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Search of human proteins with 50897850
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50897850 KIAA1914 protein isoform 1 [Homo sapiens]
(818 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50897850 KIAA1914 protein isoform 1 [Homo sapiens] 1636 0.0
gi|24308338 KIAA1914 protein isoform 2 [Homo sapiens] 1623 0.0
gi|197382472 actin filament associated protein 1 isoform a [Homo... 448 e-126
gi|40807504 actin filament associated protein 1 [Homo sapiens] 349 5e-96
gi|226437595 actin filament associated protein 1-like 1 isoform ... 312 7e-85
gi|55742689 actin filament associated protein 1-like 1 isoform 1... 312 7e-85
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap... 54 4e-07
gi|88501740 TRIO and F-actin binding protein isoform 1 [Homo sap... 54 4e-07
gi|88501741 TRIO and F-actin binding protein isoform 2 [Homo sap... 50 8e-06
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 46 1e-04
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 46 1e-04
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 46 2e-04
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 45 2e-04
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 45 3e-04
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 43 0.001
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 43 0.001
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho... 43 0.001
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 43 0.001
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho... 43 0.001
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho... 43 0.001
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 43 0.001
gi|148746195 trichohyalin [Homo sapiens] 42 0.002
gi|11119430 testis-specific kinase substrate [Homo sapiens] 42 0.002
gi|38044112 restin isoform b [Homo sapiens] 42 0.002
gi|4506751 restin isoform a [Homo sapiens] 42 0.002
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 42 0.003
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 41 0.004
gi|50083279 centrosome protein 4 [Homo sapiens] 41 0.004
gi|55770834 centromere protein F [Homo sapiens] 41 0.004
gi|14589862 aspartate beta-hydroxylase isoform d [Homo sapiens] 41 0.005
>gi|50897850 KIAA1914 protein isoform 1 [Homo sapiens]
Length = 818
Score = 1636 bits (4237), Expect = 0.0
Identities = 818/818 (100%), Positives = 818/818 (100%)
Query: 1 MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKV 60
MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKV
Sbjct: 1 MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKV 60
Query: 61 TINKQQNAESQGKAPEEQGLLPNGEPSQHSSAPQKSLPDLPPPKMIPERKQLAIPKTESP 120
TINKQQNAESQGKAPEEQGLLPNGEPSQHSSAPQKSLPDLPPPKMIPERKQLAIPKTESP
Sbjct: 61 TINKQQNAESQGKAPEEQGLLPNGEPSQHSSAPQKSLPDLPPPKMIPERKQLAIPKTESP 120
Query: 121 EGYYEEAEPYDTSLNEDGEAVSSSYESYDEEDGSKGKSAPYQWPSPEAGIELMRDARICA 180
EGYYEEAEPYDTSLNEDGEAVSSSYESYDEEDGSKGKSAPYQWPSPEAGIELMRDARICA
Sbjct: 121 EGYYEEAEPYDTSLNEDGEAVSSSYESYDEEDGSKGKSAPYQWPSPEAGIELMRDARICA 180
Query: 181 FLWRKKWLGQWAKQLCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLK 240
FLWRKKWLGQWAKQLCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLK
Sbjct: 181 FLWRKKWLGQWAKQLCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLK 240
Query: 241 ITPMNADVIVLGLQSKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEK 300
ITPMNADVIVLGLQSKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEK
Sbjct: 241 ITPMNADVIVLGLQSKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEK 300
Query: 301 YLSASEYGSSVDGHPEVPETKDVKKKCSAGLKLSNLMNLGRKKSTSLEPVERSLETSSYL 360
YLSASEYGSSVDGHPEVPETKDVKKKCSAGLKLSNLMNLGRKKSTSLEPVERSLETSSYL
Sbjct: 301 YLSASEYGSSVDGHPEVPETKDVKKKCSAGLKLSNLMNLGRKKSTSLEPVERSLETSSYL 360
Query: 361 NVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSPDHLYSFRILHK 420
NVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSPDHLYSFRILHK
Sbjct: 361 NVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSPDHLYSFRILHK 420
Query: 421 GEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSLLLMQ 480
GEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSLLLMQ
Sbjct: 421 GEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSLLLMQ 480
Query: 481 RKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVADDPNERESDRVYLDL 540
RKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVADDPNERESDRVYLDL
Sbjct: 481 RKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVADDPNERESDRVYLDL 540
Query: 541 TPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLES 600
TPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLES
Sbjct: 541 TPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLES 600
Query: 601 LEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNR 660
LEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNR
Sbjct: 601 LEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNR 660
Query: 661 TEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEID 720
TEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEID
Sbjct: 661 TEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEID 720
Query: 721 EECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLENVSPRPKAVTPASAPD 780
EECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLENVSPRPKAVTPASAPD
Sbjct: 721 EECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLENVSPRPKAVTPASAPD 780
Query: 781 CTPVNSATTLKNRPLSVVVTGKGTVLQKAKEWEKKGAS 818
CTPVNSATTLKNRPLSVVVTGKGTVLQKAKEWEKKGAS
Sbjct: 781 CTPVNSATTLKNRPLSVVVTGKGTVLQKAKEWEKKGAS 818
>gi|24308338 KIAA1914 protein isoform 2 [Homo sapiens]
Length = 814
Score = 1623 bits (4202), Expect = 0.0
Identities = 814/818 (99%), Positives = 814/818 (99%), Gaps = 4/818 (0%)
Query: 1 MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKV 60
MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKV
Sbjct: 1 MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKV 60
Query: 61 TINKQQNAESQGKAPEEQGLLPNGEPSQHSSAPQKSLPDLPPPKMIPERKQLAIPKTESP 120
TINKQQNAESQGKAPEEQGLLPNGEPSQHSSAPQKSLPDLPPPKMIPERKQLAIPKTESP
Sbjct: 61 TINKQQNAESQGKAPEEQGLLPNGEPSQHSSAPQKSLPDLPPPKMIPERKQLAIPKTESP 120
Query: 121 EGYYEEAEPYDTSLNEDGEAVSSSYESYDEEDGSKGKSAPYQWPSPEAGIELMRDARICA 180
EGYYEEAEPYDTSLNEDGEAVSSSYESYDEEDGSKGKSAPYQWPSPEAGIELMRDARICA
Sbjct: 121 EGYYEEAEPYDTSLNEDGEAVSSSYESYDEEDGSKGKSAPYQWPSPEAGIELMRDARICA 180
Query: 181 FLWRKKWLGQWAKQLCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLK 240
FLWRKKWLGQWAKQLCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLK
Sbjct: 181 FLWRKKWLGQWAKQLCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLK 240
Query: 241 ITPMNADVIVLGLQSKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEK 300
ITPMNADVIVLGLQSKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEK
Sbjct: 241 ITPMNADVIVLGLQSKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEK 300
Query: 301 YLSASEYGSSVDGHPEVPETKDVKKKCSAGLKLSNLMNLGRKKSTSLEPVERSLETSSYL 360
YLSASEYGSSVDGHPEVPETKDVKKKCSAGLKLSNLMNLGRKKSTSLEPVERSLETSSYL
Sbjct: 301 YLSASEYGSSVDGHPEVPETKDVKKKCSAGLKLSNLMNLGRKKSTSLEPVERSLETSSYL 360
Query: 361 NVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSPDHLYSFRILHK 420
NVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSPDHLYSFRILHK
Sbjct: 361 NVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSPDHLYSFRILHK 420
Query: 421 GEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSLLLMQ 480
GEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSLLLMQ
Sbjct: 421 GEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSLLLMQ 480
Query: 481 RKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVADDPNERESDRVYLDL 540
RKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVADDPNERESDRVYLDL
Sbjct: 481 RKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVADDPNERESDRVYLDL 540
Query: 541 TPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLES 600
TPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLES
Sbjct: 541 TPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLES 600
Query: 601 LEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNR 660
LEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNR
