Guide to the Human Genome
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Search of human proteins with 50897850

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|50897850 KIAA1914 protein isoform 1 [Homo sapiens]
         (818 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50897850 KIAA1914 protein isoform 1 [Homo sapiens]                1636   0.0  
gi|24308338 KIAA1914 protein isoform 2 [Homo sapiens]                1623   0.0  
gi|197382472 actin filament associated protein 1 isoform a [Homo...   448   e-126
gi|40807504 actin filament associated protein 1 [Homo sapiens]        349   5e-96
gi|226437595 actin filament associated protein 1-like 1 isoform ...   312   7e-85
gi|55742689 actin filament associated protein 1-like 1 isoform 1...   312   7e-85
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap...    54   4e-07
gi|88501740 TRIO and F-actin binding protein isoform 1 [Homo sap...    54   4e-07
gi|88501741 TRIO and F-actin binding protein isoform 2 [Homo sap...    50   8e-06
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    46   1e-04
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    46   1e-04
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]            46   2e-04
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...    45   2e-04
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ...    45   3e-04
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...    43   0.001
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...    43   0.001
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho...    43   0.001
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho...    43   0.001
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho...    43   0.001
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho...    43   0.001
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...    43   0.001
gi|148746195 trichohyalin [Homo sapiens]                               42   0.002
gi|11119430 testis-specific kinase substrate [Homo sapiens]            42   0.002
gi|38044112 restin isoform b [Homo sapiens]                            42   0.002
gi|4506751 restin isoform a [Homo sapiens]                             42   0.002
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    42   0.003
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    41   0.004
gi|50083279 centrosome protein 4 [Homo sapiens]                        41   0.004
gi|55770834 centromere protein F [Homo sapiens]                        41   0.004
gi|14589862 aspartate beta-hydroxylase isoform d [Homo sapiens]        41   0.005

>gi|50897850 KIAA1914 protein isoform 1 [Homo sapiens]
          Length = 818

 Score = 1636 bits (4237), Expect = 0.0
 Identities = 818/818 (100%), Positives = 818/818 (100%)

Query: 1   MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKV 60
           MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKV
Sbjct: 1   MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKV 60

Query: 61  TINKQQNAESQGKAPEEQGLLPNGEPSQHSSAPQKSLPDLPPPKMIPERKQLAIPKTESP 120
           TINKQQNAESQGKAPEEQGLLPNGEPSQHSSAPQKSLPDLPPPKMIPERKQLAIPKTESP
Sbjct: 61  TINKQQNAESQGKAPEEQGLLPNGEPSQHSSAPQKSLPDLPPPKMIPERKQLAIPKTESP 120

Query: 121 EGYYEEAEPYDTSLNEDGEAVSSSYESYDEEDGSKGKSAPYQWPSPEAGIELMRDARICA 180
           EGYYEEAEPYDTSLNEDGEAVSSSYESYDEEDGSKGKSAPYQWPSPEAGIELMRDARICA
Sbjct: 121 EGYYEEAEPYDTSLNEDGEAVSSSYESYDEEDGSKGKSAPYQWPSPEAGIELMRDARICA 180

Query: 181 FLWRKKWLGQWAKQLCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLK 240
           FLWRKKWLGQWAKQLCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLK
Sbjct: 181 FLWRKKWLGQWAKQLCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLK 240

Query: 241 ITPMNADVIVLGLQSKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEK 300
           ITPMNADVIVLGLQSKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEK
Sbjct: 241 ITPMNADVIVLGLQSKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEK 300

Query: 301 YLSASEYGSSVDGHPEVPETKDVKKKCSAGLKLSNLMNLGRKKSTSLEPVERSLETSSYL 360
           YLSASEYGSSVDGHPEVPETKDVKKKCSAGLKLSNLMNLGRKKSTSLEPVERSLETSSYL
Sbjct: 301 YLSASEYGSSVDGHPEVPETKDVKKKCSAGLKLSNLMNLGRKKSTSLEPVERSLETSSYL 360

Query: 361 NVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSPDHLYSFRILHK 420
           NVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSPDHLYSFRILHK
Sbjct: 361 NVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSPDHLYSFRILHK 420

Query: 421 GEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSLLLMQ 480
           GEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSLLLMQ
Sbjct: 421 GEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSLLLMQ 480

Query: 481 RKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVADDPNERESDRVYLDL 540
           RKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVADDPNERESDRVYLDL
Sbjct: 481 RKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVADDPNERESDRVYLDL 540

Query: 541 TPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLES 600
           TPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLES
Sbjct: 541 TPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLES 600

Query: 601 LEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNR 660
           LEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNR
Sbjct: 601 LEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNR 660

Query: 661 TEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEID 720
           TEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEID
Sbjct: 661 TEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEID 720

Query: 721 EECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLENVSPRPKAVTPASAPD 780
           EECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLENVSPRPKAVTPASAPD
Sbjct: 721 EECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLENVSPRPKAVTPASAPD 780

Query: 781 CTPVNSATTLKNRPLSVVVTGKGTVLQKAKEWEKKGAS 818
           CTPVNSATTLKNRPLSVVVTGKGTVLQKAKEWEKKGAS
Sbjct: 781 CTPVNSATTLKNRPLSVVVTGKGTVLQKAKEWEKKGAS 818


>gi|24308338 KIAA1914 protein isoform 2 [Homo sapiens]
          Length = 814

 Score = 1623 bits (4202), Expect = 0.0
 Identities = 814/818 (99%), Positives = 814/818 (99%), Gaps = 4/818 (0%)

Query: 1   MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKV 60
           MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKV
Sbjct: 1   MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKV 60

Query: 61  TINKQQNAESQGKAPEEQGLLPNGEPSQHSSAPQKSLPDLPPPKMIPERKQLAIPKTESP 120
           TINKQQNAESQGKAPEEQGLLPNGEPSQHSSAPQKSLPDLPPPKMIPERKQLAIPKTESP
Sbjct: 61  TINKQQNAESQGKAPEEQGLLPNGEPSQHSSAPQKSLPDLPPPKMIPERKQLAIPKTESP 120

Query: 121 EGYYEEAEPYDTSLNEDGEAVSSSYESYDEEDGSKGKSAPYQWPSPEAGIELMRDARICA 180
           EGYYEEAEPYDTSLNEDGEAVSSSYESYDEEDGSKGKSAPYQWPSPEAGIELMRDARICA
Sbjct: 121 EGYYEEAEPYDTSLNEDGEAVSSSYESYDEEDGSKGKSAPYQWPSPEAGIELMRDARICA 180

Query: 181 FLWRKKWLGQWAKQLCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLK 240
           FLWRKKWLGQWAKQLCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLK
Sbjct: 181 FLWRKKWLGQWAKQLCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLK 240

Query: 241 ITPMNADVIVLGLQSKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEK 300
           ITPMNADVIVLGLQSKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEK
Sbjct: 241 ITPMNADVIVLGLQSKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEK 300

Query: 301 YLSASEYGSSVDGHPEVPETKDVKKKCSAGLKLSNLMNLGRKKSTSLEPVERSLETSSYL 360
           YLSASEYGSSVDGHPEVPETKDVKKKCSAGLKLSNLMNLGRKKSTSLEPVERSLETSSYL
Sbjct: 301 YLSASEYGSSVDGHPEVPETKDVKKKCSAGLKLSNLMNLGRKKSTSLEPVERSLETSSYL 360

Query: 361 NVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSPDHLYSFRILHK 420
           NVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSPDHLYSFRILHK
Sbjct: 361 NVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSPDHLYSFRILHK 420

Query: 421 GEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSLLLMQ 480
           GEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSLLLMQ
Sbjct: 421 GEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSLLLMQ 480

Query: 481 RKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVADDPNERESDRVYLDL 540
           RKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVADDPNERESDRVYLDL
Sbjct: 481 RKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVADDPNERESDRVYLDL 540

Query: 541 TPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLES 600
           TPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLES
Sbjct: 541 TPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLES 600

Query: 601 LEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNR 660
           LEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNR
Sbjct: 601 LEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNR 660

Query: 661 TEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEID 720
           TEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEID
Sbjct: 661 TEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEID 720

Query: 721 EECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLENVSPRPKAVTPASAPD 780
           EECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLEN    PKAVTPASAPD
Sbjct: 721 EECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLEN----PKAVTPASAPD 776

