W       ++ +L                + + TY ++  I +
Sbjct: 224 YKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETY-LMFWIGV 282

Query: 194 FFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVT------------ 241
              +L  +V  Y+++   A +H  R+       S    TS  G V VT            
Sbjct: 283 TSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLA 342

Query: 242 ----MLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAF 297
               ++L V  +CW P    +   +    N       +  +M   L + NS ++P+IYA 
Sbjct: 343 KTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSM---LCLLNSTVNPIIYAL 399

Query: 298 RSQEMRKTFKEII-CCRG 314
           RS+++R  F+ +   C G
Sbjct: 400 RSKDLRHAFRSMFPSCEG 417


>gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score = 95.5 bits (236), Expect = 6e-20
 Identities = 82/318 (25%), Positives = 143/318 (44%), Gaps = 46/318 (14%)

Query: 31  SPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHS-PMYFFVCSLAVADMLVSMSS 89
           +P + + IAV + LTLG  ++LEN+LV+  I+ +++L   P Y F+ SLAVAD+L S+  
Sbjct: 112 NPSQQLAIAV-LSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIF 170

Query: 90  AWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALR 149
            +  I  ++ + K     + F+  +  V       S  AS+ SL   A+DRY++I   L 
Sbjct: 171 VYSFIDFHVFHRKDS--RNVFLFKLGGV-----TASFTASVGSLFLTAIDRYISIHRPLA 223

Query: 150 YHHIMTARRSGAIIAGIWAFCTGCGIVFIL----------------YSESTYVILCLISM 193
           Y  I+T  ++      +W       ++ +L                + + TY ++  I +
Sbjct: 224 YKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETY-LMFWIGV 282

Query: 194 FFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVT------------ 241
              +L  +V  Y+++   A +H  R+       S    TS  G V VT            
Sbjct: 283 TSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLA 342

Query: 242 ----MLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAF 297
               ++L V  +CW P    +   +    N       +  +M   L + NS ++P+IYA 
Sbjct: 343 KTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSM---LCLLNSTVNPIIYAL 399

Query: 298 RSQEMRKTFKEII-CCRG 314
           RS+++R  F+ +   C G
Sbjct: 400 RSKDLRHAFRSMFPSCEG 417


>gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]
          Length = 439

 Score = 95.5 bits (236), Expect = 6e-20
 Identities = 82/318 (25%), Positives = 143/318 (44%), Gaps = 46/318 (14%)

Query: 31  SPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHS-PMYFFVCSLAVADMLVSMSS 89
           +P + + IAV + LTLG  ++LEN+LV+  I+ +++L   P Y F+ SLAVAD+L S+  
Sbjct: 79  NPSQQLAIAV-LSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIF 137

Query: 90  AWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALR 149
            +  I  ++ + K     + F+  +  V       S  AS+ SL   A+DRY++I   L 
Sbjct: 138 VYSFIDFHVFHRKDS--RNVFLFKLGGV-----TASFTASVGSLFLTAIDRYISIHRPLA 190

Query: 150 YHHIMTARRSGAIIAGIWAFCTGCGIVFIL----------------YSESTYVILCLISM 193
           Y  I+T  ++      +W       ++ +L                + + TY ++  I +
Sbjct: 191 YKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETY-LMFWIGV 249

Query: 194 FFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVT------------ 241
              +L  +V  Y+++   A +H  R+       S    TS  G V VT            
Sbjct: 250 TSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLA 309

Query: 242 ----MLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAF 297
               ++L V  +CW P    +   +    N       +  +M   L + NS ++P+IYA 
Sbjct: 310 KTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSM---LCLLNSTVNPIIYAL 366

Query: 298 RSQEMRKTFKEII-CCRG 314
           RS+++R  F+ +   C G
Sbjct: 367 RSKDLRHAFRSMFPSCEG 384


>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
          Length = 455

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 88/364 (24%), Positives = 160/364 (43%), Gaps = 78/364 (21%)

Query: 12  LNLNATEG-NLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSP 70
           L+ NA++  N + P      S    +G+ +   +  GV+    NILVI ++  +++LHS 
Sbjct: 4   LSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLG---NILVILSVACHRHLHSV 60

Query: 71  MYFFVCSLAVADMLVS-----MSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICIS 125
            ++++ +LAVAD+L++      S+ +E +  +           AF R   N++ ++  + 
Sbjct: 61  THYYIVNLAVADLLLTSTVLPFSAIFEVLGYW-----------AFGRVFCNIWAAVDVLC 109

