Search of human proteins with 5174405

Search of human proteins with 5174405

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5174405 voltage-dependent calcium channel gamma-2 subunit
[Homo sapiens]
         (323 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Ho...   647   0.0  
gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Ho...   478   e-135
gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Ho...   376   e-104
gi|24586686 voltage-dependent calcium channel gamma-8 subunit [H...   342   3e-94
gi|22027551 voltage-dependent calcium channel gamma-5 subunit is...   120   2e-27
gi|21361975 voltage-dependent calcium channel gamma-7 subunit [H...   113   2e-25
gi|7656950 voltage-dependent calcium channel gamma-5 subunit iso...   108   8e-24
gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens]       57   3e-08
gi|226437592 transmembrane protein 114 [Homo sapiens]                  57   3e-08
gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo...    55   8e-08
gi|4502539 voltage-dependent calcium channel gamma-1 subunit [Ho...    45   7e-05
gi|169211272 PREDICTED: germ cell-specific gene 1-like protein 2...    39   0.006
gi|169211660 PREDICTED: germ cell-specific gene 1-like protein 2...    39   0.006
gi|169210878 PREDICTED: germ cell-specific gene 1-like protein 2...    39   0.006
gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2 ...    38   0.011
gi|239745400 PREDICTED: transmembrane protein 114 [Homo sapiens]       38   0.011
gi|4502877 claudin 4 [Homo sapiens]                                    38   0.014
gi|153792768 claudin 6 [Homo sapiens]                                  36   0.040
gi|47716519 claudin 20 [Homo sapiens]                                  35   0.069
gi|157951718 GSG1-like isoform 1 [Homo sapiens]                        35   0.069
gi|40788011 claudin 8 [Homo sapiens]                                   35   0.090
gi|11141861 claudin 9 [Homo sapiens]                                   34   0.15 
gi|7705961 claudin 18 isoform 1 [Homo sapiens]                         34   0.15 
gi|5921465 claudin 10 isoform b [Homo sapiens]                         34   0.20 
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    33   0.26 
gi|33598916 claudin 10 isoform a [Homo sapiens]                        33   0.26 
gi|4503559 epithelial membrane protein 1 [Homo sapiens]                33   0.34 
gi|5031949 natural killer cell group 7 sequence [Homo sapiens]         33   0.34 
gi|4505907 peripheral myelin protein 22 [Homo sapiens]                 33   0.45 
gi|24430165 peripheral myelin protein 22 [Homo sapiens]                33   0.45 

>gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Homo
           sapiens]
          Length = 323

 Score =  647 bits (1668), Expect = 0.0
 Identities = 323/323 (100%), Positives = 323/323 (100%)

Query: 1   MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTH 60
           MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTH
Sbjct: 1   MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTH 60

Query: 61  SGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGL 120
           SGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGL
Sbjct: 61  SGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGL 120

Query: 121 CIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDPSKSDSKKNSYSYGWSF 180
           CIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDPSKSDSKKNSYSYGWSF
Sbjct: 121 CIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDPSKSDSKKNSYSYGWSF 180

Query: 181 YFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQASAITRIPSYRYRYQRRSRSS 240
           YFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQASAITRIPSYRYRYQRRSRSS
Sbjct: 181 YFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQASAITRIPSYRYRYQRRSRSS 240

Query: 241 SRSTEPSHSRDASPVGIKGFNTLPSTEISMYTLSRDPLKAATTPTATYNSDRDNSFLQVH 300
           SRSTEPSHSRDASPVGIKGFNTLPSTEISMYTLSRDPLKAATTPTATYNSDRDNSFLQVH
Sbjct: 241 SRSTEPSHSRDASPVGIKGFNTLPSTEISMYTLSRDPLKAATTPTATYNSDRDNSFLQVH 300

Query: 301 NCIQKENKDSLHSNTANRRTTPV 323
           NCIQKENKDSLHSNTANRRTTPV
Sbjct: 301 NCIQKENKDSLHSNTANRRTTPV 323


>gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Homo
           sapiens]
          Length = 315

 Score =  478 bits (1230), Expect = e-135
 Identities = 241/323 (74%), Positives = 281/323 (86%), Gaps = 8/323 (2%)

Query: 1   MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTH 60
           M + DRG+QML+TTVGAFAAFSLMTIAVGTDYWLYSRGVC+TKS S+NETS+KNEEVMTH
Sbjct: 1   MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEEVMTH 60

Query: 61  SGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGL 120
           SGLWRTCCLEG F+G+CK+IDHFPEDADYE DTAEY LRAVRASS+FPILSV LLF GGL
Sbjct: 61  SGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFGGL 120

