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Search of human proteins with 50962882
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50962882 G patch domain containing 8 [Homo sapiens]
(1502 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50962882 G patch domain containing 8 [Homo sapiens] 3042 0.0
gi|34740327 zinc finger protein 804A [Homo sapiens] 266 1e-70
gi|31791053 zinc finger protein 804B [Homo sapiens] 251 5e-66
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 133 1e-30
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 114 5e-25
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 109 2e-23
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 107 9e-23
gi|50083281 KIAA1853 protein [Homo sapiens] 103 1e-21
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 100 1e-20
gi|60097902 filaggrin [Homo sapiens] 99 2e-20
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 96 3e-19
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 95 6e-19
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 95 6e-19
gi|57864582 hornerin [Homo sapiens] 92 5e-18
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 91 1e-17
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 90 1e-17
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 90 1e-17
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 88 5e-17
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 88 5e-17
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 88 7e-17
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 87 1e-16
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 87 1e-16
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 83 2e-15
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 82 3e-15
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 82 4e-15
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 82 4e-15
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 81 7e-15
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 80 1e-14
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 80 2e-14
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 79 3e-14
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 3042 bits (7886), Expect = 0.0
Identities = 1502/1502 (100%), Positives = 1502/1502 (100%)
Query: 1 MADRFSRFNEDRDFQGNHFDQYEEGHLEIEQASLDKPIESDNIGHRLLQKHGWKLGQGLG 60
MADRFSRFNEDRDFQGNHFDQYEEGHLEIEQASLDKPIESDNIGHRLLQKHGWKLGQGLG
Sbjct: 1 MADRFSRFNEDRDFQGNHFDQYEEGHLEIEQASLDKPIESDNIGHRLLQKHGWKLGQGLG 60
Query: 61 KSLQGRTDPIPIVVKYDVMGMGRMEMELDYAEDATERRRVLEVEKEDTEELRQKYKDYVD 120
KSLQGRTDPIPIVVKYDVMGMGRMEMELDYAEDATERRRVLEVEKEDTEELRQKYKDYVD
Sbjct: 61 KSLQGRTDPIPIVVKYDVMGMGRMEMELDYAEDATERRRVLEVEKEDTEELRQKYKDYVD 120
Query: 121 KEKAIAKALEDLRANFYCELCDKQYQKHQEFDNHINSYDHAHKQRLKDLKQREFARNVSS 180
KEKAIAKALEDLRANFYCELCDKQYQKHQEFDNHINSYDHAHKQRLKDLKQREFARNVSS
Sbjct: 121 KEKAIAKALEDLRANFYCELCDKQYQKHQEFDNHINSYDHAHKQRLKDLKQREFARNVSS 180
Query: 181 RSRKDEKKQEKALRRLHELAEQRKQAECAPGSGPMFKPTTVAVDEEGGEDDKDESATNSG 240
RSRKDEKKQEKALRRLHELAEQRKQAECAPGSGPMFKPTTVAVDEEGGEDDKDESATNSG
Sbjct: 181 RSRKDEKKQEKALRRLHELAEQRKQAECAPGSGPMFKPTTVAVDEEGGEDDKDESATNSG 240
Query: 241 TGATASCGLGSEFSTDKGGPFTAVQITNTTGLAQAPGLASQGISFGIKNNLGTPLQKLGV 300
TGATASCGLGSEFSTDKGGPFTAVQITNTTGLAQAPGLASQGISFGIKNNLGTPLQKLGV
Sbjct: 241 TGATASCGLGSEFSTDKGGPFTAVQITNTTGLAQAPGLASQGISFGIKNNLGTPLQKLGV 300
Query: 301 SFSFAKKAPVKLESIASVFKDHAEEGTSEDGTKPDEKSSDQGLQKVGDSDGSSNLDGKKE 360
SFSFAKKAPVKLESIASVFKDHAEEGTSEDGTKPDEKSSDQGLQKVGDSDGSSNLDGKKE
Sbjct: 301 SFSFAKKAPVKLESIASVFKDHAEEGTSEDGTKPDEKSSDQGLQKVGDSDGSSNLDGKKE 360
Query: 361 DEDPQDGGSLASTLSKLKRMKREEGAGATEPEYYHYIPPAHCKVKPNFPFLLFMRASEQM 420
DEDPQDGGSLASTLSKLKRMKREEGAGATEPEYYHYIPPAHCKVKPNFPFLLFMRASEQM
Sbjct: 361 DEDPQDGGSLASTLSKLKRMKREEGAGATEPEYYHYIPPAHCKVKPNFPFLLFMRASEQM 420
Query: 421 DGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKA 480
DGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKA
Sbjct: 421 DGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKA 480
Query: 481 EAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTGPFFPV 540
EAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTGPFFPV
Sbjct: 481 EAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTGPFFPV 540
Query: 541 LSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSK 600
LSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSK
Sbjct: 541 LSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSK 600
Query: 601 DHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGR 660
DHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGR
Sbjct: 601 DHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGR 660
Query: 661 SLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNK 720
SLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNK
Sbjct: 661 SLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNK 720
Query: 721 SSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQD 780
SSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQD
Sbjct: 721 SSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQD 780
Query: 781 HGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEE 840
HGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEE
Sbjct: 781 HGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEE 840
Query: 841 EEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDR 900
EEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDR
Sbjct: 841 EEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDR 900
Query: 901 SRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRS 960
SRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRS
Sbjct: 901 SRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRS 960
Query: 961 RSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHS 1020
RSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHS
Sbjct: 961 RSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHS 1020
Query: 1021 GRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDC 1080
GRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDC
Sbjct: 1021 GRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDC 1080
Query: 1081 SPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLG 1140
SPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLG
Sbjct: 1081 SPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLG 1140
Query: 1141 NKPVLPLIGKLPATRKPNKKCEESGLERGEEQEQSETEEGPPGSSDALFGHQFPSEETTG 1200
NKPVLPLIGKLPATRKPNKKCEESGLERGEEQEQSETEEGPPGSSDALFGHQFPSEETTG
Sbjct: 1141 NKPVLPLIGKLPATRKPNKKCEESGLERGEEQEQSETEEGPPGSSDALFGHQFPSEETTG 1200
Query: 1201 PLLDPPPEESKSGEATADHPVAPLGTPAHSDCYPGDPTISHNYLPDPSDGDTLESLDSSS 1260
PLLDPPPEESKSGEATADHPVAPLGTPAHSDCYPGDPTISHNYLPDPSDGDTLESLDSSS
Sbjct: 1201 PLLDPPPEESKSGEATADHPVAPLGTPAHSDCYPGDPTISHNYLPDPSDGDTLESLDSSS 1260
Query: 1261 QPGPVESSLLPIAPDLEHFPSYAPPSGDPSIESTDGAEDASLAPLESQPITFTPEEMEKY 1320
QPGPVESSLLPIAPDLEHFPSYAPPSGDPSIESTDGAEDASLAPLESQPITFTPEEMEKY
Sbjct: 1261 QPGPVESSLLPIAPDLEHFPSYAPPSGDPSIESTDGAEDASLAPLESQPITFTPEEMEKY 1320
Query: 1321 SKLQQAAQQHIQQQLLAKQVKAFPASAALAPATPALQPIHIQQPATASATSITTVQHAIL 1380
SKLQQAAQQHIQQQLLAKQVKAFPASAALAPATPALQPIHIQQPATASATSITTVQHAIL
Sbjct: 1321 SKLQQAAQQHIQQQLLAKQVKAFPASAALAPATPALQPIHIQQPATASATSITTVQHAIL 1380
Query: 1381 QHHAAAAAAAIGIHPHPHPQPLAQVHHIPQPHLTPISLSHLTHSIIPGHPATFLASHPIH 1440
QHHAAAAAAAIGIHPHPHPQPLAQVHHIPQPHLTPISLSHLTHSIIPGHPATFLASHPIH
Sbjct: 1381 QHHAAAAAAAIGIHPHPHPQPLAQVHHIPQPHLTPISLSHLTHSIIPGHPATFLASHPIH 1440
Query: 1441 IIPASAIHPGPFTFHPVPHAALYPTLLAPRPAAAAATALHLHPLLHPIFSGQDLQHPPSH 1500
IIPASAIHPGPFTFHPVPHAALYPTLLAPRPAAAAATALHLHPLLHPIFSGQDLQHPPSH
Sbjct: 1441 IIPASAIHPGPFTFHPVPHAALYPTLLAPRPAAAAATALHLHPLLHPIFSGQDLQHPPSH 1500
Query: 1501 GT 1502
GT
Sbjct: 1501 GT 1502
>gi|34740327 zinc finger protein 804A [Homo sapiens]
Length = 1209
Score = 266 bits (680), Expect = 1e-70
Identities = 214/629 (34%), Positives = 308/629 (48%), Gaps = 86/629 (13%)
Query: 114 KYKDYVDKEKAIAKALEDLRANFYCELCDKQYQKHQEFDNHINSYDHAHKQRLKDLKQRE 173
K DY +KE IAKALEDL+ANFYCELCDKQY KHQEFDNHINSYDHAHKQRLK+LKQRE
Sbjct: 35 KTLDYAEKENTIAKALEDLKANFYCELCDKQYYKHQEFDNHINSYDHAHKQRLKELKQRE 94
Query: 174 FARNVSSRSRKDEKKQEKALRRLHELAEQRKQAECAPGSGPMFKPTTVAVDEEGGEDDKD 233
FARNV+S+SRKDE+KQEKAL+RLH+LAE RK+ CAPGSGPMFK TTV V E E +
Sbjct: 95 FARNVASKSRKDERKQEKALQRLHKLAELRKETVCAPGSGPMFKSTTVTVRENCNEISQR 154
Query: 234 ---ESATNSGTGATASCGLGSEFSTDKGGPFTAVQITNTTGLAQAPGLASQGISFGIKNN 290
+S N + SE +T + T +A+ P A+ ++ KNN
Sbjct: 155 VVVDSVNNQQDFKYTL--IHSEENT-----------KDATTVAEDPESAN---NYTAKNN 198
Query: 291 ------LGTPLQKLGVSFSFAKKAPVKLESIASVFKDHAEEGTSEDGTKPDEK--SSDQG 342
G K+G SF+F KKA VKLES A+ F +++++ + G + S
Sbjct: 199 QVGDQAQGIHRHKIGFSFAFPKKASVKLESSAAAFSEYSDDASVGKGFSRKSRFVPSACH 258
Query: 343 LQKVGDSDGSSNLDGKKEDEDPQDGGSLASTLSKLKRMKREEGAGATEPEYYHYIPPAHC 402
LQ+ +D + + K P + + + K + + E + P+ C
Sbjct: 259 LQQSSPTDVLLSSEEKTNSFHPPE------AMCRDKETVQTQEIKEVSSEKDALLLPSFC 312
Query: 403 KVKPNFPFLLFMRASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQ----GAEKTV 458
K + D DN + + S I + + G + TV
Sbjct: 313 K----------FQLQLSSDADNCQNSVPLADQIPLESVVINEDIPVSGNSFELLGNKSTV 362
Query: 459 SEVSEQ-PKETSMTEPSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETS 517
++S + TE + ++A + + + S++++V+ T K+T+
Sbjct: 363 LDMSNDCISVQATTEENVKHNEASTTEVENKNGPETLAPSNTEEVNIT------IHKKTN 416
Query: 518 LATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFK 577
K PF PVL+K ST LQWPSE+L++T +PSISYSCNPL FDFK
Sbjct: 417 FC-----------KRQCEPFVPVLNKHRSTVLQWPSEMLVYTTTKPSISYSCNPLCFDFK 465
Query: 578 LSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGS 637
++ + K KD+ S K + + G + K+V E + G +S +
Sbjct: 466 STKVNNNLDKNKPDLKDLCSQQKQ--EDICMGPLSDYKDVSTEGLTDYEIG-----SSKN 518
Query: 638 ACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRH--KKKKKHKKSSKHKRKHKADT 695
CS + S + K E +G+ +++ K ++ +K + K + K DT
Sbjct: 519 KCSQVTPLLADDILSSSCDS------GKNENTGQRYKNISCKIRETEKYNFTKSQIKQDT 572
Query: 696 -EEKSSKAESGEK-----SKKRKKRKRKK 718
+EK +K E K R+K+KRKK
Sbjct: 573 LDEKYNKIRLKETHEYWFHKSRRKKKRKK 601
Score = 107 bits (266), Expect = 1e-22
Identities = 74/194 (38%), Positives = 106/194 (54%), Gaps = 20/194 (10%)
Query: 1302 LAPLE--SQPITFTPEEMEKYSKLQQAAQQHI-QQQLLAKQVK-AFPASAALAPATPALQ 1357
LAPL Q + E +K+ + QHI Q +LA +VK FP +A P+TP LQ
Sbjct: 1024 LAPLALPEQALLIPLENHDKFKNVPCEVYQHILQPNMLANKVKFTFPPAALPPPSTP-LQ 1082
Query: 1358 PIHIQQPATASATSITTVQHAILQHHAAAAAAAIGIHP-------HPHPQPLAQVHHIPQ 1410
P+ +QQ + +TS+TT+ H +LQ HAAAAAAA PH Q L+Q+ + +
Sbjct: 1083 PLPLQQ--SLCSTSVTTIHHTVLQQHAAAAAAAAAAAAAGTFKVLQPHQQFLSQIPALTR 1140
Query: 1411 PHLTPISLSHLTHSIIPGHPATFLASHPIHIIPASAIHPGPFTFHPVPHAALYPTLLAPR 1470
L +S+ + + PG+ TF+A + IIPAS +HP F +PH AL+P+LL+P
Sbjct: 1141 TSLPQLSVGPVGPRLCPGNQPTFVAPPQMPIIPASVLHPSHLAFPSLPH-ALFPSLLSPH 1199
Query: 1471 PAAAAATALHLHPL 1484
P T + L PL
Sbjct: 1200 P-----TVIPLQPL 1208
>gi|31791053 zinc finger protein 804B [Homo sapiens]
Length = 1349
Score = 251 bits (640), Expect = 5e-66
Identities = 185/517 (35%), Positives = 255/517 (49%), Gaps = 61/517 (11%)
Query: 117 DYVDKEKAIAKALEDLRANFYCELCDKQYQKHQEFDNHINSYDHAHKQRLKDLKQREFAR 176
D+ +K K+ AKALED++ANFYCELCDKQY KHQEFDNHINSYDHAHKQRLK+LKQREFAR
Sbjct: 37 DFAEK-KSTAKALEDVKANFYCELCDKQYHKHQEFDNHINSYDHAHKQRLKELKQREFAR 95
Query: 177 NVSSRSRKDEKKQEKALRRLHELAEQRKQAECAPGSGPMFKPTTVAVDEEGGEDDKDESA 236
NV+S+S KDEKKQEKAL+RLH+LAE R+Q+EC G+GP +K VA++++ +
Sbjct: 96 NVASKSWKDEKKQEKALKRLHQLAELRQQSECVSGNGPAYKAPRVAIEKQ-----LQQGI 150
Query: 237 TNSGTGATASCGLGSEFSTDKGGPFTAVQITNTTGLAQAPGLASQGISFG-----IKNNL 291
G SC + K P +T + + + FG ++L
Sbjct: 151 FPIKNGRKVSCMKSALLLKGKNLPRIISDKQRSTMPNRHQLQSDRRCLFGNQVLQTSSDL 210
Query: 292 GTPLQKLGVSFSFAKKAPVKLESIASVFKDHAEEGTSEDGTKPDEKSSDQGLQKVGDSDG 351
+ GVSF+F+KK +KLES ASVF ++ EE T + P K+ +
Sbjct: 211 SNANHRTGVSFTFSKKVHLKLESSASVFSENTEE-THDCNKSPIYKTKQTADKCKCCRFA 269
Query: 352 SSNLDGKKEDEDPQDGGSLASTL-------SKLKRMKREEGAGATEPEYYHYIPPAHCKV 404
+ + KE E L S L SK+ + K + E I + K
Sbjct: 270 NKDTHLTKEKEVNISPSHLESVLHNTISINSKILQDKHDSIDETLEDSI--GIHASFSKS 327
Query: 405 KPNFPFLLFMRASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGA--------EK 456
+ + F S + + NT KN E +C+ A
Sbjct: 328 NIHLSDVDFTPTSREKETRNTL--KNTLE----------NCVNHPCQANASFSPPNIYNH 375
Query: 457 TVSEVSEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKET 516
+ + +SE E S EPSE S + +E+ + + +T+ N +
Sbjct: 376 SDARISECLDEFSSLEPSEQKSTVHLN-------PNSRIENREKSLDKTERVSKNVQRLV 428
Query: 517 SLATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDF 576
A S+ PF V SKD T LQWP+ELL+FTK EP ISY CNPLYFDF
Sbjct: 429 KEACTHNVASK------PLPFLHVQSKDGHTTLQWPTELLLFTKTEPCISYGCNPLYFDF 482
Query: 577 KLSRN-------KDARTKGTEKPKDIGSSSKDHLQGL 606
KLSRN +D +T+ +KP ++ + + + GL
Sbjct: 483 KLSRNTKEDHNLEDLKTELGKKPLELKTKRESQVSGL 519
Score = 201 bits (510), Expect = 6e-51
Identities = 180/651 (27%), Positives = 299/651 (45%), Gaps = 57/651 (8%)
Query: 878 SDQSCYSRQRSYSDDSYSDYSD-RSRRHSKRSHDSDDSD----YASSKHRSKRHK----- 927
S QSC SR S D S S S RS S R + + + + H +RHK
Sbjct: 700 SPQSCLSRYSSSLDTSPSSMSSLRSTCSSHRFNGNSRGNLLCFHKREHHSVERHKRKCLK 759
Query: 928 ---YSSSDDDYSLSCSQSRSRSRSHTR--ERSRSRGRSRSSSCSRSRSKRRSRSTTAHSW 982
+ SDD S QS + + + E ++ S+ C ++ ++ S
Sbjct: 760 HNCFYLSDDITKSSQMQSEPQKERNCKLWESFKNEKYSKRRYCHCRERQKLGKNQQQFSG 819
Query: 983 QRSRS--YSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQ----SP 1036
+S Y S+ + + S + + H+ + +S + + +K R+Q SP
Sbjct: 820 LKSTRIIYCDSNSQISCTGSSKKPPNCQGTQHDRLDS-YSIEKMYYLNKSKRNQESLGSP 878
Query: 1037 HYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLEK 1096
H G+ P K + G +N + G +E + + ++ +TAK+LLE+
Sbjct: 879 HICDLGKVR-PMKCNSGN------ISCLLKNCSSGPSETTESNTAEGERTPLTAKILLER 931
Query: 1097 IQSRKVERKPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLGNKPVLPLIGKLPATRK 1156
+Q++K + + S V+ + N +L+ P Q +L PS N+ LPL K+ +
Sbjct: 932 VQAKKCQEQ---SSNVEISSNSCKSELEAPSQVPCTIQLAPSGCNRQALPLSEKIQYASE 988
Query: 1157 PNKKCEESGLERGEEQEQSETEEGPPGSSDALFGHQFPSEETTG--PLLDPPPEESKSGE 1214
++ ++S + R E+++S++ + L + + G L+ + +
Sbjct: 989 -SRNDQDSAIPRTTEKDKSKSSH--TNNFTILADTDCDNHLSKGIIHLVTESQSLNIKRD 1045
Query: 1215 ATADHPVAPLGTPAHSDCYPGDPTISHNYLPDPSDGDTLESLDSSSQPGPVESSLLPIAP 1274
AT PL + DP + PS+ T + + +Q + L ++
Sbjct: 1046 ATTKEQSKPLISEIQPFIQSCDPVPNEFPGAFPSNKYTGVTDSTETQEDQINLDLQDVSM 1105
Query: 1275 DLEHFPSYAPPSGDPSIESTDGAEDA------SLAP-LESQPITFTPEEMEKYSKLQQAA 1327
+ H D +++ D ED S++P L QPITF+P+E++KY LQ A
Sbjct: 1106 HINHVEGNINSYYDRTMQKPDKVEDGLEMCHKSISPPLIQQPITFSPDEIDKYKILQLQA 1165
Query: 1328 QQHIQQQLLAKQVKAFPASA--ALAPATPALQPIHIQQPATASATSITTVQHAILQHHAA 1385
QQH+Q+QLL+K ++ PA+ A +PA+ +Q + + Q TSITT+ H LQH A
Sbjct: 1166 QQHMQKQLLSKHLRVLPAAGPTAFSPAS-TVQTVPVHQH-----TSITTIHHTFLQHFAV 1219
Query: 1386 AAAAAIGIHPHPHPQPLAQVHHIPQPHLTPISLSHLTHSIIPGHPATFLASHPIHIIPAS 1445
+A+ + H P+A +H + Q H +PIS S LT +IIP HP TFLA HP+H++ A+
Sbjct: 1220 SAS----LSSHSSHLPIAHLHPLSQAHFSPISFSTLTPTIIPAHP-TFLAGHPLHLVAAT 1274
Query: 1446 AIHPGPFTFHPVPHAALYPTLLAPRPAAAAATALHLHPLLHPIFSGQDLQH 1496
HP T P+P A PTL P A + +HL+PL+ P+F GQD H
Sbjct: 1275 PFHPSHITLQPLPPTAFIPTLFGPHLNPATTSIIHLNPLIQPVFQGQDFCH 1325
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 133 bits (335), Expect = 1e-30
Identities = 187/870 (21%), Positives = 295/870 (33%), Gaps = 50/870 (5%)
Query: 224 DEEGGEDDKD-ESATNSGTGATASCGLGSEFSTDKGGPFTAVQITNTTGLAQAPGLASQG 282
DE G DD + ES NS + AS G + ++ + S G
Sbjct: 469 DESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNG 528
Query: 283 ISFGIKNNLGTPLQKLGVSFSFAKKAPVKLESIASVFKDHAEEGTSEDGTKPDEKSSDQG 342
G N G S + + S +S D ++ +S+ + D SSD
Sbjct: 529 N--GNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSD 586
Query: 343 LQKVGDSDGS--SNLDGKKEDEDPQDGG-SLASTLSKLKRMKREEGAGATEPEYYHYIPP 399
DSD S SN + D D S S+ SK K E + ++
Sbjct: 587 SSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDS-------- 638
Query: 400 AHCKVKPNFPFLLFMRASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVS 459
K + +S+ D ++++ N+ +S SS S + +S ++ + S
Sbjct: 639 -----KSDSSDSNSSDSSDNSDSSDSSNSSNSSDS-SDSSDSSDSSSSSDSSNSSDSSDS 692
Query: 460 EVSEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLA 519
S E+S + S +++ + + SD + S + +S+ S ++S +
Sbjct: 693 SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNS 752
Query: 520 TPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLS 579
+ + S + S D S + S+ + + S + S + + S
Sbjct: 753 SDSSDSSDSSNSSDSSD-----SSDSSDS----SDSSNSSDSNDSSNSSDSSDSSNSSDS 803
Query: 580 RNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSAC 639
N + ++ S+S D D + + S + S D+ +S +
Sbjct: 804 SNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS---DSSDGSDSDSSNRSD 860
Query: 640 SGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKS 699
S + S S + D+ S S S S S + +D+ + S
Sbjct: 861 SSNSSDSSDSSDSSNSSDSSDS--SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS 918
Query: 700 SKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSL 759
+ ++S E S + +S+ + S S + +S S
Sbjct: 919 NSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSD 978
Query: 760 PAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDED 819
+ S + S S D + SS + +S S S SS D
Sbjct: 979 SSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSD 1038
Query: 820 SDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSD 879
S D+S S + + + S S S S S S SS S SS+S SSD
Sbjct: 1039 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSD 1098
Query: 880 QSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDD--DYSL 937
S S SD S S S S S S SD SD + S + S S S D D S
Sbjct: 1099 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSD 1158
Query: 938 SCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTR 997
S S S S + + S S S SS S S S ++ S S S D S S+
Sbjct: 1159 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1218
Query: 998 SPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDD 1057
S S S S S +ES + S S S S D D
Sbjct: 1219 S-SDSSDSSDSSDSNESSDSSDS------------SDSSDSSNSSDSSDSSDSSDSTSDS 1265
Query: 1058 SKATGPPSQNSNIGTGRGSEGDCSPEDKNS 1087
+ + S++ N G GS+ D E +S
Sbjct: 1266 NDESDSQSKSGN-GNNNGSDSDSDSEGSDS 1294
Score = 117 bits (292), Expect = 1e-25
Identities = 207/965 (21%), Positives = 323/965 (33%), Gaps = 104/965 (10%)
Query: 178 VSSRSRKDEKKQEKALRRLHELAEQRKQAECAPGSGPMF-------KPTTVAVDE---EG 227
+ S ++E + +++ K+AE PG+G P+ DE EG
Sbjct: 199 IIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEG 258
Query: 228 GEDDKDESATNSGTGATASCGL-GSEFSTDKGGPFTAVQITNTTGLAQAPG-------LA 279
DD+DE A N + S G G + + + Q +++ G +
Sbjct: 259 SGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVD 318
Query: 280 SQGISFGIKNNLGTPLQKLGVSFSFAKKAPVKLESIASVFKDHAEEGTSEDGTKPDEKSS 339
S +N+ G P +K + ES K T E T KS
Sbjct: 319 GDKTSKSEENSAGIPEDNGSQRIEDTQKLNHR-ES-----KRVENRITKESETHAVGKSQ 372
Query: 340 DQGLQKVGDSDGSSNLDGK--KEDEDPQDGGSLASTLSKLKRMKREEGAGATEP----EY 393
D+G++ G S G+ N+ + K +E +D G L K + E P E
Sbjct: 373 DKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEP 432
Query: 394 YHYIPPAHCKVKPN---FPFLLFMRASEQMDGDNTTHPKNAPE----------SKKG--- 437
+ + ++ N + F S Q D N++ N + S +G
Sbjct: 433 GNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDAS 492
Query: 438 -SSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKKALG--------G 488
+S + K + S+GAE S+ + + G+ K G
Sbjct: 493 YNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDS 552
Query: 489 DVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTGPFFPVLSKDESTA 548
D SD S S S S++ +SNSS ++ + +S + S D S +
Sbjct: 553 DSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSD-----------SSDSSNS 601
Query: 549 LQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDP 608
+ + S S + D S++ ++++ D S S D D
Sbjct: 602 ----------SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDS-NSSDS 650
Query: 609 GEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPG----GSHGSETEDTGRSLPS 664
+ + S + S D+ S S+ N + S+ SE+ D+ S S
Sbjct: 651 SDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDS 710
Query: 665 KKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAP 724
S S + SS + +D+ + S+ ++S + S + SS
Sbjct: 711 DSSDSSDS-------SNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS--------SNSSDS 755
Query: 725 ADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGR 784
+DS S + DS S ++ S + S S D
Sbjct: 756 SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDS 815
Query: 785 KHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEED 844
S + + SS SS S S + SD SS+R + S S+ + +
Sbjct: 816 SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSN 875
Query: 845 SG-SEHSRSRSRSGRRHSSHRSSRRSYSSSSDA--SSDQSCYSRQRSYSDDSYSDYSDRS 901
S S S + S S SS S S SSD+ SSD S S S+ S S + S
Sbjct: 876 SSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNS 935
Query: 902 RRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSR 961
S S SD SD ++S S +SSD S S S S S + S S S
Sbjct: 936 SDSSNSSDSSDSSDSSNSSDSS-----NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSD 990
Query: 962 SSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSG 1021
SS S S S ++ S S S D S S+ S + S S S
Sbjct: 991 SSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSD 1050
Query: 1022 RRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCS 1081
D S S S + D DS + S +S+ S
Sbjct: 1051 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSD 1110
Query: 1082 PEDKN 1086
D +
Sbjct: 1111 SSDSS 1115
Score = 96.3 bits (238), Expect = 2e-19
Identities = 131/715 (18%), Positives = 241/715 (33%), Gaps = 27/715 (3%)
Query: 224 DEEGGEDDKDESATNSGTGATASCGLGSEFSTDKGGPFTAVQITNTTGLAQAPGLASQGI 283
D D D S + S + + S S+ +D ++ N+ + S
Sbjct: 609 DSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDS 668
Query: 284 SFGIKNNLGTPLQKLGVSFSFAKKAPVKLESIASVFKDHAEEGTSEDGTKPDEKSSDQGL 343
S ++ + S + + S +S D ++ +S+ + SSD
Sbjct: 669 SDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDS 728
Query: 344 QKVGDSDGSSNLDGKKEDEDPQDGGSLASTLSKLKRMKREEGAGATEPEYYHYIPPAHCK 403
DS SSN + D + + + + + +++ ++
Sbjct: 729 SNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDS 788
Query: 404 VKPNFPFLLFMRASEQMDGDNTTHPKNAPESKKGS----SPKPKSCIKAAASQGAEKTVS 459
+S+ D N++ N+ +S S S S + +S ++ + S
Sbjct: 789 ----------SNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS 838
Query: 460 EVSEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLA 519
S ++S S+ +++++ + D SD S S+S S++ +S+ S
Sbjct: 839 SDSSDSSDSSDGSDSDSSNRSDSSNS--SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSD 896
Query: 520 TPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLS 579
+ +S + + +S+ S+ + + S S + + S
Sbjct: 897 SSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDS 956
Query: 580 RNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAP-ASGSA 638
N + ++ S S D D + + S + +S D+ +S S+
Sbjct: 957 SNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1016
Query: 639 CSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEK 698
S + S+ S++ D+ S S + S S S +D+ +
Sbjct: 1017 NSSDSSNSSDSSNSSDSSDSSDSSDSS-DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1075
Query: 699 SSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRS 758
S ++S E S + SS +DS S + DS S
Sbjct: 1076 SDSSDSSESSDSSDSSN--SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1133
Query: 759 LPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDE 818
++ +S + S S D + SS + +S S S SS
Sbjct: 1134 DSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1193
Query: 819 DSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASS 878
DS D+S S + + S S S S S S SS S SS+S SS
Sbjct: 1194 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSS 1253
Query: 879 DQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDD 933
D S S DS SD +D S SK + +++ + S +S+SDD
Sbjct: 1254 DS-------SDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 94.4 bits (233), Expect = 8e-19
Identities = 124/553 (22%), Positives = 205/553 (37%), Gaps = 65/553 (11%)
Query: 583 DARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPA-SGSACSG 641
+++ GT++ + + +D GLD + + S E SG D A +G S
Sbjct: 218 NSKRNGTKEAEVTPGTGED--AGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSN 275
Query: 642 LNKQEPGGSHGSETE---DTGRSLPSKK--ERSGKSHRHKKKKKHKKSSKHKRKHKADTE 696
+K + G HG E + G++ SK+ + GK H + K S + +
Sbjct: 276 NSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPED 335
Query: 697 EKSSKAESGEK-----SKKRKKRKRKKNKSSAPADSE-RGPKPEPPGSGSPAPPR---RR 747
S + E +K SK+ + R K++++ A S+ +G + + P SG+ + +
Sbjct: 336 NGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKG 395
Query: 748 RRAQDDSQRRSL------------------PAEEGSSGKK--------DEGGGGSSSQDH 781
++D + + P ++ G K D G S D
Sbjct: 396 NEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDF 455
Query: 782 GGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEE 841
+ +G+ P SS + +S S + S S GD + S S S+ +E+++
Sbjct: 456 DDKSMQGDDPNSSDESNGNDDANSESDNNSS-SRGDASYNSDESKDNGNGSDSKGAEDDD 514
Query: 842 EE---DSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYS 898
+ D+ + S +G + S + S SSD+ S S S SD S SD S
Sbjct: 515 SDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDS--SNSSDSSDSSDSDSS 572
Query: 899 DRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSD----DDYSLSCSQSRSRSRSHTRERS 954
D + S DSD SD + S + SSD D S S S S+S S E
Sbjct: 573 DSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632
Query: 955 RSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHES 1014
S S+S S + S S ++ S S S S + S S S S +S
Sbjct: 633 SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692
Query: 1015 PEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGR 1074
+ +S S+S S + D + S + S +S+ +
Sbjct: 693 SDSSNS------------SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS 740
Query: 1075 GSEGDCSPEDKNS 1087
D S +S
Sbjct: 741 SDSSDSSDSSNSS 753
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 114 bits (286), Expect = 5e-25
Identities = 186/814 (22%), Positives = 294/814 (36%), Gaps = 75/814 (9%)
Query: 288 KNNLGTPLQ-----KLGVSFSFAKKAPVKLESIASVFKDHAEEGTSEDGTKPDEKSSDQG 342
+N+ G+PL+ LG + + VK E + F + E T P +Q
Sbjct: 1324 ENSFGSPLEFRNSGPLGTEMNTGFSSEVK-EDLNGPFLNQLE-------TDPSLDMKEQS 1375
Query: 343 LQKVGDSDGSSNLDGKKEDEDPQDGGSLASTLSKLKRM-KREEGAGATEPEYYHYIP--P 399
+ G S + D ++ + + L + R RE + A+ PE +P P
Sbjct: 1376 TRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTP 1435
Query: 400 AHCKVKPNFPFLLFMRASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVS 459
+ + P L DG T + S GSSP K I S+G S
Sbjct: 1436 SRRSRSGSSPGL--------RDGSGTP----SRHSLSGSSPGMKD-IPRTPSRGR----S 1478
Query: 460 EVSEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLA 519
E P+ ++ + P S++ + L E ES+ ++T
Sbjct: 1479 ECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGS--------ESSVDQKTVAR 1530
Query: 520 TPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLS 579
TP G+ S+ G L S + Q SE + S + + PL +
Sbjct: 1531 TPLGQRSRSGSSQE-------LDVKPSASPQERSES---DSSPDSKAKTRTPLRQRSRSG 1580
Query: 580 RNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSAC 639
+ + +K P+ S S ++ P ++ R S S
Sbjct: 1581 SSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGS 1640
Query: 640 SGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKS 699
S +K GS + ++ P K + + R + K K + +R+ + E +
Sbjct: 1641 S--SKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELT 1698
Query: 700 SKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSL 759
KA +S R + +S P R P P + RRRR+ + ++
Sbjct: 1699 RKARLSRRS--RSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTT 1756
Query: 760 PAEEGSSGKKDEGGGGSSSQDHGG------RKHKGELPPSSCQRRAGTKRSSRSSHRSQP 813
S K G S S+ R+ + S+ +RR ++ SR + R +
Sbjct: 1757 SRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRG 1816
Query: 814 SSG-------DEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSS 866
SG ++S SS R +S + + + S RSRS ++HR S
Sbjct: 1817 GSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRS 1876
Query: 867 RRSYS--SSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSK 924
R S + S S SR+RS S S + RSR S ++ RS+
Sbjct: 1877 RSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSR 1936
Query: 925 RHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSK-RRSRSTTAHSWQ 983
++ S + +R RSRS T +R R RSR+S +R RS+ R S T S
Sbjct: 1937 SRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRS 1996
Query: 984 RSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGR 1043
R+ +R RSRS SP R SR R+ + R R + K RS+SP R R
Sbjct: 1997 RTSPVTRRRSRSRTSPVTRRRSRSRT--PPAIRRRSRSRTPLLPRKRSRSRSPLAIR--R 2052
Query: 1044 GEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSE 1077
RG S PP+ +G S+
Sbjct: 2053 RSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSD 2086
Score = 112 bits (279), Expect = 4e-24
Identities = 316/1430 (22%), Positives = 477/1430 (33%), Gaps = 225/1430 (15%)
Query: 229 EDDKDESATNSGTGATASCGLGSEFSTDKGGPFTAVQITNTTGLAQ-APGLASQGISFGI 287
++ +S S G+ + C G + ST G + V G +Q +P S S +
Sbjct: 1018 QEKSKDSLVQSCPGSLSLCA-GVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEV 1076
Query: 288 KNNLGTPLQKLGVSFSFAKKAPVKLESIASVFKDHAEEGTSEDGTKPDE-KSSDQGLQKV 346
+ Q S S K+ + S E S + D + S + K
Sbjct: 1077 R-------QSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKS 1129
Query: 347 GDSDGSSNLDGKKEDEDPQDGGSLASTLSKLKRMKREEGAGATEPEYYHYIPPAHCKVKP 406
G S S D SL S+L+ + +E E PP + K
Sbjct: 1130 GMSPEQSRFQSDSSSYPTVDSNSLLGQ-SRLETAESKEKMALPPQEDATASPP---RQKD 1185
Query: 407 NF-PFLLFMRASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQP 465
F PF + R + +T S GSSP+ K A + ++ + EV E+
Sbjct: 1186 KFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKS 1245
Query: 466 KETS--------------MTEPSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCES- 510
+E + T E + E + A+ + ++ + V M S
Sbjct: 1246 EEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSW 1305
Query: 511 ----------------------NSSKETSLATPAGKE-----SQEGPKHPTGPFFPVLSK 543
S E + P G E S E + GPF L
Sbjct: 1306 GGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLET 1365
Query: 544 DESTALQ-----------------------------WPSELLIFTKAEPSISYSCNPLYF 574
D S ++ S +L PS S +
Sbjct: 1366 DPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSP 1425
Query: 575 DFK--LSRNKDARTKGTEKP---KDIGSSSKDHLQGLDPG-------------EPNKSKE 616
+ K L R R++ P G+ S+ L G PG E + S E
Sbjct: 1426 EMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPE 1485
Query: 617 VGG-EKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHR- 674
+ R +P + C ++ G + + R+ ++ RSG S
Sbjct: 1486 PKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQEL 1545
Query: 675 -------HKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAP--- 724
+++ + S K K + ++S S E K + R+ S+P
Sbjct: 1546 DVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVK 1605
Query: 725 --------ADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGS 776
A S PEP A PRR R R P S+ E S
Sbjct: 1606 DKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKS 1665
Query: 777 SSQDHGGR-----KHKGELPPSSCQRRAGTK--RSSRSSHRSQPSSGDEDSDDASSHRLH 829
+ G R K K PP R+ + R +R S RS+ +S ++ + R H
Sbjct: 1666 RTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPR-H 1724
Query: 830 QKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSY 889
++SPS S E E+ S RS S + +S R RS S SR+
Sbjct: 1725 RRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRG--RSPSPKPRGLQRSRSRSRREKT 1782
Query: 890 SDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHR--SKRHKYSSSDDDYSLSCSQSRSRSR 947
D S S+ S+R S + + R S H S + + S + S+ R R R
Sbjct: 1783 RTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSR-RRRGR 1841
Query: 948 SHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRS--YSRDRSRSTRSP------ 999
S T SR R RSR+S RS+ R+ S H RSR+ SR RSRS SP
Sbjct: 1842 SRTPPTSRKRSRSRTSPAPWKRSRSRA-SPATHRRSRSRTPLISRRRSRSRTSPVSRRRS 1900
Query: 1000 -SQRSGSRKRSWGHESP--EERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGD 1056
S+ S +R+RS SP R R + + RS++P R R P
Sbjct: 1901 RSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTP----PVTRR 1956
Query: 1057 DSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATP 1116
S++ PP T R S SP + + ++ V R+ S S T
Sbjct: 1957 RSRSRTPPV------TRRRSRSRTSPITRRR-------SRSRTSPVTRRRSRSRTSPVTR 2003
Query: 1117 NKAGPKLKDPPQGYFGPKLPPSLGNK-----PVLPLIGKLPATRKP--NKKCEESGLERG 1169
++ + + + PP++ + P+LP K +R P ++ S R
Sbjct: 2004 RRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLP--RKRSRSRSPLAIRRRSRSRTPRT 2061
Query: 1170 EEQEQSETEEGPPGSSDALFGHQFPSEETTGPLLDPPPEESKSGEATADHPVAPLGTPAH 1229
++S T P + G S PP + SG T PVA +
Sbjct: 2062 ARGKRSLTRSPPAIRRRSASG----SSSDRSRSATPPATRNHSGSRTP--PVAL--NSSR 2113
Query: 1230 SDCYPGDPTISHNYLPDPSDGDTLESLDSSSQP--------GPVESSLLPIAPDLEHFPS 1281
C+ P++S L LE L SS P G + P PD H +
Sbjct: 2114 MSCF-SRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPD--HQRT 2170
Query: 1282 YAPPSGDPS-------------IESTDGAEDASLAPLESQPITFTPEEMEKYSKLQQAAQ 1328
P + S A LA SQ P L+ A
Sbjct: 2171 SVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVP-----LMSLRTAPA 2225
Query: 1329 QHIQQQLLAKQVKAFPASAALAPATP-ALQPIHIQQPATASATSITTVQHAILQHHAAAA 1387
++ ++ A A ++A PA P A+ + PA A+A ++ + + A+ A
Sbjct: 2226 ANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAV------AP 2279
Query: 1388 AAAIGIHPHPHPQPLAQVHHIPQPHLTPISLSHLTHSIIPGHPATFLASHPIHIIPASAI 1447
+A P P + P ++ LT S P A + +S PASA
Sbjct: 2280 SAVNLADPRTPTAPAVNLAGARTP--AALAALSLTGSGTPPTAANYPSSSRTPQAPASAN 2337
Query: 1448 HPGPFTFHPVPHAALYPTLLAPRPAAAAATALHLHPLLHPIFSGQDLQHP 1497
GP + HA + R AAA A A + P SG +L P
Sbjct: 2338 LVGPRS----AHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSP 2383
Score = 111 bits (277), Expect = 6e-24
Identities = 137/566 (24%), Positives = 214/566 (37%), Gaps = 48/566 (8%)
Query: 593 KDIGSSSKDHLQGLDPG--EPNKSKEVGGEKI--VRSSGGRMDAPASGSACSGLNKQEPG 648
KD+ K+ G P E ++ E+ +K +R++ G D+ GS+ +
Sbjct: 101 KDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREA 160
Query: 649 GSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKS 708
E + ++ S +S K+KKK KK + +R + + K+ +K
Sbjct: 161 KQPAPEPPKPYSLV--RESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKH 218
Query: 709 KKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGK 768
+ + K++K++S P + + S S P + RRA + S + + S +
Sbjct: 219 RSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSR 278
Query: 769 KDEGG--------GGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDS 820
G S GR+ +G+ P S + + SS + QPSS ED
Sbjct: 279 SRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDK 338
Query: 821 DDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRS-------SRRSYSSS 873
D +KS ++ S E +G E RH S+ +
Sbjct: 339 DKDKK----EKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPP 394
Query: 874 SDAS--SDQSCYSRQRSYSDDSYSDYSDRS------RRHSKRSHDSDDSDYASSKHR--- 922
S+AS D+S S S+ S S RH+ S +S A HR
Sbjct: 395 SEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREIS 454
Query: 923 ------SKRHKYSSSDDDYSLSCSQSRSRSRS-HTRERSRSRGRSRSS-SCSRSRSKRRS 974
++ H + D +S + S+ RSRS T +R RSR R+ + SRSRS +
Sbjct: 455 SSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWR 514
Query: 975 RSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQ 1034
RS +A W RSRS R R RS RSP + SR R+ R RS R +
Sbjct: 515 RSRSAQRWGRSRSPQR-RGRS-RSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGR 572
Query: 1035 SPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLL 1094
S + RG + R S+ S RG +P + S T +
Sbjct: 573 SRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVR 632
Query: 1095 EKIQSRKVERKPSVSEEVQATPNKAG 1120
+ +SR R+ S TP + G
Sbjct: 633 RRSRSRSPARRSGRSR--SRTPARRG 656
Score = 110 bits (274), Expect = 1e-23
Identities = 210/882 (23%), Positives = 317/882 (35%), Gaps = 135/882 (15%)
Query: 428 PKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKKALG 487
PK+ +SK + +S A S+ A ++ S S +TS + +K G
Sbjct: 234 PKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG 293
Query: 488 GDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTGPF--FPVLSKDE 545
S S + + E + TS P+ E+ K P+ P+ K++
Sbjct: 294 ---RSPSPASGRRGEGDAPFSEPGT---TSTQRPSSPET--ATKQPSSPYEDKDKDKKEK 345
Query: 546 STALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQG 605
S PS T EP + PL + R G+ +P S++ +
Sbjct: 346 SATRPSPSPERSSTGPEPP---APTPLLAE---------RHGGSPQPLATTPLSQEPVNP 393
Query: 606 LDPGEP--NKSKEVGGEKIVRSSGGRMDAPA------SGSACSGLNKQEPGGSHGSETED 657
P ++S EK+ +SS P+ S A S +P + GS E
Sbjct: 394 PSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREI 453
Query: 658 TGRSLPSKKERS------GKSHRHKKKKKHKKS----SKHKRKHKADTEEKSSKAESGEK 707
+ S P+ K RS KSH H ++ +S + + + ++ T K + S
Sbjct: 454 S--SSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSP 511