Sbjct: 601 LEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNR 660
Query: 661 TEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEID 720
TEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEID
Sbjct: 661 TEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEID 720
Query: 721 EECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLENVSPRPKAVTPASAPD 780
EECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLEN PKAVTPASAPD
Sbjct: 721 EECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLEN----PKAVTPASAPD 776
Query: 781 CTPVNSATTLKNRPLSVVVTGKGTVLQKAKEWEKKGAS 818
CTPVNSATTLKNRPLSVVVTGKGTVLQKAKEWEKKGAS
Sbjct: 777 CTPVNSATTLKNRPLSVVVTGKGTVLQKAKEWEKKGAS 814
>gi|197382472 actin filament associated protein 1 isoform a [Homo
sapiens]
Length = 814
Score = 448 bits (1153), Expect = e-126
Identities = 322/867 (37%), Positives = 455/867 (52%), Gaps = 108/867 (12%)
Query: 7 LEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKVTINKQQ 66
+E+L+ EL FL++LD E L+ST KK+ + +L S D K KQ+
Sbjct: 1 MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDV------KDHAQKQE 54
Query: 67 NAESQGKAPEEQGLLPNGEPSQHSSAPQKSLPDLPPPKMIPERKQLAIPKTESPEGYYEE 126
A S LP + PQ LP++P P + P+ +P + PEGYYEE
Sbjct: 55 TANS----------LP--------APPQMPLPEIPQPWLPPDSGPPPLPTSSLPEGYYEE 96
Query: 127 AEP--------YDTSLNEDGEAVSSSYESYDEED-GSKGKSAPYQWPSPEAGIELMRDAR 177
A P Y TS N D +A+SSSYESYDEE+ KGK +QWPS EA ++L++DA+
Sbjct: 97 AVPLSPGKAPEYITS-NYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAK 155
Query: 178 ICAFLWRKKWLGQWAKQLCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEH 237
ICAFL RKK GQW K LCVIKD +LLCYKSSKD PQ+++ L G ++ + K +KK+H
Sbjct: 156 ICAFLLRKKRFGQWTKLLCVIKDTKLLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKH 215
Query: 238 KLKITPMNADVIVLGLQSKDQAEQWLRVIQEV-SGLPSEGASEGNQYTPDAQRFNCQKPD 296
+LKIT D +VL +QSK+QAEQWL+VI+E SG SE P K +
Sbjct: 216 ELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDSE----CPPPPSSPVHKAE 271
Query: 297 IAEKYLSASEYGSSVDGHPEVPET-----KDVKKKCSA------------GLKLSNLMNL 339
+ EK LS+ S +G E T + VK+K S+ G K++ +++L
Sbjct: 272 L-EKKLSSERPSSDGEGVVENGITTCNGKEQVKRKKSSKSEAKGTVSKVTGKKITKIISL 330
Query: 340 GRKKSTSLE---PVERSLETSSYLNVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPL 396
G+KK ++ E E + T YLNVL NS+W+ RWC V+DN L F++DR K +
Sbjct: 331 GKKKPSTDEQTSSAEEDVPTCGYLNVLSNSRWRERWCRVKDNKLIFHKDRTDLKTHIVSI 390
Query: 397 SLVGCEVVPDPSPDHLYSFRILHKGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFT 456
L GCEV+P H +FR+L G+E+A LEA SSE+MG W+G+LL+E+GS TDPE
Sbjct: 391 PLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALH 450
Query: 457 YDYVDADRVSCIVSAAKNSLLLMQRKFSEPNTYIDGLPSQDRQEE----LYDDVDLSELT 512
YDY+D + + ++ AK + M R+ N Y+ G + YDDV +
Sbjct: 451 YDYIDVEMSASVIQTAKQTFCFMNRRVISANPYLGGTSNGYAHPSGTALHYDDVPC--IN 508
Query: 513 AAVEPTEEATPVADDPNERE-----SDRVYLDLTPVKSFLHGPSSAQAQASSPTLSCLDN 567
+ EP E+ P + E + +Y +L P F S A +AS + L +
Sbjct: 509 GSWEP-EDGFPASCSRGLGEEVLYDNAGLYDNLPPPHIFAR-YSPADRKASRLSADKLSS 566
Query: 568 ATEALPADSGPGPTPDEPCIKCPENLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPPS 627
PA S T + L QL+ +P S +T + + +S P
Sbjct: 567 NHYKYPA-SAQSVTNTSSVGRASLGL-NSQLKGKKPPVASNGVT-----GKGKTLSSQPK 619
Query: 628 CPDAVVATPPGASPPVKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLA 687
D P A V R +A+ K GKNR EA+ KR ++E L K+KE +R LA
Sbjct: 620 KAD------PAA---VVKRTGSNAAQYKYGKNRVEADAKRLQTKEEELLKRKEALRNRLA 670
Query: 688 QLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKA 747
QLRKE+++L+ + ++ A LE+KLK+++EECR +E+ RV LEL + EVK++LKKA
Sbjct: 671 QLRKERKDLRAAIEVNAGRKPQAILEEKLKQLEEECRQKEAERVSLELELTEVKESLKKA 730
Query: 748 EAGPVTLGTTVD----TTHLENVSPRPKAVTPASAPDC--------TPVNSATTLKNRPL 795
AG VTLG ++ T+ ++ R + + + C PVNSA LK
Sbjct: 731 LAGGVTLGLAIEPKSGTSSPQSPVFRHRTLENSPISSCDTSDTEGPVPVNSAAVLKK--- 787
Query: 796 SVVVTG----KGTVLQKAKEWEKKGAS 818
S G +G VL+KAKEWE K +
Sbjct: 788 SQAAPGSSPCRGHVLRKAKEWELKNGT 814
>gi|40807504 actin filament associated protein 1 [Homo sapiens]
Length = 730
Score = 349 bits (896), Expect = 5e-96
Identities = 212/516 (41%), Positives = 293/516 (56%), Gaps = 60/516 (11%)
Query: 7 LEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKVTINKQQ 66
+E+L+ EL FL++LD E L+ST KK+ + +L S D K KQ+
Sbjct: 1 MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDV------KDHAQKQE 54
Query: 67 NAESQGKAPEEQGLLPNGEPSQHSSAPQKSLPDLPPPKMIPERKQLAIPKTESPEGYYEE 126
A S LP + PQ LP++P P + P+ +P + PEGYYEE
Sbjct: 55 TANS----------LP--------APPQMPLPEIPQPWLPPDSGPPPLPTSSLPEGYYEE 96
Query: 127 AEP--------YDTSLNEDGEAVSSSYESYDEED-GSKGKSAPYQWPSPEAGIELMRDAR 177
A P Y TS N D +A+SSSYESYDEE+ KGK +QWPS EA ++L++DA+
Sbjct: 97 AVPLSPGKAPEYITS-NYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAK 155
Query: 178 ICAFLWRKKWLGQWAKQLCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEH 237
ICAFL RKK GQW K LCVIKD +LLCYKSSKD PQ+++ L G ++ + K +KK+H
Sbjct: 156 ICAFLLRKKRFGQWTKLLCVIKDTKLLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKH 215
Query: 238 KLKITPMNADVIVLGLQSKDQAEQWLRVIQEV-SGLPSEGASEGNQYTPDAQRFNCQKPD 296
+LKIT D +VL +QSK+QAEQWL+VI+E SG SE P K +
Sbjct: 216 ELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDSE----CPPPPSSPVHKAE 271
Query: 297 IAEKYLSASEYGSSVDGHPEVPET-----KDVKKKCSA------------GLKLSNLMNL 339
+ EK LS+ S +G E T + VK+K S+ G K++ +++L
Sbjct: 272 L-EKKLSSERPSSDGEGVVENGITTCNGKEQVKRKKSSKSEAKGTVSKVTGKKITKIISL 330
Query: 340 GRKKSTSLE---PVERSLETSSYLNVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPL 396
G+KK ++ E E + T YLNVL NS+W+ RWC V+DN L F++DR K +
Sbjct: 331 GKKKPSTDEQTSSAEEDVPTCGYLNVLSNSRWRERWCRVKDNKLIFHKDRTDLKTHIVSI 390
Query: 397 SLVGCEVVPDPSPDHLYSFRILHKGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFT 456
L GCEV+P H +FR+L G+E+A LEA SSE+MG W+G+LL+E+GS TDPE
Sbjct: 391 PLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALH 450
Query: 457 YDYVDADRVSCIVSAAKNSLLLMQRKFSEPNTYIDG 492
YDY+D + + ++ AK + M R+ N Y+ G
Sbjct: 451 YDYIDVEMSASVIQTAKQTFCFMNRRVISANPYLGG 486
Score = 122 bits (306), Expect = 1e-27
Identities = 80/200 (40%), Positives = 114/200 (57%), Gaps = 20/200 (10%)
Query: 636 PPGASPP-VKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKR 694
P A P V R +A+ K GKNR EA+ KR ++E L K+KE +R LAQLRKE++
Sbjct: 534 PKKADPAAVVKRTGSNAAQYKYGKNRVEADAKRLQTKEEELLKRKEALRNRLAQLRKERK 593
Query: 695 ELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEAGPVTL 754
+L+ + ++ A LE+KLK+++EECR +E+ RV LEL + EVK++LKKA AG VTL
Sbjct: 594 DLRAAIEVNAGRKPQAILEEKLKQLEEECRQKEAERVSLELELTEVKESLKKALAGGVTL 653
Query: 755 GTTVD----TTHLENVSPRPKAVTPASAPDC--------TPVNSATTLKNRPLSVVVTG- 801
G ++ T+ ++ R + + + C PVNSA LK S G
Sbjct: 654 GLAIEPKSGTSSPQSPVFRHRTLENSPISSCDTSDTEGPVPVNSAAVLKK---SQAAPGS 710
Query: 802 ---KGTVLQKAKEWEKKGAS 818
+G VL+KAKEWE K +
Sbjct: 711 SPCRGHVLRKAKEWELKNGT 730
>gi|226437595 actin filament associated protein 1-like 1 isoform 2
[Homo sapiens]
Length = 725
Score = 312 bits (800), Expect = 7e-85
Identities = 214/575 (37%), Positives = 303/575 (52%), Gaps = 81/575 (14%)
Query: 1 MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKV 60
M+R + LEQLL EL L +LD E LS T L KK +A +L+ + + Y+Y+N
Sbjct: 1 MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA 60
Query: 61 TINKQQN------------AESQGKAPEEQGLLPNGEPSQHSSAPQ-KSLPDLPPP---K 104
++ + PE+ G G + + +P+ ++ DLPPP K
Sbjct: 61 DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK 120
Query: 105 MIPE---RKQLAIPKTESPE----------------GYYEEAEPYDTSLNEDGE------ 139
PE + L + +SPE GYYE+A+ + +GE
Sbjct: 121 PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN 180
Query: 140 ---AVSSSYESYDEEDGSKGKSAP--YQWPSPEAGIELMRDARICAFLWRKKWLGQWAKQ 194
A+SSSYESYDEE+ +GKS +QWPS EA + L+R+ RICAFL RKK GQWAKQ
Sbjct: 181 DSDAMSSSYESYDEEE-EEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQ 239
Query: 195 LCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLKITPMNADVIVLGLQ 254
L VI++++LLCYKSSKD P L + L S+I+ K R K H+L+ T +V+VL LQ
Sbjct: 240 LTVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQ 299
Query: 255 SKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEKYLSASEYGSSVD-- 312
S++QAE+WL+VI+EVS G +EG + P + C K D+ +K LS + S D
Sbjct: 300 SREQAEEWLKVIREVS--KPVGGAEGVE-VPRSPVLLC-KLDL-DKRLSQEKQTSDSDSV 354
Query: 313 ---------GHPEVPETKDVKKKC----------SAGLKLSNLMNLGRKKSTS----LEP 349
G E + KK +AG K++ ++ +KK+ +
Sbjct: 355 GVGDNCSTLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSS 414
Query: 350 VERSLETSSYLNVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSP 409
E + YLNVLVN WK RWC ++ N L+F++D + ++L GCEV P P
Sbjct: 415 TEEEVPCCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGP 474
Query: 410 DHLYSFRILHKGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIV 469
H ++FRIL +E+A LEA SE+MG WLGLLL E GS+ PE YDYVD + ++ IV
Sbjct: 475 RHPFAFRILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIV 534
Query: 470 SAAKNSLLL---MQRKFSEPNTYIDGLPSQDRQEE 501
SA +NS L Q ++ EP Y D +P + Q+E
Sbjct: 535 SAGRNSFLYARSCQNQWPEPRVY-DDVPYEKMQDE 568
Score = 97.4 bits (241), Expect = 5e-20
Identities = 53/121 (43%), Positives = 80/121 (66%), Gaps = 2/121 (1%)
Query: 641 PPVKDRLRVTSA-EIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKET 699
P VK + +SA + K GKNR E + +RY EKE+LEK+KE IR L LR+EKRELKE
Sbjct: 594 PQVKVKRHASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEA 653
Query: 700 LLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVD 759
++ + L +LE+ + ++ +CR +E RR+DLEL ++ VK+ L+++ AG LG +V
Sbjct: 654 -IRSSPGAKLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVS 712
Query: 760 T 760
+
Sbjct: 713 S 713
>gi|55742689 actin filament associated protein 1-like 1 isoform 1
[Homo sapiens]
Length = 768
Score = 312 bits (800), Expect = 7e-85
Identities = 214/575 (37%), Positives = 303/575 (52%), Gaps = 81/575 (14%)
Query: 1 MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKV 60
M+R + LEQLL EL L +LD E LS T L KK +A +L+ + + Y+Y+N
Sbjct: 1 MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA 60
Query: 61 TINKQQN------------AESQGKAPEEQGLLPNGEPSQHSSAPQ-KSLPDLPPP---K 104
++ + PE+ G G + + +P+ ++ DLPPP K
Sbjct: 61 DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK 120
Query: 105 MIPE---RKQLAIPKTESPE----------------GYYEEAEPYDTSLNEDGE------ 139
PE + L + +SPE GYYE+A+ + +GE
Sbjct: 121 PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN 180
Query: 140 ---AVSSSYESYDEEDGSKGKSAP--YQWPSPEAGIELMRDARICAFLWRKKWLGQWAKQ 194
A+SSSYESYDEE+ +GKS +QWPS EA + L+R+ RICAFL RKK GQWAKQ
Sbjct: 181 DSDAMSSSYESYDEEE-EEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQ 239
Query: 195 LCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLKITPMNADVIVLGLQ 254
L VI++++LLCYKSSKD P L + L S+I+ K R K H+L+ T +V+VL LQ
Sbjct: 240 LTVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQ 299
Query: 255 SKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEKYLSASEYGSSVD-- 312
S++QAE+WL+VI+EVS G +EG + P + C K D+ +K LS + S D
Sbjct: 300 SREQAEEWLKVIREVS--KPVGGAEGVE-VPRSPVLLC-KLDL-DKRLSQEKQTSDSDSV 354
Query: 313 ---------GHPEVPETKDVKKKC----------SAGLKLSNLMNLGRKKSTS----LEP 349
G E + KK +AG K++ ++ +KK+ +
Sbjct: 355 GVGDNCSTLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSS 414
Query: 350 VERSLETSSYLNVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSP 409
E + YLNVLVN WK RWC ++ N L+F++D + ++L GCEV P P
Sbjct: 415 TEEEVPCCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGP 474
Query: 410 DHLYSFRILHKGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIV 469
H ++FRIL +E+A LEA SE+MG WLGLLL E GS+ PE YDYVD + ++ IV
Sbjct: 475 RHPFAFRILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIV 534
Query: 470 SAAKNSLLL---MQRKFSEPNTYIDGLPSQDRQEE 501
SA +NS L Q ++ EP Y D +P + Q+E
Sbjct: 535 SAGRNSFLYARSCQNQWPEPRVY-DDVPYEKMQDE 568
Score = 127 bits (319), Expect = 4e-29
Identities = 76/182 (41%), Positives = 111/182 (60%), Gaps = 16/182 (8%)
Query: 641 PPVKDRLRVTSA-EIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKET 699
P VK + +SA + K GKNR E + +RY EKE+LEK+KE IR L LR+EKRELKE
Sbjct: 594 PQVKVKRHASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEA 653
Query: 700 LLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVD 759
++ + L +LE+ + ++ +CR +E RR+DLEL ++ VK+ L+++ AG LG
Sbjct: 654 -IRSSPGAKLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGL--- 709
Query: 760 TTHLENVSPRPKAVTPASAPDCT------PVNSATTLKNRPLSVVVTGKGTVLQKAKEWE 813
+VS +PK+ A+ P + PVN + L+ R S+V + +G VLQKAKEWE
Sbjct: 710 -----SVSSKPKSGETANKPQNSVPEQPLPVNCVSELRKRSPSIVASNQGRVLQKAKEWE 764
Query: 814 KK 815
K
Sbjct: 765 MK 766
>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sapiens]
Length = 2365
Score = 54.3 bits (129), Expect = 4e-07
Identities = 92/427 (21%), Positives = 156/427 (36%), Gaps = 46/427 (10%)
Query: 348 EPVERSLETSSYLNVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQ--QPLSLVGCEVVP 405
EP SL T+S SQWK W + D+ L +Y+D + + + L C V
Sbjct: 1793 EPPSPSLTTTS------TSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVT 1846
Query: 406 DPSPDHLYSFRILHKGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRV 465
+ + Y F+I H + + L A +S +W+ L + P+ + +
Sbjct: 1847 EYAVQRNYGFQI-HTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKENA 1905
Query: 466 SCIVSAAKNSLLLMQRKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVA 525
S K L +++ G D Q + D V+LS LT A P TP
Sbjct: 1906 LHSYSTQKGPLKAGEQRAGSEVISRGGPRKADGQRQALDYVELSPLTQA-SPQRARTPAR 1964
Query: 526 DDPNERESDRVYLDLTPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEP 585
+ + + DL + +++ D+ T +PA GP P
Sbjct: 1965 TPDRLAKQEELERDL-----------AQRSEERRKWFEATDSRTPEVPAGEGPRRGLGAP 2013
Query: 586 CIKCPEN-LGE------QQLESLE-PEDPSLRITTVKIQTEQQRISFPPSCPDAVVATP- 636
+ +N L E Q+LE L E+ + +T + Q+ +R P +A+
Sbjct: 2014 LTEDQQNRLSEEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHEALEKEVQ 2073
Query: 637 -----------PGASPPVKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGH 685
G +P R + I G EA + E + ++ EE++ H
Sbjct: 2074 ALRAQLEAWRLQGEAPQSALRSQ-EDGHIPPGYISQEACERSLAEMESSHQQVMEELQRH 2132
Query: 686 LAQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLK 745
+ + ++ KE LL +++E K EE SR + S+ + D L+
Sbjct: 2133 HERELQRLQQEKEWLLAEETAATASAIEAMKKAYQEEL----SRELSKTRSLQQGPDGLR 2188
Query: 746 KAEAGPV 752
K V
Sbjct: 2189 KQHQSDV 2195
>gi|88501740 TRIO and F-actin binding protein isoform 1 [Homo
sapiens]
Length = 652
Score = 54.3 bits (129), Expect = 4e-07
Identities = 92/427 (21%), Positives = 156/427 (36%), Gaps = 46/427 (10%)
Query: 348 EPVERSLETSSYLNVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQ--QPLSLVGCEVVP 405
EP SL T+S SQWK W + D+ L +Y+D + + + L C V
Sbjct: 80 EPPSPSLTTTS------TSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVT 133
Query: 406 DPSPDHLYSFRILHKGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRV 465
+ + Y F+I H + + L A +S +W+ L + P+ + +
Sbjct: 134 EYAVQRNYGFQI-HTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKENA 192
Query: 466 SCIVSAAKNSLLLMQRKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVA 525
S K L +++ G D Q + D V+LS LT A P TP
Sbjct: 193 LHSYSTQKGPLKAGEQRAGSEVISRGGPRKADGQRQALDYVELSPLTQA-SPQRARTPAR 251
Query: 526 DDPNERESDRVYLDLTPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEP 585
+ + + DL + +++ D+ T +PA GP P
Sbjct: 252 TPDRLAKQEELERDL-----------AQRSEERRKWFEATDSRTPEVPAGEGPRRGLGAP 300
Query: 586 CIKCPEN-LGE------QQLESLE-PEDPSLRITTVKIQTEQQRISFPPSCPDAVVATP- 636
+ +N L E Q+LE L E+ + +T + Q+ +R P +A+
Sbjct: 301 LTEDQQNRLSEEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHEALEKEVQ 360
Query: 637 -----------PGASPPVKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGH 685
G +P R + I G EA + E + ++ EE++ H
Sbjct: 361 ALRAQLEAWRLQGEAPQSALRSQ-EDGHIPPGYISQEACERSLAEMESSHQQVMEELQRH 419
Query: 686 LAQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLK 745
+ + ++ KE LL +++E K EE SR + S+ + D L+
Sbjct: 420 HERELQRLQQEKEWLLAEETAATASAIEAMKKAYQEEL----SRELSKTRSLQQGPDGLR 475
Query: 746 KAEAGPV 752
K V
Sbjct: 476 KQHQSDV 482
>gi|88501741 TRIO and F-actin binding protein isoform 2 [Homo
sapiens]
Length = 431
Score = 50.1 bits (118), Expect = 8e-06
Identities = 55/254 (21%), Positives = 94/254 (37%), Gaps = 21/254 (8%)
Query: 348 EPVERSLETSSYLNVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQ--QPLSLVGCEVVP 405
EP SL T+S SQWK W + D+ L +Y+D + + + L C V
Sbjct: 80 EPPSPSLTTTS------TSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVT 133
Query: 406 DPSPDHLYSFRILHKGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRV 465
+ + Y F+I H + + L A +S +W+ L + P+ + +
Sbjct: 134 EYAVQRNYGFQI-HTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKENA 192
Query: 466 SCIVSAAKNSLLLMQRKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVA 525
S K L +++ G D Q + D V+LS LT A P TP
Sbjct: 193 LHSYSTQKGPLKAGEQRAGSEVISRGGPRKADGQRQALDYVELSPLTQA-SPQRARTPAR 251
Query: 526 DDPNERESDRVYLDLTPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEP 585
+ + + DL + +++ D+ T +PA GP P
Sbjct: 252 TPDRLAKQEELERDL-----------AQRSEERRKWFEATDSRTPEVPAGEGPRRGLGAP 300
Query: 586 CIKCPENLGEQQLE 599
+ +N +++E
Sbjct: 301 LTEDQQNRLSEEIE 314
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 46.2 bits (108), Expect = 1e-04
Identities = 32/116 (27%), Positives = 61/116 (52%), Gaps = 19/116 (16%)
Query: 645 DRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCT 704
D L +T A+++ K+ TE +VK TEE L++ +A+L +EK+ L+E +
Sbjct: 956 DDLELTLAKVEKEKHATENKVKNLTEELSGLDET-------IAKLTREKKALQEAHQQAL 1008
Query: 705 D------------KEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAE 748
D + + LEQ++++++ E+ RVDLE + +++ +LK A+
Sbjct: 1009 DDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQ 1064
Score = 33.5 bits (75), Expect = 0.82
Identities = 23/101 (22%), Positives = 50/101 (49%), Gaps = 6/101 (5%)
Query: 651 SAEIKLGKNRTEA-----EVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTD 705
+AE K K T+A E+K+ + LE+ K+ + + L+ E ++ LK
Sbjct: 1751 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1810
Query: 706 KEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
K++ LE +++E++ E GE+ + + + + + +K+
Sbjct: 1811 KQI-QKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKE 1850
Score = 32.7 bits (73), Expect = 1.4
Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 687 AQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
A+ KE +KE K D+ LA E K KE++E+ + DL+L + +NL
Sbjct: 844 AETEKEMATMKEEFQKTKDE--LAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLD 901
Query: 747 AE 748
AE
Sbjct: 902 AE 903
Score = 32.0 bits (71), Expect = 2.4
Identities = 34/155 (21%), Positives = 63/155 (40%), Gaps = 6/155 (3%)
Query: 595 EQQLESLEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEI 654
E+Q+E++ + SL T ++Q E + + +++ A L +
Sbjct: 1402 EEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKC 1461
Query: 655 KLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQ 714
+ + EA +K L K K L QL KRE K ++ +A L +
Sbjct: 1462 EESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNL------EQEIADLTE 1515
Query: 715 KLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEA 749
++ E + E R +EL +++ L++AEA
Sbjct: 1516 QIAENGKTIHELEKSRKQIELEKADIQLALEEAEA 1550
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 46.2 bits (108), Expect = 1e-04
Identities = 73/342 (21%), Positives = 141/342 (41%), Gaps = 65/342 (19%)
Query: 422 EELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSLLLMQR 481
EELA+ EA+ E + LL ++ + + T + +DA+ C S +L++
Sbjct: 865 EELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEE-RC--EGLIKSKILLEA 921
Query: 482 KFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVADDPNERESDRVYLDLT 541
K E + + +EE+ SEL A E+ +R+ D + L LT
Sbjct: 922 KVKELTERL------EEEEEMN-----SELVAKKRNLEDKC----SSLKRDIDDLELTLT 966
Query: 542 PVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLESL 601
V+ H + + + S ++ L+ L + K + +Q L+ L
Sbjct: 967 KVEKEKHATEN-KVKNLSEEMTALEENISKLTKEK-----------KSLQEAHQQTLDDL 1014
Query: 602 EPEDPSLR-ITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNR 660
+ E+ + + + + EQQ S + +LR A+++ K +
Sbjct: 1015 QVEEDKVNGLIKINAKLEQQTDDLEGSLEQ-------------EKKLR---ADLERAKRK 1058
Query: 661 TEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEV--------LASL 712
E ++K E LE K++I +L+K++ EL + K D++V + L
Sbjct: 1059 LEGDLKMSQESIMDLENDKQQIE---EKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKEL 1115
Query: 713 EQKLKEIDEECRGE-------ESRRVDLELSIMEVKDNLKKA 747
+ +++E++EE E E +R DL + E+ + L++A
Sbjct: 1116 QARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEA 1157
Score = 37.4 bits (85), Expect = 0.057
Identities = 38/160 (23%), Positives = 69/160 (43%), Gaps = 40/160 (25%)
Query: 645 DRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCT 704
D L +T +++ K+ TE +VK +EE LE+ ++++L KEK+ L+E +
Sbjct: 959 DDLELTLTKVEKEKHATENKVKNLSEEMTALEE-------NISKLTKEKKSLQEAHQQTL 1011
Query: 705 DK------------EVLASLEQKLKEIDEECRGEESRRVDLEL--------------SIM 738
D ++ A LEQ+ +++ E+ R DLE SIM
Sbjct: 1012 DDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIM 1071
Query: 739 E-------VKDNLKKAEAGPVTLGTTVDTTHLENVSPRPK 771
+ +++ LKK E L +D + ++ + K
Sbjct: 1072 DLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKK 1111
Score = 32.0 bits (71), Expect = 2.4
Identities = 25/122 (20%), Positives = 54/122 (44%), Gaps = 23/122 (18%)
Query: 644 KDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKC 703
K +L + AE++ + E + + E ++ EE+ L LR+E + L+E +
Sbjct: 1461 KQKLDESQAELEAAQK----ESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDL 1516
Query: 704 TDK-------------------EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNL 744
T++ + + L+ L+E++ EES+ + ++L + +VK L
Sbjct: 1517 TEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSEL 1576
Query: 745 KK 746
+
Sbjct: 1577 DR 1578
Score = 31.2 bits (69), Expect = 4.1
Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 687 AQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
A+ KE +KE + KE LA E + KE++E+ + DL+L + +NL
Sbjct: 847 AEAEKEMATMKEDFERT--KEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMD 904
Query: 747 AE 748
AE
Sbjct: 905 AE 906
Score = 30.4 bits (67), Expect = 6.9
Identities = 22/84 (26%), Positives = 42/84 (50%), Gaps = 6/84 (7%)
Query: 651 SAEIKLGKNRTEA-----EVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTD 705
+AE K K T+A E+K+ + LE+ K+ + + L+ E ++ LK
Sbjct: 1754 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1813
Query: 706 KEVLASLEQKLKEIDEECRGEESR 729
K++ LE +++E++ E E+ R
Sbjct: 1814 KQI-QKLENRVRELENELDVEQKR 1836
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 45.8 bits (107), Expect = 2e-04
Identities = 27/106 (25%), Positives = 57/106 (53%), Gaps = 1/106 (0%)
Query: 644 KDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLK- 702
++RLR ++ + R + +R E++ERL +++E +R +L +++ L+E +
Sbjct: 198 EERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERL 257
Query: 703 CTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAE 748
C +E L E++L+E +E +E R + E + E ++ L + E
Sbjct: 258 CEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQE 303
Score = 42.7 bits (99), Expect = 0.001
Identities = 37/160 (23%), Positives = 74/160 (46%), Gaps = 19/160 (11%)
Query: 593 LGEQQLESLEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSA 652
L +Q E L ++ LR +++ +++R+ C ++RLR
Sbjct: 193 LNRRQEERLREQEERLREQEERLREQEERL-----CEQ-------------EERLREQEE 234
Query: 653 EIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLK-CTDKEVLAS 711
++ + R + +R E +ERL +++E + +LR+++ L E + C +E L
Sbjct: 235 RLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLRE 294
Query: 712 LEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEAGP 751
E++L E +E R +E R + E + E ++ L + E P
Sbjct: 295 QEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLP 334
Score = 38.5 bits (88), Expect = 0.025
Identities = 26/108 (24%), Positives = 59/108 (54%), Gaps = 5/108 (4%)
Query: 644 KDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKC 703
++RLR + + R + +R E++ERL +++E +R +L +++ L+E +
Sbjct: 268 EERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERL 327
Query: 704 TDKEVLASLEQKLKEID-----EECRGEESRRVDLELSIMEVKDNLKK 746
++E L E+ L+E++ E + E+ R ++ E + EV++ L++
Sbjct: 328 CEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQ 375