Query: 121 CIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDPSKSDSKKNSYSYGWSF 180
           C+AASEF+++RHN+ILSAGIFFVSAGLSNIIGIIVYISANAGDP + DSKK SYSYGWSF
Sbjct: 121 CVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSKK-SYSYGWSF 179

Query: 181 YFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQASAITRIPSYRYRYQRRSRSS 240
           YFGA SFIIAE+VGV+AVH++I++H+QLRA +  +++L+ S   R+P YRYR++R  RSS
Sbjct: 180 YFGAFSFIIAEIVGVVAVHIYIEKHQQLRAKSH-SEFLKKSTFARLPPYRYRFRR--RSS 236

Query: 241 SRSTEPSHSRDASPVGIKGFNTLPSTEISMYTLSRDPLKAATTPTATYNSDRDNSFLQVH 300
           SRSTEP  SRD SP+  KGF+T+PST+ISM+TLSRDP K   T     NSDRD++FLQ H
Sbjct: 237 SRSTEP-RSRDLSPIS-KGFHTIPSTDISMFTLSRDPSK--ITMGTLLNSDRDHAFLQFH 292

Query: 301 NCIQKENKDSLHSNTANRRTTPV 323
           N   KE K+SLH+N ANRRTTPV
Sbjct: 293 NSTPKEFKESLHNNPANRRTTPV 315


>gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Homo
           sapiens]
          Length = 327

 Score =  376 bits (966), Expect = e-104
 Identities = 194/327 (59%), Positives = 251/327 (76%), Gaps = 12/327 (3%)

Query: 5   DRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRG-VCKTKSVSENE--TSKKNEEVMTHS 61
           DRG+QMLLTT GAFAAFSLM IA+GTDYWLYS   +C   +++ ++    ++    +THS
Sbjct: 5   DRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGDLTHS 64

Query: 62  GLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGLC 121
           GLWR CC+EG +KG C +I+HFPED DY+ D++EY LR VRASS+FPILS ILL +GGLC
Sbjct: 65  GLWRVCCIEGIYKGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLLGGLC 124

Query: 122 IAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDPS--KSDSKKNSYSYGWS 179
           I A   Y  ++NI+LSAGI FV+AGLSNIIGIIVYIS+N GDPS  + + KKN Y+YGWS
Sbjct: 125 IGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYNYGWS 184

Query: 180 FYFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQASA---ITRIPSYRYRYQRR 236
           FYFGALSFI+AE VGVLAV+++I+++K+LR   +  ++L+AS+     R+PSYRYR +RR
Sbjct: 185 FYFGALSFIVAETVGVLAVNIYIEKNKELRFKTK-REFLKASSSSPYARMPSYRYR-RRR 242

Query: 237 SRSSSRSTEPSHSRDASPVGIKGFNTLPSTEISMYTLSRDPLKAATTPTATYNSDRDNSF 296
           SRSSSRSTE S SRD SP+G+K    +P  E+SMYTLSR+PLK  T   A+Y+ D++ SF
Sbjct: 243 SRSSSRSTEASPSRDVSPMGLKITGAIPMGELSMYTLSREPLKVTT--AASYSPDQEASF 300

Query: 297 LQVHNCIQKENKDSLHSNTANRRTTPV 323
           LQVH+  Q++ K+  H +  NRRTTPV
Sbjct: 301 LQVHDFFQQDLKEGFHVSMLNRRTTPV 327


>gi|24586686 voltage-dependent calcium channel gamma-8 subunit [Homo
           sapiens]
          Length = 425

 Score =  342 bits (876), Expect = 3e-94
 Identities = 180/304 (59%), Positives = 226/304 (74%), Gaps = 29/304 (9%)

Query: 5   DRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRG-VCKTKSVSEN------------ETS 51
           ++GVQ+LLTTVGAFAAF LMTIA+ TDYWLY+R  +C T +++               + 
Sbjct: 16  EKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGASE 75

Query: 52  KKNEEVMTHSGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILS 111
           KK+   +THSGLWR CCLEG  +G+C +I+HFPED DY+ D+AEY LR VRASSIFPILS
Sbjct: 76  KKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPEDTDYDHDSAEYLLRVVRASSIFPILS 135

Query: 112 VILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGD--PSKSDS 169
            ILL +GG+C+AAS  YK++ NIIL AGI FV+AGLSNIIG+IVYISANAG+  P + + 
Sbjct: 136 AILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGPKRDEE 195

Query: 170 KKNSYSYGWSFYFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQA--------- 220
           KKN YSYGWSFYFG LSFI+AE++GVLAV+++I+R ++    +R +D L+A         
Sbjct: 196 KKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSR-SDLLKAGGGAGGSGG 254