Query: 708 SKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSG 767
+R + ++ +S +P R P+ PG +RR R++ + RS + G
Sbjct: 512 QWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRG 571
Query: 768 KKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHR 827
+ S S+ R P+ + R+ T RS R+ G S + R
Sbjct: 572 R-------SRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRR 624
Query: 828 LHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQR 887
+SP + RSRSRS R S SR S + R R
Sbjct: 625 SRTRSPVR--------------RRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSR 670
Query: 888 SYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRS--- 944
S + R S RS + S+ R+ R S+SRS
Sbjct: 671 SRT----------PARRSGRSRSRTPARRGRSRSRTPRR-----------GRSRSRSLVR 709
Query: 945 RSRSHTRERSRSRGRSRSSSCSRSRSK---RRSRSTTAHSWQRSRSYSRDRSRSTRSPSQ 1001
R RSH+R R RGRS SSS +++S+ RRSRS ++ ++SR SR RSRS SP
Sbjct: 710 RGRSHSRTPQR-RGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSR-RSRSLSSPRS 767
Query: 1002 RSGSR---KRSWGHESPEERHSGRRDFIRSKIYRSQ-------SPHYFRSGRGEGPGKKD 1051
++ SR +RS SP + + RS+ SQ P RS P +K
Sbjct: 768 KAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKS 827
Query: 1052 DGRGDDSKATGPPSQNSNIGTGRGSEGDCSPE-DKNSVTAKLLLEKIQSRKVERKPSVSE 1110
S ++ P GT SP+ ++ SVT Q R E
Sbjct: 828 KTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTP-------QRRSCFESSPDPE 880
Query: 1111 EVQATPNKAGPKLKDPP--QGYFGPKLPPSLGNKPVLPLIGKLPATRKPNKKCEESGLER 1168
TP++ PP + P+ PS + P K+ A P ++
Sbjct: 881 LKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQ----PKVKAIISPRQRSHSGSSSP 936
Query: 1169 GEEQEQSETEEGPPGSSDALFGHQFPSEETTGPLLDPPPEESKSGEATADHPVAPLGTP- 1227
+ S T P S ++ P LL P S SG ++ D V P P
Sbjct: 937 SPSRVTSRT---TPRRSRSV----SPCSNVESRLL---PRYSHSGSSSPDTKVKPETPPR 986
Query: 1228 -AHSDCYPGDPTISHNYLPDPSDGDTLESLDSSSQPGPVESS 1268
+HS P + P P SL S P P E S
Sbjct: 987 QSHSGSISPYPKVKAQTPPGP-------SLSGSKSPCPQEKS 1021
Score = 105 bits (263), Expect = 3e-22
Identities = 204/903 (22%), Positives = 314/903 (34%), Gaps = 143/903 (15%)
Query: 580 RNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSAC 639
R ++A+ E PK S ++ P K K+ ++ RS S S
Sbjct: 156 RAREAKQPAPEPPKPY-SLVRESSSSRSPTPKQKKKKKKKDRGRRSE--------SSSPR 206
Query: 640 SGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKS 699
K H SE+E R S +S + + KK+K+ + ++ + +A +
Sbjct: 207 RERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSA 266
Query: 700 SKAESGEKSKKRKKRKRKKN-------KSSAPADSERGPKPEPPGSGSPAPPRRRRRAQD 752
A S + S+ R + K +S +PA RG P +R +
Sbjct: 267 DSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPET 326
Query: 753 DSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSS----CQRRAGTKRSSRSS 808
+++ S P E+ KK++ S R G PP+ +R G+ + ++
Sbjct: 327 ATKQPSSPYEDKDKDKKEKSATRPSPSPE--RSSTGPEPPAPTPLLAERHGGSPQPLATT 384
Query: 809 HRSQ-----PSSGDEDSDDA---SSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGR-- 858
SQ PS D + S +L Q S S+ S + S H+ S S +
Sbjct: 385 PLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPA 444
Query: 859 -RHSSHR-------SSRRSYSSSSDASSDQSCYSRQ--RSYSDDSYSDYSDRSRRHSKRS 908
SHR S RS+ + S SR+ RS S + RSR +KR
Sbjct: 445 PAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRG 504
Query: 909 HDSDDSD----------YASSKHRSKRHK--------YSSSDDDYSLSCSQSRSRSRSH- 949
H S + S+ +R + +S S + S+S R RSH
Sbjct: 505 HSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHS 564
Query: 950 ----TRERSRSR-----GRSRSSSCSRSRS------KRRSRSTTAHSWQRSRSYSRDRSR 994
TR RSRSR GRSRS + +R RS +RRSRS T RSRS + R R
Sbjct: 565 RSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRR 624
Query: 995 S-----------TRSPSQRSG-----------------------SRKRSWGHES--PEER 1018
S +RSP++RSG SR R+ S R
Sbjct: 625 SRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSR 684
Query: 1019 HSGRRDFIRSKI---YRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRG 1075
RR RS+ RS+S R GR + GR S S+ S R
Sbjct: 685 TPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQ----RR 740
Query: 1076 SEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKD---PPQGYFG 1132
S + SPE K S + + S + + K +S + + PK K P + G
Sbjct: 741 SRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSG 800
Query: 1133 PKLPPSLGNKPVLPLIGKLPATRKPNKKCE-ESGLERGEEQEQSETEEGPPGSSDALFGH 1191
P + P P + ++ P +K + S + + G P ++
Sbjct: 801 SSQPKAKSRTP--PRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSP 858
Query: 1192 QFPSEETTGPLLDPPPEESKSGEATADHPVAPLGTPAHSDCYPGDPTISHNYLPDPSDGD 1251
Q + T P+ E++ D P TP+ C P + P
Sbjct: 859 QANEQSVT-------PQRRSCFESSPD-PELKSRTPSRHSCSGSSPPRVKSSTP------ 904
Query: 1252 TLESLDSSSQPGPVESSLLPIAPDLEHFPSYAPPSGDPSIESTDGAEDASLAPLESQPIT 1311
+S SS P P ++ I+P + PS T S++P +
Sbjct: 905 PRQSPSRSSSPQPKVKAI--ISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESR 962
Query: 1312 FTPEEMEKYSKL--QQAAQQHIQQQLLAKQVKAFPASAALAPATPALQPIHIQQPATASA 1369
P S + + +Q + + +P A P P+L P S
Sbjct: 963 LLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSK 1022
Query: 1370 TSI 1372
S+
Sbjct: 1023 DSL 1025
Score = 59.7 bits (143), Expect = 2e-08
Identities = 97/362 (26%), Positives = 123/362 (33%), Gaps = 69/362 (19%)
Query: 704 SGEKSKKRKKRKRKKNKSSAPADS----ERGPKPE------------PPGSGSPAPPRRR 747
SG S R R + SAP+ S ER P P PP P P
Sbjct: 2394 SGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPS 2453
Query: 748 RRAQDDSQRRSLPAEEGSSGKKDEGGGG-----SSSQDHGG----------RKHKGELPP 792
A D R + +G + G SS+ DH G GE P
Sbjct: 2454 --AFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPA 2511
Query: 793 SSCQRR---------AGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKS----------- 832
S+ ++ A +RSS SS S SS S +SS S
Sbjct: 2512 STGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQ 2571
Query: 833 --------PSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYS 884
PS +E G + ++ RR SS SS S SSSS +SS S S
Sbjct: 2572 PEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSS 2631
Query: 885 RQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSK-------HRSKRHKYSSSDDDYSL 937
S S S S S S +K + + K RS R S D SL
Sbjct: 2632 SSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSL 2691
Query: 938 SCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTR 997
S S R R + R + S S SR + SRS + + + S R RS+R
Sbjct: 2692 SYSPVERR-RPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSR 2750
Query: 998 SP 999
SP
Sbjct: 2751 SP 2752
Score = 55.8 bits (133), Expect = 3e-07
Identities = 62/245 (25%), Positives = 93/245 (37%), Gaps = 21/245 (8%)
Query: 590 EKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGG 649
E P G+ L L P + +S SS + +S S+ S + E G
Sbjct: 2508 EPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE-GS 2566
Query: 650 SHGSETEDTGRSLPSKKERSGKSHRH--------KKKKKHKKSSKHKRKHKADTEEKSSK 701
S + E + +PS ++ R K+K+ SS + + SS
Sbjct: 2567 SLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSS 2626
Query: 702 AESGEKSKKRKKRKRKKNKSSAPADSERGPK--PEPPGSGSPAPPRRRRRAQD---DSQR 756
+ S S + SS+P+ ++ GP+ P+P P P RR R+ DS R
Sbjct: 2627 SSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLR 2686
Query: 757 --RSL---PAE-EGSSGKKDEGGGGSSSQDHGGRK-HKGELPPSSCQRRAGTKRSSRSSH 809
RSL P E S + SSS + G R+ +G+ S +RR T H
Sbjct: 2687 DSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRH 2746
Query: 810 RSQPS 814
RS S
Sbjct: 2747 RSSRS 2751
Score = 48.5 bits (114), Expect = 5e-05
Identities = 199/986 (20%), Positives = 330/986 (33%), Gaps = 139/986 (14%)
Query: 415 RASEQMDGDNTTHPKNAPESKKG--------SSPKPKSCIKAAASQGAEKTVSEVSEQPK 466
R ++ + ++PE KK S P+S KA + +++S S PK
Sbjct: 730 RKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRS--KAKSRLSLRRSLSGSSPCPK 787
Query: 467 ETSMTEPSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKES 526
+ S T P S + KA +S S S + S S +S P K
Sbjct: 788 QKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVK-- 845
Query: 527 QEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDART 586
G G + ++S Q SC F+ S + + ++
Sbjct: 846 -SGTPPRQGSITSPQANEQSVTPQ---------------RRSC------FESSPDPELKS 883
Query: 587 KGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQE 646
+ T SS ++ P + S RSS + P + S +
Sbjct: 884 R-TPSRHSCSGSSPPRVKSSTPPRQSPS---------RSSSPQ---PKVKAIISPRQRSH 930
Query: 647 PGGSHGSETEDTGRSLPSKKER----SGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKA 702
G S S + T R+ P + S R + H SS K K +T + S +
Sbjct: 931 SGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHS 990
Query: 703 ESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAE 762
S K K ++ P P GS SP P + + DS +S P
Sbjct: 991 GSISPYPKVK--------------AQTPPGPSLSGSKSPCPQEKSK----DSLVQSCP-- 1030
Query: 763 EGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDD 822
G G SS G + SS Q + ++ S HRS SS +
Sbjct: 1031 ----GSLSLCAGVKSSTPPG----ESYFGVSSLQLKGQSQTS--PDHRSDTSSPE----- 1075
Query: 823 ASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSS----SDASS 878
+ H +SPS S+ + G S S S R R +S+S S S
Sbjct: 1076 --VRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSP 1133
Query: 879 DQSCY-SRQRSYSDDSYSDYSDRSRRHSKRSHDS----DDSDYASSKHRSKRHKYSSSDD 933
+QS + S SY + +SR + S + D +S R K D
Sbjct: 1134 EQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQK--------D 1185
Query: 934 DYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRS--TTAHSWQRSRSYSRD 991
+S Q R S ++ R+ R RS + S +K ++ + T++ + +
Sbjct: 1186 KFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKS 1245
Query: 992 RSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQS---------PHYFRSG 1042
+ + S S K R + + +SQS P S
Sbjct: 1246 EEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSW 1305
Query: 1043 RGE--GPGKKDDGRGD-DSKATGPPSQNSNIG-TGRGSEGDCSPEDKNSVTAKLLLEKIQ 1098
G P K+ + G P + N G G S E K + L
Sbjct: 1306 GGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFL----- 1360
Query: 1099 SRKVERKPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLGNKPVLPLIGKLPATRKPN 1158
++E PS+ + Q+T + + P K S P++ +P T
Sbjct: 1361 -NQLETDPSLDMKEQSTRSSGHSSSELSPDAV--EKAGMSSNQSISSPVLDAVPRTPSRE 1417
Query: 1159 KKCEESGLERGEEQEQSETEEGPPGSSDAL-FGHQFPSEET---TGPLLDPPPEESKSGE 1214
+ S E + ++ + GSS L G PS + + P + P G
Sbjct: 1418 RSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGR 1477
Query: 1215 ATAD---HPVAPLGTPAHSDCYPGDPTISHNYL-PDPSDGDTLESLDSS--SQPGPVESS 1268
+ D P A TP P P +++ L P + S+D ++ + S
Sbjct: 1478 SECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRS 1537
Query: 1269 LLPIAPDLEHFPSYAPPSGDPSIESTDGAEDASLAPLESQPITFTPEEMEKYSKLQQAAQ 1328
+ +L+ PS +P S S D ++ + PL + + + E++ S+L
Sbjct: 1538 RSGSSQELDVKPSASPQERSESDSSPD-SKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRS 1596
Query: 1329 QHIQQQLLAKQVKAFPASAALAPATP 1354
+ + + +A P + + + ++P
Sbjct: 1597 RSGSSPEVKDKPRAAPRAQSGSDSSP 1622
Score = 46.2 bits (108), Expect = 2e-04
Identities = 59/274 (21%), Positives = 87/274 (31%), Gaps = 55/274 (20%)
Query: 628 GRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKH 687
G + PA G S + EP S G++ +L KER
Sbjct: 2492 GMLSVPAPGVPHSDVG--EPPASTGAQQPSALAALQPAKER------------------- 2530
Query: 688 KRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADS----------ERGPKPEPPG 737
++ + SS + S S + SS S +R P P P
Sbjct: 2531 ----RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAP 2586
Query: 738 SGS--------PAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGE 789
+ P P +R+RR+ S S + SS SSS
Sbjct: 2587 KEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2646
Query: 790 LPPSSCQ-------RRAGTKRSSRSSHRS----QPSSGDEDSDDASSHRLHQKSPSQYSE 838
PS + + A K+ RS +P DS S + ++ PS
Sbjct: 2647 SSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPS 2706
Query: 839 EEEEEDSGSEH-SRSRSRSGRRHSSHRSSRRSYS 871
+++ S SE SR R R SH+ R + S
Sbjct: 2707 PRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPS 2740
Score = 33.5 bits (75), Expect = 1.6
Identities = 55/258 (21%), Positives = 97/258 (37%), Gaps = 36/258 (13%)
Query: 459 SEVSEQPKETSMTEPS-----EPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSS 513
S+V E P T +PS +P + + + S S S S S + S+ S
Sbjct: 2504 SDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDS 2563
Query: 514 KETSL-------------ATPAGKES-QEG-PKHPTGPFFPVLSKDESTALQWPSELLIF 558
+ +SL TPA KE+ +EG P PT P K S++ S
Sbjct: 2564 EGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPT----PAKRKRRSSSSSSSSSSSSS 2619
Query: 559 TKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVG 618
+ + S S S + S + + + + S +K Q L P + K
Sbjct: 2620 SSSSSSSSSSSS--------SSSSSSSSSSSSSSSSSPSPAKPGPQAL-PKPASPKKPPP 2670
Query: 619 GEKIVRSSGGRMDA--PASGSACSGLNKQEPGGSHGSETEDTGRS-LPSKKERSGKSHRH 675
GE+ RS +D+ + + S + ++ P + + S S++ + G S
Sbjct: 2671 GERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSP 2730
Query: 676 KKKKKHKKSSKHKRKHKA 693
K++ + S +H++
Sbjct: 2731 SHKRRRETPSPRPMRHRS 2748
Score = 33.5 bits (75), Expect = 1.6
Identities = 37/152 (24%), Positives = 57/152 (37%), Gaps = 15/152 (9%)
Query: 417 SEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEP 476
S D + ++ P PE P P K A +G +P E + +
Sbjct: 2558 SSSSDSEGSSLPVQ-PEVALKRVPSPTPAPKEAVREG----------RPPEPTPAKRKRR 2606
Query: 477 GSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTGP 536
S + + + S S S S S + S+SS +S +PA Q PK P P
Sbjct: 2607 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK-PASP 2665
Query: 537 FFPVLSKDESTALQWPSELLIFTKAEPSISYS 568
P + S + + P + L + S+SYS
Sbjct: 2666 KKPPPGERRSRSPRKPIDSL---RDSRSLSYS 2694
Score = 32.3 bits (72), Expect = 3.5
Identities = 47/221 (21%), Positives = 73/221 (33%), Gaps = 21/221 (9%)
Query: 961 RSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHS 1020
RSSS S S S S S+++ S S S S + P Q + KR +P + +
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRV-PSPTPAPKEA 2589
Query: 1021 GRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDC 1080
R R P + R S ++ S +S+ + S
Sbjct: 2590 VREG-------RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
Query: 1081 SPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLG 1140
S + AK + + +KP E +P K L+D SL
Sbjct: 2643 SSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRD----------SRSLS 2692
Query: 1141 NKPVLPLIGKLPATRKPNKKCEESGLERGEEQEQSETEEGP 1181
PV + P+ + + + S ERG + Q P
Sbjct: 2693 YSPV---ERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSP 2730
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 109 bits (272), Expect = 2e-23
Identities = 142/630 (22%), Positives = 244/630 (38%), Gaps = 97/630 (15%)
Query: 553 SELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPN 612
S+ I TK P + + + F +S + R +K D S ++ L GE
Sbjct: 122 SQFFITTKPTPHLDG--HHVVFGQVISGQEVVREIENQKT-DAASKPFAEVRILSCGELI 178
Query: 613 KSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKS 672
+V E+ R + +S + S + Q S SE+ +S KK+ S
Sbjct: 179 PKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNS 238
Query: 673 HRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEK----------------------SKK 710
+HKK+KK +K SK +++ E ++ +S + K+
Sbjct: 239 RKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKE 298
Query: 711 RKKRKRKKNKSSAPADSE-------------------RGPKPEPPGS---------GSPA 742
RK R+R++ + P +S+ RGP+ S S
Sbjct: 299 RKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSET 358
Query: 743 PPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPP----SSCQRR 798
PP R+ Q + R E G K E +Q R + ++ S R
Sbjct: 359 PPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNR 418
Query: 799 AGTKRSSRSSHRSQPSSGD----EDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRS 854
K H+S D + DD +++ +++ S+ + +E+ E +
Sbjct: 419 KNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHN 478
Query: 855 RSGRRHSSHRSSRRSYSS--SSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSD 912
R+ + RS R + + + SD ++RS S + +S H
Sbjct: 479 RNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEH-------- 530
Query: 913 DSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKR 972
D++ SK + +R + S + D ++ + S TRERSRSR RSR SR+ +
Sbjct: 531 --DHSKSKEKDRRAQSRSRECD----ITKGKHSYNSRTRERSRSRDRSRRVR-SRTHDRD 583
Query: 973 RSRSTTAHSW--QRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKI 1030
RSRS H + Q R R RSR R+P RS S+ +R RRD S+
Sbjct: 584 RSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSK----------DRRRRRRDSRSSER 633
Query: 1031 YRSQSPH--YFRSGRGEGPGKKDDGRGDDSKATGPPSQN-SNIGTGRGSEGDCSPEDK-- 1085
SQS + +R+ + +K++ + + N SN + ++ D SP K
Sbjct: 634 EESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIK 693
Query: 1086 -NSVTAKLLLEKIQSRKVER-KPSVSEEVQ 1113
+S +L +++++ E+ + SV +E Q
Sbjct: 694 QSSQDNELKSSMLKNKEDEKIRSSVEKENQ 723
Score = 77.0 bits (188), Expect = 1e-13
Identities = 96/411 (23%), Positives = 166/411 (40%), Gaps = 74/411 (18%)
Query: 653 SETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKR--KHKADTEEKSSKAESGEKSKK 710
+E ++ RS KER HR+ + ++K+ K K+ HK++++E+ + S EK K
Sbjct: 389 NEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNS-EKDDK 447
Query: 711 RKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKD 770
K + +K+ KS + + S+ K + S +R R++
Sbjct: 448 YKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSR------------------- 488
Query: 771 EGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRS-QPSSGDEDSDDASSHRLH 829
S +DH K K + S + + SRS +S Q S + D + S
Sbjct: 489 -----SKGRDHENVKEKEKQSDS----KGKDQERSRSKEKSKQLESKSNEHDHSKSKEKD 539
Query: 830 QKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSY 889
+++ S+ E + + S +SR+R RS S RS R R R++
Sbjct: 540 RRAQSRSRECDITKGKHSYNSRTRERS---RSRDRSRR----------------VRSRTH 580
Query: 890 SDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSH 949
DR R SK H + +Y R + + RSRS+
Sbjct: 581 ---------DRDRSRSKEYHRYREQEYRRRGRSRSRERRT----------PPGRSRSKDR 621
Query: 950 TRERSRSRGRSRSSSCSRSRSK-RRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKR 1008
R R SR R S SR++ K R S ++H + S S R S+S S + K+
Sbjct: 622 RRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKK 681
Query: 1009 SWGHESP--EERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDD 1057
+ +SP + + S + + ++S + +++ RS E +K G+ +D
Sbjct: 682 ADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSS-VEKENQKSKGQEND 731
Score = 35.0 bits (79), Expect = 0.55
Identities = 55/290 (18%), Positives = 104/290 (35%), Gaps = 33/290 (11%)
Query: 447 KAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQ 506
K A S+ K+ + + +++ E ++ +K +V ++ +S S+ +
Sbjct: 454 KRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQ-- 511
Query: 507 MCESNSSKETSLATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSIS 566
E + SKE S + + K SK++ Q S TK +
Sbjct: 512 --ERSRSKEKSKQLESKSNEHDHSK----------SKEKDRRAQSRSRECDITKGK---- 555
Query: 567 YSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHL--------QGLDPGE-----PNK 613
+S N + SR++ R + +D S + H +G P +
Sbjct: 556 HSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGR 615
Query: 614 SKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSH 673
S+ + R S + QE SH E ++ + + SK S+
Sbjct: 616 SRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSN 675
Query: 674 RHKKKKKHKKSSKHK--RKHKADTEEKSSKAESGEKSKKRKKRKRKKNKS 721
++KK + S ++ D E KSS ++ E K R +++ KS
Sbjct: 676 NSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKS 725
Score = 33.5 bits (75), Expect = 1.6
Identities = 29/133 (21%), Positives = 54/133 (40%), Gaps = 12/133 (9%)
Query: 1058 SKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPN 1117
S ++ S + + + S+ + + E+K+ K + + K E+K + A+
Sbjct: 199 SSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSE 258
Query: 1118 KAGPKLKDPPQGYFGP-KLPPSLGNKPVLPLIGKLPATRKPNKKCEESGLERGEEQEQSE 1176
L+ PQ P ++PP N+ ++ RK K +E ER + + E
Sbjct: 259 SEAENLEAQPQSTVRPEEIPPIPENRFLM---------RKSPPKADEK--ERKNRERERE 307
Query: 1177 TEEGPPGSSDALF 1189
E PP S A +
Sbjct: 308 RECNPPNSQPASY 320
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 107 bits (267), Expect = 9e-23
Identities = 96/341 (28%), Positives = 156/341 (45%), Gaps = 28/341 (8%)
Query: 655 TEDTGRSLPSKKERSGKSHR--HKKKKKHKKS---SKHKRKHKADT-EEKSSKAESGEKS 708
TE GR + +++ G R + + + H +S S+H RK ++ + KSS ++S +S
Sbjct: 163 TEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRS 222
Query: 709 K-----KRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEE 763
+ + K R R +++S + + R P E S S + + R +++D ++ +
Sbjct: 223 RSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKI----- 277
Query: 764 GSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGT-KRSSRSSHRSQPSSGDED--- 819
+ ++ G S+ K K + S +RR KR S S RSQ S +
Sbjct: 278 ----QNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSR 333
Query: 820 --SDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDAS 877
S S R +S S+ + + SRSRSRS S R S+R + S
Sbjct: 334 SRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKK 393
Query: 878 SDQSCYSRQRSYSDD-SYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYS 936
+ R +S S S S + ++ S + +S+ A + ++ S+S +
Sbjct: 394 KKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPN 453
Query: 937 L-SCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRS 976
L S S+SRS+S S TR RS+SR RS S S SRSRS+ SRS
Sbjct: 454 LPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 100 bits (249), Expect = 1e-20
Identities = 104/351 (29%), Positives = 142/351 (40%), Gaps = 59/351 (16%)
Query: 624 RSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLP-----SKKERSGKSHRHKKK 678
RS R SGS+ S +K GS + RS SKKE+S + K +
Sbjct: 197 RSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSR 256
Query: 679 KKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGS 738
+ + K + K K EEK ++ K K R + K S ER + E GS
Sbjct: 257 SRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGS 316
Query: 739 GSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRR 798
S R R+Q+ S R+S S S+ GG + + S +R
Sbjct: 317 VS------RGRSQEKSLRQS----------------RSRSRSKGGSRSRSRSRSKSKDKR 354
Query: 799 AGTKRSSRSSH-RSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSG 857
G KRS S RS+ S E S S R S + S+++++ED+ SRS SRS
Sbjct: 355 KGRKRSREESRSRSRSRSKSERSRKRGSKR---DSKAGSSKKKKKEDTDRSQSRSPSRSV 411
Query: 858 RRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYA 917
+ H S S S + RS RSR +SK S + +
Sbjct: 412 SKEREHAKSESSQREGRGESENAGTNQETRS-----------RSRSNSK----SKPNLPS 456
Query: 918 SSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRS 968
S+ RSK S S++RSRS+S +R SRS RSRS S SRS
Sbjct: 457 ESRSRSK-------------SASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 96.3 bits (238), Expect = 2e-19
Identities = 86/290 (29%), Positives = 124/290 (42%), Gaps = 18/290 (6%)
Query: 743 PPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTK 802
P RRRR+ S+ S +K GSS H + + S + R+ ++
Sbjct: 177 PGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSR---SGSRSRSKSR 233
Query: 803 RSSRSSHRSQPSSGDEDSDDASSHRLHQ--KSPSQYSEEEEEEDSGSEH-SRSRSRSGRR 859
S+S RS+ S + S R H KS S+ ++ EE+ +++ + +SRS R
Sbjct: 234 SRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR 293
Query: 860 HSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASS 919
H S SR + SR RS S RSR SK S + S
Sbjct: 294 HKSKSKSRSRSQERRVEEEKRGSVSRGRS---QEKSLRQSRSRSRSKGGSRSRSRSRSKS 350
Query: 920 KHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTA 979
K + K K S + S+SRSRSRS + ERSR RG R S S+ K++ + +
Sbjct: 351 KDKRKGRKRSREE-------SRSRSRSRSKS-ERSRKRGSKRDSKAGSSKKKKKEDTDRS 402
Query: 980 HSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSK 1029
S SRS S++R + SQR G R S + +E S R +SK
Sbjct: 403 QSRSPSRSVSKEREHAKSESSQREG-RGESENAGTNQETRSRSRSNSKSK 451
Score = 91.3 bits (225), Expect = 6e-18
Identities = 117/387 (30%), Positives = 165/387 (42%), Gaps = 74/387 (19%)
Query: 771 EGGGGSSSQDHGGRKHKG--ELPPSSCQRRA-----GTKRSSRSSHRSQPSSGDEDSDDA 823
+ G + + H GRK++G E S +RA GT+ + R + G
Sbjct: 126 QAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSY 185
Query: 824 SSHRLHQKSPSQYSEEEEEEDSGSEHSR-SRSRSGRRHSSHRSSR-RSYSSSSDASSDQS 881
S R H +S S+ S HSR SRSRSG SSH SR RS S S S +S
Sbjct: 186 SRSRSHSRSRSR-----------SRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS 234
Query: 882 -CYSRQRSYSDDSYSDYSD--RSRRHSKRSHDSDDSDYAS-----------------SKH 921
SR RS + S S + RSR HS S D A S+H
Sbjct: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294
Query: 922 RSKRHKYSSS-----DDDYSLSCSQSRS--------RSRSHTRERSRSRGRSRSSSCSRS 968
+SK S S +++ S S+ RS RSRS ++ SRSR RSRS S +
Sbjct: 295 KSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKR 354
Query: 969 RSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRS 1028
+ ++RSR + SRS SR RS+S R S++ GS++ S S +++ + D RS
Sbjct: 355 KGRKRSR-------EESRSRSRSRSKSER--SRKRGSKRDSKAGSSKKKK---KEDTDRS 402
Query: 1029 KIYRSQSPHYFRSGRGE---GPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDK 1085
+S+SP S E + +GRG+ A S + S+ + E +
Sbjct: 403 ---QSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESR 459
Query: 1086 N---SVTAKLLLEKIQSRKVERKPSVS 1109
+ S + K +SR R PS S
Sbjct: 460 SRSKSASKTRSRSKSRSRSASRSPSRS 486
Score = 68.2 bits (165), Expect = 6e-11
Identities = 68/263 (25%), Positives = 107/263 (40%), Gaps = 26/263 (9%)
Query: 579 SRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKI----------VRSSGG 628
SR+K +++ K K S S+ H G +KSK+ EKI RS
Sbjct: 240 SRSKKEKSRSPSKEK---SRSRSHSAGKSR---SKSKDQAEEKIQNNDNVGKPKSRSPSR 293
Query: 629 RMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHK 688
S S +E S +SL + RS + + + + SK K
Sbjct: 294 HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDK 353
Query: 689 RKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPR--- 745
RK + + E+ S++ S +SK + RKR + S S++ K + S S +P R
Sbjct: 354 RKGRKRSREE-SRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVS 412
Query: 746 -RRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQR-RAGTKR 803
R A+ +S +R E ++G E + S+ K K LP S R ++ +K
Sbjct: 413 KEREHAKSESSQREGRGESENAGTNQE----TRSRSRSNSKSKPNLPSESRSRSKSASKT 468
Query: 804 SSRSSHRSQPSSGDEDSDDASSH 826
SRS RS+ +S + SH
Sbjct: 469 RSRSKSRSRSASRSPSRSRSRSH 491
>gi|50083281 KIAA1853 protein [Homo sapiens]
Length = 611
Score = 103 bits (257), Expect = 1e-21
Identities = 147/535 (27%), Positives = 201/535 (37%), Gaps = 135/535 (25%)
Query: 579 SRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSA 638
SR K + K T K + SS P K K+ +K R
Sbjct: 106 SRGKKKKKKSTRKKRRRSSS-------YSPSPVKKKKKKSSKKHKRRRS----------- 147
Query: 639 CSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKS-SKHKRKHKADTEE 697
++ S S+ D R + R KSHRH+ + +S S R ++
Sbjct: 148 -FSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRH 206
Query: 698 KSSKAESGEKSKKRKKRKRKKN--KSSAPADSERGPKPEP-------------PGSGSPA 742
+ E G+KS++R R+ K K S A S R P +P GSGS A
Sbjct: 207 RGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPS-QPLQMLGYLSARGVITGSGSAA 265
Query: 743 P---------PRRRRRAQD--------------DSQRRSLPAEEGS------------SG 767
R R+Q+ S RS E+GS SG
Sbjct: 266 DLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSG 325
Query: 768 KKDEGGGG---SSSQDHG-----------GRKHKGELPPSSCQRRAGTKRSSR--SSHRS 811
+ G SS Q+ G GR+ +G P C A K+SS S+ RS
Sbjct: 326 NTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSP--CLECAEVKKSSLVPSTARS 383
Query: 812 QPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYS 871
P G S +S R S +S + +++SRS S + S RS SYS
Sbjct: 384 SPMKGCSRSSSYASTR-----SSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSP--SYS 436
Query: 872 SSSDASSDQSCYSR-QRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRS-----KR 925
S S S S SR +RS S YS +R ++S++ + + A + RS KR
Sbjct: 437 SKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKR 496
Query: 926 HK-------------------------------YSSSDDDYSLSCSQSRSRSRSHTRERS 954
+ SS+ YS S S+S SRS S +R RS
Sbjct: 497 RRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRS 556
Query: 955 RSRGRS--RSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRK 1007
RSR RS R+SS S SRS + + S RSRS SR +SRS S S +R+
Sbjct: 557 RSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTRR 611
Score = 77.4 bits (189), Expect = 1e-13
Identities = 112/442 (25%), Positives = 170/442 (38%), Gaps = 50/442 (11%)
Query: 646 EPGGSHGSETEDTGRSLPSKKERSGK----------SHRHKKKKKHKKSSKHKRKHKADT 695
EP G++ E + T R L + + S S KKKKK + + + + +
Sbjct: 70 EPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPS 129
Query: 696 EEKSSKAESGEKSKKRKK-RKRKKNKSSAPADSERGPKPEPPGSGS-PAPPRRRRRAQDD 753
K K +S +K K+R+ K++++ SS+P R K S S P R R +
Sbjct: 130 PVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCP 189
Query: 754 SQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQP 813
S+ +S + S + G Q R+H + C+ + + S SQP
Sbjct: 190 SRSQSSESRPSSCESRHRGRSPEEGQ-KSRRRHSRRCSKTLCK---DSPEAQSSRPPSQP 245
Query: 814 -------SSGDEDSDDASSHRLHQKSPSQYSE---EEEEEDSGSEHS----------RSR 853
S+ + S+ L K+ S + +E DSG++ S RSR
Sbjct: 246 LQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSR 305
Query: 854 SRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDS-- 911
+ S S R +S + + S S + + S SR R S
Sbjct: 306 GQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPC 365
Query: 912 ------DDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSC 965
S S RS K S Y+ + S S S SRS S +SRS+S
Sbjct: 366 LECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHS-SRSPNPRASPRYTQSRSTS- 423
Query: 966 SRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDF 1025
S RS RS S ++ S +RS RSR + S S+ S SR+R + + + R
Sbjct: 424 SEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERA 483
Query: 1026 IRSKIYRSQSPHYFRSGRGEGP 1047
R + RS SP R R + P
Sbjct: 484 RRRR--RSYSP--MRKRRRDSP 501
Score = 40.0 bits (92), Expect = 0.017
Identities = 49/195 (25%), Positives = 80/195 (41%), Gaps = 35/195 (17%)
Query: 923 SKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSR-SKRRSRSTTAHS 981
++ H S D S+ + + + TR++ R RSSS S S K++ +S+ H
Sbjct: 89 TRGHSASHDKDLTPPPSSRGKKKKKKSTRKK-----RRRSSSYSPSPVKKKKKKSSKKH- 142
Query: 982 WQRSRSYSRDRSRSTRSP--SQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQS-PHY 1038
+R RS+S+ R S+ SP +R R + P + H R S+ S+S P
Sbjct: 143 -KRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSS 201
Query: 1039 FRS---GRGEGPGKKDDGR------------GDDSKATGPPSQ---------NSNIGTGR 1074
S GR G+K R +++++ PPSQ + TG
Sbjct: 202 CESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGS 261
Query: 1075 GSEGDCSPEDKNSVT 1089
GS D + + +T
Sbjct: 262 GSAADLFTKTASPLT 276
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 100 bits (248), Expect = 1e-20
Identities = 158/722 (21%), Positives = 254/722 (35%), Gaps = 95/722 (13%)
Query: 429 KNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKKALGG 488
K+A ++ KP + + S + K+ S K PS S+ +K
Sbjct: 36 KSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTST--KRAPSNRPSSR-SRVRSKARTPS 92
Query: 489 DVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTGPFFPVLSKDESTA 548
VS + S + K S+ + C + TP + S+ + P+ P +
Sbjct: 93 RVSTDTRTSKASKASDVR-CHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGAR 151
Query: 549 LQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDP 608
S + T S+ K +R K +P+ +S+++
Sbjct: 152 PGMASRVRTPT-------------------SQQKGSRGKSYGRPR---TSNRERSDSQPR 189
Query: 609 GEPNKS-KEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKE 667
KS + GG I RSS + S + C Q P G E D S+K
Sbjct: 190 NLSKKSYRPPGGSGIGRSS--ELAVTPSTAKC-----QTPTGIPSKEKSDNPSPSSSRKV 242
Query: 668 RSGKS----HRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSA 723
+S R K + SS+ K ++A T + ++ + +K+ S
Sbjct: 243 KSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRV 302
Query: 724 PADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHG- 782
+ S + R RA+ +++ L S + G S +Q
Sbjct: 303 RSHSWK---------------RNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTP 347
Query: 783 --GRKHKGELPPS-----SCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQ 835
GR H PS S R + +R R S + SG S + R H +S S
Sbjct: 348 RRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSP 407
Query: 836 YSEEEEEEDSGSEHSRSRSRS---------GRRHSSHRSSRRSYSSSSDASSDQSCYSRQ 886
+ +R RSRS R S +++ RS S S + + D S
Sbjct: 408 NKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSP 467
Query: 887 RSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRH-----KYSSSDDDYSLSCSQ 941
D S S + R HS+ S + D+ S+ SK + SS + D+ S S
Sbjct: 468 NKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSP 527
Query: 942 SRSRSRSHTRE--RSRSRGRSRSSSCSRS--RSKRRSRSTTAHSWQRSRSYSRDRSRSTR 997
S+ R R +R + R R +SRS S R +S+ S+ W RS S R+R +S
Sbjct: 528 SKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRW-RSPSKERERRQSRS 586
Query: 998 SPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDD 1057
S +R SR RS +S + R + + H R P K +G
Sbjct: 587 SSEERDHSRSRSPNKQS---------GYSRPRASSKEKAH----SRSRTPSK--EGNHSQ 631
Query: 1058 SKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPN 1117
S+ + S S R + SP +S++ K S PS + + +
Sbjct: 632 SRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDS 691
Query: 1118 KA 1119
+A
Sbjct: 692 QA 693
Score = 94.7 bits (234), Expect = 6e-19
Identities = 175/730 (23%), Positives = 276/730 (37%), Gaps = 117/730 (16%)
Query: 624 RSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSL-PSKKERSGKSHRHKKKKKHK 682
RSS M SGS+ + + P +++ RSL P+K S S K
Sbjct: 6 RSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKST 65
Query: 683 KSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPAD----SERGPKPE---P 735
KS+ KR ++ S+ S ++ R + +K+S +D RG P
Sbjct: 66 KSTSTKRA-PSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTP 124
Query: 736 PGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGK------KDEGGGGSS-SQDHGGRKHKG 788
GS + R RA + R+ A G + + + +G G S + + +
Sbjct: 125 GRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERS 184
Query: 789 ELPPSSCQRR-------AGTKRSSR-----SSHRSQ-----PSSGDEDSDDASSHRLHQK 831
+ P + ++ +G RSS S+ + Q PS D+ SS R +
Sbjct: 185 DSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKS 244
Query: 832 -------------SPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASS 878
SP++ S + + S SR +S HS RS RRS S S
Sbjct: 245 YGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQS-----HSQSRSPRRSRS-----GS 294
Query: 879 DQSCYSRQRSYS-DDSYSDYSDRSR--------RHSK-RSHDSDDSDYAS-SKHRSKRHK 927
+ +SR RS+S ++S R+R RHS+ RSH S S + R + H
Sbjct: 295 QKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHN 354
Query: 928 YS---SSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRS-TTAHSWQ 983
+S S + +S S S S+ R + + GRS+S S ++ R RSRS A
Sbjct: 355 WSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRS 414
Query: 984 RSRS--YSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRS 1041
RSRS +RDRSRS R SR RS +R R RS+SP+ R
Sbjct: 415 RSRSPYKARDRSRSRSPNKARDCSRSRS--PYKARDRSRSRSPNKARDHSRSRSPNKARD 472
Query: 1042 -GRGEGPGKKDD-------GRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLL 1093
R P K+ D + D + + PS+ R S + S + +
Sbjct: 473 RSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQ 532
Query: 1094 LEKIQSRKVER----KPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLGNKPVLPLIG 1149
+ +S ER S SEE + +++ K +D +
Sbjct: 533 RRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRR--------------------W 572
Query: 1150 KLPATRKPNKKCEESGLERGEEQEQSETEE---GPPGSSDALFGH---QFPSEETTGPLL 1203
+ P+ + ++ S ER + +S ++ P +S H + PS+E
Sbjct: 573 RSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQS 632
Query: 1204 DPPPEESKSGEATA----DHPVAPLGTPAHSDCYPGDPTISHNYLPDPSDGDTLESLDSS 1259
+ES ++T D +P T + S T SH+ PS G TL DS
Sbjct: 633 RTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQ 692
Query: 1260 SQPGPVESSL 1269
+ +++L
Sbjct: 693 ADATTSKATL 702
Score = 35.8 bits (81), Expect = 0.32
Identities = 41/196 (20%), Positives = 76/196 (38%), Gaps = 20/196 (10%)
Query: 579 SRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSA 638
S +K+ + + + P + +D Q P E + ++ RS D S
Sbjct: 526 SPSKERQRRQSRSP----NKERDRSQSRSPSEEREHRQS------RSPSKERDRRRWRSP 575
Query: 639 CSGLNKQEPGGSHGSETEDTGRSL-PSKKERSGKSHRHKKKKKHKKS-SKHKRKHKADTE 696
+++ S SE D RS P+K+ + K+K H +S + K + + +
Sbjct: 576 SKERERRQSRSS--SEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSR 633
Query: 697 EKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQ- 755
S +++ + + R ++ ++ R P S S P + +QDDSQ
Sbjct: 634 TSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQA 693
Query: 756 -----RRSLPAEEGSS 766
+ +LP E SS
Sbjct: 694 DATTSKATLPGERSSS 709
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 99.4 bits (246), Expect = 2e-20
Identities = 175/758 (23%), Positives = 270/758 (35%), Gaps = 128/758 (16%)
Query: 417 SEQMDGD-NTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSE 475
SE+ G + H +A E + S P+S + A G S S + T T+ S
Sbjct: 2580 SERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGH----SADSSRQSGTRHTQTSS 2635
