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Search of human proteins with 51172610
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51172610 Rho guanine nucleotide exchange factor (GEF) 5-like
[Homo sapiens]
(484 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51172610 Rho guanine nucleotide exchange factor (GEF) 5-like ... 977 0.0
gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens] 961 0.0
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 74 3e-13
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 71 2e-12
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 63 5e-10
gi|44890059 involucrin [Homo sapiens] 57 4e-08
gi|148746195 trichohyalin [Homo sapiens] 56 8e-08
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 52 2e-06
gi|221139761 zinc finger protein 853 [Homo sapiens] 51 2e-06
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 50 4e-06
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 47 4e-05
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 47 4e-05
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 47 4e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 47 5e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 45 1e-04
gi|221316599 chromogranin B precursor [Homo sapiens] 45 1e-04
gi|119220598 apolipoprotein B48 receptor [Homo sapiens] 45 1e-04
gi|4504487 histidine rich calcium binding protein precursor [Hom... 44 3e-04
gi|157266264 pleckstrin homology-like domain, family B, member 3... 44 3e-04
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 44 3e-04
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 44 4e-04
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 44 4e-04
gi|224458301 family with sequence similarity 186, member A [Homo... 43 6e-04
gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap... 43 7e-04
gi|221219020 NYD-SP11 protein [Homo sapiens] 42 0.001
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 42 0.001
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 42 0.001
gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi... 42 0.001
gi|110347429 mediator complex subunit 12 [Homo sapiens] 42 0.001
gi|24415404 MDN1, midasin homolog [Homo sapiens] 42 0.001
>gi|51172610 Rho guanine nucleotide exchange factor (GEF) 5-like
[Homo sapiens]
Length = 484
Score = 977 bits (2526), Expect = 0.0
Identities = 484/484 (100%), Positives = 484/484 (100%)
Query: 1 MEAEEAQRGASPPISAIEEFSIIPEAPMRSSQVSALGLEAQEDEDPSYKWREEHRLSATQ 60
MEAEEAQRGASPPISAIEEFSIIPEAPMRSSQVSALGLEAQEDEDPSYKWREEHRLSATQ
Sbjct: 1 MEAEEAQRGASPPISAIEEFSIIPEAPMRSSQVSALGLEAQEDEDPSYKWREEHRLSATQ 60
Query: 61 QSELRDVCDYAIETMPSFPKEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQARTLA 120
QSELRDVCDYAIETMPSFPKEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQARTLA
Sbjct: 61 QSELRDVCDYAIETMPSFPKEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQARTLA 120
Query: 121 PPELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQT 180
PPELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQT
Sbjct: 121 PPELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQT 180
Query: 181 RYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGF 240
RYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGF
Sbjct: 181 RYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGF 240
Query: 241 RGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGL 300
RGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGL
Sbjct: 241 RGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGL 300
Query: 301 NDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQE 360
NDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQE
Sbjct: 301 NDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQE 360
Query: 361 DHGIKEKGVPVSGQEAKEPESWDGGRLGAVGRARSREEENEHHGPSMPALIAPEDSPHCD 420
DHGIKEKGVPVSGQEAKEPESWDGGRLGAVGRARSREEENEHHGPSMPALIAPEDSPHCD
Sbjct: 361 DHGIKEKGVPVSGQEAKEPESWDGGRLGAVGRARSREEENEHHGPSMPALIAPEDSPHCD 420
Query: 421 LFPGASYLVTQIPGTQTESRAEELSPAALSPLLEPIRCSHQPISLLGSFLTEESPDKEKL 480
LFPGASYLVTQIPGTQTESRAEELSPAALSPLLEPIRCSHQPISLLGSFLTEESPDKEKL
Sbjct: 421 LFPGASYLVTQIPGTQTESRAEELSPAALSPLLEPIRCSHQPISLLGSFLTEESPDKEKL 480
Query: 481 LSVL 484
LSVL
Sbjct: 481 LSVL 484
>gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]
Length = 1597
Score = 961 bits (2484), Expect = 0.0
Identities = 474/478 (99%), Positives = 476/478 (99%)
Query: 1 MEAEEAQRGASPPISAIEEFSIIPEAPMRSSQVSALGLEAQEDEDPSYKWREEHRLSATQ 60
MEAEEAQRGASPPISAIEEFSIIPEAPMRSSQVSALGLEAQEDEDPSYKWREEHRLSATQ
Sbjct: 1 MEAEEAQRGASPPISAIEEFSIIPEAPMRSSQVSALGLEAQEDEDPSYKWREEHRLSATQ 60
Query: 61 QSELRDVCDYAIETMPSFPKEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQARTLA 120
QSELRDVCDYAIETMPSFPKEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQARTLA
Sbjct: 61 QSELRDVCDYAIETMPSFPKEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQARTLA 120
Query: 121 PPELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQT 180
PPELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQT
Sbjct: 121 PPELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQT 180
Query: 181 RYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGF 240
RYYSPCEEHPAETNQNEG+ESGTIRQGEELP EELQESQGLLHPQEVQVLEEQGQQEAGF
Sbjct: 181 RYYSPCEEHPAETNQNEGSESGTIRQGEELPPEELQESQGLLHPQEVQVLEEQGQQEAGF 240
Query: 241 RGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGL 300
RGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGL
Sbjct: 241 RGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGL 300
Query: 301 NDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQE 360
NDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQE
Sbjct: 301 NDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQE 360
Query: 361 DHGIKEKGVPVSGQEAKEPESWDGGRLGAVGRARSREEENEHHGPSMPALIAPEDSPHCD 420
DHGIKEKGVPVSGQEAKEPESWDGGRLGAVGRARSREEENEHHGPSMPALIAPEDSPHCD
Sbjct: 361 DHGIKEKGVPVSGQEAKEPESWDGGRLGAVGRARSREEENEHHGPSMPALIAPEDSPHCD 420
Query: 421 LFPGASYLVTQIPGTQTESRAEELSPAALSPLLEPIRCSHQPISLLGSFLTEESPDKE 478
LFPGASYL+TQIPGTQTESRAEELSPAALSP LEPIRCSHQPISLLGSFLTEESPDKE
Sbjct: 421 LFPGASYLMTQIPGTQTESRAEELSPAALSPSLEPIRCSHQPISLLGSFLTEESPDKE 478
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 73.9 bits (180), Expect = 3e-13
Identities = 79/262 (30%), Positives = 117/262 (44%), Gaps = 35/262 (13%)
Query: 162 GSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQESQGL 221
G G+ EEEEE EE E + EG E +GEE E E +G
Sbjct: 822 GKGEREEEEEEGEGEE---------EEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEG- 871
Query: 222 LHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQD 281
E + EE+G+ E GEG E+ +G GEE+ + +E+GE K ++E +
Sbjct: 872 -EEGEGEGEEEEGEGEGEEEGEGEGEEEE-GEGE-GEEEGEGEGEEEEGEGKGEEEGEEG 928
Query: 282 VMLGRQ--GERMGLTGEPEGLND-GEWEQEDMERKAQGQG--------GPEQGEERKREL 330
G + GE G GE EG + GEWE E+ E + +G+ G +GEE + E
Sbjct: 929 EGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEG 988
Query: 331 QVPEENRADSQDEKSQTFLGKSE-EVTGKQEDHGIKE---KGVPVSGQEAKEPESWDGGR 386
+ EE + +E+ + G+ E E G++E+ G E +G G+ +E +G
Sbjct: 989 EGEEEEGEEEGEEEGE---GEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEE 1045
Query: 387 LGAVGRA----RSREEENEHHG 404
G R+REEE E G
Sbjct: 1046 REKEGEGEENRRNREEEEEEEG 1067
Score = 72.4 bits (176), Expect = 9e-13
Identities = 70/242 (28%), Positives = 112/242 (46%), Gaps = 13/242 (5%)
Query: 167 EEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQESQGLLHPQE 226
+E EE + G+ E E + EG E G +GEE+ E +E +G +E
Sbjct: 725 QEMEEGGEEEHGEGEEEEGDREEEEE-KEGEGKEEG---EGEEVEGEREKE-EGERKKEE 779
Query: 227 VQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIE--QVNDEKGEQKQKQEQVQ-DVM 283
EE+G++E G +GEG E E +E +V + KGE+++++E+ + +
Sbjct: 780 RAGKEEKGEEE-GDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEE 838
Query: 284 LGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDE 343
G E G E EG GE E E+ E + +G+ G +GEE + E + EE + ++E
Sbjct: 839 EGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEE 898
Query: 344 KSQTFLGKSEEV-TGKQEDHGIKEKGVPVSGQEAKEPESWDGGRLGAVGRARSREEENEH 402
+ + G+ EE G+ E+ + KG + E E +G G G EEE E
Sbjct: 899 EGE---GEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEW 955
Query: 403 HG 404
G
Sbjct: 956 EG 957
Score = 72.0 bits (175), Expect = 1e-12
Identities = 69/268 (25%), Positives = 119/268 (44%), Gaps = 14/268 (5%)
Query: 144 GSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGT 203
G EEE E G G + E EE + G+ E E + EG E
Sbjct: 824 GEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEG 883
Query: 204 IRQGEELPSEELQESQGLLHPQEV---QVLEEQGQ---QEAGFRGEGTLREDVC-ADGLL 256
+GEE E +E +G +E + EE+G+ +E G GEG E+ +G
Sbjct: 884 EGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGED 943
Query: 257 GEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEG-LNDGEWEQEDMERKAQ 315
GE + E+ + +GE+++ + + ++ +GE G GE EG +GE E E+ E + +
Sbjct: 944 GEGEGEEEEGEWEGEEEEGEGEGEE-----EGEGEGEEGEGEGEEEEGEGEGEEEEGEEE 998
Query: 316 GQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQE 375
G+ E EE + E + EE + + E + G+ EE G++E +++G +
Sbjct: 999 GEEEGEGEEEGEGEGEEEEEGEVEGEVE-GEEGEGEGEEEEGEEEGEEREKEGEGEENRR 1057
Query: 376 AKEPESWDGGRLGAVGRARSREEENEHH 403
+E E + G+ G + ++ E +
Sbjct: 1058 NREEEEEEEGKYQETGEEENERQDGEEY 1085
Score = 71.2 bits (173), Expect = 2e-12
Identities = 102/420 (24%), Positives = 163/420 (38%), Gaps = 45/420 (10%)
Query: 13 PISAIEEFSI----IPEAPMRSSQVSALGLEAQEDEDPSYKWREEHRLSATQQSELRDVC 68
P + IE FS IPE + G+E QE E + + D+
Sbjct: 572 PATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLT 631
Query: 69 DYAIETMPSFPKEGSADVEPNQ--ESLVAEACDTPEHWEAVPQSLA------------GR 114
D A + G A+ P + E EHW+ + G
Sbjct: 632 DKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGE 691
Query: 115 QARTLAPPELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEE-EEETS 173
+ LA E W + + + + G ++E + G G+ EE + E
Sbjct: 692 GEKELAEKEEWK---KRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEE 748
Query: 174 SDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQESQGLLHPQEV----QV 229
+ G+ + EE E + EG R G+E EE + QG +E +
Sbjct: 749 EEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEE-EGDQGEGEEEETEGRGEE 807
Query: 230 LEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGE 289
EE G+ E G EG + + GEE+ E +E+GE ++++ + + G +GE
Sbjct: 808 KEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEG-EEEEGEGEEEEGEGKGEEEGEEGE 866
Query: 290 RMGLTGEPEGLNDGEWEQEDMERKAQG-QGGPEQGEERKRELQVPEENRADSQDEKSQTF 348
GE EG +GE E E+ E + +G + G +GEE + E + EE + ++E+ +
Sbjct: 867 -----GEEEG-EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE-- 918
Query: 349 LGKSEEVTGKQEDHGIKE----KGVPVSGQEAKEPESWDGGRLGAVGRARSREEENEHHG 404
GK EE + E G +E +G G+ +E W+G G EEE E G
Sbjct: 919 -GKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEG---EEEGEGEG 974
Score = 69.7 bits (169), Expect = 6e-12
Identities = 70/247 (28%), Positives = 111/247 (44%), Gaps = 27/247 (10%)
Query: 144 GSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAE-TNQNEGAESG 202
G EEE E G G G+ EEEE + G+ EE E + EG G
Sbjct: 856 GKGEEEGEEGEGEEEGEEGEGEGEEEE---GEGEGEEEGEGEGEEEEGEGEGEEEGEGEG 912
Query: 203 TIRQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMI 262
+GE EE +E +G E + E +G+ E G GEG E GEE+
Sbjct: 913 EEEEGEGKGEEEGEEGEG-----EGEEEEGEGEGEDG-EGEGEEEEGEWE----GEEEEG 962
Query: 263 EQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQE-----------DME 311
E +E+GE + ++ + + +GE GE EG +GE E+E ++E
Sbjct: 963 EGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVE 1022
Query: 312 RKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPV 371
+ +G+ G +GEE + E + EE + + E+++ + EE GK ++ G +E+
Sbjct: 1023 GEVEGEEGEGEGEEEEGE-EEGEEREKEGEGEENRRNREEEEEEEGKYQETG-EEENERQ 1080
Query: 372 SGQEAKE 378
G+E K+
Sbjct: 1081 DGEEYKK 1087
Score = 68.6 bits (166), Expect = 1e-11
Identities = 74/270 (27%), Positives = 116/270 (42%), Gaps = 35/270 (12%)
Query: 163 SGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAE--SGTIRQGEELPSEELQESQG 220
+G+ E+ EE G+ E E + EG E G + EE E +E +G
Sbjct: 781 AGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEG 840
Query: 221 LLHPQEVQVLEEQGQ------------QEAGFRGEGTLREDVC-------ADGLLGEEQM 261
+E + EE+G+ +E G GEG E+ +G GEE+
Sbjct: 841 EGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEG-EGEEEE 899
Query: 262 IEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEG-LNDGEWEQEDMERKAQGQGGP 320
E +E+GE + ++E+ + +GE G GE EG +GE E ED E + + + G
Sbjct: 900 GEGEGEEEGEGEGEEEEGEG-----KGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGE 954
Query: 321 EQGEERKRELQVPEENRADSQ------DEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQ 374
+GEE + E + EE + + +E+ G+ EE + E+ G E+ G+
Sbjct: 955 WEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGE 1014
Query: 375 EAKEPESWDGGRLGAVGRARSREEENEHHG 404
E +E E +G G G EEE E G
Sbjct: 1015 EEEEGEV-EGEVEGEEGEGEGEEEEGEEEG 1043