Query: 221 ---SAITRIPSYRYRYQRRSRSSSRSTEPSHSRDASPVGIKGFNTLPSTEISMYTLSRDP 277
              SAI R+PSYR+RY+RRSRSSSRS+EPS SRDASP G  G     ST+ISMYTLSRDP
Sbjct: 255 SGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGG-PGGPGFASTDISMYTLSRDP 313

Query: 278 LKAA 281
            K +
Sbjct: 314 SKGS 317


>gi|22027551 voltage-dependent calcium channel gamma-5 subunit
           isoform a [Homo sapiens]
          Length = 275

 Score =  120 bits (301), Expect = 2e-27
 Identities = 69/210 (32%), Positives = 119/210 (56%), Gaps = 11/210 (5%)

Query: 1   MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLY-SRGVCKTKSVSENETSKKNEEVMT 59
           M    R    LL++V A     L+ IAV TDYWLY   GV     V +N++++   ++  
Sbjct: 1   MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVI----VPQNQSTEI--KMSL 54

Query: 60  HSGLWRTCCLEGNFKGLCKQIDH-FPEDADYEADTAEYFLRAVRASSIFPILSVILLFMG 118
           HSGLWR C L G  +G C  I++  P +    +++    L+ +R+++ FP++S+  +F+G
Sbjct: 55  HSGLWRVCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIG 114

Query: 119 GLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISA---NAGDPSKSDSKKNSYS 175
            +          R  +   +GIFF+ +GLS ++G+++YIS+      + +K      +Y 
Sbjct: 115 FILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYK 174

Query: 176 YGWSFYFGALSFIIAEMVGVLAVHMFIDRH 205
           YGWSF F A+SF++ E  GV++V++F+ R+
Sbjct: 175 YGWSFAFAAISFLLTESAGVMSVYLFMKRY 204


>gi|21361975 voltage-dependent calcium channel gamma-7 subunit [Homo
           sapiens]
          Length = 275

 Score =  113 bits (283), Expect = 2e-25
 Identities = 67/202 (33%), Positives = 113/202 (55%), Gaps = 11/202 (5%)

Query: 11  LLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTHSGLWRTCCLE 70
           LL++V       L+ IAV TDYWLY     +   + +N+T++   ++  H+GLWR C   
Sbjct: 11  LLSSVFGACGLLLVGIAVSTDYWLYME---EGTVLPQNQTTEV--KMALHAGLWRVCFFA 65

Query: 71  GNFKGLCKQIDHFPE-DADYEADTAEYFLRAVRASSIFPILSVILLFMGGLCIAASEFYK 129
           G  KG C   ++F E + +   +  E  L+ VR ++ FP++S+ L+F   +         
Sbjct: 66  GREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIGHIRP 125

Query: 130 TRHNIILSAGIFFVSAGLSNIIGIIVYISANAGD----PSKSDSKKNSYSYGWSFYFGAL 185
            R  +   +GIFF+ +GLS ++G+++YIS+   +    PS S+   + Y YGWSF F A 
Sbjct: 126 QRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFH-YRYGWSFAFAAS 184

Query: 186 SFIIAEMVGVLAVHMFIDRHKQ 207
           SF++ E  GV++V++F  R+ +
Sbjct: 185 SFLLKEGAGVMSVYLFTKRYAE 206


>gi|7656950 voltage-dependent calcium channel gamma-5 subunit
           isoform b [Homo sapiens]
          Length = 296

 Score =  108 bits (269), Expect = 8e-24
 Identities = 64/197 (32%), Positives = 109/197 (55%), Gaps = 11/197 (5%)

Query: 1   MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLY-SRGVCKTKSVSENETSKKNEEVMT 59
           M    R    LL++V A     L+ IAV TDYWLY   GV     V +N++++   ++  
Sbjct: 1   MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVI----VPQNQSTEI--KMSL 54

Query: 60  HSGLWRTCCLEGNFKGLCKQIDH-FPEDADYEADTAEYFLRAVRASSIFPILSVILLFMG 118
           HSGLWR C L G  +G C  I++  P +    +++    L+ +R+++ FP++S+  +F+G
Sbjct: 55  HSGLWRVCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIG 114

Query: 119 GLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISA---NAGDPSKSDSKKNSYS 175
            +          R  +   +GIFF+ +GLS ++G+++YIS+      + +K      +Y 
Sbjct: 115 FILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYK 174

Query: 176 YGWSFYFGALSFIIAEM 192
           YGWSF F A+SF++ E+
Sbjct: 175 YGWSFAFAAISFLLTEV 191


>gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens]
          Length = 223