Query: 781 CTPVNSATTLKNRPLSVVVTGKGTVLQKAKEWEKKGAS 818
           CTPVNSATTLKNRPLSVVVTGKGTVLQKAKEWEKKGAS
Sbjct: 777 CTPVNSATTLKNRPLSVVVTGKGTVLQKAKEWEKKGAS 814


>gi|197382472 actin filament associated protein 1 isoform a [Homo
           sapiens]
          Length = 814

 Score =  448 bits (1153), Expect = e-126
 Identities = 322/867 (37%), Positives = 455/867 (52%), Gaps = 108/867 (12%)

Query: 7   LEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKVTINKQQ 66
           +E+L+ EL  FL++LD E L+ST   KK+ +  +L     S   D       K    KQ+
Sbjct: 1   MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDV------KDHAQKQE 54

Query: 67  NAESQGKAPEEQGLLPNGEPSQHSSAPQKSLPDLPPPKMIPERKQLAIPKTESPEGYYEE 126
            A S          LP        + PQ  LP++P P + P+     +P +  PEGYYEE
Sbjct: 55  TANS----------LP--------APPQMPLPEIPQPWLPPDSGPPPLPTSSLPEGYYEE 96

Query: 127 AEP--------YDTSLNEDGEAVSSSYESYDEED-GSKGKSAPYQWPSPEAGIELMRDAR 177
           A P        Y TS N D +A+SSSYESYDEE+   KGK   +QWPS EA ++L++DA+
Sbjct: 97  AVPLSPGKAPEYITS-NYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAK 155

Query: 178 ICAFLWRKKWLGQWAKQLCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEH 237
           ICAFL RKK  GQW K LCVIKD +LLCYKSSKD  PQ+++ L G ++ +  K  +KK+H
Sbjct: 156 ICAFLLRKKRFGQWTKLLCVIKDTKLLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKH 215

Query: 238 KLKITPMNADVIVLGLQSKDQAEQWLRVIQEV-SGLPSEGASEGNQYTPDAQRFNCQKPD 296
           +LKIT    D +VL +QSK+QAEQWL+VI+E  SG      SE     P        K +
Sbjct: 216 ELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDSE----CPPPPSSPVHKAE 271

Query: 297 IAEKYLSASEYGSSVDGHPEVPET-----KDVKKKCSA------------GLKLSNLMNL 339
           + EK LS+    S  +G  E   T     + VK+K S+            G K++ +++L
Sbjct: 272 L-EKKLSSERPSSDGEGVVENGITTCNGKEQVKRKKSSKSEAKGTVSKVTGKKITKIISL 330

Query: 340 GRKKSTSLE---PVERSLETSSYLNVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPL 396
           G+KK ++ E     E  + T  YLNVL NS+W+ RWC V+DN L F++DR   K     +
Sbjct: 331 GKKKPSTDEQTSSAEEDVPTCGYLNVLSNSRWRERWCRVKDNKLIFHKDRTDLKTHIVSI 390

Query: 397 SLVGCEVVPDPSPDHLYSFRILHKGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFT 456
            L GCEV+P     H  +FR+L  G+E+A LEA SSE+MG W+G+LL+E+GS TDPE   
Sbjct: 391 PLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALH 450

Query: 457 YDYVDADRVSCIVSAAKNSLLLMQRKFSEPNTYIDGLPSQDRQEE----LYDDVDLSELT 512
           YDY+D +  + ++  AK +   M R+    N Y+ G  +           YDDV    + 
Sbjct: 451 YDYIDVEMSASVIQTAKQTFCFMNRRVISANPYLGGTSNGYAHPSGTALHYDDVPC--IN 508

Query: 513 AAVEPTEEATPVADDPNERE-----SDRVYLDLTPVKSFLHGPSSAQAQASSPTLSCLDN 567
            + EP E+  P +      E     +  +Y +L P   F    S A  +AS  +   L +
Sbjct: 509 GSWEP-EDGFPASCSRGLGEEVLYDNAGLYDNLPPPHIFAR-YSPADRKASRLSADKLSS 566

Query: 568 ATEALPADSGPGPTPDEPCIKCPENLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPPS 627
                PA S    T      +    L   QL+  +P   S  +T      + + +S  P 
Sbjct: 567 NHYKYPA-SAQSVTNTSSVGRASLGL-NSQLKGKKPPVASNGVT-----GKGKTLSSQPK 619

Query: 628 CPDAVVATPPGASPPVKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLA 687
             D      P A   V  R    +A+ K GKNR EA+ KR   ++E L K+KE +R  LA
Sbjct: 620 KAD------PAA---VVKRTGSNAAQYKYGKNRVEADAKRLQTKEEELLKRKEALRNRLA 670

Query: 688 QLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKA 747
           QLRKE+++L+  +     ++  A LE+KLK+++EECR +E+ RV LEL + EVK++LKKA
Sbjct: 671 QLRKERKDLRAAIEVNAGRKPQAILEEKLKQLEEECRQKEAERVSLELELTEVKESLKKA 730

Query: 748 EAGPVTLGTTVD----TTHLENVSPRPKAVTPASAPDC--------TPVNSATTLKNRPL 795
            AG VTLG  ++    T+  ++   R + +  +    C         PVNSA  LK    
Sbjct: 731 LAGGVTLGLAIEPKSGTSSPQSPVFRHRTLENSPISSCDTSDTEGPVPVNSAAVLKK--- 787

Query: 796 SVVVTG----KGTVLQKAKEWEKKGAS 818
           S    G    +G VL+KAKEWE K  +
Sbjct: 788 SQAAPGSSPCRGHVLRKAKEWELKNGT 814


>gi|40807504 actin filament associated protein 1 [Homo sapiens]
          Length = 730

 Score =  349 bits (896), Expect = 5e-96
 Identities = 212/516 (41%), Positives = 293/516 (56%), Gaps = 60/516 (11%)

Query: 7   LEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKVTINKQQ 66
           +E+L+ EL  FL++LD E L+ST   KK+ +  +L     S   D       K    KQ+
Sbjct: 1   MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDV------KDHAQKQE 54

Query: 67  NAESQGKAPEEQGLLPNGEPSQHSSAPQKSLPDLPPPKMIPERKQLAIPKTESPEGYYEE 126
            A S          LP        + PQ  LP++P P + P+     +P +  PEGYYEE
Sbjct: 55  TANS----------LP--------APPQMPLPEIPQPWLPPDSGPPPLPTSSLPEGYYEE 96

Query: 127 AEP--------YDTSLNEDGEAVSSSYESYDEED-GSKGKSAPYQWPSPEAGIELMRDAR 177
           A P        Y TS N D +A+SSSYESYDEE+   KGK   +QWPS EA ++L++DA+
Sbjct: 97  AVPLSPGKAPEYITS-NYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAK 155

Query: 178 ICAFLWRKKWLGQWAKQLCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEH 237
           ICAFL RKK  GQW K LCVIKD +LLCYKSSKD  PQ+++ L G ++ +  K  +KK+H
Sbjct: 156 ICAFLLRKKRFGQWTKLLCVIKDTKLLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKH 215

Query: 238 KLKITPMNADVIVLGLQSKDQAEQWLRVIQEV-SGLPSEGASEGNQYTPDAQRFNCQKPD 296
           +LKIT    D +VL +QSK+QAEQWL+VI+E  SG      SE     P        K +
Sbjct: 216 ELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDSE----CPPPPSSPVHKAE 271

Query: 297 IAEKYLSASEYGSSVDGHPEVPET-----KDVKKKCSA------------GLKLSNLMNL 339
           + EK LS+    S  +G  E   T     + VK+K S+            G K++ +++L
Sbjct: 272 L-EKKLSSERPSSDGEGVVENGITTCNGKEQVKRKKSSKSEAKGTVSKVTGKKITKIISL 330

Query: 340 GRKKSTSLE---PVERSLETSSYLNVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPL 396
           G+KK ++ E     E  + T  YLNVL NS+W+ RWC V+DN L F++DR   K     +
Sbjct: 331 GKKKPSTDEQTSSAEEDVPTCGYLNVLSNSRWRERWCRVKDNKLIFHKDRTDLKTHIVSI 390

Query: 397 SLVGCEVVPDPSPDHLYSFRILHKGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFT 456
            L GCEV+P     H  +FR+L  G+E+A LEA SSE+MG W+G+LL+E+GS TDPE   
Sbjct: 391 PLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALH 450

Query: 457 YDYVDADRVSCIVSAAKNSLLLMQRKFSEPNTYIDG 492
           YDY+D +  + ++  AK +   M R+    N Y+ G
Sbjct: 451 YDYIDVEMSASVIQTAKQTFCFMNRRVISANPYLGG 486



