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Search of human proteins with 51599156
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
sapiens]
(1912 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa... 3903 0.0
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 2719 0.0
gi|158420731 chromodomain helicase DNA binding protein 3 isoform... 2629 0.0
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ... 2625 0.0
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ... 2621 0.0
gi|118421089 chromodomain helicase DNA binding protein 2 isoform... 591 e-168
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa... 569 e-161
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 531 e-150
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa... 520 e-147
gi|29244924 chromodomain helicase DNA binding protein 6 [Homo sa... 519 e-146
gi|114326455 chromodomain helicase DNA binding protein 8 [Homo s... 512 e-144
gi|164419749 SWI/SNF-related matrix-associated actin-dependent r... 428 e-119
gi|21071044 SWI/SNF-related matrix-associated actin-dependent re... 419 e-116
gi|21071058 SWI/SNF-related matrix-associated actin-dependent re... 415 e-115
gi|148612870 chromodomain helicase DNA binding protein 1-like [H... 408 e-113
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r... 394 e-109
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r... 394 e-109
gi|192807318 SWI/SNF-related matrix-associated actin-dependent r... 392 e-108
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 392 e-108
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 392 e-108
gi|192807314 SWI/SNF-related matrix-associated actin-dependent r... 391 e-108
gi|192807312 SWI/SNF-related matrix-associated actin-dependent r... 390 e-108
gi|21071056 SWI/SNF-related matrix-associated actin-dependent re... 390 e-108
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r... 386 e-106
gi|190358536 SWI/SNF-related, matrix-associated actin-dependent ... 274 5e-73
gi|190358532 SWI/SNF-related, matrix-associated actin-dependent ... 274 5e-73
gi|190358534 SWI/SNF-related, matrix-associated actin-dependent ... 271 4e-72
gi|21914927 helicase, lymphoid-specific [Homo sapiens] 269 2e-71
gi|4557565 excision repair cross-complementing rodent repair def... 253 1e-66
gi|216548193 RAD54-like protein [Homo sapiens] 221 4e-57
>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
sapiens]
Length = 1912
Score = 3903 bits (10122), Expect = 0.0
Identities = 1912/1912 (100%), Positives = 1912/1912 (100%)
Query: 1 MASGLGSPSPCSAGSEEEDMDALLNNSLPPPHPENEEDPEEDLSETETPKLKKKKKPKKP 60
MASGLGSPSPCSAGSEEEDMDALLNNSLPPPHPENEEDPEEDLSETETPKLKKKKKPKKP
Sbjct: 1 MASGLGSPSPCSAGSEEEDMDALLNNSLPPPHPENEEDPEEDLSETETPKLKKKKKPKKP 60
Query: 61 RDPKIPKSKRQKKERMLLCRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKL 120
RDPKIPKSKRQKKERMLLCRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKL
Sbjct: 61 RDPKIPKSKRQKKERMLLCRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKL 120
Query: 121 GPKKEKKSKSKRKEEEEEEDDDDDSKEPKSSAQLLEDWGMEDIDHVFSEEDYRTLTNYKA 180
GPKKEKKSKSKRKEEEEEEDDDDDSKEPKSSAQLLEDWGMEDIDHVFSEEDYRTLTNYKA
Sbjct: 121 GPKKEKKSKSKRKEEEEEEDDDDDSKEPKSSAQLLEDWGMEDIDHVFSEEDYRTLTNYKA 180
Query: 181 FSQFVRPLIAAKNPKIAVSKMMMVLGAKWREFSTNNPFKGSSGASVAAAAAAAVAVVESM 240
FSQFVRPLIAAKNPKIAVSKMMMVLGAKWREFSTNNPFKGSSGASVAAAAAAAVAVVESM
Sbjct: 181 FSQFVRPLIAAKNPKIAVSKMMMVLGAKWREFSTNNPFKGSSGASVAAAAAAAVAVVESM 240
Query: 241 VTATEVAPPPPPVEVPIRKAKTKEGKGPNARRKPKGSPRVPDAKKPKPKKVAPLKIKLGG 300
VTATEVAPPPPPVEVPIRKAKTKEGKGPNARRKPKGSPRVPDAKKPKPKKVAPLKIKLGG
Sbjct: 241 VTATEVAPPPPPVEVPIRKAKTKEGKGPNARRKPKGSPRVPDAKKPKPKKVAPLKIKLGG 300
Query: 301 FGSKRKRSSSEDDDLDVESDFDDASINSYSVSDGSTSRSSRSRKKLRTTKKKKKGEEEVT 360
FGSKRKRSSSEDDDLDVESDFDDASINSYSVSDGSTSRSSRSRKKLRTTKKKKKGEEEVT
Sbjct: 301 FGSKRKRSSSEDDDLDVESDFDDASINSYSVSDGSTSRSSRSRKKLRTTKKKKKGEEEVT 360
Query: 361 AVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHMVCLDPDMEKAPEGKWSCPHCEKEGIQ 420
AVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHMVCLDPDMEKAPEGKWSCPHCEKEGIQ
Sbjct: 361 AVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHMVCLDPDMEKAPEGKWSCPHCEKEGIQ 420
Query: 421 WEAKEDNSEGEEILEEVGGDLEEEDDHHMEFCRVCKDGGELLCCDTCPSSYHIHCLNPPL 480
WEAKEDNSEGEEILEEVGGDLEEEDDHHMEFCRVCKDGGELLCCDTCPSSYHIHCLNPPL
Sbjct: 421 WEAKEDNSEGEEILEEVGGDLEEEDDHHMEFCRVCKDGGELLCCDTCPSSYHIHCLNPPL 480
Query: 481 PEIPNGEWLCPRCTCPALKGKVQKILIWKWGQPPSPTPVPRPPDADPNTPSPKPLEGRPE 540
PEIPNGEWLCPRCTCPALKGKVQKILIWKWGQPPSPTPVPRPPDADPNTPSPKPLEGRPE
Sbjct: 481 PEIPNGEWLCPRCTCPALKGKVQKILIWKWGQPPSPTPVPRPPDADPNTPSPKPLEGRPE 540
Query: 541 RQFFVKWQGMSYWHCSWVSELQLELHCQVMFRNYQRKNDMDEPPSGDFGGDEEKSRKRKN 600
RQFFVKWQGMSYWHCSWVSELQLELHCQVMFRNYQRKNDMDEPPSGDFGGDEEKSRKRKN
Sbjct: 541 RQFFVKWQGMSYWHCSWVSELQLELHCQVMFRNYQRKNDMDEPPSGDFGGDEEKSRKRKN 600
Query: 601 KDPKFAEMEERFYRYGIKPEWMMIHRILNHSVDKKGHVHYLIKWRDLPYDQASWESEDVE 660
KDPKFAEMEERFYRYGIKPEWMMIHRILNHSVDKKGHVHYLIKWRDLPYDQASWESEDVE
Sbjct: 601 KDPKFAEMEERFYRYGIKPEWMMIHRILNHSVDKKGHVHYLIKWRDLPYDQASWESEDVE 660
Query: 661 IQDYDLFKQSYWNHRELMRGEEGRPGKKLKKVKLRKLERPPETPTVDPTVKYERQPEYLD 720
IQDYDLFKQSYWNHRELMRGEEGRPGKKLKKVKLRKLERPPETPTVDPTVKYERQPEYLD
Sbjct: 661 IQDYDLFKQSYWNHRELMRGEEGRPGKKLKKVKLRKLERPPETPTVDPTVKYERQPEYLD 720
Query: 721 ATGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLV 780
ATGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLV
Sbjct: 721 ATGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLV 780
Query: 781 SAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASRMKKE 840
SAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASRMKKE
Sbjct: 781 SAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASRMKKE 840
Query: 841 ASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNGYSLQHKLLL 900
ASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNGYSLQHKLLL
Sbjct: 841 ASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNGYSLQHKLLL 900
Query: 901 TGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFADIAKEDQIKKLHDMLGPHMLRRLKA 960
TGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFADIAKEDQIKKLHDMLGPHMLRRLKA
Sbjct: 901 TGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFADIAKEDQIKKLHDMLGPHMLRRLKA 960
Query: 961 DVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGGNQVSLLNVVMDLKKCCN 1020
DVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGGNQVSLLNVVMDLKKCCN
Sbjct: 961 DVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGGNQVSLLNVVMDLKKCCN 1020
Query: 1021 HPYLFPVAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKNLKEGGHRVLIFSQMTKMLD 1080
HPYLFPVAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKNLKEGGHRVLIFSQMTKMLD
Sbjct: 1021 HPYLFPVAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKNLKEGGHRVLIFSQMTKMLD 1080
Query: 1081 LLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADT 1140
LLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADT
Sbjct: 1081 LLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADT 1140
Query: 1141 VIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKKKMMLTHLVVR 1200
VIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKKKMMLTHLVVR
Sbjct: 1141 VIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKKKMMLTHLVVR 1200
Query: 1201 PGLGSKTGSMSKQELDDILKFGTEELFKDEATDGGGDNKEGEDSSVIHYDDKAIERLLDR 1260
PGLGSKTGSMSKQELDDILKFGTEELFKDEATDGGGDNKEGEDSSVIHYDDKAIERLLDR
Sbjct: 1201 PGLGSKTGSMSKQELDDILKFGTEELFKDEATDGGGDNKEGEDSSVIHYDDKAIERLLDR 1260
Query: 1261 NQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEEEVEREIIKQEESVDPDYWEKLLRH 1320
NQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEEEVEREIIKQEESVDPDYWEKLLRH
Sbjct: 1261 NQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEEEVEREIIKQEESVDPDYWEKLLRH 1320
Query: 1321 HYEQQQEDLARNLGKGKRIRKQVNYNDGSQEDRDWQDDQSDNQSDYSVASEEGDEDFDER 1380
HYEQQQEDLARNLGKGKRIRKQVNYNDGSQEDRDWQDDQSDNQSDYSVASEEGDEDFDER
Sbjct: 1321 HYEQQQEDLARNLGKGKRIRKQVNYNDGSQEDRDWQDDQSDNQSDYSVASEEGDEDFDER 1380
Query: 1381 SEAPRRPSRKGLRNDKDKPLPPLLARVGGNIEVLGFNARQRKAFLNAIMRYGMPPQDAFT 1440
SEAPRRPSRKGLRNDKDKPLPPLLARVGGNIEVLGFNARQRKAFLNAIMRYGMPPQDAFT
Sbjct: 1381 SEAPRRPSRKGLRNDKDKPLPPLLARVGGNIEVLGFNARQRKAFLNAIMRYGMPPQDAFT 1440
Query: 1441 TQWLVRDLRGKSEKEFKAYVSLFMRHLCEPGADGAETFADGVPREGLSRQHVLTRIGVMS 1500
TQWLVRDLRGKSEKEFKAYVSLFMRHLCEPGADGAETFADGVPREGLSRQHVLTRIGVMS
Sbjct: 1441 TQWLVRDLRGKSEKEFKAYVSLFMRHLCEPGADGAETFADGVPREGLSRQHVLTRIGVMS 1500
Query: 1501 LIRKKVQEFEHVNGRWSMPELAEVEENKKMSQPGSPSPKTPTPSTPGDTQPNTPAPVPPA 1560
LIRKKVQEFEHVNGRWSMPELAEVEENKKMSQPGSPSPKTPTPSTPGDTQPNTPAPVPPA
Sbjct: 1501 LIRKKVQEFEHVNGRWSMPELAEVEENKKMSQPGSPSPKTPTPSTPGDTQPNTPAPVPPA 1560
Query: 1561 EDGIKIEENSLKEEESIEGEKEVKSTAPETAIECTQAPAPASEDEKVVVEPPEGEEKVEK 1620
EDGIKIEENSLKEEESIEGEKEVKSTAPETAIECTQAPAPASEDEKVVVEPPEGEEKVEK
Sbjct: 1561 EDGIKIEENSLKEEESIEGEKEVKSTAPETAIECTQAPAPASEDEKVVVEPPEGEEKVEK 1620
Query: 1621 AEVKERTEEPMETEPKGAADVEKVEEKSAIDLTPIVVEDKEEKKEEEEKKEVMLQNGETP 1680
AEVKERTEEPMETEPKGAADVEKVEEKSAIDLTPIVVEDKEEKKEEEEKKEVMLQNGETP
Sbjct: 1621 AEVKERTEEPMETEPKGAADVEKVEEKSAIDLTPIVVEDKEEKKEEEEKKEVMLQNGETP 1680
Query: 1681 KDLNDEKQKKNIKQRFMFNIADGGFTELHSLWQNEERAATVTKKTYEIWHRRHDYWLLAG 1740
KDLNDEKQKKNIKQRFMFNIADGGFTELHSLWQNEERAATVTKKTYEIWHRRHDYWLLAG
Sbjct: 1681 KDLNDEKQKKNIKQRFMFNIADGGFTELHSLWQNEERAATVTKKTYEIWHRRHDYWLLAG 1740
Query: 1741 IINHGYARWQDIQNDPRYAILNEPFKGEMNRGNFLEIKNKFLARRFKLLEQALVIEEQLR 1800
IINHGYARWQDIQNDPRYAILNEPFKGEMNRGNFLEIKNKFLARRFKLLEQALVIEEQLR
Sbjct: 1741 IINHGYARWQDIQNDPRYAILNEPFKGEMNRGNFLEIKNKFLARRFKLLEQALVIEEQLR 1800
Query: 1801 RAAYLNMSEDPSHPSMALNTRFAEVECLAESHQHLSKESMAGNKPANAVLHKVLKQLEEL 1860
RAAYLNMSEDPSHPSMALNTRFAEVECLAESHQHLSKESMAGNKPANAVLHKVLKQLEEL
Sbjct: 1801 RAAYLNMSEDPSHPSMALNTRFAEVECLAESHQHLSKESMAGNKPANAVLHKVLKQLEEL 1860
Query: 1861 LSDMKADVTRLPATIARIPPVAVRLQMSERNILSRLANRAPEPTPQQVAQQQ 1912
LSDMKADVTRLPATIARIPPVAVRLQMSERNILSRLANRAPEPTPQQVAQQQ
Sbjct: 1861 LSDMKADVTRLPATIARIPPVAVRLQMSERNILSRLANRAPEPTPQQVAQQQ 1912
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 2719 bits (7047), Expect = 0.0
Identities = 1373/1954 (70%), Positives = 1566/1954 (80%), Gaps = 106/1954 (5%)
Query: 17 EEDMDALLNNSLPPPHPENEEDPE-----EDLSETETPKLKKKKKPKKPRDPKIPKSKRQ 71
EE++ L + +EE+ +D E L KKKKPKK ++ K K KR+
Sbjct: 8 EEELPRLFAEEMENEDEMSEEEDGGLEAFDDFFPVEPVSLPKKKKPKKLKENKC-KGKRK 66
Query: 72 KKERMLLCRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKLGPKKEKKSKSK 131
KKE G E E EE++ +S+SEGSDY+P KKKKKKL KKEKK+K K
Sbjct: 67 KKE------------GSNDELSENEEDLEEKSESEGSDYSPNKKKKKKLKDKKEKKAKRK 114
Query: 132 RKEEEEEEDDDDDSKEPKSSAQLLEDWGMEDIDHVFSEEDYRTLTNYKAFSQFVRPLIAA 191
+K+E+E+++DD KEPKSS QL+ +WG++D+D++FSEEDY TLTNYKAFSQF+RPLIA
Sbjct: 115 KKDEDEDDNDDGCLKEPKSSGQLMAEWGLDDVDYLFSEEDYHTLTNYKAFSQFLRPLIAK 174
Query: 192 KNPKIAVSKMMMVLGAKWREFSTNNPFKGSSGASVAAAAAAAVAVVESMVTATEVAPPPP 251
KNPKI +SKMM VLGAKWREFS NNPFKGSS A+ AAA AAAV V ++ V+PP
Sbjct: 175 KNPKIPMSKMMTVLGAKWREFSANNPFKGSSAAAAAAAVAAAVETV-TISPPLAVSPPQV 233
Query: 252 PVEVPIRKAKTKEGKGPNARRKPKGSPRVPDAKKPKPKKVAPLKIKLGGFGSKRKRSSSE 311
P VPIRKAKTKEGKGP R+K KGS KK K KK A LK + GG +KRK+ SS
Sbjct: 234 PQPVPIRKAKTKEGKGPGVRKKIKGSK--DGKKKGKGKKTAGLKFRFGGISNKRKKGSSS 291
Query: 312 DDDLDVESDFDDASINSYSVSDGSTSRSSRSRKKLRTTKKKKKGEEEVTAVDGYETDHQD 371
++D ESDFD ASI+S SV ++ + K+ R K+ G DGYETDHQD
Sbjct: 292 EEDEREESDFDSASIHSASVRSECSAALGKKSKRRRKKKRIDDG-------DGYETDHQD 344
Query: 372 YCEVCQQGGEIILCDTCPRAYHMVCLDPDMEKAPEGKWSCPHCEKEGIQWEAKEDNSEGE 431
YCEVCQQGGEIILCDTCPRAYH+VCLDP++EKAPEGKWSCPHCEKEGIQWE K+D+ E E
Sbjct: 345 YCEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHCEKEGIQWEPKDDDDEEE 404
Query: 432 EILEEVGGDLEEEDDHHMEFCRVCKDGGELLCCDTCPSSYHIHCLNPPLPEIPNGEWLCP 491
E G EEE+D HMEFCRVCKDGGELLCCD CPSSYH+HCLNPPLPEIPNGEWLCP
Sbjct: 405 E------GGCEEEEDDHMEFCRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGEWLCP 458
Query: 492 RCTCPALKGKVQKILIWKWGQPPSPTPVPRP-PDADPNTPSPKPLEGRPERQFFVKWQGM 550
RCTCP LKGKVQ+IL W+W +PP+P V P PD +P+ P PKPLEG PER+FFVKW G+
Sbjct: 459 RCTCPPLKGKVQRILHWRWTEPPAPFMVGLPGPDVEPSLPPPKPLEGIPEREFFVKWAGL 518
Query: 551 SYWHCSWVSELQLELHCQVMFRNYQRKNDMDEPPSGDFG-GDEE-KSRKRKNKDPKFAEM 608
SYWHCSWV ELQLEL+ VM+RNYQRKNDMDEPP D+G GDE+ KS KRKNKDP +A+M
Sbjct: 519 SYWHCSWVKELQLELYHTVMYRNYQRKNDMDEPPPFDYGSGDEDGKSEKRKNKDPLYAKM 578
Query: 609 EERFYRYGIKPEWMMIHRILNHSVDKKGHVHYLIKWRDLPYDQASWESEDVEIQDYDLFK 668
EERFYRYGIKPEWMMIHRILNHS DKKG VHYLIKW+DLPYDQ +WE +D++I YD K
Sbjct: 579 EERFYRYGIKPEWMMIHRILNHSFDKKGDVHYLIKWKDLPYDQCTWEIDDIDIPYYDNLK 638
Query: 669 QSYWNHRELMRGEEGRPGKKL----KKVKLRKLERPPETPTVDPTVKYERQPEYLDATGG 724
Q+YW HRELM GE+ R K+L KK++ K E+PP+TP VDPTVK+++QP Y+D+TGG
Sbjct: 639 QAYWGHRELMLGEDTRLPKRLLKKGKKLRDDKQEKPPDTPIVDPTVKFDKQPWYIDSTGG 698
Query: 725 TLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLVSAPL 784
TLHPYQ+EGLNWLRFSWAQGTDTILADEMGLGKTVQT VFLYSLYKEGHSKGP+LVSAPL
Sbjct: 699 TLHPYQLEGLNWLRFSWAQGTDTILADEMGLGKTVQTIVFLYSLYKEGHSKGPYLVSAPL 758
Query: 785 STIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASRMKKEASVK 844
STIINWEREFEMWAPD YVVTY GDK+SR++IRENEFSFEDNAIR GKK RMKKE +K
Sbjct: 759 STIINWEREFEMWAPDFYVVTYTGDKESRSVIRENEFSFEDNAIRSGKKVFRMKKEVQIK 818
Query: 845 FHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNGYSLQHKLLLTGTP 904
FHVLLTSYELITID AILGSI+WACL+VDEAHRLKNNQSKFFRVLN Y + +KLLLTGTP
Sbjct: 819 FHVLLTSYELITIDQAILGSIEWACLVVDEAHRLKNNQSKFFRVLNSYKIDYKLLLTGTP 878
Query: 905 LQNNLEELFHLLNFLTPERFHNLEGFLEEFADIAKEDQIKKLHDMLGPHMLRRLKADVFK 964
LQNNLEELFHLLNFLTPERF+NLEGFLEEFADI+KEDQIKKLHD+LGPHMLRRLKADVFK
Sbjct: 879 LQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLRRLKADVFK 938
Query: 965 NMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGGNQVSLLNVVMDLKKCCNHPYL 1024
NMP+KTELIVRVELS MQKKYYK+ILTRNFEALN++GGGNQVSLLN++MDLKKCCNHPYL
Sbjct: 939 NMPAKTELIVRVELSQMQKKYYKFILTRNFEALNSKGGGNQVSLLNIMMDLKKCCNHPYL 998
Query: 1025 FPVAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKNLKEGGHRVLIFSQMTKMLDLLED 1084
FPVAA+EAP +PNG YDGS+L+++SGKL+LLQKMLK L++ GHRVLIFSQMTKMLDLLED
Sbjct: 999 FPVAAVEAPVLPNGSYDGSSLVKSSGKLMLLQKMLKKLRDEGHRVLIFSQMTKMLDLLED 1058
Query: 1085 FLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIY 1144
FLE+EGYKYERIDGGITG +RQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIY
Sbjct: 1059 FLEYEGYKYERIDGGITGGLRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIY 1118
Query: 1145 DSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKKKMMLTHLVVRPGLG 1204
DSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAK+KMMLTHLVVRPGLG
Sbjct: 1119 DSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKRKMMLTHLVVRPGLG 1178
Query: 1205 SKTGSMSKQELDDILKFGTEELFKD-------------------EATDGG---------- 1235
SK+GSM+KQELDDILKFGTEELFKD +++ GG
Sbjct: 1179 SKSGSMTKQELDDILKFGTEELFKDDVEGMMSQGQRPVTPIPDVQSSKGGNLAASAKKKH 1238
Query: 1236 -----GDNKEGEDSSVIHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVVREE 1290
GDNK+ EDSSVIHYDD AI +LLDRNQD T+DTELQ MNEYLSSFKVAQYVVREE
Sbjct: 1239 GSTPPGDNKDVEDSSVIHYDDAAISKLLDRNQDATDDTELQNMNEYLSSFKVAQYVVREE 1298
Query: 1291 EMGEEEEVEREIIKQEESVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYNDGSQ 1350
+ EEVEREIIKQEE+VDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYND SQ
Sbjct: 1299 D--GVEEVEREIIKQEENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYNDASQ 1356
Query: 1351 EDRDWQDDQSDNQSDYSVASEEGDEDFDERSE--APRRPSRKGLRNDKDKPLPPLLARVG 1408
ED++WQD+ SDNQS+YS+ SE+ DEDF+ER E + RR SR+ L++D+DKPLPPLLARVG
Sbjct: 1357 EDQEWQDELSDNQSEYSIGSEDEDEDFEERPEGQSGRRQSRRQLKSDRDKPLPPLLARVG 1416
Query: 1409 GNIEVLGFNARQRKAFLNAIMRYGMPPQDAFTTQWLVRDLRGKSEKEFKAYVSLFMRHLC 1468
GNIEVLGFNARQRKAFLNAIMR+GMPPQDAF + WLVRDLRGKSEKEF+AYVSLFMRHLC
Sbjct: 1417 GNIEVLGFNARQRKAFLNAIMRWGMPPQDAFNSHWLVRDLRGKSEKEFRAYVSLFMRHLC 1476
Query: 1469 EPGADGAETFADGVPREGLSRQHVLTRIGVMSLIRKKVQEFEHVNGRWSMPEL-AEVEEN 1527
EPGADGAETFADGVPREGLSRQHVLTRIGVMSL+RKKVQEFEHVNG++S P+L E E
Sbjct: 1477 EPGADGAETFADGVPREGLSRQHVLTRIGVMSLVRKKVQEFEHVNGKYSTPDLIPEGPEG 1536
Query: 1528 KKMSQPGSPSPKTPTPSTPGDTQPNTPAPVPPAEDGIKIEENSLKEEESIEGEKEVKSTA 1587
KK + S P TP P++P P P +P + ++ + EK+ +