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 50/189 (26%), Positives = 88/189 (46%), Gaps = 18/189 (9%)

Query: 20  AFSLMTIAVGTDYW--LYSRGVCKTKSVSENETSKKN----EEVMTHSGLWRTCCLEGNF 73
           +F L+  A+GTD+W  + +  + +T   +++     N    E + +HSGLWRTC ++   
Sbjct: 19  SFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTCRVQSPC 78

Query: 74  KGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGLCIAASEFYKTRHN 133
             L   ++ F  +    ++++   L       I   LS+IL+  GG+    S F    + 
Sbjct: 79  TPL---MNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS-FLLQAYL 134

Query: 134 IILSAGIFFVSAGLSNIIGIIVYISANAGD--------PSKSDSKKNSYSYGWSFYFGAL 185
           ++L  GI F+   +  + GI VYI+ +A            K+   +   S+GWS   G +
Sbjct: 135 LLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFGWSLALGWI 194

Query: 186 SFIIAEMVG 194
           SFI   + G
Sbjct: 195 SFIAELLTG 203


>gi|226437592 transmembrane protein 114 [Homo sapiens]
          Length = 223

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 50/189 (26%), Positives = 88/189 (46%), Gaps = 18/189 (9%)

Query: 20  AFSLMTIAVGTDYW--LYSRGVCKTKSVSENETSKKN----EEVMTHSGLWRTCCLEGNF 73
           +F L+  A+GTD+W  + +  + +T   +++     N    E + +HSGLWRTC ++   
Sbjct: 19  SFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTCRVQSPC 78

Query: 74  KGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGLCIAASEFYKTRHN 133
             L   ++ F  +    ++++   L       I   LS+IL+  GG+    S F    + 
Sbjct: 79  TPL---MNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS-FLLQAYL 134

Query: 134 IILSAGIFFVSAGLSNIIGIIVYISANAGD--------PSKSDSKKNSYSYGWSFYFGAL 185
           ++L  GI F+   +  + GI VYI+ +A            K+   +   S+GWS   G +
Sbjct: 135 LLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFGWSLALGWI 194

Query: 186 SFIIAEMVG 194
           SFI   + G
Sbjct: 195 SFIAELLTG 203


>gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo
           sapiens]
          Length = 217

 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 49/189 (25%), Positives = 88/189 (46%), Gaps = 18/189 (9%)

Query: 20  AFSLMTIAVGTDYW--LYSRGVCKTKSVSENETSKKN----EEVMTHSGLWRTCCLEGNF 73
           +F L+  A+GT++W  + +  + +T   +++     N    E + +HSGLWRTC ++   
Sbjct: 13  SFVLLAAAIGTEFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTCRVQSPC 72

Query: 74  KGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGLCIAASEFYKTRHN 133
             L   ++ F  +    ++++   L       I   LS+IL+  GG+    S F    + 
Sbjct: 73  TPL---MNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS-FLLQAYL 128

Query: 134 IILSAGIFFVSAGLSNIIGIIVYISANAGD--------PSKSDSKKNSYSYGWSFYFGAL 185
           ++L  GI F+   +  + GI VYI+ +A            K+   +   S+GWS   G +
Sbjct: 129 LLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFGWSLALGWI 188

Query: 186 SFIIAEMVG 194
           SFI   + G
Sbjct: 189 SFIAELLTG 197


>gi|4502539 voltage-dependent calcium channel gamma-1 subunit [Homo
           sapiens]
          Length = 222

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 54/210 (25%), Positives = 84/210 (40%), Gaps = 30/210 (14%)

Query: 8   VQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTHSGLWRTC 67
           +++ +T     A   L   AV TD+W     V        N T +       H GLWR C
Sbjct: 7   LKVRVTLFCILAGIVLAMTAVVTDHW----AVLSPHMEHHNTTCEA-----AHFGLWRIC 57

Query: 68  -----------CLEGNFKGL--CKQIDHF-PEDAD--YEADTAEYFLRAVRASSIFPILS 111
                      C      G   C    HF P ++   +E  T + +  +  A +IF +  
Sbjct: 58  TKRIPMDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGF 117

Query: 112 VILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDPSKSDSKK 171
           +IL   G LC+  S   K R  ++  A +F+  AGL  ++ + V   +        D+  
Sbjct: 118 IIL---GSLCVLLS-LGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMIDSEDTVW 173

Query: 172 NSYSYGWSFYFGALSFIIAEMVGVLAVHMF 201
             Y Y WSF     +FI+   +G LA+ +F
Sbjct: 174 IEYYYSWSFACACAAFILL-FLGGLALLLF 202


>gi|169211272 PREDICTED: germ cell-specific gene 1-like protein
           2-like [Homo sapiens]
          Length = 293