 Score =  122 bits (306), Expect = 1e-27
 Identities = 80/200 (40%), Positives = 114/200 (57%), Gaps = 20/200 (10%)

Query: 636 PPGASPP-VKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKR 694
           P  A P  V  R    +A+ K GKNR EA+ KR   ++E L K+KE +R  LAQLRKE++
Sbjct: 534 PKKADPAAVVKRTGSNAAQYKYGKNRVEADAKRLQTKEEELLKRKEALRNRLAQLRKERK 593

Query: 695 ELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEAGPVTL 754
           +L+  +     ++  A LE+KLK+++EECR +E+ RV LEL + EVK++LKKA AG VTL
Sbjct: 594 DLRAAIEVNAGRKPQAILEEKLKQLEEECRQKEAERVSLELELTEVKESLKKALAGGVTL 653

Query: 755 GTTVD----TTHLENVSPRPKAVTPASAPDC--------TPVNSATTLKNRPLSVVVTG- 801
           G  ++    T+  ++   R + +  +    C         PVNSA  LK    S    G 
Sbjct: 654 GLAIEPKSGTSSPQSPVFRHRTLENSPISSCDTSDTEGPVPVNSAAVLKK---SQAAPGS 710

Query: 802 ---KGTVLQKAKEWEKKGAS 818
              +G VL+KAKEWE K  +
Sbjct: 711 SPCRGHVLRKAKEWELKNGT 730


>gi|226437595 actin filament associated protein 1-like 1 isoform 2
           [Homo sapiens]
          Length = 725

 Score =  312 bits (800), Expect = 7e-85
 Identities = 214/575 (37%), Positives = 303/575 (52%), Gaps = 81/575 (14%)

Query: 1   MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKV 60
           M+R + LEQLL EL   L +LD E LS T L KK  +A +L+      + +  Y+Y+N  
Sbjct: 1   MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA 60

Query: 61  TINKQQN------------AESQGKAPEEQGLLPNGEPSQHSSAPQ-KSLPDLPPP---K 104
            ++   +                   PE+ G    G   + + +P+ ++  DLPPP   K
Sbjct: 61  DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK 120

Query: 105 MIPE---RKQLAIPKTESPE----------------GYYEEAEPYDTSLNEDGE------ 139
             PE    + L +   +SPE                GYYE+A+    +   +GE      
Sbjct: 121 PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN 180

Query: 140 ---AVSSSYESYDEEDGSKGKSAP--YQWPSPEAGIELMRDARICAFLWRKKWLGQWAKQ 194
              A+SSSYESYDEE+  +GKS    +QWPS EA + L+R+ RICAFL RKK  GQWAKQ
Sbjct: 181 DSDAMSSSYESYDEEE-EEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQ 239

Query: 195 LCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLKITPMNADVIVLGLQ 254
           L VI++++LLCYKSSKD  P L + L   S+I+  K  R K H+L+ T    +V+VL LQ
Sbjct: 240 LTVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQ 299

Query: 255 SKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEKYLSASEYGSSVD-- 312
           S++QAE+WL+VI+EVS     G +EG +  P +    C K D+ +K LS  +  S  D  
Sbjct: 300 SREQAEEWLKVIREVS--KPVGGAEGVE-VPRSPVLLC-KLDL-DKRLSQEKQTSDSDSV 354

Query: 313 ---------GHPEVPETKDVKKKC----------SAGLKLSNLMNLGRKKSTS----LEP 349
                    G  E  +    KK            +AG K++ ++   +KK+ +       
Sbjct: 355 GVGDNCSTLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSS 414

Query: 350 VERSLETSSYLNVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSP 409
            E  +    YLNVLVN  WK RWC ++ N L+F++D    +     ++L GCEV P   P
Sbjct: 415 TEEEVPCCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGP 474

Query: 410 DHLYSFRILHKGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIV 469
            H ++FRIL   +E+A LEA  SE+MG WLGLLL E GS+  PE   YDYVD + ++ IV
Sbjct: 475 RHPFAFRILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIV 534

Query: 470 SAAKNSLLL---MQRKFSEPNTYIDGLPSQDRQEE 501
           SA +NS L     Q ++ EP  Y D +P +  Q+E
Sbjct: 535 SAGRNSFLYARSCQNQWPEPRVY-DDVPYEKMQDE 568



 Score = 97.4 bits (241), Expect = 5e-20
 Identities = 53/121 (43%), Positives = 80/121 (66%), Gaps = 2/121 (1%)

Query: 641 PPVKDRLRVTSA-EIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKET 699
           P VK +   +SA + K GKNR E + +RY  EKE+LEK+KE IR  L  LR+EKRELKE 
Sbjct: 594 PQVKVKRHASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEA 653

Query: 700 LLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVD 759
            ++ +    L +LE+ +  ++ +CR +E RR+DLEL ++ VK+ L+++ AG   LG +V 
Sbjct: 654 -IRSSPGAKLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVS 712

Query: 760 T 760
           +
Sbjct: 713 S 713


>gi|55742689 actin filament associated protein 1-like 1 isoform 1
           [Homo sapiens]
          Length = 768

 Score =  312 bits (800), Expect = 7e-85
 Identities = 214/575 (37%), Positives = 303/575 (52%), Gaps = 81/575 (14%)

Query: 1   MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKV 60
           M+R + LEQLL EL   L +LD E LS T L KK  +A +L+      + +  Y+Y+N  
Sbjct: 1   MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA 60

Query: 61  TINKQQN------------AESQGKAPEEQGLLPNGEPSQHSSAPQ-KSLPDLPPP---K 104
            ++   +                   PE+ G    G   + + +P+ ++  DLPPP   K
Sbjct: 61  DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK 120

Query: 105 MIPE---RKQLAIPKTESPE----------------GYYEEAEPYDTSLNEDGE------ 139
             PE    + L +   +SPE                GYYE+A+    +   +GE      
Sbjct: 121 PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN 180

Query: 140 ---AVSSSYESYDEEDGSKGKSAP--YQWPSPEAGIELMRDARICAFLWRKKWLGQWAKQ 194
              A+SSSYESYDEE+  +GKS    +QWPS EA + L+R+ RICAFL RKK  GQWAKQ
Sbjct: 181 DSDAMSSSYESYDEEE-EEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQ 239

Query: 195 LCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLKITPMNADVIVLGLQ 254
           L VI++++LLCYKSSKD  P L + L   S+I+  K  R K H+L+ T    +V+VL LQ
Sbjct: 240 LTVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQ 299

Query: 255 SKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEKYLSASEYGSSVD-- 312
           S++QAE+WL+VI+EVS     G +EG +  P +    C K D+ +K LS  +  S  D  
Sbjct: 300 SREQAEEWLKVIREVS--KPVGGAEGVE-VPRSPVLLC-KLDL-DKRLSQEKQTSDSDSV 354

Query: 313 ---------GHPEVPETKDVKKKC----------SAGLKLSNLMNLGRKKSTS----LEP 349
                    G  E  +    KK            +AG K++ ++   +KK+ +       
Sbjct: 355 GVGDNCSTLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSS 414

Query: 350 VERSLETSSYLNVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSP 409
            E  +    YLNVLVN  WK RWC ++ N L+F++D    +     ++L GCEV P   P
Sbjct: 415 TEEEVPCCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGP 474

Query: 410 DHLYSFRILHKGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIV 469
            H ++FRIL   +E+A LEA  SE+MG WLGLLL E GS+  PE   YDYVD + ++ IV
Sbjct: 475 RHPFAFRILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIV 534

Query: 470 SAAKNSLLL---MQRKFSEPNTYIDGLPSQDRQEE 501
           SA +NS L     Q ++ EP  Y D +P +  Q+E
Sbjct: 535 SAGRNSFLYARSCQNQWPEPRVY-DDVPYEKMQDE 568



 Score =  127 bits (319), Expect = 4e-29
 Identities = 76/182 (41%), Positives = 111/182 (60%), Gaps = 16/182 (8%)

Query: 641 PPVKDRLRVTSA-EIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKET 699
           P VK +   +SA + K GKNR E + +RY  EKE+LEK+KE IR  L  LR+EKRELKE 
Sbjct: 594 PQVKVKRHASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEA 653

Query: 700 LLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVD 759
            ++ +    L +LE+ +  ++ +CR +E RR+DLEL ++ VK+ L+++ AG   LG    
Sbjct: 654 -IRSSPGAKLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGL--- 709