Query: 476 PGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTG 535
G A + + ++ H Q ++ + +S +G G +
Sbjct: 2636 GGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDN 2695
Query: 536 PFFPVLSKDESTALQWPSELLIFTKAEP----SISYSCNPLYFDFKLSRNKDARTK-GTE 590
S +S + + + E S S + F +++S ++ + + G
Sbjct: 2696 EGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWT 2755
Query: 591 KPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVR-----SSGGRMDAPASGSACSGLNKQ 645
P G H Q D + S++ G+ +R S GGR S S +
Sbjct: 2756 GPSTRGRQGSRHEQAQDSSRHSASQD--GQDTIRGHPGSSRGGRQGYHHEHSVDSSGHS- 2812
Query: 646 EPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKS--SKHK--RKHKADTE---EK 698
GSH S T GRS S+ + +S + + + S+H R H+A T +
Sbjct: 2813 ---GSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISR 2869
Query: 699 SSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAP-------------PR 745
S+A G+ R+ R R+ + S +DSE + SGS + R
Sbjct: 2870 HSQAVQGQSEGSRRSR-RQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSR 2928
Query: 746 RRRRAQDDSQRRSLPAEE----GSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGT 801
R Q+D A+ G+ + GG ++S R GE S Q+ A +
Sbjct: 2929 HPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADS 2988
Query: 802 KRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEE-EEEDSGSEHSRSRSRSGRRH 860
R S H Q SS DS HR + S SQ S+ E EDS ++ + ++G
Sbjct: 2989 SRHSGIGH-GQASSAVRDS----GHRGY--SGSQASDNEGHSEDSDTQSVSAHGQAGSHQ 3041
Query: 861 SSHRSSRRSYSSSSDASSDQSCY---SRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYA 917
SH+ S R S + S Y + ++S S ++ S R R+ S+ D S ++
Sbjct: 3042 QSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHS 3101
Query: 918 SSK------------------------------HRSKRHKYSSSDDDYSLSCSQSRSRSR 947
+S+ H H +++S S QS SRS
Sbjct: 3102 ASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSA 3161
Query: 948 SHTRERSRSRGRSRSSSCSR--------------------SRSKRRSRSTTAHSWQRSRS 987
S T G S S SR S RRSR + Q S S
Sbjct: 3162 SRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDS 3221
Query: 988 --YSRDRSRSTRSPSQ----------RSGSR--------KRSWGHESPEERHSGRRDFIR 1027
+S D R + S S+ R GSR + GH + R SG R
Sbjct: 3222 EGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAET 3281
Query: 1028 SKIYRSQSPH-YFRSGRGEGPGKKDDGRGDDSKATGPP 1064
S ++ S H RS GE G + D S+ +G P
Sbjct: 3282 SSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIP 3319
Score = 98.6 bits (244), Expect = 4e-20
Identities = 167/739 (22%), Positives = 262/739 (35%), Gaps = 95/739 (12%)
Query: 417 SEQMDGD-NTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSE 475
SE+ G + H +A E + S P+S + A G S S P + +
Sbjct: 959 SERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQA 1018
Query: 476 PGSKAEAKKALG---GDVSDQSLESHSQKVSETQMCES---------NSSKETSLATPAG 523
S +A+ + G G QS +S + S +S + S +
Sbjct: 1019 ASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHS 1078
Query: 524 KESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKD 583
+ES G P + +A W S S F +++S ++
Sbjct: 1079 EESDTQSVSGHGQDGPHQQSHQESARDW------------SGGRSGRSGSFIYQVSTHEQ 1126
Query: 584 ARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLN 643
+ + G H + + + + G + I G R ++
Sbjct: 1127 SESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVD 1186
Query: 644 KQEPGGSHGSETEDTGRSLPSKKERSGKS--HRHKKKKKHKKSSKHK--RKHKADTEEKS 699
+ GSH S T GRS S + +S + +K K+ S+H R H+A + S
Sbjct: 1187 RSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADS 1246
Query: 700 SK-AESGEKSKKRKKRKRKKNKS-SAPADSERGPKPEPPGSGSPAPPRR---RRRAQDDS 754
S+ ++ G++ + R + S S +DSER SGS + R +++D S
Sbjct: 1247 SRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGS 1306
Query: 755 QRRSLPAEEGSS------GKKDEGGGGSSSQDHG--------GRKHKGELPPSSCQRRAG 800
+ E+ +S + G + S HG R GE S Q+ A
Sbjct: 1307 RHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSAD 1366
Query: 801 TKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEE-EEEDSGSEHSRSRSRSGRR 859
+ R S HR Q SS DS S S SQ + E EDS ++ + ++G
Sbjct: 1367 SSRHSGIGHR-QASSAVRDSGHRGS------SGSQVTNSEGHSEDSDTQSVSAHGQAGPH 1419
Query: 860 HSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASS 919
SH+ S R S S S Y Q S + S S + + R + SS
Sbjct: 1420 QQSHKESARGQSGESSGRSRSFLY--QVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSS 1477
Query: 920 KHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTA 979
+H + S D ++ SR +S RS S S + + RS +
Sbjct: 1478 RHSA------SQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDAS 1531
Query: 980 HSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYF 1039
H +S R SR TR+ Q RHSG R S R+ S +
Sbjct: 1532 HG----QSGPRSASRQTRNEEQSGDG-----------SRHSGSRHHEPST--RAGSSRHS 1574
Query: 1040 RSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAK---LLLEK 1096
+ G+GE G K R Q S++ R SEG ++ S +A +
Sbjct: 1575 QVGQGESAGSKTSRR-----------QGSSVSQDRDSEGHSEDSERRSESASRNHYGSAR 1623
Query: 1097 IQSRKVERKPSVSEEVQAT 1115
QSR R P +E +A+
Sbjct: 1624 EQSRHGSRNPRSHQEDRAS 1642
Score = 95.1 bits (235), Expect = 4e-19
Identities = 230/1054 (21%), Positives = 351/1054 (33%), Gaps = 163/1054 (15%)
Query: 452 QGAEKTVSEVSEQPKETSMTEP-SEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCES 510
Q + + S++ ++T P S G + + D S S HS S+ + S
Sbjct: 1148 QARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDAS 1207
Query: 511 NS---SKETSLATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISY 567
+ S+ S T K+S +G +H A W + S
Sbjct: 1208 HGQSGSRSASRQTRKDKQSGDGSRHS--------GSRHHEAASWADSSRHSQVGQEQSSG 1259
Query: 568 SCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSG 627
S + +S++ D+ + + GS+S++H + S+ G + R+S
Sbjct: 1260 SRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASH 1319
Query: 628 GRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKH 687
G A S SG + E SHG ++ S ER G H+ H
Sbjct: 1320 GHS---ADSSRQSGTHHTE-SSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGH 1375
Query: 688 KRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGP-----KPEPPGSGSPA 742
++ A + + SG + + + S A + GP K G +
Sbjct: 1376 RQASSA-VRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGES 1434
Query: 743 PPRRR--------RRAQDDSQRRSLPAEEGSSGKKDEGGGGSS--SQDHGGRKHKGELPP 792
R R + + ++ P+ G G + E SS S G+ P
Sbjct: 1435 SGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPG 1494
Query: 793 SSCQRRAGTKRSS---RSSHRSQPSSGD--EDSDDASSHRLHQKSPSQYSEEEEEEDSGS 847
SS R G+ RS H S + DAS + +S S+ + EE+ GS
Sbjct: 1495 SSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGS 1554
Query: 848 EHSRSR-----SRSGR-RHS---------SHRSSRRSYSSSSDASSD---QSCYSRQRSY 889
HS SR +R+G RHS S S R+ S S D S+ + R S
Sbjct: 1555 RHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESA 1614
Query: 890 SDDSYSDYSDRSRRHSK--RSHDSDDSDYA----SSKHRSKRHKYSSSDDDYSLSCSQSR 943
S + Y ++SR S+ RSH D + + SS+ RH +SS + SQ +
Sbjct: 1615 SRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGG--QAASSQEQ 1672
Query: 944 SRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRS---------------- 987
+RS R SR + +S SS +R+ S S R S
Sbjct: 1673 ARSSPGERHGSRHQ-QSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDT 1731
Query: 988 -----------YSRDRSRSTRSPSQRSGSRKRSW-----GHESPEERH------SGRRDF 1025
+ + STR S R S+ HE E H +G R
Sbjct: 1732 QSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQR 1791
Query: 1026 IRSKIYRSQSPH------------YFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTG 1073
R + R S H + S RG G + D S +G S +S+ +
Sbjct: 1792 SRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSG--SHHSHTTSQ 1849
Query: 1074 RGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKDPPQGY-FG 1132
S+ SV+ + EK QS R S S +A+ + QG G
Sbjct: 1850 ERSDVSRGQSGSRSVSRQTRNEK-QSGDGSRH-SGSRHHEASSRADSSRHSQVGQGQSSG 1907
Query: 1133 PKLPPSLGNKPVLPLIGKLPATRKPNKKCEESGLERGEEQEQSETEEGPPGS---SDALF 1189
P+ + G+ + + S G EQS PGS A
Sbjct: 1908 PRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGH 1967
Query: 1190 GHQFPSEETTGPLLDPPPEESKSGEATADHPVAPLGTPAHSDCYPGDPTISHNYLPDPSD 1249
GH S +G E S G+A + H A G+ SH+
Sbjct: 1968 GHSADSSRQSG---TRHTESSSRGQAASSHEQARSSA--------GERHGSHH------- 2009
Query: 1250 GDTLESLDSSSQPGPVESSLLPIAPDLEHFPSYAPPSGDPSIESTDGAEDASLAPLESQP 1309
L+S DSS G D H SG + +S +ED+ + +Q
Sbjct: 2010 --QLQSADSSRHSGIGHGQASSAVRDSGH----RGYSGSQASDSEGHSEDSDTQSVSAQG 2063
Query: 1310 ITFTPEEMEKYSKLQQAAQQHIQQQLLAKQVKAFPASAAL----APATPALQPIHIQQPA 1365
++ K S Q+ + + QV S + AP+T Q H Q
Sbjct: 2064 KAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQ 2123
Query: 1366 TASATSITTVQHAILQHHAAAAAAAIGIHPHPHP 1399
+S H+A+ I HP P
Sbjct: 2124 DSS-------------RHSASQEGQDTIRGHPGP 2144
Score = 94.7 bits (234), Expect = 6e-19
Identities = 177/779 (22%), Positives = 286/779 (36%), Gaps = 94/779 (12%)
Query: 417 SEQMDGDNTTHP--KNAPESKKGSSPKPKSCIKAAA--SQGAEKTVSEVSEQPKETSMTE 472
+E+ GD++ H ++ S + ++ + S+ + + S VS+ +E
Sbjct: 3167 NEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSE 3226
Query: 473 PSEPGSKAEAKKALGGDVSDQSLES--HSQKVSETQMCESNSSKETSLATPAGKESQEGP 530
SE S A + G V +QS H + E + +S A + Q G
Sbjct: 3227 DSERWS-GSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHS---------ADRSRQSGT 3276
Query: 531 KHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDAR---TK 587
+H + A P E + + S + + S +D+R +
Sbjct: 3277 RHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSS 3336
Query: 588 GTEKPKDIGSSSKDHLQGLDP-GEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQE 646
G++ G S + Q + G+ ++ E SGGR + SGS ++ E
Sbjct: 3337 GSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGR--SGRSGSFLYQVSTHE 3394
Query: 647 PGGS-HGSETEDTGRSLPSKKERSGKSHRHKKKKK-------HKKSSKHKRK-----HKA 693
S HG TGR S E++ S RH ++ H SS+ R+
Sbjct: 3395 QSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSV 3454
Query: 694 DTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDD 753
D S S S+ R R ++ S + + R + GS Q D
Sbjct: 3455 DRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQAD 3514
Query: 754 SQRRSLPAEEGSSGKKDEGGGGSS-SQDHGGRKHKGELP----PSSCQRRAGTKRSSRSS 808
S R S + S+G + GSS SQD + H + +S R + SR
Sbjct: 3515 SSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDG 3574
Query: 809 HRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHR---- 864
R S ++ + S ++S + ++E + S H ++RS +G RH SH
Sbjct: 3575 SRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSA 3634
Query: 865 -SSRRS---YSSSSDASSDQSCYSRQRSYSDDS--YSDYSD--------RSRRHSKRSHD 910
SSR S + +S A D S + DS +S+ SD ++ H + +
Sbjct: 3635 DSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQE 3694
Query: 911 SDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSR---SRGRSRSSSCSR 967
S A RS Y S + S S + R+ + R+ SR +R SR S+
Sbjct: 3695 STRGRSAGRSGRSGSFLYQVSTHEQSES-AHGRAGPSTGGRQGSRHEQARDSSRHSASQE 3753
Query: 968 SR--------SKRRSRSTTAHSWQRSR--------SYSRDRSRSTRSPSQRSGSRKRSWG 1011
+ S+R R + H R S++ + RS S Q SGSR S
Sbjct: 3754 GQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQ-SGSRSASRE 3812
Query: 1012 HESPEE-----RHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQ 1066
+ E+ RHSG R S ++ S + +SG+GE G + R S + S+
Sbjct: 3813 TRNEEQSGDGSRHSGSRHHEAST--QADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSE 3870
Query: 1067 NSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKD 1125
+ R SE +S + QSR R P S A+ ++ P D
Sbjct: 3871 AYPEDSERRSESASRNHHGSS--------REQSRDGSRHPGSSHRDTASHVQSSPVQSD 3921
Score = 94.4 bits (233), Expect = 8e-19
Identities = 134/602 (22%), Positives = 211/602 (35%), Gaps = 119/602 (19%)
Query: 586 TKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQ 645
+ G++ G S Q + ++ ++ R G + S +
Sbjct: 417 SSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHE 476
Query: 646 EPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKK--------------------HKKS- 684
+P +HG TG S E++ S RH ++ H++S
Sbjct: 477 QPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSV 536
Query: 685 --SKHKRKHKADTEEK----SSKAESGEKSKKRKKRKRKK------------NKSSAPAD 726
S H H + T + +S +SG +S R+ R ++ +++S+ AD
Sbjct: 537 NRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQAD 596
Query: 727 SERGPKPEPPGSGSPAPPRRRRR-----AQD-DSQRRSLPAEEGSSGKKDEGGGGSSSQD 780
S R + G G + PR R +QD DSQ S +E S G + Q
Sbjct: 597 SSRHSQ---VGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQS 653
Query: 781 HGGRKH--------KGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDA-----SSHR 827
G +H G + R++GT+ + SS SS ++ A S H+
Sbjct: 654 RDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQ 713
Query: 828 LHQKSPSQYS--------------------------EEEEEEDSGSEHSRSRSRSGRRHS 861
L S++S E EDS ++ ++G
Sbjct: 714 LQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQ 773
Query: 862 SHRSSRRSYSSSSDASSDQSCY---SRQRSYSDDSYS---------DYSDRSRRHSKRSH 909
SH+ S R S S Y + ++S S ++ + +++R +S+ S
Sbjct: 774 SHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSA 833
Query: 910 DSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSR---SRGRSRSSSCS 966
D D S R S + S+ S SHT + R SRG+S S S S
Sbjct: 834 SQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSAS 893
Query: 967 R-SRSKRRSRSTTAHSWQRSRSYS--RDRSR-STRSPSQRSGSR------------KRSW 1010
R +R++ +SR + HS R S D SR S Q GSR S
Sbjct: 894 RTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSE 953
Query: 1011 GHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGR-GDDSKATGPPSQNSN 1069
GH ER SG + QS H R R + G D S+ +G P ++
Sbjct: 954 GHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETS 1013
Query: 1070 IG 1071
G
Sbjct: 1014 SG 1015
Score = 94.0 bits (232), Expect = 1e-18
Identities = 109/499 (21%), Positives = 177/499 (35%), Gaps = 41/499 (8%)
Query: 579 SRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSA 638
S+ + ++G + ++++ Q D + S+ E + R G +
Sbjct: 2821 SQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRH--HEASTHADISRHSQAVQGQS 2878
Query: 639 CSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRH--KKKKKHKKSSKHKRKHKADTE 696
+ G S +++ G S S++ S H +++ + S+H R H+ D
Sbjct: 2879 EGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRA 2938
Query: 697 EKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQR 756
A+S +S R + ++++ + R E GS +++ D S+
Sbjct: 2939 GHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGS-------HHQQSADSSRH 2991
Query: 757 RSLPAEEGSSGKKDEGG---GGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQP 813
+ + SS +D G GS + D+ G + S +AG S + SH+
Sbjct: 2992 SGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAG---SHQQSHQESA 3048
Query: 814 SSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSS 873
++ S L+Q S + E+ E G +R R G RH + S R +S
Sbjct: 3049 RGRSGETSGHSGSFLYQVS----THEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSAS- 3103
Query: 874 SDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDD 933
Y D+ + SR + H D SS H H +++S
Sbjct: 3104 --------------QYGQDTIRGHPGSSRGGRQGYHHEHSVD--SSGHSGSHHSHTTSQG 3147
Query: 934 DYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRS 993
S QS SRS S T G S S SR + HS Q + S
Sbjct: 3148 RSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHS-QAVQGQSEGSR 3206
Query: 994 RSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDG 1053
RS R S S S GH ER SG + QS H R R + G
Sbjct: 3207 RSRRQGSSVS-QDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHG 3265
Query: 1054 R-GDDSKATGPPSQNSNIG 1071
D S+ +G ++ G
Sbjct: 3266 HSADRSRQSGTRHAETSSG 3284
Score = 92.8 bits (229), Expect = 2e-18
Identities = 123/500 (24%), Positives = 190/500 (38%), Gaps = 74/500 (14%)
Query: 624 RSSGGRMDAPASGSACSGLNKQEPGGSHGSETE-DTGRSLPSKKERSGKS---------- 672
R SG R +S + SG ++ G S G T + G S + G S
Sbjct: 2528 RHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSA 2587
Query: 673 ---HRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSER 729
H +++ + S+H R H+ D A+S +S R + ++++ + R
Sbjct: 2588 SRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQAR 2647
Query: 730 GPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGG---GGSSSQDHGGRKH 786
E GS +++ D S+ + + SS +D G GS + D+ G
Sbjct: 2648 SSAGERHGS-------HHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSE 2700
Query: 787 KGELPPSSCQRRAGTKRSSRSSH---RSQPSSGDEDS--DDASSHRLHQKS-----PS-- 834
+ S +AG+ + S RS +SG S S+H + S PS
Sbjct: 2701 DSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTR 2760
Query: 835 --QYSEEEEEEDSGSEHSRSR------------SRSGRRHSSHRSSRRSYSSSSDASSDQ 880
Q S E+ +DS S HS S+ SR GR+ H S S S S
Sbjct: 2761 GRQGSRHEQAQDS-SRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHT 2819
Query: 881 SCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYS--LS 938
+ R + S S + R+ R+ ++S D S+H RH +S+ D S
Sbjct: 2820 TSQGRSDASRGQSGSRSASRTTRNEEQSGD-------GSRHSGSRHHEASTHADISRHSQ 2872
Query: 939 CSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRS 998
Q +S +R + S + S S+R S S + + ++ RD SR RS
Sbjct: 2873 AVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRS 2932
Query: 999 PSQ-RSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPH-YFRSGRGEGPGKKDDGRGD 1056
+ R+G GH + R SG R S ++ S H RS GE G D
Sbjct: 2933 HQEDRAGH-----GHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSAD 2987
Query: 1057 DSKATGPPSQNSNIGTGRGS 1076
S+ +S IG G+ S
Sbjct: 2988 SSR-------HSGIGHGQAS 3000
Score = 89.7 bits (221), Expect = 2e-17
Identities = 123/484 (25%), Positives = 183/484 (37%), Gaps = 102/484 (21%)
Query: 649 GSHGSETEDT-GRSLPSKKERSGKSHRHKKK--KKHKKSSKHKRKHKADTEEKSSKAESG 705
GS S+ D+ G S S++ S H ++ + S+H R H D A+S
Sbjct: 294 GSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSS 353
Query: 706 EKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGS 765
+S R + ++++ + R E GSG +++ D S+ + + S
Sbjct: 354 RQSGTRHAETSSRGQTASSHEQARSSPGERHGSG-------HQQSADSSRHSATGRGQAS 406
Query: 766 SGKKDEGGGGSS---SQDHGGRKHKGELPPSSCQRRAGTKRSS-------RSSHRS---- 811
S D G GSS + D G + S +AG ++ S RS RS
Sbjct: 407 SAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSG 466
Query: 812 ----------QPSS-----GDEDSDDASSHRLHQKSPSQYSEEEEEEDS----------- 845
QP S G SH + S++S +E +D+
Sbjct: 467 SSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGG 526
Query: 846 --GSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQS---CYSRQRSYSDDSYSDYSDR 900
GS H +S +RSG HS S + SDAS QS SRQ + S
Sbjct: 527 RQGSHHEQSVNRSG--HSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHS 584
Query: 901 SRRHSKRSHDSDDSDYA------SSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERS 954
RH + S +D S ++ SS R+ R++ SS D S S+ H+ +
Sbjct: 585 GSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQD---------SDSQGHSEDSE 635
Query: 955 RSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQ-RSGSRKRSWGHE 1013
R G S SR+ S ++ SRD SR RS + R+G GH
Sbjct: 636 RWSG-------SASRNHHGS----------AQEQSRDGSRHPRSHHEDRAGH-----GHS 673
Query: 1014 SPEERHSGRRDFIRSKIYRSQSPH-YFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGT 1072
+ R SG R S ++ S H RS GE G + + DS S++S G
Sbjct: 674 ADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADS------SRHSGTGH 727
Query: 1073 GRGS 1076
G+ S
Sbjct: 728 GQAS 731
Score = 89.7 bits (221), Expect = 2e-17
Identities = 161/790 (20%), Positives = 279/790 (35%), Gaps = 114/790 (14%)
Query: 340 DQGLQKVGDSDGSSNLDGKKEDEDPQDGGSLASTLSKLKRMKREEGAGATEPEYYHYIPP 399
+Q + G S + +E D G S + ++S+ R +++ G G+ H+
Sbjct: 1830 EQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEAS 1889
Query: 400 AHCKVKPNFPFLLFMRASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVS 459
+ + Q G T+ + + S+ S + + + +
Sbjct: 1890 SRADSSRHSQV-----GQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLG 1944
Query: 460 EVSEQPKETSMTEPSEPGSKAEAKKALG--GDVSDQSLESHSQKVSETQMCESNSSKETS 517
EQ ++ S PGS E + G D S QS H++ S Q S+ +S
Sbjct: 1945 SAWEQSRDGSR----HPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSS 2000
Query: 518 LATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFK 577
G +H G + S D S + +A ++ S + Y +
Sbjct: 2001 A----------GERH--GSHHQLQSADSSR-----HSGIGHGQASSAVRDSGHRGYSGSQ 2043
Query: 578 LS----RNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAP 633
S ++D+ T+ G + H + G+ +S G + + S
Sbjct: 2044 ASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESAR-GQSGESSGRSGSFLYQVSTHEQSES 2102
Query: 634 ASGSACSGLNKQEPGGSHGSETEDTGRSLPSKK-----------ERSGK--SHRHKKKKK 680
G + ++ GSH + +D+ R S++ R G+ SH+ + +
Sbjct: 2103 THGQSAPSTGGRQ--GSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDR 2160
Query: 681 HKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGS 740
S H + +S+ +SG +S RK ++++ G GS
Sbjct: 2161 SGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQS-----------------GDGS 2203
Query: 741 PAPPRRRRRAQD--DSQRRSLPAEEGSSGKKDEGGGGSS-SQDHGGRKHKGELPPSSCQR 797
A DS R SL + SSG + GSS SQD H +
Sbjct: 2204 RHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSED-------- 2255
Query: 798 RAGTKRSSRSSHRSQPSSGDEDSDDASSH-RLH--------------QKSPSQYSEEEEE 842
++R S S+ R+ S E S D S H R H ++S + ++E
Sbjct: 2256 ---SERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSG 2312
Query: 843 EDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSR 902
+ S H ++RS +G RH SH S S Q+ + + S S + S
Sbjct: 2313 GQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSE 2372
Query: 903 RHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRS-RGRSR 961
HS+ S S + + + H+ S+ S + T E+S S GR+
Sbjct: 2373 GHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTG 2432
Query: 962 SSSCSRSRS-KRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSW--------GH 1012
+S+ R S +++R ++ HS + + P SG R+ S GH
Sbjct: 2433 TSTGGRQGSHHKQARDSSRHS-----TSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGH 2487
Query: 1013 ESPEERHS---GRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDG-RGDDSKATGPPSQNS 1068
H+ GR D + R+ G G + G R ++ + S +S
Sbjct: 2488 SGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHS 2547
Query: 1069 NIGTGRGSEG 1078
+G G+ SEG
Sbjct: 2548 QVGQGQ-SEG 2556
Score = 87.4 bits (215), Expect = 9e-17
Identities = 167/760 (21%), Positives = 245/760 (32%), Gaps = 152/760 (20%)
Query: 423 DNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKAEA 482
D H +A S++ + +S + A+ E+ S E+ + ++ +
Sbjct: 1963 DRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSAD----SSR 2018
Query: 483 KKALG-GDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTGPFFPVL 541
+G G S +S + S +Q +S E S + + GP
Sbjct: 2019 HSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQ-------- 2070
Query: 542 SKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDAR-TKGTEKPKDIGSSSK 600
S ES Q S S F +++S ++ + T G P G
Sbjct: 2071 SHKESARGQ-------------SGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGS 2117
Query: 601 DHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACS-GLNKQEPGGSHGSETEDTG 659
+ Q D + S+E G+ +R G GS +++ GSH S T G
Sbjct: 2118 HYDQAQDSSRHSASQE--GQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQG 2175
Query: 660 RSLPSK--------------KERSGKSHRHKKKKKHKKSS------------------KH 687
RS S+ KE+SG RH H+ SS +
Sbjct: 2176 RSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRT 2235
Query: 688 KRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPK------PEPPGSGSP 741
R + + S E S++R + + SA S G + + G G
Sbjct: 2236 SRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHS 2295
Query: 742 APPRRR---RRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKG--ELPPSSCQ 796
A R+ A++ S ++ + E + E G Q +H G SS
Sbjct: 2296 AESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAV 2355
Query: 797 RRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEE--------------- 841
R +G R S S S EDSD S Q P Q S +E
Sbjct: 2356 RDSG-HRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSF 2414
Query: 842 ------EEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYS 895
E S S H R+ + +G R SH R S S + Q +
Sbjct: 2415 LYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIH--------GHP 2466
Query: 896 DYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSR 955
S R+ S D S ++ S H H S D S S SRS SR +
Sbjct: 2467 GSSSGGRQGSHYEQLVDRSGHSGSHHS---HTTSQGRSDASHGHSGSRSASRQTRNDEQS 2523
Query: 956 SRGRSRSSSCSRSRSKRRSRS-------------TTAHSW-------QRSRSYSRDRSRS 995
G S S S R S T+ +W S+ +S D R
Sbjct: 2524 GDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERW 2583
Query: 996 TRSPSQ----------RSGSR--------KRSWGHESPEERHSGRRDFIRSKIYRSQSPH 1037
+ S S+ R GSR + GH + R SG R S ++ S H
Sbjct: 2584 SGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSH 2643
Query: 1038 -YFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGS 1076
RS GE G D S+ +S IG G+ S
Sbjct: 2644 EQARSSAGERHGSHHQQSADSSR-------HSGIGHGQAS 2676
Score = 86.7 bits (213), Expect = 2e-16
Identities = 163/756 (21%), Positives = 262/756 (34%), Gaps = 137/756 (18%)
Query: 416 ASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSE 475
++++ D + HP++ E + G +S ++ + + + ++ +
Sbjct: 2270 SAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGER 2329
Query: 476 PGS----KAEAKKALG---GDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQE 528
GS A++ + G G S +S + S +Q +S E S Q
Sbjct: 2330 HGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQA 2389
Query: 529 GPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTK- 587
GP S EST + S S F +++S ++ + +
Sbjct: 2390 GPHQQ--------SHQESTRGR-------------SAGRSGRSGSFLYQVSTHEQSESAH 2428
Query: 588 GTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVR-----SSGGRMDAPASGSACSGL 642
G G H Q D + S+E G+ + SSGGR
Sbjct: 2429 GRTGTSTGGRQGSHHKQARDSSRHSTSQE--GQDTIHGHPGSSSGGRQ------------ 2474
Query: 643 NKQEPGGSHGSETED------TGRSLPSKKERSGKSHRHKKKK----------------K 680
GSH + D + S + + RS SH H + +
Sbjct: 2475 ------GSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSR 2528
Query: 681 HKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKR------KRKKNKSSAPADSER----- 729
H S H+ +AD+ S + G+ R R + + DSER
Sbjct: 2529 HSGSRHHEASSRADSSGHSQVGQ-GQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSA 2587
Query: 730 -----GPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGR 784
G E GS P + + G+ + GG ++S R
Sbjct: 2588 SRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQAR 2647
Query: 785 KHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEE-EEE 843
GE S Q+ A + R S H Q SS D S HR + S SQ S+ E E
Sbjct: 2648 SSAGERHGSHHQQSADSSRHSGIGH-GQASSAVRD----SGHRGY--SGSQASDNEGHSE 2700
Query: 844 DSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCY---SRQRSYSDDSYSDYSDR 900
DS ++ + ++G SH+ S R S + S Y + ++S S ++ S R
Sbjct: 2701 DSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTR 2760
Query: 901 SRRHSKRSHDSDDSDYASSKH---------RSKRHKYSSSDDDYSLSCSQSRSRSRSHTR 951
R+ S+ D S +++S+ S R ++S+ S SHT
Sbjct: 2761 GRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTT 2820
Query: 952 ERSR---SRGRSRSSSCSR-SRSKRRSRSTTAHSWQRSRSYS--RDRSRSTRS-PSQRSG 1004
+ R SRG+S S S SR +R++ +S + HS R S D SR +++ Q G
Sbjct: 2821 SQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEG 2880
Query: 1005 SRKR------------SWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDD 1052
SR+ S GH ER SG S+ + + R G ++D
Sbjct: 2881 SRRSRRQGSSVSQDSDSEGHSEDSERWSGS----ASRNHHGSAQEQLRDGSRHPRSHQED 2936
Query: 1053 GRGDDSKA-TGPPSQNSNIGTGRGSEGDCSPEDKNS 1087
G A + S + T G + S E S
Sbjct: 2937 RAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARS 2972
Score = 86.3 bits (212), Expect = 2e-16
Identities = 118/475 (24%), Positives = 185/475 (38%), Gaps = 56/475 (11%)
Query: 649 GSHGSETEDTGRSLPSK------KERSGKSHRHKKKKKHKKS---SKHKRKHKADTEEK- 698
GSH + D R S+ + G S R ++ H++S S H H + T +
Sbjct: 819 GSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQG 878
Query: 699 ---SSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQ 755
+S+ +SG +S R R ++++ + R + S R + Q S+
Sbjct: 879 RSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADIS----RHSQAGQGQSE 934
Query: 756 RRSLPAEEGSSGKKDEGGGGSSSQDH-----GGRKHKGELPPSSCQRRAGTKRSSRSSHR 810
+GSS +D G S R H+G S R G+ R RS H
Sbjct: 935 GSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQS---RHGS-RHPRSHHE 990
Query: 811 SQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSS-HRSSRRS 869
+ G S D+S ++S + ++E + S H ++RS G RH S H+ S S
Sbjct: 991 DRAGHGH--SADSS-----RQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADS 1043
Query: 870 YSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYS 929
S S R + S S SD S HS+ S S + + H+ S
Sbjct: 1044 SRHSGIPRRQASSAVRDSGHWGSSGSQASD-SEGHSEESDTQSVSGHGQDGPHQQSHQES 1102
Query: 930 SSDDDYSLSCSQSRSRSRSHTRERSRS-RGRSRSSSCSRSRS-KRRSRSTTAHSWQRSRS 987
+ D S + T E+S S GR+R+S+ R S ++R ++ HS +
Sbjct: 1103 ARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHS---ASQ 1159
Query: 988 YSRDRSRSTRSPSQRSGSRKRSWGHESPEER--HSGRRDFIRSKIYRSQSPHYFRSGRGE 1045
+D R+ P R G R+ S HE +R HSG + RS + H R
Sbjct: 1160 EGQDTIRA--HPGSRRGGRQGS-HHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSA 1216
Query: 1046 G-PGKKDDGRGDDSKATG----------PPSQNSNIGTGRGSEGDCSPEDKNSVT 1089
+KD GD S+ +G S++S +G + S S +SV+
Sbjct: 1217 SRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVS 1271
Score = 85.1 bits (209), Expect = 5e-16
Identities = 159/743 (21%), Positives = 268/743 (36%), Gaps = 115/743 (15%)
Query: 416 ASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSE 475
+ + + + H +A E + S P+S + AS G S S + T E S
Sbjct: 1607 SERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGH----SAESSRQSGTRHAETSS 1662
Query: 476 PGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTG 535
G A +++ ++ H Q + + +++S+ +G G +
Sbjct: 1663 GGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDS 1722
Query: 536 PFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPL----YFDFKLSRNKDARTK-GTE 590
S +S + + + E + S F +++S ++ + + G
Sbjct: 1723 EGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRT 1782
Query: 591 KPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGS 650
P G H Q D + S+E G+ +R GS+ G GS
Sbjct: 1783 GPSTGGRQRSRHEQARDSSRHSASQE--GQDTIRGH--------PGSSRGGRQ-----GS 1827
Query: 651 HGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKK 710
H ++ D+ SG H H ++ S+ + ++ + + ++ +SG+ S+
Sbjct: 1828 HYEQSVDS-------SGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRH 1880
Query: 711 RKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRR-----AQD-DSQRRSLPAE-- 762
R +++S+ ADS R + G G + PR R +QD DSQ S +E
Sbjct: 1881 SGSR---HHEASSRADSSRHSQ---VGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERW 1934
Query: 763 EGSSGKKDEGGGGSSSQD---HGGRKHK---GELPPSSCQRRAGTKRSSRSSHRSQPSSG 816
GS+ + G S+D H G H+ G + R++GT R + SS R Q +S
Sbjct: 1935 SGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGT-RHTESSSRGQAASS 1993
Query: 817 DEDSDDA------SSHRLHQKSPSQYS--------------------------EEEEEED 844
E + + S H+L S++S E ED
Sbjct: 1994 HEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSED 2053
Query: 845 SGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCY---SRQRSYSDDSYSDYSDRS 901
S ++ ++ ++G SH+ S R S S S Y + ++S S S S
Sbjct: 2054 SDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGG 2113
Query: 902 RRHSKRSHDSDDSDYASSKHRS---------KRHKYSSSDDDYSLSCSQSRSRSRSHTRE 952
R+ S D S +++S+ R S + S+ S SHT
Sbjct: 2114 RQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTS 2173
Query: 953 RSR---SRGRSRSSSCSR-----SRSKRRSRSTTAH-----SWQRSRSYS---RDRSRST 996
+ R SRG+S S S SR +S SR + +H SW S +S + +S
Sbjct: 2174 QGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGP 2233
Query: 997 RSPSQRSGSRKR---SWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDG 1053
R+ R S + S GH ER SG + QS R R + G
Sbjct: 2234 RTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHG 2293
Query: 1054 RGDDSKATGPPSQNSNIGTGRGS 1076
+S N G+ +
Sbjct: 2294 HSAESSRQSGTHHAENSSGGQAA 2316
Score = 80.9 bits (198), Expect = 9e-15
Identities = 137/622 (22%), Positives = 222/622 (35%), Gaps = 129/622 (20%)
Query: 579 SRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSA 638
S+ + ++G + ++++ Q D + S+ E + R G +
Sbjct: 876 SQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRH--HEASSHADISRHSQAGQGQS 933
Query: 639 CSGLNKQEPGGSHGSETEDTGRSLPSKK--ERSGKSHRHKKKKKHKKSSKHKRKHKADTE 696
+ G S +++ G S S++ + ++HR +++ + S+H R H D
Sbjct: 934 EGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRA 993
Query: 697 EKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQR 756
A+S +S ++++ + R E GS R +++ D S+
Sbjct: 994 GHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGS-------RHQQSADSSRH 1046
Query: 757 RSLPAEEGSSGKKDEGGGG------SSSQDH----------------------------- 781
+P + SS +D G G S S+ H
Sbjct: 1047 SGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDW 1106
Query: 782 -GGRKHKG-----------ELPPSSCQRRAGTKRSSRSSHR-----SQPSSGDEDSDDAS 824
GGR + + + + R T R S H S+ S+ E D
Sbjct: 1107 SGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIR 1166
Query: 825 SHRLHQKSPSQYSEEEEEED----SGSEHS------------------------RSRSRS 856
+H ++ Q S E+ D SGS HS R +S
Sbjct: 1167 AHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQS 1226
Query: 857 GRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDY 916
G S H SR ++S SS S +++S R+ RH + S S DSD
Sbjct: 1227 G-DGSRHSGSRHHEAASWADSSRHSQVGQEQS--------SGSRTSRH-QGSSVSQDSD- 1275
Query: 917 ASSKHRSKRHKYSSSDDDYSLSCSQSRSR---SRSHTRERSRSRGRSRSSSCSRSRSKRR 973
S+RH SDD LS S SR+ SR +R+ SR G + S S
Sbjct: 1276 ------SERH----SDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADS 1325
Query: 974 SRSTTAHSWQRSRS----YSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSK 1029
SR + H + S S +++RS SP +R GSR + + RHSG S
Sbjct: 1326 SRQSGTHHTESSSHGQAVSSHEQARS--SPGERHGSRHQ---QSADSSRHSGIGHRQASS 1380
Query: 1030 IYRSQSPHYFRSG----RGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDK 1085
R S H SG EG + D + + P Q S+ + RG G+ S +
Sbjct: 1381 AVR-DSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSR 1439
Query: 1086 NSVTAKLLLEKIQSRKVERKPS 1107
+ + E+ +S + PS
Sbjct: 1440 SFLYQVSSHEQSESTHGQTAPS 1461
Score = 78.2 bits (191), Expect = 6e-14
Identities = 120/489 (24%), Positives = 180/489 (36%), Gaps = 63/489 (12%)
Query: 659 GRSLPSKKERSGKSHRHKKKKKHKK--SSKHKRKHKADTEEKSSKAESGEKSKKR--KKR 714
GRS S +E GK H +KK +K S H+ + SSK E + R R
Sbjct: 139 GRS-KSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNR 197
Query: 715 KRKKNKSSAPADSERGPKP-EPPG--------SGSPAPPRRRRRAQDDSQRRSLPAEEGS 765
KR + D+E G E G SG A + D+ L EE
Sbjct: 198 KRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLL--EENK 255
Query: 766 SGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSR------------------- 806
++ G SS +H+ + R +R SR
Sbjct: 256 IYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSG 315
Query: 807 SSHRSQPSSGDEDSDDASSH-RLH--------------QKSPSQYSEEEEEEDSGSEHSR 851
S+ R+ S E S D S H R H ++S ++++E + S H +
Sbjct: 316 SASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQ 375
Query: 852 SRSRSGRRH-SSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHD 910
+RS G RH S H+ S S S+ S R + S S SD S HS+ S
Sbjct: 376 ARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASD-SEGHSENSDT 434
Query: 911 SDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRS-RGRSRSSSCSRSR 969
S + + R + H+ S+ S S + T E+ S GR+ +S+ R
Sbjct: 435 QSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQG 494
Query: 970 S-KRRSRSTTAHS-WQRSRSYSRDR---SRSTRSPSQRSGSRKRSWGHESPEERHS---G 1021
S ++R ++ HS Q + R SR R S S RS GH H+ G
Sbjct: 495 SHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRS-GHSGSHHSHTTSQG 553
Query: 1022 RRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDG-RGDDSKATGPPSQNSNIGTGRGSEGDC 1080
R D + + R+ G G + G R ++ + S++S +G G+ S
Sbjct: 554 RSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRT 613
Query: 1081 SPEDKNSVT 1089
S +SV+
Sbjct: 614 SRNQGSSVS 622
Score = 77.4 bits (189), Expect = 1e-13
Identities = 134/644 (20%), Positives = 233/644 (36%), Gaps = 74/644 (11%)
Query: 415 RASEQMDGDNTT--HPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTE 472
R S +G +T HP ++ ++GS + + + G+ + + + +
Sbjct: 505 RHSASQEGQDTIRGHPGSSRGGRQGSHHEQS--VNRSGHSGSHHSHTTSQGRSDASHGQS 562
Query: 473 PSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKH 532
S S+ + GD + S H E++S ++S + G+ GP+
Sbjct: 563 GSRSASRQTRNEEQSGDGTRHSGSRHH---------EASSQADSSRHSQVGQGQSSGPR- 612
Query: 533 PTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKP 592
S+++ +++ S+ ++ S S + + +++D G+ P
Sbjct: 613 --------TSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRD----GSRHP 660
Query: 593 KDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHG 652
+ H D S++ G SS G+ A +S + G H
Sbjct: 661 RSHHEDRAGHGHSAD-----SSRKSGTRHTQNSSSGQ--AASSHEQARSSAGERHGSRHQ 713
Query: 653 SETEDTGRSLPSKKERSGKSHR---HKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSK 709
++ D+ R + ++ + R H+ + + +DT+ S ++G +