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 37/147 (25%), Positives = 62/147 (42%), Gaps = 12/147 (8%)

Query: 60  HSGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGG 119
           H GLW++C  E +  G  ++   F      E     +         I  IL+  +L    
Sbjct: 89  HVGLWQSC--EESLNGEDEKCRSFRSVVPAEEQGVLWLSIGGEVLDIVLILTSAILLGSR 146

Query: 120 LCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVY-----ISANAGDPSKSDSKKNSY 174
           +   +  F+  R + +++  IF V AGL  ++  ++Y     I+ N G     D K  ++
Sbjct: 147 VSCRSPGFHWLRVDALVA--IFMVLAGLLGMVAHMMYTTIFQITVNLGP---EDWKPQTW 201

Query: 175 SYGWSFYFGALSFIIAEMVGVLAVHMF 201
            YGWS+     SF +   V V A+  F
Sbjct: 202 DYGWSYCLAWGSFALCLAVSVSAMSRF 228


>gi|169211660 PREDICTED: germ cell-specific gene 1-like protein
           2-like [Homo sapiens]
          Length = 293

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 37/147 (25%), Positives = 62/147 (42%), Gaps = 12/147 (8%)

Query: 60  HSGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGG 119
           H GLW++C  E +  G  ++   F      E     +         I  IL+  +L    
Sbjct: 89  HVGLWQSC--EESLNGEDEKCRSFRSVVPAEEQGVLWLSIGGEVLDIVLILTSAILLGSR 146

Query: 120 LCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVY-----ISANAGDPSKSDSKKNSY 174
           +   +  F+  R + +++  IF V AGL  ++  ++Y     I+ N G     D K  ++
Sbjct: 147 VSCRSPGFHWLRVDALVA--IFMVLAGLLGMVAHMMYTTIFQITVNLGP---EDWKPQTW 201

Query: 175 SYGWSFYFGALSFIIAEMVGVLAVHMF 201
            YGWS+     SF +   V V A+  F
Sbjct: 202 DYGWSYCLAWGSFALCLAVSVSAMSRF 228


>gi|169210878 PREDICTED: germ cell-specific gene 1-like protein
           2-like [Homo sapiens]
          Length = 293

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 37/147 (25%), Positives = 62/147 (42%), Gaps = 12/147 (8%)

Query: 60  HSGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGG 119
           H GLW++C  E +  G  ++   F      E     +         I  IL+  +L    
Sbjct: 89  HVGLWQSC--EESLNGEDEKCRSFRSVVPAEEQGVLWLSIGGEVLDIVLILTSAILLGSR 146

Query: 120 LCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVY-----ISANAGDPSKSDSKKNSY 174
           +   +  F+  R + +++  IF V AGL  ++  ++Y     I+ N G     D K  ++
Sbjct: 147 VSCRSPGFHWLRVDALVA--IFMVLAGLLGMVAHMMYTTIFQITVNLGP---EDWKPQTW 201

Query: 175 SYGWSFYFGALSFIIAEMVGVLAVHMF 201
            YGWS+     SF +   V V A+  F
Sbjct: 202 DYGWSYCLAWGSFALCLAVSVSAMSRF 228


>gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2
           [Homo sapiens]
          Length = 173

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 39/179 (21%), Positives = 67/179 (37%), Gaps = 35/179 (19%)

Query: 17  AFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTHSGLWRTCCLEGNFKGL 76
           A+    L+ +A+ TD+W+  R                      H GLWR C   GN    
Sbjct: 12  AWVGTILLVVAMATDHWMQYR----------------LSGSFAHQGLWRYCL--GN---- 49

Query: 77  CKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGLCIAASEFYKTRHNIIL 136
                        + D+  Y+  A RA  I   L  I   + G+   A +   +R +   
Sbjct: 50  ---------KCYLQTDSIAYW-NATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPF 99

Query: 137 SAGIFFVSAGLSNIIGIIVYISANAGDPSKSDSKKNSYSYGWSFYFGALSFIIAEMVGV 195
           SAGI F S+ L  ++ + +Y        S    +   + + WS+  G ++ ++    G+
Sbjct: 100 SAGIMFFSSTLFVVLALAIYTGVTV---SFLGRRFGDWRFSWSYILGWVAVLMTFFAGI 155


>gi|239745400 PREDICTED: transmembrane protein 114 [Homo sapiens]
          Length = 122

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 9/93 (9%)

Query: 110 LSVILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGD------ 163
           LS+IL+  GG+    S F    + ++L  GI F+   +  + GI VYI+ +A        
Sbjct: 11  LSLILMVFGGMTGFLS-FLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALC 69