Query: 760 TTHLENVSPRPKAVTPASAPDCT------PVNSATTLKNRPLSVVVTGKGTVLQKAKEWE 813
                +VS +PK+   A+ P  +      PVN  + L+ R  S+V + +G VLQKAKEWE
Sbjct: 710 -----SVSSKPKSGETANKPQNSVPEQPLPVNCVSELRKRSPSIVASNQGRVLQKAKEWE 764

Query: 814 KK 815
            K
Sbjct: 765 MK 766


>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sapiens]
          Length = 2365

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 92/427 (21%), Positives = 156/427 (36%), Gaps = 46/427 (10%)

Query: 348  EPVERSLETSSYLNVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQ--QPLSLVGCEVVP 405
            EP   SL T+S       SQWK  W  + D+ L +Y+D    +  +    + L  C  V 
Sbjct: 1793 EPPSPSLTTTS------TSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVT 1846

Query: 406  DPSPDHLYSFRILHKGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRV 465
            + +    Y F+I H  + +  L A +S    +W+  L       + P+       + +  
Sbjct: 1847 EYAVQRNYGFQI-HTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKENA 1905

Query: 466  SCIVSAAKNSLLLMQRKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVA 525
                S  K  L   +++         G    D Q +  D V+LS LT A  P    TP  
Sbjct: 1906 LHSYSTQKGPLKAGEQRAGSEVISRGGPRKADGQRQALDYVELSPLTQA-SPQRARTPAR 1964

Query: 526  DDPNERESDRVYLDLTPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEP 585
                  + + +  DL           + +++         D+ T  +PA  GP      P
Sbjct: 1965 TPDRLAKQEELERDL-----------AQRSEERRKWFEATDSRTPEVPAGEGPRRGLGAP 2013

Query: 586  CIKCPEN-LGE------QQLESLE-PEDPSLRITTVKIQTEQQRISFPPSCPDAVVATP- 636
              +  +N L E      Q+LE L   E+  + +T +  Q+  +R   P    +A+     
Sbjct: 2014 LTEDQQNRLSEEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHEALEKEVQ 2073

Query: 637  -----------PGASPPVKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGH 685
                        G +P    R +     I  G    EA  +   E +   ++  EE++ H
Sbjct: 2074 ALRAQLEAWRLQGEAPQSALRSQ-EDGHIPPGYISQEACERSLAEMESSHQQVMEELQRH 2132

Query: 686  LAQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLK 745
              +  +  ++ KE LL        +++E   K   EE     SR +    S+ +  D L+
Sbjct: 2133 HERELQRLQQEKEWLLAEETAATASAIEAMKKAYQEEL----SRELSKTRSLQQGPDGLR 2188

Query: 746  KAEAGPV 752
            K     V
Sbjct: 2189 KQHQSDV 2195


>gi|88501740 TRIO and F-actin binding protein isoform 1 [Homo
           sapiens]
          Length = 652

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 92/427 (21%), Positives = 156/427 (36%), Gaps = 46/427 (10%)

Query: 348 EPVERSLETSSYLNVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQ--QPLSLVGCEVVP 405
           EP   SL T+S       SQWK  W  + D+ L +Y+D    +  +    + L  C  V 
Sbjct: 80  EPPSPSLTTTS------TSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVT 133

Query: 406 DPSPDHLYSFRILHKGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRV 465
           + +    Y F+I H  + +  L A +S    +W+  L       + P+       + +  
Sbjct: 134 EYAVQRNYGFQI-HTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKENA 192

Query: 466 SCIVSAAKNSLLLMQRKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVA 525
               S  K  L   +++         G    D Q +  D V+LS LT A  P    TP  
Sbjct: 193 LHSYSTQKGPLKAGEQRAGSEVISRGGPRKADGQRQALDYVELSPLTQA-SPQRARTPAR 251

Query: 526 DDPNERESDRVYLDLTPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEP 585
                 + + +  DL           + +++         D+ T  +PA  GP      P
Sbjct: 252 TPDRLAKQEELERDL-----------AQRSEERRKWFEATDSRTPEVPAGEGPRRGLGAP 300

Query: 586 CIKCPEN-LGE------QQLESLE-PEDPSLRITTVKIQTEQQRISFPPSCPDAVVATP- 636
             +  +N L E      Q+LE L   E+  + +T +  Q+  +R   P    +A+     
Sbjct: 301 LTEDQQNRLSEEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHEALEKEVQ 360

Query: 637 -----------PGASPPVKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGH 685
                       G +P    R +     I  G    EA  +   E +   ++  EE++ H
Sbjct: 361 ALRAQLEAWRLQGEAPQSALRSQ-EDGHIPPGYISQEACERSLAEMESSHQQVMEELQRH 419

Query: 686 LAQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLK 745
             +  +  ++ KE LL        +++E   K   EE     SR +    S+ +  D L+
Sbjct: 420 HERELQRLQQEKEWLLAEETAATASAIEAMKKAYQEEL----SRELSKTRSLQQGPDGLR 475

Query: 746 KAEAGPV 752
           K     V
Sbjct: 476 KQHQSDV 482


>gi|88501741 TRIO and F-actin binding protein isoform 2 [Homo
           sapiens]
          Length = 431

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 55/254 (21%), Positives = 94/254 (37%), Gaps = 21/254 (8%)

Query: 348 EPVERSLETSSYLNVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQ--QPLSLVGCEVVP 405
           EP   SL T+S       SQWK  W  + D+ L +Y+D    +  +    + L  C  V 
Sbjct: 80  EPPSPSLTTTS------TSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVT 133

Query: 406 DPSPDHLYSFRILHKGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRV 465
           + +    Y F+I H  + +  L A +S    +W+  L       + P+       + +  
Sbjct: 134 EYAVQRNYGFQI-HTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKENA 192

Query: 466 SCIVSAAKNSLLLMQRKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVA 525
               S  K  L   +++         G    D Q +  D V+LS LT A  P    TP  
Sbjct: 193 LHSYSTQKGPLKAGEQRAGSEVISRGGPRKADGQRQALDYVELSPLTQA-SPQRARTPAR 251

Query: 526 DDPNERESDRVYLDLTPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEP 585
                 + + +  DL           + +++         D+ T  +PA  GP      P
Sbjct: 252 TPDRLAKQEELERDL-----------AQRSEERRKWFEATDSRTPEVPAGEGPRRGLGAP 300

Query: 586 CIKCPENLGEQQLE 599
             +  +N   +++E
Sbjct: 301 LTEDQQNRLSEEIE 314


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 32/116 (27%), Positives = 61/116 (52%), Gaps = 19/116 (16%)

Query: 645  DRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCT 704
            D L +T A+++  K+ TE +VK  TEE   L++        +A+L +EK+ L+E   +  
Sbjct: 956  DDLELTLAKVEKEKHATENKVKNLTEELSGLDET-------IAKLTREKKALQEAHQQAL 1008

Query: 705  D------------KEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAE 748
            D             +  + LEQ++++++     E+  RVDLE +  +++ +LK A+
Sbjct: 1009 DDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQ 1064



 Score = 33.5 bits (75), Expect = 0.82
 Identities = 23/101 (22%), Positives = 50/101 (49%), Gaps = 6/101 (5%)

Query: 651  SAEIKLGKNRTEA-----EVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTD 705
            +AE K  K  T+A     E+K+  +    LE+ K+ +   +  L+    E ++  LK   
Sbjct: 1751 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1810

Query: 706  KEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
            K++   LE +++E++ E  GE+ +  +    + + +  +K+
Sbjct: 1811 KQI-QKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKE 1850



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 687 AQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
           A+  KE   +KE   K  D+  LA  E K KE++E+       + DL+L +    +NL  
Sbjct: 844 AETEKEMATMKEEFQKTKDE--LAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLD 901

Query: 747 AE 748
           AE
Sbjct: 902 AE 903



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 34/155 (21%), Positives = 63/155 (40%), Gaps = 6/155 (3%)

Query: 595  EQQLESLEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEI 654
            E+Q+E++  +  SL  T  ++Q E + +       +++ A            L     + 
Sbjct: 1402 EEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKC 1461

Query: 655  KLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQ 714
            +  +   EA +K        L K K      L QL   KRE K        ++ +A L +
Sbjct: 1462 EESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNL------EQEIADLTE 1515

Query: 715  KLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEA 749
            ++ E  +     E  R  +EL   +++  L++AEA
Sbjct: 1516 QIAENGKTIHELEKSRKQIELEKADIQLALEEAEA 1550