Sbjct: 714 LQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQ 773
Query: 710 KRKKRKRKKN-----KSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEG 764
++ R ++ +S + K G P R+ Q R
Sbjct: 774 SHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSA 833
Query: 765 SSGKKD--EGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDD 822
S +D G GSS + G H+ + R+G S S SQ S D
Sbjct: 834 SQDGQDTIRGHPGSSRRGRQGSHHEQSVD------RSGHSGSHHSHTTSQGRS------D 881
Query: 823 ASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSC 882
AS + +S S+ + EE+ GS HS SR H+ SR S + + ++
Sbjct: 882 ASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHAD--ISRHSQAGQGQSEGSRTS 939
Query: 883 YSRQRSYSDDSYSD-YSDRSRRHS-KRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCS 940
+ S S DS S+ +S+ S R S S + S S+H S RH S +D S
Sbjct: 940 RRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGS-RHPRSHHEDRAGHGHS 998
Query: 941 QSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPS 1000
SR +S T S G +SS ++RS R + H S D SR + P
Sbjct: 999 ADSSR-QSGTPHAETSSGGQAASSHEQARSSPGERHGSRH------QQSADSSRHSGIPR 1051
Query: 1001 QRSGSRKRSWGH-------ESPEERHSGRRDFIRSKIYRSQSPH 1037
+++ S R GH S E HS D + PH
Sbjct: 1052 RQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPH 1095
Score = 75.9 bits (185), Expect = 3e-13
Identities = 113/515 (21%), Positives = 178/515 (34%), Gaps = 60/515 (11%)
Query: 578 LSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGS 637
+S++ D++ + + GS+S++H + S+ R+ G A S
Sbjct: 3539 VSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHS---AESS 3595
Query: 638 ACSGLNKQE-PGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTE 696
SG + E G + + + RS S ER G H+ H + A
Sbjct: 3596 RQSGTHHAENSSGGQAASSHEQARS--SAGERHGSHHQQSADSSRHSGIGHGQASSA-VR 3652
Query: 697 EKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPG-------------SGSPAP 743
+ + SG ++ + + S A + GP + SGS
Sbjct: 3653 DSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLY 3712
Query: 744 PRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSS-------SQD----HGGRKHKGELPP 792
+ + R+ P+ G G + E SS QD H G + G
Sbjct: 3713 QVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGR--Q 3770
Query: 793 SSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRS 852
S ++ + SH S +S + DAS + +S S+ + EE+ GS HS S
Sbjct: 3771 GSYHEQSVDRSGHSGSHHSHTTS--QGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGS 3828
Query: 853 R-------------SRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSD 899
R S+SG+ S+ SRRS S S D S +Y +DS
Sbjct: 3829 RHHEASTQADSSRHSQSGQGESA--GSRRSRRQGSSVSQD----SDSEAYPEDSERRSES 3882
Query: 900 RSRRH--SKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSR 957
SR H S R D S + S HR SS S ++ S +++ +
Sbjct: 3883 ASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHS 3942
Query: 958 G-RSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWG---HE 1013
G +SR S S S +S T Q + S SG R G +
Sbjct: 3943 GIQSRGSPHSSSSYHYQSEGTERQKGQSGLVWRHGSYGSADYDYGESGFRHSQHGSVSYN 4002
Query: 1014 SPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPG 1048
S R D ++ + P Y+ + + PG
Sbjct: 4003 SNPVVFKERSDICKASAFGKDHPRYYATYINKDPG 4037
Score = 68.9 bits (167), Expect = 3e-11
Identities = 93/435 (21%), Positives = 166/435 (38%), Gaps = 57/435 (13%)
Query: 671 KSHRHKKKKKHKKSSKHK-RKHKADTEEKSSKAESGEKSKKR-----KKRKRKKNKSSAP 724
+++ +K++ S HK RKH + + +K E ++++KR ++ RK NK +
Sbjct: 83 QAYYESTRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSK 142
Query: 725 ADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGR 784
+ E G K S ++ R+ + R + + K E +++ R
Sbjct: 143 SPRETGGKRHESSS-----EKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNR 197
Query: 785 KHKGELPPSSCQRRAG----------TKRSSRSSHRSQPSSGDEDSDDASSHRLHQ---- 830
K E G T++ +S H + + +++ D + L +
Sbjct: 198 KRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIY 257
Query: 831 --------KSPSQYSEEEEEEDS--GSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQ 880
KS SQ + E S + SR+R R G R S R S +S S+ S
Sbjct: 258 ERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDS-EGHSEDSERHSG- 315
Query: 881 SCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCS 940
S R++ ++ D SR RSHD D + + S S++ ++ +
Sbjct: 316 ---SASRNHHGSAWEQSRDGSRH--PRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTA 370
Query: 941 QSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPS 1000
S ++RS ER S G +S+ SR + R ++++A S + R S ++ + S
Sbjct: 371 SSHEQARSSPGERHGS-GHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHS 429
Query: 1001 QRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKA 1060
+ S ++ S GH R ++ R + GE G+ S
Sbjct: 430 ENSDTQSVS-GHGKAGLRQQSHQESTRGR-------------SGERSGRSGSSLYQVSTH 475
Query: 1061 TGPPSQNSNIGTGRG 1075
P S + GT G
Sbjct: 476 EQPDSAHGRTGTSTG 490
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 95.9 bits (237), Expect = 3e-19
Identities = 80/241 (33%), Positives = 112/241 (46%), Gaps = 29/241 (12%)
Query: 802 KRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEH-SRSRSRSGRRH 860
+++S + + S S AS H + + + ++ G +H SRSRS+ GRRH
Sbjct: 14 EKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRH 73
Query: 861 -SSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASS 919
S +SS++ S + S R+R S ++ D R R S R ++ S
Sbjct: 74 ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR-----SHSRS 128
Query: 920 KHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTA 979
+ R +RH+ S S+ R +SRS +RER +SR RSR SRSRS+ R R +
Sbjct: 129 RSRERRHR----------SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRS 178
Query: 980 HSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYF 1039
S RSR R RSRS RS SR R E P R F RS + R+ SP F
Sbjct: 179 RSRSRSRHRHRTRSRS----RTRSRSRDRKKRIEKP-------RRFSRS-LSRTPSPPPF 226
Query: 1040 R 1040
R
Sbjct: 227 R 227
Score = 75.5 bits (184), Expect = 4e-13
Identities = 77/290 (26%), Positives = 123/290 (42%), Gaps = 34/290 (11%)
Query: 723 APADSER-GPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDH 781
A +D+ER G PE +P R +++ Q + ++ S + D+
Sbjct: 2 AASDTERDGLAPE-----KTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDN 56
Query: 782 GGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLH--QKSPSQYSEE 839
GRKH+ S RR +K S H+S+ + E S D RL+ + ++ +
Sbjct: 57 EGRKHRSR-SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRK 115
Query: 840 EEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSD 899
E + G HSRSRSR R S R ++S S S + +S SR+R S S +
Sbjct: 116 ERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRS-RSRERK---KSRSRSRE 171
Query: 900 RSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGR 959
R RR RS + S+HR + S+SR+RSRS R++ + R
Sbjct: 172 RKRRIRSRSR-------SRSRHRHRTR-------------SRSRTRSRSRDRKKRIEKPR 211
Query: 960 SRSSSCSRSRSKRRSRS-TTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKR 1008
S S SR+ S R TA Q + + +R++ + ++ K+
Sbjct: 212 RFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQ 261
Score = 51.2 bits (121), Expect = 7e-06
Identities = 57/233 (24%), Positives = 86/233 (36%), Gaps = 26/233 (11%)
Query: 652 GSETEDTGRSLPSKKERSGKSHRHKKKKKH---KKSSKHKRKHKADTEEKSSKAESGEKS 708
G E T KKE+S S + K H +S +RK K+D E + ++ S K
Sbjct: 10 GLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKE 69
Query: 709 KKR---KKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGS 765
+R K + KK+KS D E S R R + ++ + R E S
Sbjct: 70 GRRHESKDKSSKKHKSEEHNDKEH----------SSDKGRERLNSSENGEDRHKRKERKS 119
Query: 766 SGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASS 825
S + S + H R + + S + R ++ SR +S+ S +
Sbjct: 120 SRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER------K 173
Query: 826 HRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASS 878
R+ +S S+ SR+RSRS R RR S S S
Sbjct: 174 RRIRSRSRSRSRHRHRTRS----RSRTRSRSRDRKKRIEKPRRFSRSLSRTPS 222
Score = 47.8 bits (112), Expect = 8e-05
Identities = 38/191 (19%), Positives = 70/191 (36%), Gaps = 9/191 (4%)
Query: 647 PGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGE 706
P S + RS K++ + +H+ + + K+ +H+ K K+ + KS + E
Sbjct: 33 PRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKE 92
Query: 707 KSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSS 766
S K R+R + + +R + G R RR + S+ R
Sbjct: 93 HSSD-KGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRE 151
Query: 767 GKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSH 826
KK S+ + K +RR ++ SRS HR + S +
Sbjct: 152 RKK--------SRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDR 203
Query: 827 RLHQKSPSQYS 837
+ + P ++S
Sbjct: 204 KKRIEKPRRFS 214
Score = 46.6 bits (109), Expect = 2e-04
Identities = 39/184 (21%), Positives = 72/184 (39%), Gaps = 25/184 (13%)
Query: 577 KLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASG 636
K R +++ K ++K K + K+H S + G E++ S G
Sbjct: 68 KEGRRHESKDKSSKKHKSEEHNDKEH-----------SSDKGRERLNSSENGEDRHKRKE 116
Query: 637 SACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTE 696
K G SH R +ER R +++KK + S+ ++K ++ +
Sbjct: 117 ------RKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR 170
Query: 697 EKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPG------SGSPAPP--RRRR 748
E+ + S +S+ R + + + + +R + E P S +P+PP R R
Sbjct: 171 ERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRN 230
Query: 749 RAQD 752
A D
Sbjct: 231 TAMD 234
Score = 36.2 bits (82), Expect = 0.25
Identities = 43/161 (26%), Positives = 61/161 (37%), Gaps = 13/161 (8%)
Query: 910 DSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSR-SRSHTRERSRSR-----GRSRSS 963
D++ A K R K + S+S S+ SRS +R R R R GR S
Sbjct: 5 DTERDGLAPEKTSPDRDK-KKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRS 63
Query: 964 SCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGR- 1022
SRS+ RR S S + D+ S+ +R S + +ER S R
Sbjct: 64 R-SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRG 122
Query: 1023 ----RDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSK 1059
R R + +RS+S +S KK R + K
Sbjct: 123 RSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERK 163
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 94.7 bits (234), Expect = 6e-19
Identities = 130/489 (26%), Positives = 197/489 (40%), Gaps = 84/489 (17%)
Query: 644 KQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAE 703
+ E S S E+ G +++S H KKKKHK SKHK KHK +EE K
Sbjct: 14 EMEDANSEKSINEENGEV---SEDQSQNKHSRHKKKKHKHRSKHK-KHKHSSEEDKDK-- 67
Query: 704 SGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQD-------DSQR 756
K K + K K+ K K A + G P +R + D + QR
Sbjct: 68 ---KHKHKHKHKKHKRKEIIDASDKEG-----------MSPAKRTKLDDLALLEDLEKQR 113
Query: 757 RSLPAE---EGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSH-RSQ 812
+ AE E GK G G G + +GE+ + R G + S+RSS + +
Sbjct: 114 ALIKAELDNELMEGKVQSGMGLILQGYESGSEEEGEIHEKA---RNGNRSSTRSSSTKGK 170
Query: 813 PSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSE---HSRSRSRSGRRHSSHRSSRRS 869
D + K +++ ++++ G E +RS+S R S S+RS
Sbjct: 171 LELVDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRS 230
Query: 870 YSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYS 929
S A +S R+RS + K +DD K +SK K S
Sbjct: 231 -KSQDQARKSKSPTLRRRS------------QEKIGKARSPTDDKVKIEDKSKSKDRKKS 277
Query: 930 SSDDDYSLSCSQSRSRSRSHTRERSRS----RGRSRSSSCSRSRSKRRSRSTTAHSWQRS 985
++SRSR R ++SRS RG+S+ SRS+ ++ RS T +
Sbjct: 278 P-------IINESRSRDRG---KKSRSPVDLRGKSKDRR-SRSKERKSKRSETDKEKKPI 326
Query: 986 RSYSRDRS--RSTRSPSQRSG--SRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRS 1041
+S S+D S + RSPS+R G ++RS SP+ R RR RS + + +S
Sbjct: 327 KSPSKDASSGKENRSPSRRPGRSPKRRSL---SPKPRDKSRRS--RSPLLNDRRSKQSKS 381
Query: 1042 -GRGEGPGKKDDGRGDDSKATGPPSQ---------NSNIGTGRGSEGDCSPEDKNSVTAK 1091
R PG++ R + K P + +I + R D SP ++ S T +
Sbjct: 382 PSRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRDDILSRRERSKDASPINRWSPTRR 441
Query: 1092 LLLEKIQSR 1100
I+ R
Sbjct: 442 RSRSPIRRR 450
Score = 88.2 bits (217), Expect = 5e-17
Identities = 118/419 (28%), Positives = 167/419 (39%), Gaps = 47/419 (11%)
Query: 636 GSACSGLNKQEPGGSHGSETE--------DTGRSLPSKKERSGK----SHRHKKKKKHKK 683
G SG+ G GSE E + RS GK ++ KK+ K
Sbjct: 127 GKVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKS 186
Query: 684 SSKHKRKHKADTEEKSSKAES-GEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPA 742
SK + +H++D ++ E EK+ + K ++RKK+KS + + K + S +
Sbjct: 187 RSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPS-----KRSKSQDQARKSKS 241
Query: 743 PPRRRRRAQDDSQRRSLPAE----EGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRR 798
P RRR + + RS + E S KD ++ + K P + +
Sbjct: 242 PTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGK 301
Query: 799 AGTKRSSRSSHRSQPSSGDED-------SDDASSHRLHQKSPSQYSEEEEEEDSGSEHSR 851
+ +RS +S+ S D++ S DASS + +SPS+ + S S R
Sbjct: 302 SKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGK-ENRSPSRRPGRSPKRRSLSPKPR 360
Query: 852 SRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDS 911
+SR R S + RRS S S S S R +S S + +R R S R+
Sbjct: 361 DKSRRSR--SPLLNDRRSKQSKSP-SRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPR 417
Query: 912 DDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRS- 970
DD S + RSK D S +R RSRS R RSRS R S RSRS
Sbjct: 418 DD--ILSRRERSK-------DASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSRSP 468
Query: 971 KRRSRSTTAHSWQRSRSYS----RDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDF 1025
+RR R + S R RS S R RSRS + GS E DF
Sbjct: 469 RRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSSDDNLEDF 527
Score = 67.0 bits (162), Expect = 1e-10
Identities = 93/435 (21%), Positives = 152/435 (34%), Gaps = 29/435 (6%)
Query: 750 AQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSH 809
A+ S R E+ +S K G S+D KH R K RS H
Sbjct: 4 AETQSLREQPEMEDANSEKSINEENGEVSEDQSQNKH---------SRHKKKKHKHRSKH 54
Query: 810 RSQPSSGDEDSDDASSHR-LHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRR 868
+ S +ED D H+ H+K + + +++ S R++ R
Sbjct: 55 KKHKHSSEEDKDKKHKHKHKHKKHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRA 114
Query: 869 SYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKY 928
+ D + Y S+ +++ + + S SS + K
Sbjct: 115 LIKAELDNELMEGKVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELV 174
Query: 929 SSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSR--SSSCSRSRSKRRSRSTTAHSWQRSR 986
+ S S+S+ R+R H ++ +S+G +RS+SK R +S + R
Sbjct: 175 DNKITTKKRSKSRSKERTR-HRSDKKKSKGGIEIVKEKTTRSKSKERKKSKS----PSKR 229
Query: 987 SYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEG 1046
S S+D++R ++SP+ R S+++ SP + D +SK R +SP R
Sbjct: 230 SKSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSK-DRKKSP-IINESRSRD 287
Query: 1047 PGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKP 1106
GKK D G + R S+ S DK K + S K R P
Sbjct: 288 RGKKSRSPVD---LRGKSKDRRSRSKERKSKR--SETDKEKKPIKSPSKDASSGKENRSP 342
Query: 1107 SVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLGNKPVLPLIGKLPATRKPNKKCEESGL 1166
S PK +D + P L + P T P ++ + L
Sbjct: 343 SRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSP-----SRTLSPGRRAKSRSL 397
Query: 1167 ERGEEQEQSETEEGP 1181
ER + + P
Sbjct: 398 ERKRREPERRRLSSP 412
Score = 52.4 bits (124), Expect = 3e-06
Identities = 105/509 (20%), Positives = 189/509 (37%), Gaps = 56/509 (11%)
Query: 418 EQMDGDNTTHPKNAPESKKGS---SPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPS 474
E +D TT ++ SK+ + S K KS K EKT S++ K+
Sbjct: 172 ELVDNKITTKKRSKSRSKERTRHRSDKKKS--KGGIEIVKEKTTRSKSKERKK------- 222
Query: 475 EPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPT 534
SK+ +K++ D + +S ++ S+ ++ ++ S + + +S++ K P
Sbjct: 223 ---SKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPI 279
Query: 535 GPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKD 594
S+D + P +L +K S S K R++ ++ K
Sbjct: 280 --INESRSRDRGKKSRSPVDLRGKSKDRRSRS------------KERKSKRSETDKEKKP 325
Query: 595 IGSSSKDHLQGLD-------PGEPNKSKEVGG---EKIVRSSGGRMDAPASGSACSGLNK 644
I S SKD G + PG K + + +K RS ++ S + S
Sbjct: 326 IKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSRT 385
Query: 645 QEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAES 704
PG S + + R P ++ S + + + S+ +R A + S
Sbjct: 386 LSPGRRAKSRSLERKRREPERRRLSSP----RTRPRDDILSRRERSKDASPINRWSPTRR 441
Query: 705 GEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLP--AE 762
+S R++ + +S +P R P+ G S + RRR R++ +RRS E
Sbjct: 442 RSRSPIRRRSRSPLRRSRSPRRRSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKE 501
Query: 763 EGSSGKKDEG---GGGSSSQDH------GGRKHKGELPPSSCQRRAGTKRSSRSSHRSQP 813
+ G EG SSS D+ + + QR+A ++ + S
Sbjct: 502 DKFKGSLSEGMKVEQESSSDDNLEDFDVEEEDEEALIEQRRIQRQAIVQKYKYLAEDSNM 561
Query: 814 SSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSS 873
S E S SS R SP E + E+ R + + + + +
Sbjct: 562 SVPSEPSSPQSSTRTRSPSPDDILERVAAD--VKEYERENVDTFEASVKAKHNLMTVEQN 619
Query: 874 SDASSDQSCYSRQRSYSDDSYSDYSDRSR 902
+ +S + + SDD ++ Y D +R
Sbjct: 620 NGSSQKKLLAPDMFTESDDMFAAYFDSAR 648
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 94.7 bits (234), Expect = 6e-19
Identities = 100/379 (26%), Positives = 144/379 (37%), Gaps = 34/379 (8%)
Query: 660 RSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEE--KSSKAESGEKSKKRKKRKRK 717
RS + +RS RH + S ++ H + +E +S + +R
Sbjct: 1567 RSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLS 1626
Query: 718 KNKSSAPAD-SERGP---KPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGG 773
+ +P+ S RGP + P S P R +R P++ G +
Sbjct: 1627 ERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSH 1686
Query: 774 GGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSP 833
S + H + PS + + +KRS RS R S E S + S R H SP
Sbjct: 1687 CSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHH-SP 1745
Query: 834 SQ---YSEEEEEEDSGSEHS-------RSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCY 883
S+ +S E S SE S R RS S RRH H S +S+ S S+ S
Sbjct: 1746 SERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRH--HSPSEKSHHSPSERSHHSPSE 1803
Query: 884 SRQRSYSDDSYSDYSDRSRR--HSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQ 941
R+ S + S +RS R +RSH S + S R +S S+ + +
Sbjct: 1804 RRRHSPLERSRHSLLERSHRSPSERRSHRS----FERSHRRISERSHSPSEKSHLSPLER 1859
Query: 942 SRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRS--RSYSRDRSRSTRSP 999
SR S RG S S S S+R RS + R+ RS+ R+ SP
Sbjct: 1860 SRC-------SPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSP 1912
Query: 1000 SQRSGSRKRSWGHESPEER 1018
S+ R H SP ER
Sbjct: 1913 SEMRPGRPSGRNHCSPSER 1931
Score = 84.0 bits (206), Expect = 1e-15
Identities = 115/432 (26%), Positives = 167/432 (38%), Gaps = 40/432 (9%)
Query: 698 KSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRR---RRAQD-- 752
++ + +S +SKK R ++ S S G + + G P P +R R +D
Sbjct: 1476 RTVQKDSSSRSKKNFYRNETSSQESKNL-STPGTRVQARGRILPGSPVKRTWHRHLKDKL 1534
Query: 753 ---DSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSH 809
+ S E G + S ++H + + + + ++RS S
Sbjct: 1535 THKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPS 1594
Query: 810 RSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRS-RSRSGRRHSSHRSSRR 868
R SS E S + S R H P + E S RS R S RRH H S R
Sbjct: 1595 RKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRH--HSPSER 1652
Query: 869 SYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRS---KR 925
S+ S S+ S S R RS S S+ R S+RSH S + +HRS +
Sbjct: 1653 SHRSPSERSHRSSSERRHRSPSQRSH-------RGPSERSHCSP----SERRHRSPSQRS 1701
Query: 926 HKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRR--SRSTTAHSWQ 983
H+ S +S S RS +R R S S S S S+RR S S +H
Sbjct: 1702 HRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSP 1761
Query: 984 RSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEER--HSGRRDFIRSKIYRSQSPHYFRS 1041
RS+ R RSPS+R H SP ER HS S + RS+ RS
Sbjct: 1762 SERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERS 1821
Query: 1042 GRGEGPGKKDDGRGDD------SKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLE 1095
R P ++ R + S+ + PS+ S++ S CSP ++ ++
Sbjct: 1822 HR--SPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSR--CSPSERRGHSSSGKTC 1877
Query: 1096 KIQSRKVERKPS 1107
S + R PS
Sbjct: 1878 HSPSERSHRSPS 1889
Score = 83.6 bits (205), Expect = 1e-15
Identities = 135/586 (23%), Positives = 211/586 (36%), Gaps = 75/586 (12%)
Query: 452 QGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKKA-LGGDVSDQSLESHSQKVSETQMCES 510
+ A++ S QP+ + +P++ S + A +G + +S S+ E+
Sbjct: 1436 RSAQQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNET 1495
Query: 511 NSSKETSLATPAGKESQEG---PKHPTGPFFPVLSKDESTALQW--PSELLIFTKAEPSI 565
+S + +L+TP + G P P + KD+ T + PS T PS
Sbjct: 1496 SSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSE 1555
Query: 566 SYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRS 625
NP + + + + R+ + + + S + H P N S E+ RS
Sbjct: 1556 RTRHNPSWRNHRSPSERSQRS--SLERRHHSPSQRSHCS---PSRKNHSSP--SERSWRS 1608
Query: 626 SGGRMDAPASGSACSGLNKQEPGGSHG-SETEDTGRSLPSKKERSGKSHRHKKKKKHKKS 684
R +C L+++ G H S+ G S S +SHR ++ H+ S
Sbjct: 1609 PSQRNHCSPPERSCHSLSER---GLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSS 1665
Query: 685 SKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPP 744
S+ R+H++ ++ ++R R ++ S SER + P S P
Sbjct: 1666 SE--RRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSER--RHHSPSKRSHRSP 1721
Query: 745 RRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRS 804
RR + P+E + S + H + PS + R+ ++R
Sbjct: 1722 ARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERR 1781
Query: 805 SRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSR-SRSRSGRRHSSH 863
S PS S SH +S E S E SR S R S
Sbjct: 1782 HHS-----PSEKSHHSPSERSH---------HSPSERRRHSPLERSRHSLLERSHRSPSE 1827
Query: 864 RSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRS 923
R S RS+ S RR S+RSH + + S RS
Sbjct: 1828 RRSHRSFERS---------------------------HRRISERSHSPSEKSHLSPLERS 1860
Query: 924 K----RHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTA 979
+ + SS S S+ RS S R+ R+ RS SSC R+ R S S
Sbjct: 1861 RCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQ-GRTSERSHRSSCERT---RHSPSEMR 1916
Query: 980 HSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDF 1025
R++ RS RSP + K S+ E P HS RDF
Sbjct: 1917 PGRPSGRNHCSPSERSRRSPLKE--GLKYSFPGERPS--HSLSRDF 1958
Score = 41.6 bits (96), Expect = 0.006
Identities = 63/233 (27%), Positives = 93/233 (39%), Gaps = 35/233 (15%)
Query: 898 SDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRS- 956
S+R+R + + S+ + +RH +S S + CS SR ++H+ RS
Sbjct: 1554 SERTRHNPSWRNHRSPSERSQRSSLERRH-HSPSQRSH---CSPSR---KNHSSPSERSW 1606
Query: 957 RGRSRSSSCS------RSRSKR--RSRSTTAHSWQRSRSYSRDRSRSTRSPSQRS---GS 1005
R S+ + CS S S+R S S +H R + RS RSPS+RS S
Sbjct: 1607 RSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSS 1666
Query: 1006 RKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPS 1065
+R H SP +R S R RS S+ H S R RG + PS
Sbjct: 1667 ERR---HRSPSQR-SHRGPSERSHCSPSERRHRSPSQRSH--------RGPSERRHHSPS 1714
Query: 1066 QNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNK 1118
+ S+ R S S +S + + S R S SE +P++
Sbjct: 1715 KRSHRSPARRSHRSPSERSHHSPSER----SHHSPSERRHHSPSERSHCSPSE 1763
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 91.7 bits (226), Expect = 5e-18
Identities = 131/499 (26%), Positives = 170/499 (34%), Gaps = 50/499 (10%)
Query: 619 GEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDT-GRSLPSKKERSGKSH-RHK 676
G + +SS G +SGS+ S G HGS + + G R SH RH
Sbjct: 261 GSRSGQSSRGERHRSSSGSSSSY-------GQHGSGSRQSLGHGRQGSGSRQSPSHVRHG 313
Query: 677 KKKKHKKS-----SKHKRKHKADTEEKSSKAESG---EKSKKRKKRKRKKNKSSAPADSE 728
H S S + E S SG +S + K+ S + S
Sbjct: 314 SGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSS 373
Query: 729 RGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKG 788
+G G S + Q S + A SSG+ G S HG R
Sbjct: 374 QGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGS 433
Query: 789 ELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDA-SSHRLHQKSPSQYSEEEEEEDSGS 847
PSS Q G RSS SSG S SS H +S S++S + SGS
Sbjct: 434 GQSPSSGQHGTGFGRSS--------SSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGS 485
Query: 848 EHS---------RSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYS 898
HS +S G R S S SY S +SR S S S S
Sbjct: 486 GHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSR 545
Query: 899 DRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRG 958
R S++S Y S + S+ S S L +SRS S + S G
Sbjct: 546 GRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSG 605
Query: 959 RSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEER 1018
S S+ + +S S H +S S + S S S R G + G R
Sbjct: 606 HS-STHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGR 664
Query: 1019 HSGRRDFIRSKIY----------RSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNS 1068
H DF S Y S PH SG+ G G K G G S + S +S
Sbjct: 665 HGS--DFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHK-SGSGQSSGYSQHGSGSS 721
Query: 1069 NIGTGRGSEGDCSPEDKNS 1087
+ +G G S + S
Sbjct: 722 H-SSGYRKHGSRSGQSSRS 739
Score = 91.7 bits (226), Expect = 5e-18
Identities = 132/521 (25%), Positives = 178/521 (34%), Gaps = 51/521 (9%)
Query: 596 GSSSKDHLQGLDPGEPNK-------SKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPG 648
G SS+ QG G + S++ G S G+ +P+ G SG +
Sbjct: 499 GQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSY 558
Query: 649 GSHGSETEDTGRSLPSKKERSGKSHR----HKKKK--------KHKKSSKHKRKHKADTE 696
G HG +GRS SG H H++ + +H SS H H
Sbjct: 559 GPHGY---GSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGS 615
Query: 697 EKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQR 756
+ G+ + S + S R + GSGS P R R D
Sbjct: 616 TSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQ---GSGSGQSPSRGRHGSDFGHS 672
Query: 757 RSLPAEEGSSG-KKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSS 815
S SG G GS S G HK SS + G+ S S +R S
Sbjct: 673 SSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSR 732
Query: 816 GDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSD 875
+ SS S S S + SGS S R G S H SR + SSS
Sbjct: 733 SGQ-----SSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSG-SGHSPSRVRHGSSSG 786
Query: 876 ASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDY 935
SS + S S S Y S + S S S+H S +SS
Sbjct: 787 HSSSHGQHGSGTSCSS-SCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHG 845
Query: 936 SLSCSQSRSRSRSHTRERSRSRGRSRSSS---CSRSRSKRRSRSTTAHSWQ-----RSRS 987
S S S S + +S S G+ S+S R R S + H + +S S
Sbjct: 846 STSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPS 905
Query: 988 YSRDRSRSTRSPSQ-RSGS---RKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGR 1043
Y R S S RS S R GS + +GH+S + SG + + S Y + G
Sbjct: 906 YGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSG---YTQHGSGSGHSSSYEQHGS 962
Query: 1044 GEGPGKKDDGRGDDSKAT---GPPSQNSNIGTGRGSEGDCS 1081
G + + G S ++ G S G G G S
Sbjct: 963 RSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 1003
Score = 84.3 bits (207), Expect = 8e-16
Identities = 133/540 (24%), Positives = 181/540 (33%), Gaps = 100/540 (18%)
Query: 624 RSSGGRMDAPASGSACSGLNKQEPGGSHGS---ETEDTGRSLPSKKE------------- 667
R SG R +P+ G SG + G HGS E+ G S +
Sbjct: 1131 RGSGSRQ-SPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH 1189
Query: 668 ---------RSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRK- 717
RSG+S R ++ SS H +H + + + S G S R R
Sbjct: 1190 SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHG 1249
Query: 718 ----------KNKSSAPADSERGPKPEPPG----------------------SGSPAPPR 745
++ S + S RGP G SGS
Sbjct: 1250 SGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCS 1309
Query: 746 RRRRAQDDSQRRSLPAEEGSSGKKDEGG--GGSSSQDHGGRKHKGELPPSSCQRRAGTKR 803
+ + Q + E S+G+ G G SSQ G +H S + R G+
Sbjct: 1310 QGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSG- 1368
Query: 804 SSRSSHRSQPSSGDEDSDDASSHRL---------HQKSPSQYSEEEEEEDSGSEHSRSRS 854
S SS Q SG S + H H +S S S + SGS HS S
Sbjct: 1369 SGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYE 1428
Query: 855 RSGRRHS-SHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDD 913
+ G R S R R SS S +S Q ++S + S +S S+ H S
Sbjct: 1429 QHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS 1488
Query: 914 SDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRR 973
+S +SSS Y S S +R S SS S + +
Sbjct: 1489 GQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQ 1548
Query: 974 SRSTTAHSWQ-----RSRSYSRDRSRSTRSPSQRSG-SRKRSWGHESP--EERHSGRRDF 1025
ST+ S S S + SQ SG R+ S +SP +R SG R
Sbjct: 1549 HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR-- 1606
Query: 1026 IRSKIYRSQSPHYFRSGRGEG----PGKKDDGRGDDS------KATGPPSQNSNIGTGRG 1075
QSP Y R G G G G+ G G+ S ++G S S G+G G
Sbjct: 1607 --------QSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSG 1658
Score = 84.0 bits (206), Expect = 1e-15
Identities = 122/487 (25%), Positives = 162/487 (33%), Gaps = 41/487 (8%)
Query: 598 SSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETED 657
SS QG G G SS G+ + S S+ G + G + G +
Sbjct: 762 SSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHE 821
Query: 658 TGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRK 717
+G + S H + + S + + D+ S + +S R
Sbjct: 822 SGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRG 881
Query: 718 KNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGG--G 775
++ S + G + GSGS P R S R S GS + G G
Sbjct: 882 RHGSGSGQSPGHGQR----GSGSGQSPSYGRHGSG-SGRSSSSGRHGSGSGQSSGFGHKS 936
Query: 776 SSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQ 835
SS Q G +H SS + G+ RS +SS Q S S H S S+
Sbjct: 937 SSGQSSGYTQHGSGSGHSSSYEQHGS-RSGQSSRSEQHGSSSGSSSSYGQHG----SGSR 991
Query: 836 YSEEEEEEDSGSEHSRSRSRSGRRHSS---HRSSRRSYSSSSDASSDQSCYSRQRSYSDD 892
S + SGS S S SR RH S SS Y S S SS + Y +S
Sbjct: 992 QSLGHGQHGSGSGQSPSPSRG--RHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHS-- 1047
Query: 893 SYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRE 952
S R S+ S + SS S H S S SC Q + S +
Sbjct: 1048 -----SGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH 1102
Query: 953 RSRSRGRSRSSSCSRSRS---KRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRS 1009
G S+SS R S + ++S SY R S S RS S SG
Sbjct: 1103 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSS--SGQHGSG 1160
Query: 1010 WGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSN 1069
G S H QS Y + G G G G G +G S+
Sbjct: 1161 LGESSGFGHHESS---------SGQSSSYSQHGSGSG---HSSGYGQHGSRSGQSSRGER 1208
Query: 1070 IGTGRGS 1076
G+ GS
Sbjct: 1209 HGSSSGS 1215
Score = 83.6 bits (205), Expect = 1e-15
Identities = 139/567 (24%), Positives = 187/567 (32%), Gaps = 94/567 (16%)
Query: 596 GSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDA-----PASGSACSGLNKQEPGGS 650
G SS+ G G + + G S GR + P+ G SGL G
Sbjct: 1201 GQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQ 1260
Query: 651 HGSET----------EDTGRSLPSKKERSGKSHRHKKKKKHKKSSKH---KRKHKADTEE 697
HGS + +G S + SG H +H S H + +H + + +
Sbjct: 1261 HGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHS-SAYSQHGSGSGHFCSQGQHGSTSGQ 1319
Query: 698 KSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRR 757
S+ + G + + + + SS + R G+GS P R R
Sbjct: 1320 SSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRH------GAGSGQSPSRGRHGSGSGHSS 1373
Query: 758 SLPAEEGSSGKKDEGG--GGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRS---- 811
S SG G G S Q G H+ SS Q T+ S S H S
Sbjct: 1374 SYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHES----SSWQSSGCTQHGSGSGHSSSYEQ 1429
Query: 812 ------QPSSGDE---DSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSS 862
Q S G+ S +SS+ H S S+ S + SGS S S SR S
Sbjct: 1430 HGSRSGQSSRGERHGSSSGSSSSYGQHG-SGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS 1488
Query: 863 HRSSRRS-YSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKH 921
+SS S Y S S SS + Y S+S S R S+ S + SS
Sbjct: 1489 GQSSSYSPYGSGSGWSSSRGPYESGSSHS-------SGLGHRESRSGQSSGYGQHGSSSG 1541
Query: 922 RSKRHKYSSSDDDYSLSCSQ---SRSRSRSHTRE---RSRSRGRSRSSSCS--------R 967
S H S S SC Q S +S SH + S+S G R S S R
Sbjct: 1542 HSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQR 1601
Query: 968 SRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHS------- 1020
R+S S H RS S + S S G + S G S +H
Sbjct: 1602 GSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSS 1661
Query: 1021 --------------GRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDG------RGDDSKA 1060
G R S+ H S + G G++ G RG
Sbjct: 1662 GYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSG 1721
Query: 1061 TGPPSQNSNIGTGRGSEGDCSPEDKNS 1087
G S + G+G G P + S
Sbjct: 1722 LGHSSSHGQHGSGSGRSSSRGPYESRS 1748
Score = 82.8 bits (203), Expect = 2e-15
Identities = 128/540 (23%), Positives = 180/540 (33%), Gaps = 60/540 (11%)
Query: 596 GSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRM-----DAPASGSACSGLNKQEPGGS 650
G SS G G+ + + G S GR +P G SG + G
Sbjct: 1554 GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 1613
Query: 651 HGS---ETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRK--HKADTEEKSSKAESG 705
HGS + +G+ E SG H + S+H H + + S++
Sbjct: 1614 HGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQS 1673
Query: 706 EKSKKRKKRKRKKNKSSAPADSERGPKPEP-PGSGSPAPPRRRRRAQDDSQRRSLPAEEG 764
+ ++ R ++ R GSGS P R R S
Sbjct: 1674 SRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGS 1733
Query: 765 SSGKKDEGGGGSSSQDHGG--RKHKGELPPSSCQRRAGT------KRSSRSSHRSQPSSG 816
SG+ G S H +H+ SS + G+ + S Q S+
Sbjct: 1734 GSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF 1793
Query: 817 DEDSDD---ASSHRLHQKSPSQYSEEEEE-EDSGSEHSRSRSRSGRRHSS---HRSSRRS 869
D++ +SSH H SQ S ++ SG SR R SG HSS S
Sbjct: 1794 DQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSG 1853
Query: 870 YSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYS 929
+SSSS S S + + S S ++ S H S + S +S R +
Sbjct: 1854 WSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQH 1913
Query: 930 SSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHS-------W 982
S S S Q S SR G +S S SR R S ++++ W
Sbjct: 1914 GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGW 1973
Query: 983 QRSRSYSRDRS--------RSTRS-PSQRSGSRKRSWGHESPEERH---SGRRDFI---- 1026
SR S R +RS S G S GH S +H SG+
Sbjct: 1974 SSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHG 2033
Query: 1027 ----RSKIY------RSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGS 1076
+S + SQS Y R G G G RG S+ + P G+GR S
Sbjct: 2034 ASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQS-PSYGRHGSGSGRSS 2092
Score = 81.3 bits (199), Expect = 7e-15
Identities = 119/504 (23%), Positives = 167/504 (33%), Gaps = 45/504 (8%)
Query: 589 TEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPG 648
T+ G SS G G+ ++S++ G SS G+ SGS S + Q
Sbjct: 945 TQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQH---GSGSRQSLGHGQHGS 1001
Query: 649 GSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKS 708
GS S + GR SG+S + + S + +++ + S +S
Sbjct: 1002 GSGQSPSPSRGRH----GSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGH--RES 1055
Query: 709 KKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGK 768
+ + ++ SS+ S G G S Q S + SSG
Sbjct: 1056 RSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGY 1115
Query: 769 KDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRL 828
+G G S HG R PS + +G S RSS Q SG +S H
Sbjct: 1116 GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSG---SGRSSSSGQHGSGLGESSGFGHHES 1172
Query: 829 HQKSPSQYSEEEEEEDSGSEHSRSRSRSGR-----RHSSHRSSRRSYSSSSDASSDQSCY 883
S YS+ S + + SRSG+ RH S S Y S S +
Sbjct: 1173 SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGH 1232
Query: 884 SRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSR 943
RQ S S S S R R S H S + S RS S +S Q
Sbjct: 1233 GRQGSGSGHSPS----RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHE 1288
Query: 944 SRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRS 1003
S S H+ S+ G CS+ + H +S + D+ S+ S
Sbjct: 1289 SGS-GHSSAYSQ-HGSGSGHFCSQGQ----------HGSTSGQSSTFDQEGSSTGQSSSY 1336
Query: 1004 GSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGP 1063
G R S RH QSP R G G G G +G
Sbjct: 1337 GHRGSGSSQSSGYGRHGAG---------SGQSPSRGRHGSGSG---HSSSYGQHGSGSGW 1384
Query: 1064 PSQNSNIGTGRGSEGDCSPEDKNS 1087
S + G+G G + +S
Sbjct: 1385 SSSSGRHGSGSGQSSGFGHHESSS 1408
Score = 81.3 bits (199), Expect = 7e-15
Identities = 115/478 (24%), Positives = 157/478 (32%), Gaps = 43/478 (8%)
Query: 612 NKSKEVGGEKIVRSSGGRMDAPASGSACS----GLNKQEPGGSHGSETEDTGRSLPSKKE 667
+ S E G + +SS G +SGS+ S G ++ G HG +G+S +
Sbjct: 2364 SSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLG-HGQHGSGSGQSPSPSRG 2422