Query: 164 --PSKSDSKKNSYSYGWSFYFGALSFIIAEMVG 194
               K+   +   S+GWS   G +SFI   + G
Sbjct: 70  LLEEKALLDQVDISFGWSLALGWISFIAELLTG 102


>gi|4502877 claudin 4 [Homo sapiens]
          Length = 209

 Score = 37.7 bits (86), Expect = 0.014
 Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 18/99 (18%)

Query: 62  GLWRTCCLEGNFKGLCKQIDHF---PEDADYEADTAEYFLRAVRASSIFPI----LSVIL 114
           GLW  C ++   +  CK  D     P+D           L+A RA  I  I    L V+L
Sbjct: 49  GLWMNCVVQSTGQMQCKVYDSLLALPQD-----------LQAARALVIISIIVAALGVLL 97

Query: 115 LFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGI 153
             +GG C    E    +   ++ AG+ F+ AGL  I+ +
Sbjct: 98  SVVGGKCTNCLEDESAKAKTMIVAGVVFLLAGLMVIVPV 136


>gi|153792768 claudin 6 [Homo sapiens]
          Length = 220

 Score = 36.2 bits (82), Expect = 0.040
 Identities = 32/132 (24%), Positives = 57/132 (43%), Gaps = 23/132 (17%)

Query: 62  GLWRTCCLEGNFKGLCKQIDH---FPEDADYEADTAEYFLRAVRASSIFPIL----SVIL 114
           GLW +C ++   +  CK  D     P+D           L+A RA  +  +L     +++
Sbjct: 49  GLWMSCVVQSTGQMQCKVYDSLLALPQD-----------LQAARALCVIALLVALFGLLV 97

Query: 115 LFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGD---PSKSDSKK 171
              G  C    E   ++  ++L++GI FV +G+  +I +     A   D   P  ++++K
Sbjct: 98  YLAGAKCTTCVEEKDSKARLVLTSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQK 157

Query: 172 NSYSYGWSFYFG 183
                G S Y G
Sbjct: 158 R--ELGASLYLG 167


>gi|47716519 claudin 20 [Homo sapiens]
          Length = 219

 Score = 35.4 bits (80), Expect = 0.069
 Identities = 26/107 (24%), Positives = 51/107 (47%), Gaps = 5/107 (4%)

Query: 106 IFPILSVILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVY---ISANAG 162
           +   L +    +G  C       +T+ +   + G+ F+SAG+S++I  + Y   I AN  
Sbjct: 89  VLSALGICTSTVGMKCTRLGGDRETKSHASFAGGVCFMSAGISSLISTVWYTKEIIANFL 148

Query: 163 DPSKSDSKKNSYSYGWSFYFGALSFIIAEMVGVLAVHMFIDRHKQLR 209
           D +  +S  N +  G + Y G +S ++  + G++     I R+ + R
Sbjct: 149 DLTVPES--NKHEPGGAIYIGFISAMLLFISGMIFCTSCIKRNPEAR 193


>gi|157951718 GSG1-like isoform 1 [Homo sapiens]
          Length = 331

 Score = 35.4 bits (80), Expect = 0.069
 Identities = 37/160 (23%), Positives = 64/160 (40%), Gaps = 21/160 (13%)

Query: 60  HSGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGG 119
           H+G+W +C  E    GL ++   F        D A    + V   S+   +  ILL + G
Sbjct: 102 HTGIWYSC--EEELSGLGEKCRSF-------IDLAPASEKGVLWLSVVSEVLYILLLVVG 152

Query: 120 LCIAASEFYKTRH-----NIILSAGIFFVSAGLSNIIGIIVYISANAGDPS--KSDSKKN 172
             +   E + + +      +   A +F V +GL  ++  ++Y        S    D + +
Sbjct: 153 FSLMCLELFHSSNVIDGLKLNAFAAVFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRPH 212

Query: 173 SYSYGWSFYFGALSFIIAEMVGVLAVHMFID-----RHKQ 207
           S+ YGWSF     SF       V  ++ +       RHK+
Sbjct: 213 SWDYGWSFCLAWGSFTCCMAASVTTLNSYTKTVIEFRHKR 252


>gi|40788011 claudin 8 [Homo sapiens]
          Length = 225

 Score = 35.0 bits (79), Expect = 0.090
 Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 7/94 (7%)

Query: 62  GLWRTCCLEGNFKGLCKQIDH-FPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGL 120
           GLW  C  + N +  CK  D       D +A         + A+S+   L+ ++  +G  
Sbjct: 49  GLWMNCVRQANIRMQCKIYDSLLALSPDLQAARG-----LMCAASVMSFLAFMMAILGMK 103