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 45.4 bits (106), Expect = 2e-04
Identities = 33/116 (28%), Positives = 60/116 (51%), Gaps = 19/116 (16%)
Query: 645 DRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCT 704
D L +T A+++ K+ TE +VK TEE L++ +A+L KEK+ L+ET +
Sbjct: 958 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDET-------IAKLSKEKKALQETHQQTL 1010
Query: 705 DK------------EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAE 748
D + LEQ++ +++ E+ R+DLE + +++ +LK A+
Sbjct: 1011 DDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1066
Score = 38.1 bits (87), Expect = 0.033
Identities = 74/330 (22%), Positives = 133/330 (40%), Gaps = 41/330 (12%)
Query: 422 EELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSLLLMQR 481
+ELAK EAK E + LL ++ + + DA+ C KN + L +
Sbjct: 864 DELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEE-RC-EQLIKNKIQL-EA 920
Query: 482 KFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVADDPNERESDRVYLDLT 541
K E +R EE ++ +ELTA E+ +++ D + L L
Sbjct: 921 KIKEVT---------ERAEE--EEEINAELTAKKRKLEDECSEL----KKDIDDLELTLA 965
Query: 542 PVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLESL 601
V+ H + + + + ++ LD L + K + +Q L+ L
Sbjct: 966 KVEKEKHATEN-KVKNLTEEMAGLDETIAKLSKEK-----------KALQETHQQTLDDL 1013
Query: 602 EPEDPSLRITT-VKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNR 660
+ E+ + I T K + EQQ S + ++ R ++KL +
Sbjct: 1014 QAEEDKVNILTKAKTKLEQQVDDLEGS-----LEQEKKLRMDLERAKRKLEGDLKLAQES 1068
Query: 661 TEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEID 720
T + E+LEKK+ EI ++++ E + E L+ KE+ A +E+ +EI+
Sbjct: 1069 TMDMENDKQQLDEKLEKKEFEISNLISKI--EDEQAVEIQLQKKIKELQARIEELGEEIE 1126
Query: 721 EECRGE---ESRRVDLELSIMEVKDNLKKA 747
E E +R DL + E+ + L++A
Sbjct: 1127 AERASRAKAEKQRSDLSRELEEISERLEEA 1156
Score = 32.3 bits (72), Expect = 1.8
Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 687 AQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
A+ KE +KE K D+ LA E K KE++E+ + DL+L + D+L
Sbjct: 846 AETEKEMATMKEEFQKTKDE--LAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903
Query: 747 AE 748
AE
Sbjct: 904 AE 905
Score = 32.0 bits (71), Expect = 2.4
Identities = 22/87 (25%), Positives = 43/87 (49%), Gaps = 6/87 (6%)
Query: 651 SAEIKLGKNRTEA-----EVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTD 705
+AE K K T+A E+K+ + LE+ K+ + + L+ E ++ LK
Sbjct: 1753 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1812
Query: 706 KEVLASLEQKLKEIDEECRGEESRRVD 732
K++ LE +++E++ E E+ R +
Sbjct: 1813 KQI-QKLEARVRELEGEVENEQKRNAE 1838
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 45.1 bits (105), Expect = 3e-04
Identities = 51/190 (26%), Positives = 79/190 (41%), Gaps = 33/190 (17%)
Query: 598 LESLEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPP-GASPPV------------- 643
LES ED L +++ + PP+ P +T P S P+
Sbjct: 272 LESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGSTE 331
Query: 644 KDRLRVTSAEIKLGKN---RTEAEVK----------------RYTEEKERLEKKKEEIRG 684
K++LR+ + +LGK R E E K + EEKE EK++ E R
Sbjct: 332 KNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKRE 391
Query: 685 HLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNL 744
+ + EK+ LKE K + + A LE+K K+ +E+ EE +R+ E + +
Sbjct: 392 KDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQK 451
Query: 745 KKAEAGPVTL 754
K P TL
Sbjct: 452 PKTPQAPKTL 461
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 43.1 bits (100), Expect = 0.001
Identities = 32/116 (27%), Positives = 59/116 (50%), Gaps = 19/116 (16%)
Query: 645 DRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCT 704
D L +T A+++ K+ TE +VK TEE L++ +A+L KEK+ L+E +
Sbjct: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDET-------IAKLTKEKKALQEAHQQTL 1013
Query: 705 DK------------EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAE 748
D + LEQ++ +++ E+ R+DLE + +++ +LK A+
Sbjct: 1014 DDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1069
Score = 32.3 bits (72), Expect = 1.8
Identities = 57/258 (22%), Positives = 99/258 (38%), Gaps = 50/258 (19%)
Query: 507 DLSELTAAVEPTEEATPVADDPNERESDRVYLDLTPVKSFLHGPSSAQAQASSPTLSCLD 566
++ EL A +E TE + +A+ S+RV L T S ++ + S D
Sbjct: 1690 EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMED 1749
Query: 567 NATEALPADSGPGPTPDEPCIKCPENLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPP 626
EA A+ E K + E + +D S + +K EQ
Sbjct: 1750 ILQEARNAE--------EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT------ 1795
Query: 627 SCPDAVVATPPGASPPVKD-RLRVTSAE---IKLGKN---RTEAEVKRYTEEKERLEKKK 679
VKD +LR+ AE +K GK + EA V+ E E +K+
Sbjct: 1796 ----------------VKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRN 1839
Query: 680 EE-IRGHLAQLRKEKRELKETLLKCTD--------KEVLASLEQKLKEIDEECRGEESRR 730
E ++G LRK +R +KE + + ++++ L+ K+K + E +
Sbjct: 1840 AEAVKG----LRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQS 1895
Query: 731 VDLELSIMEVKDNLKKAE 748
+++ L++AE
Sbjct: 1896 NTNLAKFRKLQHELEEAE 1913
Score = 30.4 bits (67), Expect = 6.9
Identities = 22/116 (18%), Positives = 53/116 (45%), Gaps = 9/116 (7%)
Query: 643 VKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETL-- 700
VK +L +E+K+ + + V+ ++ K LEK + L++L+ ++ E + +
Sbjct: 1219 VKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIND 1278
Query: 701 -------LKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEA 749
L+ E L++K + + RG+++ +E ++++ +K A
Sbjct: 1279 LTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNA 1334
Score = 30.0 bits (66), Expect = 9.0
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
Query: 687 AQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
A+ KE +KE K D+ LA E K KE++E+ + DL+L + + L
Sbjct: 849 AETEKEMATMKEEFQKIKDE--LAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906
Query: 747 AE 748
AE
Sbjct: 907 AE 908
Score = 30.0 bits (66), Expect = 9.0
Identities = 31/113 (27%), Positives = 55/113 (48%), Gaps = 20/113 (17%)
Query: 643 VKDRLRVTSAEIKLGKNRTEAEVKRYT--EEKERLEKKKEEIRGHLA-------QLRKEK 693
+KD L + A+ R E E K T +EK L+ + + LA QL K K
Sbjct: 865 IKDELAKSEAK------RKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTK 918
Query: 694 RELKETLLKCTDK-----EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVK 741
+L+ + + T++ E+ A L K +++++EC + DLEL++ +V+
Sbjct: 919 IQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 43.1 bits (100), Expect = 0.001
Identities = 32/116 (27%), Positives = 59/116 (50%), Gaps = 19/116 (16%)
Query: 645 DRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCT 704
D L +T A+++ K+ TE +VK TEE L++ +A+L KEK+ L+E +
Sbjct: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDET-------IAKLTKEKKALQEAHQQTL 1013
Query: 705 DK------------EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAE 748
D + LEQ++ +++ E+ R+DLE + +++ +LK A+
Sbjct: 1014 DDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1069
Score = 32.3 bits (72), Expect = 1.8
Identities = 57/258 (22%), Positives = 99/258 (38%), Gaps = 50/258 (19%)
Query: 507 DLSELTAAVEPTEEATPVADDPNERESDRVYLDLTPVKSFLHGPSSAQAQASSPTLSCLD 566
++ EL A +E TE + +A+ S+RV L T S ++ + S D
Sbjct: 1690 EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMED 1749
Query: 567 NATEALPADSGPGPTPDEPCIKCPENLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPP 626
EA A+ E K + E + +D S + +K EQ
Sbjct: 1750 ILQEARNAE--------EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT------ 1795
Query: 627 SCPDAVVATPPGASPPVKD-RLRVTSAE---IKLGKN---RTEAEVKRYTEEKERLEKKK 679
VKD +LR+ AE +K GK + EA V+ E E +K+
Sbjct: 1796 ----------------VKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRN 1839
Query: 680 EE-IRGHLAQLRKEKRELKETLLKCTD--------KEVLASLEQKLKEIDEECRGEESRR 730
E ++G LRK +R +KE + + ++++ L+ K+K + E +
Sbjct: 1840 AEAVKG----LRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQS 1895
Query: 731 VDLELSIMEVKDNLKKAE 748
+++ L++AE
Sbjct: 1896 NTNLAKFRKLQHELEEAE 1913
Score = 30.4 bits (67), Expect = 6.9
Identities = 22/116 (18%), Positives = 53/116 (45%), Gaps = 9/116 (7%)
Query: 643 VKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETL-- 700
VK +L +E+K+ + + V+ ++ K LEK + L++L+ ++ E + +