Query: 668 RSGKSHRHKKKKKHKKSSKHKRKHKADTEEKS--SKAESGEKSKKRKKRKRKKNKSSAPA 725
R G S + E S S +S+ + ++ SS+
Sbjct: 2423 RHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGH 2482
Query: 726 DSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRK 785
S G G S Q S + SSG +G G S HG R
Sbjct: 2483 SSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 2542
Query: 786 HKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDS 845
PS + +G S RSS Q SG +S H S YS+
Sbjct: 2543 SGSRQSPSYGRHGSG---SGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH 2599
Query: 846 GSEHSRSRSRSGR-----RHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDR 900
S + + SRSG+ RH S S Y S S + RQ S S S S R
Sbjct: 2600 SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPS----R 2655
Query: 901 SRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRS 960
R S H S + S RS S +S Q S S H+ S+ G
Sbjct: 2656 GRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGS-GHSSAYSQ-HGSG 2713
Query: 961 RSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHS 1020
CS+ + H +S + D+ S+ S G R S RH
Sbjct: 2714 SGHFCSQGQ----------HGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHG 2763
Query: 1021 GRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEG 1078
QS + R G G G + G +G S S G+G G +G
Sbjct: 2764 AG---------SGQSLSHGRHGSGSG---QSSSYGQHGSGSGQSSGYSQHGSGSGQDG 2809
Score = 80.5 bits (197), Expect = 1e-14
Identities = 114/457 (24%), Positives = 155/457 (33%), Gaps = 56/457 (12%)
Query: 636 GSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADT 695
G SG + G HGS + + S + SG+S + K S +H + +
Sbjct: 193 GQCGSGSGQSPNYGQHGSGSGQSS-SNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGS 251
Query: 696 EEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQ 755
S + G +S + + +R ++ S + + + G R++ +
Sbjct: 252 GHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVR 311
Query: 756 RRSLPAEEGSSGKKDEGGGGSSSQDH-----GGRKHKGELPPSSCQRRAGTKRSSRSSHR 810
S S G+ G S S+ H G G+ S Q +K S S H
Sbjct: 312 HGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHS 371
Query: 811 SQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSR--SGRRHSSHRSSRR 868
S S ASS H S S+ S + +S S HS R + SG S R
Sbjct: 372 SSQGQHGSTSGQASSSGQHGSS-SRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRG 430
Query: 869 SYSSSSDASSDQSCYSRQRSYSDDSY---SDYSDRSRRH-SKRSHDSDDSDYASSKHRSK 924
S S S SS Q RS S Y S YS H S H S + + S S
Sbjct: 431 SGSGQS-PSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSS 489
Query: 925 RHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQR 984
H + SRS R +G S SS S + SR + H
Sbjct: 490 GH---------------GQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGH---- 530
Query: 985 SRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRG 1044
SR S S +SPS G HES + S S PH + SGR
Sbjct: 531 ----SRHGSGSGQSPSPSRGR------HESGSRQSS------------SYGPHGYGSGRS 568
Query: 1045 EGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCS 1081
G + G G S G S +G G G S
Sbjct: 569 SSRGPYESGSG-HSSGLGHQESRSGQSSGYGQHGSSS 604
Score = 80.1 bits (196), Expect = 1e-14
Identities = 119/475 (25%), Positives = 167/475 (35%), Gaps = 43/475 (9%)
Query: 626 SGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSS 685
S G +P G SG + G HG+ GRS S SG + H+ SS
Sbjct: 417 SSGSGQSPGHGQRGSGSGQSPSSGQHGT---GFGRSSSSGPYVSGSGYS-SGFGHHESSS 472
Query: 686 KHKR---KHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPA 742
+H +H + + S + G +S + + +R+ SSA + S G GSGS
Sbjct: 473 EHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQG--SSAGSSSSYGQH----GSGSRQ 526
Query: 743 PPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTK 802
R Q S SG + G G +G S
Sbjct: 527 SLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGH 586
Query: 803 RSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSE-EEEEEDSGSEHSRSRSRSGRRHS 861
+ SRS S S +S+H H + Q S + SG S + SG S
Sbjct: 587 QESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQS 646
Query: 862 SHRSSRRSYSSSSDASSDQ-SCYSRQRSYSDD-SYSDYSDRSRRHSKRSHDSDDSDYASS 919
S + S S S + S + SY S S +S + H S S + S
Sbjct: 647 SRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSG 706
Query: 920 KHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTA 979
+S + S +S + SRS + SRS SS S S + S S
Sbjct: 707 SGQSSGYSQHGSGSSHSSGYRKHGSRSG----QSSRSEQHGSSSGLSSSYGQHGSGS--- 759
Query: 980 HSWQRSRSYSRDRSRSTRSPSQ-RSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHY 1038
+S + R S S SPS+ R GS S GH S +H S S S +
Sbjct: 760 ---HQSSGHGRQGSGSGHSPSRVRHGS---SSGHSSSHGQHG-------SGTSCSSSCGH 806
Query: 1039 FRSGRGE--GPGKKDDGRG----DDSKATGPPSQNSNIGTGRGSEGDCSPEDKNS 1087
+ SG G+ G G+ + G G A+G S G+ G D +S
Sbjct: 807 YESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSS 861
Score = 80.1 bits (196), Expect = 1e-14
Identities = 118/482 (24%), Positives = 167/482 (34%), Gaps = 45/482 (9%)
Query: 619 GEKIVRSSGGRMDAPASGSACS----GLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHR 674
G + +SS G +SGS+ G ++ G HG + +G S + SG H
Sbjct: 2137 GSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSG-HGRQGSGSGHSPSRGRHGSGSGHS 2195
Query: 675 HKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPE 734
+ S + + ++ S +S ++ S + +G
Sbjct: 2196 SSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGS 2255
Query: 735 PPGSGSPAPPRRRRRAQDDS--QRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPP 792
G S Q S Q S ++ S G++ G G S S+ GR G
Sbjct: 2256 TSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSR---GRHGSGSGHS 2312
Query: 793 SSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRS 852
SS + S SS R SG SS H +S S S + SGS HS S
Sbjct: 2313 SSYGQHGSGSGWSSSSGRHGSGSGQ------SSGFGHHESSSWQSSGYTQHGSGSGHSSS 2366
Query: 853 RSRSGRRHS-SHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDS 911
+ G R S R R SS S +S Q ++S + S +S S+ H S
Sbjct: 2367 YEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGS 2426
Query: 912 DDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSK 971
+S +SSS Y S +R S SS S +
Sbjct: 2427 GSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 2486
Query: 972 RRSRSTTAHSWQ-----RSRSYSRDRSRSTRSPSQRSG-SRKRSWGHESP--EERHSGRR 1023
+ ST+ S S S + SQ SG R+ S +SP +R SG R
Sbjct: 2487 GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 2546
Query: 1024 DFIRSKIYRSQSPHYFRSGRGEG----PGKKDDGRGDDS------KATGPPSQNSNIGTG 1073
QSP Y R G G G G+ G G+ S ++G S S G+G
Sbjct: 2547 ----------QSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG 2596
Query: 1074 RG 1075
G
Sbjct: 2597 SG 2598
Score = 77.8 bits (190), Expect = 7e-14
Identities = 134/541 (24%), Positives = 186/541 (34%), Gaps = 102/541 (18%)
Query: 624 RSSGGRMDAPASGSACSGLNKQEPGGSHGS---ETEDTGRSLPSKKE------------- 667
R SG R +P+ G SG + G HGS E+ G S +
Sbjct: 1601 RGSGSRQ-SPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH 1659
Query: 668 ---------RSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRK- 717
RSG+S R ++ +SS +H + + + S G S + R R
Sbjct: 1660 SSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHG 1719
Query: 718 ----------KNKSSAPADSERGPKPEPPG----------------------SGSPAPPR 745
++ S + S RGP G SGS
Sbjct: 1720 SGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCS 1779
Query: 746 RRRRAQDDSQRRSLPAEEGSSGKKDE----GGGGSSSQDHGGRKHKGELPPSSCQRRAGT 801
+ + Q + E S+G+ G G S S +G + PS + +G+
Sbjct: 1780 QGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGS 1839
Query: 802 KRSSR-SSHRS----QPSSGDEDSDDASSHRL-HQKSPSQYSEEEEEEDSGSEHSRSRSR 855
SS H S SSG S S H +S S S + SGS HS S +
Sbjct: 1840 GHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQ 1899
Query: 856 SGRRHS-SHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDS 914
G R S R + SS S +S Q ++S + S +S S+ H S
Sbjct: 1900 HGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSG 1959
Query: 915 DYAS-------SKHRSKRHKY-SSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCS 966
+S S S R Y S S L +SRS S + S G S S+
Sbjct: 1960 QSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHS-STHGQ 2018
Query: 967 RSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESP--EERHSGRRD 1024
+ +S S H +S S + S S S G R+ S +SP +R SG R
Sbjct: 2019 HGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG-RQGSGSGQSPGHGQRGSGSR- 2076
Query: 1025 FIRSKIYRSQSPHYFRSGRG---------EGPG-KKDDGRGDDSKATGPPSQNSNIGTGR 1074
QSP Y R G G GPG + G G ++G S S G+G
Sbjct: 2077 ---------QSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGS 2127
Query: 1075 G 1075
G
Sbjct: 2128 G 2128
Score = 76.3 bits (186), Expect = 2e-13
Identities = 118/504 (23%), Positives = 168/504 (33%), Gaps = 33/504 (6%)
Query: 596 GSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRM-----DAPASGSACSGLNKQEPGGS 650
G SS G G+ + + G S GR +P G SG + G
Sbjct: 1084 GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 1143
Query: 651 HGSETEDTGRSLPSKKERSG--KSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKS 708
HGS +GRS S + SG +S + S +H + + S + G +S
Sbjct: 1144 HGS---GSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS 1200
Query: 709 KKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGK 768
+ + +R + SS+ + S G GSGS R++ ++ S S G+
Sbjct: 1201 GQSSRGER--HGSSSGSSSHYGQH----GSGS-------RQSSGHGRQGSGSGHSPSRGR 1247
Query: 769 KDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRL 828
G G SSS HG G S R RS SS Q SG S S H
Sbjct: 1248 HGSGLGHSSS--HG---QHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGS 1302
Query: 829 HQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHS-SHRSSRRSYSSSSDASSDQSCYSRQR 887
+ S + S +G+ S HR S S SS S S R
Sbjct: 1303 GSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSR 1362
Query: 888 SYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRS--- 944
S + S S + S +S + S S C+Q S
Sbjct: 1363 GRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSG 1422
Query: 945 RSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSG 1004
S S+ + SRS SR S S ++S + + S S +SPS G
Sbjct: 1423 HSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG 1482
Query: 1005 SRKRSWGHESPEERHSGRRDFIRSK-IYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGP 1063
G S + + S+ Y S S H G E + G G ++G
Sbjct: 1483 RHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGH 1542
Query: 1064 PSQNSNIGTGRGSEGDCSPEDKNS 1087
S + G+ G C +S
Sbjct: 1543 SSTHGQHGSTSGQSSSCGQHGASS 1566
Score = 74.7 bits (182), Expect = 6e-13
Identities = 133/566 (23%), Positives = 178/566 (31%), Gaps = 101/566 (17%)
Query: 596 GSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSET 655
G SS G G + S G S G ++ + S SG + G H S
Sbjct: 1840 GHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS--SGYTQHGSGSGHSSSY 1897
Query: 656 EDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRK 715
E G RSG+S R ++ SS +H + + + + G S +
Sbjct: 1898 EQHG-------SRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPS 1950
Query: 716 RKKNKSSAPADSERGPKPEPPGSGSPAPP-------------RRRRRAQDDS-------- 754
R ++ S + S GP G S P R R Q
Sbjct: 1951 RGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSS 2010
Query: 755 -------QRRSLP----------AEEGSSGKKDEGGGGSSSQDHGGRKHKGE-LPPSSCQ 796
Q S A G S + G GSS GR+ G P Q
Sbjct: 2011 GHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ 2070
Query: 797 RRAGTKR----------SSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSG 846
R +G+++ S RSS Q G +S H S YS+
Sbjct: 2071 RGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 2130
Query: 847 SEHSRSRSRSGR-----RHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRS 901
S + + SRSG+ RH S S Y S S + RQ S S S S R
Sbjct: 2131 SGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPS----RG 2186
Query: 902 RRHSKRSHDSDDSDYASSKHRSK----------------RHK--------YSSSDDDYSL 937
R S H S + S RS +H+ YS
Sbjct: 2187 RHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGH 2246
Query: 938 SCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRS---RSYSRDRSR 994
CSQ + S S G S S S + S ++++ Q S +S SR R
Sbjct: 2247 FCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHG 2306
Query: 995 STRSPSQRSGSRKRSWGHESPEERH---SGRRD-FIRSKIYRSQSPHYFRSGRGEGPGKK 1050
S S G G S RH SG+ F + QS Y + G G G
Sbjct: 2307 SGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSS 2366
Query: 1051 DDGRGDDSKATGPPSQNSNIGTGRGS 1076
+ G S G S+ G+ GS
Sbjct: 2367 YEQHGSRS---GQSSRGERHGSSSGS 2389
Score = 71.2 bits (173), Expect = 7e-12
Identities = 120/517 (23%), Positives = 162/517 (31%), Gaps = 68/517 (13%)
Query: 596 GSSSKDHLQGLDPGEPNK-------SKEVGGEKIVRSSGGRMDAPASGSACSGLNKQE-- 646
G SS+ G G + S++ G S G+ +P+ G SG +
Sbjct: 1435 GQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY 1494
Query: 647 -PGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKK------HKKSSKHKRKHKADTEEKS 699
P GS + G SG HR + + H SS H H
Sbjct: 1495 SPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSG 1554
Query: 700 SKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSL 759
+ G+ +S+ S G GSGS R+ Q
Sbjct: 1555 QSSSCGQHG------------ASSGQSSSHGQH----GSGSSQSSGYGRQGSGSGQ---- 1594
Query: 760 PAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDED 819
S G G G S +G SS Q +G SS H S
Sbjct: 1595 -----SPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSS 1649
Query: 820 SDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRS-SRRSYSSSSDASS 878
S H Q+ + G H S SRS R+ H S SR+S S
Sbjct: 1650 YSQHGSGSGHSSGYGQHGSRSGQSSRGERHG-SSSRSSSRYGQHGSGSRQSSGHGRQGSG 1708
Query: 879 DQSCYSRQRSYS----DDSYSDYSDRSRRHSKRSHDSDDSDYAS--------SKHRSKRH 926
SR R S S+ + S R S R S ++S S H S
Sbjct: 1709 SGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYS 1768
Query: 927 KYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRS- 985
++ S + CSQ + S S G S S S + S ++++ Q S
Sbjct: 1769 QHGSGSGHF---CSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSG 1825
Query: 986 --RSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERH---SGRRD-FIRSKIYRSQSPHYF 1039
+S SR R S S G G S RH SG+ F + QS Y
Sbjct: 1826 SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYT 1885
Query: 1040 RSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGS 1076
+ G G G + G S G S+ G+ GS
Sbjct: 1886 QHGSGSGHSSSYEQHGSRS---GQSSRGEQHGSSSGS 1919
Score = 68.6 bits (166), Expect = 4e-11
Identities = 123/532 (23%), Positives = 177/532 (33%), Gaps = 41/532 (7%)
Query: 690 KHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRR 749
K + DT + + E EK ++ K+++ + SS A GS P RR
Sbjct: 100 KLRDDTHQHQEEQEETEK-EENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRR 158
Query: 750 AQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDH--GGRKHKGELPPSSCQRRAGTKRSSRS 807
S +R + S + G +S H GR G S S +S
Sbjct: 159 L---SFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQS 215
Query: 808 SHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSR 867
S SG S S H+ S YS+ SGS HS + G R
Sbjct: 216 SSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQH----GSGSGHSSGYGQHGSRSGQSSRGE 271
Query: 868 RSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHK 927
R SSS +SS Y + S S S S SH + S S H
Sbjct: 272 RHRSSSGSSSS----YGQHGSGSRQSLGHGRQGSGSRQSPSHVR----HGSGSGHSSSHG 323
Query: 928 YSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRS 987
S YS S S S + G +SS S+ S + HS + +
Sbjct: 324 QHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSG------SGHSSSQGQH 377
Query: 988 YSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGP 1047
S S+ S + S+G RHS R S +S SG G+ P
Sbjct: 378 GSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSP 437
Query: 1048 GKKDDGRG-DDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVER-- 1104
G G S ++GP S +G G + S E + T S +
Sbjct: 438 SSGQHGTGFGRSSSSGPYVSGSGYSSGFGHH-ESSSEHSSGYTQHGSGSGHSSGHGQHGS 496
Query: 1105 KPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLGNKPVLPLIGKLPATRKPNKKCEES 1164
+ S + + AG G G SLG+ G+ P+ P++ ES
Sbjct: 497 RSGQSSRGERQGSSAG---SSSSYGQHGSGSRQSLGHSRHGSGSGQSPS---PSRGRHES 550
Query: 1165 GLERGEEQEQSETEEGPPGSSDALFGHQFPSEETTGPLLDPPPEESKSGEAT 1216
G + + GP G + P E +G +ES+SG+++
Sbjct: 551 G-------SRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSS 595
Score = 64.7 bits (156), Expect = 6e-10
Identities = 93/405 (22%), Positives = 138/405 (34%), Gaps = 44/405 (10%)
Query: 672 SHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGP 731
+H+H+++++ + ++KR+ + + S E+ S+ + + +S + S +
Sbjct: 105 THQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRD 164
Query: 732 KPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELP 791
S S + D Q SSG+ G G S ++G
Sbjct: 165 FSGQHNSYSGQSSSYGEQNSDSHQ---------SSGRGQCGSGSGQSPNYG--------- 206
Query: 792 PSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSR 851
Q +G S +SS SG S S H KS S S + SGS HS
Sbjct: 207 ----QHGSG---SGQSSSNDTHGSGSGQSSGFSQH----KSSSGQSSGYSQHGSGSGHSS 255
Query: 852 SRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDS 911
+ G R R SSS +SS Y + S S S S SH
Sbjct: 256 GYGQHGSRSGQSSRGERHRSSSGSSSS----YGQHGSGSRQSLGHGRQGSGSRQSPSH-- 309
Query: 912 DDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSK 971
+ S S H S YS S S S + G +SS S
Sbjct: 310 --VRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYS----- 362
Query: 972 RRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIY 1031
+ S + HS + + S S+ S + S+G RHS R S
Sbjct: 363 -KHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSG 421
Query: 1032 RSQSPHYFRSGRGEGPGKKDDGRG-DDSKATGPPSQNSNIGTGRG 1075
+S SG G+ P G G S ++GP S +G G
Sbjct: 422 QSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFG 466
Score = 56.2 bits (134), Expect = 2e-07
Identities = 73/279 (26%), Positives = 107/279 (38%), Gaps = 24/279 (8%)
Query: 815 SGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSS 874
SG + DD H+ Q+ +E+EE + S S S +G S R+ R S +
Sbjct: 97 SGSKLRDDTHQHQEEQEE----TEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGT 152
Query: 875 DASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASS---------KHRSKR 925
++ S + + R S +SYS S + SH S S +H S
Sbjct: 153 ESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGS 212
Query: 926 HKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRS---KRRSRSTTAHSW 982
+ SSS+D + QS S+ H +S G S+ S S S + SRS +
Sbjct: 213 GQ-SSSNDTHGSGSGQSSGFSQ-HKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRG 270
Query: 983 QRSRSYSRDRS----RSTRSPSQRSGSRKRSWGHESPEE-RH-SGRRDFIRSKIYRSQSP 1036
+R RS S S + S R+ S +SP RH SG + S S
Sbjct: 271 ERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSS 330
Query: 1037 HYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRG 1075
+ + G E + G G +G S S G+G G
Sbjct: 331 YSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSG 369
Score = 53.5 bits (127), Expect = 1e-06
Identities = 81/348 (23%), Positives = 115/348 (33%), Gaps = 31/348 (8%)
Query: 596 GSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRM-----DAPASGSACSGLNKQEPGGS 650
G SS G G+ + + G S GR +P G SG + G
Sbjct: 2494 GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 2553
Query: 651 HGSETEDTGRSLPSKKERSG--KSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKS 708
HGS +GRS S + SG +S + S +H + + S + G +S
Sbjct: 2554 HGS---GSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS 2610
Query: 709 KKRKKRKRKKNKSSAPAD-------SERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPA 761
+ + +R + S + + S + GSGS P R R S
Sbjct: 2611 GQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQ 2670
Query: 762 EEGSSGKKDEGGGGSSSQDHGG--RKHKGELPPSSCQRRAGT------KRSSRSSHRSQP 813
SG+ G S H +H+ SS + G+ + S Q
Sbjct: 2671 HGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQS 2730
Query: 814 SSGDED--SDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYS 871
S+ D++ S SS H+ S S S +GS S S RH S SY
Sbjct: 2731 STFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHG----RHGSGSGQSSSYG 2786
Query: 872 SSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASS 919
S S YS+ S S Y H S S + SS
Sbjct: 2787 QHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGSYFLSFPSS 2834
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 90.5 bits (223), Expect = 1e-17
Identities = 163/736 (22%), Positives = 251/736 (34%), Gaps = 114/736 (15%)
Query: 645 QEPGGSHGSETEDTGR-----SLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKS 699
+EP + T D + +P KE S + + K+K+K K + + + K+ + +S
Sbjct: 231 KEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRS 290
Query: 700 SKAESGEKSKKRKKRKRKKNKSSAPADSER-GPKPEPPGSGSPAPPRRRR-RAQDDSQRR 757
++ + R R + P+ R P+ P P PPR RR R+ +RR
Sbjct: 291 RSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRR 350
Query: 758 SLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGD 817
S + GSS SSS R PP +R T R + R PS+
Sbjct: 351 SSASLSGSS---------SSSSSSRSRS-----PPKKPPKR--TSSPPRKTRRLSPSA-- 392
Query: 818 EDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDAS 877
+ R H+ SP + + HS + +S R S S S +S
Sbjct: 393 -----SPPRRRHRPSPPATPPPK------TRHSPTPQQSNRTRKSRVSV--SPGRTSGKV 439
Query: 878 SDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSL 937
+ ++ S S + S + +D + + +R SS D S
Sbjct: 440 TKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSS 499
Query: 938 SCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTR 997
S S+ RSH + R R S S S S S R+ + T+ +R RS S +R R
Sbjct: 500 SSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRR 559
Query: 998 SPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDD 1057
SPS R+R P R RS R SP R P K+
Sbjct: 560 SPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKR------- 612
Query: 1058 SKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPN 1117
A+ PP SP K R+V P +
Sbjct: 613 RTASPPPPPKRRASP--------SPPPK--------------RRVSHSPPPKQRSSPVTK 650
Query: 1118 KAGPKLKDPPQGYFGPKLPPSLGNKPVLPLIGKLPATRKPNKKCEESGLERGEEQEQSET 1177
+ P L + P P +PNK+ S R +T
Sbjct: 651 RRSPSLSSKHRKGSSPSRSTREARSP------------QPNKRHSPSPRPRA-----PQT 693
Query: 1178 EEGPP----GSSDALFGHQFPSEETTGPL--LDPPPEESKSGEATADHPVAPLGTPAHSD 1231
PP G+S + Q PS +T P+ + PE K +A + P + + + S
Sbjct: 694 SSSPPPVRRGASSSPQRRQSPS-PSTRPIRRVSRTPEPKKIKKAASPSPQS-VRRVSSSR 751
Query: 1232 CYPGDPTISHNYLPDPSDGDTLESLDSSSQPGPVESSLLPIAPDLEHFPSYAPPSGDPSI 1291
G P + P P S S P S +P+ PS +PP S
Sbjct: 752 SVSGSPEPAAKKPPAP------PSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRN--SD 803
Query: 1292 ESTDGAEDASLAPLESQPITFTPEEMEKYSKLQQAAQQHIQQQLLAKQVKAFPASAALAP 1351
+ G + ++ K K + ++H +++ +A A AA+A
Sbjct: 804 QEGGGKKKKK-----------KKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAA 852
Query: 1352 ATPAL---QPIHIQQP 1364
AT L +P+ +P
Sbjct: 853 ATTTLAQEEPVAAPEP 868
Score = 77.8 bits (190), Expect = 7e-14
Identities = 158/729 (21%), Positives = 253/729 (34%), Gaps = 105/729 (14%)
Query: 666 KERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPA 725
K+ K + +++K + + K K D EEK S E E+S+ ++RK +
Sbjct: 127 KKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSR-------- 178
Query: 726 DSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRK 785
P P SP R R+R+ S R + S + ++
Sbjct: 179 ------SPSPRRRSSPV-RRERKRSHSRSPRHRTKSRSPSPAPEK-------------KE 218
Query: 786 HKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDS 845
ELP S + + + + + S+ E + + SP + S++E+E++
Sbjct: 219 KTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPK-----EPSPEKNSKKEKEKEK 273
Query: 846 ----GSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRS 901
S+SRSR+ R SH RR + S S + S + S +R S R
Sbjct: 274 TRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRR--------PSPRR 325
Query: 902 RRHSKRSHDSDDSDYASSKHRSKRHKYSS-SDDDYSLSCSQSRSRSRSHTRERSRSRGRS 960
R +R + S R +R +S S S S S+SRS + + S ++
Sbjct: 326 RTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKT 385
Query: 961 RSSSCSRSRSKRRSRST--------TAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWG- 1011
R S S S +RR R + T HS +S +SR + SP + SG + G
Sbjct: 386 RRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGT 445
Query: 1012 --HESPEERHSGRRDFIR-------SKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATG 1062
ESP R+ + K+ + S R R + D G S +
Sbjct: 446 EKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDS-GSSSSSED 504
Query: 1063 PPSQNSNIGTGR-GSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGP 1121
+ S++ G G SP S + + ++ R R+ S T + P
Sbjct: 505 ERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRR---SPSPPPTRRRRSP 561
Query: 1122 KLKDPPQGYFGPKLPPSLGNKPVLPLIGKLPATRKPNKKCEESGLERGEEQEQSETEEGP 1181
PP+ P PP P P P R P+ + R Q P
Sbjct: 562 SPAPPPRRRRTP-TPPPRRRTPSPP-----PRRRSPSPR-------RYSPPIQRRYSPSP 608
Query: 1182 PGSSDALFGHQFPSEETTGPLLDPPPEESKSGEATADHPVAPLGTPAHSDCYP----GDP 1237
P P T P PPP + ++ + P P P
Sbjct: 609 P-----------PKRRTASP---PPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSP 654
Query: 1238 TISHNYLPDPSDGDTLESLDSSSQPGPVESSLLPIAPDLEHFPSYAPPSGDPSIESTDGA 1297
++S + S + S S P AP P PP + S
Sbjct: 655 SLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSP---PPVRRGASSSPQRR 711
Query: 1298 EDASLAPLESQPITFTPEEMEKYSKLQQAAQQHIQQQLLAKQVKAFPASAALAPATPALQ 1357
+ S + + ++ TPE +K K + Q +++ ++ V P AA P P
Sbjct: 712 QSPSPSTRPIRRVSRTPEP-KKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPP-S 769
Query: 1358 PIHIQQPAT 1366
P+ Q P+T
Sbjct: 770 PVQSQSPST 778
Score = 75.9 bits (185), Expect = 3e-13
Identities = 147/745 (19%), Positives = 257/745 (34%), Gaps = 77/745 (10%)
Query: 336 EKSSDQGLQKVGDSDGSSNLDGKKEDEDPQDGGSLASTLSKLKRMKREEGAGATEPEYYH 395
E ++ Q+ + + +++ + ED+D +D S+ K +R + + P
Sbjct: 125 ELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRR 184
Query: 396 YIPPAHCKVKPNFPFLLFMRASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAE 455
P + K + + + P APE K+ + P+ +K E
Sbjct: 185 RSSPVRRERKRS-------HSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
Query: 456 KT-VSEVSEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSK 514
T S++ + PK + EP EP + +KK E +K S S
Sbjct: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKK-----------EKEKEKTRPRSRSRSKSRS 286
Query: 515 ETSLATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYF 574
T +P+ + + + + P + + + PS + P P +
Sbjct: 287 RTRSRSPSHTRPRRRHRSRSRSYSP---RRRPSPRRRPSP----RRRTPPRRMPPPPRH- 338
Query: 575 DFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPA 634
+ SR+ R + + SSS + P + + + R P
Sbjct: 339 --RRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPR 396
Query: 635 SGSACSGLNKQEPGGSHGSETEDTGRSLPSK-----KERSGKSHRHKKKKKHKKSSKHKR 689
S P H + + R+ S+ SGK +HK +K + S +
Sbjct: 397 RRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPK 456
Query: 690 KHKAD----TEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPR 745
K + E+K K + + ++R++ +R+ +SS+ + S + E P
Sbjct: 457 PRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRS------ 510
Query: 746 RRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSS 805
+ + +RR P+ S + GR+ + PP + +RR +
Sbjct: 511 HVKNGEVGRRRRHSPSRSASPSPRKR----QKETSPRGRRRRSPSPPPT-RRRRSPSPAP 565
Query: 806 RSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRS-----GRRH 860
R P+ + R SP +YS + S S + R+ S RR
Sbjct: 566 PPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRA 625
Query: 861 SSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSK 920
S +R S S S +++RS S S +H K S S + A S
Sbjct: 626 SPSPPPKRRVSHSPPPKQRSSPVTKRRSPS---------LSSKHRKGSSPSRSTREARSP 676
Query: 921 HRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAH 980
+KRH S Q+ S R S S R +S S S +R SR+
Sbjct: 677 QPNKRHSPSPRP-----RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPK 731
Query: 981 SWQRSRSYSRDRSRSTRSPSQRSGS----RKRSWGHESPEERHSGRRDF-----IRSKIY 1031
+++ S S R S SGS K+ SP + S ++ ++
Sbjct: 732 KIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKS 791
Query: 1032 RSQSPHYFRSGRGEGPGKKDDGRGD 1056
+ SP R+ EG GKK + D
Sbjct: 792 PTPSPSPPRNSDQEGGGKKKKKKKD 816
Score = 68.9 bits (167), Expect = 3e-11
Identities = 136/616 (22%), Positives = 212/616 (34%), Gaps = 108/616 (17%)
Query: 610 EPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETED-TGRSLPSKKER 668
E N KE EK S R + S + + P H S + + R PS + R
Sbjct: 262 EKNSKKEKEKEKTRPRSRSRSKS-RSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRR 320
Query: 669 SGKSHRHKKKK-----KHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSA 723
R ++ +H++S R+ + + S + S S+ R K+ ++S+
Sbjct: 321 PSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSS 380
Query: 724 PADSERGPKPEPPGSGSPAPPRRRRR----AQDDSQRRSLPAEEGSSGKKDEGGGGSSSQ 779
P R P S +PPRRR R A + R P + S+ + S +
Sbjct: 381 PPRKTRRLSP------SASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGR 434
Query: 780 DHGG-RKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSE 838
G KHKG + R PS + P +
Sbjct: 435 TSGKVTKHKG------------------TEKRESPSPAPK--------------PRKVEL 462
Query: 839 EEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYS 898
E EED G + + + S RR ++ + S S S +SS+ R + +
Sbjct: 463 SESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGE-----V 517
Query: 899 DRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRG 958
R RRHS ++S KR K +S S S +R R R
Sbjct: 518 GRRRRHS--------PSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRR 569
Query: 959 RSRSSSCSRSRS-----KRRSRSTTAHSWQRSRSYS-----RDRSRSTRSPSQRSGS--- 1005
R + R R+ +RRS S +S R YS + R+ S P +R S
Sbjct: 570 RRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSP 629
Query: 1006 -RKRSWGHESPEERHSG-----RRDFIRSKIYRSQSP-HYFRSGRGEGPGKKDDGRGDDS 1058
KR H P ++ S R + SK + SP R R P K+
Sbjct: 630 PPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKR---HSPSP 686
Query: 1059 KATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVE--------------- 1103
+ P + +S RG+ SP+ + S + + SR E
Sbjct: 687 RPRAPQTSSSPPPVRRGASS--SPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSV 744
Query: 1104 RKPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLGNKPVLPL---IGKLPATRKPNKK 1160
R+ S S V +P A K PP PS P +P+ P+ P
Sbjct: 745 RRVSSSRSVSGSPEPAAKKPPAPPSPV--QSQSPSTNWSPAVPVKKAKSPTPSPSPPRNS 802
Query: 1161 CEESGLERGEEQEQSE 1176
+E G ++ ++++ +
Sbjct: 803 DQEGGGKKKKKKKDKK 818
Score = 43.9 bits (102), Expect = 0.001
Identities = 81/397 (20%), Positives = 128/397 (32%), Gaps = 17/397 (4%)
Query: 309 PVKLESIASVFKDHAEEGTSEDGTKPDEKSSDQGLQKVGDSDGSSNLDGKKEDEDPQDGG 368
P K+E ++ +D + + D + + Q Q DS SS+ EDE P+
Sbjct: 457 PRKVE-LSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSS----SEDERPKRSH 511
Query: 369 SLASTLSKLKRMKREEGAGATEPEYYHYIPP-AHCKVKPNFPFLLFMRASEQMDGDNTTH 427
+ + +R A + + P + P+ P R+
Sbjct: 512 VKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRR 571
Query: 428 PKNAPESKKGSSPKPK--SCIKAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKKA 485
P ++ SP P+ S S ++ S S PK + + P P +A
Sbjct: 572 TPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSP-SPPPKRRTASPPPPPKRRASPSPP 630
Query: 486 LGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTGPFFPVLSKDE 545
VS + S SSK ++P+ + P P
Sbjct: 631 PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA 690
Query: 546 STALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQG 605
P + + P S +P S R T +PK I ++ Q
Sbjct: 691 PQTSSSPPPVRRGASSSPQRRQSPSP-------STRPIRRVSRTPEPKKIKKAASPSPQS 743
Query: 606 LDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSK 665
+ ++S E + S S + + P S T S
Sbjct: 744 VRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSD 803
Query: 666 KERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKA 702
+E GK + KK KKHKK KHK KHK +EK+ A
Sbjct: 804 QEGGGKKKKKKKDKKHKKDKKHK-KHKKHKKEKAVAA 839
Score = 38.9 bits (89), Expect = 0.038
Identities = 51/261 (19%), Positives = 99/261 (37%), Gaps = 25/261 (9%)
Query: 632 APASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKH 691
+P + L+ + GS S + RS P +R S R + + +R
Sbjct: 646 SPVTKRRSPSLSSKHRKGSSPSRSTREARS-PQPNKRHSPSPRPRAPQTSSSPPPVRRGA 704
Query: 692 KADTEEKSSKAESGEK----SKKRKKRKRKKNKSSAPADSER-------GPKPEPPGSGS 740
+ + + S + S S+ + +K KK S +P R PEP
Sbjct: 705 SSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKP 764
Query: 741 PAPPRR-RRRAQDDSQRRSLPAEEGSSG--------KKDEGGGGSSSQDHGGRKHKGELP 791
PAPP + ++ + ++P ++ S D+ GGG + +KHK +
Sbjct: 765 PAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKK 824
Query: 792 PSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSR 851
++ K + ++ + + + A++ L Q+ P E ++E +S +E +
Sbjct: 825 HKKHKKHKKEKAVAAAAAAAVTPA----AIAAATTTLAQEEPVAAPEPKKETESEAEDNL 880
Query: 852 SRSRSGRRHSSHRSSRRSYSS 872
R + RS R++ S
Sbjct: 881 DDLEKHLREKALRSMRKAQVS 901
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 90.1 bits (222), Expect = 1e-17
Identities = 77/386 (19%), Positives = 143/386 (37%), Gaps = 27/386 (6%)
Query: 657 DTGRSLPSKKE---RSGKSHRHKK-----KKKHKKSSKHKRKHKADTEEKSSKAESGEKS 708
D R P +E R G HK ++++++ + +R+ K TE E
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTER--------ETD 76
Query: 709 KKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGK 768
+KR++R+ K ER E R R+R ++ ++++ E
Sbjct: 77 RKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERE-----T 131
Query: 769 KDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRL 828
+ EG G Q G R+ + + + R + R + R++ + + +
Sbjct: 132 EREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRER 191
Query: 829 HQKSPSQYSEEEEEEDSGSEHSRSR-----SRSGRRHSSHRSSRRSYSSSSDASSDQSCY 883
++ + E+ + G E R R + R+ R +R + +++
Sbjct: 192 ERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERA 251
Query: 884 SRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSR 943
S + + D DR R +R + + + R++R + + + + R
Sbjct: 252 SERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER 311
Query: 944 SRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRS 1003
R+R RER R R R R R R K R R + + R +R R R ++R
Sbjct: 312 ERNRKRERERERERERERQRETERDREKERERKRKRQT-EMDRERNRQTGREGRRQAERE 370
Query: 1004 GSRKRSWGHESPEERHSGRRDFIRSK 1029
R+R +S ER RD R +
Sbjct: 371 RERERERDRQSAREREERERDRDRDR 396
Score = 80.9 bits (198), Expect = 9e-15
Identities = 90/480 (18%), Positives = 177/480 (36%), Gaps = 44/480 (9%)
Query: 652 GSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKR 711
GS+ R L + + R + ++K ++ + KR+ + +T+ K + EK + R
Sbjct: 32 GSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRR--EKDRHR 89
Query: 712 KKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDE 771
K+ + ++ + + ER E R R+R ++ ++++ E G++
Sbjct: 90 KRDRHRERQRDREKERERQTDRE----------RDRQREKERNRQKERERETEREGER-- 137
Query: 772 GGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQK 831
G Q G R+ + + + R + R + R++ + + + + ++
Sbjct: 138 ---GRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKN----RQERRE 190
Query: 832 SPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSD 891
Q +E + ED SE R R R R + + R+ + ++ R++
Sbjct: 191 RERQREKENKTEDRHSERGRERERE--RETETETERKRQTDRERDRQRKTEREREKQAER 248
Query: 892 DSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTR 951
+ S+ + +R D D + R +R K D R R R
Sbjct: 249 ERASERETERDKERERERDRD-------RDRDRRQKERERQTDRKRQRRTERDRETERKR 301
Query: 952 ERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWG 1011
ER R R R R + R R + R R +R R RDR + +R RKR
Sbjct: 302 ERQRERERERERNRKRERERERERER-----ERQRETERDREK------ERERKRKRQTE 350
Query: 1012 HESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIG 1071
+ R +GR +++ R + R E ++ D D K ++ G
Sbjct: 351 MDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDG 410
Query: 1072 ---TGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKDPPQ 1128
T + E + E + EK + R+ +R+ + ++ + PP+
Sbjct: 411 QRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPR 470
Score = 72.8 bits (177), Expect = 2e-12
Identities = 74/406 (18%), Positives = 154/406 (37%), Gaps = 31/406 (7%)
Query: 643 NKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKA 702
N+Q+ + GR + +R + R +K++ +++ + +++ +K +
Sbjct: 122 NRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERER 181
Query: 703 ESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAE 762
E + ++ ++R+R+K + SERG + E R+R+ ++ ++R E
Sbjct: 182 EKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERE 241
Query: 763 EGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDD 822
+++ + +D ++ + E + R +R ++ + Q + + +
Sbjct: 242 REKQAERERASERETERD---KERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETE 298
Query: 823 ASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRR-HSSHRSSRRSYSSSSDASSDQS 881
R ++ + + E + E R R R R R +R + D ++
Sbjct: 299 RKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQ 358
Query: 882 CYSRQRSYSDDSYSDYSDRSRRHSKRSHDSD-DSDYASSKHRSKRHKYSSSDDDYSLSCS 940
R ++ +R R+ ++ + + D D K R ++ + D D
Sbjct: 359 TGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQ---TEKDRDGQRETE 415
Query: 941 QSRSRSRSHT----RERSRS------RGRSRSSSCSRSRSKRRSRST----TAHSWQRSR 986