Query: 121 CI-AASEFYKTRHNIILSAGIFFVSAGLSNIIGI 153
           C     +  K + +I+L+AGI F+  G+  +I +
Sbjct: 104 CTRCTGDNEKVKAHILLTAGIIFIITGMVVLIPV 137


>gi|11141861 claudin 9 [Homo sapiens]
          Length = 217

 Score = 34.3 bits (77), Expect = 0.15
 Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 18/99 (18%)

Query: 62  GLWRTCCLEGNFKGLCKQIDHF---PEDADYEADTAEYFLRAVRA----SSIFPILSVIL 114
           GLW +C ++   +  CK  D     P+D           L+A RA    + +  +L +++
Sbjct: 49  GLWMSCVVQSTGQMQCKVYDSLLALPQD-----------LQAARALCVIALLLALLGLLV 97

Query: 115 LFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGI 153
              G  C    E    +  I+L+AG+  + AG+  +I +
Sbjct: 98  AITGAQCTTCVEDEGAKARIVLTAGVILLLAGILVLIPV 136


>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
          Length = 261

 Score = 34.3 bits (77), Expect = 0.15
 Identities = 39/155 (25%), Positives = 63/155 (40%), Gaps = 30/155 (19%)

Query: 8   VQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTHSGLWRTC 67
           V  LL+ +G     +    A G D W        T+ + +N  +     V  + GLWR+C
Sbjct: 9   VAFLLSILGLAGCIA----ATGMDMW-------STQDLYDNPVTS----VFQYEGLWRSC 53

Query: 68  CLEGNFKGLCKQIDHFPEDADYEADTA-EYFLRAVRASSIFPI----LSVILLFMGGLCI 122
                     +Q   F E   Y         L+AVRA  I  I    + +++      CI
Sbjct: 54  V---------RQSSGFTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCI 104

Query: 123 AASEFYKT-RHNIILSAGIFFVSAGLSNIIGIIVY 156
                  + + N+ L++GI F+ +GL  I G+ V+
Sbjct: 105 RIGSMEDSAKANMTLTSGIMFIVSGLCAIAGVSVF 139


>gi|5921465 claudin 10 isoform b [Homo sapiens]
          Length = 228

 Score = 33.9 bits (76), Expect = 0.20
 Identities = 45/194 (23%), Positives = 71/194 (36%), Gaps = 20/194 (10%)

Query: 61  SGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGL 120
           + LW+ C  +      CK    FP     +          + A S+    S+  LF G  
Sbjct: 47  ANLWKACVTDSTGVSNCKD---FPSMLALDGYIQACRGLMIAAVSLGFFGSIFALF-GMK 102

Query: 121 CIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVY---ISANAGDPSKSDSKKNSYSYG 177
           C       K +  I   AGI F+ +GL ++ G  +Y   I+    DP   + K   Y  G
Sbjct: 103 CTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQK---YELG 159

Query: 178 WSFYFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQASAITRIPSYRYRYQRRS 237
            + + G     +  + GV+      D +K  R T         +  T + S R +Y    
Sbjct: 160 AALFIGWAGASLCIIGGVIFCFSISDNNKTPRYT--------YNGATSVMSSRTKY--HG 209

Query: 238 RSSSRSTEPSHSRD 251
               ++T PS   D
Sbjct: 210 GEDFKTTNPSKQFD 223


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 33.5 bits (75), Expect = 0.26
 Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 7/76 (9%)

Query: 220 ASAITRIPSYRYRYQRRSRSSSRSTEPSHSRDASPVGIKGFNTLPSTEISMYTLSRDPLK 279
           A A  +I + +      S SSS S++ S    A+    K   T+P  ++    +++ P+K
Sbjct: 203 ARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKK---TVPKKQV----VAKAPVK 255

Query: 280 AATTPTATYNSDRDNS 295
           AATTPT   +S  D+S
Sbjct: 256 AATTPTRKSSSSEDSS 271


>gi|33598916 claudin 10 isoform a [Homo sapiens]
          Length = 226

 Score = 33.5 bits (75), Expect = 0.26
 Identities = 50/197 (25%), Positives = 74/197 (37%), Gaps = 24/197 (12%)

Query: 60  HSGLWRTCCLEGNFKGLCKQIDHFP--EDADYEADTAEYFLRAVRASSIFPILSVILLFM 117
           + GLW  C   GN  G      HF   + A Y        + AV   S+    S+  LF 
Sbjct: 44  YQGLWMNCA--GNALGSFHCRPHFTIFKVAGYIQACRGLMIAAV---SLGFFGSIFALF- 97