Score = 55.1 bits (131), Expect = 1e-07
Identities = 63/238 (26%), Positives = 99/238 (41%), Gaps = 19/238 (7%)
Query: 144 GSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGT 203
G EEE E G G G+ EEE E + E+ E + EG G
Sbjct: 902 GEGEEEGE---GEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGE 958
Query: 204 IRQGEELPSEELQ------ESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLG 257
+GE EE + E +G E + EE+G++E GEG E+ +G
Sbjct: 959 EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEG--EEEGEGEGEEE 1016
Query: 258 EEQMIE-QVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQG 316
EE +E +V E+GE + ++E+ ++ +GE GE E E+E+ E K Q
Sbjct: 1017 EEGEVEGEVEGEEGEGEGEEEEGEE-----EGEEREKEGEGEENRRNREEEEEEEGKYQE 1071
Query: 317 QGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQ 374
G E + E + + + + K +T+ KS VT Q + + +PV +
Sbjct: 1072 TGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKS--VTNTQGNGKEQRSKMPVQSK 1127
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 71.2 bits (173), Expect = 2e-12
Identities = 68/229 (29%), Positives = 113/229 (49%), Gaps = 32/229 (13%)
Query: 164 GQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGA---ESGTIRQGEELPSEE---LQE 217
GQ E+E + GQ R E + + EG + G +R+ E E+ ++E
Sbjct: 101 GQVREQEGQVREQEGQVR------EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 154
Query: 218 SQGLLHPQEVQVLEEQGQ---QEAGFRG-EGTLREDVCADGLLGEE--QMIEQVNDEKGE 271
+G + QE QV E++GQ QE R EG +RE +G +GE+ QM EQ ++ GE
Sbjct: 155 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ---EGQMGEQEGQMGEQ-EEQMGE 210
Query: 272 QKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQ 331
Q++ Q Q Q+ +G Q E+M E G EQE+ +K + Q ++ + RK+E Q
Sbjct: 211 QEE-QMQKQEEQMGEQEEQMRKQEEQMG------EQEEQVQKQEEQVQKQEEQMRKQEEQ 263
Query: 332 VPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKEPE 380
+ E+ + E+ K +E T ++E G +E+ + ++ +E E
Sbjct: 264 MREQEEQMREQEEQML---KQKEQTEQEEQTGEQEEQMREQEEQMREQE 309
Score = 53.5 bits (127), Expect = 4e-07
Identities = 48/211 (22%), Positives = 99/211 (46%), Gaps = 16/211 (7%)
Query: 164 GQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGA---ESGTIRQGEELPSEE---LQE 217
GQ E+E + GQ R E + + EG + G +R+ E E+ + E
Sbjct: 143 GQVREQEGQVREQEGQVR------EQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGE 196
Query: 218 SQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCA-DGLLGEEQMIEQVNDEKGEQKQKQ 276
+G + QE Q+ E++ Q + G E + + +GE++ Q +E+ +++++Q
Sbjct: 197 QEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQ 256
Query: 277 EQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEEN 336
+ Q+ + Q E+M E + EQE+ + + Q ++ + R++E Q+ E+
Sbjct: 257 MRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQ- 315
Query: 337 RADSQDEKSQTFLGKSEEVTGKQEDHGIKEK 367
+ Q + + +GK EE +Q++ ++K
Sbjct: 316 --EEQMREQEEQMGKQEEQMWEQKEQMWEQK 344
Score = 50.1 bits (118), Expect = 5e-06
Identities = 58/264 (21%), Positives = 114/264 (43%), Gaps = 54/264 (20%)
Query: 129 IQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSG-QTRYYSPCE 187
++ + M +G +EE++ G+ EE+ + + G Q E
Sbjct: 187 VREQEGQMGEQEGQMGEQEEQM-------------GEQEEQMQKQEEQMGEQEEQMRKQE 233
Query: 188 EHPAETNQNEGAESGTIRQGEEL---PSEELQESQGLLHPQEVQVL---EEQGQQEAGFR 241
E E + + +++ EE E+++E + + QE Q+L E+ Q+E
Sbjct: 234 EQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGE 293
Query: 242 GEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLN 301
E +RE EEQM EQ +E+ ++++Q + Q+ +G+Q E+M E
Sbjct: 294 QEEQMREQ--------EEQMREQ--EEQMREQEEQMREQEEQMGKQEEQMWEQKEQM--- 340
Query: 302 DGEWEQEDMERKAQGQGGPEQGEERKRELQV---------------PEENRADSQDEK-- 344
WEQ++ K + Q G ++ + +K+E QV +E + Q+E+
Sbjct: 341 ---WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMG 397
Query: 345 -SQTFLGKSEEVTGKQEDHGIKEK 367
+ +G+ +E +QE+ ++K
Sbjct: 398 EQKEQMGEQKEQMREQEEQMGEQK 421
Score = 43.9 bits (102), Expect = 3e-04
Identities = 53/205 (25%), Positives = 99/205 (48%), Gaps = 22/205 (10%)
Query: 196 NEGAESGTIRQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGL 255
NE + EEL E ++S+ LH +E++ E + EG +RE +G
Sbjct: 6 NEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLET--DKIPLPQEGQVREQ---EGQ 60
Query: 256 LGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQ 315
+ E++ QV +++G+ ++++ QV+ E+ G E EG EQE R+ +
Sbjct: 61 VREQE--GQVREQEGQVREQEGQVR--------EQEGQVREQEGQVR---EQEGQVREQE 107
Query: 316 GQGGPEQGEERKRELQVPE-ENRADSQDEKSQTFLGKSEEVTG--KQEDHGIKEKGVPVS 372
GQ ++G+ R++E QV E E + Q+ + + G+ E G ++++ ++E+ V
Sbjct: 108 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 167
Query: 373 GQEAKEPESWDGGRLGAVGRARSRE 397
QE + E +G G+ R +E
Sbjct: 168 EQEGQVREQ-EGQVREQEGQVREQE 191
Score = 42.7 bits (99), Expect = 7e-04
Identities = 45/185 (24%), Positives = 87/185 (47%), Gaps = 25/185 (13%)
Query: 165 QAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEEL---PSEELQESQGL 221
Q E+EE QT EE E + + +R+ EE E+++E +
Sbjct: 270 QMREQEEQMLKQKEQTEQ----EEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQ 325
Query: 222 LHPQEVQVLEEQGQ----QEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQE 277
+ QE Q+ E++ Q +E ++ E + E EEQM +Q +E+ ++++Q
Sbjct: 326 MGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQ--------EEQMQKQ--EEQVRKQEEQM 375
Query: 278 QVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENR 337
+ Q+ + +Q E+M E GE +++ E+K Q + EQ E+K +++ EE+
Sbjct: 376 RKQEEQMRKQEEQMRKQEE----QMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHM 431
Query: 338 ADSQD 342
+ ++
Sbjct: 432 GEQKE 436
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 63.2 bits (152), Expect = 5e-10
Identities = 101/435 (23%), Positives = 165/435 (37%), Gaps = 57/435 (13%)
Query: 2 EAEEAQRGASPPISAIEEFSIIPEAPMRSSQVSALGLEAQEDEDPSYKWREEHRLSATQQ 61
EA EA++ A P ++E E S G EAQE E+ + +E +
Sbjct: 1907 EAPEAEKEAQPETESVEALETEGEDEPESE-----GAEAQEAEEAA----QEAEGQTQPE 1957
Query: 62 SELRDVCDYAIETMPSFPKEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQARTLAP 121
SE+ + + E P + +VE + EA E EA ++A A
Sbjct: 1958 SEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQ 2017
Query: 122 PELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAE-------EEEETSS 174
PE S+ ++ P S G E +EVE G T T G Q E E EE +
Sbjct: 2018 PE-------SDGVEAQPKSE--GEEAQEVE---GETQKTEGDAQPESDGVEAPEAEEEAQ 2065
Query: 175 DNSGQTRYYSPCEEHPAETN------------QNEGAESGTIRQGEELPSE--ELQESQG 220
+ G+ + + E HP + ++EG E+ +GE +E E E++G
Sbjct: 2066 EAEGEVQ-EAEGEAHPESEDVDAQEAEGEAQPESEGVEAPE-AEGEAQKAEGIEAPETEG 2123
Query: 221 LLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQ 280
P+ + + + EA EG +D + E + Q +E+ + + + +
Sbjct: 2124 EAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAP 2183
Query: 281 DVMLGRQGERMGLTG-EPEGLNDGEWE-QEDMERKAQGQGGPEQGEERKRELQVPEENRA 338
+ Q E G+ E EG E E E E + + Q PE E + E + E+
Sbjct: 2184 EAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEG 2243
Query: 339 DSQDEKS---QTFLGKSEEVTGKQEDHGIKE-KGVPVSGQEAKEPESWDGGRLG------ 388
++Q EK Q LG + + + E + P P G + G
Sbjct: 2244 ETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSRA 2303
Query: 389 -AVGRARSREEENEH 402
+ G ++ EN+H
Sbjct: 2304 SSWGNCWQKDSENDH 2318
Score = 56.6 bits (135), Expect = 5e-08
Identities = 87/373 (23%), Positives = 144/373 (38%), Gaps = 54/373 (14%)
Query: 85 DVEPNQESLVAEACDTPE-HWEAVPQSLA---------GRQARTLAPPELWACPIQSEHL 134
D +P Q AE + PE EA P+S ++A A PE
Sbjct: 1823 DQDPGQSD-GAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEG 1881
Query: 135 DMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETN 194
+ P S D+ + E E E P + E + ET S + +T E AE
Sbjct: 1882 EAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQ 1941
Query: 195 QNEGAESGTIRQGEELPSEELQESQGL----------LHPQEVQVLEEQGQQEAGFRGEG 244
+ E E+ +G+ P E+ ESQ + EV+V ++ + EA E
Sbjct: 1942 EAE--EAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESED 1999
Query: 245 TLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDG- 303
+ + EE+ + + + + K + E+ Q+V +GE G+ + +DG
Sbjct: 2000 VEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEV----EGETQKTEGDAQPESDGV 2055
Query: 304 ---EWEQEDME-----RKAQGQGGPEQGE--------ERKRELQVPEENRADSQDEKSQT 347
E E+E E ++A+G+ PE + E + E + E A+ + +K++
Sbjct: 2056 EAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEG 2115
Query: 348 FLGKSEEVTGKQEDHGIKEKGVPVSGQEAKEPESWDGGRLGAVGRAR------SREEENE 401
E + E GI+ P + EA +PES A G A+ +E E
Sbjct: 2116 IEAPETEGEAQPESEGIE---APEAEGEA-QPESEGVEAQDAEGEAQPESEGIEAQEAEE 2171
Query: 402 HHGPSMPALIAPE 414
P + + APE
Sbjct: 2172 EAQPELEGVEAPE 2184
Score = 42.7 bits (99), Expect = 7e-04
Identities = 77/293 (26%), Positives = 116/293 (39%), Gaps = 61/293 (20%)
Query: 123 ELW-ACPIQSEHLDMAPFS-------SDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSS 174
+LW C + + LD + DLGS F P T SG + SS
Sbjct: 1156 DLWPGCDVGEDQLDSGLWELTWSQALPDLGSHAMTENFTP-----TSSSGV-----DISS 1205
Query: 175 DNSGQTRYYSPCEEHPAETNQNEGAESGT-IRQGEELP---SEELQESQGLLHPQEVQVL 230
+ G PC A GT + QG ELP S + +S+ P +++
Sbjct: 1206 GSGGSGESSVPC------------AMDGTLVTQGTELPLKTSNQRPDSRTYESPGDLE-- 1251
Query: 231 EEQGQQEAGFRGEGTLREDVCADG-----LLGEEQMIEQVNDEKGEQKQKQE-QVQDVML 284
QQ+ F R CA EEQ ++ E ++E Q+++
Sbjct: 1252 ---NQQQCCFPTFLNARACACATNEDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKE 1308
Query: 285 GRQGERMGLTGEPEGLNDGEWE---QED---MERKAQGQGGPEQGEERKRELQVPEENRA 338
G +GE GL E L + + E QE+ +E + +G +Q EE + E ++ E
Sbjct: 1309 GTEGE--GLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLE-EIEETGGE 1365
Query: 339 DSQDEKSQ---TFLGKSEEVTGKQEDHGIKEKGVP----VSGQEAKEPESWDG 384
Q+E Q G + G+ + G+KE+G+P V GQE E S DG
Sbjct: 1366 GLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDG 1418
Score = 40.0 bits (92), Expect = 0.005
Identities = 79/370 (21%), Positives = 127/370 (34%), Gaps = 68/370 (18%)
Query: 109 QSLAGRQAR-TLAPP------ELWACPIQSEHL-----DMAPFSS---DLGSEEEEVEFW 153
Q L GR R L PP EL Q H +++ FS LG +E
Sbjct: 1577 QKLQGRAGRMVLEPPREALTGELLLQTQQRRHRLRGLRNLSAFSERTLGLGPLSFTLEDE 1636
Query: 154 PGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEE------HPAETNQNEGAESGTIRQ- 206
P L S LGS EE E + PCE P GA G I++
Sbjct: 1637 PAL-STALGSQLGEEAEGEE---------FCPCEACVRKKVSPMSPKATMGATRGPIKEA 1686
Query: 207 -----------GEELPSEELQESQGLLHPQEVQVLEEQGQQ-------------EAGFRG 242
GE E + + G H QG + + G G
Sbjct: 1687 FDLQQILQRKRGEHTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLGPGLSQGPGVDEGEDG 1746
Query: 243 EGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLND 302
EG+ R + D LGE + + +G+ + + + E G++ E
Sbjct: 1747 EGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQ 1806
Query: 303 GEWEQEDMERKAQGQGGPEQGEERKRE-LQVPE---ENRADSQDEKSQTFLGKSEEVTGK 358
G +++++ +A G + G+ E ++ PE E + +S+ ++ G ++E G+
Sbjct: 1807 GSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGE 1866
Query: 359 QEDHGIKEKGVPVSGQEAKEPE-------SWDGGRLGAVGRARSREEENEHHGPSMPAL- 410
+ + G+ E E W+ A E+E + S+ AL
Sbjct: 1867 AQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALE 1926
Query: 411 IAPEDSPHCD 420
ED P +
Sbjct: 1927 TEGEDEPESE 1936
Score = 38.5 bits (88), Expect = 0.014
Identities = 54/194 (27%), Positives = 78/194 (40%), Gaps = 28/194 (14%)
Query: 1 MEAEEAQRGASPPISAIEEFSIIPEAPMRSSQVSALGLEAQEDEDPSYKWRE-----EHR 55
++A+EA+ A P +E PEA + + A G+EA E E + E E
Sbjct: 2085 VDAQEAEGEAQPESEGVEA----PEAEGEAQK--AEGIEAPETEGEAQPESEGIEAPEAE 2138
Query: 56 LSATQQSELRDVCDYAIETMPSFPKEGSADVEPNQESLVA-EACDTPE-HWEAVPQS--L 111
A +SE + D E P EG E +E+ E + PE EA P+S +
Sbjct: 2139 GEAQPESEGVEAQDAEGEAQPE--SEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGI 2196
Query: 112 AGRQARTLAPPELWACPIQSEHLDMAPFSSDLGSEEEEVEFWP-----------GLTSLT 160
+A A PEL + P + + E E E P G ++
Sbjct: 2197 EAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVS 2256
Query: 161 LGSGQAEEEEETSS 174
LG GQ+EE E+SS
Sbjct: 2257 LGDGQSEEASESSS 2270
Score = 37.7 bits (86), Expect = 0.024
Identities = 56/233 (24%), Positives = 85/233 (36%), Gaps = 49/233 (21%)
Query: 165 QAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAE-------SGTIRQGEELPSEELQE 217
Q EE +E + Q E E Q EG + G +Q EE EE++E
Sbjct: 1302 QLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEE 1361
Query: 218 SQGL-LHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGE----EQMIEQVNDEKGEQ 272
+ G L + VQ+ E + E G +GE L E + +GL E Q + + + G+
Sbjct: 1362 TGGEGLQEEGVQLEEVKEGPEGGLQGE-ALEEGLKEEGLPEEGSVHGQELSEASSPDGKG 1420
Query: 273 KQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQV 332
Q+ + VQ+ GR A + P +G E E
Sbjct: 1421 SQEDDPVQEEEAGR-------------------------ASASAEPCPAEGTEEPTE--- 1452
Query: 333 PEENRADSQDEKSQTFLGKSEEVTGKQEDHGI-KEKGVPVSGQEAKEPESWDG 384
S+T SE +G Q + G+ K G + GQE + + G
Sbjct: 1453 -------PPSHLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQPTQG 1498
>gi|44890059 involucrin [Homo sapiens]
Length = 585
Score = 57.0 bits (136), Expect = 4e-08
Identities = 59/236 (25%), Positives = 105/236 (44%), Gaps = 31/236 (13%)