Sbjct: 1537 KKSGEVISSDPNTPVPASPAHLLP-APLGLP----------DKMEAQLGYMDEKDPGAQK 1585
Query: 1588 PETAIECTQAPAP----ASEDEKVVVEPPEGEEKVEKAEVKERTEEPMETEPKGAADV-- 1641
P +E PA SED+ E P +E+ + +E + P E +V
Sbjct: 1586 PRQPLEVQALPAALDRVESEDKH---ESPASKERAREERPEETEKAPPSPEQLPREEVLP 1642
Query: 1642 --EKVEEKSAIDLTPIVVEDKE----EKKEEEEKKEVMLQNGETPKDLNDEKQKKNIKQR 1695
EK+ +K + L + E + K EE++ QNG+ +D +K+ K K +
Sbjct: 1643 EKEKILDKLELSLIHSRGDSSELRPDDTKAEEKEPIETQQNGDKEEDDEGKKEDKKGKFK 1702
Query: 1696 FMFNIADGGFTELHSLWQNEERAATVTKKTYEIWHRRHDYWLLAGIINHGYARWQDIQND 1755
FMFNIADGGFTELH+LWQNEERAA + K Y+IWHRRHDYWLLAGI+ HGYARWQDIQND
Sbjct: 1703 FMFNIADGGFTELHTLWQNEERAAVSSGKIYDIWHRRHDYWLLAGIVTHGYARWQDIQND 1762
Query: 1756 PRYAILNEPFKGEMNRGNFLEIKNKFLARRFKLLEQALVIEEQLRRAAYLNMSEDPSHPS 1815
PRY ILNEPFK E+++GN+LE+KNKFLARRFKLLEQALVIEEQLRRAAYLNM++DP+HP+
Sbjct: 1763 PRYMILNEPFKSEVHKGNYLEMKNKFLARRFKLLEQALVIEEQLRRAAYLNMTQDPNHPA 1822
Query: 1816 MALNTRFAEVECLAESHQHLSKESMAGNKPANAVLHKVLKQLEELLSDMKADVTRLPATI 1875
MALN R AEVECLAESHQHLSKES+AGNKPANAVLHKVL QLEELLSDMKADVTRLP+ +
Sbjct: 1823 MALNARLAEVECLAESHQHLSKESLAGNKPANAVLHKVLNQLEELLSDMKADVTRLPSML 1882
Query: 1876 ARIPPVAVRLQMSERNILSRLANRAPEPTPQQVA 1909
+RIPPVA RLQMSER+ILSRL NRA +PT QQ A
Sbjct: 1883 SRIPPVAARLQMSERSILSRLTNRAGDPTIQQGA 1916
>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
[Homo sapiens]
Length = 2059
Score = 2629 bits (6814), Expect = 0.0
Identities = 1351/1945 (69%), Positives = 1539/1945 (79%), Gaps = 119/1945 (6%)
Query: 28 LPPPHPENEEDPEEDLSETETPKLKKKKK-PKKPRDPKIPKSKRQKKERMLLCRQLGDSS 86
LPPP P D ++ +KK+K+ PKK ++ K K +++KK DS
Sbjct: 83 LPPPPPPPPPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKR---------DSE 133
Query: 87 GEGPEFVEEEEEVALRSDSEGSDYT--PGKKKKKKLGPKKEKKSKSKRKEEEEEEDDDDD 144
EF E +E +S+S GS+Y PG+K+++K KKEKK+K ++K E D
Sbjct: 134 ---EEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKGEG---DGGQK 187
Query: 145 SKEPKSSAQLLEDWGMEDIDHVFSEEDYRTLTNYKAFSQFVRPLIAAKNPKIAVSKMMMV 204
E KSSA LL WG+ED++HVFSEEDY TLTNYKAFSQF+RPLIA KNPKI +SKMM +
Sbjct: 188 QVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPMSKMMTI 247
Query: 205 LGAKWREFSTNNPFKGSSGASVAAAAAAAVAVVESMVTATEVA-----------PPPPPV 253
LGAKWREFS NNPFKGS+ A AAAAAAA AV E + A A PPPP
Sbjct: 248 LGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPALPPPPAA 307
Query: 254 EV---PIRKAKTKEGKGPNARRKPKGSPRVPDA-KKPKPKKVAPLKIKLGGFGSKRKRSS 309
++ PIR+AKTKEGKGP +R+ K SPRVPD KK + KK+APLKIKLG G KRK+
Sbjct: 308 DIQPPPIRRAKTKEGKGPGHKRRSK-SPRVPDGRKKLRGKKMAPLKIKLGLLGGKRKKGG 366
Query: 310 SEDDDLDV-------ESDFDDASINSYSVSDGSTSRSSRSRKKLRTTKKKK-------KG 355
S D ESD D S++S S R+ + ++ KKKK G
Sbjct: 367 SYVFQSDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVLGCPAVAG 426
Query: 356 EEEVTAVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHMVCLDPDMEKAPEGKWSCPHCE 415
EEEV DGYETDHQDYCEVCQQGGEIILCDTCPRAYH+VCLDP++++APEGKWSCPHCE
Sbjct: 427 EEEV---DGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCE 483
Query: 416 KEGIQWEAKEDNSEGEEILEEVGGDLEEEDDHHMEFCRVCKDGGELLCCDTCPSSYHIHC 475
KEG+QWEAKE+ E EE EE G +EE+D HME+CRVCKDGGELLCCD C SSYHIHC
Sbjct: 484 KEGVQWEAKEEEEEYEEEGEEEGE--KEEEDDHMEYCRVCKDGGELLCCDACISSYHIHC 541
Query: 476 LNPPLPEIPNGEWLCPRCTCPALKGKVQKILIWKWGQPPSPTPVPRPPDADPNTPSPKPL 535
LNPPLP+IPNGEWLCPRCTCP LKG+VQKIL W+WG+PP P P+ D +P+ P P+PL
Sbjct: 542 LNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPRPL 601
Query: 536 EGRPERQFFVKWQGMSYWHCSWVSELQLELHCQVMFRNYQRKNDMDEPPSGDFGGDEE-- 593
+GR ER+FFVKW G+SYWHCSW ELQLE+ VM+RNYQRKNDMDEPP D+G E+
Sbjct: 602 QGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGEDDG 661
Query: 594 KSRKRKNKDPKFAEMEERFYRYGIKPEWMMIHRILNHSVDKKGHVHYLIKWRDLPYDQAS 653
KS KRK KDP +AEMEE++YR+GIKPEWM +HRI+NHSVDKKG+ HYL+KWRDLPYDQ++
Sbjct: 662 KSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQST 721
Query: 654 WESEDVEIQDYDLFKQSYWNHRELMRGEE-GRPGKKLKKVKLRKLERPPETPTVDPTVKY 712
WE +++ I +Y+ KQSYW HREL+ GE+ +P K KK K + + PP +PT DPTVKY
Sbjct: 722 WEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTVKY 781
Query: 713 ERQPEYLDATGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEG 772
E QP ++ ATGGTLH YQ+EGLNWLRFSWAQGTDTILADEMGLGKT+QT VFLYSLYKEG
Sbjct: 782 ETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYKEG 841
Query: 773 HSKGPFLVSAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGK 832
H+KGPFLVSAPLSTIINWEREF+MWAP YVVTY GDKDSRAIIRENEFSFEDNAI+GGK
Sbjct: 842 HTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGK 901
Query: 833 KASRMKKEASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNGY 892
KA +MK+EA VKFHVLLTSYELITID A LGSI WACL+VDEAHRLKNNQSKFFRVLNGY
Sbjct: 902 KAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGY 961
Query: 893 SLQHKLLLTGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFADIAKEDQIKKLHDMLGP 952
+ HKLLLTGTPLQNNLEELFHLLNFLTPERF+NLEGFLEEFADI+KEDQIKKLHD+LGP
Sbjct: 962 KIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGP 1021
Query: 953 HMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGGNQVSLLNVV 1012
HMLRRLKADVFKNMP+KTELIVRVELSPMQKKYYKYILTRNFEALN+RGGGNQVSLLN++
Sbjct: 1022 HMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIM 1081
Query: 1013 MDLKKCCNHPYLFPVAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKNLKEGGHRVLIF 1072
MDLKKCCNHPYLFPVAAME+PK+P+G Y+G ALI++SGKL+LLQKML+ LKE GHRVLIF
Sbjct: 1082 MDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLIF 1141
Query: 1073 SQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFCFLLSTRAGGLG 1132
SQMTKMLDLLEDFL++EGYKYERIDGGITG +RQEAIDRFNAPGAQQFCFLLSTRAGGLG
Sbjct: 1142 SQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGGLG 1201
Query: 1133 INLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKKKM 1192
INLATADTVII+DSDWNPHNDIQAFSRAHRIGQ KVMIYRFVTRASVEERITQVAK+KM
Sbjct: 1202 INLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKM 1261
Query: 1193 MLTHLVVRPGLGSKTGSMSKQELDDILKFGTEELFKDEATDGGGDNKEGEDSSVIHYDDK 1252
MLTHLVVRPGLGSK GSMSKQELDDILKFGTEELFKDE G+NKE EDSSVIHYD++
Sbjct: 1262 MLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDE---NEGENKE-EDSSVIHYDNE 1317
Query: 1253 AIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEEEVEREIIKQEESVDPD 1312
AI RLLDRNQD TEDT++Q MNEYLSSFKVAQYVVREE+ + EE+EREIIKQEE+VDPD
Sbjct: 1318 AIARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREED--KIEEIEREIIKQEENVDPD 1375
Query: 1313 YWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYNDGSQEDRDWQDDQSDNQSDYSVASEE 1372
YWEKLLRHHYEQQQEDLARNLGKGKR+RKQVNYND +QED+ DNQS+YSV SEE
Sbjct: 1376 YWEKLLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQ-------DNQSEYSVGSEE 1428
Query: 1373 GDEDFDERSEAPRRPSRKGLRNDKDKPLPPLLARVGGNIEVLGFNARQRKAFLNAIMRYG 1432
DEDFDER E RR S++ LRN+KDKPLPPLLARVGGNIEVLGFN RQRKAFLNA+MR+G
Sbjct: 1429 EDEDFDERPEG-RRQSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWG 1487
Query: 1433 MPPQDAFTTQWLVRDLRGKSEKEFKAYVSLFMRHLCEPGADGAETFADGVPREGLSRQHV 1492
MPPQDAFTTQWLVRDLRGK+EKEFKAYVSLFMRHLCEPGADG+ETFADGVPREGLSRQ V
Sbjct: 1488 MPPQDAFTTQWLVRDLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQV 1547
Query: 1493 LTRIGVMSLIRKKVQEFEHVNGRWSMPEL-----AEVEENKKMSQPGSPSPKTPTPSTPG 1547
LTRIGVMSL++KKVQEFEH+NGRWSMPEL A+ + + + S P SP TP S
Sbjct: 1548 LTRIGVMSLVKKKVQEFEHINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATN 1607
Query: 1548 DTQPNTPAPVPPAEDGIKIEENSLKEEESIEGEKEVKSTAPETAIECTQAPAPASEDEKV 1607
+ PA P+E G I KEE + EK K++ +E T+A AP+
Sbjct: 1608 SPCTSKPATPAPSEKGEGIRTPLEKEEAENQEEKPEKNSRIGEKME-TEADAPS------ 1660
Query: 1608 VVEPPEGEEKVEKAEVKERTEEP-----METEPKGAADVEKVEEKSAIDLTPIVVEDKEE 1662
P E++E ++ E P ME EP D EKSA + TP E EE
Sbjct: 1661 --PAPSLGERLEPRKIPLEDEVPGVPGEMEPEPGYRGD----REKSATESTP--GERGEE 1712
Query: 1663 K-------------------KEEEEKKEVMLQNGETPKD---LNDEKQKKNIKQRFMFNI 1700
K K E+ K + L+ G P+D N +++K K RFMFNI
Sbjct: 1713 KPLDGQEHRERPEGETGDLGKREDVKGDRELRPG--PRDEPRSNGRREEKTEKPRFMFNI 1770
Query: 1701 ADGGFTELHSLWQNEERAATVTKKTYEIWHRRHDYWLLAGIINHGYARWQDIQNDPRYAI 1760
ADGGFTELH+LWQNEERAA + K EIWHRRHDYWLLAGI+ HGYARWQDIQND ++AI
Sbjct: 1771 ADGGFTELHTLWQNEERAAISSGKLNEIWHRRHDYWLLAGIVLHGYARWQDIQNDAQFAI 1830
Query: 1761 LNEPFKGEMNRGNFLEIKNKFLARRFKLLEQALVIEEQLRRAAYLNMSEDPSHPSMALNT 1820
+NEPFK E N+GNFLE+KNKFLARRFKLLEQALVIEEQLRRAAYLN+S++P+HP+MAL+
Sbjct: 1831 INEPFKTEANKGNFLEMKNKFLARRFKLLEQALVIEEQLRRAAYLNLSQEPAHPAMALHA 1890
Query: 1821 RFAEVECLAESHQHLSKESMAGNKPANAVLHKVLKQLEELLSDMKADVTRLPATIARIPP 1880
RFAE ECLAESHQHLSKES+AGNKPANAVLHKVL QLEELLSDMKADVTRLPAT++RIPP
Sbjct: 1891 RFAEAECLAESHQHLSKESLAGNKPANAVLHKVLNQLEELLSDMKADVTRLPATLSRIPP 1950
Query: 1881 VAVRLQMSERNILSRLANRAPEPTP 1905
+A RLQMSER+ILSRLA++ EP P
Sbjct: 1951 IAARLQMSERSILSRLASKGTEPHP 1975
Score = 34.3 bits (77), Expect = 1.2
Identities = 37/145 (25%), Positives = 59/145 (40%), Gaps = 21/145 (14%)
Query: 1541 PTPSTPGDTQPNTPAPVPPAEDGIKIEENSLKEEESIEGEKEVKSTAPETAIECTQAPAP 1600
P P P P P P PP +D I++ ++L ++ G K+ K P +
Sbjct: 74 PPPPPPPPPLPPPPPPPPPDKDDIRLLPSALGVKKRKRGPKKQKENKPGK----PRKRKK 129
Query: 1601 ASEDEKVVVEPPEGEEKVE--------------KAEVKERTEEPMETEPKGAAD--VEKV 1644
+E+ E E EK E + + +E+ E+ + KG D ++V
Sbjct: 130 RDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKGEGDGGQKQV 189
Query: 1645 EEK-SAIDLTPIVVEDKEEKKEEEE 1668
E+K SA L +ED E EE+
Sbjct: 190 EQKSSATLLLTWGLEDVEHVFSEED 214
>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
[Homo sapiens]
Length = 2000
Score = 2625 bits (6803), Expect = 0.0
Identities = 1351/1951 (69%), Positives = 1540/1951 (78%), Gaps = 121/1951 (6%)
Query: 24 LNNSLPPPHPENEEDPEED---LSETETPKLKKKKKPKKPRDPKIPKSKRQKKERMLLCR 80
L S PP + P++D L + K+K+ PKK ++ K K +++KK
Sbjct: 18 LRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKR------ 71
Query: 81 QLGDSSGEGPEFVEEEEEVALRSDSEGSDYT--PGKKKKKKLGPKKEKKSKSKRKEEEEE 138
DS EF E +E +S+S GS+Y PG+K+++K KKEKK+K ++K E
Sbjct: 72 ---DSE---EEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKGEG-- 123
Query: 139 EDDDDDSKEPKSSAQLLEDWGMEDIDHVFSEEDYRTLTNYKAFSQFVRPLIAAKNPKIAV 198
D E KSSA LL WG+ED++HVFSEEDY TLTNYKAFSQF+RPLIA KNPKI +
Sbjct: 124 -DGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPM 182
Query: 199 SKMMMVLGAKWREFSTNNPFKGSSGASVAAAAAAAVAVVESMVTATEVA----------- 247
SKMM +LGAKWREFS NNPFKGS+ A AAAAAAA AV E + A A
Sbjct: 183 SKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPAL 242
Query: 248 PPPPPVEV---PIRKAKTKEGKGPNARRKPKGSPRVPDA-KKPKPKKVAPLKIKLGGFGS 303
PPPP ++ PIR+AKTKEGKGP +R+ K SPRVPD KK + KK+APLKIKLG G
Sbjct: 243 PPPPAADIQPPPIRRAKTKEGKGPGHKRRSK-SPRVPDGRKKLRGKKMAPLKIKLGLLGG 301
Query: 304 KRKRSSSEDDDLDV-------ESDFDDASINSYSVSDGSTSRSSRSRKKLRTTKKKK--- 353
KRK+ S D ESD D S++S S R+ + ++ KKKK
Sbjct: 302 KRKKGGSYVFQSDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVLG 361
Query: 354 ----KGEEEVTAVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHMVCLDPDMEKAPEGKW 409
GEEEV DGYETDHQDYCEVCQQGGEIILCDTCPRAYH+VCLDP++++APEGKW
Sbjct: 362 CPAVAGEEEV---DGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKW 418
Query: 410 SCPHCEKEGIQWEAKEDNSEGEEILEEVGGDLEEEDDHHMEFCRVCKDGGELLCCDTCPS 469
SCPHCEKEG+QWEAKE+ E EE EE G +EE+D HME+CRVCKDGGELLCCD C S
Sbjct: 419 SCPHCEKEGVQWEAKEEEEEYEEEGEEEGE--KEEEDDHMEYCRVCKDGGELLCCDACIS 476
Query: 470 SYHIHCLNPPLPEIPNGEWLCPRCTCPALKGKVQKILIWKWGQPPSPTPVPRPPDADPNT 529
SYHIHCLNPPLP+IPNGEWLCPRCTCP LKG+VQKIL W+WG+PP P P+ D +P+
Sbjct: 477 SYHIHCLNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDV 536
Query: 530 PSPKPLEGRPERQFFVKWQGMSYWHCSWVSELQLELHCQVMFRNYQRKNDMDEPPSGDFG 589
P P+PL+GR ER+FFVKW G+SYWHCSW ELQLE+ VM+RNYQRKNDMDEPP D+G
Sbjct: 537 PPPRPLQGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYG 596
Query: 590 GDEE--KSRKRKNKDPKFAEMEERFYRYGIKPEWMMIHRILNHSVDKKGHVHYLIKWRDL 647
E+ KS KRK KDP +AEMEE++YR+GIKPEWM +HRI+NHSVDKKG+ HYL+KWRDL
Sbjct: 597 SGEDDGKSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDL 656
Query: 648 PYDQASWESEDVEIQDYDLFKQSYWNHRELMRGEE-GRPGKKLKKVKLRKLERPPETPTV 706
PYDQ++WE +++ I +Y+ KQSYW HREL+ GE+ +P K KK K + + PP +PT
Sbjct: 657 PYDQSTWEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTN 716
Query: 707 DPTVKYERQPEYLDATGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLY 766
DPTVKYE QP ++ ATGGTLH YQ+EGLNWLRFSWAQGTDTILADEMGLGKT+QT VFLY
Sbjct: 717 DPTVKYETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLY 776
Query: 767 SLYKEGHSKGPFLVSAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDN 826
SLYKEGH+KGPFLVSAPLSTIINWEREF+MWAP YVVTY GDKDSRAIIRENEFSFEDN
Sbjct: 777 SLYKEGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDN 836
Query: 827 AIRGGKKASRMKKEASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFF 886
AI+GGKKA +MK+EA VKFHVLLTSYELITID A LGSI WACL+VDEAHRLKNNQSKFF
Sbjct: 837 AIKGGKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFF 896
Query: 887 RVLNGYSLQHKLLLTGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFADIAKEDQIKKL 946
RVLNGY + HKLLLTGTPLQNNLEELFHLLNFLTPERF+NLEGFLEEFADI+KEDQIKKL
Sbjct: 897 RVLNGYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKL 956
Query: 947 HDMLGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGGNQV 1006
HD+LGPHMLRRLKADVFKNMP+KTELIVRVELSPMQKKYYKYILTRNFEALN+RGGGNQV
Sbjct: 957 HDLLGPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQV 1016
Query: 1007 SLLNVVMDLKKCCNHPYLFPVAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKNLKEGG 1066
SLLN++MDLKKCCNHPYLFPVAAME+PK+P+G Y+G ALI++SGKL+LLQKML+ LKE G
Sbjct: 1017 SLLNIMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQG 1076
Query: 1067 HRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFCFLLST 1126
HRVLIFSQMTKMLDLLEDFL++EGYKYERIDGGITG +RQEAIDRFNAPGAQQFCFLLST
Sbjct: 1077 HRVLIFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLST 1136
Query: 1127 RAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQ 1186
RAGGLGINLATADTVII+DSDWNPHNDIQAFSRAHRIGQ KVMIYRFVTRASVEERITQ
Sbjct: 1137 RAGGLGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQ 1196
Query: 1187 VAKKKMMLTHLVVRPGLGSKTGSMSKQELDDILKFGTEELFKDEATDGGGDNKEGEDSSV 1246
VAK+KMMLTHLVVRPGLGSK GSMSKQELDDILKFGTEELFKDE G+NKE EDSSV
Sbjct: 1197 VAKRKMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDE---NEGENKE-EDSSV 1252
Query: 1247 IHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEEEVEREIIKQE 1306
IHYD++AI RLLDRNQD TEDT++Q MNEYLSSFKVAQYVVREE+ + EE+EREIIKQE
Sbjct: 1253 IHYDNEAIARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREED--KIEEIEREIIKQE 1310
Query: 1307 ESVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYNDGSQEDRDWQDDQSDNQSDY 1366
E+VDPDYWEKLLRHHYEQQQEDLARNLGKGKR+RKQVNYND +QED+ DNQS+Y
Sbjct: 1311 ENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQ-------DNQSEY 1363
Query: 1367 SVASEEGDEDFDERSEAPRRPSRKGLRNDKDKPLPPLLARVGGNIEVLGFNARQRKAFLN 1426
SV SEE DEDFDER E RR S++ LRN+KDKPLPPLLARVGGNIEVLGFN RQRKAFLN
Sbjct: 1364 SVGSEEEDEDFDERPEG-RRQSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLN 1422
Query: 1427 AIMRYGMPPQDAFTTQWLVRDLRGKSEKEFKAYVSLFMRHLCEPGADGAETFADGVPREG 1486
A+MR+GMPPQDAFTTQWLVRDLRGK+EKEFKAYVSLFMRHLCEPGADG+ETFADGVPREG
Sbjct: 1423 AVMRWGMPPQDAFTTQWLVRDLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREG 1482
Query: 1487 LSRQHVLTRIGVMSLIRKKVQEFEHVNGRWSMPEL-----AEVEENKKMSQPGSPSPKTP 1541
LSRQ VLTRIGVMSL++KKVQEFEH+NGRWSMPEL A+ + + + S P SP TP
Sbjct: 1483 LSRQQVLTRIGVMSLVKKKVQEFEHINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTP 1542
Query: 1542 TPSTPGDTQPNTPAPVPPAEDGIKIEENSLKEEESIEGEKEVKSTAPETAIECTQAPAPA 1601
S + PA P+E G I KEE + EK K++ +E T+A AP+
Sbjct: 1543 EASATNSPCTSKPATPAPSEKGEGIRTPLEKEEAENQEEKPEKNSRIGEKME-TEADAPS 1601
Query: 1602 SEDEKVVVEPPEGEEKVEKAEVKERTEEP-----METEPKGAADVEKVEEKSAIDLTPIV 1656
P E++E ++ E P ME EP D EKSA + TP
Sbjct: 1602 --------PAPSLGERLEPRKIPLEDEVPGVPGEMEPEPGYRGD----REKSATESTP-- 1647
Query: 1657 VEDKEEK-------------------KEEEEKKEVMLQNGETPKD---LNDEKQKKNIKQ 1694
E EEK K E+ K + L+ G P+D N +++K K
Sbjct: 1648 GERGEEKPLDGQEHRERPEGETGDLGKREDVKGDRELRPG--PRDEPRSNGRREEKTEKP 1705
Query: 1695 RFMFNIADGGFTELHSLWQNEERAATVTKKTYEIWHRRHDYWLLAGIINHGYARWQDIQN 1754
