BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|51479177 iroquois homeobox protein 1 [Homo sapiens] (480 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|51479177 iroquois homeobox protein 1 [Homo sapiens] 984 0.0 gi|226371735 iroquois homeobox 3 [Homo sapiens] 326 3e-89 gi|197100900 iroquois homeobox 2 [Homo sapiens] 205 8e-53 gi|39930475 iroquois homeobox 2 [Homo sapiens] 205 8e-53 gi|7705555 iroquois homeobox 4 [Homo sapiens] 199 4e-51 gi|42544241 iroquois homeobox protein 6 [Homo sapiens] 197 2e-50 gi|139394646 iroquois homeobox protein 5 [Homo sapiens] 190 2e-48 gi|178057337 mohawk homeobox [Homo sapiens] 78 2e-14 gi|89257348 homeo box HB9 [Homo sapiens] 59 1e-08 gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Hom... 59 1e-08 gi|28866955 PBX/knotted 1 homeobox 1 [Homo sapiens] 58 2e-08 gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Hom... 58 2e-08 gi|28178843 TG-interacting factor isoform a [Homo sapiens] 57 4e-08 gi|4507473 TG-interacting factor isoform c [Homo sapiens] 57 4e-08 gi|28178855 TG-interacting factor isoform d [Homo sapiens] 57 4e-08 gi|28178853 TG-interacting factor isoform d [Homo sapiens] 57 4e-08 gi|28178851 TG-interacting factor isoform d [Homo sapiens] 57 4e-08 gi|28178857 TG-interacting factor isoform d [Homo sapiens] 57 4e-08 gi|28178849 TG-interacting factor isoform c [Homo sapiens] 57 4e-08 gi|28178845 TG-interacting factor isoform b [Homo sapiens] 57 4e-08 gi|116812644 PBX/knotted 1 homeobox 2 [Homo sapiens] 57 4e-08 gi|34328941 TGFB-induced factor homeobox 2-like, X-linked [Homo ... 57 5e-08 gi|122937321 UNC homeobox [Homo sapiens] 56 8e-08 gi|57863279 Meis1, myeloid ecotropic viral integration site 1 ho... 55 1e-07 gi|11141881 TGFB-induced factor homeobox 2 [Homo sapiens] 55 1e-07 gi|163965366 nascent polypeptide-associated complex alpha subuni... 54 2e-07 gi|40354216 sine oculis homeobox homolog 5 [Homo sapiens] 54 2e-07 gi|85068580 homeobox B7 [Homo sapiens] 54 4e-07 gi|27502383 Meis homeobox 2 isoform h [Homo sapiens] 53 5e-07 gi|27502381 Meis homeobox 2 isoform g [Homo sapiens] 53 5e-07 >gi|51479177 iroquois homeobox protein 1 [Homo sapiens] Length = 480 Score = 984 bits (2543), Expect = 0.0 Identities = 480/480 (100%), Positives = 480/480 (100%) Query: 1 MSFPQLGYPQYLSAAGPGAYGGERPGVLAAAAAAAAAASSGRPGAAELGGGAGAAAVTSV 60 MSFPQLGYPQYLSAAGPGAYGGERPGVLAAAAAAAAAASSGRPGAAELGGGAGAAAVTSV Sbjct: 1 MSFPQLGYPQYLSAAGPGAYGGERPGVLAAAAAAAAAASSGRPGAAELGGGAGAAAVTSV 60 Query: 61 LGMYAAAGPYAGAPNYSAFLPYAADLSLFSQMGSQYELKDNPGVHPATFAAHTAPAYYPY 120 LGMYAAAGPYAGAPNYSAFLPYAADLSLFSQMGSQYELKDNPGVHPATFAAHTAPAYYPY Sbjct: 61 LGMYAAAGPYAGAPNYSAFLPYAADLSLFSQMGSQYELKDNPGVHPATFAAHTAPAYYPY 120 Query: 121 GQFQYGDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFAN 180 GQFQYGDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFAN Sbjct: 121 GQFQYGDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFAN 180 Query: 181 ARRRLKKENKVTWGARSKDQEDGALFGSDTEGDPEKAEDDEEIDLESIDIDKIDEHDGDQ 240 ARRRLKKENKVTWGARSKDQEDGALFGSDTEGDPEKAEDDEEIDLESIDIDKIDEHDGDQ Sbjct: 181 ARRRLKKENKVTWGARSKDQEDGALFGSDTEGDPEKAEDDEEIDLESIDIDKIDEHDGDQ 240 Query: 241 SNEDDEDKAEAPHAPAAPSALARDQGSPLAAADVLKPQDSPLGLAKEAPEPGSTRLLSPG 300 SNEDDEDKAEAPHAPAAPSALARDQGSPLAAADVLKPQDSPLGLAKEAPEPGSTRLLSPG Sbjct: 241 SNEDDEDKAEAPHAPAAPSALARDQGSPLAAADVLKPQDSPLGLAKEAPEPGSTRLLSPG 300 Query: 301 AAAGGLQGAPHGKPKIWSLAETATSPDGAPKASPPPPAGHPGAHGPSAGAPLQHPAFLPS 360 AAAGGLQGAPHGKPKIWSLAETATSPDGAPKASPPPPAGHPGAHGPSAGAPLQHPAFLPS Sbjct: 301 AAAGGLQGAPHGKPKIWSLAETATSPDGAPKASPPPPAGHPGAHGPSAGAPLQHPAFLPS 360 Query: 361 HGLYTCHIGKFSNWTNSAFLAQGSLLNMRSFLGVGAPHAAPHGPHLPAPPPPQPPVAIAP 420 HGLYTCHIGKFSNWTNSAFLAQGSLLNMRSFLGVGAPHAAPHGPHLPAPPPPQPPVAIAP Sbjct: 361 HGLYTCHIGKFSNWTNSAFLAQGSLLNMRSFLGVGAPHAAPHGPHLPAPPPPQPPVAIAP 420 Query: 421 GALNGDKASVRSSPTLPERDLVPRPDSPAQQLKSPFQPVRDNSLAPQEGTPRILAALPSA 480 GALNGDKASVRSSPTLPERDLVPRPDSPAQQLKSPFQPVRDNSLAPQEGTPRILAALPSA Sbjct: 421 GALNGDKASVRSSPTLPERDLVPRPDSPAQQLKSPFQPVRDNSLAPQEGTPRILAALPSA 480 >gi|226371735 iroquois homeobox 3 [Homo sapiens] Length = 501 Score = 326 bits (836), Expect = 3e-89 Identities = 223/508 (43%), Positives = 276/508 (54%), Gaps = 76/508 (14%) Query: 1 MSFPQLGYPQYLSAAGPGAYGGERPGVLAAAAAAAAAASSGRPGAAELGG-GAGAAAVTS 59 MSFPQLGY QY+ Y ERPG + +A A GA+EL G+ + ++S Sbjct: 1 MSFPQLGY-QYIRPL----YPSERPGAAGGSGGSAGARGGLGAGASELNASGSLSNVLSS 55 Query: 60 VLGM-YAAAGPYAGAPNYSAFLPYAADLSLFSQMGSQYELKDNPGV-HPATFAA--HTAP 115 V G YAAA A A Y AFLPYAA+L +F Q+G+QYELKD+PGV HPA AA H P Sbjct: 56 VYGAPYAAAAAAAAAQGYGAFLPYAAELPIFPQLGAQYELKDSPGVQHPAAAAAFPHPHP 115 Query: 116 AYYPYGQFQYGDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVS 175 A+YPYGQ+Q+GDP RPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVS Sbjct: 116 AFYPYGQYQFGDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVS 175 Query: 176 TWFANARRRLKKENKVTWGARSKDQEDGALFGSDTEGDPEKAEDDE---EIDLESIDIDK 232 TWFANARRRLKKENK+TW RS+ E+G +GS+ E + E+ ++++ E++LE ++ Sbjct: 