Query: 165 QAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGA------ESGTIRQGEELPS--EELQ 216
Q E++ E GQ ++ E P Q EG + G ++ E+ E L+
Sbjct: 298 QQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLE 357
Query: 217 ESQGLLHPQEVQVLE------EQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKG 270
+G L E QVL+ +QGQ + EG L+ L+ +E ++ + ++G
Sbjct: 358 HQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKH------LVQQEGQLKHLVQQEG 411
Query: 271 EQKQKQEQVQDVMLGRQGERMGLTGEPEG-LNDGEWEQEDMERKAQGQGGPEQGEERKRE 329
+ +Q++ QV+ L +Q ++ E EG L E +Q +E Q G P+ E+ +++
Sbjct: 412 QLEQQERQVEH--LEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQ 469
Query: 330 LQVPEENRADSQD-EKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKEPESWDG 384
L++PE+ + EK + L E+ G+ + +EK + PE DG
Sbjct: 470 LELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEK-------HLEHPEQQDG 518
Score = 45.4 bits (106), Expect = 1e-04
Identities = 55/224 (24%), Positives = 94/224 (41%), Gaps = 20/224 (8%)
Query: 165 QAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQESQGLLHP 224
Q E + E GQ E Q EG +Q +L E QE Q L
Sbjct: 178 QQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQ 237
Query: 225 QEVQVLE----EQGQQEAGFRGEGTLREDVCADGLLG--EEQM--IEQVNDEKGE----- 271
Q+ LE ++GQ E + EG L+ +G L EEQM ++ + ++G+
Sbjct: 238 QQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLD 297
Query: 272 QKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERK-------AQGQGGPEQGE 324
Q++KQ ++ + +G+ G+P+ L E + E +E + Q +G E E
Sbjct: 298 QQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLE 357
Query: 325 ERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKG 368
++ +L +PE+ + + Q K E Q H ++++G
Sbjct: 358 HQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEG 401
Score = 40.8 bits (94), Expect = 0.003
Identities = 39/181 (21%), Positives = 87/181 (48%), Gaps = 14/181 (7%)
Query: 185 PCE----EHPAETNQNEGAESGTIRQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGF 240
PC+ E P E + + T +G LP +E ++ Q PQE ++ ++ +Q +
Sbjct: 43 PCQKVPVELPVEVPSKQEEKHMTAVKG--LPEQECEQQQK--EPQEQELQQQHWEQHEEY 98
Query: 241 RGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGL 300
+ + + + + Q +Q+N + E+K+ +Q D L ++ E++G+ E + L
Sbjct: 99 QKAENPEQQLKQE----KTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKE-QLL 153
Query: 301 NDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQ-DEKSQTFLGKSEEVTGKQ 359
E ++ ++ Q +G + E+++ +L++PE+ + E+ + L E+ G+
Sbjct: 154 ELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQL 213
Query: 360 E 360
E
Sbjct: 214 E 214
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 55.8 bits (133), Expect = 8e-08
Identities = 48/191 (25%), Positives = 84/191 (43%), Gaps = 16/191 (8%)
Query: 165 QAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSEE-LQESQGLLH 223
Q E+E + + E Q E +R+ ++L E+ L+ Q L
Sbjct: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRR 397
Query: 224 PQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVM 283
Q+++ E+Q ++E R E LR E+Q+ + +E+ EQK +QE+ + +
Sbjct: 398 EQQLR-REQQLRREQQLRREQQLRR---------EQQLRREQEEERHEQKHEQERREQRL 447
Query: 284 LGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDE 343
Q ER E E E+ + ER+ Q ++ E R+R L++ EE R + Q+
Sbjct: 448 KREQEERRDWLKREE-----ETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQER 502
Query: 344 KSQTFLGKSEE 354
+ Q + EE
Sbjct: 503 REQQLRREQEE 513
Score = 48.1 bits (113), Expect = 2e-05
Identities = 48/223 (21%), Positives = 95/223 (42%), Gaps = 8/223 (3%)
Query: 146 EEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIR 205
EEE E W L + E E+ R E + + E +R
Sbjct: 481 EEERRERWLKLE-------EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
Query: 206 QGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQV 265
++L E+ + + LL +E + LE++ +++ R + R+ + +Q +++
Sbjct: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
Query: 266 NDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGE-WEQEDMERKAQGQGGPEQGE 324
+E+ EQ+ K+E+V+ + + E+ EPE + + E+ E + Q Q EQ E
Sbjct: 594 QEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQE 653
Query: 325 ERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEK 367
R++ L+ EE Q K + + E+ ++E +E+
Sbjct: 654 RREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARER 696
Score = 44.3 bits (103), Expect = 3e-04
Identities = 60/263 (22%), Positives = 111/263 (42%), Gaps = 18/263 (6%)
Query: 143 LGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESG 202
L E+EE W T Q +++ D + R E Q E E
Sbjct: 447 LKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506
Query: 203 TIRQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMI 262
R+ EE + L+ + Q+ E+Q ++E R E L+ + EE+ +
Sbjct: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKRE--------EEKRL 558
Query: 263 EQVNDEKGEQKQKQEQVQDVMLGRQGER--MGLTGEPEGLNDGEWEQEDMERKAQGQGGP 320
EQ E+ K++QE+ +D +L R+ ER L E E + ++E++ER Q +
Sbjct: 559 EQERREQ-RLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERRE 617
Query: 321 ------EQGEERKRELQVPEENRADSQDE-KSQTFLGKSEEVTGKQEDHGIKEKGVPVSG 373
E EER+++L EE Q + + + + + + ++E+ ++++
Sbjct: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHE 677
Query: 374 QEAKEPESWDGGRLGAVGRARSR 396
+E +E E + + A R +SR
Sbjct: 678 EERREQELAEEEQEQARERIKSR 700
Score = 44.3 bits (103), Expect = 3e-04
Identities = 58/249 (23%), Positives = 109/249 (43%), Gaps = 22/249 (8%)
Query: 165 QAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQESQGLLHP 224
Q EE + R Y EE E Q G E T R+ +EL + +E + L
Sbjct: 1032 QLLREEREKRRLQERERQYREEEELQQEEEQLLGEERET-RRRQELERQYRKEEE--LQQ 1088
Query: 225 QEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVML 284
+E Q+L E+ ++ E RE+ + L EE+ + + EK +++ + Q ++
Sbjct: 1089 EEEQLLREEPEKRRRQERERQCREE---EELQQEEEQLLREEREKRRRQELERQYREEEE 1145
Query: 285 GRQGERMGLTGEPEGLNDGEW-----EQEDMERKAQGQGGPEQGEER-KRELQVPEENRA 338
+Q E L EPE E E+E+++++ + EQ + R +RE Q EE
Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEEL 1205
Query: 339 DSQDEKSQTFLGKSEEVTGK-----QEDHGIKEKGVPVSGQEAKEPESWDGGRLGAVGRA 393
Q K Q + + + K ++++ +++ V G+E ++ + +L R
Sbjct: 1206 QRQKRK-QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQL----RD 1260
Query: 394 RSREEENEH 402
R +++ +H
Sbjct: 1261 RQSQQDLQH 1269
Score = 43.1 bits (100), Expect = 6e-04
Identities = 53/244 (21%), Positives = 105/244 (43%), Gaps = 13/244 (5%)
Query: 144 GSEEEEVEFWPGLTSLTLGSGQAEEE------EETSSDNSGQTRYYSPCEEHPAETNQNE 197
G +EE+ G SL Q E++ + + GQ R E+ E E
Sbjct: 94 GLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQ---ERELAE 150
Query: 198 GAESGTIRQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGFRG-EGTLREDVCADGLL 256
G E ++ E + ++ + QE Q EE+ +E + +G E+ + L
Sbjct: 151 GEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQL 210
Query: 257 GEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQG 316
+++E + E++Q++ + QD + + E+ E + E QE+ + Q
Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEE---EPQR 267
Query: 317 QGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEA 376
Q ++ EE+ R+L+ E R ++E+ Q L + +++ KQE+ +++ QE
Sbjct: 268 QRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER 327
Query: 377 KEPE 380
+E +
Sbjct: 328 REQQ 331
Score = 43.1 bits (100), Expect = 6e-04
Identities = 46/204 (22%), Positives = 90/204 (44%), Gaps = 20/204 (9%)
Query: 167 EEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQESQGLLHPQE 226
E EE + + Q+ EE P E R+G E ++ +E Q + +E
Sbjct: 182 EREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEE 241
Query: 227 VQ--------VL--EEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQ 276
+ VL EE+ QE + + L+E+ EEQ+ + E ++Q++
Sbjct: 242 EEKEWRKRETVLRKEEEKLQEEEPQRQRELQEE--------EEQLRKLERQELRRERQEE 293
Query: 277 EQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEEN 336
EQ Q + R+ +++ E E E +E ER+ Q + EQ R++E + ++
Sbjct: 294 EQQQQRL--RREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQL 351
Query: 337 RADSQDEKSQTFLGKSEEVTGKQE 360
R + ++E+ + L + +E +++
Sbjct: 352 RREQEEERREQQLRREQEEERREQ 375
Score = 40.8 bits (94), Expect = 0.003
Identities = 49/241 (20%), Positives = 102/241 (42%), Gaps = 10/241 (4%)
Query: 167 EEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQESQ----GLL 222
+EEEE + R E E Q + E +R+ E + +E Q L
Sbjct: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL 966
Query: 223 HPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQK-QKQEQVQD 281
+E Q+L E+ ++ E RE+ + EEQ++ + +++ Q+ ++Q + +D
Sbjct: 967 QQKEEQLLGEEPEKRRRQEREKKYREE--EELQQEEEQLLREEREKRRRQEWERQYRKKD 1024
Query: 282 VMLGRQGERMGLTGEPEGLNDGEW---EQEDMERKAQGQGGPEQGEERKRELQVPEENRA 338
+ + + + E L + E E+E+++++ + G E+ R++EL+
Sbjct: 1025 ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEE 1084
Query: 339 DSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKEPESWDGGRLGAVGRARSREE 398
+ Q E+ Q + E+ ++ + +E+ +E E + R + R EE
Sbjct: 1085 ELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEE 1144
Query: 399 E 399
E
Sbjct: 1145 E 1145
Score = 40.4 bits (93), Expect = 0.004
Identities = 56/241 (23%), Positives = 100/241 (41%), Gaps = 37/241 (15%)
Query: 169 EEETSSDNSGQTRYYSPCEEHPAETNQNEGA---ESGTIRQGEELPSEELQESQGLLHPQ 225
EE+ Q R + EE E + E E +++ E ELQE + L
Sbjct: 224 EEKQQQRRERQDRVFQ--EEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL 281
Query: 226 EVQVL----EEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQD 281
E Q L +E+ QQ+ R E LR EE+ EQ +E+ EQ++++EQ
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQ-------EEERREQ-QEERREQQERREQ--- 330
Query: 282 VMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQ 341
Q ER + + +E ER+ Q ++ E R+++L+ +E Q
Sbjct: 331 -----QEER----------REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQ 375
Query: 342 DEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKEPESWDGGRLGAVGRARSREEENE 401
+ + L + +++ ++E +E+ + Q +E + +L + R +EE
Sbjct: 376 QLRREQQLRREQQL--RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEER 433
Query: 402 H 402
H
Sbjct: 434 H 434
Score = 39.3 bits (90), Expect = 0.008
Identities = 61/266 (22%), Positives = 107/266 (40%), Gaps = 46/266 (17%)
Query: 146 EEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIR 205
EEEE E+ T L +EEE+ + + R +E + + E E R
Sbjct: 240 EEEEKEWRKRETVLR------KEEEKLQEEEPQRQR---ELQEEEEQLRKLERQELRRER 290
Query: 206 QGEELPSEELQESQGLLHPQEVQVLEEQGQ--------QEAGFRGEGTLREDVCADGLLG 257
Q EE + L+ Q L QE + E+Q + ++ R E LR +
Sbjct: 291 QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE---QEERR 347
Query: 258 EEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQ 317
E+Q+ + +E+ EQ+ ++EQ ++ E + + + +E R+ Q Q
Sbjct: 348 EQQLRREQEEERREQQLRREQEEE------------RREQQLRREQQLRREQQLRREQ-Q 394
Query: 318 GGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAK 377
EQ R+++L+ ++ R + Q + Q + EE +Q+ +E+ +E +
Sbjct: 395 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHE--QERREQRLKREQE 452
Query: 378 EPESWDGGRLGAVGRARSREEENEHH 403
E W REEE E H
Sbjct: 453 ERRDW-----------LKREEETERH 467
Score = 35.4 bits (80), Expect = 0.12
Identities = 43/177 (24%), Positives = 81/177 (45%), Gaps = 20/177 (11%)
Query: 213 EELQESQGLLHPQEVQVLEEQGQ------QEAGFRGEGTLREDVCADGLLGEEQMIEQVN 266
E+L++ Q LL +E ++ E+ + QE +R E L+++ + LL EE+ +
Sbjct: 897 EQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQE--EEQLLREEREKRRRQ 954
Query: 267 --------DEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQG 318
D+K +QK++Q ++ R+ ER E E L E + ER+ + +
Sbjct: 955 ERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ 1014
Query: 319 GPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQE 375
E+ +K ELQ EE + EK + E +E+ ++++ + G+E
Sbjct: 1015 EWERQYRKKDELQQEEEQLLREEREKRRL----QERERQYREEEELQQEEEQLLGEE 1067
Score = 33.5 bits (75), Expect = 0.44
Identities = 57/235 (24%), Positives = 90/235 (38%), Gaps = 41/235 (17%)
Query: 167 EEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQ-ESQGLLHPQ 225
EEEEE + E+ AE Q + E R +P + Q ES+
Sbjct: 662 EEEEERLEQRLKREHEEERREQELAEEEQEQARE----RIKSRIPKWQWQLESEADARQS 717
Query: 226 EV--QVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVM 283
+V + +++GQ+ + E R E ++ Q + Q+Q++EQ +D
Sbjct: 718 KVYSRPRKQEGQRRRQEQEEKRRRR---------ESELQWQEEERAHRQQQEEEQRRDFT 768
Query: 284 LGRQGE------RMGLTGEPEGLNDGEWEQEDMERKAQGQGG-PEQGE---------ERK 327
Q E R L+ P E + ER+ + Q PE+ E ER+
Sbjct: 769 WQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRERE 828
Query: 328 RELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKEPESW 382
+ELQ EE + E++Q EE G QED + QE + + W
Sbjct: 829 KELQFLEEEEQLQRRERAQQL---QEEEDGLQEDQERRR------SQEQRRDQKW 874
Score = 33.5 bits (75), Expect = 0.44
Identities = 53/248 (21%), Positives = 93/248 (37%), Gaps = 21/248 (8%)
Query: 165 QAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQESQGLLHP 224
Q EE R Y EE E Q E RQ E E +E Q
Sbjct: 1152 QLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRK 1211
Query: 225 QEVQVLEEQGQQEAGFRGEGTLREDVCADGLL----GEEQMIEQVNDEKGEQKQKQEQVQ 280