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 73/342 (21%), Positives = 141/342 (41%), Gaps = 65/342 (19%)

Query: 422  EELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSLLLMQR 481
            EELA+ EA+  E     + LL  ++  +   +  T + +DA+   C       S +L++ 
Sbjct: 865  EELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEE-RC--EGLIKSKILLEA 921

Query: 482  KFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVADDPNERESDRVYLDLT 541
            K  E    +      + +EE+      SEL A     E+         +R+ D + L LT
Sbjct: 922  KVKELTERL------EEEEEMN-----SELVAKKRNLEDKC----SSLKRDIDDLELTLT 966

Query: 542  PVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLESL 601
             V+   H   + + +  S  ++ L+     L  +            K  +   +Q L+ L
Sbjct: 967  KVEKEKHATEN-KVKNLSEEMTALEENISKLTKEK-----------KSLQEAHQQTLDDL 1014

Query: 602  EPEDPSLR-ITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNR 660
            + E+  +  +  +  + EQQ      S                + +LR   A+++  K +
Sbjct: 1015 QVEEDKVNGLIKINAKLEQQTDDLEGSLEQ-------------EKKLR---ADLERAKRK 1058

Query: 661  TEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEV--------LASL 712
             E ++K   E    LE  K++I     +L+K++ EL +   K  D++V        +  L
Sbjct: 1059 LEGDLKMSQESIMDLENDKQQIE---EKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKEL 1115

Query: 713  EQKLKEIDEECRGE-------ESRRVDLELSIMEVKDNLKKA 747
            + +++E++EE   E       E +R DL   + E+ + L++A
Sbjct: 1116 QARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEA 1157



 Score = 37.4 bits (85), Expect = 0.057
 Identities = 38/160 (23%), Positives = 69/160 (43%), Gaps = 40/160 (25%)

Query: 645  DRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCT 704
            D L +T  +++  K+ TE +VK  +EE   LE+       ++++L KEK+ L+E   +  
Sbjct: 959  DDLELTLTKVEKEKHATENKVKNLSEEMTALEE-------NISKLTKEKKSLQEAHQQTL 1011

Query: 705  DK------------EVLASLEQKLKEIDEECRGEESRRVDLEL--------------SIM 738
            D             ++ A LEQ+  +++     E+  R DLE               SIM
Sbjct: 1012 DDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIM 1071

Query: 739  E-------VKDNLKKAEAGPVTLGTTVDTTHLENVSPRPK 771
            +       +++ LKK E     L   +D   + ++  + K
Sbjct: 1072 DLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKK 1111



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 25/122 (20%), Positives = 54/122 (44%), Gaps = 23/122 (18%)

Query: 644  KDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKC 703
            K +L  + AE++  +     E +  + E  ++    EE+   L  LR+E + L+E +   
Sbjct: 1461 KQKLDESQAELEAAQK----ESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDL 1516

Query: 704  TDK-------------------EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNL 744
            T++                   +  + L+  L+E++     EES+ + ++L + +VK  L
Sbjct: 1517 TEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSEL 1576

Query: 745  KK 746
             +
Sbjct: 1577 DR 1578



 Score = 31.2 bits (69), Expect = 4.1
 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 687 AQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
           A+  KE   +KE   +   KE LA  E + KE++E+       + DL+L +    +NL  
Sbjct: 847 AEAEKEMATMKEDFERT--KEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMD 904

Query: 747 AE 748
           AE
Sbjct: 905 AE 906



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 22/84 (26%), Positives = 42/84 (50%), Gaps = 6/84 (7%)

Query: 651  SAEIKLGKNRTEA-----EVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTD 705
            +AE K  K  T+A     E+K+  +    LE+ K+ +   +  L+    E ++  LK   
Sbjct: 1754 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1813

Query: 706  KEVLASLEQKLKEIDEECRGEESR 729
            K++   LE +++E++ E   E+ R
Sbjct: 1814 KQI-QKLENRVRELENELDVEQKR 1836


>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 523

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 27/106 (25%), Positives = 57/106 (53%), Gaps = 1/106 (0%)

Query: 644 KDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLK- 702
           ++RLR     ++  + R   + +R  E++ERL +++E +R    +L +++  L+E   + 
Sbjct: 198 EERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERL 257

Query: 703 CTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAE 748
           C  +E L   E++L+E +E    +E R  + E  + E ++ L + E
Sbjct: 258 CEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQE 303



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 37/160 (23%), Positives = 74/160 (46%), Gaps = 19/160 (11%)

Query: 593 LGEQQLESLEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSA 652
           L  +Q E L  ++  LR    +++ +++R+     C               ++RLR    
Sbjct: 193 LNRRQEERLREQEERLREQEERLREQEERL-----CEQ-------------EERLREQEE 234

Query: 653 EIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLK-CTDKEVLAS 711
            ++  + R   + +R  E +ERL +++E +     +LR+++  L E   + C  +E L  
Sbjct: 235 RLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLRE 294

Query: 712 LEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEAGP 751
            E++L E +E  R +E R  + E  + E ++ L + E  P
Sbjct: 295 QEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLP 334



 Score = 38.5 bits (88), Expect = 0.025
 Identities = 26/108 (24%), Positives = 59/108 (54%), Gaps = 5/108 (4%)

Query: 644 KDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKC 703
           ++RLR     +   + R   + +R  E++ERL +++E +R    +L +++  L+E   + 
Sbjct: 268 EERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERL 327

Query: 704 TDKEVLASLEQKLKEID-----EECRGEESRRVDLELSIMEVKDNLKK 746
            ++E L   E+ L+E++     E  + E+ R ++ E  + EV++ L++
Sbjct: 328 CEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQ 375


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 33/116 (28%), Positives = 60/116 (51%), Gaps = 19/116 (16%)

Query: 645  DRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCT 704
            D L +T A+++  K+ TE +VK  TEE   L++        +A+L KEK+ L+ET  +  
Sbjct: 958  DDLELTLAKVEKEKHATENKVKNLTEEMAGLDET-------IAKLSKEKKALQETHQQTL 1010

Query: 705  DK------------EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAE 748
            D             +    LEQ++ +++     E+  R+DLE +  +++ +LK A+
Sbjct: 1011 DDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1066



 Score = 38.1 bits (87), Expect = 0.033
 Identities = 74/330 (22%), Positives = 133/330 (40%), Gaps = 41/330 (12%)

Query: 422  EELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSLLLMQR 481
            +ELAK EAK  E     + LL  ++  +   +       DA+   C     KN + L + 
Sbjct: 864  DELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEE-RC-EQLIKNKIQL-EA 920

Query: 482  KFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVADDPNERESDRVYLDLT 541
            K  E           +R EE  ++   +ELTA     E+         +++ D + L L 
Sbjct: 921  KIKEVT---------ERAEE--EEEINAELTAKKRKLEDECSEL----KKDIDDLELTLA 965

Query: 542  PVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLESL 601
             V+   H   + + +  +  ++ LD     L  +            K  +   +Q L+ L
Sbjct: 966  KVEKEKHATEN-KVKNLTEEMAGLDETIAKLSKEK-----------KALQETHQQTLDDL 1013

Query: 602  EPEDPSLRITT-VKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNR 660
            + E+  + I T  K + EQQ      S     +         ++   R    ++KL +  
Sbjct: 1014 QAEEDKVNILTKAKTKLEQQVDDLEGS-----LEQEKKLRMDLERAKRKLEGDLKLAQES 1068

Query: 661  TEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEID 720
            T        +  E+LEKK+ EI   ++++  E  +  E  L+   KE+ A +E+  +EI+
Sbjct: 1069 TMDMENDKQQLDEKLEKKEFEISNLISKI--EDEQAVEIQLQKKIKELQARIEELGEEIE 1126

Query: 721  EECRGE---ESRRVDLELSIMEVKDNLKKA 747
             E       E +R DL   + E+ + L++A
Sbjct: 1127 AERASRAKAEKQRSDLSRELEEISERLEEA 1156



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 687 AQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
           A+  KE   +KE   K  D+  LA  E K KE++E+       + DL+L +    D+L  
Sbjct: 846 AETEKEMATMKEEFQKTKDE--LAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903

Query: 747 AE 748
           AE
Sbjct: 904 AE 905



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 22/87 (25%), Positives = 43/87 (49%), Gaps = 6/87 (6%)

Query: 651  SAEIKLGKNRTEA-----EVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTD 705
            +AE K  K  T+A     E+K+  +    LE+ K+ +   +  L+    E ++  LK   
Sbjct: 1753 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1812