RFMFNIADGGFTELH+LWQNEERAA + K EIWHRRHDYWLLAGI+ HGYARWQDIQN
Sbjct: 1706 RFMFNIADGGFTELHTLWQNEERAAISSGKLNEIWHRRHDYWLLAGIVLHGYARWQDIQN 1765
Query: 1755 DPRYAILNEPFKGEMNRGNFLEIKNKFLARRFKLLEQALVIEEQLRRAAYLNMSEDPSHP 1814
D ++AI+NEPFK E N+GNFLE+KNKFLARRFKLLEQALVIEEQLRRAAYLN+S++P+HP
Sbjct: 1766 DAQFAIINEPFKTEANKGNFLEMKNKFLARRFKLLEQALVIEEQLRRAAYLNLSQEPAHP 1825
Query: 1815 SMALNTRFAEVECLAESHQHLSKESMAGNKPANAVLHKVLKQLEELLSDMKADVTRLPAT 1874
+MAL+ RFAE ECLAESHQHLSKES+AGNKPANAVLHKVL QLEELLSDMKADVTRLPAT
Sbjct: 1826 AMALHARFAEAECLAESHQHLSKESLAGNKPANAVLHKVLNQLEELLSDMKADVTRLPAT 1885
Query: 1875 IARIPPVAVRLQMSERNILSRLANRAPEPTP 1905
++RIPP+A RLQMSER+ILSRLA++ EP P
Sbjct: 1886 LSRIPPIAARLQMSERSILSRLASKGTEPHP 1916
>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
[Homo sapiens]
Length = 1966
Score = 2621 bits (6793), Expect = 0.0
Identities = 1337/1924 (69%), Positives = 1532/1924 (79%), Gaps = 101/1924 (5%)
Query: 24 LNNSLPPPHPENEEDPEED---LSETETPKLKKKKKPKKPRDPKIPKSKRQKKERMLLCR 80
L S PP + P++D L + K+K+ PKK ++ K K +++KK
Sbjct: 18 LRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKR------ 71
Query: 81 QLGDSSGEGPEFVEEEEEVALRSDSEGSDYT--PGKKKKKKLGPKKEKKSKSKRKEEEEE 138
DS EF E +E +S+S GS+Y PG+K+++K KKEKK+K ++K E
Sbjct: 72 ---DSE---EEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKGEG-- 123
Query: 139 EDDDDDSKEPKSSAQLLEDWGMEDIDHVFSEEDYRTLTNYKAFSQFVRPLIAAKNPKIAV 198
D E KSSA LL WG+ED++HVFSEEDY TLTNYKAFSQF+RPLIA KNPKI +
Sbjct: 124 -DGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPM 182
Query: 199 SKMMMVLGAKWREFSTNNPFKGSSGASVAAAAAAAVAVVESMVTATEVA----------- 247
SKMM +LGAKWREFS NNPFKGS+ A AAAAAAA AV E + A A
Sbjct: 183 SKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPAL 242
Query: 248 PPPPPVEV---PIRKAKTKEGKGPNARRKPKGSPRVPDA-KKPKPKKVAPLKIKLGGFGS 303
PPPP ++ PIR+AKTKEGKGP +R+ K SPRVPD KK + KK+APLKIKLG G
Sbjct: 243 PPPPAADIQPPPIRRAKTKEGKGPGHKRRSK-SPRVPDGRKKLRGKKMAPLKIKLGLLGG 301
Query: 304 KRKRSSSEDDDLDV-------ESDFDDASINSYSVSDGSTSRSSRSRKKLRTTKKKK--- 353
KRK+ S D ESD D S++S S R+ + ++ KKKK
Sbjct: 302 KRKKGGSYVFQSDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVLG 361
Query: 354 ----KGEEEVTAVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHMVCLDPDMEKAPEGKW 409
GEEEV DGYETDHQDYCEVCQQGGEIILCDTCPRAYH+VCLDP++++APEGKW
Sbjct: 362 CPAVAGEEEV---DGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKW 418
Query: 410 SCPHCEKEGIQWEAKEDNSEGEEILEEVGGDLEEEDDHHMEFCRVCKDGGELLCCDTCPS 469
SCPHCEKEG+QWEAKE+ E EE EE G +EE+D HME+CRVCKDGGELLCCD C S
Sbjct: 419 SCPHCEKEGVQWEAKEEEEEYEEEGEEEGE--KEEEDDHMEYCRVCKDGGELLCCDACIS 476
Query: 470 SYHIHCLNPPLPEIPNGEWLCPRCTCPALKGKVQKILIWKWGQPPSPTPVPRPPDADPNT 529
SYHIHCLNPPLP+IPNGEWLCPRCTCP LKG+VQKIL W+WG+PP P P+ D +P+
Sbjct: 477 SYHIHCLNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDV 536
Query: 530 PSPKPLEGRPERQFFVKWQGMSYWHCSWVSELQLELHCQVMFRNYQRKNDMDEPPSGDFG 589
P P+PL+GR ER+FFVKW G+SYWHCSW ELQLE+ VM+RNYQRKNDMDEPP D+G
Sbjct: 537 PPPRPLQGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYG 596
Query: 590 GDEE--KSRKRKNKDPKFAEMEERFYRYGIKPEWMMIHRILNHSVDKKGHVHYLIKWRDL 647
E+ KS KRK KDP +AEMEE++YR+GIKPEWM +HRI+NHSVDKKG+ HYL+KWRDL
Sbjct: 597 SGEDDGKSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDL 656
Query: 648 PYDQASWESEDVEIQDYDLFKQSYWNHRELMRGEE-GRPGKKLKKVKLRKLERPPETPTV 706
PYDQ++WE +++ I +Y+ KQSYW HREL+ GE+ +P K KK K + + PP +PT
Sbjct: 657 PYDQSTWEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTN 716
Query: 707 DPTVKYERQPEYLDATGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLY 766
DPTVKYE QP ++ ATGGTLH YQ+EGLNWLRFSWAQGTDTILADEMGLGKT+QT VFLY
Sbjct: 717 DPTVKYETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLY 776
Query: 767 SLYKEGHSKGPFLVSAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDN 826
SLYKEGH+KGPFLVSAPLSTIINWEREF+MWAP YVVTY GDKDSRAIIRENEFSFEDN
Sbjct: 777 SLYKEGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDN 836
Query: 827 AIRGGKKASRMKKEASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFF 886
AI+GGKKA +MK+EA VKFHVLLTSYELITID A LGSI WACL+VDEAHRLKNNQSKFF
Sbjct: 837 AIKGGKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFF 896
Query: 887 RVLNGYSLQHKLLLTGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFADIAKEDQIKKL 946
RVLNGY + HKLLLTGTPLQNNLEELFHLLNFLTPERF+NLEGFLEEFADI+KEDQIKKL
Sbjct: 897 RVLNGYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKL 956
Query: 947 HDMLGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGGNQV 1006
HD+LGPHMLRRLKADVFKNMP+KTELIVRVELSPMQKKYYKYILTRNFEALN+RGGGNQV
Sbjct: 957 HDLLGPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQV 1016
Query: 1007 SLLNVVMDLKKCCNHPYLFPVAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKNLKEGG 1066
SLLN++MDLKKCCNHPYLFPVAAME+PK+P+G Y+G ALI++SGKL+LLQKML+ LKE G
Sbjct: 1017 SLLNIMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQG 1076
Query: 1067 HRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFCFLLST 1126
HRVLIFSQMTKMLDLLEDFL++EGYKYERIDGGITG +RQEAIDRFNAPGAQQFCFLLST
Sbjct: 1077 HRVLIFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLST 1136
Query: 1127 RAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQ 1186
RAGGLGINLATADTVII+DSDWNPHNDIQAFSRAHRIGQ KVMIYRFVTRASVEERITQ
Sbjct: 1137 RAGGLGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQ 1196
Query: 1187 VAKKKMMLTHLVVRPGLGSKTGSMSKQELDDILKFGTEELFKDEATDGGGDNKEGEDSSV 1246
VAK+KMMLTHLVVRPGLGSK GSMSKQELDDILKFGTEELFKDE G+NKE EDSSV
Sbjct: 1197 VAKRKMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDE---NEGENKE-EDSSV 1252
Query: 1247 IHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEEEVEREIIKQE 1306
IHYD++AI RLLDRNQD TEDT++Q MNEYLSSFKVAQYVVREE+ + EE+EREIIKQE
Sbjct: 1253 IHYDNEAIARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREED--KIEEIEREIIKQE 1310
Query: 1307 ESVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYNDGSQEDRDWQDDQSDNQSDY 1366
E+VDPDYWEKLLRHHYEQQQEDLARNLGKGKR+RKQVNYND +QED+ DNQS+Y
Sbjct: 1311 ENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQ-------DNQSEY 1363
Query: 1367 SVASEEGDEDFDERSEAPRRPSRKGLRNDKDKPLPPLLARVGGNIEVLGFNARQRKAFLN 1426
SV SEE DEDFDER E RR S++ LRN+KDKPLPPLLARVGGNIEVLGFN RQRKAFLN
Sbjct: 1364 SVGSEEEDEDFDERPEG-RRQSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLN 1422
Query: 1427 AIMRYGMPPQDAFTTQWLVRDLRGKSEKEFKAYVSLFMRHLCEPGADGAETFADGVPREG 1486
A+MR+GMPPQDAFTTQWLVRDLRGK+EKEFKAYVSLFMRHLCEPGADG+ETFADGVPREG
Sbjct: 1423 AVMRWGMPPQDAFTTQWLVRDLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREG 1482
Query: 1487 LSRQHVLTRIGVMSLIRKKVQEFEHVNGRWSMPEL-----AEVEENKKMSQPGSPSPKTP 1541
LSRQ VLTRIGVMSL++KKVQEFEH+NGRWSMPEL A+ + + + S P SP TP
Sbjct: 1483 LSRQQVLTRIGVMSLVKKKVQEFEHINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTP 1542
Query: 1542 TPSTPGDTQPNTPAPVPPAEDGIKIEENSLKEEESIEGEKEVKSTAPETAIECTQAPAPA 1601
S + PA P+E G I KEE + EK K++ +E T+A AP+
Sbjct: 1543 EASATNSPCTSKPATPAPSEKGEGIRTPLEKEEAENQEEKPEKNSRIGEKME-TEADAPS 1601
Query: 1602 SEDEKVVVEPPEGEEKVEKAEVKERTEEPMETEPKGAADVEKVEEKSAIDLTPIVVEDKE 1661
P E++E ++ P+E E G + E P D+E
Sbjct: 1602 --------PAPSLGERLEPRKI------PLEDEVPGVPGEMEPE--------PGYRGDRE 1639
Query: 1662 EKKEEEEKKEVMLQNGETPKDLNDEKQKKNIKQRFMFNIADGGFTELHSLWQNEERAATV 1721
+ ++ + +E+ + P+ N +++K K RFMFNIADGGFTELH+LWQNEERAA
Sbjct: 1640 KSEDVKGDRELRPGPRDEPRS-NGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAIS 1698
Query: 1722 TKKTYEIWHRRHDYWLLAGIINHGYARWQDIQNDPRYAILNEPFKGEMNRGNFLEIKNKF 1781
+ K EIWHRRHDYWLLAGI+ HGYARWQDIQND ++AI+NEPFK E N+GNFLE+KNKF
Sbjct: 1699 SGKLNEIWHRRHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKF 1758
Query: 1782 LARRFKLLEQALVIEEQLRRAAYLNMSEDPSHPSMALNTRFAEVECLAESHQHLSKESMA 1841
LARRFKLLEQALVIEEQLRRAAYLN+S++P+HP+MAL+ RFAE ECLAESHQHLSKES+A
Sbjct: 1759 LARRFKLLEQALVIEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLA 1818
Query: 1842 GNKPANAVLHKVLKQLEELLSDMKADVTRLPATIARIPPVAVRLQMSERNILSRLANRAP 1901
GNKPANAVLHKVL QLEELLSDMKADVTRLPAT++RIPP+A RLQMSER+ILSRLA++
Sbjct: 1819 GNKPANAVLHKVLNQLEELLSDMKADVTRLPATLSRIPPIAARLQMSERSILSRLASKGT 1878
Query: 1902 EPTP 1905
EP P
Sbjct: 1879 EPHP 1882
>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
[Homo sapiens]
Length = 1828
Score = 591 bits (1524), Expect = e-168
Identities = 415/1222 (33%), Positives = 621/1222 (50%), Gaps = 168/1222 (13%)
Query: 540 ERQFFVKWQGMSYWHCSWVSELQLE---LHCQVMFRNYQRKNDMDEPPSGDFGGDEEKSR 596
E Q+ +KW+G SY H +W SE L+ + N+++K D + G
Sbjct: 304 EIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLG---------- 353
Query: 597 KRKNKDPKFAEMEERFYRYGIKPEWMMIHRILNHSVDKK-----------------GHVH 639
K +D ++ ++ + ++ ++ R++ K
Sbjct: 354 KVSPEDVEYFNCQQELASE-LNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPE 412
Query: 640 YLIKWRDLPYDQASWESEDVEIQDYDLFKQSYWNHRELMRGEEGRPGKKLKKVKLRKLER 699
YL KW LPY + SWE E + + + S+ + + P ++ K +K +R
Sbjct: 413 YLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNN----SKTIPTRECKALK----QR 464
Query: 700 PPETPTVDPTVKYERQPEYLDATGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTV 759
P V ++QP YL L YQ+EGLNWL SW + ILADEMGLGKT+
Sbjct: 465 PR-------FVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTI 517
Query: 760 QTAVFLYSLYKEGHSKGPFLVSAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIREN 819
QT FL L+ + GPFL+ PLST+ +W+REFE+WAP++ VV Y+GD SR IRE
Sbjct: 518 QTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREY 577
Query: 820 EFSFEDNAIRGGKKASRMKKEASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLK 879
E+ S+ K+ +KF+ L+T+YE++ D +LGSI+WA L VDEAHRLK
Sbjct: 578 EWIH-----------SQTKR---LKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLK 623
Query: 880 NNQSKFFRVLNGYSLQHKLLLTGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFADIAK 939
N+ S ++ L + H+LL+TGTPLQN+L+EL+ LL+F+ PE+F E F E+ +
Sbjct: 624 NDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGK-GR 682
Query: 940 EDQIKKLHDMLGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNA 999
E+ + LH +L P +LRR+K DV K++P+K E I+RVE+S +QK+YYK+ILTRN++AL
Sbjct: 683 ENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAK 742
Query: 1000 RGGGNQVSLLNVVMDLKKCCNHPYLFPVAAMEAPKMPNGMYDGSALIRASGKLLLLQKML 1059
G+ LN+VM+LKKCCNH YL + E + NG +LIR+SGKL+LL K+L
Sbjct: 743 GTRGSTSGFLNIVMELKKCCNHCYL--IKPPEENERENGQEILLSLIRSSGKLILLDKLL 800
Query: 1060 KNLKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQ 1119
L+E G+RVLIFSQM +MLD+L ++L + Y ++R+DG I G +R++A+D FNA G++
Sbjct: 801 TRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSED 860
Query: 1120 FCFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRAS 1179
FCFLLSTRAGGLGINLA+ADTV+I+DSDWNP ND+QA +RAHRIGQ K+V IYR VT+ +
Sbjct: 861 FCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGT 920
Query: 1180 VEERITQVAKKKMMLTHLVV-------RPGLGSKTG-----SMSKQELDDILKFGTEELF 1227
VEE I + AKKKM+L HLV+ R L + +G +K+EL ILKFG E+LF
Sbjct: 921 VEEEIIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLF 980
Query: 1228 KDEATDGGGDNKEGEDSSVIHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVV 1287
K+ EGE+S D I RL + ++E + +E LS FKVA +
Sbjct: 981 KE---------LEGEESEPQEMDIDEILRLAETRENEVSTS---ATDELLSQFKVANFAT 1028
Query: 1288 REEEMGEEEEVEREIIKQEESVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYND 1347
E +EEE+E K + + P+ K + Q++ + L + + K+ ND
Sbjct: 1029 ME----DEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTND 1084
Query: 1348 GSQEDRDWQDDQSDNQSDYSVASEEGDEDFDERSEAPRRPSRKGLRNDKDKPLPPLLARV 1407
D +S Q+ S ASE ED D+ + RR + +R D
Sbjct: 1085 SD------SDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKDL----------- 1127
Query: 1408 GGNIEVLGFNARQRKAFLNAIMRYGMP-------PQDAFTTQWLVRDLRGKSEKEFKAYV 1460
V GF + + F+ A ++G+P +DA V DL+ E + V
Sbjct: 1128 -----VEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCV 1182
Query: 1461 SLFMRHLCEPGADGAETFADGVPREGLSRQHVLTRIGVMSLIRKKVQEFEHVNGRWSMPE 1520
S + + + +E G R G + + ++ V S+I+ + +EFE ++
Sbjct: 1183 SAMQEYEEQLKENASEGKGPG-KRRGPTIKISGVQVNVKSIIQHE-EEFEMLH------- 1233
Query: 1521 LAEVEENKKMSQPGSPSPKTPTPSTPGDTQPNTPAPVPPAEDG---IKIEENSLKEEESI 1577
S P P K T + +D + I E+ E I
Sbjct: 1234 ---------KSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELI 1284
Query: 1578 EGEKEVKSTAPETAIECTQAP----------------APASEDEKVVVEPPEGEEKVEKA 1621
+ + E+K T +E + P E + V E + K K
Sbjct: 1285 KTDPELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGLEKKGAVTGGEEAKLKKRKP 1344
Query: 1622 EVKERTEEPMETE--------PKGAADVEKVEEKSAIDLTPIVVEDKEEKKEEEEKKEVM 1673
VK+ + P E P+ + + + E L ++ K++KKE +E KE
Sbjct: 1345 RVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKENKEKQ 1404
Query: 1674 LQNGETPKDLNDEKQKKNIKQR 1695
+ + KD +K++K K +
Sbjct: 1405 M---SSRKDKEGDKERKKSKDK 1423
Score = 43.5 bits (101), Expect = 0.002
Identities = 35/141 (24%), Positives = 62/141 (43%), Gaps = 6/141 (4%)
Query: 53 KKKKPKKPRDPKIPKSKRQKKERMLLCRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTP 112
KK+KP+ ++ K+P+ K + + R + S EG + E+ ++ + +
Sbjct: 1340 KKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKE 1399
Query: 113 GKKK-----KKKLGPKKEKKSKSKRKEEEEEEDDDDDSKEPKSSAQLLEDWGMEDIDHVF 167
K+K K K G K+ KKSK K KE+ + D SK +S + G E +
Sbjct: 1400 NKEKQMSSRKDKEGDKERKKSKDK-KEKPKSGDAKSSSKSKRSQGPVHITAGSEPVPIGE 1458
Query: 168 SEEDYRTLTNYKAFSQFVRPL 188
E+D + + +RP+
Sbjct: 1459 DEDDDLDQETFSICKERMRPV 1479
Score = 40.8 bits (94), Expect = 0.013
Identities = 44/178 (24%), Positives = 71/178 (39%), Gaps = 36/178 (20%)
Query: 3 SGLGSPSPCSAGSEEEDMDALLNNSLPPPHPENEEDPEEDLSETETPKLKKKKKPKKPRD 62
SG GS S S+ S E ++ ++ P E E+ S+ E KK + P
Sbjct: 47 SGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDV 106
Query: 63 PKIPKSKRQKKE--RMLLCRQLGDSSGEGP-----------------EFVEEEEEVALRS 103
+ +S R ++E R + + S G E E+E+E +
Sbjct: 107 YGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSA 166
Query: 104 DSEGSDYTPGKKKKKKLGP------------KKEKKSKSKRKEEEEEEDDDDDSKEPK 149
+SE P +KK K P K+ K + KRK+++ ++DDDD + PK
Sbjct: 167 ESE-----PEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPK 219
Score = 37.7 bits (86), Expect = 0.11
Identities = 67/303 (22%), Positives = 120/303 (39%), Gaps = 41/303 (13%)
Query: 1503 RKKVQEFEHVNGRWSMPELAEVEENKKMSQPGSPSPKTPTPSTPGDTQPNTPAPVPPAED 1562
RKKV+E E E+EE + + S + K T + DT+ A A +
Sbjct: 1052 RKKVEEEERQK---------ELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASE 1102
Query: 1563 GIKIEENSLKEEESIEGEKEVKSTAPETAIECTQAPAPASEDEKVVVEPPEGEEKVEKAE 1622
+ E+S + +K + P + + +E + + + +E+ E
Sbjct: 1103 S--------ETEDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLE 1154
Query: 1623 VKERTEEPMETEPKGAADVEKVEEKSAIDLTPIVVEDKEEKKEE-EEKKEVMLQNGETPK 1681
R E ++ K AD++++ E + E +E+ KE E K + G T K
Sbjct: 1155 CIARDAELVD---KSVADLKRLGELIHNSCVSAMQEYEEQLKENASEGKGPGKRRGPTIK 1211
Query: 1682 DLNDEKQKKNIKQRFMFNIADGGFTELHS---LWQNEERAATVTKKT----YEI-WHRRH 1733
+ K+I Q + F LH + E++ +T + +++ W
Sbjct: 1212 ISGVQVNVKSIIQH------EEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVED 1265
Query: 1734 DYWLLAGIINHGYARWQDIQNDPRYAILNEPFKGEMNR---GNFLEIKNKFLARRFKLLE 1790
D LL GI HGY W+ I+ DP + ++ E ++ G L+ + +L KLL
Sbjct: 1266 DSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYL---LKLLR 1322
Query: 1791 QAL 1793
+ L
Sbjct: 1323 KGL 1325
Score = 36.6 bits (83), Expect = 0.24
Identities = 31/147 (21%), Positives = 66/147 (44%), Gaps = 16/147 (10%)
Query: 25 NNSLPPPHPENEEDPEEDLSETETPKLKKKKKPKKPRDPKIPKSKRQKKERMLLCRQLGD 84
N S P N ++ SE+ +PK + +++ KK K K++ E D
Sbjct: 113 NRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQE-----KWKQEPSE---------D 158
Query: 85 SSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKLGPKKEKKSKSKRKEEEEEEDDDDD 144
+G E E+ +++ T K + KK K ++ K K+++ +E+DDDD+
Sbjct: 159 EQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKK--QPKTQRGKRKKQDSSDEDDDDDE 216
Query: 145 SKEPKSSAQLLEDWGMEDIDHVFSEED 171
+ + ++ + ++ ++ D ++ D
Sbjct: 217 APKRQTRRRAAKNVSYKEDDDFETDSD 243
Score = 32.3 bits (72), Expect = 4.6
Identities = 11/24 (45%), Positives = 17/24 (70%)
Query: 635 KGHVHYLIKWRDLPYDQASWESED 658
+G + YLIKW+ Y ++WESE+
Sbjct: 302 EGEIQYLIKWKGWSYIHSTWESEE 325