+ R R + RER R R R R R ++R RST RS
Sbjct: 416 KQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSG 475
Query: 987 SYSRDRSRSTR------SPSQ-RSGSRKRSWGH--ESPEERHSGRR 1023
D +R TR SP ++ S + WG ++ R +GRR
Sbjct: 476 VVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRR 521
Score = 48.9 bits (115), Expect = 4e-05
Identities = 48/200 (24%), Positives = 71/200 (35%), Gaps = 19/200 (9%)
Query: 852 SRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDS 911
SR R G + S R R + DA D +RQ+ +R RR KR +
Sbjct: 27 SRRRPGSQESPRR--RGLGQAHKDADGDDRERNRQK-----------ERERRREKRQTER 73
Query: 912 DDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSK 971
+ + RH+ + + R R R+R R + R+R R +
Sbjct: 74 ETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETER 133
Query: 972 R----RSRSTTA-HSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGR-RDF 1025
R R T +R R ++R R T QR R R E + R R R+
Sbjct: 134 EGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERER 193
Query: 1026 IRSKIYRSQSPHYFRSGRGE 1045
R K +++ H R E
Sbjct: 194 QREKENKTEDRHSERGRERE 213
Score = 34.3 bits (77), Expect = 0.93
Identities = 32/115 (27%), Positives = 45/115 (39%), Gaps = 8/115 (6%)
Query: 944 SRSRSHTRERSRSRGRSRS------SSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTR 997
SR R ++E R RG ++ R+R K R R +R R+R R
Sbjct: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKD 86
Query: 998 SPSQRSGSRKRSWGHESPEERHSGR-RDFIRSKIYRSQSPHYFRSGRGEGPGKKD 1051
+R R+R E ER + R RD R K R++ R EG +D
Sbjct: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREK-ERNRQKERERETEREGERGRD 140
Score = 32.7 bits (73), Expect = 2.7
Identities = 25/114 (21%), Positives = 52/114 (45%), Gaps = 15/114 (13%)
Query: 92 EDATERRRVLEVEKEDTEELRQKYKDYVDKEKAIAKALEDLRANFYCELCDKQYQKHQEF 151
E TER+R + E++ + ++ + ++E+A + E DK+ ++ ++
Sbjct: 219 ETETERKRQTDRERDRQRKTEREREKQAERERASERETER----------DKERERERDR 268
Query: 152 DNHINSYDHAHKQRLKDLKQREFARNVSSRSRKDEKKQEKALRRLHELAEQRKQ 205
D D K+R + ++ R + R R+ E+K+E+ R E RK+
Sbjct: 269 D---RDRDRRQKERERQTDRKRQRR--TERDRETERKRERQRERERERERNRKR 317
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 90.1 bits (222), Expect = 1e-17
Identities = 110/413 (26%), Positives = 156/413 (37%), Gaps = 63/413 (15%)
Query: 644 KQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHK-----KSSKHKRKHKADTEEK 698
+++P S GS++ S S H +++KHK K SK +RK + +EE
Sbjct: 189 RKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEP 248
Query: 699 SSK--------AESGEKSKKRKKRKRKKNKSSAPADSERGPKPE---------PPGSGSP 741
+K +E + ++KR K + E P PE P + P
Sbjct: 249 RNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPVVTAEP 308
Query: 742 APPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGG--------SSSQDHGGRKHKGELPPS 793
P Q+ S+ SG+K +G G S S E PP
Sbjct: 309 EPKIPDVAPIVSDQKPSV----SKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPPH 364
Query: 794 SCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSH----RLHQKSPS-----QYSEEEEEED 844
+ R+ R + S GD+ SD SS L Q+S S YS+
Sbjct: 365 -WKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARH 423
Query: 845 SGSEHSRSRSRSG------------RRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDD 892
SG R + + RRH ++ +R SD S +S R +S D
Sbjct: 424 SGHHKKRRKEKKVKHKKKGKKQKHCRRHK--QTKKRRILIPSDIESSKSSTRRMKSSCDR 481
Query: 893 SYSDYSDRSRRH--SKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHT 950
S S H SKR D D SS S R Y S S S SRSR+ S +
Sbjct: 482 ERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKS 541
Query: 951 RERSRSRGRSRSSSCSRSRSKRRSRS--TTAHSWQRSRSYSRDRSRSTRSPSQ 1001
SRSR +SRSSS S R KR S+S TA ++ + R+T + ++
Sbjct: 542 SSHSRSRSKSRSSSKSGHR-KRASKSPRKTASQLSENKPVKTEPLRATMAQNE 593
Score = 84.3 bits (207), Expect = 8e-16
Identities = 132/515 (25%), Positives = 187/515 (36%), Gaps = 93/515 (18%)
Query: 674 RHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKP 733
+ +KK H + S + +E S E+S++RK ++R K K S E
Sbjct: 187 KKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSE 246
Query: 734 EP-------PGSGSPAPPRRRRRAQDDSQRRSLPA---EE-------------------- 763
EP P S +R+ D S +R P EE
Sbjct: 247 EPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPVVTA 306
Query: 764 --------------------GSSGKKDEGGG--------GSSSQDHGGRKHKGELPPSSC 795
SG+K +G G S S E PP
Sbjct: 307 EPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPP-HW 365
Query: 796 QRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSR 855
+ R+ R + S GD+ SD SS R ++S SQ S S S +
Sbjct: 366 KEEMQRLRAYRPPSGEKWSKGDKLSDPCSS-RWDERSLSQRSR------SWSYNGYYSDL 418
Query: 856 SGRRHSSHRSSRR---SYSSSSDASSDQSC----YSRQRSYSDDSYSDYSDRSRRHSKRS 908
S RHS H RR + C +++R S + S S R K S
Sbjct: 419 STARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSS 478
Query: 909 HDSDDSDYAS--SKHRSKRHKYSSSDDDYSLSCS-------QSRSRSRSHTRERSRSRGR 959
D + S +S S H S + +S SD D S + +S+S S+S++R SRSR
Sbjct: 479 CDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTA 538
Query: 960 SRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSR-STRSPSQRSGSRKRSWGHESPEER 1018
S+SSS SRSRSK RS S + H + S+S + S+ S P + R +E+ +
Sbjct: 539 SKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQ 598
Query: 1019 HSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGP---PSQN----SNIG 1071
+ I S SP R G+ P K R + KA P Q+ +NI
Sbjct: 599 PVVAENI--PVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANI- 655
Query: 1072 TGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKP 1106
GS +KNS + + K R E P
Sbjct: 656 KETGSSSSYHKREKNSESDQSTYSKYSDRSSESSP 690
Score = 82.4 bits (202), Expect = 3e-15
Identities = 168/771 (21%), Positives = 284/771 (36%), Gaps = 146/771 (18%)
Query: 429 KNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKKALGG 488
+ P +GS S +++S+ + ++ E + P SK K+A
Sbjct: 189 RKKPTHSEGSDSSSNS---SSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSS 245
Query: 489 DVSDQ----SLESHSQK--VSETQMCESNSSKETSLATPAGKESQEGPKHPTGPFF---- 538
+ + + HS++ +E + +S++ +E + P +E P P F
Sbjct: 246 EEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRP-----EEIPPVPENRFLLRRD 300
Query: 539 -PVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGS 597
PV++ + + P I + +PS+S S + + + R++ + D S
Sbjct: 301 MPVVTAEPEPKI--PDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDS 358
Query: 598 SS-----KDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGS----ACSGLNKQEPG 648
S K+ +Q L P GEK S G ++ P S + S ++
Sbjct: 359 SETPPHWKEEMQRLRAYRPPS-----GEKW--SKGDKLSDPCSSRWDERSLSQRSRSWSY 411
Query: 649 GSHGSETEDTGRSLPSKKERSGKSHRHKKK-KKHKKSSKHKRKHK------ADTEEKSSK 701
+ S+ S KK R K +HKKK KK K +HK+ K +D E S
Sbjct: 412 NGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSS 471
Query: 702 AESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRR-RAQDDSQR---- 756
+ S R++ R + SS + K + S R R++ SQ
Sbjct: 472 TRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRG 531
Query: 757 --RSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPS 814
RS A + SS + SSS+ G RK + P + + + K R+ +
Sbjct: 532 SSRSRTASKSSSHSRSRSKSRSSSKS-GHRKRASKSPRKTASQLSENKPVKTEPLRATMA 590
Query: 815 SGDED------SDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRR 868
+ +++ L P + ++ S ++ H S
Sbjct: 591 QNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTY 650
Query: 869 SYSSSSDASSDQSCYSRQRSYSDD--SYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRH 926
S ++ + S S + R+++ D +YS YSDRS S RS SS+ RS
Sbjct: 651 SLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSR------SSRSRS--- 701
Query: 927 KYSSSDDDYSLSCSQSRSRSRSHTRERS-RSRGRSRS-----SSCSRS------------ 968
YS S ++SRS + SH+R RS SR SR+ S CSRS
Sbjct: 702 --------YSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGR 753
Query: 969 RSKRRSRST-----------------TAHS--------------WQRSRS---YSRDRSR 994
R+KRR RS+ T HS + SRS YS D +
Sbjct: 754 RAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQ 813
Query: 995 STRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPH------------YFRSG 1042
S+ +Q + +++ E + R +SK R + PH + R+G
Sbjct: 814 SSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSER-ECPHSKKRTLKENLSDHLRNG 872
Query: 1043 ----RGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVT 1089
R G K D + + S+N + + EG+ + + ++ V+
Sbjct: 873 SKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVS 923
Score = 74.3 bits (181), Expect = 8e-13
Identities = 75/221 (33%), Positives = 104/221 (47%), Gaps = 27/221 (12%)
Query: 800 GTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRR 859
G + +S ++ +P S ++ + RL+++ +Q S +E+ S + S+SRS S R
Sbjct: 1261 GLRIEIKSKNKVRPGSLFDEVRKTA--RLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSR 1318
Query: 860 HSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASS 919
S SR S S YS RS S S S Y RS S+ Y+
Sbjct: 1319 SKSETKSRHRTRSVS--------YSHSRSRSRSSTSSYRSRSYSRSRSR-----GWYSRG 1365
Query: 920 KHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRE-RSRSRGRSRSSSCSRSRSKRRSRSTT 978
+ RS+ Y S Y + SRSRSRS + + SRSR + S SRSRS RS +
Sbjct: 1366 RTRSRSSSYRS----YKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRS----RSRS 1417
Query: 979 --AHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEE 1017
+ S+ R RSY+R RSRS RS S S + H SP E
Sbjct: 1418 QRSDSYHRGRSYNR-RSRSCRSYGSDSESDRSYSHHRSPSE 1457
Score = 68.9 bits (167), Expect = 3e-11
Identities = 70/194 (36%), Positives = 92/194 (47%), Gaps = 39/194 (20%)
Query: 850 SRSRSRSGRRHSSHRSSRR--SYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKR 907
S+++ R G R + R + ++SSD+ SR DDS S RSR S+
Sbjct: 1268 SKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRD----DDSQSRSPSRSRSKSE- 1322
Query: 908 SHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRER---SRSRGRSRSSS 964
S+HR++ YS S S S RSRS S +R R SR R RSRSSS
Sbjct: 1323 ---------TKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSS 1373
Query: 965 -----CSRSRSKRRSRSTTAHSWQRSRSY--------SRDRSRSTRSPSQ---RSGSRK- 1007
R+ S+ RSRS++ RSRSY SR RSRS RS S RS +R+
Sbjct: 1374 YRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRS 1433
Query: 1008 ---RSWGHESPEER 1018
RS+G +S +R
Sbjct: 1434 RSCRSYGSDSESDR 1447
Score = 67.8 bits (164), Expect = 8e-11
Identities = 58/177 (32%), Positives = 85/177 (48%), Gaps = 16/177 (9%)
Query: 921 HRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAH 980
+R R++ SSSD+ S+SRS S +R +S ++ R R+ S S S S+ RSRS+T
Sbjct: 1288 NRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSST-- 1345
Query: 981 SWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIY----RSQS- 1035
S RSRSYSR RSR S R +R RS + S + + R RS Y RS+S
Sbjct: 1346 SSYRSRSYSRSRSRGWYS---RGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSY 1402
Query: 1036 --PHYFRSGRGEGPGKKDD----GRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKN 1086
Y+ R ++ D GR + ++ S S+ + R SP + +
Sbjct: 1403 TYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESS 1459
Score = 64.3 bits (155), Expect = 8e-10
Identities = 89/427 (20%), Positives = 150/427 (35%), Gaps = 65/427 (15%)
Query: 661 SLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNK 720
SL + KE S HK++K + K+ + E S ++ S + R +++
Sbjct: 651 SLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSR 710
Query: 721 SSAPADSERGPKPEPPGSGSPAPPRRRRRAQ--DDSQRRSLPAEEG--------SSGKKD 770
S A + S + P S S + + +Q S S+ +++G SSGKK+
Sbjct: 711 SLASSHS----RSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKN 766
Query: 771 EGGG---GSSSQDHGGRKHKGELPPSSCQRRAGTKRSSR--SSHRSQPS-----SGDEDS 820
SSS+ K+ SSC R+ RSS SS Q S S E
Sbjct: 767 SVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKE 826
Query: 821 DDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSR-------------------SRSGRRHS 861
R H K EE+ + + HS+ R + +G +
Sbjct: 827 KQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWD 886
Query: 862 SHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKH 921
S +S R + +S S S + + DS S+ S+ + + S ++
Sbjct: 887 SESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNG 946
Query: 922 RSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHS 981
K K +S D SCS S + + + S+ + + + K + + H
Sbjct: 947 AWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHK 1006
Query: 982 ---------WQRSRSYSRDRSR--STRSPSQRSGSRKRSWGHE-----------SPEERH 1019
WQ + + + +Q S +K S +E S EE
Sbjct: 1007 APKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEEDL 1066
Query: 1020 SGRRDFI 1026
SG+ D +
Sbjct: 1067 SGKHDTV 1073
Score = 61.6 bits (148), Expect = 5e-09
Identities = 144/665 (21%), Positives = 242/665 (36%), Gaps = 117/665 (17%)
Query: 330 DGTKPDEKSSDQGLQKVGDSDGSSNLDGKKEDEDPQDGGSLASTLSKLKRMKREEGAGAT 389
+G+KP K+ DS+ +S D K ++ S +EEG +
Sbjct: 871 NGSKPKRKNY---AGSKWDSESNSERDVTKNSKNDSHPSS-----------DKEEGEATS 916
Query: 390 EPEYYHYIPPAHCKVKPNFPFLL----------FMRASEQMDGDNTTHPKNAPESKKGSS 439
+ E + H KVKP + + ++ ++ + E+ +G
Sbjct: 917 DSE--SEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKP 974
Query: 440 PKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLESH- 498
K K K + K V E + K+ P + G+ ++ ++
Sbjct: 975 QKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQ 1034
Query: 499 -SQKVSETQMCESNSS-KETSLATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELL 556
+Q+ E ++ E+N + K+ L T E KH T + S+L
Sbjct: 1035 VTQESKEKKVSENNETIKDNILKTEKSSEEDLSGKHDT--------------VTVSSDLD 1080
Query: 557 IFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKE 616
FTK + +S S L TE+ + ++Q ++ PN
Sbjct: 1081 QFTKDDSKLSISPTAL---------------NTEE----NVACLQNIQHVEESVPN---- 1117
Query: 617 VGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHK 676
G E ++++ S+ + + + P G+ +T D L K++ + + + +
Sbjct: 1118 -GVEDVLQTDDNMEICTPDRSSPAKVEETSPLGNARLDTPDINIVL--KQDMATEHPQAE 1174
Query: 677 KKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPP 736
K+ S+ K + ++ SS + + KK +K++ + D + P
Sbjct: 1175 VVKQESSMSESKVLGEVGKQDSSSASLASAGESTGKKEVAEKSQINL-IDKKWKPLQ--- 1230
Query: 737 GSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSC- 795
G G+ A P + + + + E G + E K K ++ P S
Sbjct: 1231 GVGNLAAPNAATSSAVEVKVLTTVPEMKPQGLRIE------------IKSKNKVRPGSLF 1278
Query: 796 ------QRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQ---------YSEEE 840
R R+ SS Q S D+DS S R KS ++ YS
Sbjct: 1279 DEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSR 1338
Query: 841 EEEDSGSEHSRSRSRS----------GR---RHSSHRS--SRRSYSSSSDASSDQSCYSR 885
S + RSRS S GR R SS+RS S R+ S S SS +SR
Sbjct: 1339 SRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSR 1398
Query: 886 QRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSR 945
RSY+ DSY S RSR S+RS + + RS R S S+ D S S +S S
Sbjct: 1399 SRSYTYDSYYSRS-RSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSE 1457
Query: 946 SRSHT 950
S ++
Sbjct: 1458 SSRYS 1462
Score = 43.1 bits (100), Expect = 0.002
Identities = 61/228 (26%), Positives = 82/228 (35%), Gaps = 46/228 (20%)
Query: 922 RSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHS 981
+ K+ +S D S S S S S S S E RSR R RSK+R + ++
Sbjct: 188 KRKKPTHSEGSDSSSNSSSSSESSSESEL-EHERSRRRKHKRRPKVKRSKKRRKEASSSE 246
Query: 982 WQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHES-----------PEERHSGRRDF----- 1025
R++ + S RS + S S E PE R RRD
Sbjct: 247 EPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPVVTA 306
Query: 1026 -------IRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEG 1078
+ I Q P +SGR K GRG T P S++ SE
Sbjct: 307 EPEPKIPDVAPIVSDQKPSVSKSGR------KIKGRGTIRYHTPPRSRSC-------SES 353
Query: 1079 DCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKDP 1126
D +D +S T E++Q + R PS + G KL DP
Sbjct: 354 D---DDDSSETPPHWKEEMQRLRAYRPPSGEKW------SKGDKLSDP 392
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sapiens]
Length = 805
Score = 88.2 bits (217), Expect = 5e-17
Identities = 99/373 (26%), Positives = 156/373 (41%), Gaps = 44/373 (11%)
Query: 786 HKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQK--SPSQYSEE-EEE 842
H ++ Q TK + H+ Q S ++ +A +++K +P++ + E +
Sbjct: 437 HDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPK 496
Query: 843 EDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSR 902
++ + + RSRSG S SS SS+S S S S S S S R +
Sbjct: 497 KEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKK 556
Query: 903 RHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSL---------SCSQSRSRSRSHTRER 953
RHS+ + + + S+ S+R K S+ + S + R R+RS +RER
Sbjct: 557 RHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRER 616
Query: 954 SRSRGRS---RSSSCSRSRSKRRSR--------STTAHSW-----------QRSRSYSRD 991
RSR RS R++ SRSRS+ R + S +H +RSRS +D
Sbjct: 617 RRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKD 676
Query: 992 RSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKD 1051
R + + + RK E + + S + D ++ K R + RSG +
Sbjct: 677 RKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRK--RESERTFSRSGSISVKIIRH 734
Query: 1052 DGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEE 1111
D R D K+T +++S +G S G S E S K K + K R SV E+
Sbjct: 735 DSRQDSKKST---TKDSKKHSGSDSSGRSSSESPGSSKEK----KAKKPKHSRSRSV-EK 786
Query: 1112 VQATPNKAGPKLK 1124
Q + KA K K
Sbjct: 787 SQRSGKKASRKHK 799
Score = 80.1 bits (196), Expect = 1e-14
Identities = 77/332 (23%), Positives = 132/332 (39%), Gaps = 27/332 (8%)
Query: 611 PNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTG--RSLPSKKER 668
PN++ V K + SGS+ SG + S S T + S
Sbjct: 486 PNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT 545
Query: 669 SGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKK--RKRKKNKSSAPAD 726
S +S K+KK+H +S K + S+ E ++ R K +R+ N++S +
Sbjct: 546 SSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERE 605
Query: 727 SERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKK--DEGGGGSSSQDHGGR 784
R + SP+ RRR R++ +R + + S ++ D+ G S H
Sbjct: 606 RRR--------NRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSH--- 654
Query: 785 KHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEED 844
KHKGE +R+ RS + + + + D + ++ ++S +++
Sbjct: 655 KHKGEAKEQ--ERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLK 712
Query: 845 SGSEHSRSRSRSGR------RHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYS 898
E R+ SRSG RH S + S++S + S S R S S S +
Sbjct: 713 RKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKK 772
Query: 899 DRSRRHSKRSHDSDDSDYASSKHRSKRHKYSS 930
+ +HS+ S + S K S++HK S
Sbjct: 773 AKKPKHSRSR--SVEKSQRSGKKASRKHKSKS 802
Score = 73.9 bits (180), Expect = 1e-12
Identities = 136/618 (22%), Positives = 229/618 (37%), Gaps = 111/618 (17%)
Query: 452 QGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKK---ALGGD---VSDQSLESHSQKVSET 505
+G EK E ++ ++ M + SK E K A GGD + +S ++ +T
Sbjct: 238 EGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDT 297
Query: 506 QMCESNSS-KETSLATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTK---A 561
+ E+ SS K T +P +E P E T + ++++ TK
Sbjct: 298 ENVEAASSGKVTRSPSPVPQEEHSDP--------------EMTEEEKEYQMMLLTKMLLT 343
Query: 562 EPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEK 621
E + + +Y+ K DA K T+ P +K++
Sbjct: 344 EILLDVTDEEIYYVAK-----DAHRKATKAP---------------------AKQLAQSS 377
Query: 622 IVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTG--RSLPSKKERSGKSHRHKKKK 679
+ S G GS S +++ GS S+T+D + K+E + + ++
Sbjct: 378 ALASLTGLGGLGGYGSGDSE-DERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLL 436
Query: 680 KHKKSSKHKRKHKADTEEKSSKAESGEKSKKR-----------KKRKRKKNKSSAPADSE 728
K+ + K++ + T+E + + S ++KR N++++ + +
Sbjct: 437 HDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPK 496
Query: 729 RGPKPEPP------GSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHG 782
+ K + GS S R S S + SSG SS +
Sbjct: 497 KEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK- 555
Query: 783 GRKHKGELPPSSCQRRAGTKRSSR----SSHRSQPSSGDEDSDDASS---HRLHQKSPSQ 835
++H P+ RR+ ++ SR S+R++ D + +S R +SPS+
Sbjct: 556 -KRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSR 614
Query: 836 Y---SEEEEEEDSGSEHSRSRSRSGRRHSSHRS--SRRSYSSSSDASSDQSCYSRQRSYS 890
S + + SRSRSR R+ R S S+ +A + R RS
Sbjct: 615 ERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSID 674
Query: 891 DDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDD----------DYSLSCS 940
D +R R KR K K K+SS DD +S S S
Sbjct: 675 KDRKKKDKEREREQDKRKE--------KQKREEKDFKFSSQDDRLKRKRESERTFSRSGS 726
Query: 941 --------QSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDR 992
SR S+ T + S+ S SS S S S S+ A + SRS S ++
Sbjct: 727 ISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEK 786
Query: 993 S-RSTRSPSQRSGSRKRS 1009
S RS + S++ S+ RS
Sbjct: 787 SQRSGKKASRKHKSKSRS 804
Score = 64.3 bits (155), Expect = 8e-10
Identities = 69/321 (21%), Positives = 124/321 (38%), Gaps = 16/321 (4%)
Query: 676 KKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEP 735
K+ K+ +K + + + S+ S S + SS + PK +
Sbjct: 497 KEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKK 556
Query: 736 PGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSC 795
S S +P + RR++ S R + E + K S+ + + P
Sbjct: 557 RHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRER 616
Query: 796 QRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSR 855
+R R R++ S+ S D D L S ++ E +E++ E SRS +
Sbjct: 617 RRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNS-HKHKGEAKEQERKKERSRSIDK 675
Query: 856 SGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSD 915
++ R + D+ ++R D +S DR +R + S
Sbjct: 676 DRKKKDKER----------EREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSG 725
Query: 916 YASSK---HRSKR-HKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSK 971
S K H S++ K S++ D S S S RS S + S+ + +++ SRSRS
Sbjct: 726 SISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEK-KAKKPKHSRSRSV 784
Query: 972 RRSRSTTAHSWQRSRSYSRDR 992
+S+ + + ++ +S SR R
Sbjct: 785 EKSQRSGKKASRKHKSKSRSR 805
Score = 44.7 bits (104), Expect = 7e-04
Identities = 45/192 (23%), Positives = 73/192 (38%), Gaps = 15/192 (7%)
Query: 664 SKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSA 723
++ RS R K + S + KHK + +E+ K E K +K+K K+ +
Sbjct: 629 NRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQ 688
Query: 724 PADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGG 783
E+ + E S +QDD +R +E S G H
Sbjct: 689 DKRKEKQKREEKDFKFS---------SQDDRLKRKRESERTFS---RSGSISVKIIRHDS 736
Query: 784 RKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEE 843
R+ + ++ +G+ S RSS S SS ++ + R SQ S ++
Sbjct: 737 RQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKA-- 794
Query: 844 DSGSEHSRSRSR 855
S S+SRSR
Sbjct: 795 -SRKHKSKSRSR 805
Score = 42.0 bits (97), Expect = 0.004
Identities = 86/402 (21%), Positives = 140/402 (34%), Gaps = 109/402 (27%)
Query: 732 KPEPPGSGSPAPPRRRRRAQ----------------------DDSQRRSLPA------EE 763
+P PPG PAPP+ RR D +RR+LPA E+
Sbjct: 185 QPGPPGP--PAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEK 242
Query: 764 GSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDA 823
K+ + Q K + + G + RS S D ++ +A
Sbjct: 243 MEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEA 302
Query: 824 SSHRLHQKSPSQYSEEEEEEDSGSEHS--------------------------------- 850
+S +SPS +EE + +E
Sbjct: 303 ASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAH 362
Query: 851 RSRSRSGRRHSSHRSSRRSYS--------SSSDASSDQSCYSRQRSYSDDSYSDYSDRSR 902
R +++ + + S+ S + S D+ ++S + S +DD + R +
Sbjct: 363 RKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQK 422
Query: 903 -----RHSKRSHDSDDSDYASSKHRSKRHKYSSSD----DDYSLSCSQSRSRSRSHTRER 953
R K D K +++R ++ + SLS ++R E+
Sbjct: 423 QEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEK 482
Query: 954 SRS-------------------RGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSR 994
R+ +GRSRS S S S SR+++ S S SYS S
Sbjct: 483 KRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYS-SSSG 541
Query: 995 STRSPSQRSGSRKRSWGHESPEERHS-GRRDFIRSKIYRSQS 1035
S+R+ S RS S KR ++RHS R I+++ RS+S
Sbjct: 542 SSRT-SSRSSSPKR-------KKRHSRSRSPTIKARRSRSRS 575
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sapiens]
Length = 805
Score = 88.2 bits (217), Expect = 5e-17
Identities = 99/373 (26%), Positives = 156/373 (41%), Gaps = 44/373 (11%)
Query: 786 HKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQK--SPSQYSEE-EEE 842
H ++ Q TK + H+ Q S ++ +A +++K +P++ + E +
Sbjct: 437 HDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPK 496
Query: 843 EDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSR 902
++ + + RSRSG S SS SS+S S S S S S S R +
Sbjct: 497 KEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKK 556
Query: 903 RHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSL---------SCSQSRSRSRSHTRER 953
RHS+ + + + S+ S+R K S+ + S + R R+RS +RER
Sbjct: 557 RHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRER 616
Query: 954 SRSRGRS---RSSSCSRSRSKRRSR--------STTAHSW-----------QRSRSYSRD 991
RSR RS R++ SRSRS+ R + S +H +RSRS +D
Sbjct: 617 RRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKD 676
Query: 992 RSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKD 1051
R + + + RK E + + S + D ++ K R + RSG +
Sbjct: 677 RKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRK--RESERTFSRSGSISVKIIRH 734
Query: 1052 DGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEE 1111
D R D K+T +++S +G S G S E S K K + K R SV E+
Sbjct: 735 DSRQDSKKST---TKDSKKHSGSDSSGRSSSESPGSSKEK----KAKKPKHSRSRSV-EK 786
Query: 1112 VQATPNKAGPKLK 1124
Q + KA K K
Sbjct: 787 SQRSGKKASRKHK 799
Score = 80.1 bits (196), Expect = 1e-14
Identities = 77/332 (23%), Positives = 132/332 (39%), Gaps = 27/332 (8%)
Query: 611 PNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTG--RSLPSKKER 668
PN++ V K + SGS+ SG + S S T + S
Sbjct: 486 PNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT 545
Query: 669 SGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKK--RKRKKNKSSAPAD 726
S +S K+KK+H +S K + S+ E ++ R K +R+ N++S +
Sbjct: 546 SSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERE 605
Query: 727 SERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKK--DEGGGGSSSQDHGGR 784
R + SP+ RRR R++ +R + + S ++ D+ G S H
Sbjct: 606 RRR--------NRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSH--- 654
Query: 785 KHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEED 844
KHKGE +R+ RS + + + + D + ++ ++S +++
Sbjct: 655 KHKGEAKEQ--ERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLK 712
Query: 845 SGSEHSRSRSRSGR------RHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYS 898
E R+ SRSG RH S + S++S + S S R S S S +
Sbjct: 713 RKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKK 772
Query: 899 DRSRRHSKRSHDSDDSDYASSKHRSKRHKYSS 930
+ +HS+ S + S K S++HK S
Sbjct: 773 AKKPKHSRSR--SVEKSQRSGKKASRKHKSKS 802
Score = 73.9 bits (180), Expect = 1e-12
Identities = 136/618 (22%), Positives = 229/618 (37%), Gaps = 111/618 (17%)
Query: 452 QGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKK---ALGGD---VSDQSLESHSQKVSET 505
+G EK E ++ ++ M + SK E K A GGD + +S ++ +T
Sbjct: 238 EGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDT 297
Query: 506 QMCESNSS-KETSLATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTK---A 561
+ E+ SS K T +P +E P E T + ++++ TK
Sbjct: 298 ENVEAASSGKVTRSPSPVPQEEHSDP--------------EMTEEEKEYQMMLLTKMLLT 343
Query: 562 EPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEK 621
E + + +Y+ K DA K T+ P +K++
Sbjct: 344 EILLDVTDEEIYYVAK-----DAHRKATKAP---------------------AKQLAQSS 377
Query: 622 IVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTG--RSLPSKKERSGKSHRHKKKK 679
+ S G GS S +++ GS S+T+D + K+E + + ++
Sbjct: 378 ALASLTGLGGLGGYGSGDSE-DERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLL 436
Query: 680 KHKKSSKHKRKHKADTEEKSSKAESGEKSKKR-----------KKRKRKKNKSSAPADSE 728
K+ + K++ + T+E + + S ++KR N++++ + +
Sbjct: 437 HDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPK 496
Query: 729 RGPKPEPP------GSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHG 782
+ K + GS S R S S + SSG SS +
Sbjct: 497 KEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK- 555
Query: 783 GRKHKGELPPSSCQRRAGTKRSSR----SSHRSQPSSGDEDSDDASS---HRLHQKSPSQ 835
++H P+ RR+ ++ SR S+R++ D + +S R +SPS+
Sbjct: 556 -KRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSR 614
Query: 836 Y---SEEEEEEDSGSEHSRSRSRSGRRHSSHRS--SRRSYSSSSDASSDQSCYSRQRSYS 890
S + + SRSRSR R+ R S S+ +A + R RS
Sbjct: 615 ERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSID 674
Query: 891 DDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDD----------DYSLSCS 940
D +R R KR K K K+SS DD +S S S
Sbjct: 675 KDRKKKDKEREREQDKRKE--------KQKREEKDFKFSSQDDRLKRKRESERTFSRSGS 726
Query: 941 --------QSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDR 992
SR S+ T + S+ S SS S S S S+ A + SRS S ++
Sbjct: 727 ISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEK 786
Query: 993 S-RSTRSPSQRSGSRKRS 1009
S RS + S++ S+ RS
Sbjct: 787 SQRSGKKASRKHKSKSRS 804
Score = 64.3 bits (155), Expect = 8e-10
Identities = 69/321 (21%), Positives = 124/321 (38%), Gaps = 16/321 (4%)
Query: 676 KKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEP 735
K+ K+ +K + + + S+ S S + SS + PK +
Sbjct: 497 KEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKK 556
Query: 736 PGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSC 795
S S +P + RR++ S R + E + K S+ + + P
Sbjct: 557 RHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRER 616
Query: 796 QRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSR 855
+R R R++ S+ S D D L S ++ E +E++ E SRS +
Sbjct: 617 RRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNS-HKHKGEAKEQERKKERSRSIDK 675
Query: 856 SGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSD 915
++ R + D+ ++R D +S DR +R + S
Sbjct: 676 DRKKKDKER----------EREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSG 725
Query: 916 YASSK---HRSKR-HKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSK 971
S K H S++ K S++ D S S S RS S + S+ + +++ SRSRS
Sbjct: 726 SISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEK-KAKKPKHSRSRSV 784
Query: 972 RRSRSTTAHSWQRSRSYSRDR 992
+S+ + + ++ +S SR R
Sbjct: 785 EKSQRSGKKASRKHKSKSRSR 805
Score = 44.7 bits (104), Expect = 7e-04
Identities = 45/192 (23%), Positives = 73/192 (38%), Gaps = 15/192 (7%)
Query: 664 SKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSA 723
++ RS R K + S + KHK + +E+ K E K +K+K K+ +
Sbjct: 629 NRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQ 688
Query: 724 PADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGG 783
E+ + E S +QDD +R +E S G H
Sbjct: 689 DKRKEKQKREEKDFKFS---------SQDDRLKRKRESERTFS---RSGSISVKIIRHDS 736
Query: 784 RKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEE 843
R+ + ++ +G+ S RSS S SS ++ + R SQ S ++
Sbjct: 737 RQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKA-- 794
Query: 844 DSGSEHSRSRSR 855
S S+SRSR
Sbjct: 795 -SRKHKSKSRSR 805
Score = 42.0 bits (97), Expect = 0.004
Identities = 86/402 (21%), Positives = 140/402 (34%), Gaps = 109/402 (27%)
Query: 732 KPEPPGSGSPAPPRRRRRAQ----------------------DDSQRRSLPA------EE 763
+P PPG PAPP+ RR D +RR+LPA E+
Sbjct: 185 QPGPPGP--PAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEK 242
Query: 764 GSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDA 823
K+ + Q K + + G + RS S D ++ +A
Sbjct: 243 MEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEA 302
Query: 824 SSHRLHQKSPSQYSEEEEEEDSGSEHS--------------------------------- 850
+S +SPS +EE + +E
Sbjct: 303 ASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAH 362
Query: 851 RSRSRSGRRHSSHRSSRRSYS--------SSSDASSDQSCYSRQRSYSDDSYSDYSDRSR 902
R +++ + + S+ S + S D+ ++S + S +DD + R +
Sbjct: 363 RKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQK 422
Query: 903 -----RHSKRSHDSDDSDYASSKHRSKRHKYSSSD----DDYSLSCSQSRSRSRSHTRER 953
R K D K +++R ++ + SLS ++R E+
Sbjct: 423 QEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEK 482
Query: 954 SRS-------------------RGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSR 994
R+ +GRSRS S S S SR+++ S S SYS S
Sbjct: 483 KRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYS-SSSG 541
Query: 995 STRSPSQRSGSRKRSWGHESPEERHS-GRRDFIRSKIYRSQS 1035
S+R+ S RS S KR ++RHS R I+++ RS+S
Sbjct: 542 SSRT-SSRSSSPKR-------KKRHSRSRSPTIKARRSRSRS 575
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 87.8 bits (216), Expect = 7e-17
Identities = 100/318 (31%), Positives = 133/318 (41%), Gaps = 31/318 (9%)
Query: 676 KKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKK----NKSSAPADSERGP 731
+K K+ ++ KH KA EEK+ SG +S+++++ R+K K S P+ + R
Sbjct: 240 RKDKEEAEAIKHA---KALEEEKA--MYSGRRSRRQRREFREKRLRGRKISPPSYARRDS 294
Query: 732 KPEPPGSGSP----APPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGG-RKH 786
P SP + R R R+ + + G +E +++ G
Sbjct: 295 PTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTG 354
Query: 787 KGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSG 846
K PP G S+R RS SS + SS R +S S+ SG
Sbjct: 355 KPPAPPQPGGPAPGRNASAR--RRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSG 412
Query: 847 SEHSRSRSRSGRRHSSH-----RSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRS 901
H+RSRSRS R S RS R S S D YSR S Y R
Sbjct: 413 -RHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSR----SPARRGGYGPR- 466
Query: 902 RRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRS--RSRSHTRERSRSRGR 959
RR RSH D Y + H S S +SLS S+SRS RSRSH+ S+SR R
Sbjct: 467 RRSRSRSHSGD--RYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSR 524
Query: 960 SRSSSCSRSRSKRRSRST 977
SRS S S S S R + T
Sbjct: 525 SRSRSQSPSPSPAREKLT 542
Score = 74.3 bits (181), Expect = 8e-13
Identities = 94/396 (23%), Positives = 145/396 (36%), Gaps = 43/396 (10%)
Query: 661 SLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNK 720
S PS R ++ K+ + SS+ + + ++ T + K +
Sbjct: 285 SPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAA 344
Query: 721 SSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQD 780
++A + G P PP G PAP R + S S + +S + S S+
Sbjct: 345 AAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRR 404
Query: 781 HGG----RKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQY 836
GG +H S + R+ ++R SRS R + SG D HR + +SP++
Sbjct: 405 GGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRD---GHR-YSRSPARR 460
Query: 837 SEEEEEEDSGS-EHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYS-DDSY 894
S S HS R R G R H SS RS SS S + S +R RS+S S
Sbjct: 461 GGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQ 520
Query: 895 SDYSDRSRRHS-----------------------KRSHDSDDSDYASSK------HRSKR 925
S RSR S K++ + + ++K + K
Sbjct: 521 SRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKL 580
Query: 926 HKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRS 985
+ + + ++ + ER R+ + +R R W+
Sbjct: 581 RMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWE-- 638
Query: 986 RSYSR-DRSRSTRSPSQRSGSRKRSWGH-ESPEERH 1019
R YSR RS S R + S SR+RS SP RH
Sbjct: 639 RQYSRQSRSPSPRYSREYSSSRRRSRSRSRSPHYRH 674
Score = 69.7 bits (169), Expect = 2e-11
Identities = 109/410 (26%), Positives = 156/410 (38%), Gaps = 91/410 (22%)
Query: 796 QRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSR 855
QRR ++ R S PS DS ++ +++SPS+ S E SRSRSR
Sbjct: 270 QRREFREKRLRGRKISPPSYARRDSP---TYDPYKRSPSESSSE----------SRSRSR 316
Query: 856 SGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDY---------------SDR 900
S + R + ++ +S S +++ + + + + +
Sbjct: 317 SP---TPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASA 373
Query: 901 SRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRS 960
RR S S S S +SS+ S+ S Y S +RSRSRS +R RSRSR S
Sbjct: 374 RRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYS 433
Query: 961 RSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSG----SRKRSWGHESPE 1016
R SRSR +R S SRD R +RSP++R G R RS H
Sbjct: 434 R----SRSRGRRHSGGG-----------SRDGHRYSRSPARRGGYGPRRRSRSRSHSGDR 478
Query: 1017 ERHSGR----RDFIRSKIYRSQSPHYFRS---GRGEGPGKKDDGRGDDSKATGPPSQNSN 1069
R GR RS+ S SP RS R P PSQ+ +
Sbjct: 479 YRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPS---------------PSQSRS 523
Query: 1070 IGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKDPPQG 1129
R SP EK+ + P+V E+++ T AG + G
Sbjct: 524 RSRSRSQSPSPSP----------AREKL--TRPAASPAVGEKLKKTEPAAGKE-----TG 566
Query: 1130 YFGPKLPPSLGNKPVLPLIGKLPATRKPNKKCEESGLERGEEQEQSETEE 1179
PKL P K L + L K +KK + + + E + Q +E
Sbjct: 567 AAKPKLTPQ--EKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDE 614
Score = 52.4 bits (124), Expect = 3e-06
Identities = 85/389 (21%), Positives = 133/389 (34%), Gaps = 69/389 (17%)
Query: 605 GLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPS 664