Q + +++ + + E +E+ D + E + Q+ D + +Q Q+ +Q
Sbjct: 1212 QRYRDEDQRSDLKWQWEPE---KENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQ 1268
Query: 281 DVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADS 340
+LG Q ER W+Q D + Q E+ +E KR + +E +
Sbjct: 1269 H-LLGEQQER------DREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLL 1321
Query: 341 QDEKSQTFLGKSEEVTGKQEDHGIKEK-GVPVSGQE------AKEPESWDGGRLGAVGRA 393
++E+ + + + ++E+ ++E+ P+ QE +E + GR
Sbjct: 1322 REEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQ 1381
Query: 394 RSREEENE 401
R R +E E
Sbjct: 1382 RLRRQERE 1389
Score = 33.5 bits (75), Expect = 0.44
Identities = 65/294 (22%), Positives = 117/294 (39%), Gaps = 59/294 (20%)
Query: 167 EEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQESQGLLHPQE 226
EE + + Q R+ + E EG E RQ + E +E Q +E
Sbjct: 1648 EEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFRE-EEQQLRRQERE 1706
Query: 227 VQVLEEQGQQ-----EAGFRGEGTLREDVCADGLLGEE------------------QMIE 263
+ L+E+ Q E FR E LR++ + L +E Q+
Sbjct: 1707 RKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRR 1766
Query: 264 QVNDEK-GEQKQKQEQVQDVMLG--------RQGERMGLTGEPEGL----NDGE--WEQE 308
Q D K E++Q +++ ++ L R+ E++ E + L DG+ WE+E
Sbjct: 1767 QERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEE 1826
Query: 309 DMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQE-DHGIKEK 367
++ + Q Q +ER R+ + E+ + + + L + EE +QE + ++E+
Sbjct: 1827 QLQLEEQEQ---RLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREE 1883
Query: 368 GVPVSGQEAKEPESWDGGRLGAVGRARSRE--------EENEHHGPSMPALIAP 413
+ ++ KE + R VG +S+E E H S+P +P
Sbjct: 1884 HI---RRQQKEEQ-----RHRQVGEIKSQEGKGHGRLLEPGTHQFASVPVRSSP 1929
Score = 32.7 bits (73), Expect = 0.76
Identities = 42/204 (20%), Positives = 77/204 (37%), Gaps = 19/204 (9%)
Query: 162 GSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPS---EELQES 218
G + +E+EE + ++ H + + + + Q EE + L
Sbjct: 728 GQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSAR 787
Query: 219 QGLLHPQEVQV-LEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQE 277
L +E Q+ EE+ Q+E F E EE+ ++ + +K+ Q
Sbjct: 788 PPLREQRERQLRAEERQQREQRFLPE--------------EEEKEQRRRQRREREKELQF 833
Query: 278 QVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENR 337
++ L R+ L E +GL + + + E++ + + EERKR
Sbjct: 834 LEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKP 893
Query: 338 A-DSQDEKSQTFLGKSEEVTGKQE 360
A Q K Q L + EE ++E
Sbjct: 894 ALQEQLRKEQQLLQEEEEELQREE 917
Score = 32.0 bits (71), Expect = 1.3
Identities = 48/220 (21%), Positives = 83/220 (37%), Gaps = 12/220 (5%)
Query: 146 EEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEE---HPAETNQNEGAESG 202
+E+E +F L GQ + +E + EE H E ++ E
Sbjct: 1591 QEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEP 1650
Query: 203 TIRQGEELPS------EELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLL 256
+R+ E + +E + LL E Q L Q + E LR L
Sbjct: 1651 QLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFL 1710
Query: 257 GEEQMIEQVNDEKG--EQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKA 314
EEQ + + E+ E++Q +++ + L RQ ER E E L EQ+ ++
Sbjct: 1711 QEEQQLRRQELERKFREEEQLRQETEQEQLRRQ-ERYRKILEEEQLRPEREEQQLRRQER 1769
Query: 315 QGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEE 354
+ E+ ++RE Q +D + + + + EE
Sbjct: 1770 DRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREE 1809
Score = 29.6 bits (65), Expect = 6.4
Identities = 47/220 (21%), Positives = 83/220 (37%), Gaps = 39/220 (17%)
Query: 170 EETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQ------------- 216
E+ D + R + + H E Q E E ++ + EE Q
Sbjct: 1273 EQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQ 1332
Query: 217 -------ESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEK 269
E + LL +E Q L Q +++ FR E LR L EEQ + + E+
Sbjct: 1333 ETDRKFREEEQLLQEREEQPLRRQ-ERDRKFREE-ELRHQEQGRKFLEEEQRLRRQERER 1390
Query: 270 GEQKQKQE---QVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEER 326
K++Q+ Q ++ L + +R + E + ER + + +Q +
Sbjct: 1391 KFLKEEQQLRCQEREQQLRQDRDRK--------FREEEQQLSRQERDRKFREEEQQVRRQ 1442
Query: 327 KRELQVPEENRADSQD------EKSQTFLGKSEEVTGKQE 360
+RE + EE + Q+ E+ Q + E+ +QE
Sbjct: 1443 ERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQE 1482
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 51.6 bits (122), Expect = 2e-06
Identities = 63/256 (24%), Positives = 112/256 (43%), Gaps = 61/256 (23%)
Query: 163 SGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQESQGLL 222
S EE +TS+ +T+ +E E + NE A++G + E SE+
Sbjct: 49 SDMMEENIDTSAQAVAETK-----QEAVVEEDYNENAKNGEAKITEAPASEK-------- 95
Query: 223 HPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIE--------------QVNDE 268
E+ ++E+ ++A +G G +E V A+ EE E + DE
Sbjct: 96 ---EIVEVKEENIEDATEKG-GEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDE 151
Query: 269 KGEQ--------KQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQG-- 318
KGE+ +K E ++ G++GE GE +G GE E+E+ +RK G G
Sbjct: 152 KGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGE-DGKEKGEDEKEEEDRKETGDGKE 210
Query: 319 ---GPEQGEERK----------RELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIK 365
G E+G++++ +E + +E+ +++E + EE GK+ED +
Sbjct: 211 NEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKE 270
Query: 366 EKGVPVSGQEAKEPES 381
+ G + +EP+S
Sbjct: 271 DDG------KKEEPQS 280
Score = 44.3 bits (103), Expect = 3e-04
Identities = 35/155 (22%), Positives = 69/155 (44%), Gaps = 2/155 (1%)
Query: 230 LEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGE 289
++ Q A + E + ED + GE ++ E EK + K+E ++D +
Sbjct: 56 IDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEK 115
Query: 290 RMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFL 349
+ + E + + + E E+ + + +G+ G E +E+ E ++N + ++ +
Sbjct: 116 KEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKED 175
Query: 350 GKSEEVTGKQEDHGIKEKGVPVSGQEAKEPESWDG 384
GK E GK KEKG +E ++ E+ DG
Sbjct: 176 GKKGE-DGKGNGEDGKEKGEDEKEEEDRK-ETGDG 208
Score = 31.6 bits (70), Expect = 1.7
Identities = 54/281 (19%), Positives = 106/281 (37%), Gaps = 35/281 (12%)
Query: 25 EAPMRSSQVSALGLEAQEDEDPSYKWREEHRLSATQQSELRDVCDYAIETMPSFPKEGSA 84
E RS+++SA+ + + P K R T+ + + D + + + +E
Sbjct: 15 EPKRRSARLSAMLVPVTPEVKP--KRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVV 72
Query: 85 DVEPNQESLVAEACDTP------EHWEAVPQSLAGRQARTLAPPELWACPIQSEHLDMAP 138
+ + N+ + EA T E E +++ + E A +++E D
Sbjct: 73 EEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKE 132
Query: 139 FSSDLGSEEEEVEFWPGLTSLTLGSGQAEE--EEETSSDNSGQTRYYSPCEEHPAET--- 193
D E+ E G +E EE+ D +G + E+ +
Sbjct: 133 DEEDQNEEKGEA-----------GKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGED 181
Query: 194 ---NQNEGAESGTIRQGEE--------LPSEELQESQGLLHPQEVQVLEEQGQQEAGFRG 242
N +G E G + EE +E+ +E ++V+V E++ ++E G
Sbjct: 182 GKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKED 241
Query: 243 EGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVM 283
EG E+ + +E+ + DE E K+E+ Q ++
Sbjct: 242 EGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQSIV 282
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 51.2 bits (121), Expect = 2e-06
Identities = 54/249 (21%), Positives = 115/249 (46%), Gaps = 17/249 (6%)
Query: 140 SSDLGSEEEEVEFWPGLTSLTLGS--GQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNE 197
S+ +G+ E E PG L L Q E +++ + Q + + ++ P + Q +
Sbjct: 70 SAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQ 129
Query: 198 GAE-----SGTIRQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCA 252
++ ++ E P +L Q L PQ+VQ + QQ+ + + + V
Sbjct: 130 LSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQV-- 187
Query: 253 DGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMER 312
L +EQ+ +QV +++ Q Q+QEQ+Q L +Q E++ + + +Q+ +
Sbjct: 188 --LQQQEQLQQQVQEQQLLQ-QQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLL 244
Query: 313 KAQGQGGPE--QGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVP 370
+ QGQ + Q ++ + + Q+ E+ +A Q Q L + E++ +Q+ ++++
Sbjct: 245 QQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQ---QQLLLQQQEQLQQQQQQQLLQQQQEQ 301
Query: 371 VSGQEAKEP 379
+ Q+ + P
Sbjct: 302 LQQQQLQPP 310
Score = 43.5 bits (101), Expect = 4e-04
Identities = 50/215 (23%), Positives = 90/215 (41%), Gaps = 33/215 (15%)
Query: 154 PGLTSLTLGSGQAE--EEEETSSDNSGQTR--YYSPCEEHPAETNQNEGAESGTIRQGEE 209
PG +L+ GSG +E EEEE NS R +P G ++Q E+
Sbjct: 37 PGPDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQ 96
Query: 210 LPSEELQ-ESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDE 268
P + Q + + L PQ L++Q QQ+ +Q + Q+ E
Sbjct: 97 QPEPQQQPQHEQLQQPQPHLELQQQPQQDG--------------------QQQLSQLQQE 136
Query: 269 KGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKR 328
K + QE ++ L Q +++ +P+ + + + Q+ E+ Q +Q +++
Sbjct: 137 KHQSVHHQELKPELQLMHQQQQL----QPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQE 192
Query: 329 EL--QVPEENRADSQDE--KSQTFLGKSEEVTGKQ 359
+L QV E+ Q E + Q L + E++ +Q
Sbjct: 193 QLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQ 227
Score = 40.0 bits (92), Expect = 0.005
Identities = 51/211 (24%), Positives = 101/211 (47%), Gaps = 22/211 (10%)
Query: 161 LGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQESQG 220
L + QA+E++ Q + E+ + Q + + ++Q E+L ++ Q+ Q
Sbjct: 177 LQTQQAQEQQVLQQQEQLQQQVQ---EQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQE 233
Query: 221 LLHPQE-VQVLEEQGQ--QEAGFRGEGTLREDVCADGLLGEEQMI-----EQVNDEKGEQ 272
L Q+ + +L++QGQ Q+ + + L++ + +Q + EQ+ ++ +Q
Sbjct: 234 QLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQ 293
Query: 273 --KQKQEQVQDVMLG------RQGERMGLTGEPEGL-NDGEWEQEDMERKAQGQGGPEQG 323
+Q+QEQ+Q L + E + L P L ++ E EQ+ E + Q Q Q
Sbjct: 294 LLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQ-QELERQQ 352
Query: 324 EERKRELQVPEE-NRADSQDEKSQTFLGKSE 353
E+R+ +L++ EE + + Q E+ Q L + E
Sbjct: 353 EQRQLQLKLQEELQQLEQQLEQQQQQLEQQE 383
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 50.4 bits (119), Expect = 4e-06
Identities = 47/221 (21%), Positives = 87/221 (39%), Gaps = 15/221 (6%)
Query: 143 LGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESG 202
L E+EE G + +++ EEE + T +P + + +N G +
Sbjct: 687 LAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQED 746
Query: 203 TIRQGE--ELPSEELQES-QGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEE 259
E+P EE + + +G + + +G+ E +G+G ED E
Sbjct: 747 VAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECED---------E 797
Query: 260 QMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGG 319
E D +GE + + M G +GE E + + +++ +E GG
Sbjct: 798 NEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGG 857
Query: 320 PEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQE 360
+ EE + E Q EE + ++E+ + + EE G +E
Sbjct: 858 DSEEEEEEEEEQEEEEEEEEQEEEEEEE---EEEEEKGNEE 895
Score = 43.9 bits (102), Expect = 3e-04
Identities = 51/219 (23%), Positives = 78/219 (35%), Gaps = 17/219 (7%)
Query: 192 ETNQNEGAESGTIRQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVC 251
E + N+GA + + E P EE + V + +G Q+ G+ + E
Sbjct: 693 EESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEAES 752
Query: 252 ADGLLGEEQMI--EQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQED 309
+ GEE E +EK + + E + +GE E EG D E E E
Sbjct: 753 TGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEG 812
Query: 310 MERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGV 369
G+ +GE +EL A DEK G S+ ++E+ +E+
Sbjct: 813 EIHAEDGEMKGNEGETESQELSAENHGEA-KNDEKGVEDGGGSDGGDSEEEEEEEEEQEE 871
Query: 370 PVSGQEAKEPESWDGGRLGAVGRARSREEENEHHGPSMP 408
+E +E E EEE E G P
Sbjct: 872 EEEEEEQEEEE--------------EEEEEEEEKGNEEP 896
Score = 40.4 bits (93), Expect = 0.004
Identities = 58/232 (25%), Positives = 83/232 (35%), Gaps = 33/232 (14%)
Query: 106 AVPQSLAGRQARTLAPPELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQ 165
A PQ+ A + P +L A + AP G ++E PG G
Sbjct: 702 AQPQAKAESKPEEEEPAKLPAVTVTP-----APVPDIKGDQKEN----PG------GQED 746
Query: 166 AEEEEETSS--DNSGQTRYYSPCEEHPAETNQNEG-AESGTIRQGEELPSEELQESQGLL 222
E E T G+T EE Q EG E+ T +GEE E E +G
Sbjct: 747 VAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKG-- 804
Query: 223 HPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDV 282
+ +G+ E E D G GE + E + GE K ++ V+D
Sbjct: 805 --------DNEGEDEGEIHAE-----DGEMKGNEGETESQELSAENHGEAKNDEKGVEDG 851
Query: 283 MLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPE 334
G+ E E + E E+E E + + + E+G E L PE
Sbjct: 852 GGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPE 903
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 47.0 bits (110), Expect = 4e-05
Identities = 47/231 (20%), Positives = 104/231 (45%), Gaps = 18/231 (7%)
Query: 167 EEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSEE--LQESQGLLHP 224
E+EE+ E+ E + + +R+ E + E ++E + ++
Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 607