>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
sapiens]
Length = 1710
Score = 569 bits (1466), Expect = e-161
Identities = 360/924 (38%), Positives = 520/924 (56%), Gaps = 98/924 (10%)
Query: 524 DADPNTPSPKPLEGRPERQFFVKWQGMSYWHCSWVSELQLE---LHCQVMFRNYQRKNDM 580
D DPN K E E Q+ +KW+G S+ H +W +E L+ + NY++K
Sbjct: 300 DGDPNAGFEKNKEPG-EIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKK--- 355
Query: 581 DEPPSGDFGGDEEKSRKRKNKDPKFAEME--ERFYRYGIKPEWMMIHRILNHSVDKK--G 636
D+E R KN P+ E ++ + ++ ++ RI+ HS K G
Sbjct: 356 ----------DQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAG 405
Query: 637 HVHYLIKWRDLPYDQASWESEDVEIQDYDLFKQSYWNHRELMRGEEGRPGKKLKKVKLRK 696
+ Y KW+ LPY + SWE + + + Y++ + + P K K +K
Sbjct: 406 YPDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQ----SKTTPFKDCKVLK--- 458
Query: 697 LERPPETPTVDPTVKYERQPEYLDATGGT-LHPYQMEGLNWLRFSWAQGTDTILADEMGL 755
+RP V ++QP Y+ G L YQ+ GLNWL SW +G ILADEMGL
Sbjct: 459 -QRPR-------FVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGL 510
Query: 756 GKTVQTAVFLYSLYKEGHSKGPFLVSAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAI 815
GKT+QT FL L+ E GPFL+ PLST+ +W+RE + WA M V Y+GD +SR +
Sbjct: 511 GKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNM 570
Query: 816 IRENEFSFEDNAIRGGKKASRMKKEASVKFHVLLTSYELITIDMAILGSIDWACLIVDEA 875
IR +E++ +KF++LLT+YE++ D A LG ++WA + VDEA
Sbjct: 571 IRTHEWTHHQTK--------------RLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEA 616
Query: 876 HRLKNNQSKFFRVLNGYSLQHKLLLTGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFA 935
HRLKN+ S ++ L + H+LL+TGTPLQN+L+EL+ LL+F+ PE+F + E F EE
Sbjct: 617 HRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHG 676
Query: 936 DIAKEDQIKKLHDMLGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFE 995
+E LH L P +LRR+K DV K++P+K E I+R+E+S +QK+YYK+ILTRN++
Sbjct: 677 K-GREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYK 735
Query: 996 ALNARGGGNQVSLLNVVMDLKKCCNHPYLFPVAAMEAPKMPNGMYDGSA----LIRASGK 1051
AL+ G+ LN++M+LKKCCNH YL P N Y+ LIR+SGK
Sbjct: 736 ALSKGSKGSTSGFLNIMMELKKCCNHCYLIK------PPDNNEFYNKQEALQHLIRSSGK 789
Query: 1052 LLLLQKMLKNLKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDR 1111
L+LL K+L L+E G+RVLIFSQM +MLD+L ++L++ + ++R+DG I G +R++A+D
Sbjct: 790 LILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDH 849
Query: 1112 FNAPGAQQFCFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMI 1171
FNA G++ FCFLLSTRAGGLGINLA+ADTV+I+DSDWNP ND+QA +RAHRIGQ K+V I
Sbjct: 850 FNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNI 909
Query: 1172 YRFVTRASVEERITQVAKKKMMLTHLVVR------------PGLGSKTGSMSKQELDDIL 1219
YR VT+ SVEE I + AKKKM+L HLV++ S + +K+EL IL
Sbjct: 910 YRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAIL 969
Query: 1220 KFGTEELFKDEATDGGGDNKEGEDSSVIHYDDKAIERLLDRNQ-DETEDTELQGMNEYLS 1278
KFG EELFK+ EGE+ D I+ +L R + E E L +E LS
Sbjct: 970 KFGAEELFKE---------PEGEEQEPQEMD---IDEILKRAETHENEPGPLTVGDELLS 1017
Query: 1279 SFKVAQYVVREEEMGEEEEVEREIIKQEESVDPDYWEKLLRHHYEQQQEDLARNLGKGKR 1338
FKVA + +E+ E E ER EE + D +L +++ E++ L + +
Sbjct: 1018 QFKVANFSNMDED-DIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYM-LPRMRN 1075
Query: 1339 IRKQVNYNDGSQEDRDWQDDQSDNQSDYSVASEEGDEDFDERSEAPRRPSRKGLRNDKDK 1398
KQ+++N GS+ R S + SD + EG ++ PR R+ ++ D
Sbjct: 1076 CAKQISFN-GSEGRRSRSRRYSGSDSD---SISEGKR--PKKRGRPRTIPRENIKGFSDA 1129
Query: 1399 PLPPLL---ARVGGNIEVLGFNAR 1419
+ + + GG +E L AR
Sbjct: 1130 EIRRFIKSYKKFGGPLERLDAIAR 1153
Score = 39.3 bits (90), Expect = 0.037
Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 11/96 (11%)
Query: 67 KSKRQKKERMLLCRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKLGPKKEK 126
K K+ K E + G S G + EEE D SDY P K K + P+
Sbjct: 140 KRKKHKDEDWQMSGS-GSPSQSGSDSESEEEREKSSCDETESDYEPKNKVKSR-KPQNRS 197
Query: 127 KSKSKRK---------EEEEEEDDDDDSKEPKSSAQ 153
KSK+ +K + EE+DD++D K S++
Sbjct: 198 KSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSR 233
Score = 32.3 bits (72), Expect = 4.6
Identities = 33/163 (20%), Positives = 67/163 (41%), Gaps = 28/163 (17%)
Query: 16 EEEDMDALLNNSLPPPHPENEEDPEEDLSETETPKLKKKKKPKKPRDPKIPKSKRQKKER 75
+ +D D ++ S P ++ + EE+ ++ + + +PK + P+++ + K
Sbjct: 143 KHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNG 202
Query: 76 MLLCRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKLGPKKEKKSKSKRKEE 135
+ G+ ++ EE D + DY K+ +++ KE+
Sbjct: 203 KKIL-------GQKKRQIDSSEE-----DDDEEDYDNDKRSS-----RRQATVNVSYKED 245
Query: 136 EEEEDDDDDSKEPKSSAQLLEDWGMEDIDHVFSEEDYRTLTNY 178
EE + D DD LLE G ED+ EE++ T+ +
Sbjct: 246 EEMKTDSDD---------LLEVCG-EDVPQP-EEEEFETIERF 277
>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
sapiens]
Length = 2997
Score = 531 bits (1369), Expect = e-150
Identities = 337/848 (39%), Positives = 469/848 (55%), Gaps = 114/848 (13%)
Query: 542 QFFVKWQGMSYWHCSWVSELQLELHCQVMFRNYQRKNDMDEPPSGDFGGDEEKSRKRKNK 601
+F+VK++ SY HC W S LE ++ + K K K
Sbjct: 825 EFYVKYKNFSYLHCQWASIEDLEKDKRIQ--------------------QKIKRFKAKQG 864
Query: 602 DPKF-AEMEERFYRYGIKPEWMMIHRILN--HSVDKKGH--VHYLIKWRDLPYDQASWES 656
KF +E+E+ + P+++ + RI++ S D +G HYL+KW LPY+ ++WE
Sbjct: 865 QNKFLSEIEDELFN----PDYVEVDRIMDFARSTDDRGEPVTHYLVKWCSLPYEDSTWER 920
Query: 657 EDVEIQDYDLFKQSYWNHRELMRGEEGRPGKKLKKVKLRKLERPPETPTVDPTVKYERQP 716
QD D K + +LM E + ++ERPP D K E
Sbjct: 921 R----QDIDQAKIEEFE--KLMSREP----------ETERVERPP----ADDWKKSESSR 960
Query: 717 EYLDATGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKG 776
EY + L YQ+EG+NWL F+W + ILADEMGLGKT+Q+ FLY +Y +G G
Sbjct: 961 EYKN--NNKLREYQLEGVNWLLFNWYNMRNCILADEMGLGKTIQSITFLYEIYLKG-IHG 1017
Query: 777 PFLVSAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASR 836
PFLV APLSTI NWEREF W ++ VV Y G + SR I+ E F+D R K
Sbjct: 1018 PFLVIAPLSTIPNWEREFRTWT-ELNVVVYHGSQASRRTIQLYEMYFKDPQGRVIK---- 1072
Query: 837 MKKEASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNGYSLQH 896
S KFH ++T++E+I D L +I W C+++DEAHRLKN K L L+H
Sbjct: 1073 ----GSYKFHAIITTFEMILTDCPELRNIPWRCVVIDEAHRLKNRNCKLLEGLKMMDLEH 1128
Query: 897 KLLLTGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFADIAKEDQIKKLHDMLGPHMLR 956
K+LLTGTPLQN +EELF LL+FL P RF + F++EF D+ E+Q++KL +L P MLR
Sbjct: 1129 KVLLTGTPLQNTVEELFSLLHFLEPSRFPSETTFMQEFGDLKTEEQVQKLQAILKPMMLR 1188
Query: 957 RLKADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGG-GNQVSLLNVVMDL 1015
RLK DV KN+ K E I+ VEL+ +QKKYY+ IL +NF L+ GG N +LLN +M+L
Sbjct: 1189 RLKEDVEKNLAPKEETIIEVELTNIQKKYYRAILEKNFTFLSKGGGQANVPNLLNTMMEL 1248
Query: 1016 KKCCNHPYLFPVAA-------MEAPKMPNGMYDGSALIRASGKLLLLQKMLKNLKEGGHR 1068
+KCCNHPYL A E + + A+I+A+GKL+L+ K+L LK GGHR
Sbjct: 1249 RKCCNHPYLINGAEEKILEEFKETHNAESPDFQLQAMIQAAGKLVLIDKLLPKLKAGGHR 1308
Query: 1069 VLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFCFLLSTRA 1128
VLIFSQM + LD+LED+L Y YERIDG + GN+RQ AIDRF+ P + +F FLL TRA
Sbjct: 1309 VLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRA 1368
Query: 1129 GGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVA 1188
GGLGINL ADT II+DSDWNP ND+QA +R HRIGQ+K V IYR +TR S E + A
Sbjct: 1369 GGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKA 1428
Query: 1189 KKKMMLTHLVVRPGLGSKTGS-----MSKQELDDILKFGTEELFKDEATDGGGDNKEGED 1243
K+ L V++ G + + +SK+E++D+L+ G DE +G +E D
Sbjct: 1429 SLKLGLDKAVLQSMSGRENATNGVQQLSKKEIEDLLRKGAYGALMDEEDEGSKFCEEDID 1488
Query: 1244 SSVIHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEEEVEREII 1303
+ LL R T ++E +G S+F A +V G ++ +
Sbjct: 1489 -----------QILLRRTHTITIESEGKG-----STFAKASFVA----SGNRTDISLD-- 1526
Query: 1304 KQEESVDPDYWEKLLRHHYEQQQEDLARNLGKGK------RIRKQVNYNDGSQEDR--DW 1355
DP++W+K + + + D+ G+ R+RKQ +ED ++
Sbjct: 1527 ------DPNFWQKWAK----KAELDIDALNGRNNLVIDTPRVRKQTRLYSAVKEDELMEF 1576
Query: 1356 QDDQSDNQ 1363
D +SD++
Sbjct: 1577 SDLESDSE 1584
Score = 48.1 bits (113), Expect = 8e-05
Identities = 37/146 (25%), Positives = 66/146 (45%), Gaps = 25/146 (17%)
Query: 42 DLSETETPKLKKKKKPKKPRDPKIPKSKRQKKERMLLCRQLGDSSGEGPEFVEEEEEVAL 101
D S+ E K K+ K K P++PK PK K++ KE + + P+ +E +E
Sbjct: 635 DGSQEEKKKKKRSKAKKDPKEPKEPKEKKEPKE---------PKTPKAPKIPKEPKEKKA 685
Query: 102 RSDS---EGSDYTPGKKKKKKLGPKKEKKSKSKRKEEEE-------------EEDDDDDS 145
++ + + S + KK + K+K +K K + E EED+D
Sbjct: 686 KTATPKPKSSKKSSNKKPDSEASALKKKVNKGKTEGSENSDLDKTPPPSPPPEEDEDPGV 745
Query: 146 KEPKSSAQLLEDWGMEDIDHVFSEED 171
++ +SS Q+ ED++ S+E+
Sbjct: 746 QKRRSSRQVKRKRYTEDLEFKISDEE 771
>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
sapiens]
Length = 2881
Score = 520 bits (1340), Expect = e-147
Identities = 332/861 (38%), Positives = 476/861 (55%), Gaps = 126/861 (14%)
Query: 542 QFFVKWQGMSYWHCSWVSELQLELHCQVMFRNYQRKNDMDEPPSGDFGGDEEKSRKRKNK 601
+FFVK++ SY HC W +E QL ++ ++K ++ K +
Sbjct: 715 EFFVKYKNYSYLHCEWATEEQLLKDKRI----------------------QQKIKRFKLR 752
Query: 602 DPK----FAEMEERFYRYGIKPEWMMIHRILNHSV--DK---KGHVHYLIKWRDLPYDQA 652
+ FA+MEE + P+++ + R+L S DK + ++YL+KW LPY+ +
Sbjct: 753 QAQRAHFFADMEEEPFN----PDYVEVDRVLEVSFCEDKDTGEPVIYYLVKWCSLPYEDS 808
Query: 653 SWE-SEDVEIQDYDLFKQSYWNHRELMRGEEGRPGKKLKKVKLRKLERPPET--PTVDPT 709
+WE EDV++ + F+Q + RP R+L+RPP +D +
Sbjct: 809 TWELKEDVDLAKIEEFEQL----------QASRPDT-------RRLDRPPSNIWKKIDQS 851
Query: 710 VKYERQPEYLDATGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLY 769
Y+ G L YQ+EGLNWL F+W + ILADEMGLGKT+Q+ FLY +
Sbjct: 852 RDYKN--------GNQLREYQLEGLNWLLFNWYNRRNCILADEMGLGKTIQSITFLYEIL 903
Query: 770 KEGHSKGPFLVSAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIR 829
G +GPFL+ APLSTI NWEREF W D+ VV Y G SR +I++ E F D+ R
Sbjct: 904 LTG-IRGPFLIIAPLSTIANWEREFRTWT-DINVVVYHGSLISRQMIQQYEMYFRDSQGR 961
Query: 830 GGKKASRMKKEASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVL 889
+ A R F ++T++E+I L +I+W C+I+DEAHRLKN K L
Sbjct: 962 IIRGAYR--------FQAIITTFEMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGL 1013
Query: 890 NGYSLQHKLLLTGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFADIAKEDQIKKLHDM 949
+L+HK+LLTGTPLQN +EELF LL+FL P RF + F++EF D+ E+Q++KL +
Sbjct: 1014 KLMNLEHKVLLTGTPLQNTVEELFSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAI 1073
Query: 950 LGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGGNQV-SL 1008
L P MLRRLK DV K + K E I+ VEL+ +QKKYY+ IL +NF L+ G V +L
Sbjct: 1074 LKPMMLRRLKEDVEKKLAPKEETIIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNL 1133
Query: 1009 LNVVMDLKKCCNHPYLFPVAAMEAPKMPNGMYDGSA-------LIRASGKLLLLQKMLKN 1061
+N +M+L+KCCNHPYL A + Y+ +A +I+++GKL+L+ K+L
Sbjct: 1134 VNTMMELRKCCNHPYLIKGAEEKILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPK 1193
Query: 1062 LKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFC 1121
+K GGH+VLIFSQM + LD+LED+L H+ Y YERIDG + GN+RQ AIDRF+ P + +F
Sbjct: 1194 MKAGGHKVLIFSQMVRCLDILEDYLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFV 1253
Query: 1122 FLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVE 1181
FLL TRAGGLGINL ADT II+DSDWNP ND+QA +R HRIGQNK V +YR VTR S E
Sbjct: 1254 FLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYE 1313
Query: 1182 ERITQVAKKKMMLTHLVVRPGLGSKTG-----SMSKQELDDILKFGTEELFKDEATDGGG 1236
+ A K+ L V++ G ++ +SK+E++D+L+ G +E +G
Sbjct: 1314 REMFDRASLKLGLDKAVLQSMSGRESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSK 1373
Query: 1237 DNKEGEDSSVIHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEE 1296
+E D + LL R + T ++E +G S+F A +V G
Sbjct: 1374 FCEEDID-----------QILLRRTKTITIESEGRG-----STFAKASFVA----SGNRT 1413
Query: 1297 EVEREIIKQEESVDPDYWEKLLRHHYEQQQEDLARN--LGKGKRIRKQVNYNDGSQEDRD 1354
++ + DP++W+K + + RN + RIRKQ ++
Sbjct: 1414 DISLD--------DPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRPFSATK---- 1461
Query: 1355 WQDDQSDNQSDYSVASEEGDE 1375
D ++ S A EGDE
Sbjct: 1462 ------DELAELSEAESEGDE 1476
Score = 41.2 bits (95), Expect = 0.010
Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 9/102 (8%)
Query: 264 EGKGPNARRKPKGSPRVPDAKKPKPKKVAPLKIKLG----GFGSKRKRSSSEDDDLDVES 319
EGK R+ K P+ D+KK K K K+G G K+KR + D++ S
Sbjct: 560 EGKEEKKGRRMKSKPKDKDSKKTKTCSKLKEKTKIGKLIITLGKKQKRKNESSDEI---S 616
Query: 320 DFDDASINSYSVSDGSTSRSSR--SRKKLRTTKKKKKGEEEV 359
D + ++ D RS+R RKK + K+ EEEV
Sbjct: 617 DAEQMPQHTLKDQDSQKRRSNRQIKRKKYAEDIEGKQSEEEV 658
Score = 32.7 bits (73), Expect = 3.5
Identities = 34/165 (20%), Positives = 63/165 (38%), Gaps = 39/165 (23%)
Query: 43 LSETETPKLKKKKKPKKPRDPKIPKSKRQKKERMLLCRQLGDSSGEGPEFVEE--EEEVA 100
L T+ + +KK+ KK + +Q+K ++ + + G + E
Sbjct: 500 LQNTQVRVMSEKKQRKK-----VESESKQEKANRIISEAIAKAKERGERNIPRVMSPENF 554
Query: 101 LRSDSEGSDYTPGKKKKKKLGPKKEKKSKS-------------------KRKEEEEEEDD 141
+ EG + G++ K K K KK+K+ K+K + E D+
Sbjct: 555 PTASVEGKEEKKGRRMKSKPKDKDSKKTKTCSKLKEKTKIGKLIITLGKKQKRKNESSDE 614
Query: 142 -------------DDDSKEPKSSAQLLEDWGMEDIDHVFSEEDYR 173
D DS++ +S+ Q+ EDI+ SEE+ +
Sbjct: 615 ISDAEQMPQHTLKDQDSQKRRSNRQIKRKKYAEDIEGKQSEEEVK 659
>gi|29244924 chromodomain helicase DNA binding protein 6 [Homo
sapiens]
Length = 2715
Score = 519 bits (1336), Expect = e-146
Identities = 344/963 (35%), Positives = 504/963 (52%), Gaps = 146/963 (15%)
Query: 543 FFVKWQGMSYWHCSWVSELQLELHCQVMFRNYQRKNDMDEPPSGDFGGDEEKSRKRKNKD 602
F+VK++ SY HC W + +LE ++ +K ++ +NK
Sbjct: 318 FYVKYRNFSYLHCKWATMEELEKDPRIA----------------------QKIKRFRNKQ 355
Query: 603 PK----FAEMEERFYRYGIKPEWMMIHRILNHSVDKKGHV-----HYLIKWRDLPYDQAS 653
+ F E +E + P+++ + RIL + K HYL+KW LPY++++
Sbjct: 356 AQMKHIFTEPDEDLFN----PDYVEVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEEST 411
Query: 654 WESEDVEIQDYDLFKQSYWNHRELMRGEEGRPGKKLKKVKLRKLERPPETPTVDPTVKYE 713
WE E+ D D K + +++ +++ +ERP D K E
Sbjct: 412 WELEE----DVDPAKVKEFESLQVLP-------------EIKHVERPAS----DSWQKLE 450
Query: 714 RQPEYLDATGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGH 773
+ EY ++ L YQ+EG+NWL F+W + ILADEMGLGKT+Q+ FL ++ G
Sbjct: 451 KSREYKNSN--QLREYQLEGMNWLLFNWYNRKNCILADEMGLGKTIQSITFLSEIFLRG- 507
Query: 774 SKGPFLVSAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKK 833
GPFL+ APLSTI NWEREF W +M + Y G + SR +I++ E + D
Sbjct: 508 IHGPFLIIAPLSTITNWEREFRTWT-EMNAIVYHGSQISRQMIQQYEMVYRD-------- 558
Query: 834 ASRMKKEASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNGYS 893
A KFHV++T++E+I D L I W+C+I+DEAHRLKN K L +
Sbjct: 559 AQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAHRLKNRNCKLLEGLKLMA 618
Query: 894 LQHKLLLTGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFADIAKEDQIKKLHDMLGPH 953
L+HK+LLTGTPLQN++EELF LLNFL P +F + FLEEF D+ E+Q+KKL +L P
Sbjct: 619 LEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGDLKTEEQVKKLQSILKPM 678
Query: 954 MLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGG-NQVSLLNVV 1012
MLRRLK DV KN+ K E I+ VEL+ +QKKYY+ IL +NF L N +L+N +
Sbjct: 679 MLRRLKDDVEKNLAPKQETIIEVELTNIQKKYYRAILEKNFSFLTKGANQHNMPNLINTM 738
Query: 1013 MDLKKCCNHPYLFPVAAME---------APKMPNGMYDGSALIRASGKLLLLQKMLKNLK 1063
M+L+KCCNHPYL A + +P P+ + A+I+A+GKL+L+ K+L L
Sbjct: 739 MELRKCCNHPYLINGAEEKILEDFRKTHSPDAPD--FQLQAMIQAAGKLVLIDKLLPKLI 796
Query: 1064 EGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFCFL 1123
GGH+VLIFSQM + LD+LED+L Y YERIDG + GN+RQ AIDRF P + +F FL
Sbjct: 797 AGGHKVLIFSQMVRCLDILEDYLIQRRYTYERIDGRVRGNLRQAAIDRFCKPDSDRFVFL 856
Query: 1124 LSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEER 1183
L TRAGGLGINL ADT II+DSDWNP ND+QA +R HRIGQ+K V +YR +TR S E
Sbjct: 857 LCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYERE 916
Query: 1184 ITQVAKKKMMLTHLVV----RPGLGSKTGSMSKQELDDILKFGTEELFKDEATDGGGDNK 1239
+ A K+ L V+ R G + +SK E++D+L+ G DE +G
Sbjct: 917 MFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEVEDLLRKGAYGALMDEEDEGS---- 972
Query: 1240 EGEDSSVIHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEEEVE 1299
+ ++ I+++L R + T + +G S+F A +V G ++
Sbjct: 973 --------KFCEEDIDQILQR-RTHTITIQSEGKG---STFAKASFVA----SGNRTDIS 1016
Query: 1300 REIIKQEESVDPDYWEKL-----LRHHYEQQQEDLARNLGKGKRIRKQVNYNDGSQEDRD 1354
+ DP++W+K L + ++E L + R+RKQ + + +ED
Sbjct: 1017 LD--------DPNFWQKWAKIAELDTEAKNEKESLVID---RPRVRKQTKHYNSFEEDEL 1065