176 TWFANARRRLKKENKMTWAPRSRTDEEGNAYGSEREEEDEEEDEEDGKRELELEEEELGG 235 Query: 233 IDEHDGDQSNEDDEDKAE---------APHAPAAPSALARDQG----SPLAAADVLKPQD 279 +E G + DD++ E A + + AR G P++ + +D Sbjct: 236 EEEDTGGEGLADDDEDEEIDLENLDGAATEPELSLAGAARRDGDLGLGPISDSKNSDSED 295 Query: 280 S-------PLGLAKEAPEPGSTRLLSPG---------------AAAGGLQGAPHGKPKIW 317 S PL + AP P + SP A A LQ KPKIW Sbjct: 296 SSEGLEDRPLPVLSLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASALQ-----KPKIW 350 Query: 318 SLAETATSPDGAPKASPPPPAGHP--GAHGPSAGAPLQHPAFLPSHGLYTCHIGKFSNWT 375 SLAETATSPD P+ SPP G P A PSA A +H L + +GKF WT Sbjct: 351 SLAETATSPDN-PRRSPPGAGGSPPGAAVAPSALQLSPAAAAAAAHRLVSAPLGKFPAWT 409 Query: 376 NSAFLA--QGSLLNMRSFLGVGAPHAAPHGPHLPAPPPPQPPVAIAPGALNGDKASVRSS 433 N F G L+ S LG PH L P P A A+ + Sbjct: 410 NRPFPGPPPGPRLHPLSLLGSAPPHL------LGLPGAAGHPAA----------AAAFAR 453 Query: 434 PTLPE--RDLVPRPDSPAQQLKSPFQPV 459 P PE D + + LK+ FQPV Sbjct: 454 PAEPEGGTDRCSALEVEKKLLKTAFQPV 481 >gi|197100900 iroquois homeobox 2 [Homo sapiens] Length = 471 Score = 205 bits (521), Expect = 8e-53 Identities = 166/454 (36%), Positives = 218/454 (48%), Gaps = 101/454 (22%) Query: 17 PGAYGGERPGVLAAAAAAAAAASS-GRPGAAELGGGAGAAAVTSVLGMYAAAGPYAGAPN 75 P Y + PG LA + A AS+ P + EL A +A + G +AA A Sbjct: 4 PQGYLYQAPGSLALYSCPAYGASALAAPRSEELARSASGSAFSPYPG--SAAFTAQAATG 61 Query: 76 YSAFLPYAADLSLFSQMGSQYELKDNPGVHPATFAAHT-----APAYYPYGQ----FQYG 126 + + L Y+AD + + P A + AHT A +Y+PYG +Q Sbjct: 62 FGSPLQYSADAAAAAA--------GFPSYMGAPYDAHTTGMTGAISYHPYGSAAYPYQLN 113 Query: 127 DPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLK 186 DP KNATR++T+TLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLK Sbjct: 114 DPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLK 173 Query: 187 KENKVTWGARSKDQEDGALFGSDT---EGDPEKAEDDEEIDLE----SIDIDKIDEH--- 236 KENK+TW R+K +++ G T + P+KA++ E E S+ +D + +H Sbjct: 174 KENKMTWAPRNKSEDEDEDEGDATRSKDESPDKAQEGTETSAEDEGISLHVDSLTDHSCS 233 Query: 237 ---DGD------------------------QSNEDDEDKAEAPHAPAAPSALARDQGSPL 269 DG+ + +EDD+++ E AP P SPL Sbjct: 234 AESDGEKLPCRAGDPLCESGSECKDKYDDLEDDEDDDEEGERGLAPPKPVT-----SSPL 288 Query: 270 AAADV----LKPQDSPLGLAKEAPEPGSTRLLSPGAAAGGLQGAPHGKPKIWSLAETATS 325 + P+ +P G ++ P+ T SPGA P KPK+WSLAE ATS Sbjct: 289 TGLEAPLLSPPPEAAPRG-GRKTPQGSRT---SPGAP------PPASKPKLWSLAEIATS 338 Query: 326 ------------PDGAPKASPP-----PPAGHPGAHGPSAGAPLQHPAFLPSHGLYTCHI 368 P G P A+ P PP G P P G PL + + P +G YT Sbjct: 339 DLKQPSLGPGCGPPGLPAAAAPASTGAPPGGSPYPASPLLGRPLYYTS--PFYGNYT--- 393 Query: 369 GKFSNWTNSAFLAQGSLLNMRSFLGVG-APHAAP 401 + N N+A QG L + G A H AP Sbjct: 394 -NYGN-LNAALQGQGLLRYNSAAAAPGEALHTAP 425 >gi|39930475 iroquois homeobox 2 [Homo sapiens] Length = 471 Score = 205 bits (521), Expect = 8e-53 Identities = 166/454 (36%), Positives = 218/454 (48%), Gaps = 101/454 (22%) Query: 17 PGAYGGERPGVLAAAAAAAAAASS-GRPGAAELGGGAGAAAVTSVLGMYAAAGPYAGAPN 75 P Y + PG LA + A AS+ P + EL A +A + G +AA A Sbjct: 4 PQGYLYQAPGSLALYSCPAYGASALAAPRSEELARSASGSAFSPYPG--SAAFTAQAATG 61 Query: 76 YSAFLPYAADLSLFSQMGSQYELKDNPGVHPATFAAHT-----APAYYPYGQ----FQYG 126 + + L Y+AD + + P A + AHT A +Y+PYG +Q Sbjct: 62 FGSPLQYSADAAAAAA--------GFPSYMGAPYDAHTTGMTGAISYHPYGSAAYPYQLN 113 Query: 127 DPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLK 186 DP KNATR++T+TLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLK Sbjct: 114 DPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLK 173 Query: 187 KENKVTWGARSKDQEDGALFGSDT---EGDPEKAEDDEEIDLE----SIDIDKIDEH--- 236 KENK+TW R+K +++ G T + P+KA++ E E S+ +D + +H Sbjct: 174 KENKMTWAPRNKSEDEDEDEGDATRSKDESPDKAQEGTETSAEDEGISLHVDSLTDHSCS 233 Query: 237 ---DGD------------------------QSNEDDEDKAEAPHAPAAPSALARDQGSPL 269 DG+ + +EDD+++ E AP P SPL Sbjct: 234 AESDGEKLPCRAGDPLCESGSECKDKYDDLEDDEDDDEEGERGLAPPKPVT-----SSPL 288 Query: 270 AAADV----LKPQDSPLGLAKEAPEPGSTRLLSPGAAAGGLQGAPHGKPKIWSLAETATS 325 + P+ +P G ++ P+ T SPGA P KPK+WSLAE ATS Sbjct: 289 TGLEAPLLSPPPEAAPRG-GRKTPQGSRT---SPGAP------PPASKPKLWSLAEIATS 338 Query: 326 ------------PDGAPKASPP-----PPAGHPGAHGPSAGAPLQHPAFLPSHGLYTCHI 368 P G P A+ P PP G P P G PL + + P +G YT Sbjct: 339 DLKQPSLGPGCGPPGLPAAAAPASTGAPPGGSPYPASPLLGRPLYYTS--PFYGNYT--- 393 Query: 369 GKFSNWTNSAFLAQGSLLNMRSFLGVG-APHAAP 401 + N N+A QG L + G A H AP Sbjct: 394 -NYGN-LNAALQGQGLLRYNSAAAAPGEALHTAP 425 >gi|7705555 iroquois homeobox 4 [Homo sapiens] Length = 519 Score = 199 bits (507), Expect = 4e-51 Identities = 180/525 (34%), Positives = 226/525 (43%), Gaps = 126/525 (24%) Query: 1 MSFPQLGYPQYLSAAGPGAYGGERPGVLAAAAAAAAAASSGRPGAAELGGGAGAAAVT-- 58 MS+PQ GYP Y SA P L A + + SG A+ G A A A Sbjct: 1 MSYPQFGYP-YSSA----------PQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYC 49 Query: 59 ------------------SVLGMYAAAGPYAGAPNYSAFLPYAADLSLFSQMGSQYELKD 100 + LG+Y GPY G+ Y ++ Y ++ S F + S ++ KD Sbjct: 50 PVYESRLLATARHELNSAAALGVYG--GPYGGSQGYGNYVTYGSEASAFYSLNS-FDSKD 106 Query: 101 NPGVHPATFAAHTAPAYYPY----GQFQYGDPG------RPKNATRESTSTLKAWLNEHR 150 G A