Query: 225 QEVQVLEE----QGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQ 280
QE ++ E+ Q Q+E + E ++E + + +E+ + + ++ EQ++ EQ +
Sbjct: 608 QEEKMQEQEEKMQEQEEKMWEQEEKMQEQ--EEKMWEQEEKMWEQEEKMWEQQRLPEQKE 665
Query: 281 DVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADS 340
+ + E+M + + + WEQE ME+K Q Q +E+ RE + E
Sbjct: 666 KLW---EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKM 722
Query: 341 QDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAK----EPESWDGGRL 387
++E+ + + +E ++++ ++E+ + QE K E + W+ RL
Sbjct: 723 REEEE---MMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRL 770
Score = 42.0 bits (97), Expect = 0.001
Identities = 56/255 (21%), Positives = 115/255 (45%), Gaps = 25/255 (9%)
Query: 147 EEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQ 206
E+E + W L Q E+E+ D + R + +E E + + Q
Sbjct: 366 EQEEKMWRQEERLWEQEKQMREQEQKMRDQ--EERMWEQ-DERLREKEERMREQEKMWEQ 422
Query: 207 GEELPSEE-LQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQV 265
E++ E+ +QE + QE ++ EE+ +E E +RE+ + + +E+ +++
Sbjct: 423 VEKMREEKKMQEQEKKTRDQEEKMQEEERIRER----EKKMREE--EETMREQEEKMQKQ 476
Query: 266 NDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEE 325
+ EQ++K+ Q Q L Q E++ + + + WEQE+ R + G E+
Sbjct: 477 EENMWEQEEKEWQQQ--RLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW 534
Query: 326 RKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKEPESWD-G 384
R+ +++ +E++ Q+EK + E+ QE+ K+ + +E ++WD
Sbjct: 535 RQEKMR-EQEDQMWEQEEK----MRDQEQKMWDQEERMEKK-------TQEQEKKTWDQE 582
Query: 385 GRLGAVGRARSREEE 399
++ R R RE++
Sbjct: 583 EKMREEERMREREKK 597
Score = 41.6 bits (96), Expect = 0.002
Identities = 55/267 (20%), Positives = 115/267 (43%), Gaps = 41/267 (15%)
Query: 168 EEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEEL-PSEELQESQGLLHPQE 226
EEEET + Q EE+ E + E + Q E+L E++QE + + QE
Sbjct: 461 EEEETMRE---QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE 517
Query: 227 VQVLEEQ---GQQEAGFRGEGTLREDVCADGLLGEEQMI---EQVNDEKGEQKQKQEQVQ 280
++ +++ GQ++ +R E ++ D + +E+ + EQ ++ E+ +K+ Q Q
Sbjct: 518 EKIRDQEEMWGQEKKMWRQEKMREQE---DQMWEQEEKMRDQEQKMWDQEERMEKKTQEQ 574
Query: 281 DVMLGRQGERMG-----------LTGEPEGLNDGE-----------------WEQEDMER 312
+ Q E+M + E E + + E WEQE+ +
Sbjct: 575 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQ 634
Query: 313 KAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVS 372
+ + + ++ + ++E ++ E+ R Q EK E+ ++++ I E+
Sbjct: 635 EQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEK 694
Query: 373 GQEAKEPESWDGGRLGAVGRARSREEE 399
+ +E ++WD ++ R RE++
Sbjct: 695 KTQEQEKKTWDQEKMREEESMREREKK 721
Score = 40.4 bits (93), Expect = 0.004
Identities = 50/217 (23%), Positives = 101/217 (46%), Gaps = 35/217 (16%)
Query: 187 EEHPAETNQNEGAESGTIRQGEELPSEELQESQGLLHPQEVQVLEE----QGQQEAGFRG 242
E+ +Q + E ++R+ E+ +++E + ++ QE ++ E+ Q Q+E +
Sbjct: 698 EQEKKTWDQEKMREEESMREREK----KMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQ 753
Query: 243 EGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLND 302
E + E + + E+Q + + ++ E ++ QEQ + + + E + D
Sbjct: 754 EEKMWEQ---EEKMWEQQRLPEQKEKLWEHEKMQEQEK------------IWEQEEKMRD 798
Query: 303 GEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDH 362
E + E K +GQ +G+E K +E + Q+EK G+ E++ G++E
Sbjct: 799 QEEKMRGQEEKMRGQEEKMRGQEEK---MWGQEEKMWGQEEK---MWGQEEKMWGQEEK- 851
Query: 363 GIKEKGVPVSGQEAKEPESWDGGRLGAVGRARSREEE 399
++EK + GQE K E + R G + R +EE+
Sbjct: 852 -MEEK---MQGQEEKMREQEEKMR-GQEEKMREQEEK 883
Score = 35.8 bits (81), Expect = 0.089
Identities = 51/215 (23%), Positives = 96/215 (44%), Gaps = 22/215 (10%)
Query: 193 TNQNEGAESGTIRQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCA 252
T NE + E+LP E ++S+ L+ +E++ E+ + TL+E++
Sbjct: 217 TITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWR 276
Query: 253 DGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMG-LTGEPEGLNDGEWEQEDME 311
EE++ EQ EK +KQ+++ + RQ ER+ G+ + W QE
Sbjct: 277 Q----EEELREQ---EKKIRKQEEK------MWRQEERLREQEGKMREQEEKMWRQEKRL 323
Query: 312 RKAQGQGGPEQGEERKRELQVPEENRADSQDEK---SQTFLGKSEEVTGKQEDHGIKEKG 368
R+ + + ++ E R+++ +E + Q+EK + + + EE +QE+ + E+
Sbjct: 324 REQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER-LWEQE 382
Query: 369 VPVSGQEAK----EPESWDGGRLGAVGRARSREEE 399
+ QE K E W+ R RE+E
Sbjct: 383 KQMREQEQKMRDQEERMWEQDERLREKEERMREQE 417
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 47.0 bits (110), Expect = 4e-05
Identities = 54/248 (21%), Positives = 112/248 (45%), Gaps = 26/248 (10%)
Query: 147 EEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQ 206
E+E + W + + E+EE + R +E E + + IR+
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQ---DEKIQEQEEEMWRQEEKIRE 399
Query: 207 GEELPSEELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVN 266
EE E++ + + Q+ ++ E Q+E +R E +RE + + +E+ + +V
Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIRE---QEEEMWRQEEKIRE--LEEMMQDQEEKLREVE 454
Query: 267 DEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEER 326
++ E+++K ++ Q+ + RQ E++ + + W QE + ++ + E+ R
Sbjct: 455 EKMQEEEEKMQE-QEEKIQRQEEKI------QEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507
Query: 327 KRELQVPEENRADSQDEKSQTFLGK--SEEVTGKQEDHGIKEKGVPVSGQEAKEPESWDG 384
+ E +E + Q+EK Q K +EV Q++ ++E+ V + QE +E
Sbjct: 508 QEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRL--QELEE------ 559
Query: 385 GRLGAVGR 392
RLG +G+
Sbjct: 560 -RLGKLGQ 566
Score = 33.1 bits (74), Expect = 0.58
Identities = 54/201 (26%), Positives = 86/201 (42%), Gaps = 42/201 (20%)
Query: 205 RQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQ 264
R G+EL S + Q + E+ L Q Q+E +R E ++E EE+M EQ
Sbjct: 266 RLGKELQSVSAK-LQAQVEENELWNLLNQQQEEKMWRQEEKIQEQ--------EEKMCEQ 316
Query: 265 VNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEP-EGLNDGEWEQEDMERKAQGQGGPEQG 323
E K ++ Q+ + RQ E+M E D W QE+ R+
Sbjct: 317 ------ELKIRE---QEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQ--------- 358
Query: 324 EERKRELQVP---EENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKEPE 380
EE+ RE + +E + QDEK Q + EE +QE+ I+E+ +E ++ +
Sbjct: 359 EEKIREQEEKMWRQEEKIREQDEKIQ----EQEEEMWRQEEK-IREQ------EEKRQEK 407
Query: 381 SWDGGRLGAVGRARSREEENE 401
W + + RE+E E
Sbjct: 408 MWRQEKKMREQDEKIREQEEE 428
Score = 30.0 bits (66), Expect = 4.9
Identities = 39/174 (22%), Positives = 72/174 (41%), Gaps = 23/174 (13%)
Query: 147 EEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQ 206
E+E E W Q E+ E Q EE E + + I++
Sbjct: 424 EQEEEMWR----------QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQR 473
Query: 207 GEELPSEELQES--QGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQ 264
EE E+ +++ Q L QE ++ E Q+E +R E + E + + +E+ +++
Sbjct: 474 QEEKIQEQEEKTWRQEKLLKQEEKIWE---QEEKMWRQEEKMWEQ--EEKMQEQEEKMQR 528
Query: 265 VNDEKGEQK------QKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMER 312
++ EQ+ +++ Q Q+V L ER+G G+ L G + +R
Sbjct: 529 QEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQR 582
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 47.0 bits (110), Expect = 4e-05
Identities = 54/248 (21%), Positives = 112/248 (45%), Gaps = 26/248 (10%)
Query: 147 EEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQ 206
E+E + W + + E+EE + R +E E + + IR+
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQ---DEKIQEQEEEMWRQEEKIRE 399
Query: 207 GEELPSEELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVN 266
EE E++ + + Q+ ++ E Q+E +R E +RE + + +E+ + +V
Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIRE---QEEEMWRQEEKIRE--LEEMMQDQEEKLREVE 454
Query: 267 DEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEER 326
++ E+++K ++ Q+ + RQ E++ + + W QE + ++ + E+ R
Sbjct: 455 EKMQEEEEKMQE-QEEKIQRQEEKI------QEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507
Query: 327 KRELQVPEENRADSQDEKSQTFLGK--SEEVTGKQEDHGIKEKGVPVSGQEAKEPESWDG 384
+ E +E + Q+EK Q K +EV Q++ ++E+ V + QE +E
Sbjct: 508 QEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRL--QELEE------ 559
Query: 385 GRLGAVGR 392
RLG +G+
Sbjct: 560 -RLGKLGQ 566
Score = 33.1 bits (74), Expect = 0.58
Identities = 54/201 (26%), Positives = 86/201 (42%), Gaps = 42/201 (20%)
Query: 205 RQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQ 264
R G+EL S + Q + E+ L Q Q+E +R E ++E EE+M EQ
Sbjct: 266 RLGKELQSVSAK-LQAQVEENELWNLLNQQQEEKMWRQEEKIQEQ--------EEKMCEQ 316
Query: 265 VNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEP-EGLNDGEWEQEDMERKAQGQGGPEQG 323
E K ++ Q+ + RQ E+M E D W QE+ R+
Sbjct: 317 ------ELKIRE---QEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQ--------- 358
Query: 324 EERKRELQVP---EENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKEPE 380
EE+ RE + +E + QDEK Q + EE +QE+ I+E+ +E ++ +
Sbjct: 359 EEKIREQEEKMWRQEEKIREQDEKIQ----EQEEEMWRQEEK-IREQ------EEKRQEK 407
Query: 381 SWDGGRLGAVGRARSREEENE 401
W + + RE+E E
Sbjct: 408 MWRQEKKMREQDEKIREQEEE 428
Score = 30.0 bits (66), Expect = 4.9
Identities = 39/174 (22%), Positives = 72/174 (41%), Gaps = 23/174 (13%)
Query: 147 EEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQ 206
E+E E W Q E+ E Q EE E + + I++
Sbjct: 424 EQEEEMWR----------QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQR 473
Query: 207 GEELPSEELQES--QGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQ 264
EE E+ +++ Q L QE ++ E Q+E +R E + E + + +E+ +++
Sbjct: 474 QEEKIQEQEEKTWRQEKLLKQEEKIWE---QEEKMWRQEEKMWEQ--EEKMQEQEEKMQR 528
Query: 265 VNDEKGEQK------QKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMER 312
++ EQ+ +++ Q Q+V L ER+G G+ L G + +R
Sbjct: 529 QEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQR 582
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 46.6 bits (109), Expect = 5e-05
Identities = 78/372 (20%), Positives = 168/372 (45%), Gaps = 57/372 (15%)
Query: 80 KEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQARTLAPPELWACPIQSEHL--DMA 137
KE +A ++ + + +E + + + + + L +A+ L P + +++HL ++
Sbjct: 208 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKL--ERAKLLLPQQ--QLQAEADHLGKELQ 263
Query: 138 PFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNE 197
S+ L ++ EE E W L +EE+ + Q + E+ Q E
Sbjct: 264 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEE 323
Query: 198 --GAESGTIRQGEEL---PSEELQESQGLLHPQE--------------VQVLEEQGQQEA 238
+ +R+ EE+ E+++E + +H QE ++ E++ +QEA
Sbjct: 324 MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 383
Query: 239 G-FRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQK------QEQVQDVMLGRQGERM 291
+R E +RE + + +E+M+++ ++ GEQ++K + Q Q+ + RQ E+
Sbjct: 384 KMWRQEEKIREQ--EEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEK- 440
Query: 292 GLTGEPEGLNDGEW---EQEDMERKAQGQGGPEQGEERKRELQVPE-ENRADSQDEK--- 344
+ + + + + E EQE+M ++ + + G ++G+ ++E ++ E E + Q+EK
Sbjct: 441 -IREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIRE 499
Query: 345 -------SQTFLGKSEEVTGKQE------DHGIKEKGVPVSGQEAKEPESWDGGRLGAVG 391
+ + + EE+ +QE + + E+ + QE K + R V
Sbjct: 500 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEV- 558
Query: 392 RARSREEENEHH 403
R R +EE+ + H
Sbjct: 559 RLRQQEEKMQEH 570
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 45.4 bits (106), Expect = 1e-04
Identities = 49/215 (22%), Positives = 93/215 (43%), Gaps = 33/215 (15%)
Query: 165 QAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQESQGLLHP 224
+ +E+E+ + D + R EE E + E +R+ EE ++QE + +
Sbjct: 541 KTQEQEKKTWDQEEKMRE----EERMREREKKMREEEEMMREQEE----KMQEQEEKMRE 592
Query: 225 QEVQVLEE----QGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQK----- 275
QE ++ E+ Q Q+E + E + E D + +E+M+ + ++ EQ++K
Sbjct: 593 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE 652
Query: 276 ------QEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERK-- 327
+E++++ QG+ + + E + E + + E K +GQ G+E K
Sbjct: 653 EKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMW 712
Query: 328 --------RELQVPEENRADSQDEKSQTFLGKSEE 354
+E +E R Q EK Q L + EE
Sbjct: 713 GQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEE 747
Score = 43.5 bits (101), Expect = 4e-04
Identities = 59/226 (26%), Positives = 102/226 (45%), Gaps = 43/226 (19%)
Query: 187 EEHPAETNQNEGAESGTIRQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTL 246
EE E + + E T Q E++ EE + +E +++ EQ E +
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ---------EEKM 583
Query: 247 REDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGE-- 304
+E EE+M EQ +EK +++++ Q Q+ + Q E+M E + + + E
Sbjct: 584 QEQ--------EEKMREQ--EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEM 633
Query: 305 -WEQEDMERKAQGQGGPE-QGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQE-- 360
WEQE+ K Q Q + EE+ RE +E + Q+EK Q G+ E++ ++E
Sbjct: 634 MWEQEE---KMQEQEEKMWEQEEKMRE----QEEKMREQEEKMQ---GQEEKMREQEEKM 683
Query: 361 ---DHGIKEKGVPVSGQEAK----EPESWDGGRLGAVGRARSREEE 399
+ ++E+ + GQE K E + W G G+ RE+E