Query: 706  KEVLASLEQKLKEIDEECRGEESRRVD 732
            K++   LE +++E++ E   E+ R  +
Sbjct: 1813 KQI-QKLEARVRELEGEVENEQKRNAE 1838


>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
           sapiens]
          Length = 956

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 51/190 (26%), Positives = 79/190 (41%), Gaps = 33/190 (17%)

Query: 598 LESLEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPP-GASPPV------------- 643
           LES   ED  L  +++   +       PP+ P    +T P   S P+             
Sbjct: 272 LESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGSTE 331

Query: 644 KDRLRVTSAEIKLGKN---RTEAEVK----------------RYTEEKERLEKKKEEIRG 684
           K++LR+   + +LGK    R E E K                +  EEKE  EK++ E R 
Sbjct: 332 KNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKRE 391

Query: 685 HLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNL 744
              + + EK+ LKE   K   + + A LE+K K+ +E+   EE +R+  E + +      
Sbjct: 392 KDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQK 451

Query: 745 KKAEAGPVTL 754
            K    P TL
Sbjct: 452 PKTPQAPKTL 461


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 32/116 (27%), Positives = 59/116 (50%), Gaps = 19/116 (16%)

Query: 645  DRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCT 704
            D L +T A+++  K+ TE +VK  TEE   L++        +A+L KEK+ L+E   +  
Sbjct: 961  DDLELTLAKVEKEKHATENKVKNLTEEMAGLDET-------IAKLTKEKKALQEAHQQTL 1013

Query: 705  DK------------EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAE 748
            D             +    LEQ++ +++     E+  R+DLE +  +++ +LK A+
Sbjct: 1014 DDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1069



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 57/258 (22%), Positives = 99/258 (38%), Gaps = 50/258 (19%)

Query: 507  DLSELTAAVEPTEEATPVADDPNERESDRVYLDLTPVKSFLHGPSSAQAQASSPTLSCLD 566
            ++ EL A +E TE +  +A+      S+RV L  T   S ++     +   S       D
Sbjct: 1690 EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMED 1749

Query: 567  NATEALPADSGPGPTPDEPCIKCPENLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPP 626
               EA  A+        E   K   +      E  + +D S  +  +K   EQ       
Sbjct: 1750 ILQEARNAE--------EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT------ 1795

Query: 627  SCPDAVVATPPGASPPVKD-RLRVTSAE---IKLGKN---RTEAEVKRYTEEKERLEKKK 679
                            VKD +LR+  AE   +K GK    + EA V+    E E  +K+ 
Sbjct: 1796 ----------------VKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRN 1839

Query: 680  EE-IRGHLAQLRKEKRELKETLLKCTD--------KEVLASLEQKLKEIDEECRGEESRR 730
             E ++G    LRK +R +KE   +  +        ++++  L+ K+K    +    E + 
Sbjct: 1840 AEAVKG----LRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQS 1895

Query: 731  VDLELSIMEVKDNLKKAE 748
                    +++  L++AE
Sbjct: 1896 NTNLAKFRKLQHELEEAE 1913



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 22/116 (18%), Positives = 53/116 (45%), Gaps = 9/116 (7%)

Query: 643  VKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETL-- 700
            VK +L    +E+K+  +   + V+  ++ K  LEK    +   L++L+ ++ E +  +  
Sbjct: 1219 VKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIND 1278

Query: 701  -------LKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEA 749
                   L+    E    L++K   + +  RG+++    +E    ++++ +K   A
Sbjct: 1279 LTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNA 1334



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 2/62 (3%)

Query: 687 AQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
           A+  KE   +KE   K  D+  LA  E K KE++E+       + DL+L +    + L  
Sbjct: 849 AETEKEMATMKEEFQKIKDE--LAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906

Query: 747 AE 748
           AE
Sbjct: 907 AE 908



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 31/113 (27%), Positives = 55/113 (48%), Gaps = 20/113 (17%)

Query: 643 VKDRLRVTSAEIKLGKNRTEAEVKRYT--EEKERLEKKKEEIRGHLA-------QLRKEK 693
           +KD L  + A+      R E E K  T  +EK  L+ + +     LA       QL K K
Sbjct: 865 IKDELAKSEAK------RKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTK 918

Query: 694 RELKETLLKCTDK-----EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVK 741
            +L+  + + T++     E+ A L  K +++++EC   +    DLEL++ +V+
Sbjct: 919 IQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 32/116 (27%), Positives = 59/116 (50%), Gaps = 19/116 (16%)

Query: 645  DRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCT 704
            D L +T A+++  K+ TE +VK  TEE   L++        +A+L KEK+ L+E   +  
Sbjct: 961  DDLELTLAKVEKEKHATENKVKNLTEEMAGLDET-------IAKLTKEKKALQEAHQQTL 1013

Query: 705  DK------------EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAE 748
            D             +    LEQ++ +++     E+  R+DLE +  +++ +LK A+
Sbjct: 1014 DDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1069



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 57/258 (22%), Positives = 99/258 (38%), Gaps = 50/258 (19%)

Query: 507  DLSELTAAVEPTEEATPVADDPNERESDRVYLDLTPVKSFLHGPSSAQAQASSPTLSCLD 566
            ++ EL A +E TE +  +A+      S+RV L  T   S ++     +   S       D
Sbjct: 1690 EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMED 1749

Query: 567  NATEALPADSGPGPTPDEPCIKCPENLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPP 626
               EA  A+        E   K   +      E  + +D S  +  +K   EQ       
Sbjct: 1750 ILQEARNAE--------EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT------ 1795

Query: 627  SCPDAVVATPPGASPPVKD-RLRVTSAE---IKLGKN---RTEAEVKRYTEEKERLEKKK 679
                            VKD +LR+  AE   +K GK    + EA V+    E E  +K+ 
Sbjct: 1796 ----------------VKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRN 1839

Query: 680  EE-IRGHLAQLRKEKRELKETLLKCTD--------KEVLASLEQKLKEIDEECRGEESRR 730
             E ++G    LRK +R +KE   +  +        ++++  L+ K+K    +    E + 
Sbjct: 1840 AEAVKG----LRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQS 1895

Query: 731  VDLELSIMEVKDNLKKAE 748
                    +++  L++AE
Sbjct: 1896 NTNLAKFRKLQHELEEAE 1913



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 22/116 (18%), Positives = 53/116 (45%), Gaps = 9/116 (7%)

Query: 643  VKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETL-- 700
            VK +L    +E+K+  +   + V+  ++ K  LEK    +   L++L+ ++ E +  +  
Sbjct: 1219 VKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIND 1278

Query: 701  -------LKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEA 749
                   L+    E    L++K   + +  RG+++    +E    ++++ +K   A
Sbjct: 1279 LTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNA 1334



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 2/62 (3%)

Query: 687 AQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
           A+  KE   +KE   K  D+  LA  E K KE++E+       + DL+L +    + L  
Sbjct: 849 AETEKEMATMKEEFQKIKDE--LAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906

Query: 747 AE 748
           AE
Sbjct: 907 AE 908



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 31/113 (27%), Positives = 55/113 (48%), Gaps = 20/113 (17%)

Query: 643 VKDRLRVTSAEIKLGKNRTEAEVKRYT--EEKERLEKKKEEIRGHLA-------QLRKEK 693
           +KD L  + A+      R E E K  T  +EK  L+ + +     LA       QL K K
Sbjct: 865 IKDELAKSEAK------RKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTK 918

Query: 694 RELKETLLKCTDK-----EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVK 741
            +L+  + + T++     E+ A L  K +++++EC   +    DLEL++ +V+
Sbjct: 919 IQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971


>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
           sapiens]
          Length = 638

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 41/189 (21%), Positives = 82/189 (43%), Gaps = 17/189 (8%)

Query: 592 NLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTS 651
           N   +  E+L  E  +L+   +  Q E++++       D+++      S  +  +L    
Sbjct: 219 NRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQ 278

Query: 652 AEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLAS 711
            E+   KN  E E+K+  +E ++L++K+E+    + QL +E +         +  E L  
Sbjct: 279 EEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAK---------SRAEELKL 329

Query: 712 LEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKA--------EAGPVTLGTTVDTTHL 763
           LE+KLK  + E     +      L + E  D++ ++        E+      + ++   L
Sbjct: 330 LEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKL 389

Query: 764 ENVSPRPKA 772
           EN S + KA
Sbjct: 390 ENSSLQEKA 398


>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
           sapiens]
          Length = 725