A AYYPY GQ+ Y G R KNATRE+TSTLKAWL EHR Sbjct: 107 GSGSAHGGLAP-AAAAYYPYEPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHR 165 Query: 151 KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSK--DQEDGALFGS 208 KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENK+TW R+K D++ G Sbjct: 166 KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGE 225 Query: 209 DTEGDPEKAEDD-------------EEIDLESIDIDKIDEHDGDQS--------NEDDED 247 + EG E+A ++ EE +LE D+D D + + + D Sbjct: 226 EEEGGEEEAREEPLKSSKNAEPVGKEEKELELSDLDDFDPLEAEPPACELKPPFHSLDGG 285 Query: 248 KAEAPHAPAAP-------SALARDQGSPLAAADVLKPQDSPLGLAKEAPEP-----GSTR 295 P AP P ++ G A + L+ S L A PEP G + Sbjct: 286 LERVPAAPDGPVKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPLPGAEGGPQ 345 Query: 296 LLS------PGAAAGGLQGAPHGKPKIWSLAETATSPDGA--------------PKASPP 335 + P A+ GL+ KP+IWSLA TAT+ A + P Sbjct: 346 VCEAKLGFVPAGASAGLE----AKPRIWSLAHTATAAAAAATSLSQTEFPSCMLKRQGPA 401 Query: 336 PPAGHPGAHGPSAGAPLQHPAFLPSHGLYTCHIGKFSNWTNSAF---------------L 380 PA A S L H L H + NW + F Sbjct: 402 APAAVSSAPATSPSVALPHSGALDRH--QDSPVTSLRNWVDGVFHDPILRHSTLNQAWAT 459 Query: 381 AQGSLLN---MRSFLGVGAPHAAPHGPHLPAPPPPQPPVAIAPGA 422 A+G+LL+ + LG GA P A PP P A A GA Sbjct: 460 AKGALLDPGPLGRSLGAGANVLT--APLARAFPPAVPQDAPAAGA 502 >gi|42544241 iroquois homeobox protein 6 [Homo sapiens] Length = 446 Score = 197 bits (501), Expect = 2e-50 Identities = 153/380 (40%), Positives = 195/380 (51%), Gaps = 51/380 (13%) Query: 1 MSFPQLGYP-----QYLSAAGPGAY---GGERPGVLAAAAAAAAAASSGRPGAAELGGGA 52 MSFP G+P Q+L++A +R A+ + A A P + L G A Sbjct: 1 MSFPHFGHPYRGASQFLASASSSTTCCESTQRSVSDVASGSTPAPALCCAPYDSRLLGSA 60 Query: 53 GAAAVTSVLGMYAAAGPYAGAP---NYSAFLPYAADL-SLFSQMGSQYELKDNPGVHPAT 108 + + LG+Y A PYA A +Y +LPY+ + SL+ + QYE K+ G ++ Sbjct: 61 -RPELGAALGIYGA--PYAAAAAAQSYPGYLPYSPEPPSLYGALNPQYEFKEAAGSFTSS 117 Query: 109 FAAHTAPAYYPY----GQFQY--------GDPGRPKNATRESTSTLKAWLNEHRKNPYPT 156 A AYYPY GQ+QY GR KNATRE+TSTLKAWLNEHRKNPYPT Sbjct: 118 LAQ--PGAYYPYERTLGQYQYERYGAVELSGAGRRKNATRETTSTLKAWLNEHRKNPYPT 175 Query: 157 KGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKDQEDGALFGSD------- 209 KGEKIMLAIITKMTLTQVSTWFANARRRLKKENK+TW ++K E+ G + Sbjct: 176 KGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEERKAEGGEEDSLGCL 235 Query: 210 TEGDPEKAEDDEEIDLESIDIDKIDEHDGDQSN-EDDEDKAEAPHAPAAPSALARDQGSP 268 T E E L D++ ++E + ++ ED+E A A A+ P Sbjct: 236 TADTKEVTASQEARGLRLSDLEDLEEEEEEEEEAEDEEVVATAGDRLTEFRKGAQSLPGP 295 Query: 269 LAAADVLKPQDSPLGLAKEAPE------PGSTRLLSPGAAAGGLQGAPH----GKPKIWS 318 AAA + + GLA AP GS A G + H KP+IWS Sbjct: 296 CAAAREGRLERRECGLA--APRFSFNDPSGSEEADFLSAETGSPRLTMHYPCLEKPRIWS 353 Query: 319 LAETATSP--DGAPKASPPP 336 LA TAT+ +GAP A P P Sbjct: 354 LAHTATASAVEGAPPARPRP 373 >gi|139394646 iroquois homeobox protein 5 [Homo sapiens] Length = 483 Score = 190 bits (483), Expect = 2e-48 Identities = 170/466 (36%), Positives = 215/466 (46%), Gaps = 94/466 (20%) Query: 1 MSFPQLGYPQYLSAAGPGAYGGERPGVLAAAAAAAAAASSGRPGAAELGGGAGAAAVTSV 60 MS+PQ GY SA+ L + A + + SG P ELG + +A + Sbjct: 1 MSYPQ-GYLYQPSASL----------ALYSCPAYSTSVISG-PRTDELGRSSSGSAFSPY 48 Query: 61 LGMYAAAGPYAGAPNYSAFLPYAAD------LSLFSQMGSQYE----LKDNPGVHPATFA 110 G A P +P Y++ L Y AD + S +GS Y+ + + G HP +A Sbjct: 49 AGSTAFTAP---SPGYNSHLQYGADPAAAAAAAFSSYVGSPYDHTPGMAGSLGYHP--YA 103 Query: 111 AHTAPAYYPYGQFQYGDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMT 170 A P G + YGDP KNATR++T+TLKAWLNEHRKNPYPTKGEKIMLAIITKMT Sbjct: 104 A-------PLGSYPYGDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMT 156 Query: 171 LTQVSTWFANARRRLKKENKVTWGARSKDQEDGALFGSDTEGDPEKAEDDEEIDLESIDI 230 LTQVSTWFANARRRLKKENK+TW R++ +++ E++E IDLE D Sbjct: 157 LTQVSTWFANARRRLKKENKMTWTPRNRSEDE---------------EEEENIDLEKNDE 201 Query: 231 DKIDEHDGDQSNEDDEDKAEAPHA----PAAPSALARDQGSPLAAADVLKPQDSPLGLAK 286 D + +D+ E P A A S R QG P A + S K Sbjct: 202 D-------EPQKPEDKGDPEGPEAGGAEQKAASGCERLQGPPTPAGKETEGSLSDSDF-K 253 Query: 287 EAPEPGSTRLLSPGAAAGGLQGAPHGKPKIWSLAETATS--PDGAPKASPPPPAGH--PG 342 E P G L GG +P G P LAE P GAP P P AG PG Sbjct: 254 EPPSEGRLDALQGPPRTGG--PSPAG-PAAARLAEDPAPHYPAGAPAPGPHPAAGEVPPG 310 Query: 343 AHGPS---AGAPLQHPAFLPSHGLYTCHIGKFSNWTNSAFLAQGSLLNMRSFLGVGAPHA 399 GPS + P PA L L++ LA+ + + + G G Sbjct: 311 PGGPSVIHSPPPPPPPAVLAKPKLWS--------------LAEIATSSDKVKDGGGGNEG 356 Query: 400 APHGPHLPAPPPPQPPVAIAPGALNGDKASVRSSPTLPERDLVPRP 445 + P PP P P IA AL G +AS +P+ P P Sbjct: 357 S------PCPPCPGP---IAGQALGGSRASPAPAPSRSPSAQCPFP 393 >gi|178057337 mohawk homeobox [Homo sapiens] Length = 352 Score = 77.8 bits (190), Expect = 2e-14 Identities = 49/123 (39%), Positives = 66/123 (53%), Gaps = 21/123 (17%) Query: 98 LKDNPGV-HPATFAAHTAPAYYPYGQFQYGDPGRPKNATRESTSTLKAWLNEHRKNPYPT 156 LKDN G+ H T A G + A ++ LK WL +HR NPYPT Sbjct: 51 LKDNLGLRHRRTGARQNG-----------GKVRHKRQALQDMARPLKQWLYKHRDNPYPT 99 Query: 157 KGEKIMLAIITKMTLTQVSTWFANARRRLK---KENKVTWGARSKDQEDGALFGSDTEGD 213 K EKI+LA+ ++MTL QVS WFANARRRLK ++ ++W R K L+ +G+ Sbjct: 100 KTEKILLALGSQMTLVQVSNWFANARRRLKNTVRQPDLSWALRIK------LYNKYVQGN 153 Query: 214 PEK 216 E+ Sbjct: 154 AER 156 >gi|89257348 homeo box HB9 [Homo sapiens] Length = 401 Score = 58.5 bits (140), Expect = 1e-08 Identities = 86/324 (26%), Positives = 120/324 (37%), Gaps = 58/324 (17%) Query: 9 PQYLSAAGPGA-----YGGER----PGVLAAAAAAAAAASSGRPGAAELGGGAGAAAVTS 59 P +L A G G +GG PG AAAAAAAAAA++G GGA A Sbjct: 94 PGFLGAGGGGGGTGGGHGGPHHHAHPGAAAAAAAAAAAAAAGGLALGLHPGGAQGGA--- 150 Query: 60 VLGMYAAAGPYAGAPNYSAFLPYAADLSLFSQMGSQYELKDNPGVHPA-----------T 108 G+ A A Y G P Y AA Y G HPA T Sbjct: 151 --GLPAQAALY-GHPVYGYSAAAAAAALAGQHPALSYSYPQVQGAHPAHPADPIKLGAGT 207 Query: 109 FA------AHTAPAYYPY-----GQFQ---YGDPGRPKNATRESTSTLKAWLNEHRKNPY 154 F A TA P Q Q G RP+ A ++ L ++ + N Y Sbjct: 208 FQLDQWLRASTAGMILPKMPDFNSQAQSNLLGKCRRPRTAF--TSQQLLELEHQFKLNKY 265 Query: 155 PTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKDQEDGALFGSDTEGDP 214 ++ ++ +A +T TQV WF N R + K+ K A + ++ G +G Sbjct: 266 LSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAKEQAAQEAEKQKGGGGGAGKGGA 325 Query: 215 EKAEDDEEIDLESIDIDKIDEHDG-------DQSNEDDEDKAEAPHAPAAPSALARDQGS 267 E+ +E + + D+ G D E+DED+ + H P + A Sbjct: 326 EEPGAEELLGPPAPG----DKGSGRRLRDLRDSDPEEDEDEDDEDHFPYSNGASVH---- 377 Query: 268 PLAAADVLKPQDSPLGLAKEAPEP 291 A++D DSP P P Sbjct: 378 -AASSDCSSEDDSPPPRPSHQPAP 400 Score = 31.6 bits (70), Expect = 1.7 Identities = 45/165 (27%), Positives = 55/165 (33%), Gaps = 23/165 (13%) Query: 268 PLAAADVLKPQDS--PLGLAKEA---PEPGSTRLLSPGAAAGGLQGAPHGKPKIWSLAET 322 P A AD L+ + P LA P+PG G GG G PH + A Sbjct: 66 PAAPADRLRAESPSPPRLLAAHCALLPKPGFLGAGGGGGGTGGGHGGPHHHAHPGAAAAA 125 Query: 323 ATSPDGAPKASPPPPAGHPGAHGPSAGAPLQHPAFLPSHGLYTCHIGKFSNWTNSAFLAQ 382 A + A A HPG AG P Q A L H +Y SA A Sbjct: 126 AAAA-AAAAAGGLALGLHPGGAQGGAGLPAQ--AALYGHPVY----------GYSAAAAA 172 Query: 383 GSLLNMRSFLGVGAPHAAPHGPHLPAPPPPQPPVAIAPGALNGDK 427 +L L P G H P P P+ + G D+ Sbjct: 173 AALAGQHPALSYSYPQV--QGAH---PAHPADPIKLGAGTFQLDQ 212 >gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Homo sapiens] Length = 377 Score = 58.5 bits (140), Expect = 1e-08 Identities = 79/354 (22%), Positives = 131/354 (37%), Gaps = 57/354 (16%) Query: 102 PGVHPATFAAHTAPAYYPYGQFQYGDPGRPKNATRESTST--LKAWLNEHRKNPYPTKGE 159 P VH T A A + +YG R + +R + + L+A +K YP Sbjct: 39 PSVHALTLAERLADIIL---EARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVM 95 Query: 160 KIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKDQEDGALFGSDTEGDPEKAED 219 + LA+ T + +V WF N R + +K+ + + + Q++ GS EG E Sbjct: 96 RERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEAE--GSHGEGKAEAPTP 153 Query: 220 DEEIDLE------------SIDIDKIDEHDGDQSNEDDEDKAEAPHAPAAPSALARDQGS 267 D ++D E + + ++ + + ED D+ E P A A + G+ Sbjct: 154 DTQLDTEQPPRLPGSDPPAELHLSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGA 213 Query: 268 PLAAADVLKPQDSPLGLAKEAPE---PGSTRLLSPGAAAGGLQGAPHGKP----KIWSLA 320 LG + +P+ PGS ++P A GGL G H ++ L Sbjct: 214 ----------DSKGLGCKRGSPKADSPGSL-TITPVAPGGGLLGPSHSYSSSPLSLFRLQ 262 Query: 321 ETATSPDGAPKASPPPPAGHPGAHGPSAGAPLQHPAFLPSHGLYTCHIGKFSNWTNSAFL 380 E A + G P+A A A +P G+ +G Sbjct: 263 EQFRQHMAATNNLVHYSSFEVGGPAPAAAAA---AAAVPYLGVNMAPLGS---------- 309 Query: 381 AQGSLLNMRSFLGVGAPHAAPHGPHLPAPPPPQPPVAIAPGA--LNGDKASVRS 432 L+ +S+ + AA H +P P PP +AP + LN S+ + Sbjct: 310 -----LHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTSIEN 358 >gi|28866955 PBX/knotted 1 homeobox 1 [Homo sapiens] Length = 436 Score = 57.8 bits (138), Expect = 2e-08 Identities = 27/63 (42%), Positives = 40/63 (63%), Gaps = 4/63 (6%) Query: 127 DPGRPKNAT----RESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANAR 182 D G KN + +T+ +++WL +H +PYPT+ EK +A T +TL QV+ WF NAR Sbjct: 255 DDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINAR 314 Query: 183 RRL 185 RR+ Sbjct: 315 RRI 317 >gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Homo sapiens] Length = 382 Score = 57.8 bits (138), Expect = 2e-08 Identities = 79/356 (22%), Positives = 132/356 (37%), Gaps = 56/356 (15%) Query: 102 PGVHPATFAAHTAPAYYP--YGQFQYGDPGRPKNATRESTST--LKAWLNEHRKNPYPTK 157 P VH T A A + + +YG R + +R + + L+A +K YP Sbjct: 39 PSVHALTLAERLAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDV 98 Query: 158 GEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKDQEDGALFGSDTEGDPEKA 217 + LA+ T + +V WF N R + +K+ + + + Q++ GS EG E Sbjct: 99 VMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEAE--GSHGEGKAEAP 156 Query: 218 EDDEEIDLE------------SIDIDKIDEHDGDQSNEDDEDKAEAPHAPAAPSALARDQ 265 D ++D E + + ++ + + ED D+ E P A A + Sbjct: 157 TPDTQLDTEQPPRLPGSDPPAELHLSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSP 216 Query: 266 GSPLAAADVLKPQDSPLGLAKEAPE---PGSTRLLSPGAAAGGLQGAPHGKP----KIWS 318 G+ LG + +P+ PGS ++P A GGL G H ++ Sbjct: 217 GA----------DSKGLGCKRGSPKADSPGSL-TITPVAPGGGLLGPSHSYSSSPLSLFR 265 Query: 319 LAETATSPDGAPKASPPPPAGHPGAHGPSAGAPLQHPAFLPSHGLYTCHIGKFSNWTNSA 378 L E A + G P+A A A +P