Sbjct: 684 QGQEEKMREQEEKMRGQEEKMWGQEEKMW-GQEEKMWGQEEMREKE 728
Score = 41.6 bits (96), Expect = 0.002
Identities = 44/207 (21%), Positives = 92/207 (44%), Gaps = 20/207 (9%)
Query: 168 EEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEEL-PSEELQESQGLLHPQE 226
EEEET + Q EE+ E + E + Q E+L E++QE + + QE
Sbjct: 403 EEEETMRE---QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE 459
Query: 227 VQVLEEQ---GQQEAGFRGEGTLRED----VCADGLLGEEQMIEQVNDEKGEQKQKQEQV 279
++ +++ GQ++ +R E ++ + + +EQ + + EQ ++ +
Sbjct: 460 EKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREK 519
Query: 280 QDVM-----LGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPE 334
++ M + +Q E+M + + W+QE+ R+ + E+ + E+ +
Sbjct: 520 EERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 579
Query: 335 ENRADSQDEKSQTFLGKSEEVTGKQED 361
E + Q+EK + + EE +QE+
Sbjct: 580 EEKMQEQEEK----MREQEEKMWEQEE 602
Score = 37.7 bits (86), Expect = 0.024
Identities = 49/208 (23%), Positives = 95/208 (45%), Gaps = 16/208 (7%)
Query: 167 EEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEEL---PSEELQESQGLLH 223
E+EE+ R EE E + + +R EE E L+E + +
Sbjct: 321 EQEEKMREQEEKMWRQ----EERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 376
Query: 224 PQE-VQVLEEQGQQEAGFRG-EGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQD 281
QE + EE+ Q+E R E +RE+ + + +E+ +++ + EQ++K+ Q Q
Sbjct: 377 EQEKMWEQEEKMQEEERIREREKKMREE--EETMREQEEKMQKQEENMWEQEEKEWQQQ- 433
Query: 282 VMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQ 341
L Q E++ + + + WEQE+ R + G E+ R+ +++ +E++ Q
Sbjct: 434 -RLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR-EQEDQMWEQ 491
Query: 342 DEKSQTFLGK--SEEVTGKQEDHGIKEK 367
+EK + K +E ++D ++EK
Sbjct: 492 EEKMRDQEQKMWDQEERMWEQDERLREK 519
Score = 36.6 bits (83), Expect = 0.052
Identities = 51/210 (24%), Positives = 94/210 (44%), Gaps = 46/210 (21%)
Query: 205 RQGEELPSEE--LQESQGLLHPQEVQVLEEQG----QQEAGFRGEGTLREDVCADGLLGE 258
RQ EEL +E +++ + + QE ++ E++G Q+E R E LRE E
Sbjct: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQ--------E 289
Query: 259 EQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQG 318
+++ EQ EK ++QK+ + Q+ + Q E+M WEQE+ R+
Sbjct: 290 KELREQ---EKELREQKKLREQEEQMQEQEEKM-------------WEQEEKMRE----- 328
Query: 319 GPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKE 378
E+ R+ E +E + Q++K + +E ++D ++EK + QE
Sbjct: 329 -QEEKMWRQEERLWEQEKQMREQEQKM-----RDQEERMWEQDERLREKEERMREQE--- 379
Query: 379 PESWD-GGRLGAVGRARSREEENEHHGPSM 407
+ W+ ++ R R RE++ +M
Sbjct: 380 -KMWEQEEKMQEEERIREREKKMREEEETM 408
Score = 32.7 bits (73), Expect = 0.76
Identities = 28/104 (26%), Positives = 57/104 (54%), Gaps = 12/104 (11%)
Query: 258 EEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQ 317
+E+M Q +E+ +++K+ + Q+ + RQ ER+ E EG EQE+ R+ + +
Sbjct: 233 QEEMWRQ--EEELREQEKKIRKQEEKMWRQEERLR---EQEGKMR---EQEEKMRRQEKR 284
Query: 318 GGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQED 361
++ E R++E ++ E+ + Q+E+ Q + EE +QE+
Sbjct: 285 LREQEKELREQEKELREQKKLREQEEQMQ----EQEEKMWEQEE 324
>gi|221316599 chromogranin B precursor [Homo sapiens]
Length = 677
Score = 45.1 bits (105), Expect = 1e-04
Identities = 60/249 (24%), Positives = 99/249 (39%), Gaps = 57/249 (22%)
Query: 166 AEEEEETSSDNSGQTRYYSPCEEH---PAETNQNEGAESGTIRQGEELPSEELQESQGLL 222
+E E +S +G +P EE P + + + AE G + E E Q L
Sbjct: 93 SEAHESSSRGEAG-----APGEEDIQGPTKADTEKWAEGGGHSR------ERADEPQWSL 141
Query: 223 HPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDV 282
+P + QV EE + + E+ E +E+GE QK E+ +D
Sbjct: 142 YPSDSQVSEEVKTRHS-------------------EKSQREDEEEEEGENYQKGERGED- 181
Query: 283 MLGRQGERMGLTGEPEGLND-GEWEQEDMERKAQGQGGPEQGEERKRELQVP--EENRAD 339
+ E + L + GE + + + Q ++ + E + +
Sbjct: 182 -----------SSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTH 230
Query: 340 SQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKEPESWDGGRLGAVGRARSREEE 399
S+++ SQ +S E TG QE+H + KG P S +E++E E V + R+R
Sbjct: 231 SREKSSQ----ESGEETGSQENHPQESKGQPRSQEESEEGEE---DATSEVDKRRTR--P 281
Query: 400 NEHHGPSMP 408
HHG S P
Sbjct: 282 RHHHGRSRP 290
Score = 40.4 bits (93), Expect = 0.004
Identities = 60/252 (23%), Positives = 93/252 (36%), Gaps = 32/252 (12%)
Query: 167 EEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSEEL---QESQGLLH 223
EEEEE + G+ S E+H E + + A +Q + EEL E+ H
Sbjct: 165 EEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGH 224
Query: 224 PQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVM 283
QE E+ QE+ GE T ++ G+ + Q E+GE+ E D
Sbjct: 225 SQEKTHSREKSSQES---GEETGSQENHPQESKGQPR--SQEESEEGEEDATSE--VDKR 277
Query: 284 LGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDE 343
R G + G E+ +G P +E E V + + +D
Sbjct: 278 RTRPRHHHGRSRPDRSSQGGSLPSEE-------KGHP---QEESEESNVSMASLGEKRDH 327
Query: 344 KSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKEPESWD-----GGRLGAVGRARSREE 398
S + EE ++G + KG P G +A E W+ G R +S E
Sbjct: 328 HSTHYRASEEE-----PEYGEEIKGYP--GVQAPEDLEWERYRGRGSEEYRAPRPQSEES 380
Query: 399 ENEHHGPSMPAL 410
+E + P+L
Sbjct: 381 WDEEDKRNYPSL 392
Score = 30.4 bits (67), Expect = 3.8
Identities = 38/191 (19%), Positives = 72/191 (37%), Gaps = 11/191 (5%)
Query: 146 EEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIR 205
+EE+ +P L + G EE EE G+ R++ P ++ E
Sbjct: 382 DEEDKRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFL 441
Query: 206 QGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQV 265
+E Q + HPQ +E + + EG A G ++ ++
Sbjct: 442 GEGHHRVQENQMDKARRHPQ--GAWKELDRNYLNYGEEG-------APGKWQQQGDLQDT 492
Query: 266 NDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEE 325
+ + E + + +Q + +R+G P + +W+ ER+ +GEE
Sbjct: 493 KENREEARFQDKQYSSHHTAEKRKRLGELFNPY-YDPLQWKSSHFERRDNMNDNFLEGEE 551
Query: 326 RKRELQVPEEN 336
+ EL + E+N
Sbjct: 552 -ENELTLNEKN 561
>gi|119220598 apolipoprotein B48 receptor [Homo sapiens]
Length = 1088
Score = 45.1 bits (105), Expect = 1e-04
Identities = 82/354 (23%), Positives = 132/354 (37%), Gaps = 45/354 (12%)
Query: 96 EACDTPEHWEAVPQSLAGRQARTLAPPELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPG 155
EA TP EA L G +ART++ E E + A + G+ E G
Sbjct: 282 EARTTPGREEA-RAILDGEEARTISGGEEAETASGGEEAETASGGEEAGTASGGEE--AG 338
Query: 156 LTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGE--ELPSE 213
+ S +G A EE + + G + T+ E A+ +RQ E +P E
Sbjct: 339 IASGG-EAGTASGGEEAGTASGGDEAW---------TTSGKEEADLLGVRQTEYGAVPGE 388
Query: 214 ELQESQGLLHPQEVQVLEEQGQQEAGFRGE---------GTLREDVCADG------LLGE 258
L E+ G +V VLEE+G +E GT R + A+ +G
Sbjct: 389 RLLEATG-----KVWVLEEEGDEEREAEVSPFPKQPQVLGTERTEEAAESQTAGREAVGG 443
Query: 259 EQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQG 318
++ E + + ++ E QD+ + RM + E + D + G
Sbjct: 444 QEAGESFEGQVDLRGKEAEMRQDLGIRADRARMEELVQAEEAQEERGSSRDPVAELPSDG 503
Query: 319 GPEQGEERKRELQV-PEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSG---Q 374
E + + + PEE + E +QT G G K +G + G
Sbjct: 504 EAEGTADLEATPEARPEEELTGEESEAAQTSCGLLGVEWGGLTHSVTKGQGPELMGGAQT 563
Query: 375 EAKEPESWDGGR---LGAVGRARSREEENEHHGPSMPALIAPEDSPHCDLFPGA 425
K+PE + G +G + ++ +E + GP + PE S + FPGA
Sbjct: 564 PTKQPEEREAGEVELMGVLALSKEEQERSLEAGPRHAGSVKPEAS---EAFPGA 614
Score = 30.4 bits (67), Expect = 3.8
Identities = 53/239 (22%), Positives = 95/239 (39%), Gaps = 23/239 (9%)
Query: 165 QAEEEEE--TSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSE-ELQESQGL 221
+A+E+ E S N G R P ++ E + ++ G S+ E Q+S
Sbjct: 62 EAQEDLEGLRGSQNEGAGRLRGPGDDRRHEVGSSAVEQTWGWGDGSSHGSQAERQDSGAG 121
Query: 222 LHPQEVQVLEEQGQQEAGFR---GEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQ 278
+ + E EA + G G +D +E ++VN E+ + +QE+
Sbjct: 122 ETAKAARCQEPSAHLEARKKSKAGSGAC-QDRSGQAQERQESHEQEVNREERLRSWEQEE 180
Query: 279 VQDVMLGRQGERMGLTGEPEGLNDGEWEQE-DMERKAQGQGGPEQGEERKRELQVPEENR 337
++ + R+ G G + EW + E KA G G+ R+ E V E +
Sbjct: 181 EEEEVRARE------PGMARGA-ESEWTWHGETEGKAGAVGPKAAGDNREMEQGVREADA 233
Query: 338 ADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKEPESWDGGRLGAVGRARSR 396
++++ ++ GK EEV ++ + + EPE W G +GR +R
Sbjct: 234 GETEEPGAEG-AGKGEEVVVVEK--ACESTRAWGTWGPGAEPEDW-----GILGREEAR 284
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 44.3 bits (103), Expect = 3e-04
Identities = 69/295 (23%), Positives = 103/295 (34%), Gaps = 32/295 (10%)
Query: 129 IQSEHLDMAPFSSDLGSEEEE------VEFW-PGLTSLTLGSGQAEEEEETSSDNSGQTR 181
+ EH P G +EE E W G + G EEEEE + G
Sbjct: 332 VSGEHHHHVPDHRHQGHRDEEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEITVQFGHYV 391
Query: 182 YYSPCEEHPAETN--QNEGAESGTIRQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAG 239
H ++ Q+E +P EE +E L Q + +E G
Sbjct: 392 ASHQPRGHKSDEEDFQDEYKTEVPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETG 451
Query: 240 FRGEGTLRE-DVCADGLLGEEQMIEQVNDEKGEQKQKQE----QVQDVMLGRQGERMGLT 294
G+++E G + D+ E+K+K+E +D QGE+
Sbjct: 452 HGQRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEK---- 507
Query: 295 GEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEE 354
G + G +QED E + +G G EE + E + EE D + + + +G
Sbjct: 508 ----GTHHGSRDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLS 563
Query: 355 VTGKQEDHGIKEKGVPVSGQEAKEPESW----DGGRLGAVGRARSREEENEHHGP 405
+E+ +E G E EP R G A S EE E GP
Sbjct: 564 PDHSEEEEEEEE------GLEEDEPRFTIIPNPLDRREEAGGASSEEESGEDTGP 612
>gi|157266264 pleckstrin homology-like domain, family B, member 3
[Homo sapiens]
Length = 640
Score = 44.3 bits (103), Expect = 3e-04
Identities = 77/273 (28%), Positives = 117/273 (42%), Gaps = 54/273 (19%)
Query: 165 QAEEEE-------ETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIR-QGEELPS---- 212
QAEEEE E+S D T + PA T+ EG R QG++L +
Sbjct: 53 QAEEEEVGEGSSTESSRDAPEATPPIAMAATPPASTSSREGVRGAARRLQGQQLEALTRV 112
Query: 213 -------EELQESQGLLHPQ-EVQVL----EEQGQQEAGFRGEGTLREDVCADGLLGEEQ 260
+ELQ + L + EV+V E G++ A R E LRE L E+Q
Sbjct: 113 ALMEQRVKELQRQRKELRIEMEVEVALLRGELAGERVAARREEEQLRE-------LLEQQ 165
Query: 261 MIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGP 320
++++G Q+++QEQ + L ++ +R+ EGL RKAQGQ
Sbjct: 166 A---ASEQRGRQQREQEQRR---LSQERDRL------EGLRQ-------RLRKAQGQLDS 206
Query: 321 EQGEERKRELQVPEENR--ADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKE 378
+ ++R+R LQ +E R D + + E +QE+ G V + +E
Sbjct: 207 QPEDQRERLLQGVQEMREQLDVAQRAYEDLEFQQLERESRQEEEDRDSPGPQVPDPKVQE 266
Query: 379 PE-SWDGGRLGAV-GRARSREEENEHHGPSMPA 409
+ S R GA+ R R EE+ + G M A
Sbjct: 267 LQASMAQHRRGALQHRIRVLEEQLKSLGEQMAA 299
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 43.9 bits (102), Expect = 3e-04
Identities = 57/271 (21%), Positives = 116/271 (42%), Gaps = 24/271 (8%)
Query: 146 EEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIR 205
+E+E + W + + E+EE + E Q E R
Sbjct: 473 QEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEE-----MWR 527
Query: 206 QGEEL-PSEELQESQGLLHPQEVQVLEEQG----QQEAGFRGEGTLREDVCADGLLGEEQ 260
Q E++ EE+ + +H QE ++ +++ Q+E E +RE + + +E+
Sbjct: 528 QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQ--EEKVWRQEE 585
Query: 261 MIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGP 320
I + ++ EQ++K + Q+ M Q E+MG + E + + E + ++ E K + Q
Sbjct: 586 KIREQEEKIREQEEKIRE-QEEMTQEQEEKMG--EQEEKMCEQEEKMQEQEEKMRRQEEK 642
Query: 321 EQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKEPE 380
+ +E+K Q + + ++ + + + EE +QE+ ++E+ + QE K
Sbjct: 643 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK-MQEQEEKMRRQEEK--- 698
Query: 381 SWDGGRLGAVGRARSREEENEHHGPSMPALI 411
W+ R R +EE+ + H + A I
Sbjct: 699 MWE-----QEVRLRQQEEKMQEHQEHLEAAI 724
Score = 41.6 bits (96), Expect = 0.002
Identities = 73/318 (22%), Positives = 137/318 (43%), Gaps = 56/318 (17%)
Query: 80 KEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQARTLAPPELWACPIQSEHL--DMA 137
KE +A ++ + + +E + + + + + L +A+ L P + +++HL ++
Sbjct: 281 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKL--ERAKLLLPQQ--QLQAEADHLGKELQ 336
Query: 138 PFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNE 197
S+ L ++ EE E W L Q +EE+ + Q EE E +
Sbjct: 337 SVSAKLQAQVEENELWNRLN-------QQQEEKMWRQEEKIQE-----WEEKIQEQEEKI 384
Query: 198 GAESGTIRQGEEL---PSEELQESQGLLHPQEVQVLEEQG----QQEAGFRGEGTLREDV 250
+ IR+ EE E + E + + QE + E++ Q+E + E +RE
Sbjct: 385 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL- 443
Query: 251 CADGLLGEEQMIEQVNDEKGEQKQKQE---------QVQDVMLGRQGERMGLTGEPEGLN 301
EE+M EQ + E+K+++E Q Q+ + RQ E+ + + E +
Sbjct: 444 -------EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK--IREQEEKIR 494
Query: 302 DGE---WEQE----DMERKAQGQGGPEQGEERKRELQVPEENRADSQDEK---SQTFLGK 351
+ E W QE + E+ + + EQ E ++E ++ E+ Q EK + + K
Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRK 554
Query: 352 SEEVTGKQED--HGIKEK 367
EE +QE+ H +EK
Sbjct: 555 QEEKMWRQEEKMHDQEEK 572
Score = 38.9 bits (89), Expect = 0.011
Identities = 48/221 (21%), Positives = 103/221 (46%), Gaps = 22/221 (9%)
Query: 165 QAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPS--EELQESQGLL 222