Query: 118 GGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVY---ISANAGDPSKSDSKKNSY 174
           G  C       K +  I   AGI F+ +GL ++ G  +Y   I+    DP   + K   Y
Sbjct: 98  GMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQK---Y 154

Query: 175 SYGWSFYFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQASAITRIPSYRYRYQ 234
             G + + G     +  + GV+      D +K  R T         +  T + S R +Y 
Sbjct: 155 ELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRYT--------YNGATSVMSSRTKY- 205

Query: 235 RRSRSSSRSTEPSHSRD 251
                  ++T PS   D
Sbjct: 206 -HGGEDFKTTNPSKQFD 221


>gi|4503559 epithelial membrane protein 1 [Homo sapiens]
          Length = 157

 Score = 33.1 bits (74), Expect = 0.34
 Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 6/97 (6%)

Query: 100 AVRASSIFPILSVILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISA 159
           A++    F ILS+I   +  L      F   + N    +G   +   L  ++G+ +Y S 
Sbjct: 60  ALKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYTSH 119

Query: 160 NAGDPSKSDSKKNSYSYGWSFYFGALSFIIAEMVGVL 196
            A      +     Y +G+S+  G + F  + ++GVL
Sbjct: 120 YA------NRDGTQYHHGYSYILGWICFCFSFIIGVL 150


>gi|5031949 natural killer cell group 7 sequence [Homo sapiens]
          Length = 165

 Score = 33.1 bits (74), Expect = 0.34
 Identities = 41/187 (21%), Positives = 69/187 (36%), Gaps = 42/187 (22%)

Query: 12  LTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTHSGLWRTCCLEG 71
           L  +G         IA+ TD+W  + G   +                 HSGLW T     
Sbjct: 7   LALLGGSLGLMFCLIALSTDFWFEAVGPTHS----------------AHSGLWPT----- 45

Query: 72  NFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGLCIAASEFYKTR 131
                     H    + Y   T  + + AV    ++ ++SV  L +   C  +   +   
Sbjct: 46  ---------GHGDIISGYIHVTQTFSIMAV----LWALVSVSFLVLS--CFPS--LFPPG 88

Query: 132 HNIILSAGIFFVSAGLSNIIGIIVYISANAGDPSKSDSKKNSYSYGWSFYFGALSFIIAE 191
           H  ++S    F +A +S ++ + VY S     P     +     + WSFY G +S I+  
Sbjct: 89  HGPLVSTTAAFAAA-ISMVVAMAVYTSERWDQPPHPQIQT---FFSWSFYLGWVSAILLL 144

Query: 192 MVGVLAV 198
             G L++
Sbjct: 145 CTGALSL 151


>gi|4505907 peripheral myelin protein 22 [Homo sapiens]
          Length = 160

 Score = 32.7 bits (73), Expect = 0.45
 Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 16/106 (15%)

Query: 97  FLRAVRA----SSIFPILSVILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIG 152
           +L++V+A    S IF ILS+ L F          F  T+       GIF + AGL  +  
Sbjct: 61  WLQSVQATMILSIIFSILSLFLFF-------CQLFTLTKGGRFYITGIFQILAGLCVMSA 113

Query: 153 IIVYISANAGDPSKSDSKKNSYSYGWSFYFGALSFIIAEMVGVLAV 198
             +Y   +      SD     YSYG+++    ++F +A + GV+ V
Sbjct: 114 AAIYTVRHPEWHLNSD-----YSYGFAYILAWVAFPLALLSGVIYV 154


>gi|24430165 peripheral myelin protein 22 [Homo sapiens]
          Length = 160

 Score = 32.7 bits (73), Expect = 0.45
 Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 16/106 (15%)

Query: 97  FLRAVRA----SSIFPILSVILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIG 152
           +L++V+A    S IF ILS+ L F          F  T+       GIF + AGL  +  
Sbjct: 61  WLQSVQATMILSIIFSILSLFLFF-------CQLFTLTKGGRFYITGIFQILAGLCVMSA 113

Query: 153 IIVYISANAGDPSKSDSKKNSYSYGWSFYFGALSFIIAEMVGVLAV 198
             +Y   +      SD     YSYG+++    ++F +A + GV+ V
Sbjct: 114 AAIYTVRHPEWHLNSD-----YSYGFAYILAWVAFPLALLSGVIYV 154


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.132    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,914,731
Number of Sequences: 37866
Number of extensions: 444488
Number of successful extensions: 1470
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 49
Number of HSP's that attempted gapping in prelim test: 1401
Number of HSP's gapped (non-prelim): 72
length of query: 323
length of database: 18,247,518
effective HSP length: 102
effective length of query: 221
effective length of database: 14,385,186
effective search space: 3179126106
effective search space used: 3179126106
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.