Query: 1355 WQDDQSDNQSDYSVASEEGDEDFDERSEAPRRPSRKGLRNDKDKP-LPPLLARVGGNIEV 1413
+ + D+ SD RP+R NDK + L RV N+ +
Sbjct: 1066 MEFSELDSDSD-------------------ERPTRSRRLNDKARRYLRAECFRVEKNLLI 1106
Query: 1414 LGFNARQRKAFLNAIMRYGMPPQDAFTTQWLVRDLRGKSEKEFKA--YVSLFMRHLCEPG 1471
G+ R + + ++ + +D + + R L K +K + F+ L P
Sbjct: 1107 FGW-GRWKDILTHGRFKWHLNEKD---MEMICRALLVYCVKHYKGDEKIKSFIWELITPT 1162
Query: 1472 ADG 1474
DG
Sbjct: 1163 KDG 1165
Score = 54.3 bits (129), Expect = 1e-06
Identities = 42/153 (27%), Positives = 69/153 (45%), Gaps = 21/153 (13%)
Query: 44 SETETPKLKKKKKPKKPRDPKIPKSKRQKKERMLLCRQLGDSSGEGP-EFVEEEEEVALR 102
S+ PK K+K++PK+P++P+ K ++ KE ++ G P E +E R
Sbjct: 111 SKDREPKPKRKREPKEPKEPRKAKEPKKAKEHKEPKQKDGAKKARKPREASGTKEAKEKR 170
Query: 103 SDSEGSDYTPGKKKKKKLGPKK-EKKSKSKRKEE-------------------EEEEDDD 142
S ++ + T +K K+ GP EKK K KRK E EE +
Sbjct: 171 SCTDSAARTKSRKASKEQGPTPVEKKKKGKRKSETTVESLELDQGLTNPSLRSPEESTES 230
Query: 143 DDSKEPKSSAQLLEDWGMEDIDHVFSEEDYRTL 175
DS++ +S Q+ ED+D ++D T+
Sbjct: 231 TDSQKRRSGRQVKRRKYNEDLDFKVVDDDGETI 263
Score = 32.7 bits (73), Expect = 3.5
Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 9/59 (15%)
Query: 104 DSEGSDYTPGKKKKKKLGP---------KKEKKSKSKRKEEEEEEDDDDDSKEPKSSAQ 153
+ G T KKK+KK P K+++ K KRK E +E + +KEPK + +
Sbjct: 83 EDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKAKEPKKAKE 141
>gi|114326455 chromodomain helicase DNA binding protein 8 [Homo
sapiens]
Length = 2302
Score = 512 bits (1319), Expect = e-144
Identities = 330/862 (38%), Positives = 456/862 (52%), Gaps = 121/862 (14%)
Query: 542 QFFVKWQGMSYWHCSWVSELQLELHCQVMFRNYQRKNDMDEPPSGDFGGDEEKSRKRKNK 601
+FFVK++ SY HC W + QLE D+ +K K
Sbjct: 388 EFFVKYKNYSYLHCEWATISQLEK-------------------------DKRIHQKLKRF 422
Query: 602 DPKFAEMEERFYR--YGIKPEWMMIHRILN--HSVDKKGH---VHYLIKWRDLPYDQASW 654
K A+M F+ P+++ + RIL+ HS+DK ++YL+KW LPY+ ++W
Sbjct: 423 KTKMAQMRHFFHEDEEPFNPDYVEVDRILDESHSIDKDNGEPVIYYLVKWCSLPYEDSTW 482
Query: 655 E-SEDVEIQDYDLFKQSYWNHRELMRGEEGRPGKKLKKVKLRKLERPPETPTVDPTVKYE 713
E EDV+ FK+ H EL R P K E
Sbjct: 483 ELKEDVDEGKIREFKRIQSRHPELKRVNR---------------------PQASAWKKLE 521
Query: 714 RQPEYLDATGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGH 773
EY + L YQ+EG+NWL F+W + ILADEMGLGKT+Q+ FL +Y G
Sbjct: 522 LSHEYKNRN--QLREYQLEGVNWLLFNWYNRQNCILADEMGLGKTIQSIAFLQEVYNVG- 578
Query: 774 SKGPFLVSAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKK 833
GPFLV APLSTI NWEREF W +M + Y G SR +I++ E +D+ R
Sbjct: 579 IHGPFLVIAPLSTITNWEREFNTWT-EMNTIVYHGSLASRQMIQQYEMYCKDSRGR---- 633
Query: 834 ASRMKKEASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNGYS 893
+ KF L+T++E+I D L I+W C+I+DEAHRLKN K L
Sbjct: 634 ----LIPGAYKFDALITTFEMILSDCPELREIEWRCVIIDEAHRLKNRNCKLLDSLKHMD 689
Query: 894 LQHKLLLTGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFADIAKEDQIKKLHDMLGPH 953
L+HK+LLTGTPLQN +EELF LL+FL P +F + FL++F D+ E+Q++KL +L P
Sbjct: 690 LEHKVLLTGTPLQNTVEELFSLLHFLEPSQFPSESEFLKDFGDLKTEEQVQKLQAILKPM 749
Query: 954 MLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGG-NQVSLLNVV 1012
MLRRLK DV KN+ K E I+ VEL+ +QKKYY+ IL +NF L+ G N +LLN +
Sbjct: 750 MLRRLKEDVEKNLAPKQETIIEVELTNIQKKYYRAILEKNFSFLSKGAGHTNMPNLLNTM 809
Query: 1013 MDLKKCCNHPYLFPVAA-------MEAPKMPNGMYDGSALIRASGKLLLLQKMLKNLKEG 1065
M+L+KCCNHPYL A EA + + A++R++GKL+L+ K+L LK G
Sbjct: 810 MELRKCCNHPYLINGAEEKILTEFREACHIIPHDFHLQAMVRSAGKLVLIDKLLPKLKAG 869
Query: 1066 GHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFCFLLS 1125
GH+VLIFSQM + LD+LED+L Y YERIDG + GN+RQ AIDRF+ P + +F FLL
Sbjct: 870 GHKVLIFSQMVRCLDILEDYLIQRRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLC 929
Query: 1126 TRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERIT 1185
TRAGGLGINL ADT II+DSDWNP ND+QA +R HRIGQ+K V +YR +TR S E +
Sbjct: 930 TRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMF 989
Query: 1186 QVAKKKMMLTHLVV-----RPGLGSKTGSMSKQELDDILKFGTEELFKDEATDGGGDNKE 1240
A K+ L V+ R G + SK+E++D+L+ G +E +G +E
Sbjct: 990 DKASLKLGLDKAVLQSMSGRDGNITGIQQFSKKEIEDLLRKGAYAAIMEEDDEGSKFCEE 1049
Query: 1241 GEDSSVIHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEEEVER 1300
D + LL R T ++E +G S+F A +V E +
Sbjct: 1050 DID-----------QILLRRTTTITIESEGKG-----STFAKASFVASENRTDISLD--- 1090
Query: 1301 EIIKQEESVDPDYWEKLLRHHYEQQQEDLARNLGKGK--------RIRKQVNYNDGSQED 1352
DP++W+K + + DL +L K R+RKQ + ++D
Sbjct: 1091 ---------DPNFWQKWAK------KADLDMDLLNSKNNLVIDTPRVRKQTRHFSTLKDD 1135
Query: 1353 RDWQDDQSDNQSDYSVASEEGD 1374
+ +++ D S D
Sbjct: 1136 DLVEFSDLESEDDERPRSRRHD 1157
Score = 37.7 bits (86), Expect = 0.11
Identities = 37/151 (24%), Positives = 65/151 (43%), Gaps = 10/151 (6%)
Query: 1552 NTPAPVPPAEDGIKIEENSLKEEESIEGEKEVKSTAPETAIECTQA----PAPASEDEKV 1607
++PA P G E + + E + EK + A A + P +EDE
Sbjct: 152 SSPASSAPHSGGKTGMEENRRLEHQKKQEKANRIVAEAIARARARGEQNIPRVLNEDELP 211
Query: 1608 VVEP-PEGEEKVEKAEVKER--TEEPMETEPKGAADVEKVEEKSAIDLTPIVVEDKEEKK 1664
V P EGE+K K ER E+P +++ GA+ K + KS ++ VV K ++
Sbjct: 212 SVRPEEEGEKKRRKKSAGERLKEEKPKKSKTSGAS---KTKGKSKLNTITPVVGKKRKRN 268
Query: 1665 EEEEKKEVMLQNGETPKDLNDEKQKKNIKQR 1695
+ +V + ++P++ + +K R
Sbjct: 269 TSSDNSDVEVMPAQSPREDEESSIQKRRSNR 299
Score = 35.4 bits (80), Expect = 0.54
Identities = 35/166 (21%), Positives = 73/166 (43%), Gaps = 35/166 (21%)
Query: 16 EEEDMDALLNNSLPPPHPENEEDPEEDLSETETPKLKKKKKPKKPRDPKIPKSKRQKKER 75
++E + ++ ++ E++ L+E E P ++ +++ +K KR+KK
Sbjct: 178 KQEKANRIVAEAIARARARGEQNIPRVLNEDELPSVRPEEEGEK---------KRRKK-- 226
Query: 76 MLLCRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKLGP---KKEKKSKSKR 132
S+GE +EE +S + G+ T GK K + P KK K++ S
Sbjct: 227 ---------SAGE-----RLKEEKPKKSKTSGASKTKGKSKLNTITPVVGKKRKRNTSSD 272
Query: 133 KEEEE-------EEDDDDDSKEPKSSAQLLEDWGMEDIDHVFSEED 171
+ E ED++ ++ +S+ Q+ ED+D ++++
Sbjct: 273 NSDVEVMPAQSPREDEESSIQKRRSNRQVKRKKYTEDLDIKITDDE 318
>gi|164419749 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a1 isoform b [Homo sapiens]
Length = 1042
Score = 428 bits (1101), Expect = e-119
Identities = 276/793 (34%), Positives = 422/793 (53%), Gaps = 100/793 (12%)
Query: 705 TVDPTVKYERQPEYLDATGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVF 764
T + +++E P Y+ GG L YQ+ GLNWL + G + ILADEMGLGKT+QT
Sbjct: 164 TSNVCIRFEVSPSYVK--GGPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIAL 221
Query: 765 LYSLYKEGHSKGPFLVSAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFE 824
L L + GP +V P ST+ NW EF+ W P + V+ +VGDKD+RA
Sbjct: 222 LGYLKHYRNIPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDARAAF------IR 275
Query: 825 DNAIRGGKKASRMKKEASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSK 884
D + G ++ V +TSYE++ + ++ W L++DEAHR+KN +SK
Sbjct: 276 DEMMPG-------------EWDVCVTSYEMVIKEKSVFKKFHWRYLVIDEAHRIKNEKSK 322
Query: 885 FFRVLNGYSLQHKLLLTGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFAD---IAKED 941
++ + ++LLLTGTPLQNNL EL+ LLNFL P+ F++ + F F + +
Sbjct: 323 LSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQK 382
Query: 942 QIKKLHDMLGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARG 1001
+++LH +L P +LRR+K DV K++P K E+ + + LS MQ+++Y IL ++ + LN+ G
Sbjct: 383 LVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSG 442
Query: 1002 GGNQVSLLNVVMDLKKCCNHPYLFPVAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKN 1061
+++ LLN++M L+KCCNHPYLF A P + ++ SGK+++L K+L
Sbjct: 443 KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTD-----EHIVSNSGKMVVLDKLLAK 497
Query: 1062 LKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFC 1121
LKE G RVLIFSQMT++LD+LED+ GY+Y R+DG R+EAI+ FNAP + +F
Sbjct: 498 LKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEEREEAIEAFNAPNSSKFI 557
Query: 1122 FLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVE 1181
F+LSTRAGGLGINLA+AD VI+YDSDWNP D+QA RAHRIGQ K V ++R +T +VE
Sbjct: 558 FMLSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVE 617
Query: 1182 ERITQVAKKKMMLTHLVVRPG--LGSKTGSMSKQELDDILKFGTEELFKDEATDGGGDNK 1239
ERI + A+ K+ L +V++ G + ++ ++K+E+ +++ G +F +K
Sbjct: 618 ERIVERAEIKLRLDSIVIQQGRLIDQQSNKLAKEEMLQMIRHGATHVFA---------SK 668
Query: 1240 EGEDSSVIHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEEEV- 1298
E E D+ I +L+R + +T + MNE L K+ + +R M E+ +
Sbjct: 669 ESE------LTDEDITTILERGEKKTAE-----MNERLQ--KMGESSLRNFRMDIEQSLY 715
Query: 1299 --------EREIIKQEESVDPDYWEKLLRHHYEQQQEDLAR----NLGKGKRIRKQVNYN 1346
E++ + E ++P E+ + + + R + K R KQ N
Sbjct: 716 KFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRPPKQPNV- 774
Query: 1347 DGSQEDRDWQDDQSDNQSDYSVASEE-------------GDEDFDERSEAPRRPSRKGLR 1393
QD Q + + +E + D + A R +K
Sbjct: 775 ---------QDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKK--- 822
Query: 1394 NDKDKPLPPLLARVGGNIEVLGF---NARQRKAFLNAIMRYGMPPQDAFTTQWLVRDLRG 1450
D +PL P + GF R F+ A +YG D + R++ G
Sbjct: 823 IDGAEPLTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDN-----IAREVEG 877
Query: 1451 KSEKEFKAYVSLF 1463
KS +E Y ++F
Sbjct: 878 KSPEEVMEYSAVF 890
>gi|21071044 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a1 isoform a [Homo sapiens]
Length = 1054
Score = 419 bits (1078), Expect = e-116
Identities = 276/805 (34%), Positives = 422/805 (52%), Gaps = 112/805 (13%)
Query: 705 TVDPTVKYERQPEYLDATGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVF 764
T + +++E P Y+ GG L YQ+ GLNWL + G + ILADEMGLGKT+QT
Sbjct: 164 TSNVCIRFEVSPSYVK--GGPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIAL 221
Query: 765 LYSLYKEGHSKGPFLVSAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFE 824
L L + GP +V P ST+ NW EF+ W P + V+ +VGDKD+RA
Sbjct: 222 LGYLKHYRNIPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDARAAF------IR 275
Query: 825 DNAIRGGKKASRMKKEASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSK 884
D + G ++ V +TSYE++ + ++ W L++DEAHR+KN +SK
Sbjct: 276 DEMMPG-------------EWDVCVTSYEMVIKEKSVFKKFHWRYLVIDEAHRIKNEKSK 322
Query: 885 FFRVLNGYSLQHKLLLTGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFAD---IAKED 941
++ + ++LLLTGTPLQNNL EL+ LLNFL P+ F++ + F F + +
Sbjct: 323 LSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQK 382
Query: 942 QIKKLHDMLGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARG 1001
+++LH +L P +LRR+K DV K++P K E+ + + LS MQ+++Y IL ++ + LN+ G
Sbjct: 383 LVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSG 442
Query: 1002 GGNQVSLLNVVMDLKKCCNHPYLFPVAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKN 1061
+++ LLN++M L+KCCNHPYLF A P + ++ SGK+++L K+L
Sbjct: 443 KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTD-----EHIVSNSGKMVVLDKLLAK 497
Query: 1062 LKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQ------------EAI 1109
LKE G RVLIFSQMT++LD+LED+ GY+Y R+DG R+ EAI
Sbjct: 498 LKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEEREDKFLEVEFLGQREAI 557
Query: 1110 DRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKV 1169
+ FNAP + +F F+LSTRAGGLGINLA+AD VI+YDSDWNP D+QA RAHRIGQ K V
Sbjct: 558 EAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRAHRIGQKKPV 617
Query: 1170 MIYRFVTRASVEERITQVAKKKMMLTHLVVRPG--LGSKTGSMSKQELDDILKFGTEELF 1227
++R +T +VEERI + A+ K+ L +V++ G + ++ ++K+E+ +++ G +F
Sbjct: 618 RVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKLAKEEMLQMIRHGATHVF 677
Query: 1228 KDEATDGGGDNKEGEDSSVIHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVV 1287
+KE E D+ I +L+R + +T + MNE L K+ + +
Sbjct: 678 A---------SKESE------LTDEDITTILERGEKKTAE-----MNERLQ--KMGESSL 715
Query: 1288 REEEMGEEEEV---------EREIIKQEESVDPDYWEKLLRHHYEQQQEDLAR----NLG 1334
R M E+ + E++ + E ++P E+ + + + R +
Sbjct: 716 RNFRMDIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIP 775
Query: 1335 KGKRIRKQVNYNDGSQEDRDWQDDQSDNQSDYSVASEE-------------GDEDFDERS 1381
K R KQ N QD Q + + +E + D +
Sbjct: 776 KAPRPPKQPNV----------QDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPA 825
Query: 1382 EAPRRPSRKGLRNDKDKPLPPLLARVGGNIEVLGF---NARQRKAFLNAIMRYGMPPQDA 1438
A R +K D +PL P + GF R F+ A +YG D
Sbjct: 826 LAQREEQKK---IDGAEPLTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDN 882
Query: 1439 FTTQWLVRDLRGKSEKEFKAYVSLF 1463
+ R++ GKS +E Y ++F
Sbjct: 883 -----IAREVEGKSPEEVMEYSAVF 902
>gi|21071058 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a5 [Homo sapiens]
Length = 1052
Score = 415 bits (1066), Expect = e-115
Identities = 250/655 (38%), Positives = 373/655 (56%), Gaps = 66/655 (10%)
Query: 711 KYERQPEYLDATGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYK 770
++E P Y+ G L YQ+ GLNWL + G + ILADEMGLGKT+QT L +
Sbjct: 167 RFEDSPSYVK--WGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKH 224
Query: 771 EGHSKGPFLVSAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRG 830
+ GP +V P ST+ NW EF+ W P + V +GDK+ RA +F + +
Sbjct: 225 YRNIPGPHMVLVPKSTLHNWMSEFKRWVPTLRSVCLIGDKEQRA-------AFVRDVLLP 277
Query: 831 GKKASRMKKEASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLN 890
G+ + V +TSYE++ + ++ +W L++DEAHR+KN +SK ++
Sbjct: 278 GE------------WDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVR 325
Query: 891 GYSLQHKLLLTGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFAD---IAKEDQIKKLH 947
+ ++LLLTGTPLQNNL EL+ LLNFL P+ F++ + F F + + +++LH
Sbjct: 326 EFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQKLVERLH 385
Query: 948 DMLGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGGNQVS 1007
+L P +LRR+KADV K++P K E+ + V LS MQ+++Y IL ++ + LN+ G +++
Sbjct: 386 MVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAGKMDKMR 445
Query: 1008 LLNVVMDLKKCCNHPYLFPVAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKNLKEGGH 1067
LLN++M L+KCCNHPYLF A P M+ L+ SGK+++L K+L LKE G
Sbjct: 446 LLNILMQLRKCCNHPYLFD-GAEPGPPYTTDMH----LVTNSGKMVVLDKLLPKLKEQGS 500
Query: 1068 RVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFCFLLSTR 1127
RVLIFSQMT++LD+LED+ Y+Y R+DG + RQ++I+ +N P + +F F+LSTR
Sbjct: 501 RVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTR 560
Query: 1128 AGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQV 1187
AGGLGINLATAD VI+YDSDWNP D+QA RAHRIGQ K V ++RF+T +VEERI +
Sbjct: 561 AGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVER 620
Query: 1188 AKKKMMLTHLVVRPG--LGSKTGSMSKQELDDILKFGTEELFKDEATDGGGDNKEGEDSS 1245
A+ K+ L +V++ G + + K E+ +++ G +F +KE E
Sbjct: 621 AEMKLRLDSIVIQQGRLVDQNLNKIGKDEMLQMIRHGATHVFA---------SKESE--- 668
Query: 1246 VIHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEEEV------- 1298
D+ I+ +L+R +T + MNE LS K+ + +R M E V
Sbjct: 669 ---ITDEDIDGILERGAKKTAE-----MNEKLS--KMGESSLRNFTMDTESSVYNFEGED 718
Query: 1299 --EREIIKQEESVDPDYWEKLLRHHYEQQQEDLAR----NLGKGKRIRKQVNYND 1347
E++ I E ++P E+ + + + R K R KQ N D
Sbjct: 719 YREKQKIAFTEWIEPPKRERKANYAVDAYFREALRVSEPKAPKAPRPPKQPNVQD 773
>gi|148612870 chromodomain helicase DNA binding protein 1-like [Homo
sapiens]
Length = 897
Score = 408 bits (1049), Expect = e-113
Identities = 229/519 (44%), Positives = 324/519 (62%), Gaps = 37/519 (7%)
Query: 722 TGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLVS 781
TG L YQ+EG+NWL + IL DEMGLGKT QT L + +GPFL+
Sbjct: 42 TGIHLRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLIL 101
Query: 782 APLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASRMKKEA 841
PLS + NW+ E + +AP + VTY GDK+ RA ++++ +K+E+
Sbjct: 102 CPLSVLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQD-----------------LKQES 144
Query: 842 SVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNGYSLQHKLLLT 901
+FHVLLT+YE+ D + L S W+ L+VDEAHRLKN S + L+ +S+ LLLT
Sbjct: 145 --RFHVLLTTYEICLKDASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLT 202
Query: 902 GTPLQNNLEELFHLLNFLTPERFHNLE--GFLEEFADIAKEDQ-IKKLHDMLGPHMLRRL 958
GTP+QN+L+EL+ LL+F+ P+ F E F++ + DI KE + +LH +L P +LRR+
Sbjct: 203 GTPIQNSLQELYSLLSFVEPDLFSKEEVGDFIQRYQDIEKESESASELHKLLQPFLLRRV 262
Query: 959 KADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGGNQVSLLNVVMDLKKC 1018
KA+V +P KTE+++ +S +QKKYYK IL ++ +A +V L N++ L+KC
Sbjct: 263 KAEVATELPKKTEVVIYHGMSALQKKYYKAILMKDLDAFENETA-KKVKLQNILSQLRKC 321
Query: 1019 CNHPYLFPVAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKNLKEGGHRVLIFSQMTKM 1078