G+ +G Sbjct: 266 LQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAA---AAAVPYLGVNMAPLGS-------- 314 Query: 379 FLAQGSLLNMRSFLGVGAPHAAPHGPHLPAPPPPQPPVAIAPGA--LNGDKASVRS 432 L+ +S+ + AA H +P P PP +AP + LN S+ + Sbjct: 315 -------LHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTSIEN 363 >gi|28178843 TG-interacting factor isoform a [Homo sapiens] Length = 401 Score = 57.0 bits (136), Expect = 4e-08 Identities = 28/60 (46%), Positives = 36/60 (60%) Query: 126 GDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 185 G R N +ES L+ WL EHR N YP++ EK +L+ T ++ QV WF NARRRL Sbjct: 163 GKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL 222 >gi|4507473 TG-interacting factor isoform c [Homo sapiens] Length = 272 Score = 57.0 bits (136), Expect = 4e-08 Identities = 28/60 (46%), Positives = 36/60 (60%) Query: 126 GDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 185 G R N +ES L+ WL EHR N YP++ EK +L+ T ++ QV WF NARRRL Sbjct: 34 GKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL 93 >gi|28178855 TG-interacting factor isoform d [Homo sapiens] Length = 252 Score = 57.0 bits (136), Expect = 4e-08 Identities = 28/60 (46%), Positives = 36/60 (60%) Query: 126 GDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 185 G R N +ES L+ WL EHR N YP++ EK +L+ T ++ QV WF NARRRL Sbjct: 14 GKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL 73 >gi|28178853 TG-interacting factor isoform d [Homo sapiens] Length = 252 Score = 57.0 bits (136), Expect = 4e-08 Identities = 28/60 (46%), Positives = 36/60 (60%) Query: 126 GDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 185 G R N +ES L+ WL EHR N YP++ EK +L+ T ++ QV WF NARRRL Sbjct: 14 GKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL 73 >gi|28178851 TG-interacting factor isoform d [Homo sapiens] Length = 252 Score = 57.0 bits (136), Expect = 4e-08 Identities = 28/60 (46%), Positives = 36/60 (60%) Query: 126 GDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 185 G R N +ES L+ WL EHR N YP++ EK +L+ T ++ QV WF NARRRL Sbjct: 14 GKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL 73 >gi|28178857 TG-interacting factor isoform d [Homo sapiens] Length = 252 Score = 57.0 bits (136), Expect = 4e-08 Identities = 28/60 (46%), Positives = 36/60 (60%) Query: 126 GDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 185 G R N +ES L+ WL EHR N YP++ EK +L+ T ++ QV WF NARRRL Sbjct: 14 GKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL 73 >gi|28178849 TG-interacting factor isoform c [Homo sapiens] Length = 272 Score = 57.0 bits (136), Expect = 4e-08 Identities = 28/60 (46%), Positives = 36/60 (60%) Query: 126 GDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 185 G R N +ES L+ WL EHR N YP++ EK +L+ T ++ QV WF NARRRL Sbjct: 34 GKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL 93 >gi|28178845 TG-interacting factor isoform b [Homo sapiens] Length = 286 Score = 57.0 bits (136), Expect = 4e-08 Identities = 28/60 (46%), Positives = 36/60 (60%) Query: 126 GDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 185 G R N +ES L+ WL EHR N YP++ EK +L+ T ++ QV WF NARRRL Sbjct: 48 GKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL 107 >gi|116812644 PBX/knotted 1 homeobox 2 [Homo sapiens] Length = 472 Score = 57.0 bits (136), Expect = 4e-08 Identities = 23/50 (46%), Positives = 36/50 (72%) Query: 136 RESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 185 + +T+ +++WL +H +PYPT+ EK +A T +TL QV+ WF NARRR+ Sbjct: 297 KHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRI 346 >gi|34328941 TGFB-induced factor homeobox 2-like, X-linked [Homo sapiens] Length = 241 Score = 56.6 bits (135), Expect = 5e-08 Identities = 37/129 (28%), Positives = 59/129 (45%), Gaps = 8/129 (6%) Query: 130 RPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL---- 185 R N ES L+ W+ +HR YP++ EK ML+ T ++L Q+S WF NARRR+ Sbjct: 53 RKGNLPAESVKILRDWMYKHRFKAYPSEEEKQMLSEKTNLSLLQISNWFINARRRILPDM 112 Query: 186 --KKENKVTWGARSKDQEDGALFGSDTEGDPEKAEDDEEIDLESIDIDKIDEHDGDQSNE 243 ++ N G ++ S P K+ +++S+ + + + G S E Sbjct: 113 LQQRRNDPIIGHKTGKDAHATHLQSTEASVPAKSGPSGPDNVQSLPLWPLPK--GQMSRE 170 Query: 244 DDEDKAEAP 252 D AP Sbjct: 171 KQPDPESAP 179 >gi|122937321 UNC homeobox [Homo sapiens] Length = 531 Score = 55.8 bits (133), Expect = 8e-08 Identities = 112/483 (23%), Positives = 166/483 (34%), Gaps = 90/483 (18%) Query: 48 LGGGAGAAAVTSVLGMYAAAGPYAGAPNYSAFLPYAADLSLFSQMGSQYELKDNPGVHPA 107 LGG G +Y AG + +A +P++ D L + + + + PA Sbjct: 18 LGGVVGFPYPLGHHHVYELAGHQLQSAAAAASVPFSIDGLLGGSCAAAASVVNPTPLLPA 77 Query: 108 TFAAHTAPAYYPYGQFQYGDPGR--PKNATRESTSTLKAWLNEH-----RKNPYPTKGEK 160 A P+ GDP + P R + + W E ++ YP + Sbjct: 78 --ACGVGGDGQPFKLSDSGDPDKESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMR 135 Query: 161 IMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKDQEDGALFGSDTEGDPEKAEDD 220 LA+ + ++V WF N R + +K+ G S DPE+ Sbjct: 136 EALALRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARK 195 Query: 221 EEIDLESIDIDKIDEHDGDQSNEDDEDKAEAPHAPAAPSALARDQGSPLAAADVLKPQDS 280 E ++K+++ + + + H+P G L +A Sbjct: 196 E--------LEKMEKKKRKHEKKLLKSQGRHLHSPG---------GLSLHSAPSSDSDSG 238 Query: 281 PLGLAKEAPEPGSTRLLSPGAAAGGLQG---APHGKPKIWSLAETATSPDGAPKASPPPP 337 GL+ E PEP PGA A G G AP G+P + A P A P P Sbjct: 239 GGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPR 298 Query: 338 AGHP-----GAHGP----------SAGAPLQHPAFLPSHGLYTCHIGKFSNWTNSAFLAQ 382 G P + GP +AG P P + S L + + +N+A A Sbjct: 299 PGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVES--LLSDSPPRRKAASNAAAAAA 356 Query: 383 GSL-------LNMRSFLGVG----APHAAPHGPHLP----------------APP----P 411 L R+ +G G P P G +P APP P Sbjct: 357 AGLDFAPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVP 416 Query: 412 PQPPVAIAPGALNG-----DKASVRSSPTLPERDLVPRPDSPAQQLKSPFQPVRDNSLAP 466 P PP + GA +G D A R SP D V P +PA +PF+ + S A Sbjct: 417 PAPPAQASFGAFSGPGGAPDSAFARRSP-----DAVASPGAPA-PAPAPFRDLA--SAAA 468 Query: 467 QEG 469 EG Sbjct: 469 TEG 471 Score = 30.4 bits (67), Expect = 3.7 Identities = 62/240 (25%), Positives = 81/240 (33%), Gaps = 58/240 (24%) Query: 252 PHAPAAPSALARDQGSPLAAAD---VLKPQDSPLG---LAKEAPEPGSTRLLSPGAAAGG 305 P PA A + G+ +AA + P+ SP L ++P + AAA G Sbjct: 299 PGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAASNAAAAAAAG 358 Query: 306 LQGAPHGKP--------KIWSLAETATSPDG----------------APKASPPPPAGHP 341 L AP G P K L T P G APK +PP PA P Sbjct: 359 LDFAP-GLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPP 417 Query: 342 --------GAHGPSAGAP-----LQHPAFLPSHGLYTCHIGKFSNWTNSAFLAQGSLLNM 388 GA GAP + P + S G F + ++A +G Sbjct: 418 APPAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAA-ATEG----- 471 Query: 389 RSFLGVGAPHAAPHGPHLPAPPPPQPPVAIAPGALNGDKASVRSSPTLPERDLVPRPDSP 448 G A G PAPPPP P + PG A ++ +PE P P Sbjct: 472 ------GGGDCADAGTAGPAPPPPAP--SPRPGPRPPSPAEEPATCGVPEPGAAAGPSPP 523 >gi|57863279 Meis1, myeloid ecotropic viral integration site 1 homolog 3 isoform 2 [Homo sapiens] Length = 358 Score = 55.1 bits (131), Expect = 1e-07 Identities = 31/85 (36%), Positives = 47/85 (55%), Gaps = 7/85 (8%) Query: 138 STSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRR-----LKKENKVT 192 +T+ ++AWL +H +PYP++ +K LA T +T+ QV+ WF NARRR + + N+ Sbjct: 256 ATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRTG 315 Query: 193 WGARSKDQEDGALFGSDTEGDPEKA 217 GA +G G TE P A Sbjct: 316 QGAAF--SPEGQPIGGYTETQPHVA 338 >gi|11141881 TGFB-induced factor homeobox 2 [Homo sapiens] Length = 237 Score = 55.1 bits (131), Expect = 1e-07 Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 9/89 (10%) Query: 126 GDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 185 G R N +ES L+ WL HR N YP++ EK+ L+ T +++ Q+ WF NARRRL Sbjct: 17 GKRKRRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTNLSVLQICNWFINARRRL 76 Query: 186 ---------KKENKVTWGARSKDQEDGAL 205 K N+ T R D AL Sbjct: 77 LPDMLRKDGKDPNQFTISRRGGKASDVAL 105 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 54.3 bits (129), Expect = 2e-07 Identities = 66/246 (26%), Positives = 91/246 (36%), Gaps = 42/246 (17%) Query: 252 PHAPAA-------PSALARDQGSPLAAADVLKPQDSP-LGLAKEAPEPGSTRLLS--PGA 301 P AP A P+ LA + A V P+ +P + KEAP S++ S P Sbjct: 1526 PIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV 1585 Query: 302 AAGGLQGAPHGKPKIWSLAETATSPDGAPKASPPPPAGHPGA--HGPSAGAPLQHPAFLP 359 +GAP PK + TSP +PK +P PPA P + GP+ AP P P Sbjct: 1586 TPSTYKGAP--SPKELLIPPAVTSP--SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPP 1641 Query: 360 -----------SHGLYTCHIGKFSNWTNSAFLAQGSLLNMRSFLGVGAPHAAP------- 401 S TC +G + A+ ++ L AP + P Sbjct: 1642 VTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTR 1701 Query: 402 HGPHLPAPPPPQPPVAIAPGALNGDKASVRSSPTLPERDLVPRPDSPAQQLKSPFQPVRD 461 GP PP+ P A NG K P + P P P Q+ S +D Sbjct: 1702 KGPQTKKSSATSPPICPDPSAKNGSKG--------PLSTVAPAPLLPVQKDSSKTAKGKD 1753 Query: 462 NSLAPQ 467 S +P+ Sbjct: 1754 ASHSPK 1759 Score = 49.7 bits (117), Expect = 6e-06 Identities = 63/234 (26%), Positives = 81/234 (34%), Gaps = 18/234 (7%) Query: 252 PHAPAAPSALARDQGSPLAAADVLKPQDSPLGLAKEAPEP-GSTRLLSPGAAA---GGLQ 307 P AP+ A SP P+ +P A P P G SP A Sbjct: 957 PSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTP 1016 Query: 308 GAPHGKPKIWSLAETATSPDGAPKASPPPPAGHPGAHGPSAGAPLQHPAFLPSHGLYTCH 367 +P G P + A++P P A+PP P G P A GAP A LPS Sbjct: 1017 PSPKGSPAATPFPKGASTP---PAATPPSPKGSPAATPLPKGAPTTPAATLPS------- 1066 Query: 368 IGKFSNWTNSAFLAQGSLLNMRSFLGVGAPHAAPHG-PHLPAPPPPQPPVAIAPGALNGD 426 K T S A G +P G P PA PP P +A G Sbjct: 1067 -PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGA 1125 Query: 427 KASVRSSPTLPERDLV--PRPDSPAQQLKSPFQPVRDNSLAPQEGTPRILAALP 478 + ++P P+ L P +P +P P + P +G P AA P Sbjct: 1126 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1179 Score = 46.2 bits (108), Expect = 7e-05 Identities = 71/242 (29%), Positives = 88/242 (36%), Gaps = 36/242 (14%) Query: 252 PHAPAAPSALARDQG-SPLAAADVLKPQDSPLG--LAKEAPEPGSTRLLSP--GAAAGGL 