G+ G+P + GG R++ R + +S S+ S S S + + RS S
Sbjct: 350 GVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSS--------ASRTSSSRSSSRS-SS 400
Query: 665 KKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAP 724
+ R G +R S +H R S++ S +S+ R +R +
Sbjct: 401 RSRRGGGYYR---------SGRHAR----------SRSRSWSRSRSRSRRYSRSR----- 436
Query: 725 ADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGR 784
RG + GS +D + PA G G + S S+ H G
Sbjct: 437 ---SRGRRHSGGGS------------RDGHRYSRSPARRGGYGPRRR----SRSRSHSGD 477
Query: 785 KHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEED 844
+++ + G + S S RS S S + R H SPSQ
Sbjct: 478 RYR--------RGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRS 529
Query: 845 SGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRH 904
S +R + R +S + + A + + + + R
Sbjct: 530 QSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQ 589
Query: 905 SKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSS 964
K D A K + H+ +D+ + R + R RE+ R + S
Sbjct: 590 FKA-----DKKAAQEKMIQQEHERQEREDELRAMARKIRMKERER-REKEREEWERQYSR 643
Query: 965 CSRSRSKRRSRSTTAHSWQRSRSYSRDRS 993
SRS S R SR +S R RS SR RS
Sbjct: 644 QSRSPSPRYSRE---YSSSRRRSRSRSRS 669
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 87.0 bits (214), Expect = 1e-16
Identities = 171/702 (24%), Positives = 253/702 (36%), Gaps = 64/702 (9%)
Query: 643 NKQEPGGSHGSETEDTGRSLPSKKERSGKSH-RHKKKKKHKKSSKHKRKHKADTEEKSSK 701
N + GG +G PS S S RH+ KHK+ HK KH D + +
Sbjct: 3 NSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKR---HKSKHSKDMGLVTPE 59
Query: 702 AES-GEKSKKRKKRKRKKNKSSAPADS-----ERGPKPEPPGSGSPAPPRRRRRAQDDSQ 755
A S G K + + S +D +R E GS + R Q
Sbjct: 60 AASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRS 119
Query: 756 RRSLPAEEGSSGKKDEGGGGSSSQDH---GGRKHKGELPPS--SCQRRAGTKRSSRSSHR 810
R L A++ K E S S G K E Q + + SRSS
Sbjct: 120 RDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKL 179
Query: 811 SQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSY 870
+ + E + S H+ +S S E + + + RSRS R S S +
Sbjct: 180 HKEKTRKE-RELKSGHK--DRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDS 236
Query: 871 SSSSDASSDQSCYSRQRSYSDDSYSDYS----DRSRRHSKRSHDSDDSDYASS-KHRSKR 925
S + D S RS++ +Y Y SRR S + S Y SS + S
Sbjct: 237 PSGASYGQDYDL-SPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPY 295
Query: 926 HKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRS-RSKRRSRSTTAHSWQ- 983
+ S YS S S RS S++ GR RSSS S RS RS + S +
Sbjct: 296 SRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKS 355
Query: 984 RSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGR 1043
RSRS + R S+ S +RS SR R H S + +++ R + +
Sbjct: 356 RSRSPAYSRHSSSHSKKKRSSSRSR---HSSISPVRLPLNSSLGAELSRKKKERAAAAAA 412
Query: 1044 GEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVE 1103
+ GK+ G S P +NS++ D E K + L + ++
Sbjct: 413 AKMDGKESKG----SPVFLPRKENSSV-----EAKDSGLESKKLPRSVKLEKSAPDTELV 463
Query: 1104 RKPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLGNKPVLPLIGKLPATRKPNKKCEE 1163
++ EV+ + + KL + + + L K TR +
Sbjct: 464 NVTHLNTEVKNSSDTGKVKLDENSEKHLVKDL--------------KAQGTRDSKPIALK 509
Query: 1164 SGLERGEEQEQSETEEGPPGSSDALFGHQFPSEETTGPLLDPPPEESKSGEATADHPVAP 1223
+ +E E SE E PP + A P+ TT P PP A P P
Sbjct: 510 EEIVTPKETETSEKETPPPLPTIASPPPPLPT--TTPPPQTPPLPPLPPIPALPQQPPLP 567
Query: 1224 LGTPAHSDCYPGDPTISHNYLPDPSDGDT-LESLDSSSQPGPVESSL---LPIAPDLEHF 1279
PA S P S + LP + T S ++SQP PV+ S+ + + + H
Sbjct: 568 PSQPAFSQV----PASSTSTLPPSTHSKTSAVSSQANSQP-PVQVSVKTQVSVTAAIPHL 622
Query: 1280 -PSYAPPSGDPSIESTDGAEDASLAPLESQPITFTPEEMEKY 1320
S PP P + D D+ L S+P+ E+ ++
Sbjct: 623 KTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRH 664
Score = 36.2 bits (82), Expect = 0.25
Identities = 89/457 (19%), Positives = 157/457 (34%), Gaps = 59/457 (12%)
Query: 347 GDSDGSSNLDGKKEDEDPQDGGSLAST------LSKLKR--MKREEGAGATEPEY----- 393
G DGS G + P GG +++ +SK KR K + G PE
Sbjct: 9 GKKDGSGGASGTLQ---PSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEAASLGT 65
Query: 394 -------YHYIPPAHCKVKPNFPFLLFMRASEQMDGDNTT----------HPKNAPESKK 436
Y I + F L R +++ G + + H ++ K
Sbjct: 66 VIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSRDLLKA 125
Query: 437 GSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLE 496
+ K KS ++ S + +S S++ E E +A+ A +S +
Sbjct: 126 KQTEKEKSQEVSSKSGSMKDRISGSSKRSNE-------ETDDYGKAQVAKSSSKESRSSK 178
Query: 497 SHSQKVSETQMCESN----SSKETSLATPAGKESQEGPKHPTGPFFPVLSKDESTALQWP 552
H +K + + +S S TP ++ + PK + S D S P
Sbjct: 179 LHKEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWS-DSSKQDDSP 237
Query: 553 SELLIFTKAEPSISYSCNPLYFD-FKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEP 611
S + S S S +D +K S +R + P S+ + + P
Sbjct: 238 SGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYS- 296
Query: 612 NKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGK 671
+ + V RSS SG + S ++ S+ + LPS+K +
Sbjct: 297 RRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSR 356
Query: 672 SH-----RHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPAD 726
S RH KK S + +H + + + S RKK++R ++A D
Sbjct: 357 SRSPAYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMD 416
Query: 727 SERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEE 763
+ GSP R+ + +++ L +++
Sbjct: 417 GKE-------SKGSPVFLPRKENSSVEAKDSGLESKK 446
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 87.0 bits (214), Expect = 1e-16
Identities = 171/702 (24%), Positives = 253/702 (36%), Gaps = 64/702 (9%)
Query: 643 NKQEPGGSHGSETEDTGRSLPSKKERSGKSH-RHKKKKKHKKSSKHKRKHKADTEEKSSK 701
N + GG +G PS S S RH+ KHK+ HK KH D + +
Sbjct: 3 NSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKR---HKSKHSKDMGLVTPE 59
Query: 702 AES-GEKSKKRKKRKRKKNKSSAPADS-----ERGPKPEPPGSGSPAPPRRRRRAQDDSQ 755
A S G K + + S +D +R E GS + R Q
Sbjct: 60 AASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRS 119
Query: 756 RRSLPAEEGSSGKKDEGGGGSSSQDH---GGRKHKGELPPS--SCQRRAGTKRSSRSSHR 810
R L A++ K E S S G K E Q + + SRSS
Sbjct: 120 RDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKL 179
Query: 811 SQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSY 870
+ + E + S H+ +S S E + + + RSRS R S S +
Sbjct: 180 HKEKTRKE-RELKSGHK--DRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDS 236
Query: 871 SSSSDASSDQSCYSRQRSYSDDSYSDYS----DRSRRHSKRSHDSDDSDYASS-KHRSKR 925
S + D S RS++ +Y Y SRR S + S Y SS + S
Sbjct: 237 PSGASYGQDYDL-SPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPY 295
Query: 926 HKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRS-RSKRRSRSTTAHSWQ- 983
+ S YS S S RS S++ GR RSSS S RS RS + S +
Sbjct: 296 SRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKS 355
Query: 984 RSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGR 1043
RSRS + R S+ S +RS SR R H S + +++ R + +
Sbjct: 356 RSRSPAYSRHSSSHSKKKRSSSRSR---HSSISPVRLPLNSSLGAELSRKKKERAAAAAA 412
Query: 1044 GEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVE 1103
+ GK+ G S P +NS++ D E K + L + ++
Sbjct: 413 AKMDGKESKG----SPVFLPRKENSSV-----EAKDSGLESKKLPRSVKLEKSAPDTELV 463
Query: 1104 RKPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLGNKPVLPLIGKLPATRKPNKKCEE 1163
++ EV+ + + KL + + + L K TR +
Sbjct: 464 NVTHLNTEVKNSSDTGKVKLDENSEKHLVKDL--------------KAQGTRDSKPIALK 509
Query: 1164 SGLERGEEQEQSETEEGPPGSSDALFGHQFPSEETTGPLLDPPPEESKSGEATADHPVAP 1223
+ +E E SE E PP + A P+ TT P PP A P P
Sbjct: 510 EEIVTPKETETSEKETPPPLPTIASPPPPLPT--TTPPPQTPPLPPLPPIPALPQQPPLP 567
Query: 1224 LGTPAHSDCYPGDPTISHNYLPDPSDGDT-LESLDSSSQPGPVESSL---LPIAPDLEHF 1279
PA S P S + LP + T S ++SQP PV+ S+ + + + H
Sbjct: 568 PSQPAFSQV----PASSTSTLPPSTHSKTSAVSSQANSQP-PVQVSVKTQVSVTAAIPHL 622
Query: 1280 -PSYAPPSGDPSIESTDGAEDASLAPLESQPITFTPEEMEKY 1320
S PP P + D D+ L S+P+ E+ ++
Sbjct: 623 KTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRH 664
Score = 36.2 bits (82), Expect = 0.25
Identities = 89/457 (19%), Positives = 157/457 (34%), Gaps = 59/457 (12%)
Query: 347 GDSDGSSNLDGKKEDEDPQDGGSLAST------LSKLKR--MKREEGAGATEPEY----- 393
G DGS G + P GG +++ +SK KR K + G PE
Sbjct: 9 GKKDGSGGASGTLQ---PSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEAASLGT 65
Query: 394 -------YHYIPPAHCKVKPNFPFLLFMRASEQMDGDNTT----------HPKNAPESKK 436
Y I + F L R +++ G + + H ++ K
Sbjct: 66 VIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSRDLLKA 125
Query: 437 GSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLE 496
+ K KS ++ S + +S S++ E E +A+ A +S +
Sbjct: 126 KQTEKEKSQEVSSKSGSMKDRISGSSKRSNE-------ETDDYGKAQVAKSSSKESRSSK 178
Query: 497 SHSQKVSETQMCESN----SSKETSLATPAGKESQEGPKHPTGPFFPVLSKDESTALQWP 552
H +K + + +S S TP ++ + PK + S D S P
Sbjct: 179 LHKEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWS-DSSKQDDSP 237
Query: 553 SELLIFTKAEPSISYSCNPLYFD-FKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEP 611
S + S S S +D +K S +R + P S+ + + P
Sbjct: 238 SGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYS- 296
Query: 612 NKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGK 671
+ + V RSS SG + S ++ S+ + LPS+K +
Sbjct: 297 RRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSR 356
Query: 672 SH-----RHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPAD 726
S RH KK S + +H + + + S RKK++R ++A D
Sbjct: 357 SRSPAYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMD 416
Query: 727 SERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEE 763
+ GSP R+ + +++ L +++
Sbjct: 417 GKE-------SKGSPVFLPRKENSSVEAKDSGLESKK 446
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 82.8 bits (203), Expect = 2e-15
Identities = 132/607 (21%), Positives = 219/607 (36%), Gaps = 89/607 (14%)
Query: 676 KKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKN-KSSAPADSERGPKPE 734
++K ++ +++++ + + A +G ++K+ +R+RK++ ++ A S G +P
Sbjct: 483 RRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPA 542
Query: 735 PPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSS 794
PP SP ++ R R P SS + S S+ R S+
Sbjct: 543 PPAPASPWDSKKHR------SRDRKPGSHASSSARRRSRSRSRSRSTRRRSR------ST 590
Query: 795 CQRRAGTKRS-SRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSR 853
+RR G++RS SR R + S +SS S + + + GS+ + R
Sbjct: 591 DRRRGGSRRSRSREKRRRRRRSASPPPATSSS----SSSRRERHRGKHRDGGGSKKKKKR 646
Query: 854 SRSGRRHSSHRSSRRSYSSSSDASSDQSCY---SRQRSYSDDSYSDYSDRSRRHSKRSHD 910
SRS S S ++ + + S SC SR+R S D +D KR+
Sbjct: 647 SRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTIT 706
Query: 911 SDDSDYASSKHRSKRHKYSSSD----DDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCS 966
D + + S S D LS + +S R RS G + SSS S
Sbjct: 707 VGRLDKSDPRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRS---GAASSSSSS 763
Query: 967 RSRSKRRSRSTTAHSWQRSRSYSRDRSRST---RSPSQRSGSR--------KRSWGHESP 1015
R + RR ++ R R RDR RS+ R P + + S G S
Sbjct: 764 REKGSRR-KALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSS 822
Query: 1016 EERHSGRRDFIRSKI-------YRSQSPHYFRSGRGEGPGKKDDGRGDDSKATG-PPSQN 1067
S R+ ++SK+ S +P + G G R +S++ P +
Sbjct: 823 SSSCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGSIGVKFSRDRESRSPFLKPDER 882
Query: 1068 SNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVS------------------ 1109
+ + + G P+ K V AK +K + K + KPS +
Sbjct: 883 APTEMAKAAPGSTKPK-KTKVKAKAGAKKTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVS 941
Query: 1110 ------------------EEVQATPNKAGPKLKDPPQGYFGPKLPPSLGNKPVLPLIGKL 1151
EE + + K+ P P P + + K
Sbjct: 942 LKKSKADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPKAAPPPPALTPDSQTVDSSCKT 1001
Query: 1152 PATR-KPNKKCEESGLERGEEQEQSETEEGPPGSSDALFGHQFPSEETTGPLLDPPPEES 1210
P P + EE+G+ G E+E+ E EE + Q P+ T P +
Sbjct: 1002 PEVSFLPEEATEEAGVRGGAEEEEEEEEEEEEEEEEE---EQQPATTTATSTAAAAPSTA 1058
Query: 1211 KSGEATA 1217
S +TA
Sbjct: 1059 PSAGSTA 1065
Score = 70.1 bits (170), Expect = 2e-11
Identities = 102/469 (21%), Positives = 177/469 (37%), Gaps = 50/469 (10%)
Query: 579 SRNKDART-KGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGS 637
+R K R K + + K+ SSS G P P + +K RS + + AS S
Sbjct: 515 TRKKSRRERKRSGEAKEAASSSS----GTQPAPPAPASPWDSKKH-RSRDRKPGSHASSS 569
Query: 638 ACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEE 697
A + S + T R S R G S R + ++K ++ + A +
Sbjct: 570 ARRRSRSR-------SRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSS 622
Query: 698 KSSKAE-------SGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRR--RR 748
SS+ E G SKK+KKR R + + + SE+ P P PP SGS + R RR
Sbjct: 623 SSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRR 682
Query: 749 RAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRR--------AG 800
R + L + + K+ G D G P SS +R +G
Sbjct: 683 RGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRG---PSPAPASSPKREVLYDSEGLSG 739
Query: 801 TKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRH 860
+R +SS + + SG S +S + ++ + + + D + RS ++
Sbjct: 740 EERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPK 799
Query: 861 SSHRSS----RRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDY 916
S SS + SS S +SS S S ++ + + + D+ +
Sbjct: 800 ESAPSSGPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGL 859
Query: 917 AS-----SKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRER-------SRSRGRSRSSS 964
S S+ R R + D+ +++ S + + +++G +
Sbjct: 860 GSIGVKFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKTKGTKGKTK 919
Query: 965 CSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHE 1013
S++R K RS + S + S + ++ S + G+ + SW E
Sbjct: 920 PSKTRKKVRSGGGSGGSGGQV-SLKKSKADSCSQAAGTKGAEETSWSGE 967
Score = 41.2 bits (95), Expect = 0.008
Identities = 66/348 (18%), Positives = 123/348 (35%), Gaps = 57/348 (16%)
Query: 579 SRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSA 638
S KD R G + LD G+ ++ ++ ++ S R P SA
Sbjct: 746 SSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKAR---PPKESA 802
Query: 639 CSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEK 698
S +P S GS + + S S+K K K + R+ + T
Sbjct: 803 PSSGPPPKPPVSSGSGSSSSSSSCSSRKV-----------KLQSKVAVLIREGVSSTTPA 851
Query: 699 SSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKP---EPPGSGSPAPPRRRRRAQDDSQ 755
A +G S K + ++++S ER P PGS P + + +A
Sbjct: 852 KDAASAGLGSIGVKFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKT 911
Query: 756 RRSLPAEEGS-SGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPS 814
+ + + S + KK GGGS GG+ + SC + AGTK + +S +
Sbjct: 912 KGTKGKTKPSKTRKKVRSGGGSGGS--GGQVSLKKSKADSCSQAAGTKGAEETSWSGEER 969
Query: 815 SG-------------------------------------DEDSDDASSHRLHQKSPSQYS 837
+ +E +++A ++ +
Sbjct: 970 AAKVPSTPPPKAAPPPPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAEEEEEEEE 1029
Query: 838 EEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSR 885
EEEEEE+ + + + + ++ ++ + S++ D+ ++ SR
Sbjct: 1030 EEEEEEEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPASR 1077
Score = 35.0 bits (79), Expect = 0.55
Identities = 62/233 (26%), Positives = 95/233 (40%), Gaps = 32/233 (13%)
Query: 301 SFSFAKKAPVKLESIASVFKDHAEEGTSEDGTKPDEKSSDQGLQKVG---DSDGSSNLDG 357
S S VKL+S +V EG S T P + ++ GL +G D S
Sbjct: 822 SSSSCSSRKVKLQSKVAVL---IREGVSS--TTPAKDAASAGLGSIGVKFSRDRESRSPF 876
Query: 358 KKEDED-PQDGGSLASTLSKLKRMKREEGAGATEPEYYHYIPPAHCKVKPNFPFLLFMRA 416
K DE P + A +K K+ K + AGA + + K KP+ +
Sbjct: 877 LKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKTK------GTKGKTKPS-------KT 923
Query: 417 SEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEP 476
+++ + S K S K SC +AA ++GAE+T S +E + PS P
Sbjct: 924 RKKVRSGGGSGGSGGQVSLKKS--KADSCSQAAGTKGAEET----SWSGEERAAKVPSTP 977
Query: 477 GSK-AEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQE 528
K A AL D Q+++S S K E +++E + A +E +E
Sbjct: 978 PPKAAPPPPALTPD--SQTVDS-SCKTPEVSFLPEEATEEAGVRGGAEEEEEE 1027
Score = 33.5 bits (75), Expect = 1.6
Identities = 36/133 (27%), Positives = 49/133 (36%), Gaps = 34/133 (25%)
Query: 721 SSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQD 780
S +P+ S P P PP PAPP R D P +E S + Q
Sbjct: 198 SPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFH----PTDEAYSPPP------APEQK 247
Query: 781 HGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEE 840
+ + G P SS AGT PS +E+ ++ + EE+
Sbjct: 248 YDPFEPTGSNPSSS----AGT-----------PSPEEEEEEE---------EEEEEEEED 283
Query: 841 EEEDSGSEHSRSR 853
EEE+ G S SR
Sbjct: 284 EEEEEGLSQSISR 296
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 82.4 bits (202), Expect = 3e-15
Identities = 137/623 (21%), Positives = 225/623 (36%), Gaps = 92/623 (14%)
Query: 402 CKVKPN-FPFLLFMRASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSE 460
CK +P+ FPF Q T K SK + + KS +K + + SE
Sbjct: 338 CKTEPSKFPF---PTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLK----DDLKLSSSE 390
Query: 461 VSEQPKETSMTEP-SEPGSKAEAK--KALGGDVSDQSLESHSQKVSETQMCESNSSKETS 517
S+ ++ T P S PGS +E + G D S SHS SE+ + S+ +S
Sbjct: 391 DSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSG--SESSSGSDSESESSS 448
Query: 518 LATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCN-PLYFDF 576
+ A + SQ P P D W +++ K P+ S N P +
Sbjct: 449 SDSEANEPSQSASPEPEPPPTNKWQLDN-----WLNKVNPH-KVSPASSVDSNIPSSQGY 502
Query: 577 KLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASG 636
K K+ R +GT S K+ PG +K+ + G E S GR +PA
Sbjct: 503 K----KEGREQGTGNSYTDTSGPKE-TSSATPGRDSKTIQKGSE----SGRGRQKSPAQS 553
Query: 637 SACSG---LNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKA 693
+ + + K++P + + E+ L + E +HK ++K RK
Sbjct: 554 DSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNI 613
Query: 694 DTEEKSSKAESGEKSK-KRKKRKRKKNKSSAPADSERGPKPE----PPGSGSPAPPRRRR 748
E KSS + EK K K + +K++ D+ E PP S +P P R
Sbjct: 614 KKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNR 673
Query: 749 R-------AQDDS---QRRSLPAEE-----------------------------GSSGKK 769
++DS QR P EE G K+
Sbjct: 674 TPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKE 733
Query: 770 DEGGGGS-----SSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDAS 824
E G +K E + +R+ + +R+S +P + D++S
Sbjct: 734 TEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHK 793
Query: 825 SHRLHQKSPSQYSEEEE----------EEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSS 874
+ S ++E++ +D +EH SR R+ + SS +SS S +S
Sbjct: 794 PSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHG-SRKRTISQSSSLKSSSNSNKETS 852
Query: 875 DASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDD 934
+S + S S+Q+ + S + + S + S + +R K D +
Sbjct: 853 GSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRN 912
Query: 935 YSLSCSQSRSRSRSHTRERSRSR 957
YS ++ H + R
Sbjct: 913 YSADHYLQEAKKLKHNADALSDR 935
Score = 68.6 bits (166), Expect = 4e-11
Identities = 133/614 (21%), Positives = 210/614 (34%), Gaps = 72/614 (11%)
Query: 663 PSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSS 722
PS E+S + ++ +SSK A + +S K SG +S +R + S
Sbjct: 84 PSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSG 143
Query: 723 APADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHG 782
+ +R + SGS + + + ++ R S P + + + S DH
Sbjct: 144 TNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHH 203
Query: 783 GRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQY-----S 837
++H+ P + S + S + S+ + QK P+ Y
Sbjct: 204 SKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQK-PTAYVRPMDG 262
Query: 838 EEEEEEDSGSEHSRSRSRSGRRHSSHRSSRR--------SYSSSSDASSDQSCYSRQRSY 889
+E E SEH S+S SS+ S + AS D SC
Sbjct: 263 QESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKE 322
Query: 890 SDDSY------------------------SDYSDRSRRHSKRSHDSDDSDYASSKHRSKR 925
S+ S S+ KR + S S+ SK K
Sbjct: 323 MTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKD 382
Query: 926 H-KYSSSDD-DYSLSCSQSRSRSR-------SHTRERSRSRGRSRSSSCSRSRSKRRSRS 976
K SSS+D D C ++ RS SH R SSS S S S S S
Sbjct: 383 DLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDS 442
Query: 977 TTAHSWQRSRSYSRDRSRSTR-SPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQS 1035
+ S S + +S S P + + +W ++ + S + S I SQ
Sbjct: 443 ESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASS-VDSNIPSSQG 501
Query: 1036 PHYFRSGRGEGPGKK---DDGRGDDSKAT-GPPSQNSNIGTGRGSEGDCSPEDKNSVTAK 1091
Y + GR +G G G + S AT G S+ G+ G SP +S T +
Sbjct: 502 --YKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQR 559
Query: 1092 LLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLGNKPVLPLIGKL 1151
+ K ++P +E+ A + G K++ +P S
Sbjct: 560 RTVGK-------KQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHK-------AAT 605
Query: 1152 PATRKPNKKCEESGLER--GEEQEQSETEEGPPGSSDALFGHQFPSEETTGPLLDPPPEE 1209
+RKPN K E R E+++ T + S + + S+ L P +
Sbjct: 606 KGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQT 665
Query: 1210 SKSGEATADHPVAP 1223
K E+ PV P
Sbjct: 666 PKYPESNRT-PVKP 678
Score = 55.8 bits (133), Expect = 3e-07
Identities = 115/539 (21%), Positives = 200/539 (37%), Gaps = 54/539 (10%)
Query: 224 DEEGGEDDKDESATNSGTGATASCGLGSEFSTDKGGPFTAVQITNTTGLAQAPGLASQGI 283
+ EG ++ +D+S+++SG+ +++ SE S+ N + +P
Sbjct: 417 NSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSE-------ANEPSQSASPEPEPPPT 469
Query: 284 SFGIKNNLGTPLQKLGV-SFSFAKKAPVKLESIASVFKDHAEEGTSE---DGTKPDEKSS 339
+ K L L K+ S A + S K+ E+GT D + P E SS
Sbjct: 470 N---KWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSS 526
Query: 340 -DQGLQKVGDSDGSSNLDGKKEDEDPQDGGSLASTLSKLKRMKREEGAGATEPEYYHYIP 398
G GS + G+++ D + T+ K K+ K+ E A A EP
Sbjct: 527 ATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGK-KQPKKAEKAAAEEPR------ 579
Query: 399 PAHCKVKPNFPFLLF--MRASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEK 456
K++ P L M +S + N + K SSP+P A + K
Sbjct: 580 -GGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESK-SSPRP------TAEKKKYK 631
Query: 457 TVSEVSEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKET 516
+ S+ S++ +E T+ S S E++ + + ES+ V + + E +S
Sbjct: 632 STSKSSQKSREIIETDTSSSDSD-ESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQ 690
Query: 517 SLATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDF 576
+ +P ++ P +P++ K +L + T+ P +
Sbjct: 691 RMFSPMEEKELLSPLSEPDDRYPLIVK---------IDLNLLTRIPGKPYKETEPPKGEK 741
Query: 577 KLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASG 636
K K R + + + + K + D ++SK+ E ++S G P+S
Sbjct: 742 KNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTED--KNSAGHK--PSSN 797
Query: 637 SACSGLNKQEPGGSHGSETEDTGRSLPSK--KERSGKSHRHKKKKKHKKSSKHKRKHKAD 694
S KQ G +PSK K G R + KSS + K +
Sbjct: 798 RESS---KQSAAKEKDLLPSPAG-PVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSG 853
Query: 695 TEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDD 753
+ + SS +K++ + K+ K AP+ S P P S PRR + DD
Sbjct: 854 SSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSK--PRRTKLVFDD 910
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 82.0 bits (201), Expect = 4e-15
Identities = 75/338 (22%), Positives = 136/338 (40%), Gaps = 29/338 (8%)
Query: 689 RKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRR 748
RK K D +E + + + + ++ + +R + +P S R G GS + R
Sbjct: 238 RKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRS-RSRSHHREGHGSSSFDRELE 296
Query: 749 RAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSS 808
R + + QR A+E ++ S S D G + RR+ ++ RS
Sbjct: 297 R-EKERQRLEREAKEREKERRR-----SRSIDRGLER-----------RRSRSRERHRSR 339
Query: 809 HRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRR 868
RS+ GD D + +++ + + ++E + E R RSR + R
Sbjct: 340 SRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVE 399
Query: 869 SYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKY 928
D + ++ S + +S R R+H RS + + S+ + K K+
Sbjct: 400 EKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKH 459
Query: 929 SSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSY 988
+ + S S+S S+ R+ + E+S+ R S S SR RS+ + RS+
Sbjct: 460 KNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSR-----------SKERSH 508
Query: 989 SRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFI 1026
RD S S + R +S ES E++H + + +
Sbjct: 509 KRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDETV 546
Score = 73.6 bits (179), Expect = 1e-12
Identities = 78/348 (22%), Positives = 128/348 (36%), Gaps = 56/348 (16%)
Query: 644 KQEPGGSHGSETEDTGRSLPSKKERSGK-------SHRHKKKKKHKKSSKHKRKHKADTE 696
K + G G+E D R + ++ RS + S R + + H + + E
Sbjct: 239 KIKKDGKEGAEEID--RHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELE 296
Query: 697 EKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQR 756
+ + ++K+R+K +R+ + R E S S + R+ R D +R
Sbjct: 297 REKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRER 356
Query: 757 RSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSG 816
+E G++ +D K +G +R + RS +
Sbjct: 357 E----KENERGRR---------RDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKH 403
Query: 817 DEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDA 876
ED DD R H+ +E++ S S + RSRS R++ RS RS SS
Sbjct: 404 KEDKDD----RRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKH 459
Query: 877 SSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYS 936
++ S +RS S +D + KR H
Sbjct: 460 KNESKEKSNKRSRSGSQ--GRTDSVEKSKKREH--------------------------- 490
Query: 937 LSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQR 984
S S+ +SR RS ++ERS R S S S +RRS+S S ++
Sbjct: 491 -SPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEK 537
Score = 57.4 bits (137), Expect = 1e-07
Identities = 72/284 (25%), Positives = 104/284 (36%), Gaps = 34/284 (11%)
Query: 838 EEEEEEDSGSEHSRSRS--------RSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSY 889
E EE D E RSRS RS RR S R + SSS + RQR
Sbjct: 246 EGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLE 305
Query: 890 SDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSH 949
+ + R R R + S + +HRS+ D + + R
Sbjct: 306 REAKEREKERRRSRSIDRGLERRRSR-SRERHRSRSRSRDRKGDRRDRDREREKENERGR 364
Query: 950 TRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRS 1009
R+R + R R RS+ RS+ QRSR ++ +R KR
Sbjct: 365 RRDRDYDKERGNEREKERERSRERSKE------QRSRGEVEEKKHKEDKDDRRHRDDKRD 418
Query: 1010 WGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDD--SKATGPPSQN 1067
E++HS R R + +RS+S R GK+ R + SK +
Sbjct: 419 ---SKKEKKHSRSRS--RERKHRSRS-------RSRNAGKRSRSRSKEKSSKHKNESKEK 466
Query: 1068 SNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEE 1111
SN + GS+G +K+ E S++ RK S S+E
Sbjct: 467 SNKRSRSGSQGRTDSVEKSKKR-----EHSPSKEKSRKRSRSKE 505
Score = 50.8 bits (120), Expect = 1e-05
Identities = 45/187 (24%), Positives = 74/187 (39%), Gaps = 14/187 (7%)
Query: 585 RTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNK 644
+ +G E+ K+ S + + GE + K + R + D+ ++
Sbjct: 372 KERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSR 431
Query: 645 QEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAES 704
+ S RS KE+S K H+++ K+K K S+ + + D+ EKS K E
Sbjct: 432 ERKHRSRSRSRNAGKRSRSRSKEKSSK-HKNESKEKSNKRSRSGSQGRTDSVEKSKKREH 490
Query: 705 GEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEG 764
+K +KR R K ER K + S + RRR+Q Q ++E
Sbjct: 491 SPSKEKSRKRSRSK---------ERSHKRDHSDSKDQSDKHDRRRSQSIEQE----SQEK 537
Query: 765 SSGKKDE 771
KDE
Sbjct: 538 QHKNKDE 544
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 82.0 bits (201), Expect = 4e-15
Identities = 87/248 (35%), Positives = 110/248 (44%), Gaps = 44/248 (17%)
Query: 763 EGSSGKKDEGGGGSSSQDHGGRKHKGE-LPPSSCQRRAGTKRSSRSSHRSQPSSG----- 816
E S G+ DE G +K++G+ + P+S + K S
Sbjct: 118 EESDGEYDEFGRKK-------KKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLD 170
Query: 817 -DEDSDDASSHRLHQKSPSQYS-EEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSS 874
DED DDA S+Y+ + EEEDS + S RSRS R S RSS RS S SS
Sbjct: 171 EDEDEDDADL--------SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSS 222
Query: 875 DASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDD 934
S SR RS S S S S R RS S S+ S+ H+ SSS
Sbjct: 223 SRSR-----SRSRSRSSSSSQSRSRSSSRERSRSRGS------KSRSSSRSHRGSSSPRK 271
Query: 935 YSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSR 994
S S S S + ER+R R RSRSSS S R KRR+RS + +R RS S
Sbjct: 272 RSYSSSSS-------SPERNRKRSRSRSSS-SGDRKKRRTRSRSPE--RRHRSSSGSSHS 321
Query: 995 STRSPSQR 1002
+RS S++
Sbjct: 322 GSRSSSKK 329
Score = 76.3 bits (186), Expect = 2e-13
Identities = 66/220 (30%), Positives = 93/220 (42%), Gaps = 15/220 (6%)
Query: 829 HQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRS------SRRSYSSSSDASSDQSC 882
+++ +Y E EE + E R + + + S + S D D S
Sbjct: 107 NERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSK 166
Query: 883 YSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQS 942
Y +D D +D S+ + S + D S+K +S R S S +S S S+S
Sbjct: 167 YK----LDEDEDEDDADLSKYNLDASEEED-----SNKKKSNRRSRSKSRSSHSRSSSRS 217
Query: 943 RSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQR 1002
S S S +R RSRSR S S S SRS S+ RSRS + S SRS+ S RS S
Sbjct: 218 SSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSS 277
Query: 1003 SGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSG 1042
S S +R+ SG R R++ + H SG
Sbjct: 278 SSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSG 317
Score = 74.3 bits (181), Expect = 8e-13
Identities = 73/214 (34%), Positives = 97/214 (45%), Gaps = 25/214 (11%)
Query: 812 QPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYS 871
+ S G+ D + K+ S +E ED SE S +
Sbjct: 118 EESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDE------DEDLSKYKLDE 171
Query: 872 SSSDASSDQSCYSRQRSYSDDSYSDYSDR-SRRHSKRSH---DSDDSDYASSKHRSKRHK 927
+ +D S Y+ S +DS S+R SR S+ SH S S +SS+ RS+
Sbjct: 172 DEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRS 231
Query: 928 YSSSDDDYSLSCSQSRSRSRSHTRERSRSRG-RSRSSSCS-RSRSKRRSRSTTAHSWQRS 985
SS S S+SRSRS +RERSRSRG +SRSSS S R S R RS ++ S
Sbjct: 232 RSS---------SSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPE 282
Query: 986 RSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERH 1019
R+ R RSRS+ S + +KR SPE RH
Sbjct: 283 RNRKRSRSRSSSSGDR----KKRRTRSRSPERRH 312
Score = 61.2 bits (147), Expect = 7e-09
Identities = 50/197 (25%), Positives = 81/197 (41%), Gaps = 15/197 (7%)
Query: 666 KERSGKSHRHKKKKKHKKSSKHKRKHKADTEE---KSSKAESGEKSKKRKKRKRKKNKSS 722
KE K +++ + + SK+K D ++ ++ E+ KK+ ++++S
Sbjct: 146 KEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSK 205
Query: 723 APADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHG 782
+ + R S S + R R R+ SQ RS SS ++ GS S+
Sbjct: 206 SRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRS-----RSSSRERSRSRGSKSRS-S 259
Query: 783 GRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEE 842
R H+G P +R + SS +R + S S D R +SP E
Sbjct: 260 SRSHRGSSSPR--KRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSP----ERRHR 313
Query: 843 EDSGSEHSRSRSRSGRR 859
SGS HS SRS S ++
Sbjct: 314 SSSGSSHSGSRSSSKKK 330
Score = 60.1 bits (144), Expect = 2e-08
Identities = 57/205 (27%), Positives = 81/205 (39%), Gaps = 29/205 (14%)
Query: 666 KERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRK--KRKRKKNKSSA 723
KE G+ + K + + + AD + + A E S K+K +R R K++SS
Sbjct: 151 KESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSH 210
Query: 724 PADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGG 783
S R P S S + R R R+ SQ RS SS ++ GS S+
Sbjct: 211 SRSSSRSSSP----SSSRSRSRSRSRSSSSSQSRSR-----SSSRERSRSRGSKSRS-SS 260
Query: 784 RKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEE 843
R H+G P +R + SS +R + S S D R +SP +
Sbjct: 261 RSHRGSSSPR--KRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPER-------- 310
Query: 844 DSGSEHSRSRSRSGRRHSSHRSSRR 868
R RS SG HS RSS +
Sbjct: 311 -------RHRSSSGSSHSGSRSSSK 328
Score = 54.3 bits (129), Expect = 9e-07
Identities = 78/329 (23%), Positives = 114/329 (34%), Gaps = 28/329 (8%)
Query: 569 CNPLYFDFKLSRNKDARTKGTEKPK------DIGSSSKDHLQGLDPGEPNKSKEVGGEKI 622
C + F + S N+ R K TE +IG + + +GL + K
Sbjct: 20 CGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNW 79
Query: 623 VRSSGGRM-DAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRH-KKKKK 680
R S M + P +E G G E ++E G+ +KKKK
Sbjct: 80 ARRSECNMCNTPKYAKL------EERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKK 133
Query: 681 HKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERG--PKPEPPGS 738
++ + + E+K S+ E ++ + K K +++ AD + E S
Sbjct: 134 YRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDS 193
Query: 739 GSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRR 798
RR R S RS S + S S + + SS +R
Sbjct: 194 NKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRS----SSRERS 249
Query: 799 AGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGR 858
SRSS RS S SS R S S S E + S S S S R R
Sbjct: 250 RSRGSKSRSSSRSHRGS--------SSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKR 301
Query: 859 RHSSHRSSRRSYSSSSDASSDQSCYSRQR 887
R S RR SSS + S S+++
Sbjct: 302 RTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 81.3 bits (199), Expect = 7e-15
Identities = 125/503 (24%), Positives = 178/503 (35%), Gaps = 102/503 (20%)
Query: 646 EPGGSHGSETEDTGR---SLPSKKERSGKSHRHK-----------KKKKHKK-------- 683
EPG + +D G P+ R + +R K KKKK KK
Sbjct: 124 EPGLEYAPFDDDDGPVDCDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRK 183
Query: 684 ------------SSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGP 731
SS ++K K+ + + +++SG + K+R + + K K ++ P
Sbjct: 184 KRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRP 243
Query: 732 KPEPPG--------------------SGSPAPPRRRRRAQDD-----SQRRS---LPAEE 763
E PG S S +P R + +D+ SQR S P+
Sbjct: 244 HTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPS 303
Query: 764 GSSG---KKDEGGGGSSSQDHGGRKHKGELP---PSSCQRRAGTKRSSRS---------- 807
G SG + GG G S HGGR P PSS R K ++ +
Sbjct: 304 GGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKES 363
Query: 808 -SHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSS 866
S RS PSS A ++ + + R R R S RS
Sbjct: 364 PSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSL 423
Query: 867 RRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHR---- 922
R+ SSS S + S+ + + R++ R+ + S + R
Sbjct: 424 SRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGP 483
Query: 923 -SKRHKYSSSDDDYSLSCSQSRSRSRSHTRE-RSRSRGRSRSSSCSRSRSK------RRS 974
K S S S S+S S+SRS + E R S RS S SR K R S
Sbjct: 484 EGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHS 543
Query: 975 RSTTAHSWQRSRSYSRDRSRSTRSPS-----QRSGSRKRSWGHESPEERHSG---RRDFI 1026
+ + +RSRSYS R R SPS + + +RKR + P S D+
Sbjct: 544 EAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYS 603
Query: 1027 RSKIYRSQSP---HYFRSGRGEG 1046
RS SP H S R G
Sbjct: 604 TRSHSRSPSPGHSHGSYSSRSHG 626
Score = 79.3 bits (194), Expect = 3e-14
Identities = 128/513 (24%), Positives = 180/513 (35%), Gaps = 98/513 (19%)
Query: 608 PGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPG-GSHGSETEDTG------- 659
P K K+ GG + R R+++ S + S L K++ H + D+G
Sbjct: 166 PPPKKKKKKKGGHRRSRKKR-RLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRH 224
Query: 660 RSLPSKKERSGK---------------SHRHKKKKKHKKS-----------SKHKRKHKA 693
RS SK +R K SHRH H S S+ KH+
Sbjct: 225 RSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRD 284
Query: 694 DTEEKSSKAESGEKS-------------------KKRKKRKRKKNKSSAPADSERGPKPE 734
+ + S+ SG +S ++ + + +P D P P
Sbjct: 285 EGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPR 344
Query: 735 PPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSS 794
+ A P R ++ RS P+ +G G+ GG+ + R+ + +S
Sbjct: 345 VRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGR---AAGGAGRRRRRRRRRRRSRSSAS 401
Query: 795 CQRRAGTKRSSRSSHR--SQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRS 852
RR G +R + R S+ S S D+ S R +P E E G R+
Sbjct: 402 APRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGR---GAPGPGPEPGSERGHGGHGKRA 458
Query: 853 RSRSGRRHSSHRS----SRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRS 908
+ R R + S + SS +S RS+S S S RSR KR
Sbjct: 459 KERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWS-SSRSPSKSRSRSAEKRP 517
Query: 909 HDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRS 968
H S RS K S D R+R E +R+R RSRS S R
Sbjct: 518 H---------SPSRSPSPKKPLSRD------KDGEGRARHSEAEATRARRRSRSYSPIRK 562
Query: 969 RSK------RRSRSTTAHSWQRSRSYSRDRSRSTRS-----PSQRSGSRKRSWGHE--SP 1015
R + R T+A +R Y R S+ S S RS SR S GH S
Sbjct: 563 RRRDSPSFMEPRRITSAR--KRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSY 620
Query: 1016 EERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPG 1048
R G R RS R+ SP Y E G
Sbjct: 621 SSRSHGTRSRTRSP-SRTPSPSYHSRSSSESGG 652
Score = 56.2 bits (134), Expect = 2e-07