+HPYLF E ++ G L ASGKL LL K+L L GGHRVL+FSQMT+M
Sbjct: 322 VDHPYLFDGVEPEPFEV------GDHLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQM 375
Query: 1079 LDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQ-FCFLLSTRAGGLGINLAT 1137
LD+L+D++++ GY YER+DG + G R AI F G Q F FLLSTRAGG+G+NL
Sbjct: 376 LDILQDYMDYRGYSYERVDGSVRGEERHLAIKNF---GQQPIFVFLLSTRAGGVGMNLTA 432
Query: 1138 ADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKKKMMLTHL 1197
ADTVI DSD+NP ND+QA +RAHRIGQNK V + R + R +VEE + + A K+ LT++
Sbjct: 433 ADTVIFVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNM 492
Query: 1198 VVRPG---LGS-KTGSMSKQELDDILKFGTEELFKDEAT 1232
++ G LG+ K + + +L +ILKFG ++L E +
Sbjct: 493 IIEGGHFTLGAQKPAADADLQLSEILKFGLDKLLASEGS 531
>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform F [Homo sapiens]
Length = 1613
Score = 394 bits (1012), Expect = e-109
Identities = 297/970 (30%), Positives = 457/970 (47%), Gaps = 140/970 (14%)
Query: 724 GTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLVSAP 783
G L YQ++GL WL + + ILADEMGLGKT+QT + L + GPFL+ P
Sbjct: 752 GVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVP 811
Query: 784 LSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASRMKKEASV 843
LST+ NW EF+ WAP + V+Y G +R +R GK
Sbjct: 812 LSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQ--------LRSGK----------- 852
Query: 844 KFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNG-YSLQHKLLLTG 902
F+VLLT+YE I D IL I W +IVDE HR+KN+ K +VLN Y +LLLTG
Sbjct: 853 -FNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTG 911
Query: 903 TPLQNNLEELFHLLNFLTPERFHNLEGFLEEF----------ADIAKEDQI---KKLHDM 949
TPLQN L EL+ LLNFL P F + F + F D+ +E+ I ++LH +
Sbjct: 912 TPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKV 971
Query: 950 LGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKY-----ILTRNFEALNARGGGN 1004
L P +LRRLK +V +P K E +++ ++S +Q+ Y++ +L + + +G G
Sbjct: 972 LRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGG 1031
Query: 1005 QVSLLNVVMDLKKCCNHPYLFP---VAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKN 1061
+L+N +M L+K CNHPY+F + E G+ G L RASGK LL ++L
Sbjct: 1032 TKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPK 1091
Query: 1062 LKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFC 1121
L+ H+VL+F QMT ++ ++ED+ + G+KY R+DG R + FN PG++ F
Sbjct: 1092 LRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFI 1151
Query: 1122 FLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVE 1181
FLLSTRAGGLG+NL +ADTVII+DSDWNPH D+QA RAHRIGQ +V + R T SVE
Sbjct: 1152 FLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVE 1211
Query: 1182 ERITQVAKKKMMLTHLVVRPGLGSKTGSMSKQE--LDDILKFGTEELFKDEATDGGGDNK 1239
E+I AK K+ + V++ G+ + S ++ L IL+ ++ +DE
Sbjct: 1212 EKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDEEEDEVP------- 1264
Query: 1240 EGEDSSVIHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEEEVE 1299
DD+ + +++ R+++E + ++ A+ R+ + EE+E+
Sbjct: 1265 ----------DDETVNQMIARHEEEFDLFMRMDLDRRREE---ARNPKRKPRLMEEDELP 1311
Query: 1300 REIIKQEESVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYNDGSQEDRDWQDDQ 1359
IIK + V+ R E+++E + G+G R RK+V+Y+D S ++ W
Sbjct: 1312 SWIIKDDAEVE--------RLTCEEEEEKM---FGRGSRHRKEVDYSD-SLTEKQWLK-- 1357
Query: 1360 SDNQSDYSVASEEGDEDFDERSEAPRRPSRKGLRNDKDKPLPPLLARVGGNIEVLGFNAR 1419
A EEG + E ++ SRK R D D G + +R
Sbjct: 1358 ---------AIEEGTLEEIEEEVRQKKSSRKRKR-DSD---------AGSSTPTTSTRSR 1398
Query: 1420 QRKAFLNAIMRYGMPPQDAFTTQWLVRDLRGKSEKEFKAYVSLFMRHLCEPGADGAETFA 1479
+ + G PP + + K+ K V +++ G +E F
Sbjct: 1399 DKDDESKKQKKRGRPPAEKLSPN------PPNLTKKMKKIVDAVIKYKDSSGRQLSEVFI 1452
Query: 1480 DGVPREGLSRQHVLTRIGVMSLIRKKVQEFEHVNGRWSMPELAEVEENKKMSQPGSPSPK 1539
R+ L + LIRK V +F+ + R + + + +K + +
Sbjct: 1453 QLPSRKELPEYY--------ELIRKPV-DFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQ 1503
Query: 1540 TPTPSTPGDTQPNTPAPVPPAEDGIKIEENSLKEEESIEGEKEVKSTAPETAIECTQAPA 1599
T E SL E+SI + S + E
Sbjct: 1504 TFN------------------------LEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGE 1539
Query: 1600 PASEDEKVVVEPPEGEEKVEKAEVKERTEEPMETEPKGAADVEKVEEKSAIDLTPIVVED 1659
+ E+E+ E E E + K ++K +E + KG + P+V +D
Sbjct: 1540 ESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGG----RRRPSRGSRAKPVVSDD 1595
Query: 1660 KEEKKEEEEK 1669
E+++EE++
Sbjct: 1596 DSEEEQEEDR 1605
Score = 33.9 bits (76), Expect = 1.6
Identities = 30/127 (23%), Positives = 58/127 (45%), Gaps = 5/127 (3%)
Query: 98 EVALRSDSEGSDYTPGKKKKKKLGPKKEKKSKSKRKEEEEEEDDDDDSKEPKSSAQLLED 157
EVA RSDSE S ++++++ P+ + +E+++ D D D + ++E+
Sbjct: 650 EVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIEN 709
Query: 158 WGMEDIDHVF--SEEDYRTLTNYKAFSQFVRPLIAAKNPKI--AVSKMMMVLGAKWREFS 213
+D+D + S+ R L +Y A + V + ++ + V K + G +W
Sbjct: 710 -AKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSL 768
Query: 214 TNNPFKG 220
NN G
Sbjct: 769 YNNNLNG 775
>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform D [Homo sapiens]
Length = 1616
Score = 394 bits (1012), Expect = e-109
Identities = 297/970 (30%), Positives = 457/970 (47%), Gaps = 137/970 (14%)
Query: 724 GTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLVSAP 783
G L YQ++GL WL + + ILADEMGLGKT+QT + L + GPFL+ P
Sbjct: 752 GVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVP 811
Query: 784 LSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASRMKKEASV 843
LST+ NW EF+ WAP + V+Y G +R +R GK
Sbjct: 812 LSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQ--------LRSGK----------- 852
Query: 844 KFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNG-YSLQHKLLLTG 902
F+VLLT+YE I D IL I W +IVDE HR+KN+ K +VLN Y +LLLTG
Sbjct: 853 -FNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTG 911
Query: 903 TPLQNNLEELFHLLNFLTPERFHNLEGFLEEF----------ADIAKEDQI---KKLHDM 949
TPLQN L EL+ LLNFL P F + F + F D+ +E+ I ++LH +
Sbjct: 912 TPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKV 971
Query: 950 LGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKY-----ILTRNFEALNARGGGN 1004
L P +LRRLK +V +P K E +++ ++S +Q+ Y++ +L + + +G G
Sbjct: 972 LRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGG 1031
Query: 1005 QVSLLNVVMDLKKCCNHPYLFP---VAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKN 1061
+L+N +M L+K CNHPY+F + E G+ G L RASGK LL ++L
Sbjct: 1032 TKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPK 1091
Query: 1062 LKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFC 1121
L+ H+VL+F QMT ++ ++ED+ + G+KY R+DG R + FN PG++ F
Sbjct: 1092 LRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFI 1151
Query: 1122 FLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVE 1181
FLLSTRAGGLG+NL +ADTVII+DSDWNPH D+QA RAHRIGQ +V + R T SVE
Sbjct: 1152 FLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVE 1211
Query: 1182 ERITQVAKKKMMLTHLVVRPGLGSKTGSMSKQE--LDDILKFGTEELFKDEATDGGGDNK 1239
E+I AK K+ + V++ G+ + S ++ L IL+ ++ +DE
Sbjct: 1212 EKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDEEEDEVP------- 1264
Query: 1240 EGEDSSVIHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEEEVE 1299
DD+ + +++ R+++E + ++ A+ R+ + EE+E+
Sbjct: 1265 ----------DDETVNQMIARHEEEFDLFMRMDLDRRREE---ARNPKRKPRLMEEDELP 1311
Query: 1300 REIIKQEESVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYNDGSQEDRDWQDDQ 1359
IIK + V+ R E+++E + G+G R RK+V+Y+D S ++ W
Sbjct: 1312 SWIIKDDAEVE--------RLTCEEEEEKM---FGRGSRHRKEVDYSD-SLTEKQWLKTL 1359
Query: 1360 SDNQSDYSVASEEGDEDFDERSEAPRRPSRKGLRNDKDKPLPPLLARVGGNIEVLGFNAR 1419
A EEG + E ++ SRK R D D G + +R
Sbjct: 1360 K--------AIEEGTLEEIEEEVRQKKSSRKRKR-DSD---------AGSSTPTTSTRSR 1401
Query: 1420 QRKAFLNAIMRYGMPPQDAFTTQWLVRDLRGKSEKEFKAYVSLFMRHLCEPGADGAETFA 1479
+ + G PP + + K+ K V +++ G +E F
Sbjct: 1402 DKDDESKKQKKRGRPPAEKLSPN------PPNLTKKMKKIVDAVIKYKDSSGRQLSEVFI 1455
Query: 1480 DGVPREGLSRQHVLTRIGVMSLIRKKVQEFEHVNGRWSMPELAEVEENKKMSQPGSPSPK 1539
R+ L + LIRK V +F+ + R + + + +K + +
Sbjct: 1456 QLPSRKELPEYY--------ELIRKPV-DFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQ 1506
Query: 1540 TPTPSTPGDTQPNTPAPVPPAEDGIKIEENSLKEEESIEGEKEVKSTAPETAIECTQAPA 1599
T E SL E+SI + S + E
Sbjct: 1507 TFN------------------------LEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGE 1542
Query: 1600 PASEDEKVVVEPPEGEEKVEKAEVKERTEEPMETEPKGAADVEKVEEKSAIDLTPIVVED 1659
+ E+E+ E E E + K ++K +E + KG + P+V +D
Sbjct: 1543 ESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGG----RRRPSRGSRAKPVVSDD 1598
Query: 1660 KEEKKEEEEK 1669
E+++EE++
Sbjct: 1599 DSEEEQEEDR 1608
Score = 33.9 bits (76), Expect = 1.6
Identities = 30/127 (23%), Positives = 58/127 (45%), Gaps = 5/127 (3%)
Query: 98 EVALRSDSEGSDYTPGKKKKKKLGPKKEKKSKSKRKEEEEEEDDDDDSKEPKSSAQLLED 157
EVA RSDSE S ++++++ P+ + +E+++ D D D + ++E+
Sbjct: 650 EVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIEN 709
Query: 158 WGMEDIDHVF--SEEDYRTLTNYKAFSQFVRPLIAAKNPKI--AVSKMMMVLGAKWREFS 213
+D+D + S+ R L +Y A + V + ++ + V K + G +W
Sbjct: 710 -AKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSL 768
Query: 214 TNNPFKG 220
NN G
Sbjct: 769 YNNNLNG 775
>gi|192807318 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform E [Homo sapiens]
Length = 1614
Score = 392 bits (1008), Expect = e-108
Identities = 248/706 (35%), Positives = 374/706 (52%), Gaps = 83/706 (11%)
Query: 724 GTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLVSAP 783
G L YQ++GL WL + + ILADEMGLGKT+QT + L + GPFL+ P
Sbjct: 752 GVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVP 811
Query: 784 LSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASRMKKEASV 843
LST+ NW EF+ WAP + V+Y G +R +R GK
Sbjct: 812 LSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQ--------LRSGK----------- 852
Query: 844 KFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNG-YSLQHKLLLTG 902
F+VLLT+YE I D IL I W +IVDE HR+KN+ K +VLN Y +LLLTG
Sbjct: 853 -FNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTG 911
Query: 903 TPLQNNLEELFHLLNFLTPERFHNLEGFLEEF----------ADIAKEDQI---KKLHDM 949
TPLQN L EL+ LLNFL P F + F + F D+ +E+ I ++LH +
Sbjct: 912 TPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKV 971
Query: 950 LGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKY-----ILTRNFEALNARGGGN 1004
L P +LRRLK +V +P K E +++ ++S +Q+ Y++ +L + + +G G
Sbjct: 972 LRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGG 1031
Query: 1005 QVSLLNVVMDLKKCCNHPYLFP---VAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKN 1061
+L+N +M L+K CNHPY+F + E G+ G L RASGK LL ++L
Sbjct: 1032 TKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPK 1091
Query: 1062 LKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFC 1121
L+ H+VL+F QMT ++ ++ED+ + G+KY R+DG R + FN PG++ F
Sbjct: 1092 LRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFI 1151
Query: 1122 FLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVE 1181
FLLSTRAGGLG+NL +ADTVII+DSDWNPH D+QA RAHRIGQ +V + R T SVE
Sbjct: 1152 FLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVE 1211
Query: 1182 ERITQVAKKKMMLTHLVVRPGLGSKTGSMSKQE--LDDILKFGTEELFKDEATDGGGDNK 1239
E+I AK K+ + V++ G+ + S ++ L IL+ ++ +DE
Sbjct: 1212 EKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDEEEDEVP------- 1264
Query: 1240 EGEDSSVIHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEEEVE 1299
DD+ + +++ R+++E + ++ A+ R+ + EE+E+
Sbjct: 1265 ----------DDETVNQMIARHEEEFDLFMRMDLDRRREE---ARNPKRKPRLMEEDELP 1311
Query: 1300 REIIKQEESVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYNDGSQEDRDWQD-- 1357
IIK + V+ R E+++E + G+G R RK+V+Y+D S ++ W
Sbjct: 1312 SWIIKDDAEVE--------RLTCEEEEEKM---FGRGSRHRKEVDYSD-SLTEKQWLKAI 1359
Query: 1358 -----DQSDNQSDYSVASEEGDEDFDERSEAPRRPSRKGLRNDKDK 1398
++ + + +S + D D S P +R ++D+ K
Sbjct: 1360 EEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESK 1405
Score = 33.9 bits (76), Expect = 1.6
Identities = 30/127 (23%), Positives = 58/127 (45%), Gaps = 5/127 (3%)
Query: 98 EVALRSDSEGSDYTPGKKKKKKLGPKKEKKSKSKRKEEEEEEDDDDDSKEPKSSAQLLED 157
EVA RSDSE S ++++++ P+ + +E+++ D D D + ++E+
Sbjct: 650 EVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIEN 709
Query: 158 WGMEDIDHVF--SEEDYRTLTNYKAFSQFVRPLIAAKNPKI--AVSKMMMVLGAKWREFS 213
+D+D + S+ R L +Y A + V + ++ + V K + G +W
Sbjct: 710 -AKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSL 768
Query: 214 TNNPFKG 220
NN G
Sbjct: 769 YNNNLNG 775
>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform b [Homo sapiens]
Length = 1572
Score = 392 bits (1008), Expect = e-108
Identities = 304/975 (31%), Positives = 462/975 (47%), Gaps = 158/975 (16%)
Query: 724 GTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLVSAP 783
GTL YQ++GL W+ + + ILADEMGLGKT+QT + L + GP+L+ P
Sbjct: 722 GTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVP 781
Query: 784 LSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASRMKKEASV 843
LST+ NW EF+ WAP + ++Y G R S + + S
Sbjct: 782 LSTLSNWTYEFDKWAPSVVKISYKGTPAMRR--------------------SLVPQLRSG 821
Query: 844 KFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNG-YSLQHKLLLTG 902
KF+VLLT+YE I D IL I W +IVDE HR+KN+ K +VLN Y ++LLTG
Sbjct: 822 KFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTG 881
Query: 903 TPLQNNLEELFHLLNFLTPERFHNLEGFLEEF----------ADIAKEDQI---KKLHDM 949
TPLQN L EL+ LLNFL P F + F + F D+ +E+ I ++LH +
Sbjct: 882 TPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKV 941
Query: 950 LGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKY-----ILTRNFEALNARGGGN 1004
L P +LRRLK +V +P K E +++ ++S +QK Y++ IL + + +G G
Sbjct: 942 LRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGG 1001
Query: 1005 QVSLLNVVMDLKKCCNHPYLFP---VAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKN 1061
+L+N +M L+K CNHPY+F + E NG+ +G+ L RASGK LL ++L
Sbjct: 1002 AKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPK 1061
Query: 1062 LKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFC 1121
L+ HRVL+F QMT ++ ++ED+ + Y R+DG R + +FN PG+Q F
Sbjct: 1062 LRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFI 1121
Query: 1122 FLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVE 1181
FLLSTRAGGLG+NL ADTV+I+DSDWNPH D+QA RAHRIGQ +V + R T SVE
Sbjct: 1122 FLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVE 1181
Query: 1182 ERITQVAKKKMMLTHLVVRPGLGSKTGSMSKQE--LDDILKFGTEELFKDEATDGGGDNK 1239
E+I AK K+ + V++ G+ + S ++ L IL+ E +DE
Sbjct: 1182 EKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEENEEEDEVP------- 1234
Query: 1240 EGEDSSVIHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEEEVE 1299
DD+ + +++ R ++E + M+ A+ R+ + EE+E+
Sbjct: 1235 ----------DDETLNQMIARREEEFDLFMRMDMDRRRED---ARNPKRKPRLMEEDELP 1281
Query: 1300 REIIKQEESVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYNDGSQEDRDWQDDQ 1359
IIK + V+ R E+++E + G+G R R+ V+Y+D E + W
Sbjct: 1282 SWIIKDDAEVE--------RLTCEEEEEKI---FGRGSRQRRDVDYSDALTE-KQWLR-- 1327
Query: 1360 SDNQSDYSVASEEGDEDFDERSEAPRRPSRKGLRN-DKDKPLPPLLARVGGNIEVLGFNA 1418
A E+G + +E E R RK RN DKD
Sbjct: 1328 ---------AIEDG--NLEEMEEEVRLKKRKRRRNVDKDP-------------------- 1356
Query: 1419 RQRKAFLNAIMRYGMPPQDAFTTQWLVRDLRGKSEKEFKAYVSLFMRHLCEPGADGAETF 1478
++ A R G PP + + K K+ A + + + G +E F
Sbjct: 1357 -AKEDVEKAKKRRGRPPAEKLSPN------PPKLTKQMNAIIDTVINYKDSSGRQLSEVF 1409
Query: 1479 ADGVPREGLSRQHVLTRIGVMSLIRKKVQEFEHVNGRWSMPELAEVEENKKMSQPGSPSP 1538
R+ L + LIRK V +F+ + R + +K S
Sbjct: 1410 IQLPSRKELPEYY--------ELIRKPV-DFKKIKER--------IRNHKYRSL------ 1446
Query: 1539 KTPTPSTPGDTQPNTPAPVPPAEDGIKIEENSLKEEESIEGEKEVKSTAPETAIECTQAP 1598
GD + + A+ +E + + E+SI + KS + A E
Sbjct: 1447 --------GDLEKDVMLLCHNAQT-FNLEGSQI-YEDSIVLQSVFKSARQKIAKEEESED 1496
Query: 1599 APASEDEKVVVEPPEGEEKVEKAEVK-ERTEEPMETEPKGAADVEKVEEKSAIDLTPIVV 1657
E+E+ E E E K K ++K + ++ + KG + + K P+V
Sbjct: 1497 ESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNRGKAK------PVVS 1550
Query: 1658 E-DKEEKKEEEEKKE 1671
+ D +E+++E E+ E
Sbjct: 1551 DFDSDEEQDEREQSE 1565
Score = 38.5 bits (88), Expect = 0.064
Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 12/97 (12%)
Query: 54 KKKPKKPRDPKIPKSKRQKKERMLLCRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTPG 113
KK ++ R+ K +K+ MLLC + EG + E+ + L+S
Sbjct: 1432 KKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDS--IVLQSVF-------- 1481
Query: 114 KKKKKKLGPKKEKKSKSKRKEEEEEEDDDDDSKEPKS 150
K ++K+ KE++S+ + EEEEEED+++ E KS
Sbjct: 1482 KSARQKIA--KEEESEDESNEEEEEEDEEESESEAKS 1516
Score = 34.3 bits (77), Expect = 1.2
Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 4/98 (4%)
Query: 1278 SSFKVAQYVVREEEMGEEEEVEREIIKQEESVDPDYWEKLLRHHYEQQQEDLARNLGKGK 1337
S FK A+ + +EE E+E E E + EE + + ++ +++D R+ GKGK
Sbjct: 1479 SVFKSARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKL-NKKDDKGRDKGKGK 1537
Query: 1338 RIRKQVNYNDGSQEDRDWQDDQSDNQSDYSVASEEGDE 1375
K+ N D+ D+ ++ + S S DE
Sbjct: 1538 ---KRPNRGKAKPVVSDFDSDEEQDEREQSEGSGTDDE 1572
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 392 bits (1007), Expect = e-108
Identities = 253/699 (36%), Positives = 369/699 (52%), Gaps = 90/699 (12%)
Query: 724 GTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLVSAP 783
GTL YQ++GL W+ + + ILADEMGLGKT+QT + L + GP+L+ P
Sbjct: 722 GTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVP 781
Query: 784 LSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASRMKKEASV 843
LST+ NW EF+ WAP + ++Y G R S + + S
Sbjct: 782 LSTLSNWTYEFDKWAPSVVKISYKGTPAMRR--------------------SLVPQLRSG 821
Query: 844 KFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNG-YSLQHKLLLTG 902
KF+VLLT+YE I D IL I W +IVDE HR+KN+ K +VLN Y ++LLTG
Sbjct: 822 KFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTG 881
Query: 903 TPLQNNLEELFHLLNFLTPERFHNLEGFLEEF----------ADIAKEDQI---KKLHDM 949
TPLQN L EL+ LLNFL P F + F + F D+ +E+ I ++LH +
Sbjct: 882 TPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKV 941
Query: 950 LGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKY-----ILTRNFEALNARGGGN 1004
L P +LRRLK +V +P K E +++ ++S +QK Y++ IL + + +G G
Sbjct: 942 LRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGG 1001
Query: 1005 QVSLLNVVMDLKKCCNHPYLFP---VAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKN 1061
+L+N +M L+K CNHPY+F + E NG+ +G+ L RASGK LL ++L
Sbjct: 1002 AKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPK 1061
Query: 1062 LKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFC 1121
L+ HRVL+F QMT ++ ++ED+ + Y R+DG R + +FN PG+Q F
Sbjct: 1062 LRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFI 1121
Query: 1122 FLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVE 1181
FLLSTRAGGLG+NL ADTV+I+DSDWNPH D+QA RAHRIGQ +V + R T SVE
Sbjct: 1122 FLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVE 1181
Query: 1182 ERITQVAKKKMMLTHLVVRPGLGSKTGSMSKQE--LDDILKFGTEELFKDEATDGGGDNK 1239
E+I AK K+ + V++ G+ + S ++ L IL+ E +DE
Sbjct: 1182 EKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEENEEEDEVP------- 1234
Query: 1240 EGEDSSVIHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEEEVE 1299
DD+ + +++ R ++E + M+ A+ R+ + EE+E+
Sbjct: 1235 ----------DDETLNQMIARREEEFDLFMRMDMDRRRED---ARNPKRKPRLMEEDELP 1281
Query: 1300 REIIKQEESVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYNDGSQEDRDWQDDQ 1359
IIK + V+ R E+++E + G+G R R+ V+Y+D E + W
Sbjct: 1282 SWIIKDDAEVE--------RLTCEEEEEKI---FGRGSRQRRDVDYSDALTE-KQWLR-- 1327
Query: 1360 SDNQSDYSVASEEGDEDFDERSEAPRRPSRKGLRN-DKD 1397
A E+G + +E E R RK RN DKD
Sbjct: 1328 ---------AIEDG--NLEEMEEEVRLKKRKRRRNVDKD 1355
Score = 38.5 bits (88), Expect = 0.064
Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 12/97 (12%)
Query: 54 KKKPKKPRDPKIPKSKRQKKERMLLCRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTPG 113
KK ++ R+ K +K+ MLLC + EG + E+ + L+S
Sbjct: 1450 KKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDS--IVLQSVF-------- 1499
Query: 114 KKKKKKLGPKKEKKSKSKRKEEEEEEDDDDDSKEPKS 150
K ++K+ KE++S+ + EEEEEED+++ E KS
Sbjct: 1500 KSARQKIA--KEEESEDESNEEEEEEDEEESESEAKS 1534
Score = 34.3 bits (77), Expect = 1.2
Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 4/98 (4%)
Query: 1278 SSFKVAQYVVREEEMGEEEEVEREIIKQEESVDPDYWEKLLRHHYEQQQEDLARNLGKGK 1337
S FK A+ + +EE E+E E E + EE + + ++ +++D R+ GKGK
Sbjct: 1497 SVFKSARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKL-NKKDDKGRDKGKGK 1555
Query: 1338 RIRKQVNYNDGSQEDRDWQDDQSDNQSDYSVASEEGDE 1375
K+ N D+ D+ ++ + S S DE
Sbjct: 1556 ---KRPNRGKAKPVVSDFDSDEEQDEREQSEGSGTDDE 1590
Score = 31.6 bits (70), Expect = 7.8
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 7/128 (5%)
Query: 1343 VNYNDGSQEDRDWQDDQSDNQSDYSVASEEGD----EDFDERSEAPRRPSRKGLRNDKDK 1398
+ + + ++E+ + DD++ NQ + EE D D D R E R P RK ++D+
Sbjct: 1221 LEHEEENEEEDEVPDDETLNQM-IARREEEFDLFMRMDMDRRREDARNPKRKPRLMEEDE 1279
Query: 1399 PLPPLLARVGGNIEVLGFNARQRKAF-LNAIMRYGMPPQDAFTTQWLVRDLRGKSEKEFK 1457
LP + + +E L + K F + R + DA T + +R + + +E +
Sbjct: 1280 -LPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEME 1338
Query: 1458 AYVSLFMR 1465
V L R
Sbjct: 1339 EEVRLKKR 1346
>gi|192807314 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform C [Homo sapiens]
Length = 1617
Score = 391 bits (1005), Expect = e-108
Identities = 248/709 (34%), Positives = 374/709 (52%), Gaps = 86/709 (12%)
Query: 724 GTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLVSAP 783
G L YQ++GL WL + + ILADEMGLGKT+QT + L + GPFL+ P
Sbjct: 752 GVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVP 811
Query: 784 LSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASRMKKEASV 843
LST+ NW EF+ WAP + V+Y G +R +R GK
Sbjct: 812 LSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQ--------LRSGK----------- 852
Query: 844 KFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNG-YSLQHKLLLTG 902
F+VLLT+YE I D IL I W +IVDE HR+KN+ K +VLN Y +LLLTG
Sbjct: 853 -FNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTG 911
Query: 903 TPLQNNLEELFHLLNFLTPERFHNLEGFLEEF----------ADIAKEDQI---KKLHDM 949
TPLQN L EL+ LLNFL P F + F + F D+ +E+ I ++LH +
Sbjct: 912 TPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKV 971
Query: 950 LGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKY-----ILTRNFEALNARGGGN 1004
L P +LRRLK +V +P K E +++ ++S +Q+ Y++ +L + + +G G
Sbjct: 972 LRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGG 1031
Query: 1005 QVSLLNVVMDLKKCCNHPYLFP---VAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKN 1061
+L+N +M L+K CNHPY+F + E G+ G L RASGK LL ++L
Sbjct: 1032 TKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPK 1091
Query: 1062 LKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFC 1121
L+ H+VL+F QMT ++ ++ED+ + G+KY R+DG R + FN PG++ F
Sbjct: 1092 LRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFI 1151
Query: 1122 FLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVE 1181
FLLSTRAGGLG+NL +ADTVII+DSDWNPH D+QA RAHRIGQ +V + R T SVE
Sbjct: 1152 FLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVE 1211
Query: 1182 ERITQVAKKKMMLTHLVVRPGLGSKTGSMSKQE--LDDILKFGTEELFKDEATDGGGDNK 1239
E+I AK K+ + V++ G+ + S ++ L IL+ ++ +DE
Sbjct: 1212 EKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDEEEDEVP------- 1264
Query: 1240 EGEDSSVIHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEEEVE 1299
DD+ + +++ R+++E + ++ A+ R+ + EE+E+
Sbjct: 1265 ----------DDETVNQMIARHEEEFDLFMRMDLDRRREE---ARNPKRKPRLMEEDELP 1311
Query: 1300 REIIKQEESVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYNDGSQEDRDWQD-- 1357
IIK + V+ R E+++E + G+G R RK+V+Y+D S ++ W
Sbjct: 1312 SWIIKDDAEVE--------RLTCEEEEEKM---FGRGSRHRKEVDYSD-SLTEKQWLKTL 1359
Query: 1358 --------DQSDNQSDYSVASEEGDEDFDERSEAPRRPSRKGLRNDKDK 1398
++ + + +S + D D S P +R ++D+ K
Sbjct: 1360 KAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESK 1408
Score = 33.9 bits (76), Expect = 1.6
Identities = 30/127 (23%), Positives = 58/127 (45%), Gaps = 5/127 (3%)
Query: 98 EVALRSDSEGSDYTPGKKKKKKLGPKKEKKSKSKRKEEEEEEDDDDDSKEPKSSAQLLED 157
EVA RSDSE S ++++++ P+ + +E+++ D D D + ++E+
Sbjct: 650 EVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIEN 709
Query: 158 WGMEDIDHVF--SEEDYRTLTNYKAFSQFVRPLIAAKNPKI--AVSKMMMVLGAKWREFS 213
+D+D + S+ R L +Y A + V + ++ + V K + G +W
Sbjct: 710 -AKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSL 768
Query: 214 TNNPFKG 220
NN G
Sbjct: 769 YNNNLNG 775
>gi|192807312 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform B [Homo sapiens]
Length = 1647
Score = 390 bits (1003), Expect = e-108
Identities = 251/722 (34%), Positives = 381/722 (52%), Gaps = 82/722 (11%)
Query: 724 GTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLVSAP 783
G L YQ++GL WL + + ILADEMGLGKT+QT + L + GPFL+ P
Sbjct: 752 GVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVP 811
Query: 784 LSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASRMKKEASV 843
LST+ NW EF+ WAP + V+Y G +R +R GK
Sbjct: 812 LSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQ--------LRSGK----------- 852
Query: 844 KFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNG-YSLQHKLLLTG 902
F+VLLT+YE I D IL I W +IVDE HR+KN+ K +VLN Y +LLLTG
Sbjct: 853 -FNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTG 911
Query: 903 TPLQNNLEELFHLLNFLTPERFHNLEGFLEEF----------ADIAKEDQI---KKLHDM 949
TPLQN L EL+ LLNFL P F + F + F D+ +E+ I ++LH +
Sbjct: 912 TPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKV 971
Query: 950 LGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKY-----ILTRNFEALNARGGGN 1004
L P +LRRLK +V +P K E +++ ++S +Q+ Y++ +L + + +G G
Sbjct: 972 LRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGG 1031
Query: 1005 QVSLLNVVMDLKKCCNHPYLFP---VAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKN 1061
+L+N +M L+K CNHPY+F + E G+ G L RASGK LL ++L
Sbjct: 1032 TKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPK 1091
Query: 1062 LKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFC 1121
L+ H+VL+F QMT ++ ++ED+ + G+KY R+DG R + FN PG++ F
Sbjct: 1092 LRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFI 1151
Query: 1122 FLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVE 1181
FLLSTRAGGLG+NL +ADTVII+DSDWNPH D+QA RAHRIGQ +V + R T SVE
Sbjct: 1152 FLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVE 1211
Query: 1182 ERITQVAKKKMMLTHLVVRPGLGSKTGSMSKQE--LDDILKFGTEELFKDEATDGG---- 1235
E+I AK K+ + V++ G+ + S ++ L IL+ ++ + +T G
Sbjct: 1212 EKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESRHCSTGSGSASF 1271
Query: 1236 --------GDNKEGEDSSVIHY----DDKAIERLLDRNQDETEDTELQGMNEYLSSFKVA 1283
G N + E+ + DD+ + +++ R+++E + ++ A
Sbjct: 1272 AHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREE---A 1328
Query: 1284 QYVVREEEMGEEEEVEREIIKQEESVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQV 1343
+ R+ + EE+E+ IIK + V+ R E+++E + G+G R RK+V
Sbjct: 1329 RNPKRKPRLMEEDELPSWIIKDDAEVE--------RLTCEEEEEKM---FGRGSRHRKEV 1377
Query: 1344 NYNDGSQEDRDWQD-------DQSDNQSDYSVASEEGDEDFDERSEAPRRPSRKGLRNDK 1396
+Y+D S ++ W ++ + + +S + D D S P +R ++D+
Sbjct: 1378 DYSD-SLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDE 1436
Query: 1397 DK 1398
K
Sbjct: 1437 SK 1438
Score = 33.9 bits (76), Expect = 1.6
Identities = 30/127 (23%), Positives = 58/127 (45%), Gaps = 5/127 (3%)
Query: 98 EVALRSDSEGSDYTPGKKKKKKLGPKKEKKSKSKRKEEEEEEDDDDDSKEPKSSAQLLED 157
EVA RSDSE S ++++++ P+ + +E+++ D D D + ++E+
Sbjct: 650 EVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIEN 709
Query: 158 WGMEDIDHVF--SEEDYRTLTNYKAFSQFVRPLIAAKNPKI--AVSKMMMVLGAKWREFS 213
+D+D + S+ R L +Y A + V + ++ + V K + G +W
Sbjct: 710 -AKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSL 768
Query: 214 TNNPFKG 220
NN G
Sbjct: 769 YNNNLNG 775
>gi|21071056 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform B [Homo sapiens]
Length = 1647
Score = 390 bits (1003), Expect = e-108
Identities = 251/722 (34%), Positives = 381/722 (52%), Gaps = 82/722 (11%)
Query: 724 GTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLVSAP 783
G L YQ++GL WL + + ILADEMGLGKT+QT + L + GPFL+ P
Sbjct: 752 GVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVP 811
Query: 784 LSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASRMKKEASV 843
LST+ NW EF+ WAP + V+Y G +R +R GK
Sbjct: 812 LSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQ--------LRSGK----------- 852
Query: 844 KFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNG-YSLQHKLLLTG 902
F+VLLT+YE I D IL I W +IVDE HR+KN+ K +VLN Y +LLLTG
Sbjct: 853 -FNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTG 911
Query: 903 TPLQNNLEELFHLLNFLTPERFHNLEGFLEEF----------ADIAKEDQI---KKLHDM 949
TPLQN L EL+ LLNFL P F + F + F D+ +E+ I ++LH +
Sbjct: 912 TPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKV 971
Query: 950 LGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKY-----ILTRNFEALNARGGGN 1004
L P +LRRLK +V +P K E +++ ++S +Q+ Y++ +L + + +G G
Sbjct: 972 LRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGG 1031
Query: 1005 QVSLLNVVMDLKKCCNHPYLFP---VAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKN 1061
+L+N +M L+K CNHPY+F + E G+ G L RASGK LL ++L
Sbjct: 1032 TKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPK 1091
Query: 1062 LKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFC 1121
L+ H+VL+F QMT ++ ++ED+ + G+KY R+DG R + FN PG++ F
Sbjct: 1092 LRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFI 1151
Query: 1122 FLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVE 1181
FLLSTRAGGLG+NL +ADTVII+DSDWNPH D+QA RAHRIGQ +V + R T SVE
Sbjct: 1152 FLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVE 1211
Query: 1182 ERITQVAKKKMMLTHLVVRPGLGSKTGSMSKQE--LDDILKFGTEELFKDEATDGG---- 1235
E+I AK K+ + V++ G+ + S ++ L IL+ ++ + +T G
Sbjct: 1212 EKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESRHCSTGSGSASF 1271
Query: 1236 --------GDNKEGEDSSVIHY----DDKAIERLLDRNQDETEDTELQGMNEYLSSFKVA 1283
G N + E+ + DD+ + +++ R+++E + ++ A
Sbjct: 1272 AHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREE---A 1328
Query: 1284 QYVVREEEMGEEEEVEREIIKQEESVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQV 1343
+ R+ + EE+E+ IIK + V+ R E+++E + G+G R RK+V
Sbjct: 1329 RNPKRKPRLMEEDELPSWIIKDDAEVE--------RLTCEEEEEKM---FGRGSRHRKEV 1377
Query: 1344 NYNDGSQEDRDWQD-------DQSDNQSDYSVASEEGDEDFDERSEAPRRPSRKGLRNDK 1396
+Y+D S ++ W ++ + + +S + D D S P +R ++D+
Sbjct: 1378 DYSD-SLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDE 1436
Query: 1397 DK 1398
K
Sbjct: 1437 SK 1438
Score = 33.9 bits (76), Expect = 1.6
Identities = 30/127 (23%), Positives = 58/127 (45%), Gaps = 5/127 (3%)
Query: 98 EVALRSDSEGSDYTPGKKKKKKLGPKKEKKSKSKRKEEEEEEDDDDDSKEPKSSAQLLED 157
EVA RSDSE S ++++++ P+ + +E+++ D D D + ++E+
Sbjct: 650 EVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIEN 709
Query: 158 WGMEDIDHVF--SEEDYRTLTNYKAFSQFVRPLIAAKNPKI--AVSKMMMVLGAKWREFS 213
+D+D + S+ R L +Y A + V + ++ + V K + G +W
Sbjct: 710 -AKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSL 768
Query: 214 TNNPFKG 220
NN G
Sbjct: 769 YNNNLNG 775
>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform A [Homo sapiens]
Length = 1679
Score = 386 bits (992), Expect = e-106
Identities = 243/672 (36%), Positives = 363/672 (54%), Gaps = 75/672 (11%)
Query: 724 GTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLVSAP 783
G L YQ++GL WL + + ILADEMGLGKT+QT + L + GPFL+ P
Sbjct: 752 GVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVP 811
Query: 784 LSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASRMKKEASV 843
LST+ NW EF+ WAP + V+Y G +R +R GK
Sbjct: 812 LSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQ--------LRSGK----------- 852
Query: 844 KFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNG-YSLQHKLLLTG 902
F+VLLT+YE I D IL I W +IVDE HR+KN+ K +VLN Y +LLLTG
Sbjct: 853 -FNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTG 911
Query: 903 TPLQNNLEELFHLLNFLTPERFHNLEGFLEEF----------ADIAKEDQI---KKLHDM 949
TPLQN L EL+ LLNFL P F + F + F D+ +E+ I ++LH +
Sbjct: 912 TPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKV 971