306 P +P+A +G S AA P+ SP L K AP + L SP G A L Sbjct: 1017 PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSL 1076 Query: 307 QGAPHGKPKIWSLAETATSPDGAPKASPPPPAGHPGAHGPSAGAPLQHPAFLPS--HGLY 364 +GAP P A+PP P G P P GAP+ A PS GL Sbjct: 1077 KGAPT-----------------PPAATPPSPKGGPATPSPK-GAPMPPAATPPSPKGGLA 1118 Query: 365 T-CHIGKFSNWTNSAFLAQGSLLNMRSFLGVGAPHAAPHGPH--LPAPPP---PQPPVAI 418 T H G + + +G L P A P P L PPP P P A Sbjct: 1119 TPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT 1178 Query: 419 APGALNG-DKASVRSSPTLPERDLVPRPDSPAQQLKSPFQPVRDNSLAPQEGTPRILAAL 477 P G S + +PT P P SP L +P + A +P+ A Sbjct: 1179 PPSPKGGLATPSPKGAPTTP----AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1234 Query: 478 PS 479 PS Sbjct: 1235 PS 1236 Score = 46.2 bits (108), Expect = 7e-05 Identities = 70/262 (26%), Positives = 91/262 (34%), Gaps = 37/262 (14%) Query: 249 AEAPHAPAAPSALARDQGSPLAAADVLKPQDSPLGLAKEAPEPG-STRLLSPGAAAGGLQ 307 A P +P A +G+P A P GLA +P+ +T +P + GGL Sbjct: 1153 AATPPSPKGGLATPPPKGAPTTPAAT--PPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1210 Query: 308 G-APHGKPKIWSLAETATSPDGA------------PKASPPPPAGHPGAHGPSAGAPLQH 354 +P G P + A T SP G P A+PP P G P A P GAP Sbjct: 1211 TPSPKGAPT--TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGP-ATPPPKGAPTPP 1267 Query: 355 PAFLPS--HGLYTC-HIGKFSNWTNSAFLAQGSLLNMRSFLGVGAPHAAPHGPH------ 405 A PS GL T H G + + +G P A P P Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP 1327 Query: 406 ----LPAPPPPQPPVAIAPGALNGDKASVRSSPTLPERDLVPRPDSPAQQLK-----SPF 456 P PP PP L S + PT P P P + K +P Sbjct: 1328 PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP 1387 Query: 457 QPVRDNSLAPQEGTPRILAALP 478 P R ++ +G P A +P Sbjct: 1388 SPKRGPAIPSPKGDPTSPAVIP 1409 Score = 45.1 bits (105), Expect = 1e-04 Identities = 65/231 (28%), Positives = 84/231 (36%), Gaps = 31/231 (13%) Query: 249 AEAPHAPAAPSALARDQGSPLA-AADVLKPQDSPLGLA-KEAPEPGSTRLLSPGAAAGGL 306 A P +P A +G+P AA P+ P K AP P + +P + GGL Sbjct: 1222 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAA---TPPSLKGGL 1278 Query: 307 QGAPH-GKPKIWSLAETATSPDGAPKASPP-----PPAGHPGAHGPSAGAPLQHPAFLPS 360 PH G P T SP G P SPP PPA P + S G P P P+ Sbjct: 1279 ATPPHKGAPN--PAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP--PPKGAPT 1334 Query: 361 HGLYTCHIGKFSNWTNSAF-LAQGSLLNMRSFLGVGAPHAAPHGPHLPAPPPPQPPVAIA 419 T K + + ++G S G P A P PA PP P A Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPA 1394 Query: 420 PGALNGDKASVRSSPTLPERDLVPRPDSPAQQLKSPFQPV-RDNSLAPQEG 469 + GD S P P+ K+P PV R+ + P +G Sbjct: 1395 IPSPKGDPTSPAVIPLSPK--------------KAPATPVTREGAATPSKG 1431 Score = 42.7 bits (99), Expect = 7e-04 Identities = 64/237 (27%), Positives = 78/237 (32%), Gaps = 44/237 (18%) Query: 249 AEAPHAPAAPSALARDQGSPLAAADVLKPQDSPLGLAKEAPEPGSTRLLSPGAAAGGLQG 308 A PH AP+ A SP P+ +P A P P P A Sbjct: 1118 ATPPHK-GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1176 Query: 309 APHGKPKIWSLAETATSPDGAPK---ASPPPPAGHPGAHGPSAGAPLQHPAFLPSHGLYT 365 A PK LA SP GAP A+PP P G P GAP A PS Sbjct: 1177 ATPPSPK-GGLA--TPSPKGAPTTPAATPPSPKGGLATPSPK-GAPTTPAATPPS----- 1227 Query: 366 CHIGKFSNWTNSAFLAQGSLLNMRSFLGVGAPHAAPHGPH-LPAPPPPQ---PPVAIAPG 421 +G L P A P P PA PPP+ P A P Sbjct: 1228 ---------------PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPP 1272 Query: 422 ALNGDKASVRSSPTLPERDLVPRPDSPAQQLKSPFQPVRDNSLAPQEGTPRILAALP 478 +L G A+ P +P + +P P + +P +G P AA P Sbjct: 1273 SLKGGLAT------------PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP 1317 Score = 39.7 bits (91), Expect = 0.006 Identities = 70/269 (26%), Positives = 95/269 (35%), Gaps = 54/269 (20%) Query: 241 SNEDDEDKAEAPHAPAAPSALARDQGSPL-AAADVLKPQDSPLGLAKEAPEPGSTRLLSP 299 S + +D H+P PS +G+P +A L P+ L KE P P L P Sbjct: 842 SFQGSKDSPATTHSPTPPSP----KGAPTPSAVTPLSPKGVTLP-PKETPTPSVVNL--P 894 Query: 300 GAAAGGLQGAPHGKPKIWSLAETATSPDGA--------------PKASPPPPAGHPGAHG 345 G AP P +L+ T++SP A PK +P PPA P + Sbjct: 895 FPKEGPATPAPKQAP---ALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPS-- 949 Query: 346 PSAGAPLQHPAFLPSHGLYTCHIGKFSNWTNSAFLAQGSLLNMRSFLGVGAPHAAPHGPH 405 P G P + P+ T K T S A P + GP Sbjct: 950 PKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP--------PAATPPSPKGGPA 1001 Query: 406 LPAPPPPQPPVAIAPGALNGDKASV-----RSSPTL---------PERDLVPR--PDSPA 449 P+P P A+ P + G A+ S+P P +P+ P +PA Sbjct: 1002 TPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPA 1061 Query: 450 QQLKSPFQPVRDNSLAPQEGTPRILAALP 478 L SP SL +G P AA P Sbjct: 1062 ATLPSPKGGPATPSL---KGAPTPPAATP 1087 Score = 33.5 bits (75), Expect = 0.44 Identities = 59/263 (22%), Positives = 80/263 (30%), Gaps = 72/263 (27%) Query: 257 APSALARDQGSPLAAADVLKPQDSPLGLAKEAPEPGSTRLL------------------- 297 AP+ A SP + P+ +P A P P T L Sbjct: 1309 APTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG 1368 Query: 298 -SPGAAAGGLQGAPHGKPKIWSLAETATSPDG----------APKASPPPPAGHPGAHGP 346 +P AA +G P P SP G +PK +P P GA P Sbjct: 1369 PTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATP 1428 Query: 347 SAGAPLQHPAFLPSHGLYTCHIGKFSNWTNSAFLAQGSLLNMRSFLGVGAPHAAPHGPH- 405 S G L PA P ++++ AP P P Sbjct: 1429 SKG-DLTPPAVTP--------------------------VSLKKAPATSAPKGGPATPSS 1461 Query: 406 -----LPAPPPPQPPVAIAPGALNGDKASVRSSPTLPERDLVPR-----PDSPAQQLKSP 455 LPA PP P AP + +S + +P P P P SP + +P Sbjct: 1462 KGDPTLPAVTPPSPKEPPAPKQV-ATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATP 1520 Query: 456 F---QPVRDNSLAPQEGTPRILA 475 P+ + + TP LA Sbjct: 1521 SSRRDPIAPTATLLSKKTPATLA 1543 Score = 33.1 bits (74), Expect = 0.57 Identities = 57/245 (23%), Positives = 87/245 (35%), Gaps = 34/245 (13%) Query: 253 HAPAAPSALARDQGSPLAAADVLKPQDSPLGLAKEAPEPGSTRLLSPGAAAGG---LQGA 309 + P APS ++ +PLA VL P+ + K P P L P G + G Sbjct: 707 NCPVAPSP--QNTCAPLATL-VLAPE-----IPKSVPSPS----LPPAGTPPGTKKVDGI 754 Query: 310 PH--------GKPKIWSLAETATSPDGAPKASPPPPAGHPGAHGPSAGAPLQHPAFLPSH 361 H PK ++ S + K + A P G S + P Sbjct: 755 SHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGS 814 Query: 362 GLYTCHIGKFSNWTN---SAFLAQGSLLNMRSFLGVGAPHAAPHGPHLPAPPPPQPPVAI 418 IG S+ + ++FL + SL SF G A H P P+P P A+ Sbjct: 815 AGPDTPIGNLSSPVSPVEASFLPENSL----SFQGSKDSPATTHSPTPPSPKGAPTPSAV 870 Query: 419 APGALNGDKASVRSSPTLPERDLVPRPDSPAQQLKSPFQPVRDNSLAPQEG----TPRIL 474 P + G + +PT +L + PA + S +P++ P+ + Sbjct: 871 TPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGI 930 Query: 475 AALPS 479 A PS Sbjct: 931 PASPS 935 >gi|40354216 sine oculis homeobox homolog 5 [Homo sapiens] Length = 739 Score = 54.3 bits (129), Expect = 2e-07 Identities = 66/235 (28%), Positives = 89/235 (37%), Gaps = 39/235 (16%) Query: 138 STSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARS 197 S + LKA +R N YPT EK LA +T ++LTQVS WF N RR + GA Sbjct: 212 SRAALKAC---YRGNRYPTPDEKRRLATLTGLSLTQVSNWFKN--RRQRDRTGAGGGAPC 266 Query: 198 KDQEDGALFGSDTEGDPEKAEDDEEIDLESIDIDKIDEHDGDQSNEDDEDKAEAPHAPAA 257 K + DG TE + ++ +D E + + + + P AP Sbjct: 267 KSESDG---NPTTEDESSRSPEDLERGAAPVSAEAAAQGSIFLA-------GTGPPAPCP 316 Query: 258 PSALARDQGSPLAAADVLKPQDSPLGLAKEAP------EPGSTRLLSPGAAAGGLQGAPH 311 S+ GS LAA+ SP L P G L P GG GAP Sbjct: 317 ASSSILVNGSFLAAS------GSPAVLLNGGPVIINGLALGEASSLGPLLLTGG-GGAPP 369 Query: 312 GKPKIWSLAETATS-----------PDGAPKASPPPPAGHPGAHGPSAGAPLQHP 355 +P +ET TS + A +P A GP+ G + P Sbjct: 370 PQPSPQGASETKTSLVLDPQTGEVRLEEAQSEAPETKGAQVAAPGPALGEEVLGP 424 >gi|85068580 homeobox B7 [Homo sapiens] Length = 217 Score = 53.5 bits (127), Expect = 4e-07 Identities = 62/234 (26%), Positives = 93/234 (39%), Gaps = 38/234 (16%) Query: 6 LGYPQYLSAAGPGAYGGERPGVLAAAAAAAAAASSGRPGAAELGGGAGAAAVTSVLGMYA 65 L Y L + P + G + A A++ RPG G G+GA+ S+ G+Y Sbjct: 4 LYYANTLFSKYPASSSVFATGAFPEQTSCAFASNPQRPG---YGAGSGASFAASMQGLYP 60 Query: 66 AAGPYAGAPNYSAFLP-YAADLSLFSQMGSQYELKDNPGVHP--------------ATFA 110 G AG + Y + S F+ + +E ++ GV P + A Sbjct: 61 GGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFE-QNLSGVCPGDSAKAAGAKEQRDSDLA 119 Query: 111 AHTAPAYYPYGQFQYGDPGRPKNA-TRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKM 169 A + YP+ + D R + TR T L+ E N Y T+ +I +A + Sbjct: 120 AESNFRIYPWMRSSGTDRKRGRQTYTRYQTLELE---KEFHYNRYLTRRRRIEIAHTLCL 176 Query: 170 TLTQVSTWFANARRRLKKENKVTWGARSKDQEDGALFGSDTEG-DPEKAEDDEE 222 T Q+ WF N R + KKENK G T G D +AE++EE Sbjct: 177 TERQIKIWFQNRRMKWKKENKTA--------------GPGTTGQDRAEAEEEEE 216 >gi|27502383 Meis homeobox 2 isoform h [Homo sapiens] Length = 306 Score = 53.1 bits (126), Expect = 5e-07 Identities = 25/66 (37%), Positives = 41/66 (62%), Gaps = 7/66 (10%) Query: 127 DPGRPKNATRE-------STSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFA 179 DP + K ++ +T+ ++AWL +H +PYP++ +K LA T +T+ QV+ WF Sbjct: 181 DPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFI 240 Query: 180 NARRRL 185 NARRR+ Sbjct: 241 NARRRI 246 >gi|27502381 Meis homeobox 2 isoform g [Homo sapiens] Length = 388 Score = 53.1 bits (126), Expect = 5e-07 Identities = 25/66 (37%), Positives = 41/66 (62%), Gaps = 7/66 (10%) Query: 127 DPGRPKNATRE-------STSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFA 179 DP + K ++ +T+ ++AWL +H +PYP++ +K LA T +T+ QV+ WF Sbjct: 256 DPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFI 315 Query: 180 NARRRL 185 NARRR+ Sbjct: 316 NARRRI 321 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.130 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,242,017 Number of Sequences: 37866 Number of extensions: 1639248 Number of successful extensions: 23355 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 436 Number of HSP's successfully gapped in prelim test: 1180 Number of HSP's that attempted gapping in prelim test: 13688 Number of HSP's gapped (non-prelim): 8306 length of query: 480 length of database: 18,247,518 effective HSP length: 106 effective length of query: 374 effective length of database: 14,233,722 effective search space: 5323412028 effective search space used: 5323412028 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.