Identities = 113/453 (24%), Positives = 146/453 (32%), Gaps = 87/453 (19%)
Query: 875 DASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDD 934
D SCY R Y +S S K+ HR R K +
Sbjct: 140 DCDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGG--------HRRSRKKRRLESEC 191
Query: 935 YSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTA------------HSW 982
S S R + +S + R R RS S SR + + RSRS+ H+
Sbjct: 192 SCGSSSPLRKKKKSVKKHR-----RDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTE 246
Query: 983 QRSRSYSRDRSRSTRSPSQRSG-SRKRSWGHESPEERHSGRR-DFIRSKIYRSQSPHYFR 1040
R R S S+ SPS S S RS SP+ R GR+ RS RS SP
Sbjct: 247 SPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSP---S 303
Query: 1041 SGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSR 1100
G G G +++ G G S A G GR SP DK S S
Sbjct: 304 GGSGWGSPQRNGGSGQRSGAHG----------GRPGSAH-SPPDKPS---------SPSP 343
Query: 1101 KVERKPSVSEEVQATPNKAGPKLKDPP--QGYFGPKLPPSLGNKPVLPLIGKLPATRKPN 1158
+V K + + K P + P QG G + G+ R+
Sbjct: 344 RVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGA----------GRRRRRRRRR 393
Query: 1159 KKCEESGLERGEEQEQSETEEGPPGSSDALFGHQFPSEE-----TTGPLLDPPPEESKSG 1213
++ S + P GSS +L + S+ GP +P E G
Sbjct: 394 RRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGG 453
Query: 1214 EATADHPVAPLGTPAHSDCYPGDPTISHNYLPDPSDGDTLESLDSSSQPGP----VESSL 1269
P PA + PG +H P E SS PGP SS
Sbjct: 454 HGKRAKERPPRARPASTSPSPG----AHGRRGGP------EGKSSSRSPGPHPRSWSSSR 503
Query: 1270 LP------IAPDLEHFPSYAPPSGDPSIESTDG 1296
P A H PS +P P DG
Sbjct: 504 SPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDG 536
Score = 55.8 bits (133), Expect = 3e-07
Identities = 95/425 (22%), Positives = 149/425 (35%), Gaps = 74/425 (17%)
Query: 792 PSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSR 851
P+SC R R R+ H S S+ H++S + E E S R
Sbjct: 144 PASCYRG---HRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLR 200
Query: 852 SRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDS 911
+ +S ++H RS S S C ++++ + KR H
Sbjct: 201 KKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKN--------------KEKKRPHTE 246
Query: 912 DDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGR---SRSSSCSRS 968
S RS RH S S SLS S SRS S + R GR S+ SS SRS
Sbjct: 247 ------SPGRRSHRHS-SGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRS 299
Query: 969 -------------RSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQR-----SGSRKRSW 1010
R+ + + AH + ++S S+ SP R + +
Sbjct: 300 PSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPAR 359
Query: 1011 GHESPEERH--------------SGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGD 1056
G ESP R +GRR R + RS+S RG + RG
Sbjct: 360 GKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRG- 418
Query: 1057 DSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATP 1116
S++ +S+ G+GRG+ G PE + ++ + +P + +P
Sbjct: 419 SSRSLSRARSSSDSGSGRGAPGP-GPEPGSERG-----HGGHGKRAKERPPRARPASTSP 472
Query: 1117 NKAGPKLKDPPQGYFGPKLPPSLGNKPVLPLIGKLPATRKPNKKCEESGLERGEEQEQSE 1176
+ + P+G + P P ++R P+K S +R +S
Sbjct: 473 SPGAHGRRGGPEGKSSSRSPG--------PHPRSWSSSRSPSKSRSRSAEKRPHSPSRSP 524
Query: 1177 TEEGP 1181
+ + P
Sbjct: 525 SPKKP 529
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 80.5 bits (197), Expect = 1e-14
Identities = 143/720 (19%), Positives = 248/720 (34%), Gaps = 108/720 (15%)
Query: 462 SEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATP 521
S+ PK S + S K A+ + DQ S ++N SK+
Sbjct: 216 SKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNS-----------KTNQSKK------ 258
Query: 522 AGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRN 581
+GP+ P+ P P + +D + ++ + + + E + DF+ R
Sbjct: 259 ------KGPRTPSPP--PPIPEDIALGKKYKEKYKVKDRIEEK-TRDGKDRGRDFERQRE 309
Query: 582 KDARTKGTEKPKDIGS--SSKDHLQGLDPGEP----------NKSKEVGGEKIVRSSGGR 629
K + + T S SS+ H G ++ ++ + R
Sbjct: 310 KRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRR 369
Query: 630 MDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSH--RHKK------KKKH 681
+P + S +++ H S + GR ER+ +SH RH++ K+
Sbjct: 370 SASPYPSHSLSSPQRKQSPPRHRSPMREKGRH---DHERTSQSHDRRHERREDTRGKRDR 426
Query: 682 KKSSKHKRKHKADTEEKSSKAESGEKSKKRKKR-------KRKKNKSSAPADSE--RGPK 732
+K S+ +R+++ D + E R +R +R+ S DS R
Sbjct: 427 EKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYS 486
Query: 733 PEPPGSGSPAPPRRRRRAQD-------DSQRR--SLPAEEGSSGK------------KDE 771
+ S P R R A D D+ R+ + P E S G+ ++E
Sbjct: 487 RDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNE 546
Query: 772 GGGGSSSQDHGGR--KHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLH 829
S S+ R + +G +P + G++ S SH S S+ + + SS+
Sbjct: 547 SRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSN-SNYHDSWETRSSYPER 605
Query: 830 QKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSR--RSYSSSSDASSDQSCYSRQR 887
+ P + + ++ + S R R R R S R + + D+ R+
Sbjct: 606 DRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDE----RRE 661
Query: 888 SYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSR 947
D D D R R + D + R + + + + + R R +
Sbjct: 662 ERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREK 721
Query: 948 SHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRK 1007
RER R R R R R + + R +R R R+R R +R+ R
Sbjct: 722 ERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERD 781
Query: 1008 RSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKK---DDGRGDDSKAT--- 1061
+ + E RD R K + R G E KK ++G ++
Sbjct: 782 KERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRR 841
Query: 1062 ---GPPSQNSNIGTGRGSEGD-----CSPEDKNSVTAKLLLE------KIQSRKVERKPS 1107
P S N G + + P++ S++ L E K + RK ERK S
Sbjct: 842 REHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKES 901
Score = 73.6 bits (179), Expect = 1e-12
Identities = 134/704 (19%), Positives = 240/704 (34%), Gaps = 73/704 (10%)
Query: 575 DFKLSRNKDARTKGTEKPKDIGSSSKDHLQG------LDPGEPNKSK-EVGGEKIVRSSG 627
D++ +D K P++ S ++HL+ + N+S+ E+ +++ RS G
Sbjct: 506 DYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRG 565
Query: 628 GRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKS--S 685
+ P GS S Q S S D+ + S ER R + + S
Sbjct: 566 RVPELPEKGSRGSR-GSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFER 624
Query: 686 KHKRKHKADTEEKSSKAESGEKSKKR----KKRKRKKNKSSAPADSERGPKPEPPGSGSP 741
+H + + D E+ + S + + R ++ +R++ + D R +
Sbjct: 625 RHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDER--------- 675
Query: 742 APPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGT 801
A R R R +D + R E +K+ +++ + K E + R
Sbjct: 676 ARERDRERERDRERERERERERDREREKERELERERAREREREREK-ERDRERDRDRDHD 734
Query: 802 KRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHS 861
+ R R + + + ++ R ++ + E E E + R R R
Sbjct: 735 RERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKD 794
Query: 862 SHRSSRRSYSSS-----SDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDY 916
R RR + S++R ++ S S RR R H D Y
Sbjct: 795 KGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRR---REHSPDSDAY 851
Query: 917 ASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRS 976
S ++++H+ S + +SRS S SH E + R + R S RR
Sbjct: 852 NSGDDKNEKHRLLSQ----VVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEE 907
Query: 977 TTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRR--DFIRSKIYRSQ 1034
S R+++ S R+ + GH E+R + R D + K +
Sbjct: 908 QELKEKVSSVDKQREQTEILESSRMRA---QDIIGHHQSEDRETSDRAHDENKKKAKIQK 964
Query: 1035 SPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLL 1094
P KK+D G + NI T SP K K +
Sbjct: 965 KPI---------KKKKEDDVG---------IERGNIETTSEDGQVFSP--KKGQKKKSIE 1004
Query: 1095 EKIQSRKVERKPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLGNKPVLPLIGKLPAT 1154
+K + K + S E Q + K GP+ PP + ++ +
Sbjct: 1005 KKRKKSKGDSDISDEEAAQQSKKKR------------GPRTPPITTKEELVEMCNGKNGI 1052
Query: 1155 RKPNKKCEESGLERGEEQEQSETEEGPPGSSDALFGHQFPSEETTGPLLDPPPEESKSGE 1214
+ ++K E++ +++ + E A + LL PPP + +
Sbjct: 1053 LEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATATA 1112
Query: 1215 ATADHPVAPLGTPAHSDCYPGDPTISHNYLPDPSDGDTLESLDS 1258
T +A A + TIS + P + +T + DS
Sbjct: 1113 TTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDS 1156
Score = 60.8 bits (146), Expect = 9e-09
Identities = 92/419 (21%), Positives = 155/419 (36%), Gaps = 34/419 (8%)
Query: 640 SGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKS 699
S + Q+ G H SE +T + ++ K + KKK K+ + +T +
Sbjct: 930 SRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKK-KEDDVGIERGNIETTSED 988
Query: 700 SKAESGEKSKKRK--KRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRR 757
+ S +K +K+K ++KRKK+K + E + G PP + +
Sbjct: 989 GQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNG 1048
Query: 758 SLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQP---S 814
E S K+D S +D R E ++ G+ S SS P +
Sbjct: 1049 KNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVA 1108
Query: 815 SGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSS 874
+ + A+ + + +S + + + + + + SHR R+
Sbjct: 1109 TATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKV 1168
Query: 875 DA-----SSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRS--KRHK 927
+ Q + S S+ S+RS + S+DS + S +S KR
Sbjct: 1169 ETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVL 1228
Query: 928 YSSSDD---DYSLSCSQSR------------SRSRSHTRERSRSRGRSRSSSCSRSRSKR 972
+S S D SL + R SRS S R+ SRS RSS S R
Sbjct: 1229 HSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSS----PESDR 1284
Query: 973 RSRSTTAHSWQRSRSYSRDRSRSTRS-PSQRSGSRKRSWGHESPEERHSGR-RDFIRSK 1029
+ S + R R RDR R +R +R+R W ++ ++ R RD +R +
Sbjct: 1285 QVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRER 1343
Score = 58.9 bits (141), Expect = 4e-08
Identities = 98/460 (21%), Positives = 161/460 (35%), Gaps = 60/460 (13%)
Query: 643 NKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKK-HKKSSKHKRKHKADTEEKSSK 701
NK++ + + S P +KE S HR K+ K K+ + + + E
Sbjct: 91 NKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTPESEEENVEWETNRDD 150
Query: 702 AESGEKS----------KKRKKRKRKKNKSSAPADSERGP-----KPEPPGSGSPAPPRR 746
+++G+ + KR+K +R+ K +R + P S P
Sbjct: 151 SDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSP 210
Query: 747 RRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSR 806
R S +R + S+ KKD SS P QR + T +S +
Sbjct: 211 SLRKSSKSPKRKSSPKSSSASKKDRKTSAVSS------------PLLDQQRNSKTNQSKK 258
Query: 807 SSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRS- 865
R+ PS +D + + +++ EE+ G + R R + RS
Sbjct: 259 KGPRT-PSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRST 317
Query: 866 ----------SRRSYSSSSDASSDQSCYS----RQRSYSDDSYSDYSDRSRR----HSKR 907
S R +SSSS + S +S R+R+ S + RR +
Sbjct: 318 SPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSH 377
Query: 908 SHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHT-----RERSRSRGRSRS 962
S S + +HRS + D + + R R T RE+ R
Sbjct: 378 SLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYE 437
Query: 963 SSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGR 1022
S SR R R +R +RDR S R R + ++ E R
Sbjct: 438 QDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDP-- 495
Query: 1023 RDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATG 1062
RD RS ++ H +R G +K+D ++S++ G
Sbjct: 496 RD-SRS----TRDAHDYRDREGRDTHRKEDTYPEESRSYG 530
Score = 57.0 bits (136), Expect = 1e-07
Identities = 99/449 (22%), Positives = 149/449 (33%), Gaps = 44/449 (9%)
Query: 608 PGEPNKSKEVGGEK---IVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPS 664
P + K +VG E+ S G++ +P G + K+ S+ D + S
Sbjct: 966 PIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQS 1025
Query: 665 KKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAP 724
KK+R ++ K++ + K D+++K A S + R
Sbjct: 1026 KKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTA 1085
Query: 725 ADSERGPKPEPPGSGSPAPP--------------RRRRRAQDDSQRRSLPAEEGSSGKKD 770
+ G P P S P PP A S S S+ +
Sbjct: 1086 TATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTN 1145
Query: 771 EGGGGSSSQD-----HGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASS 825
+++D H R K E P + + R RS + + +S
Sbjct: 1146 TTNNTFANEDSHRKCHRTRVEKVETPHVTIED--AQHRKPMDQKRSSSLGSNRSNRSHTS 1203
Query: 826 HRLHQKSPSQYSEEEEEEDSGSE----HSRSRSR--------SGRRHSSHRSSRRSYSSS 873
RL +SPS S +D HS SR R +G R S +R S
Sbjct: 1204 GRL--RSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSR 1261
Query: 874 SDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDD 933
S +S Q RS+S S SDR S DS D ++ R + D
Sbjct: 1262 STSSDRQD----SRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRD 1317
Query: 934 DYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRS-TTAHSWQRSRSYSRDR 992
+ + R+R R R R R + R R R + S +R R RDR
Sbjct: 1318 TRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDR 1377
Query: 993 S-RSTRSPSQRSGSRKRSWGHESPEERHS 1020
+ S++ S + K HE E S
Sbjct: 1378 TFESSQIESVKRCEAKLEGEHERDLESTS 1406
Score = 49.3 bits (116), Expect = 3e-05
Identities = 158/863 (18%), Positives = 297/863 (34%), Gaps = 115/863 (13%)
Query: 83 RMEMELDYAEDAT-ERRRVLEVEKEDTEELRQKYKDYVDKEKAIAKALEDLRANFYCELC 141
R E +D +D ER R + E+E E ++ + D+E+ + LE RA
Sbjct: 660 REERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERERER 719
Query: 142 DKQYQKHQEFDNHINSYDHAHKQRLKDLKQREFARNVSSRSRKDEKKQEKALRRLHELAE 201
+K+ + ++ D + ++R ++ K+RE R R R+ E+++E+ R E A
Sbjct: 720 EKERDRERDRDRDHDRERERERERDRE-KEREREREERERERERERERERERERERERAR 778
Query: 202 QRKQAECAPGSGPMFKPTTVAVDEEGGEDDKDESATNSGTGATASCGLGSEFS----TDK 257
+R + + D++ G DD+ E G S ++
Sbjct: 779 ERDKER---------ERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNE 829
Query: 258 GGPFTAVQITNTTGLAQAPGLASQGISFGIKNNLGTPLQKLGVSFSFAKKAPVKLESIAS 317
G P + + G K+ L + + + P + S++
Sbjct: 830 GSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVR-----------PQESRSLSP 878
Query: 318 VFKDHAEEGT-SEDGTKPDEKSSDQGLQKVGDSDGSSNLDGKKEDEDPQDGGSLASTLSK 376
+G E+ KP+ K S + ++ + S++D ++E + + +
Sbjct: 879 SHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTE----------ILE 928
Query: 377 LKRMKREEGAGATEPEYYHYIPPAH--CKVKPNFPFLLFMRASEQMDGDNTTHPKNAPES 434
RM+ ++ G + E AH K K + E G + + E
Sbjct: 929 SSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSED 988
Query: 435 KKGSSP----KPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEP-------------- 476
+ SP K KS K + +S+ + P P
Sbjct: 989 GQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNG 1048
Query: 477 --GSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPT 534
G +++K SD S E + T+ E ++ T +TP+ S P P
Sbjct: 1049 KNGILEDSQKKEDTAFSDWSDEDVPDRTEVTE-AEHTATATTPGSTPSPLSSLLPPPPPV 1107
Query: 535 GPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTK----GTE 590
+ + A + F+ + +IS S P N+D+ K E
Sbjct: 1108 AT-ATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVE 1166
Query: 591 KPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRS-SGGRMDAPASGSACSGLNKQ---- 645
K + + +D Q P + +S +G + RS + GR+ +P++ SA + Q
Sbjct: 1167 KVETPHVTIED-AQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRK 1225
Query: 646 ----------------EPGGSHGSETEDTGRSLPSKKERS----GKSHRHKKKKKHKKSS 685
E G S + R PS+ S +SH ++
Sbjct: 1226 RVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQ 1285
Query: 686 KHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPR 745
H R D+ ++ + + E ++R++ +R + D+++ + P + R
Sbjct: 1286 VHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADK----DWPRNRDRDRLR 1341
Query: 746 RRRRAQDDSQRRSLPAEE--------GSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQR 797
R R ++ +RR L E +D SSQ ++ + +L +
Sbjct: 1342 ERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERD 1401
Query: 798 RAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSG 857
T R S + + + D D S + + S+ +E E D S+
Sbjct: 1402 LESTSRDSLALDKER-----MDKDLGSVQGFEETNKSERTESLEAGD-------DESKLD 1449
Query: 858 RRHSSHRSSRRSYSSSSDASSDQ 880
HS + Y SD D+
Sbjct: 1450 DAHSLGSGAGEGYEPISDDELDE 1472
Score = 46.2 bits (108), Expect = 2e-04
Identities = 96/417 (23%), Positives = 154/417 (36%), Gaps = 49/417 (11%)
Query: 684 SSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAP 743
SS ++R + T + + ++ + + +KR +SS+P E
Sbjct: 71 SSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESS------------- 117
Query: 744 PRRRRRAQDD---SQRRSLPAEEGS---SGKKDEGGGGSSSQDHGGRKHKGELPPSSCQR 797
R R R ++D ++ R+ +EE + +D+ G + D+ + E+ QR
Sbjct: 118 -RGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDY-VHELSLEMKRQKIQR 175
Query: 798 RAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSG 857
R + E S + +L SPS + + S S S S+
Sbjct: 176 ELMKLEQENMEKREEIIIKKEVSPEVVRSKL-SPSPSLRKSSKSPKRKSSPKSSSASKKD 234
Query: 858 RRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSD------YSDRSR---RHSKRS 908
R+ S+ S +S + + R S D Y ++ + R +++
Sbjct: 235 RKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKT 294
Query: 909 HDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRS 968
D D + R KR K S+ S SR H+ S +S SS S
Sbjct: 295 RDGKDRGRDFERQREKRDKPRSTS---PAGQHHSPISSRHHS-----SSSQSGSSIQRHS 346
Query: 969 RSKRRSRSTTAHSWQRSRSYSRDRSRST-RSPSQRSGSRKRSWGHESPEERHSGRRDFIR 1027
S RR R T + S+QR+ + RS S S S S RK+S R GR D R
Sbjct: 347 PSPRRKR-TPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHER 405
Query: 1028 SKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPED 1084
+ SQS R + GK+D R DS+ Q+ + + R D P D
Sbjct: 406 T----SQSHDRRHERREDTRGKRD--REKDSREEREYEQDQS--SSRDHRDDREPRD 454
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 79.7 bits (195), Expect = 2e-14
Identities = 67/187 (35%), Positives = 88/187 (47%), Gaps = 28/187 (14%)
Query: 855 RSGRRHSSH-RSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDD 913
+ GRRH S +SS++ S + S R+R S ++ D R R S R
Sbjct: 9 KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS--- 65
Query: 914 SDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRR 973
++ S+ R +RH+ S S+ R +SRS +RER +SR RSR SRSRS+ R
Sbjct: 66 --HSRSRSRERRHR----------SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER 113
Query: 974 SRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRS 1033
R + S RSR R RSRS RS SR R E P R F RS + R+
Sbjct: 114 KRRIRSRSRSRSRHRHRTRSRS----RTRSRSRDRKKRIEKP-------RRFSRS-LSRT 161
Query: 1034 QSPHYFR 1040
SP FR
Sbjct: 162 PSPPPFR 168
Score = 68.2 bits (165), Expect = 6e-11
Identities = 66/223 (29%), Positives = 93/223 (41%), Gaps = 41/223 (18%)
Query: 797 RRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRS 856
RR +K S H+S+ + E S D RL+ SE E+ E SR
Sbjct: 12 RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNS------SENGEDRHKRKERKSSR--- 62
Query: 857 GRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDY 916
GR HS RS R + S SR+R S RSR ++ S +
Sbjct: 63 GRSHSRSRSRERRHRSR----------SRERKKS---------RSRSRERKKSRSRSRER 103
Query: 917 ASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRS 976
S+ RS+ K + RSRSRS +R R R+R RSR+ S SR R KR +
Sbjct: 104 KKSRSRSRERK------------RRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKP 151
Query: 977 TT-AHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEER 1018
+ S R+ S R R+T +Q + +R+ + E+R
Sbjct: 152 RRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQR 194
Score = 48.1 bits (113), Expect = 6e-05
Identities = 40/187 (21%), Positives = 73/187 (39%), Gaps = 25/187 (13%)
Query: 574 FDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAP 633
F K R +++ K ++K K + K+H S + G E++ S G
Sbjct: 6 FFLKQGRRHESKDKSSKKHKSEEHNDKEH-----------SSDKGRERLNSSENGEDRHK 54
Query: 634 ASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKA 693
K G SH R +ER R +++KK + S+ ++K ++
Sbjct: 55 RKE------RKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRS 108
Query: 694 DTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPG------SGSPAPP--R 745
+ E+ + S +S+ R + + + + +R + E P S +P+PP R
Sbjct: 109 RSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFR 168
Query: 746 RRRRAQD 752
R A D
Sbjct: 169 GRNTAMD 175
Score = 44.7 bits (104), Expect = 7e-04
Identities = 40/132 (30%), Positives = 57/132 (43%), Gaps = 8/132 (6%)
Query: 746 RRRRAQDDSQRRSLPAEEGSSG-KKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRS 804
RR ++D S ++ E D+G +S ++G +HK + SS R RS
Sbjct: 12 RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
Query: 805 SRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSR---SRSRSGRRHS 861
HRS+ E S R +KS S+ E ++ E R SRSRS RH
Sbjct: 72 RERRHRSRSR---ERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRH- 127
Query: 862 SHRSSRRSYSSS 873
HR+ RS + S
Sbjct: 128 RHRTRSRSRTRS 139
Score = 40.4 bits (93), Expect = 0.013
Identities = 46/237 (19%), Positives = 80/237 (33%), Gaps = 37/237 (15%)
Query: 769 KDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRL 828
KD+ S++H ++H + + R + + H+ + + S
Sbjct: 17 KDKSSKKHKSEEHNDKEHSSD----KGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 72
Query: 829 HQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRS 888
++ S+ E ++ E +SRSRS R S SR + SR RS
Sbjct: 73 ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR---------ERKRRIRSRSRS 123
Query: 889 YSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRS 948
S RH RS S S+ R KR + + SRS S
Sbjct: 124 RS----------RHRHRTRSRSRTRS---RSRDRKKR-----------IEKPRRFSRSLS 159
Query: 949 HTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGS 1005
T RGR+ + + ++R R+ + + + + + + GS
Sbjct: 160 RTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGS 216
Score = 37.4 bits (85), Expect = 0.11
Identities = 51/211 (24%), Positives = 88/211 (41%), Gaps = 41/211 (19%)
Query: 643 NKQEPGGSHGSETE-DTGRSLPSKKER--SGKSHRHKKKKKHKKSSKHKRKHKADTEEKS 699
+K + H SE D S +ER S ++ + K+K +KSS+ + ++ + E+
Sbjct: 16 SKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERR 75
Query: 700 SKAESGEKSKKR---KKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQR 756
++ S E+ K R ++RK+ +++S S + R+RR + S+
Sbjct: 76 HRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR------------ERKRRIRSRSRS 123
Query: 757 RSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRS---QP 813
RS S + S S+D RK + E P +R SRS R+ P
Sbjct: 124 RSRHRHRTRSRSRTR----SRSRD---RKKRIEKP----------RRFSRSLSRTPSPPP 166
Query: 814 SSGDE---DSDDASSHRLHQKSPSQYSEEEE 841
G D+ +A + RL + Q E+E
Sbjct: 167 FRGRNTAMDAQEALARRLERAKKLQEQREKE 197
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 79.3 bits (194), Expect = 3e-14
Identities = 166/746 (22%), Positives = 273/746 (36%), Gaps = 124/746 (16%)
Query: 333 KPDEKSSDQGLQKVGDSDGSSNLDGKKEDEDPQDGGSLASTLSKLKRMKREEGAG----- 387
K D+G +K S S+ D KK + +S +SK KR + E +
Sbjct: 730 KTQAGKDDKGKRKRKSSTSGSDFDTKKGKS------AKSSIISKKKRQTQSESSNYDSEL 783
Query: 388 ATEPEYYHYIPPAHCKVKPNFPFLLFMRASE-----QMDGDNTTHPKNAPESKKGSSPKP 442
E + I A K P +SE + DN H KN S++GSS
Sbjct: 784 EKEIKSMSKIGAART-TKKRIPNTKDFDSSEDEKHSKKGMDNQGH-KNLKTSQEGSSDDA 841
Query: 443 KSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLESHSQKV 502
+ + AE TV K+T++ E + K + A V S + S
Sbjct: 842 ERKQERETFSSAEGTVD------KDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTS 895
Query: 503 SETQMCESNSSKETSLATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAE 562
E + K L T K+ Q+G F L KD+S + +++
Sbjct: 896 LEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKF---LKKDQSDETSEDDK----KQSK 948
Query: 563 PSISYSCNPLYFD---FKLSRNKDARTKGTEK----------PKDIGSSSKDHLQGLDPG 609
P F K+ + ++ + GTEK PK I K G G
Sbjct: 949 KGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGI----KQIKNGTTDG 1004
Query: 610 EPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERS 669
E K +R + S A K G +ED KK ++
Sbjct: 1005 EKKSKK-------IRDKTSKKKDELSDYAEKSTGK----GDSCDSSED-------KKSKN 1046
Query: 670 GKSHRHKKKKKHKKSSKHKRKH--KADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADS 727
G R KK+ K S KR+ +DTE+ S K + S KR KR + + + S
Sbjct: 1047 GAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL--SS 1104
Query: 728 ERGPKPEPPGSGSP-----APPRRRRRAQDDSQRRSLPAEEG-------SSGKKDEGGGG 775
+R K GS S + ++++ + S+++++ +E S+ +K
Sbjct: 1105 KRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITS 1164
Query: 776 SSSQD--HGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQ-PSSGDEDSDDASSHRLHQKS 832
SSS D + GE + + T+ SSH SSGDE L +
Sbjct: 1165 SSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDE--------ALSKSV 1216
Query: 833 PSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSD---QSCYSRQRSY 889
P +++++ D + ++ + + SS D SSD + R
Sbjct: 1217 PVTVDDDDDDNDPENRIAKKMLLE--------EIKANLSSDEDGSSDDEPEEGKKRTGKQ 1268
Query: 890 SDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSH 949
++++ D +++ +S+ DS++S +HR RHK + SD + S + +++ + H
Sbjct: 1269 NEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGE---SGEEKKTKPKEH 1325
Query: 950 TRERSRSR----------------GRSRSSSCSRSRSKRRSRSTT-AHSWQRSRSYSRDR 992
+ R+R G S S S + R+RS A + RSY + +
Sbjct: 1326 KEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKK 1385
Query: 993 SRSTRSPSQRSGSRKRSWGHESPEER 1018
R + S S +S E EE+
Sbjct: 1386 KRRRIKVQEDSSSENKSNSEEEEEEK 1411
Score = 63.9 bits (154), Expect = 1e-09
Identities = 158/811 (19%), Positives = 273/811 (33%), Gaps = 141/811 (17%)
Query: 226 EGGEDDKDESATNSGTGATASCGLGSEFSTDKGGPFTAVQITNTTGLAQAPGLASQGISF 285
+ G+DDK + S T GS+F T KG + I+ Q+ S
Sbjct: 732 QAGKDDKGKRKRKSSTS-------GSDFDTKKGKSAKSSIISKKKRQTQSE---SSNYDS 781
Query: 286 GIKNNLGTPLQKLGVSFSFAKKAPVKLESIASVFKDHAEEGTSEDGTK----PDEKSSDQ 341
++ + + + K+G + + K+ P + +S + H+++G G K E SSD
Sbjct: 782 ELEKEIKS-MSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDD 840
Query: 342 GLQK-----VGDSDGSSNLDG---KKEDEDPQDGGSLASTLSKLKRMKREEGAGATE--- 390
+K ++G+ + D + D P+ + AST K +E+ + E
Sbjct: 841 AERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRK 900
Query: 391 ----PEYYHYIPPAHCK-----VKPNFPFLLFMRASEQMDGDNTTHPKNAPESKKGSSPK 441
E ++ CK + L S++ D+ K E KK S
Sbjct: 901 VAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDF 960
Query: 442 PKSCIKA-----AASQGAEKTVS--EVSEQPKETSMTEPSEPGSKAEAKKALGGDVSDQS 494
K IK ++S G EK E+ PK + + ++KK + D++
Sbjct: 961 KKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKK-----IRDKT 1015
Query: 495 LESHSQKVSE-TQMCESNSSKETSLATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPS 553
S+K E + E ++ K S + K+S+ G +L K S
Sbjct: 1016 ----SKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSS 1071
Query: 554 ELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNK 613
+ S + +L ++ +K K GSSS D + + + K
Sbjct: 1072 SDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKK 1131
Query: 614 SKEVGGEKIV----------RSSGGRMDAPASGSACSGLNKQEPGG-SHGSETED----- 657
+ +K V R+S R A + S+ S + + GS E
Sbjct: 1132 QRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPV 1191
Query: 658 ---------TGRSLPSKKERSGKS----------HRHKKKKKHKKSSKHKRKHKADTEEK 698
TG S E KS + + KK + K ++E
Sbjct: 1192 TENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDED 1251
Query: 699 SSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRS 758
S + E+ KKR ++ ++N A ++ + + S P R R R
Sbjct: 1252 GSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLL-----RHK 1306
Query: 759 LPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDE 818
L +G SG+ +++ K R++ E
Sbjct: 1307 LTVSDGESGE---------------------------EKKTKPKEHKEVKGRNRRKVSSE 1339
Query: 819 DSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGR--------RHSSHRSSRRSY 870
DS+D S Q S EE + R R+RS + R + RR
Sbjct: 1340 DSED---------SDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRI 1390
Query: 871 SSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSS 930
D+SS+ S + ++ + + + D +D + K R K K
Sbjct: 1391 KVQEDSSSENKSNSEE---EEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILK 1447
Query: 931 SDDDYSLSCSQSRSRSRSHTRERSRSRGRSR 961
DD + +Q+ + R+R R R R
Sbjct: 1448 --DDKLRTETQNALKEEEERRKRIAERERER 1476
Score = 55.8 bits (133), Expect = 3e-07
Identities = 96/470 (20%), Positives = 179/470 (38%), Gaps = 42/470 (8%)
Query: 649 GSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKS-SKAESGEK 707
G ++ +G +KK +S KS KKK+ +S + + E KS SK +
Sbjct: 739 GKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAART 798
Query: 708 SKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRR-SLPAEEGSS 766
+KKR + + S + E+ K G + + DD++R+ +
Sbjct: 799 TKKRIPNTKDFDSS----EDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAE 854
Query: 767 GKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSH 826
G D+ +D +K + + +G ++S S + + E S +
Sbjct: 855 GTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTK 914
Query: 827 --RLHQKSPSQYSE---EEEEEDSGSEHSRSRSRSGRRHSSHRSS--------RRSYSSS 873
+ Q S +E ++++ D SE + +S+ G S + Y SS
Sbjct: 915 TCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESS 974
Query: 874 SDASS-----DQSC-YSRQRSYSDDSYSDYSDRSRR-HSKRSHDSDD-SDYASSKHRSKR 925
SD + ++ C + + + +D +S++ K S D+ SDYA K K
Sbjct: 975 SDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYA-EKSTGKG 1033
Query: 926 HKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRR-------SRSTT 978
SS+D S + + R + R +S + + SSS + S + R
Sbjct: 1034 DSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKR 1093
Query: 979 AHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHY 1038
+R S+ ++ +S S S + + S ++ ++R S ++ ++ I + + +
Sbjct: 1094 IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKK---KAVIVKEKKRNS 1150
Query: 1039 FRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSV 1088
R+ K+ D S QNS IG G E P +N V
Sbjct: 1151 LRTSTKR---KQADITSSSSSDIEDDDQNS-IGEGSSDEQKIKPVTENLV 1196
Score = 48.5 bits (114), Expect = 5e-05
Identities = 132/663 (19%), Positives = 221/663 (33%), Gaps = 103/663 (15%)
Query: 577 KLSRNKDARTKGTEKPKDIGSSSKDH--LQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPA 634
++ KD + EK G ++ H L+ G + ++ + S+ G +D
Sbjct: 802 RIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVD--- 858
Query: 635 SGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHK-- 692
+ L + P S + D G S KE+S S +K + K+ SKH +
Sbjct: 859 KDTTIMELRDRLPKKQQASASTD-GVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCK 917
Query: 693 ------ADTEEKSSKAESGEKSKKRKKRKRKKN--KSSAPADSERG-----PKPEPPGSG 739
+D EK K + +++ + K++ KK + P+D ++ + E G
Sbjct: 918 KVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDG 977
Query: 740 SPAPPRRR------------RRAQDDSQRRSLPAEEGSSGKKDE-----------GGGGS 776
+ P R + D +++S + +S KKDE G
Sbjct: 978 TEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCD 1037
Query: 777 SSQDHGGRKHKGELPPSSCQR--RAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPS 834
SS+D + C+ ++ KR SS ++ S ED ++S RL
Sbjct: 1038 SSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRL------ 1091
Query: 835 QYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSR--RSYSSSSDA--SSDQSCYSRQRSYS 890
R R R SS R+++ +S SSSSDA SS+ + +QR+ S
Sbjct: 1092 ---------------KRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSS 1136
Query: 891 DDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRS-----KRHKYSSSDDDYSLSCSQSRSR 945
++ R + S +D SS + S D+ +
Sbjct: 1137 KKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLV 1196
Query: 946 SRSHTRERSRSRGRSRSSSC---------SRSRSKRRSRSTTAHSWQRSRSYSRDRSRST 996
SHT S + S S R ++ + + S D S
Sbjct: 1197 LSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDD 1256
Query: 997 RSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGD 1056
+ + K++ + EE + S S+ P Y R DG
Sbjct: 1257 EPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRY-RHRLLRHKLTVSDGESG 1315
Query: 1057 DSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATP 1116
+ K T P G R ED + ++ VSEEV +
Sbjct: 1316 EEKKTKPKEHKEVKGRNRRKVSSEDSEDSDF----------------QESGVSEEVSESE 1359
Query: 1117 NKAGPKLKDPPQGYFGPKLPPSLGNKPVLPLIGKLPATRKPNKKCEESGLERGEEQEQSE 1176
++ P+ + + S K I + NK E E EE+E+ E
Sbjct: 1360 DEQRPRTRSAKKAELEEN-QRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEE 1418
Query: 1177 TEE 1179
EE
Sbjct: 1419 EEE 1421
Score = 43.5 bits (101), Expect = 0.002
Identities = 79/442 (17%), Positives = 159/442 (35%), Gaps = 44/442 (9%)
Query: 677 KKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRK---RKKNKSSAPADSERGPKP 733
++ K++ +R + + +S E E K+++K RKK+K ++ + PKP
Sbjct: 616 RRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKP 675
Query: 734 EPPGSGSPAPPRRRRRAQD---DSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGEL 790
+ P ++ D DS +E S ++ H K +L
Sbjct: 676 ------NKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDL 729
Query: 791 PPSSCQRRAGTKRSSRSSHRSQPSSGDEDS---DDASSHRLHQKSPSQYSEEEEEEDSGS 847
+ +AG + +S S D D+ A S + +K SE +
Sbjct: 730 -----KTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELE 784
Query: 848 EHSRSRSRSGRRHSSHR--SSRRSYSSSSDA---------SSDQSCYSRQRSYSDDSYSD 896
+ +S S+ G ++ + + + + SS D ++ + Q SDD+
Sbjct: 785 KEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERK 844
Query: 897 YSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRS 956
+ ++ + D D + K+ + S+S D + +S + R+ + +
Sbjct: 845 QERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAET 904
Query: 957 RGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESP- 1015
+ +S+ + + S A + + + S + S + S++ K+
Sbjct: 905 KEKSKHLKTKTCKKVQDGLSDIAEKFLK-KDQSDETSEDDKKQSKKGTEEKKKPSDFKKK 963
Query: 1016 ----EERHSGRRDFIRSKIYRSQSPHY------FRSGRGEGPGKKDDGRGDDSKATGPPS 1065
E+++ D R + H+ ++G +G K R SK S
Sbjct: 964 VIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELS 1023
Query: 1066 QNSNIGTGRGSEGDCSPEDKNS 1087
+ TG+G D S EDK S
Sbjct: 1024 DYAEKSTGKGDSCD-SSEDKKS 1044
Score = 40.8 bits (94), Expect = 0.010
Identities = 44/243 (18%), Positives = 84/243 (34%), Gaps = 30/243 (12%)
Query: 627 GGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSK 686
G D P G +G +E G ++ + S +E +RH+ +
Sbjct: 1252 GSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLR------- 1304
Query: 687 HKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRR 746
HK + S E K K+ K+ K + + + DSE E S +
Sbjct: 1305 ----HKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESED 1360
Query: 747 RRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSR 806
+R + S +++ E S K+ + Q+ ++K S+ + K
Sbjct: 1361 EQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENK-----SNSEEEEEEKEEEE 1415
Query: 807 SSHRSQPSSGDEDSDDASS--------------HRLHQKSPSQYSEEEEEEDSGSEHSRS 852
+ ++++DD+ S +L ++ + EEEE +E R
Sbjct: 1416 EEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERERE 1475
Query: 853 RSR 855
R +
Sbjct: 1476 REK 1478
Score = 37.7 bits (86), Expect = 0.084
Identities = 91/432 (21%), Positives = 150/432 (34%), Gaps = 80/432 (18%)
Query: 654 ETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKK 713
ET+ P E+ S K + + S+H ++ E++++K+ GE KK
Sbjct: 402 ETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGE----HKK 457
Query: 714 RKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGG 773
RK+ PA++ + S P +D + E SS D G
Sbjct: 458 SDRKEEPQYEPANTSEDLDMDIVSVPSSVP-------EDIFENLETAMEVQSS--VDHQG 508
Query: 774 GGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRS-------------SHRSQPSSG---D 817
GSS + +L SS R G K + + S + P G
Sbjct: 509 DGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQ 568
Query: 818 EDSDDASSHRLHQKSPSQYSEEEEEEDSGSEH----------SRSRSRSGRRHSSHRSSR 867
E D ++ +P +E+S +EH S R R + R
Sbjct: 569 EVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRR 628
Query: 868 RSYSSSSDASSDQSCYSR---------------QRSYSDDSYSDYSDRSRRHSKRSHDSD 912
+ ++ ++SD+ C +R+ SD + + SK+S D
Sbjct: 629 PTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVD 688
Query: 913 ---DSD--YASSKHRSKRHKYSSSDDD-----------YSLSCSQSRSRSRSHTRERSRS 956
DSD A K S+ SSSD D Y L + R+ S S
Sbjct: 689 QNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTS 748
Query: 957 -------RGRS-RSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKR 1008
+G+S +SS S+ + + +S S+ S S + + R+ +R + K
Sbjct: 749 GSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKD 808
Query: 1009 SWGHESPEERHS 1020
S +E+HS
Sbjct: 809 F--DSSEDEKHS 818
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.125 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,864,274
Number of Sequences: 37866
Number of extensions: 4140221
Number of successful extensions: 56431
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 587
Number of HSP's successfully gapped in prelim test: 1713
Number of HSP's that attempted gapping in prelim test: 25354
Number of HSP's gapped (non-prelim): 16350
length of query: 1502
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1387
effective length of database: 13,892,928
effective search space: 19269491136
effective search space used: 19269491136
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.