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 41/189 (21%), Positives = 82/189 (43%), Gaps = 17/189 (8%)

Query: 592 NLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTS 651
           N   +  E+L  E  +L+   +  Q E++++       D+++      S  +  +L    
Sbjct: 306 NRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQ 365

Query: 652 AEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLAS 711
            E+   KN  E E+K+  +E ++L++K+E+    + QL +E +         +  E L  
Sbjct: 366 EEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAK---------SRAEELKL 416

Query: 712 LEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKA--------EAGPVTLGTTVDTTHL 763
           LE+KLK  + E     +      L + E  D++ ++        E+      + ++   L
Sbjct: 417 LEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKL 476

Query: 764 ENVSPRPKA 772
           EN S + KA
Sbjct: 477 ENSSLQEKA 485


>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
           sapiens]
          Length = 709

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 41/189 (21%), Positives = 82/189 (43%), Gaps = 17/189 (8%)

Query: 592 NLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTS 651
           N   +  E+L  E  +L+   +  Q E++++       D+++      S  +  +L    
Sbjct: 290 NRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQ 349

Query: 652 AEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLAS 711
            E+   KN  E E+K+  +E ++L++K+E+    + QL +E +         +  E L  
Sbjct: 350 EEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAK---------SRAEELKL 400

Query: 712 LEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKA--------EAGPVTLGTTVDTTHL 763
           LE+KLK  + E     +      L + E  D++ ++        E+      + ++   L
Sbjct: 401 LEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKL 460

Query: 764 ENVSPRPKA 772
           EN S + KA
Sbjct: 461 ENSSLQEKA 469


>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
           sapiens]
          Length = 724

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 41/189 (21%), Positives = 82/189 (43%), Gaps = 17/189 (8%)

Query: 592 NLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTS 651
           N   +  E+L  E  +L+   +  Q E++++       D+++      S  +  +L    
Sbjct: 305 NRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQ 364

Query: 652 AEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLAS 711
            E+   KN  E E+K+  +E ++L++K+E+    + QL +E +         +  E L  
Sbjct: 365 EEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAK---------SRAEELKL 415

Query: 712 LEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKA--------EAGPVTLGTTVDTTHL 763
           LE+KLK  + E     +      L + E  D++ ++        E+      + ++   L
Sbjct: 416 LEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKL 475

Query: 764 ENVSPRPKA 772
           EN S + KA
Sbjct: 476 ENSSLQEKA 484


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 32/116 (27%), Positives = 59/116 (50%), Gaps = 19/116 (16%)

Query: 645  DRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCT 704
            D L +T A+++  K+ TE +VK  TEE   L++        +A+L KEK+ L+E   +  
Sbjct: 959  DDLELTLAKVEKEKHATENKVKNLTEEMAGLDET-------IAKLTKEKKALQEAHQQTL 1011

Query: 705  DK------------EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAE 748
            D             +    LEQ++ +++     E+  R+DLE +  +++ +LK A+
Sbjct: 1012 DDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQ 1067



 Score = 33.5 bits (75), Expect = 0.82
 Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 687 AQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
           A+  KE   +KE   K   KE LA  E K KE++E+       + DL+L +    D+L  
Sbjct: 847 AETEKEMANMKEEFEKT--KEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLAD 904

Query: 747 AE 748
           AE
Sbjct: 905 AE 906



 Score = 33.5 bits (75), Expect = 0.82
 Identities = 23/87 (26%), Positives = 44/87 (50%), Gaps = 6/87 (6%)

Query: 651  SAEIKLGKNRTEA-----EVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTD 705
            +AE K  K  T+A     E+K+  +    LE+ K+ +   +  L+    E ++  LK   
Sbjct: 1754 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1813

Query: 706  KEVLASLEQKLKEIDEECRGEESRRVD 732
            K++   LE +++E++ E   E+ R V+
Sbjct: 1814 KQI-QKLEARVRELEGEVESEQKRNVE 1839



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 31/114 (27%), Positives = 55/114 (48%), Gaps = 15/114 (13%)

Query: 643 VKDRLRVTSAEI-KLGKNRTEAEVKRYT--EEKERLEKKKEEIRGHLA-------QLRKE 692
           +K+    T  E+ K    R E E K  T  +EK  L+ + +     LA       QL K 
Sbjct: 856 MKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKT 915

Query: 693 KRELKETLLKCTDK-----EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVK 741
           K +L+  + + T++     E+ A L  K +++++EC   +    DLEL++ +V+
Sbjct: 916 KIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 969



 Score = 31.2 bits (69), Expect = 4.1
 Identities = 59/259 (22%), Positives = 101/259 (38%), Gaps = 52/259 (20%)

Query: 507  DLSELTAAVEPTEEATPVADDPNERESDRVYLDLTPVKSFLHGPSSAQAQASSPTLSCLD 566
            ++ EL A +E TE +  +A+      S+RV L  T   S ++     +   S       D
Sbjct: 1688 EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMED 1747

Query: 567  NATEALPADSGPGPTPDEPCIKCPENLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPP 626
               EA  A+        E   K   +      E  + +D S  +  +K   EQ       
Sbjct: 1748 IIQEARNAE--------EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT------ 1793

Query: 627  SCPDAVVATPPGASPPVKD-RLRVTSAE---IKLGKN---RTEAEVKRYTEEKERLEKKK 679
                            VKD + R+  AE   +K GK    + EA V+    E E  +K+ 
Sbjct: 1794 ----------------VKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRN 1837

Query: 680  -EEIRGHLAQLRKEKRELKETLLKCTD--------KEVLASLEQKLKEIDEEC-RGEESR 729
             E ++G    LRK +R++KE   +  +        ++++  L+ K+K    +    EE  
Sbjct: 1838 VEAVKG----LRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQS 1893

Query: 730  RVDLELSIMEVKDNLKKAE 748
             V+L      ++  L++AE
Sbjct: 1894 NVNLS-KFRRIQHELEEAE 1911


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 35/108 (32%), Positives = 56/108 (51%), Gaps = 6/108 (5%)

Query: 643 VKDRLRVTSAEIKLGKNRTEAEVKRYTEEKER---LEKKKEEIRGHLAQLRKEKRELKET 699
           ++ RL+    E    + R E  +KR   E+ER   L K +E+      QLR+E++E +E 
Sbjct: 598 LEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQ 657

Query: 700 LLKCTDKEVLASLEQKLK-EIDEECRGEESRRVDLELSIMEVKDNLKK 746
            LK  ++E    LEQ+LK E +EE R +E    + E +   +K  + K
Sbjct: 658 RLKREEEE--ERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPK 703



 Score = 37.7 bits (86), Expect = 0.043
 Identities = 30/93 (32%), Positives = 52/93 (55%), Gaps = 9/93 (9%)

Query: 647 LRVTSAEIKLGKNRTEAEVKRYTEEK--ERLEKKKEEIRGHLA-----QLRKEKRELKET 699
           L++   E +  + R E +++R  EE+  +RL++++EE R         QLR+E+ E +E 
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ 548

Query: 700 LLKCTDKEVLAS--LEQKLKEIDEECRGEESRR 730
           LLK  +++ L     EQ+LK   EE R +  +R
Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKR 581



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 7/76 (9%)

Query: 662  EAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDE 721
            E   KR  +E ER  +KK+E++    QL +E+RE +    +  ++E     E++L++ +E
Sbjct: 1006 EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKR----RLQERERQYREEEELQQEEE 1061

Query: 722  ECRGEE---SRRVDLE 734
            +  GEE    RR +LE
Sbjct: 1062 QLLGEERETRRRQELE 1077



 Score = 35.4 bits (80), Expect = 0.22
 Identities = 29/91 (31%), Positives = 49/91 (53%), Gaps = 4/91 (4%)

Query: 644 KDRLRVTSAEIKLGKNRTEAEVKRYTEE-KERLEKKKEEIRGHLAQLRKEKRELKETLLK 702
           +++L     E +L + R E  +KR  EE +++L K++EE R    +L++E+ E  E  LK
Sbjct: 546 REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQ--RLKREQEERLEQRLK 603

Query: 703 CTDKEVLASLEQKLKEIDEECRGEESRRVDL 733
             + E L   E++ + +  E   EE RR  L
Sbjct: 604 REEVERLEQEERREQRLKRE-EPEEERRQQL 633



 Score = 34.3 bits (77), Expect = 0.48
 Identities = 23/94 (24%), Positives = 52/94 (55%), Gaps = 6/94 (6%)