QAE + S + + EE+ N+ E RQ E++ E++QE + +
Sbjct: 325 QAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI 384
Query: 223 HPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDV 282
QE ++ E Q+E R E + E EE+M Q +E +K+++ + Q+
Sbjct: 385 REQEEKIRE---QEEKMRRQEEMMWEK--------EEKMRRQ--EEMMWEKEEKMRRQEE 431
Query: 283 MLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQV-PEENRADSQ 341
M+ + E+ + E +++ E +E E++ + + EQ + +++E ++ +E + Q
Sbjct: 432 MMWEKEEK--IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 489
Query: 342 DEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKEPESW 382
+EK + + EE +QE+ +++ + + ++ E W
Sbjct: 490 EEK----IREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMW 526
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 43.5 bits (101), Expect = 4e-04
Identities = 82/384 (21%), Positives = 155/384 (40%), Gaps = 64/384 (16%)
Query: 2 EAEEAQRGASPPISAIEEFSIIPEAPMRSSQVSALGLEAQEDEDPSYKWREEHRLSATQQ 61
++++A+ G S + E+ E ++ A G EA+ E+ + + E AT++
Sbjct: 544 KSDQAEEGGSEKEGSSEKEE--GEQEEGETEAEAEGEEAEAKEEKKVEEKSEE--VATKE 599
Query: 62 SELRDVC----DYAIETMPSFPKEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQAR 117
+ D + A +P P E P +S V E +P VP+S + +
Sbjct: 600 ELVADAKVEKPEKAKSPVPKSPVEEKGK-SPVPKSPVEEKGKSP-----VPKSPVEEKGK 653
Query: 118 TLAPP----ELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETS 173
+ P E P+ ++ S S EE + + +G G+ +EEEE
Sbjct: 654 SPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAK-----SKAEVGKGEQKEEEEKE 708
Query: 174 SDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGE------------ELPSEELQESQGL 221
+ + EE P + + + AES + L E +E + L
Sbjct: 709 VKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPL 768
Query: 222 LHPQEVQVLEEQG--QQEAGFRG-EGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQ 278
+E + +G ++E +G +G+ +ED+ +G + ++ +EQ EKG
Sbjct: 769 QQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGS------- 821
Query: 279 VQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRA 338
GR+ E+ +T GL D+ + +GG ++ EE+ + E+ +
Sbjct: 822 ------GREEEKGVVT---NGL--------DLSPADEKKGG-DKSEEKVVVTKTVEKITS 863
Query: 339 DSQDEKSQTFLGKSEEVTGKQEDH 362
+ D ++ ++ KS VT K E+H
Sbjct: 864 EGGDGATK-YITKSVTVTQKVEEH 886
Score = 41.2 bits (95), Expect = 0.002
Identities = 61/315 (19%), Positives = 123/315 (39%), Gaps = 36/315 (11%)
Query: 92 SLVAEACDTPEHWEAVPQSLAGRQARTLAPPELWACPIQSEHLDMAPFSSDLGSEEEEVE 151
S+ E + E E P++ A +P + A ++ E + + G EEEE E
Sbjct: 483 SMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEK---EEEEGQEEEEEE 539
Query: 152 FWPGLTSLTLGSGQAEE---EEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGE 208
+ G +E E+E G+T + EE A+ + +S + E
Sbjct: 540 DEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKE 599
Query: 209 ELPSE-ELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVND 267
EL ++ ++++ + P +EE+G+ + + E G+ + + +
Sbjct: 600 ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVP---KSPVEEK-------GKSPVPKSPVE 649
Query: 268 EKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERK 327
EKG+ + V++ G+ E + E+ + KA+ G ++ EE K
Sbjct: 650 EKGKSPVPKSPVEEK--GKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK 707
Query: 328 RELQVPEENRADSQDEKSQTFLGKSEEVTGKQE-----------------DHGIKEKGVP 370
+ P+E + + ++EK + K + + +E + KE+G P
Sbjct: 708 EVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKP 767
Query: 371 VSGQEAKEPESWDGG 385
+ ++ KE +GG
Sbjct: 768 LQQEKEKEKAGGEGG 782
Score = 37.0 bits (84), Expect = 0.040
Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 6/129 (4%)
Query: 259 EQMIEQ--VNDEKGEQKQKQEQV-QDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQ 315
E++IE+ V DEK E ++ + +++ + + E+ E E + E E+ ++
Sbjct: 454 EEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPV 513
Query: 316 GQGGPEQGEER--KRELQVPEENRADSQDEKS-QTFLGKSEEVTGKQEDHGIKEKGVPVS 372
PE EE K E + EE + + KS Q G SE+ +++ G +E+G +
Sbjct: 514 KATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA 573
Query: 373 GQEAKEPES 381
E +E E+
Sbjct: 574 EAEGEEAEA 582
Score = 34.3 bits (77), Expect = 0.26
Identities = 61/286 (21%), Positives = 113/286 (39%), Gaps = 37/286 (12%)
Query: 122 PELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLT--LGSGQAEEEEETSSDNSGQ 179
P++ A ++ +H + + E+E+ E LT++T L EE++E + + +
Sbjct: 439 PKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEE 498
Query: 180 TRYYSPCEEHPAETNQNEGAESGTIRQGE-ELPSEELQESQGLLHPQEVQVLEEQGQQEA 238
EE A A + +++ E E EE QE + +E + + +E
Sbjct: 499 PEAE---EEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEE----EEEDEGAKSDQAEEG 551
Query: 239 GFRGEGTLRE----------DVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQG 288
G EG+ + + A+G E + ++V ++ E K+E V D + +
Sbjct: 552 GSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE 611
Query: 289 -----------ERMGLTGEPEGLNDGEWEQEDMERKAQGQGG---PEQGEERKRELQV-- 332
E G + P+ + + + + + +G P+ E K + V
Sbjct: 612 KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSK 671
Query: 333 -PEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAK 377
P E +A S KS KS+ GK E +EK V + +E K
Sbjct: 672 SPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEK 717
Score = 31.2 bits (69), Expect = 2.2
Identities = 20/81 (24%), Positives = 35/81 (43%)
Query: 321 EQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKEPE 380
E EE++ E + EE A + T EE K+E+ G +E+ G ++ + E
Sbjct: 490 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE 549
Query: 381 SWDGGRLGAVGRARSREEENE 401
+ G+ + +EE E
Sbjct: 550 EGGSEKEGSSEKEEGEQEEGE 570
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 43.5 bits (101), Expect = 4e-04
Identities = 82/384 (21%), Positives = 155/384 (40%), Gaps = 64/384 (16%)
Query: 2 EAEEAQRGASPPISAIEEFSIIPEAPMRSSQVSALGLEAQEDEDPSYKWREEHRLSATQQ 61
++++A+ G S + E+ E ++ A G EA+ E+ + + E AT++
Sbjct: 168 KSDQAEEGGSEKEGSSEKEE--GEQEEGETEAEAEGEEAEAKEEKKVEEKSEE--VATKE 223
Query: 62 SELRDVC----DYAIETMPSFPKEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQAR 117
+ D + A +P P E P +S V E +P VP+S + +
Sbjct: 224 ELVADAKVEKPEKAKSPVPKSPVEEKGK-SPVPKSPVEEKGKSP-----VPKSPVEEKGK 277
Query: 118 TLAPP----ELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETS 173
+ P E P+ ++ S S EE + + +G G+ +EEEE
Sbjct: 278 SPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAK-----SKAEVGKGEQKEEEEKE 332
Query: 174 SDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGE------------ELPSEELQESQGL 221
+ + EE P + + + AES + L E +E + L
Sbjct: 333 VKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPL 392
Query: 222 LHPQEVQVLEEQG--QQEAGFRG-EGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQ 278
+E + +G ++E +G +G+ +ED+ +G + ++ +EQ EKG
Sbjct: 393 QQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGS------- 445
Query: 279 VQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRA 338
GR+ E+ +T GL D+ + +GG ++ EE+ + E+ +
Sbjct: 446 ------GREEEKGVVT---NGL--------DLSPADEKKGG-DKSEEKVVVTKTVEKITS 487
Query: 339 DSQDEKSQTFLGKSEEVTGKQEDH 362
+ D ++ ++ KS VT K E+H
Sbjct: 488 EGGDGATK-YITKSVTVTQKVEEH 510
Score = 41.2 bits (95), Expect = 0.002
Identities = 61/315 (19%), Positives = 123/315 (39%), Gaps = 36/315 (11%)
Query: 92 SLVAEACDTPEHWEAVPQSLAGRQARTLAPPELWACPIQSEHLDMAPFSSDLGSEEEEVE 151
S+ E + E E P++ A +P + A ++ E + + G EEEE E
Sbjct: 107 SMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEK---EEEEGQEEEEEE 163
Query: 152 FWPGLTSLTLGSGQAEE---EEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGE 208
+ G +E E+E G+T + EE A+ + +S + E
Sbjct: 164 DEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKE 223
Query: 209 ELPSE-ELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVND 267
EL ++ ++++ + P +EE+G+ + + E G+ + + +
Sbjct: 224 ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVP---KSPVEEK-------GKSPVPKSPVE 273
Query: 268 EKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERK 327
EKG+ + V++ G+ E + E+ + KA+ G ++ EE K
Sbjct: 274 EKGKSPVPKSPVEEK--GKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK 331
Query: 328 RELQVPEENRADSQDEKSQTFLGKSEEVTGKQE-----------------DHGIKEKGVP 370
+ P+E + + ++EK + K + + +E + KE+G P
Sbjct: 332 EVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKP 391
Query: 371 VSGQEAKEPESWDGG 385
+ ++ KE +GG
Sbjct: 392 LQQEKEKEKAGGEGG 406
Score = 37.0 bits (84), Expect = 0.040
Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 6/129 (4%)
Query: 259 EQMIEQ--VNDEKGEQKQKQEQV-QDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQ 315
E++IE+ V DEK E ++ + +++ + + E+ E E + E E+ ++
Sbjct: 78 EEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPV 137
Query: 316 GQGGPEQGEER--KRELQVPEENRADSQDEKS-QTFLGKSEEVTGKQEDHGIKEKGVPVS 372
PE EE K E + EE + + KS Q G SE+ +++ G +E+G +
Sbjct: 138 KATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA 197
Query: 373 GQEAKEPES 381
E +E E+
Sbjct: 198 EAEGEEAEA 206
Score = 34.3 bits (77), Expect = 0.26
Identities = 61/286 (21%), Positives = 113/286 (39%), Gaps = 37/286 (12%)
Query: 122 PELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLT--LGSGQAEEEEETSSDNSGQ 179
P++ A ++ +H + + E+E+ E LT++T L EE++E + + +
Sbjct: 63 PKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEE 122
Query: 180 TRYYSPCEEHPAETNQNEGAESGTIRQGE-ELPSEELQESQGLLHPQEVQVLEEQGQQEA 238
EE A A + +++ E E EE QE + +E + + +E
Sbjct: 123 PEAE---EEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEE----EEEDEGAKSDQAEEG 175
Query: 239 GFRGEGTLRE----------DVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQG 288
G EG+ + + A+G E + ++V ++ E K+E V D + +
Sbjct: 176 GSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE 235
Query: 289 -----------ERMGLTGEPEGLNDGEWEQEDMERKAQGQGG---PEQGEERKRELQV-- 332
E G + P+ + + + + + +G P+ E K + V
Sbjct: 236 KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSK 295
Query: 333 -PEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAK 377
P E +A S KS KS+ GK E +EK V + +E K
Sbjct: 296 SPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEK 341
Score = 31.2 bits (69), Expect = 2.2
Identities = 20/81 (24%), Positives = 35/81 (43%)
Query: 321 EQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKEPE 380
E EE++ E + EE A + T EE K+E+ G +E+ G ++ + E
Sbjct: 114 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE 173
Query: 381 SWDGGRLGAVGRARSREEENE 401
+ G+ + +EE E
Sbjct: 174 EGGSEKEGSSEKEEGEQEEGE 194
>gi|224458301 family with sequence similarity 186, member A [Homo
sapiens]
Length = 2351
Score = 43.1 bits (100), Expect = 6e-04
Identities = 30/120 (25%), Positives = 60/120 (50%), Gaps = 13/120 (10%)
Query: 257 GEEQMI-----EQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDME 311
G+EQM +Q+ E+ K+ E++ + ++ G+ E + +W++E+M
Sbjct: 830 GQEQMSGMSLKQQLLGERNLLKEHYEKISENWEEKKAWLQMKEGKQEQQSQKQWQEEEMW 889
Query: 312 RKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGI---KEKG 368
++ Q Q P+Q E+ +++ Q R ++E ++ L + EE T K + G+ KE G
Sbjct: 890 KEEQKQATPKQAEQEEKQKQ-----RGQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENG 944
>gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo
sapiens]
Length = 1101
Score = 42.7 bits (99), Expect = 7e-04
Identities = 74/302 (24%), Positives = 116/302 (38%), Gaps = 48/302 (15%)
Query: 123 ELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSD-----NS 177
EL Q E + P DL +E + P SL + E EEE +
Sbjct: 555 ELLGVGPQVEEFSVEPPLDDLSLDEAQFVLAPSCCSLDSAGPRPEVEEENGEEVFLSAYD 614
Query: 178 GQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQESQGLLHPQEVQVLEEQGQQE 237
+ P + EG +G RQ EE Q + E Q E
Sbjct: 615 DLSPLLGPKPPIWKGSGSLEGEAAGCGRQALGQGGEE----------QACWEVGEDKQAE 664
Query: 238 AGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEP 297
G G +RE+ A+G + + ++++GE QE + G + E T
Sbjct: 665 PG--GRLDIREE--AEGSPETKVEAGKASEDRGEAGGSQETKVRLREGSREE----TEAK 716
Query: 298 EGLNDGEWEQEDMERKA-QGQGGPEQGEERKRELQVPE-ENRADSQDEKSQTF-LGKSE- 353
E + G+ + + ME K + GG E +E+++E++ E E R ++Q E + G E
Sbjct: 717 EEKSKGQKKADSMEAKGVEEPGGDEYTDEKEKEIEREEDEQREEAQVEAGRDLEQGAQED 776
Query: 354 -------EVTGKQ--------EDHGIKEKGVPVS------GQEAKEPESWDGGRLGAVGR 392
EV KQ ED G +EKG + G++++ PE+ G G V +
Sbjct: 777 QVAEEKWEVVQKQEAEGVREDEDKGQREKGYHEARKDQGDGEDSRSPEAATEGGAGEVSK 836
Query: 393 AR 394
R
Sbjct: 837 ER 838
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 42.4 bits (98), Expect = 0.001
Identities = 62/239 (25%), Positives = 97/239 (40%), Gaps = 24/239 (10%)
Query: 139 FSSDLGSEEEEVEFWPGLTSL--------TLGSGQAEEEEETSSDNSGQTRYYSP--CEE 188
FSS + E E F + SL +L S + EE EE + R EE
Sbjct: 2213 FSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEE 2272
Query: 189 HPAETNQNEGAESGTIRQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLRE 248
E Q E E ++ +E EE+QE + + +E + EE+ + + E E
Sbjct: 2273 EEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEE----E 2328
Query: 249 DVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEG----LNDGE 304
+ C+ L EE E+ +K +Q + QEQ + + GR+ L G P G + G