Sbjct: 1219 VKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIND 1278
Query: 701 -------LKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEA 749
L+ E L++K + + RG+++ +E ++++ +K A
Sbjct: 1279 LTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNA 1334
Score = 30.0 bits (66), Expect = 9.0
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
Query: 687 AQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
A+ KE +KE K D+ LA E K KE++E+ + DL+L + + L
Sbjct: 849 AETEKEMATMKEEFQKIKDE--LAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906
Query: 747 AE 748
AE
Sbjct: 907 AE 908
Score = 30.0 bits (66), Expect = 9.0
Identities = 31/113 (27%), Positives = 55/113 (48%), Gaps = 20/113 (17%)
Query: 643 VKDRLRVTSAEIKLGKNRTEAEVKRYT--EEKERLEKKKEEIRGHLA-------QLRKEK 693
+KD L + A+ R E E K T +EK L+ + + LA QL K K
Sbjct: 865 IKDELAKSEAK------RKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTK 918
Query: 694 RELKETLLKCTDK-----EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVK 741
+L+ + + T++ E+ A L K +++++EC + DLEL++ +V+
Sbjct: 919 IQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971
>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
sapiens]
Length = 638
Score = 42.7 bits (99), Expect = 0.001
Identities = 41/189 (21%), Positives = 82/189 (43%), Gaps = 17/189 (8%)
Query: 592 NLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTS 651
N + E+L E +L+ + Q E++++ D+++ S + +L
Sbjct: 219 NRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQ 278
Query: 652 AEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLAS 711
E+ KN E E+K+ +E ++L++K+E+ + QL +E + + E L
Sbjct: 279 EEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAK---------SRAEELKL 329
Query: 712 LEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKA--------EAGPVTLGTTVDTTHL 763
LE+KLK + E + L + E D++ ++ E+ + ++ L
Sbjct: 330 LEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKL 389
Query: 764 ENVSPRPKA 772
EN S + KA
Sbjct: 390 ENSSLQEKA 398
>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
sapiens]
Length = 725
Score = 42.7 bits (99), Expect = 0.001
Identities = 41/189 (21%), Positives = 82/189 (43%), Gaps = 17/189 (8%)
Query: 592 NLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTS 651
N + E+L E +L+ + Q E++++ D+++ S + +L
Sbjct: 306 NRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQ 365
Query: 652 AEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLAS 711
E+ KN E E+K+ +E ++L++K+E+ + QL +E + + E L
Sbjct: 366 EEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAK---------SRAEELKL 416
Query: 712 LEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKA--------EAGPVTLGTTVDTTHL 763
LE+KLK + E + L + E D++ ++ E+ + ++ L
Sbjct: 417 LEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKL 476
Query: 764 ENVSPRPKA 772
EN S + KA
Sbjct: 477 ENSSLQEKA 485
>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
sapiens]
Length = 709
Score = 42.7 bits (99), Expect = 0.001
Identities = 41/189 (21%), Positives = 82/189 (43%), Gaps = 17/189 (8%)
Query: 592 NLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTS 651
N + E+L E +L+ + Q E++++ D+++ S + +L
Sbjct: 290 NRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQ 349
Query: 652 AEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLAS 711
E+ KN E E+K+ +E ++L++K+E+ + QL +E + + E L
Sbjct: 350 EEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAK---------SRAEELKL 400
Query: 712 LEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKA--------EAGPVTLGTTVDTTHL 763
LE+KLK + E + L + E D++ ++ E+ + ++ L
Sbjct: 401 LEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKL 460
Query: 764 ENVSPRPKA 772
EN S + KA
Sbjct: 461 ENSSLQEKA 469
>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
sapiens]
Length = 724
Score = 42.7 bits (99), Expect = 0.001
Identities = 41/189 (21%), Positives = 82/189 (43%), Gaps = 17/189 (8%)
Query: 592 NLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTS 651
N + E+L E +L+ + Q E++++ D+++ S + +L
Sbjct: 305 NRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQ 364
Query: 652 AEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLAS 711
E+ KN E E+K+ +E ++L++K+E+ + QL +E + + E L
Sbjct: 365 EEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAK---------SRAEELKL 415
Query: 712 LEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKA--------EAGPVTLGTTVDTTHL 763
LE+KLK + E + L + E D++ ++ E+ + ++ L
Sbjct: 416 LEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKL 475
Query: 764 ENVSPRPKA 772
EN S + KA
Sbjct: 476 ENSSLQEKA 484
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 42.7 bits (99), Expect = 0.001
Identities = 32/116 (27%), Positives = 59/116 (50%), Gaps = 19/116 (16%)
Query: 645 DRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCT 704
D L +T A+++ K+ TE +VK TEE L++ +A+L KEK+ L+E +
Sbjct: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDET-------IAKLTKEKKALQEAHQQTL 1011
Query: 705 DK------------EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAE 748
D + LEQ++ +++ E+ R+DLE + +++ +LK A+
Sbjct: 1012 DDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQ 1067
Score = 33.5 bits (75), Expect = 0.82
Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 687 AQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
A+ KE +KE K KE LA E K KE++E+ + DL+L + D+L
Sbjct: 847 AETEKEMANMKEEFEKT--KEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLAD 904
Query: 747 AE 748
AE
Sbjct: 905 AE 906
Score = 33.5 bits (75), Expect = 0.82
Identities = 23/87 (26%), Positives = 44/87 (50%), Gaps = 6/87 (6%)
Query: 651 SAEIKLGKNRTEA-----EVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTD 705
+AE K K T+A E+K+ + LE+ K+ + + L+ E ++ LK
Sbjct: 1754 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1813
Query: 706 KEVLASLEQKLKEIDEECRGEESRRVD 732
K++ LE +++E++ E E+ R V+
Sbjct: 1814 KQI-QKLEARVRELEGEVESEQKRNVE 1839
Score = 32.0 bits (71), Expect = 2.4
Identities = 31/114 (27%), Positives = 55/114 (48%), Gaps = 15/114 (13%)
Query: 643 VKDRLRVTSAEI-KLGKNRTEAEVKRYT--EEKERLEKKKEEIRGHLA-------QLRKE 692
+K+ T E+ K R E E K T +EK L+ + + LA QL K
Sbjct: 856 MKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKT 915
Query: 693 KRELKETLLKCTDK-----EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVK 741
K +L+ + + T++ E+ A L K +++++EC + DLEL++ +V+
Sbjct: 916 KIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 969
Score = 31.2 bits (69), Expect = 4.1
Identities = 59/259 (22%), Positives = 101/259 (38%), Gaps = 52/259 (20%)
Query: 507 DLSELTAAVEPTEEATPVADDPNERESDRVYLDLTPVKSFLHGPSSAQAQASSPTLSCLD 566
++ EL A +E TE + +A+ S+RV L T S ++ + S D
Sbjct: 1688 EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMED 1747
Query: 567 NATEALPADSGPGPTPDEPCIKCPENLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPP 626
EA A+ E K + E + +D S + +K EQ
Sbjct: 1748 IIQEARNAE--------EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT------ 1793
Query: 627 SCPDAVVATPPGASPPVKD-RLRVTSAE---IKLGKN---RTEAEVKRYTEEKERLEKKK 679
VKD + R+ AE +K GK + EA V+ E E +K+
Sbjct: 1794 ----------------VKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRN 1837
Query: 680 -EEIRGHLAQLRKEKRELKETLLKCTD--------KEVLASLEQKLKEIDEEC-RGEESR 729
E ++G LRK +R++KE + + ++++ L+ K+K + EE
Sbjct: 1838 VEAVKG----LRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQS 1893
Query: 730 RVDLELSIMEVKDNLKKAE 748
V+L ++ L++AE
Sbjct: 1894 NVNLS-KFRRIQHELEEAE 1911
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 42.4 bits (98), Expect = 0.002
Identities = 35/108 (32%), Positives = 56/108 (51%), Gaps = 6/108 (5%)
Query: 643 VKDRLRVTSAEIKLGKNRTEAEVKRYTEEKER---LEKKKEEIRGHLAQLRKEKRELKET 699
++ RL+ E + R E +KR E+ER L K +E+ QLR+E++E +E
Sbjct: 598 LEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQ 657
Query: 700 LLKCTDKEVLASLEQKLK-EIDEECRGEESRRVDLELSIMEVKDNLKK 746
LK ++E LEQ+LK E +EE R +E + E + +K + K
Sbjct: 658 RLKREEEE--ERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPK 703
Score = 37.7 bits (86), Expect = 0.043
Identities = 30/93 (32%), Positives = 52/93 (55%), Gaps = 9/93 (9%)