Query: 126 VVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGI---------- 175
             AS+  L  I++DRY+ + Y LRY  I+T RR    +  +WA      I          
Sbjct: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA 169

Query: 176 -----VFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLA------------------ 212
                +  +  E  YV+   +  F+  L +++ +Y  ++++A                  
Sbjct: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229

Query: 213 -----RTHVKRI-AALPGASSARQRT-----------SMQGAVTVTMLLGVFTVCWAPFF 255
                R H K   A   G +SA+ +T             + A T+ +++G F +CW PFF
Sbjct: 230 EQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFF 289

Query: 256 LHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRGF 315
           L + +    P         + F +   L   NS ++P+IY   SQE +K F+ ++     
Sbjct: 290 LVMPIGSFFPD---FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL----- 341

Query: 316 RIAC 319
           RI C
Sbjct: 342 RIQC 345


>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
          Length = 466

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 88/364 (24%), Positives = 160/364 (43%), Gaps = 78/364 (21%)

Query: 12  LNLNATEG-NLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSP 70
           L+ NA++  N + P      S    +G+ +   +  GV+    NILVI ++  +++LHS 
Sbjct: 4   LSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLG---NILVILSVACHRHLHSV 60

Query: 71  MYFFVCSLAVADMLVS-----MSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICIS 125
            ++++ +LAVAD+L++      S+ +E +  +           AF R   N++ ++  + 
Sbjct: 61  THYYIVNLAVADLLLTSTVLPFSAIFEVLGYW-----------AFGRVFCNIWAAVDVLC 109

Query: 126 VVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGI---------- 175
             AS+  L  I++DRY+ + Y LRY  I+T RR    +  +WA      I          
Sbjct: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA 169

Query: 176 -----VFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLA------------------ 212
                +  +  E  YV+   +  F+  L +++ +Y  ++++A                  
Sbjct: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229

Query: 213 -----RTHVKRI-AALPGASSARQRT-----------SMQGAVTVTMLLGVFTVCWAPFF 255
                R H K   A   G +SA+ +T             + A T+ +++G F +CW PFF
Sbjct: 230 EQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFF 289

Query: 256 LHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRGF 315
           L + +    P         + F +   L   NS ++P+IY   SQE +K F+ ++     
Sbjct: 290 LVMPIGSFFPD---FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL----- 341

Query: 316 RIAC 319
           RI C
Sbjct: 342 RIQC 345


>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
          Length = 475

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 88/364 (24%), Positives = 160/364 (43%), Gaps = 78/364 (21%)

Query: 12  LNLNATEG-NLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSP 70
           L+ NA++  N + P      S    +G+ +   +  GV+    NILVI ++  +++LHS 
Sbjct: 4   LSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLG---NILVILSVACHRHLHSV 60

Query: 71  MYFFVCSLAVADMLVS-----MSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICIS 125
            ++++ +LAVAD+L++      S+ +E +  +           AF R   N++ ++  + 
Sbjct: 61  THYYIVNLAVADLLLTSTVLPFSAIFEVLGYW-----------AFGRVFCNIWAAVDVLC 109

Query: 126 VVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGI---------- 175
             AS+  L  I++DRY+ + Y LRY  I+T RR    +  +WA      I          
Sbjct: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA 169

Query: 176 -----VFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLA------------------ 212
                +  +  E  YV+   +  F+  L +++ +Y  ++++A                  
Sbjct: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229

Query: 213 -----RTHVKRI-AALPGASSARQRT-----------SMQGAVTVTMLLGVFTVCWAPFF 255
                R H K   A   G +SA+ +T             + A T+ +++G F +CW PFF
Sbjct: 230 EQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFF 289

Query: 256 LHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRGF 315
           L + +    P         + F +   L   NS ++P+IY   SQE +K F+ ++     
Sbjct: 290 LVMPIGSFFPD---FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL----- 341

Query: 316 RIAC 319
           RI C
Sbjct: 342 RIQC 345


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.333    0.141    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,510,218
Number of Sequences: 37866
Number of extensions: 389358
Number of successful extensions: 3613
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 539
Number of HSP's successfully gapped in prelim test: 198
Number of HSP's that attempted gapping in prelim test: 1903
Number of HSP's gapped (non-prelim): 1010
length of query: 325
length of database: 18,247,518
effective HSP length: 102
effective length of query: 223
effective length of database: 14,385,186
effective search space: 3207896478
effective search space used: 3207896478
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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