Sbjct: 2329 ESCS---LEEEVDREKEILKKEKQFKLQEQRRKSLRGRERVLSILRGVPHGKGRAIRLGV 2385
Query: 305 WEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLG---KSEEVTGKQE 360
+ + + E+ E Q+ E++ + E + FLG K EV GK E
Sbjct: 2386 LKSPLKKLMSTALEMKEKTPVPVPEKQISWEDKKATVVEIPRKFLGTMDKEREVMGKYE 2444
Score = 38.9 bits (89), Expect = 0.011
Identities = 40/170 (23%), Positives = 81/170 (47%), Gaps = 18/170 (10%)
Query: 185 PCEEHPAETNQNEGAESGTIRQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGFRGEG 244
P E+ ++ ++ E E + L E QES +E + EE+ ++E E
Sbjct: 2209 PKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEE 2268
Query: 245 TLREDVCADGLLGEEQMIEQVNDEKGEQK--QKQEQVQD-VMLGRQGERMGLTGEPEGLN 301
E+ GEE+ +E+ +EK ++K +K+E+VQ+ + + E + E E L+
Sbjct: 2269 RKEEEE------GEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLS 2322
Query: 302 DGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGK 351
D E E+E E+ +R++E+ + +E + Q+++ ++ G+
Sbjct: 2323 DEEEEEESCSL--------EEEVDREKEI-LKKEKQFKLQEQRRKSLRGR 2363
Score = 35.4 bits (80), Expect = 0.12
Identities = 31/128 (24%), Positives = 63/128 (49%), Gaps = 16/128 (12%)
Query: 258 EEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQ 317
+E+ QV++ + E+ +E + +L ++ L+ E E + E E+E+ E +
Sbjct: 2210 KEKFSSQVDEVESEEHFSEEM--ESLLDELEKQESLSSEEEEEREEEEEREEEEVR---- 2263
Query: 318 GGPEQGEERKRE-------LQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVP 370
E+ EERK E ++ EE + + EK + + + EEV ++E+ +E+
Sbjct: 2264 ---EEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETES 2320
Query: 371 VSGQEAKE 378
+S +E +E
Sbjct: 2321 LSDEEEEE 2328
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 42.0 bits (97), Expect = 0.001
Identities = 73/333 (21%), Positives = 142/333 (42%), Gaps = 55/333 (16%)
Query: 80 KEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQARTLAPPELWACPIQSEHL--DMA 137
KE +A ++ + + +E + + + + + L +A+ L P + +++HL ++
Sbjct: 220 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKL--ERAKLLLPQQ--QLQAEADHLGKELQ 275
Query: 138 PFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNE 197
S+ L ++ EE E W L +EE+ + Q + EE E +
Sbjct: 276 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ-----EEKIREQEEKI 330
Query: 198 GAESGTIRQGEEL----------PSEELQESQGLLHPQEVQVLEEQG----QQEAGFRGE 243
+ +R+ EE+ E + E + + QE + E++ Q+E + E
Sbjct: 331 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 390
Query: 244 GTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQE---------QVQDVMLGRQGERMGLT 294
+RE EE+M EQ + E+K+++E Q Q+ + RQ E+ +
Sbjct: 391 EKIREL--------EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK--IR 440
Query: 295 GEPEGLNDGE---WEQE----DMERKAQGQGGPEQGEERKRELQVPEENRADSQDEK--- 344
+ E + + E W QE + E+ + + EQ E ++E ++ E+ Q EK
Sbjct: 441 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHE 500
Query: 345 SQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAK 377
+ + K EE +QE+ I+E+ + QE K
Sbjct: 501 QEEKIRKQEEKVWRQEEK-IREQEEKIREQEEK 532
Score = 40.0 bits (92), Expect = 0.005
Identities = 49/198 (24%), Positives = 97/198 (48%), Gaps = 31/198 (15%)
Query: 213 EELQESQGLLHPQEVQVLEE----QGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDE 268
E+++E + + QE ++ E+ Q Q+E ++ E +RE + + +E+ I + +E
Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ--EEKIQEQEEKIRE-QEE 633
Query: 269 KGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGE---WEQEDMERKAQGQGGPEQGEE 325
K ++++ Q Q+ +G Q E+M + E + + E W QE+ R+ + + + EE
Sbjct: 634 KIREQEEMTQEQEEKMGEQEEKM--CEQEEKMQEQEETMWRQEEKIREQEKK--IREQEE 689
Query: 326 RKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKEPESWDGG 385
+ RE +E Q+EK + + EE +QE+ ++E+ + QE K W+
Sbjct: 690 KIRE----QEEMMQEQEEK----MWEQEEKMCEQEEK-MQEQEEKMRRQEEK---MWE-- 735
Query: 386 RLGAVGRARSREEENEHH 403
R R +EE+ + H
Sbjct: 736 ---QEVRLRQQEEKMQEH 750
Score = 35.4 bits (80), Expect = 0.12
Identities = 50/226 (22%), Positives = 98/226 (43%), Gaps = 32/226 (14%)
Query: 165 QAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAESGTIRQGEELPSEELQESQGLLHP 224
+ E+ +E + Q EE E + + I + E++ EE ++ Q +
Sbjct: 421 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 480
Query: 225 QEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVML 284
QE ++ E QE +R + + E EE++ +Q +EK +++++ + Q+ +
Sbjct: 481 QEEKIHE----QEEIWRQKEKMHEQ--------EEKIRKQ--EEKVWRQEEKIREQEEKI 526
Query: 285 GRQGERMGLTGEPEGLNDGEWEQEDM----------ERKAQGQGGPEQGEERKRELQVP- 333
Q E+M E + W +E+ E++ + + + EE+ RE +
Sbjct: 527 REQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKV 586
Query: 334 --EENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAK 377
+E + Q+EK Q + EE KQE+ I+E+ + QE K
Sbjct: 587 WRQEEKIREQEEKRQ----EQEEKMWKQEEK-IREQEEKIQEQEEK 627
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 42.0 bits (97), Expect = 0.001
Identities = 73/317 (23%), Positives = 137/317 (43%), Gaps = 55/317 (17%)
Query: 80 KEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQARTLAPPELWACPIQSEHL--DMA 137
KE +A ++ + + +E + + + + + L +A+ L P + +++HL ++
Sbjct: 220 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKL--ERAKLLLPQQ--QLQAEADHLGKELQ 275
Query: 138 PFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNE 197
S+ L ++ EE E W L Q +EE+ + Q EE E +
Sbjct: 276 SVSAKLQAQVEENELWNRLN-------QQQEEKMWRQEEKIQE-----WEEKIQEQEEKI 323
Query: 198 GAESGTIRQGEEL---PSEELQESQGLLHPQEVQVLEEQGQ----QEAGFRGEGTLREDV 250
+ IR+ EE E + E + + QE + E++ + +E + E +RE
Sbjct: 324 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIREL- 382
Query: 251 CADGLLGEEQMIEQVNDEKGEQKQKQE---------QVQDVMLGRQGERMGLTGEPEGLN 301
EE+M EQ + E+K+++E Q Q+ + RQ E+ + + E +
Sbjct: 383 -------EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK--IREQEEKIR 433
Query: 302 DGE---WEQE----DMERKAQGQGGPEQGEERKRELQVPEENRADSQDEK--SQTFLGKS 352
+ E W QE + E+ + + EQ E ++E ++ E+ Q EK Q + K
Sbjct: 434 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
Query: 353 EEVTGKQED--HGIKEK 367
EE +QE+ H +EK
Sbjct: 494 EEKVWRQEEKMHDQEEK 510
Score = 42.0 bits (97), Expect = 0.001
Identities = 63/275 (22%), Positives = 115/275 (41%), Gaps = 27/275 (9%)
Query: 146 EEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNE-GAESGTI 204
+E+E + W + + E+E+ + E Q E + I
Sbjct: 412 QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 471
Query: 205 RQGEEL-PSEELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIE 263
R+ EE+ +E Q + QE +V Q+E E +RE + + +E+ I
Sbjct: 472 REQEEIWRQKEKMHEQEKIRKQEEKVWR---QEEKMHDQEEKIREQ--EEKMWRQEEKIR 526
Query: 264 QVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQG 323
+ ++ EQ++K + Q+ M+ Q E+M GE E + EQE M R+ + E+
Sbjct: 527 EQEEKIREQEEKIRE-QEEMMQEQEEKM---GEQE---EKMQEQEKMRRQEEKIREQEEK 579
Query: 324 EERKRELQVPEENRADSQDEK---SQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAK--- 377
++E +E + Q+EK + + + EE +QE+ + E+ + QE K
Sbjct: 580 IREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEK-MCEQEEKMQEQEEKMRR 638
Query: 378 -EPESWDGGRLGAVGRARSREEENEHHGPSMPALI 411
E + W+ R R +EE+ + H + A I
Sbjct: 639 QEEKMWE-----QEVRLRQQEEKMQEHQEHLEAAI 668
>gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapiens]
Length = 1790
Score = 42.0 bits (97), Expect = 0.001
Identities = 58/259 (22%), Positives = 103/259 (39%), Gaps = 67/259 (25%)
Query: 146 EEEEVEFWPGLTSLTLGSGQA-----EEEEETSSDNSGQTRYYSPCEEHPAETNQNEGAE 200
EEE+ ++ LTL +A E EEE+SSD Y+ E +E +++E E
Sbjct: 1580 EEEDKDY----LKLTLDQEEATESTVESEEESSSD-------YTEYSEEESEFSESETTE 1628
Query: 201 SGTIRQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQ 260
E PSEE E +E + E +G++ R+++ L
Sbjct: 1629 E---ESESETPSEE--EESSTPESEESESTESEGEK---------ARKNIV---LARRRP 1671
Query: 261 MIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGP 320
M+E+V + KG +++ QE+ ++ + E+E E + G
Sbjct: 1672 MVEEVKEVKGRKEEPQEEQKEPKME--------------------EEEHSEEEESGPAPV 1711
Query: 321 EQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKEPE 380
E+ + + + +PEE A+ S V G E E G S E++
Sbjct: 1712 EESTDPEAQ-DIPEEGSAE------------SASVEGGVESEEESESGSSSSSSESQSGG 1758
Query: 381 SWDGGRLGAVGRARSREEE 399
W G ++ A R+++ ++
Sbjct: 1759 PW-GYQVPAYDRSKNANQK 1776
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 42.0 bits (97), Expect = 0.001
Identities = 48/242 (19%), Positives = 102/242 (42%), Gaps = 31/242 (12%)
Query: 116 ARTLAPPELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSD 175
A T+ PP + P QS H P D P SG ++ T
Sbjct: 1960 AGTMVPPSYSSQPYQSTHPSTNPTLVD-----------PTRHLQQRPSGYVHQQAPTYGH 2008
Query: 176 NSGQTRYYS--PCEEHPAETNQN----EGAESGTIRQGEELPSEELQESQGLLHPQEVQV 229
T+ +S ++ P + +G ++G +R LP ++ Q+ Q Q+ Q
Sbjct: 2009 GLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAG-VRSTAILPEQQQQQQQQQQQQQQQQQ 2067
Query: 230 LEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGE 289
++Q QQ+ + ++ +L ++Q +Q ++ +Q+Q+Q+Q Q +Q +
Sbjct: 2068 QQQQQQQQQYHIRQQQQQQ------ILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQ 2121
Query: 290 RMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFL 349
+ +P+ + +++++ +++ Q Q Q R+LQ + +++Q + S
Sbjct: 2122 QQAAPPQPQPQSQPQFQRQGLQQTQQQQ----QTAALVRQLQ---QQLSNTQPQPSTNIF 2174
Query: 350 GK 351
G+
Sbjct: 2175 GR 2176
Score = 32.7 bits (73), Expect = 0.76
Identities = 25/125 (20%), Positives = 61/125 (48%), Gaps = 10/125 (8%)
Query: 230 LEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGE 289
+ QG Q AG R L E ++Q +Q ++ +Q+Q+Q+Q Q RQ +
Sbjct: 2033 MSAQGVQ-AGVRSTAILPEQ--------QQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQ 2083
Query: 290 RMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFL 349
+ + + + + +Q+ +++ Q Q +Q ++++++ P + + SQ + + L
Sbjct: 2084 QQQILRQQQ-QQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGL 2142
Query: 350 GKSEE 354
++++
Sbjct: 2143 QQTQQ 2147
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 42.0 bits (97), Expect = 0.001
Identities = 87/403 (21%), Positives = 146/403 (36%), Gaps = 74/403 (18%)
Query: 41 QEDEDPSYKWREEHRLSATQQSELRDVCDYAIETMPSFP---KEGSADV-EPNQESLVAE 96
++ ED K +E+ + +S+++ D AIE F +G + E + E +E
Sbjct: 4697 EQVEDTFQKGQEKDKEDPDSKSDIKGE-DNAIEMSEDFDGKMHDGELEEQEEDDEKSDSE 4755
Query: 97 ACDTPEHWEAVPQSLAGRQARTLAPPELWACPIQSE---HLDMAPFSSDLGSEEEEVEFW 153
D +H L G +A L LW + E D + G +EE+ E
Sbjct: 4756 GGDLDKHMG----DLNGEEADKL-DERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELV 4810
Query: 154 PGLTSLTLGSG--------QAEEEEETSSDNSGQ----------TRYYSPCEEHPAETNQ 195
+L G+ + EE+EE +D+ GQ R Y E P NQ
Sbjct: 4811 AKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQ 4870
Query: 196 NEGAESGTI-------------RQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGFRG 242
+ E + GE+ +EE +E +P E++ E+ EA RG
Sbjct: 4871 EKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEE----NPLEIKEKPEEAGHEAEERG 4926
Query: 243 EGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLND 302
E ++ E Q +E + K E +++ G + PE ++
Sbjct: 4927 ETETDQN---------ESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSE 4977
Query: 303 GEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDH 362
+ + + + K + G E G + EE R DS E+ + E ++E
Sbjct: 4978 EQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEE------QVPEALERKEHA 5031
Query: 363 GIKEKGVP-VSGQEAKEPESWDGGRLGAVGRARSREEENEHHG 404
+ GV + +A E G A +E+ E HG
Sbjct: 5032 SCGQTGVENMQNTQAME----------LAGAAPEKEQGKEEHG 5064
Score = 35.0 bits (79), Expect = 0.15
Identities = 51/223 (22%), Positives = 96/223 (43%), Gaps = 53/223 (23%)
Query: 242 GEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQ----------DVMLGRQGE-- 289
GEG G +GE + ++ V+D+ G ++Q ++ Q D +GE
Sbjct: 4666 GEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDN 4725
Query: 290 RMGLTGEPEG-LNDGEW-EQEDMERKAQGQGGP----------EQGEERKRELQVPEENR 337
+ ++ + +G ++DGE EQE+ + K+ +GG E+ ++ L ++
Sbjct: 4726 AIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEE 4785
Query: 338 ADSQDEKSQT------FLGKSEEVTGKQED----HGIKEKGVPVSGQEAKEPESWDGGRL 387
D ++E ++T + E+ K ++ + K+K +E +E E+ DGG+
Sbjct: 4786 EDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQ- 4844
Query: 388 GAVGRARSRE-------EENE---HHG-----PSMPALIAPED 415
G + E +ENE +HG P AL P+D
Sbjct: 4845 ---GEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDD 4884
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.127 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,860,705
Number of Sequences: 37866
Number of extensions: 1197828
Number of successful extensions: 5358
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 77
Number of HSP's successfully gapped in prelim test: 423
Number of HSP's that attempted gapping in prelim test: 3865
Number of HSP's gapped (non-prelim): 1212
length of query: 484
length of database: 18,247,518
effective HSP length: 106
effective length of query: 378
effective length of database: 14,233,722
effective search space: 5380346916
effective search space used: 5380346916
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.