Query: 647 LRVTSAEIKLGKNRTEAEVKRYTEEK--ERLEKKKEEIRGHLA-----QLRKEKRELKET 699
L++ E + + R E +++R EE+ +RL++++EE R QLR+E+ E +E
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ 548
Query: 700 LLKCTDKEVLAS--LEQKLKEIDEECRGEESRR 730
LLK +++ L EQ+LK EE R + +R
Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKR 581
Score = 35.8 bits (81), Expect = 0.16
Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 7/76 (9%)
Query: 662 EAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDE 721
E KR +E ER +KK+E++ QL +E+RE + + ++E E++L++ +E
Sbjct: 1006 EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKR----RLQERERQYREEEELQQEEE 1061
Query: 722 ECRGEE---SRRVDLE 734
+ GEE RR +LE
Sbjct: 1062 QLLGEERETRRRQELE 1077
Score = 35.4 bits (80), Expect = 0.22
Identities = 29/91 (31%), Positives = 49/91 (53%), Gaps = 4/91 (4%)
Query: 644 KDRLRVTSAEIKLGKNRTEAEVKRYTEE-KERLEKKKEEIRGHLAQLRKEKRELKETLLK 702
+++L E +L + R E +KR EE +++L K++EE R +L++E+ E E LK
Sbjct: 546 REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQ--RLKREQEERLEQRLK 603
Query: 703 CTDKEVLASLEQKLKEIDEECRGEESRRVDL 733
+ E L E++ + + E EE RR L
Sbjct: 604 REEVERLEQEERREQRLKRE-EPEEERRQQL 633
Score = 34.3 bits (77), Expect = 0.48
Identities = 23/94 (24%), Positives = 52/94 (55%), Gaps = 6/94 (6%)
Query: 639 ASPPVKDRLRVTSAEIKLGKNRTEAEV--KRYTEEKERLEKKKEEIRGHLAQLRKEKREL 696
A P ++++LR ++ + + E KR +E+ER +++E+++ QL +E+RE
Sbjct: 891 AKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREK 950
Query: 697 KETLLKCTDKEVLASLEQKLKEIDEECRGEESRR 730
+ + ++E ++KL++ +E+ GEE +
Sbjct: 951 R----RRQERERQYRKDKKLQQKEEQLLGEEPEK 980
Score = 34.3 bits (77), Expect = 0.48
Identities = 26/83 (31%), Positives = 44/83 (53%), Gaps = 4/83 (4%)
Query: 670 EEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLAS--LEQKLK--EIDEECRG 725
+E +R ++K +E + L + R+EKR +ET K ++E L EQ L+ E D + R
Sbjct: 1305 KEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE 1364
Query: 726 EESRRVDLELSIMEVKDNLKKAE 748
EE R + +E + L++ E
Sbjct: 1365 EELRHQEQGRKFLEEEQRLRRQE 1387
Score = 33.9 bits (76), Expect = 0.63
Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 10/100 (10%)
Query: 653 EIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRK------EKRELKETLLKCTDK 706
E K + R E +KR EE+ K++EE H + RK ++ E +E LK ++
Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEE 494
Query: 707 EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
E E++ +++ R E+ R + L E ++ L++
Sbjct: 495 ERREQQERR----EQQLRREQEERREQRLKRQEEEERLQQ 530
Score = 32.3 bits (72), Expect = 1.8
Identities = 24/85 (28%), Positives = 44/85 (51%), Gaps = 11/85 (12%)
Query: 660 RTEAEVKRYTEE---------KERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLA 710
R E +++R EE +E+ E+++++ QLR+E+ E +E L+ +E
Sbjct: 301 RREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE--E 358
Query: 711 SLEQKLKEIDEECRGEESRRVDLEL 735
EQ+L+ EE R E+ R + +L
Sbjct: 359 RREQQLRREQEEERREQQLRREQQL 383
Score = 32.0 bits (71), Expect = 2.4
Identities = 23/93 (24%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
Query: 654 IKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLE 713
+K + R + +KR EE+ K+EE+ + R+E+R +E + +++L S E
Sbjct: 579 LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEE 638
Query: 714 QKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
Q+ + ++ R E+ R + L E ++ L++
Sbjct: 639 QEERR-QQQLRREQQERREQRLKREEEEERLEQ 670
Score = 31.2 bits (69), Expect = 4.1
Identities = 22/96 (22%), Positives = 52/96 (54%), Gaps = 5/96 (5%)
Query: 658 KNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRK---EKRELKETLLKCTDKEVLASLEQ 714
K R + K+Y EE+E +++++ +R + R+ E++ K+ L+ ++++L +
Sbjct: 980 KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREERE 1039
Query: 715 K--LKEIDEECRGEESRRVDLELSIMEVKDNLKKAE 748
K L+E + + R EE + + E + E ++ ++ E
Sbjct: 1040 KRRLQERERQYREEEELQQEEEQLLGEERETRRRQE 1075
Score = 30.8 bits (68), Expect = 5.3
Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 4/73 (5%)
Query: 662 EAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKE----TLLKCTDKEVLASLEQKLK 717
E KR +E+ER +++EE++ QL +E+RE + ++EV EQ L+
Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155
Query: 718 EIDEECRGEESRR 730
E E+ R +E R
Sbjct: 1156 EEPEKRRRQELER 1168
Score = 30.4 bits (67), Expect = 6.9
Identities = 24/80 (30%), Positives = 44/80 (55%), Gaps = 4/80 (5%)
Query: 660 RTEAEVKRYTEE--KERLEKKKEEIRGH--LAQLRKEKRELKETLLKCTDKEVLASLEQK 715
+ E E +R+ +E K++L++ +EE R L +E+RE +E + +E EQ+
Sbjct: 459 KREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQR 518
Query: 716 LKEIDEECRGEESRRVDLEL 735
LK +EE R ++ R + +L
Sbjct: 519 LKRQEEEERLQQRLRSEQQL 538
>gi|11119430 testis-specific kinase substrate [Homo sapiens]
Length = 592
Score = 42.4 bits (98), Expect = 0.002
Identities = 43/173 (24%), Positives = 76/173 (43%), Gaps = 27/173 (15%)
Query: 592 NLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPPSCP---------DAVVATPPGASPP 642
N+ L ++EP D + +TV+ + Q ++ PP+ P D S
Sbjct: 81 NVSLLNLAAMEPTDSTGTDSTVEDLSGQLTLAGPPASPTLPWDPDDADITEILSGVNSGL 140
Query: 643 VKDRLRVTSAEIKLGK-----NRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRK------ 691
V+ + +TS + K + ++E +E ER ++ EE+ G+ QL++
Sbjct: 141 VRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVT 200
Query: 692 ---EKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVK 741
E E+K +LK A LE+KL+ + ++ + E RR + EL E K
Sbjct: 201 RSVEDAEIKTNVLKQNS----ALLEEKLRYLQQQLQDETPRRQEAELQEPEEK 249
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/139 (23%), Positives = 63/139 (45%), Gaps = 11/139 (7%)
Query: 654 IKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDK------E 707
+K +++ EA K++ EEK+ LE+K ++ + + +ELK + T + E
Sbjct: 938 VKAEQSQQEA-AKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEE 996
Query: 708 VLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLENVS 767
+L +L++ L + +++ +G L + E++ KA+A T D +
Sbjct: 997 ILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQ----TAEDAMQIMEQM 1052
Query: 768 PRPKAVTPASAPDCTPVNS 786
+ K T AS D N+
Sbjct: 1053 TKEKTETLASLEDTKQTNA 1071
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/139 (23%), Positives = 63/139 (45%), Gaps = 11/139 (7%)
Query: 654 IKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDK------E 707
+K +++ EA K++ EEK+ LE+K ++ + + +ELK + T + E
Sbjct: 973 VKAEQSQQEA-AKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEE 1031
Query: 708 VLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLENVS 767
+L +L++ L + +++ +G L + E++ KA+A T D +
Sbjct: 1032 ILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQ----TAEDAMQIMEQM 1087
Query: 768 PRPKAVTPASAPDCTPVNS 786
+ K T AS D N+
Sbjct: 1088 TKEKTETLASLEDTKQTNA 1106
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 41.6 bits (96), Expect = 0.003
Identities = 41/172 (23%), Positives = 70/172 (40%), Gaps = 21/172 (12%)
Query: 550 PSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLESLEPEDPSLR 609
P + A ++ + L E+ GP P P + E + +S P P++
Sbjct: 49 PDTPPAMKNATSSKQLPLEPESPSGQVGPRPAPPQ------EESPSSEAKSRGPTPPAMG 102
Query: 610 ITTVKIQTEQQRISFPP--SCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNRTEAEVKR 667
R + PP S + A P SPP K ++ KL K R E K
Sbjct: 103 ----------PRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERAKY 152
Query: 668 YTEEKERLEKKKEEIRG-HLAQLRKEKRELKETLLKCTDKEVLASLEQKLKE 718
+K +K+E+ + QL++ +R L+E LK + A+LE++ ++
Sbjct: 153 LAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQRR--AALEERQRQ 202
Score = 40.0 bits (92), Expect = 0.009
Identities = 53/203 (26%), Positives = 76/203 (37%), Gaps = 21/203 (10%)
Query: 550 PSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLESLEPEDPSLR 609
P S + +SP + EA + S GP + N E + P+
Sbjct: 494 PPSPRGTTASPK-GRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPS 552
Query: 610 ITTVKIQTEQQRISFPPSCPDAVVATPPGASPPV---KDRLRVTSAEIK---LGKNRTEA 663
T Q EQ P AV+ +PP +PPV K T E L + R +A
Sbjct: 553 PTPAPPQKEQPPAETPTDA--AVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQA 610
Query: 664 EVKRYTEEKERLEKKKEEIRGHLAQLRKE------------KRELKETLLKCTDKEVLAS 711