Query: 950 LGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKY-----ILTRNFEALNARGGGN 1004
L P +LRRLK +V +P K E +++ ++S +Q+ Y++ +L + + +G G
Sbjct: 972 LRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGG 1031
Query: 1005 QVSLLNVVMDLKKCCNHPYLFP---VAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKN 1061
+L+N +M L+K CNHPY+F + E G+ G L RASGK LL ++L
Sbjct: 1032 TKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPK 1091
Query: 1062 LKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFC 1121
L+ H+VL+F QMT ++ ++ED+ + G+KY R+DG R + FN PG++ F
Sbjct: 1092 LRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFI 1151
Query: 1122 FLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVE 1181
FLLSTRAGGLG+NL +ADTVII+DSDWNPH D+QA RAHRIGQ +V + R T SVE
Sbjct: 1152 FLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVE 1211
Query: 1182 ERITQVAKKKMMLTHLVVRPGLGSKTGSMSKQE--LDDILKFGTEELFKDEATDGG---- 1235
E+I AK K+ + V++ G+ + S ++ L IL+ ++ + +T G
Sbjct: 1212 EKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESRHCSTGSGSASF 1271
Query: 1236 --------GDNKEGEDSSVIHY----DDKAIERLLDRNQDETEDTELQGMNEYLSSFKVA 1283
G N + E+ + DD+ + +++ R+++E + ++ A
Sbjct: 1272 AHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREE---A 1328
Query: 1284 QYVVREEEMGEEEEVEREIIKQEESVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQV 1343
+ R+ + EE+E+ IIK + V+ R E+++E + G+G R RK+V
Sbjct: 1329 RNPKRKPRLMEEDELPSWIIKDDAEVE--------RLTCEEEEEKM---FGRGSRHRKEV 1377
Query: 1344 NYNDGSQEDRDW 1355
+Y+D S ++ W
Sbjct: 1378 DYSD-SLTEKQW 1388
Score = 33.9 bits (76), Expect = 1.6
Identities = 30/127 (23%), Positives = 58/127 (45%), Gaps = 5/127 (3%)
Query: 98 EVALRSDSEGSDYTPGKKKKKKLGPKKEKKSKSKRKEEEEEEDDDDDSKEPKSSAQLLED 157
EVA RSDSE S ++++++ P+ + +E+++ D D D + ++E+
Sbjct: 650 EVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIEN 709
Query: 158 WGMEDIDHVF--SEEDYRTLTNYKAFSQFVRPLIAAKNPKI--AVSKMMMVLGAKWREFS 213
+D+D + S+ R L +Y A + V + ++ + V K + G +W
Sbjct: 710 -AKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSL 768
Query: 214 TNNPFKG 220
NN G
Sbjct: 769 YNNNLNG 775
>gi|190358536 SWI/SNF-related, matrix-associated actin-dependent
regulator of chromatin, subfamily a, containing DEAD/H
box 1 isoform a [Homo sapiens]
Length = 1028
Score = 274 bits (701), Expect = 5e-73
Identities = 180/525 (34%), Positives = 266/525 (50%), Gaps = 76/525 (14%)
Query: 725 TLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLVSAPL 784
+L PYQ GLNWL G + ILADEMGLGKT+Q FL LY+EG++ GP L+ P
Sbjct: 496 SLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLYQEGNN-GPHLIVVPA 554
Query: 785 STIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFS-FEDNAIRGGKKASRMKKEASV 843
STI NW RE +W P + V+ Y G ++ R IR N S +ED
Sbjct: 555 STIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYED------------------ 596
Query: 844 KFHVLLTSYELI---TIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNGYSLQHKLLL 900
++V++T+Y + D ++ + I DE H LKN S ++ L + ++LLL
Sbjct: 597 -YNVIVTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLL 655
Query: 901 TGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEF----------ADIAKEDQIKKLHDML 950
TGTP+QNNL EL LLNF+ P F + + I ++++I ++
Sbjct: 656 TGTPVQNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQII 715
Query: 951 GPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGGNQVSLLN 1010
P +LRR+K +V K +P K + I +S Q++ Y + R +++N + N
Sbjct: 716 KPFILRRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCN 775
Query: 1011 VVMDLKKCCNHPYLF-------------------PVAAMEAPKM---------------- 1035
V+M L+K NHP L P P +
Sbjct: 776 VMMQLRKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVL 835
Query: 1036 ------PNGMYDGSALIRASGKLLLLQKMLKNLKEGGHRVLIFSQMTKMLDLLEDFLEHE 1089
N LI SGK +L +L LK+ G RV++FSQ T MLD+LE L+H
Sbjct: 836 CKQYRHINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHH 895
Query: 1090 GYKYERIDGGITGNMRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIYDSDWN 1149
++Y R+DG + R ID FN F FLLST+AGGLGINL +A+ VI++D D N
Sbjct: 896 QHRYLRLDGKTQISERIHLIDEFNT-DMDIFVFLLSTKAGGLGINLTSANVVILHDIDCN 954
Query: 1150 PHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKKKMML 1194
P+ND QA R HR+GQ K+V++ + +++ ++EE + ++ ++K+ L
Sbjct: 955 PYNDKQAEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKL 999
>gi|190358532 SWI/SNF-related, matrix-associated actin-dependent
regulator of chromatin, subfamily a, containing DEAD/H
box 1 isoform a [Homo sapiens]
Length = 1028
Score = 274 bits (701), Expect = 5e-73
Identities = 180/525 (34%), Positives = 266/525 (50%), Gaps = 76/525 (14%)
Query: 725 TLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLVSAPL 784
+L PYQ GLNWL G + ILADEMGLGKT+Q FL LY+EG++ GP L+ P
Sbjct: 496 SLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLYQEGNN-GPHLIVVPA 554
Query: 785 STIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFS-FEDNAIRGGKKASRMKKEASV 843
STI NW RE +W P + V+ Y G ++ R IR N S +ED
Sbjct: 555 STIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYED------------------ 596
Query: 844 KFHVLLTSYELI---TIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNGYSLQHKLLL 900
++V++T+Y + D ++ + I DE H LKN S ++ L + ++LLL
Sbjct: 597 -YNVIVTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLL 655
Query: 901 TGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEF----------ADIAKEDQIKKLHDML 950
TGTP+QNNL EL LLNF+ P F + + I ++++I ++
Sbjct: 656 TGTPVQNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQII 715
Query: 951 GPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGGNQVSLLN 1010
P +LRR+K +V K +P K + I +S Q++ Y + R +++N + N
Sbjct: 716 KPFILRRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCN 775
Query: 1011 VVMDLKKCCNHPYLF-------------------PVAAMEAPKM---------------- 1035
V+M L+K NHP L P P +
Sbjct: 776 VMMQLRKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVL 835
Query: 1036 ------PNGMYDGSALIRASGKLLLLQKMLKNLKEGGHRVLIFSQMTKMLDLLEDFLEHE 1089
N LI SGK +L +L LK+ G RV++FSQ T MLD+LE L+H
Sbjct: 836 CKQYRHINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHH 895
Query: 1090 GYKYERIDGGITGNMRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIYDSDWN 1149
++Y R+DG + R ID FN F FLLST+AGGLGINL +A+ VI++D D N
Sbjct: 896 QHRYLRLDGKTQISERIHLIDEFNT-DMDIFVFLLSTKAGGLGINLTSANVVILHDIDCN 954
Query: 1150 PHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKKKMML 1194
P+ND QA R HR+GQ K+V++ + +++ ++EE + ++ ++K+ L
Sbjct: 955 PYNDKQAEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKL 999
>gi|190358534 SWI/SNF-related, matrix-associated actin-dependent
regulator of chromatin, subfamily a, containing DEAD/H
box 1 isoform b [Homo sapiens]
Length = 1026
Score = 271 bits (693), Expect = 4e-72
Identities = 180/525 (34%), Positives = 266/525 (50%), Gaps = 78/525 (14%)
Query: 725 TLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLVSAPL 784
+L PYQ GLNWL G + ILADEMGLGKT+Q FL LY+EG++ GP L+ P
Sbjct: 496 SLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLYQEGNN-GPHLIVVPA 554
Query: 785 STIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFS-FEDNAIRGGKKASRMKKEASV 843
STI NW RE +W P + V+ Y G ++ R IR N S +ED
Sbjct: 555 STIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYED------------------ 596
Query: 844 KFHVLLTSYELI---TIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNGYSLQHKLLL 900
++V++T+Y + D ++ + I DE H LKN S ++ L + ++LLL
Sbjct: 597 -YNVIVTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLL 655
Query: 901 TGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEF----------ADIAKEDQIKKLHDML 950
TGTP+QNNL EL LLNF+ P F + + I ++++I ++
Sbjct: 656 TGTPVQNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQII 715
Query: 951 GPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGGNQVSLLN 1010
P +LRR+K +V K +P K + I +S Q++ Y + R +++N + N
Sbjct: 716 KPFILRRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSIN--NLEKNTEMCN 773
Query: 1011 VVMDLKKCCNHPYLF-------------------PVAAMEAPKM---------------- 1035
V+M L+K NHP L P P +
Sbjct: 774 VMMQLRKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVL 833
Query: 1036 ------PNGMYDGSALIRASGKLLLLQKMLKNLKEGGHRVLIFSQMTKMLDLLEDFLEHE 1089
N LI SGK +L +L LK+ G RV++FSQ T MLD+LE L+H
Sbjct: 834 CKQYRHINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHH 893
Query: 1090 GYKYERIDGGITGNMRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIYDSDWN 1149
++Y R+DG + R ID FN F FLLST+AGGLGINL +A+ VI++D D N
Sbjct: 894 QHRYLRLDGKTQISERIHLIDEFNT-DMDIFVFLLSTKAGGLGINLTSANVVILHDIDCN 952
Query: 1150 PHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKKKMML 1194
P+ND QA R HR+GQ K+V++ + +++ ++EE + ++ ++K+ L
Sbjct: 953 PYNDKQAEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKL 997
>gi|21914927 helicase, lymphoid-specific [Homo sapiens]
Length = 838
Score = 269 bits (687), Expect = 2e-71
Identities = 203/658 (30%), Positives = 312/658 (47%), Gaps = 130/658 (19%)
Query: 714 RQPEYLDATGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGH 773
+QP++ TGG + YQ+EG+ WLR W G + ILADEMGLGKTVQ + + + G
Sbjct: 213 QQPKHF--TGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRG- 269
Query: 774 SKGPFLVSAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKK 833
GPFLV PLST+ NW EF+ + PD+ + Y G ++ R + N +
Sbjct: 270 VPGPFLVCGPLSTLPNWMAEFKRFTPDIPTMLYHGTQEERQKLVRNIY------------ 317
Query: 834 ASRMKKEASVKFH-VLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFR----- 887
K++ +++ H V++TS+E+ D L W LIVDE HR+KN + + R
Sbjct: 318 ----KRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRF 373
Query: 888 ------VLNGYSLQHKLLLTGTPLQNNLEELFHLL-----------------NFLTPERF 924
+L G LQ+ L + L L ++F L + + ER
Sbjct: 374 NADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKERE 433
Query: 925 HNLEGFLEEF----------ADIAKE----------DQIKKLHDMLGPHMLRRLKADVFK 964
N+ L + +D+A E + K ++ ++ R A++F
Sbjct: 434 QNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFG 493
Query: 965 NMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGGNQ------------------- 1005
+ +T +ELSP + + + N+ ++ +
Sbjct: 494 SSEKET-----IELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVDRERAVVEV 548
Query: 1006 ---------VSLLNVVMDLKKCCNHPYLFPVAAMEAPKMP--NGMYDGSALIRASGKLLL 1054
+ L N++M L+KCCNHPYL +E P P L+ SGK L+
Sbjct: 549 NIPVESEVNLKLQNIMMLLRKCCNHPYL-----IEYPIDPVTQEFKIDEELVTNSGKFLI 603
Query: 1055 LQKMLKNLKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNA 1114
L +ML LK+ GH+VL+FSQMT MLD+L D+ + + R+DG ++ + R++ + FN
Sbjct: 604 LDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHSFNT 663
Query: 1115 PGAQQFCFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRF 1174
+ F FL+STRAGGLGINL ADTVIIYDSDWNP +D+QA R HRIGQ K V++YR
Sbjct: 664 D-PEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRL 722
Query: 1175 VTRASVEERITQVAKKKMMLTHLVV--------RPGLGSKTGSMSKQELDDILKFGTEEL 1226
VT +++++I + A K L L++ + GL + +EL ++LK E
Sbjct: 723 VTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDYE- 781
Query: 1227 FKDEATDGGGDNKEGEDSSVIHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQ 1284
+E + S DK +E LLDR+ + + E + FK+ +
Sbjct: 782 ------------REIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILE 827
>gi|4557565 excision repair cross-complementing rodent repair
deficiency, complementation group 6 [Homo sapiens]
Length = 1493
Score = 253 bits (647), Expect = 1e-66
Identities = 166/506 (32%), Positives = 257/506 (50%), Gaps = 55/506 (10%)
Query: 726 LHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSL-YKEGHSKG-------- 776
L YQ G+ WL Q IL DEMGLGKT+Q FL L Y + ++G
Sbjct: 507 LFKYQQTGVRWLWELHCQQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRFEGL 566
Query: 777 -PFLVSAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKAS 835
P ++ P + + W +EF W P V AI+ E K
Sbjct: 567 GPTVIVCPTTVMHQWVKEFHTWWPPFRV----------AILHETGSYTH--------KKE 608
Query: 836 RMKKEASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNGYSLQ 895
++ ++ + +L+TSY I + + DW +I+DE H+++N + +
Sbjct: 609 KLIRDVAHCHGILITSYSYIRLMQDDISRYDWHYVILDEGHKIRNPNAAVTLACKQFRTP 668
Query: 896 HKLLLTGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFA--------DIAKEDQIKK-- 945
H+++L+G+P+QNNL EL+ L +F+ P + L F+E+F+ A Q+K
Sbjct: 669 HRIILSGSPMQNNLRELWSLFDFIFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVKTAY 728
Query: 946 -----LHDMLGPHMLRRLKADVFKNM--PSKTELIVRVELSPMQKKYYKYILTRN--FEA 996
L D + P++LRR+K+DV ++ P K E ++ L+ Q K Y+ + +
Sbjct: 729 KCACVLRDTINPYLLRRMKSDVKMSLSLPDKNEQVLFCRLTDEQHKVYQNFVDSKEVYRI 788
Query: 997 LNARGGGNQVSLLNVVMDLKKCCNHPYLFPVAAMEAPKMPNGMY--DGSALIRASGKLLL 1054
LN ++ + + ++ L+K CNHP LF +P+ D + SGK+++
Sbjct: 789 LNG-----EMQIFSGLIALRKICNHPDLFSGGPKNLKGLPDDELEEDQFGYWKRSGKMIV 843
Query: 1055 LQKMLKNLKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNA 1114
++ +LK + G RVL+FSQ +MLD+LE FL + Y Y ++DG T RQ I R+N
Sbjct: 844 VESLLKIWHKQGQRVLLFSQSRQMLDILEVFLRAQKYTYLKMDGTTTIASRQPLITRYNE 903
Query: 1115 PGAQQFCFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRF 1174
F FLL+TR GGLG+NL A+ V+IYD DWNP D QA RA RIGQ K+V +YR
Sbjct: 904 D-TSIFVFLLTTRVGGLGVNLTGANRVVIYDPDWNPSTDTQARERAWRIGQKKQVTVYRL 962
Query: 1175 VTRASVEERITQVAKKKMMLTHLVVR 1200
+T ++EE+I K LT+ V++
Sbjct: 963 LTAGTIEEKIYHRQIFKQFLTNRVLK 988
>gi|216548193 RAD54-like protein [Homo sapiens]
Length = 747
Score = 221 bits (564), Expect = 4e-57
Identities = 161/549 (29%), Positives = 263/549 (47%), Gaps = 53/549 (9%)
Query: 689 LKKVKLRKLERPPETPTVDPTVKYERQPEYL---DATGGTLHPYQMEGLNWL-------R 738
L+K L E PP + + E+ P ++ L P+Q EG+ +L R
Sbjct: 113 LEKDALVLYEPPPLSAHDQLKLDKEKLPVHVVVDPILSKVLRPHQREGVKFLWECVTSRR 172
Query: 739 FSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFL----VSAPLSTIINWEREF 794
+ G I+ADEMGLGKT+Q +++L ++ P + V +P S + NW E
Sbjct: 173 IPGSHGC--IMADEMGLGKTLQCITLMWTLLRQSPECKPEIDKAVVVSPSSLVKNWYNEV 230
Query: 795 EMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASRMKKEASVKFHVLLTSYEL 854
W +G + I D + G ++ A V +L+ SYE
Sbjct: 231 GKW---------LGGRIQPLAIDGGSKDEIDQKLEGFMN----QRGARVSSPILIISYET 277
Query: 855 ITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNGYSLQHKLLLTGTPLQNNLEELFH 914
+ + +L +I DE HRLKN++++ ++ L+ + ++L++GTP+QN+L E F
Sbjct: 278 FRLHVGVLQKGSVGLVICDEGHRLKNSENQTYQALDSLNTSRRVLISGTPIQNDLLEYFS 337
Query: 915 LLNFLTPERFHNLEGFLEEFA-------DIAK--------EDQIKKLHDMLGPHMLRRLK 959
L++F+ F + F D A E+++++L ++ ++RR
Sbjct: 338 LVHFVNSGILGTAHEFKKHFELPILKGRDAAASEADRQLGEERLRELTSIVNRCLIRRTS 397
Query: 960 ADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGGNQVSLLNVVMDLKKCC 1019
+ K +P K E +V L+P+Q + YK L + A G VS L+ + LKK C
Sbjct: 398 DILSKYLPVKIEQVVCCRLTPLQTELYKRFLRQAKPAEELLEGKMSVSSLSSITSLKKLC 457
Query: 1020 NHPYLFPVAAMEAPK--------MPNGMYDGSALIRASGKLLLLQKMLKNLKE-GGHRVL 1070
NHP L +E P G + + SGK+L+L +L + +V+
Sbjct: 458 NHPALIYDKCVEEEDGFVGALDLFPPGYSSKALEPQLSGKMLVLDYILAVTRSRSSDKVV 517
Query: 1071 IFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFCFLLSTRAGG 1130
+ S T+ LDL E Y Y R+DG ++ R + ++RFN+P + F F+LS++AGG
Sbjct: 518 LVSNYTQTLDLFEKLCRARRYLYVRLDGTMSIKKRAKVVERFNSPSSPDFVFMLSSKAGG 577
Query: 1131 LGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKK 1190
G+NL A+ ++++D DWNP ND QA +R R GQ K IYR ++ ++EE+I Q
Sbjct: 578 CGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTCYIYRLLSAGTIEEKIFQRQSH 637
Query: 1191 KMMLTHLVV 1199
K L+ VV
Sbjct: 638 KKALSSCVV 646
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,514,851
Number of Sequences: 37866
Number of extensions: 4799574
Number of successful extensions: 57376
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 428
Number of HSP's successfully gapped in prelim test: 1023
Number of HSP's that attempted gapping in prelim test: 31513
Number of HSP's gapped (non-prelim): 18421
length of query: 1912
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1795
effective length of database: 13,817,196
effective search space: 24801866820
effective search space used: 24801866820
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.