+R EE+ER + + + R QL +E +RE +E K ++
Sbjct: 611 REQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQE 670
Query: 712 LEQKLKEIDEECRGEESRRVDLE 734
QK KE E EE+ R LE
Sbjct: 671 RLQKQKEEAEARSREEAERQRLE 693
Score = 35.8 bits (81), Expect = 0.16
Identities = 51/238 (21%), Positives = 89/238 (37%), Gaps = 17/238 (7%)
Query: 507 DLSELTAAVEPTEEATPVADDPNERESDRVYLDLTPVKSFLHGPSSAQAQASSPTLSC-L 565
+ E +A P +++ NE+ES +P S P+ A Q P
Sbjct: 513 EAKESPSAAGPEDKSQSKRRASNEKESAA---PASPAPSPAPSPTPAPPQKEQPPAETPT 569
Query: 566 DNATEALPADSGPGPTPDEPCIKCPEN------LGEQQLESLEP-----EDPSLRITTVK 614
D A P P TP +P + L E++ ++ E ++ L+ K
Sbjct: 570 DAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERDK 629
Query: 615 IQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEI-KLGKNRTEAEVKRYTEEKE 673
E+Q + + +++ + E +L K + EAE R EE E
Sbjct: 630 RMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEA-RSREEAE 688
Query: 674 RLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRV 731
R ++E+ Q R+E+R+ E ++K T K ++ +QK + G V
Sbjct: 689 RQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPV 746
Score = 30.0 bits (66), Expect = 9.0
Identities = 48/195 (24%), Positives = 74/195 (37%), Gaps = 36/195 (18%)
Query: 635 TPPGASPPVKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKR 694
T P A+ PV R S R+ V R ER E++K G A +R+
Sbjct: 352 THPSAAVPVCPRSASASPLTPCSVTRS---VHRCAPAGERGERRKPNAGGSPAPVRRRPE 408
Query: 695 ELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEAGPVTL 754
AS QK ++ D+E E+ E S + + +LKK ++ P +
Sbjct: 409 ---------------ASPVQKKEKKDKERENEK------EKSALARERSLKKRQSLPASP 447
Query: 755 GTTVDTTHLENVSPRPKAVTPAS--------APDCTPVNSATTLKNRPLS---VVVTGKG 803
+ + +SP+ KA P+S A C TL +P S + KG
Sbjct: 448 RARLSASTASELSPKSKA-RPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKG 506
Query: 804 TVLQKAKEWEKKGAS 818
V +K + E A+
Sbjct: 507 RVRRKEEAKESPSAA 521
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 41.2 bits (95), Expect = 0.004
Identities = 31/113 (27%), Positives = 57/113 (50%), Gaps = 19/113 (16%)
Query: 645 DRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCT 704
D L +T A+++ K+ TE +VK TEE L++ +A+L KEK+ L+E +
Sbjct: 955 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEI-------IAKLTKEKKALQEAHQQAL 1007
Query: 705 DK------------EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLK 745
D + LEQ++ +++ E+ R+DLE + +++ +LK
Sbjct: 1008 DDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Score = 33.1 bits (74), Expect = 1.1
Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 687 AQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
A+ KE +KE + KE L E + KE++E+ + DL+L + +DNL
Sbjct: 843 AEREKEMASMKEEFTRL--KEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLAD 900
Query: 747 AE 748
AE
Sbjct: 901 AE 902
Score = 32.7 bits (73), Expect = 1.4
Identities = 25/92 (27%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 666 KRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKC-TDKEVLASLEQKLKEIDEECR 724
++Y E + LE ++E R +L K K +E+L T K +L++++ ++ E+
Sbjct: 1458 QKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLG 1517
Query: 725 GE-------ESRRVDLELSIMEVKDNLKKAEA 749
E R LE ME++ L++AEA
Sbjct: 1518 SSGKTIHELEKVRKQLEAEKMELQSALEEAEA 1549
Score = 32.3 bits (72), Expect = 1.8
Identities = 52/250 (20%), Positives = 91/250 (36%), Gaps = 34/250 (13%)
Query: 507 DLSELTAAVEPTEEATPVADDPNERESDRVYLDLTPVKSFLHGPSSAQAQASSPTLSCLD 566
+L EL A VE TE + +A+ S+RV L + S ++ A S +
Sbjct: 1684 ELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEE 1743
Query: 567 NATEALPADSGPGPTPDEPCIKCPENLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPP 626
E A+ E K + E + +D S + +K EQ
Sbjct: 1744 AVQECRNAE--------EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH 1795
Query: 627 SCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHL 686
+A G K +L+ A ++ +N EAE KR E ++G
Sbjct: 1796 RLDEAEQIALKGG----KKQLQKLEARVRELENELEAEQKR----------NAESVKG-- 1839
Query: 687 AQLRKEKRELKETLLKCTD--------KEVLASLEQKLKEIDEECRGEESRRVDLELSIM 738
+RK +R +KE + + ++++ L+ K+K + E +
Sbjct: 1840 --MRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFR 1897
Query: 739 EVKDNLKKAE 748
+V+ L +AE
Sbjct: 1898 KVQHELDEAE 1907
Score = 31.6 bits (70), Expect = 3.1
Identities = 20/84 (23%), Positives = 46/84 (54%), Gaps = 2/84 (2%)
Query: 658 KNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLK 717
KN + +V+ + E++ +++ + QL + +E+ E L ++E+ A L K +
Sbjct: 884 KNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLED--EEEMNAELTAKKR 941
Query: 718 EIDEECRGEESRRVDLELSIMEVK 741
++++EC + DLEL++ +V+
Sbjct: 942 KLEDECSELKRDIDDLELTLAKVE 965
>gi|50083279 centrosome protein 4 [Homo sapiens]
Length = 1140
Score = 41.2 bits (95), Expect = 0.004
Identities = 31/109 (28%), Positives = 58/109 (53%), Gaps = 5/109 (4%)
Query: 651 SAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKE-VL 709
+A+ +LG+ + E+KR E + LE+ +++ L +KEK L + LL +D E V+
Sbjct: 339 TADKELGE--AKKEIKRKLSEMQDLEETMAKLQLELNLCQKEKERLSDELLVKSDLETVV 396
Query: 710 ASLEQKLKEIDE--ECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGT 756
LEQ+ + + + E R++ LE+ M ++ +K+ + P L T
Sbjct: 397 HQLEQEKQRLSKKVESFAVTERQLTLEVERMRLEHGIKRRDRSPSRLDT 445
Score = 30.0 bits (66), Expect = 9.0
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Query: 672 KERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLK 717
K LEK E + QL EK ELK +L KE + SLE KLK
Sbjct: 603 KSELEKTIEHLTCVNHQLESEKYELKSKVL--IMKETIESLENKLK 646
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 41.2 bits (95), Expect = 0.004
Identities = 32/117 (27%), Positives = 57/117 (48%), Gaps = 16/117 (13%)
Query: 639 ASPPVKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKE 698
+SP + D+L+ + E++ N E ++ + +E + K +E++ L + + E E ++
Sbjct: 275 SSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEK 334
Query: 699 TLLKCTDKEV------------LASLEQKLKEIDEEC----RGEESRRVDLELSIME 739
L KC D+ V +LEQKLK++ E+ + ES R LE I E
Sbjct: 335 VLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKE 391
Score = 37.0 bits (84), Expect = 0.074
Identities = 24/96 (25%), Positives = 51/96 (53%)
Query: 653 EIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASL 712
++K R + ++K + ++LE++KE ++ L+QL+ + + K + T + L +
Sbjct: 2783 QLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTE 2842
Query: 713 EQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAE 748
++LKE EE E +D S++ + L+KA+
Sbjct: 2843 IKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAK 2878
Score = 30.4 bits (67), Expect = 6.9
Identities = 23/75 (30%), Positives = 41/75 (54%), Gaps = 6/75 (8%)
Query: 674 RLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDL 733
R +K +E+ G L +L+KEK++ + L D A +QK K +E+ G +R +
Sbjct: 15 RALQKIQELEGQLDKLKKEKQQRQFQL----DSLEAALQKQKQKVENEKTEGTNLKRENQ 70
Query: 734 ELSIMEVKDNLKKAE 748
L ME+ ++L+K +
Sbjct: 71 RL--MEICESLEKTK 83
>gi|14589862 aspartate beta-hydroxylase isoform d [Homo sapiens]
Length = 210
Score = 40.8 bits (94), Expect = 0.005
Identities = 31/92 (33%), Positives = 53/92 (57%), Gaps = 5/92 (5%)
Query: 656 LGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQK 715
+ K +T+A+VK T+E+ + EK+K E R ++ + K+ KE + K DK++ A +
Sbjct: 84 VAKRKTKAKVKELTKEELKKEKEKPESRKE-SKNEERKKGKKEDVRK--DKKI-ADADLS 139
Query: 716 LKEIDEECRGEESRRVDLELSIMEVKDNLKKA 747
KE + + E +VDLE S + K+N KK+
Sbjct: 140 RKESPKGKKDREKEKVDLEKS-AKTKENRKKS 170
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.127 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,212,729
Number of Sequences: 37866
Number of extensions: 1832318
Number of successful extensions: 12072
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 125
Number of HSP's successfully gapped in prelim test: 638
Number of HSP's that attempted gapping in prelim test: 9524
Number of HSP's gapped (non-prelim): 2869
length of query: 818
length of database: 18,247,518
effective HSP length: 111
effective length of query: 707
effective length of database: 14,044,392
effective search space: 9929385144
effective search space used: 9929385144
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.