Query: 639 ASPPVKDRLRVTSAEIKLGKNRTEAEV--KRYTEEKERLEKKKEEIRGHLAQLRKEKREL 696
           A P ++++LR     ++  +   + E   KR  +E+ER  +++E+++    QL +E+RE 
Sbjct: 891 AKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREK 950

Query: 697 KETLLKCTDKEVLASLEQKLKEIDEECRGEESRR 730
           +    +  ++E     ++KL++ +E+  GEE  +
Sbjct: 951 R----RRQERERQYRKDKKLQQKEEQLLGEEPEK 980



 Score = 34.3 bits (77), Expect = 0.48
 Identities = 26/83 (31%), Positives = 44/83 (53%), Gaps = 4/83 (4%)

Query: 670  EEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLAS--LEQKLK--EIDEECRG 725
            +E +R ++K +E +  L + R+EKR  +ET  K  ++E L     EQ L+  E D + R 
Sbjct: 1305 KEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE 1364

Query: 726  EESRRVDLELSIMEVKDNLKKAE 748
            EE R  +     +E +  L++ E
Sbjct: 1365 EELRHQEQGRKFLEEEQRLRRQE 1387



 Score = 33.9 bits (76), Expect = 0.63
 Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 10/100 (10%)

Query: 653 EIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRK------EKRELKETLLKCTDK 706
           E K  + R E  +KR  EE+    K++EE   H  + RK      ++ E +E  LK  ++
Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEE 494

Query: 707 EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
           E     E++    +++ R E+  R +  L   E ++ L++
Sbjct: 495 ERREQQERR----EQQLRREQEERREQRLKRQEEEERLQQ 530



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 24/85 (28%), Positives = 44/85 (51%), Gaps = 11/85 (12%)

Query: 660 RTEAEVKRYTEE---------KERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLA 710
           R E +++R  EE         +E+ E+++++      QLR+E+ E +E  L+   +E   
Sbjct: 301 RREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE--E 358

Query: 711 SLEQKLKEIDEECRGEESRRVDLEL 735
             EQ+L+   EE R E+  R + +L
Sbjct: 359 RREQQLRREQEEERREQQLRREQQL 383



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 23/93 (24%), Positives = 48/93 (51%), Gaps = 1/93 (1%)

Query: 654 IKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLE 713
           +K  + R +  +KR  EE+     K+EE+     + R+E+R  +E   +   +++L S E
Sbjct: 579 LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEE 638

Query: 714 QKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
           Q+ +   ++ R E+  R +  L   E ++ L++
Sbjct: 639 QEERR-QQQLRREQQERREQRLKREEEEERLEQ 670



 Score = 31.2 bits (69), Expect = 4.1
 Identities = 22/96 (22%), Positives = 52/96 (54%), Gaps = 5/96 (5%)

Query: 658  KNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRK---EKRELKETLLKCTDKEVLASLEQ 714
            K R +   K+Y EE+E  +++++ +R    + R+   E++  K+  L+  ++++L    +
Sbjct: 980  KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREERE 1039

Query: 715  K--LKEIDEECRGEESRRVDLELSIMEVKDNLKKAE 748
            K  L+E + + R EE  + + E  + E ++  ++ E
Sbjct: 1040 KRRLQERERQYREEEELQQEEEQLLGEERETRRRQE 1075



 Score = 30.8 bits (68), Expect = 5.3
 Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 4/73 (5%)

Query: 662  EAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKE----TLLKCTDKEVLASLEQKLK 717
            E   KR  +E+ER  +++EE++    QL +E+RE +           ++EV    EQ L+
Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155

Query: 718  EIDEECRGEESRR 730
            E  E+ R +E  R
Sbjct: 1156 EEPEKRRRQELER 1168



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 24/80 (30%), Positives = 44/80 (55%), Gaps = 4/80 (5%)

Query: 660 RTEAEVKRYTEE--KERLEKKKEEIRGH--LAQLRKEKRELKETLLKCTDKEVLASLEQK 715
           + E E +R+ +E  K++L++ +EE R    L    +E+RE +E   +   +E     EQ+
Sbjct: 459 KREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQR 518

Query: 716 LKEIDEECRGEESRRVDLEL 735
           LK  +EE R ++  R + +L
Sbjct: 519 LKRQEEEERLQQRLRSEQQL 538


>gi|11119430 testis-specific kinase substrate [Homo sapiens]
          Length = 592

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 43/173 (24%), Positives = 76/173 (43%), Gaps = 27/173 (15%)

Query: 592 NLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPPSCP---------DAVVATPPGASPP 642
           N+    L ++EP D +   +TV+  + Q  ++ PP+ P         D         S  
Sbjct: 81  NVSLLNLAAMEPTDSTGTDSTVEDLSGQLTLAGPPASPTLPWDPDDADITEILSGVNSGL 140

Query: 643 VKDRLRVTSAEIKLGK-----NRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRK------ 691
           V+ +  +TS + K  +        ++E    +E  ER  ++ EE+ G+  QL++      
Sbjct: 141 VRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVT 200

Query: 692 ---EKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVK 741
              E  E+K  +LK       A LE+KL+ + ++ + E  RR + EL   E K
Sbjct: 201 RSVEDAEIKTNVLKQNS----ALLEEKLRYLQQQLQDETPRRQEAELQEPEEK 249


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 32/139 (23%), Positives = 63/139 (45%), Gaps = 11/139 (7%)

Query: 654  IKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDK------E 707
            +K  +++ EA  K++ EEK+ LE+K  ++   +     + +ELK    + T +      E
Sbjct: 938  VKAEQSQQEA-AKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEE 996

Query: 708  VLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLENVS 767
            +L +L++ L + +++ +G       L   + E++    KA+A      T  D   +    
Sbjct: 997  ILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQ----TAEDAMQIMEQM 1052

Query: 768  PRPKAVTPASAPDCTPVNS 786
             + K  T AS  D    N+
Sbjct: 1053 TKEKTETLASLEDTKQTNA 1071


>gi|4506751 restin isoform a [Homo sapiens]
          Length = 1427

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 32/139 (23%), Positives = 63/139 (45%), Gaps = 11/139 (7%)

Query: 654  IKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDK------E 707
            +K  +++ EA  K++ EEK+ LE+K  ++   +     + +ELK    + T +      E
Sbjct: 973  VKAEQSQQEA-AKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEE 1031

Query: 708  VLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLENVS 767
            +L +L++ L + +++ +G       L   + E++    KA+A      T  D   +    
Sbjct: 1032 ILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQ----TAEDAMQIMEQM 1087

Query: 768  PRPKAVTPASAPDCTPVNS 786
             + K  T AS  D    N+
Sbjct: 1088 TKEKTETLASLEDTKQTNA 1106


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 41/172 (23%), Positives = 70/172 (40%), Gaps = 21/172 (12%)

Query: 550 PSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLESLEPEDPSLR 609
           P +  A  ++ +   L    E+     GP P P +      E     + +S  P  P++ 
Sbjct: 49  PDTPPAMKNATSSKQLPLEPESPSGQVGPRPAPPQ------EESPSSEAKSRGPTPPAMG 102

Query: 610 ITTVKIQTEQQRISFPP--SCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNRTEAEVKR 667
                      R + PP  S   +  A P   SPP K  ++      KL K R E   K 
Sbjct: 103 ----------PRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERAKY 152

Query: 668 YTEEKERLEKKKEEIRG-HLAQLRKEKRELKETLLKCTDKEVLASLEQKLKE 718
              +K    +K+E+ +     QL++ +R L+E  LK   +   A+LE++ ++
Sbjct: 153 LAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQRR--AALEERQRQ 202



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 53/203 (26%), Positives = 76/203 (37%), Gaps = 21/203 (10%)

Query: 550 PSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLESLEPEDPSLR 609
           P S +   +SP    +    EA  + S  GP       +   N  E    +     P+  
Sbjct: 494 PPSPRGTTASPK-GRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPS 552

Query: 610 ITTVKIQTEQQRISFPPSCPDAVVATPPGASPPV---KDRLRVTSAEIK---LGKNRTEA 663
            T    Q EQ     P     AV+ +PP  +PPV   K     T  E     L + R +A
Sbjct: 553 PTPAPPQKEQPPAETPTDA--AVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQA 610

Query: 664 EVKRYTEEKERLEKKKEEIRGHLAQLRKE------------KRELKETLLKCTDKEVLAS 711
             +R  EE+ER  + + + R    QL +E            +RE +E   K   ++    
Sbjct: 611 REQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQE 670

Query: 712 LEQKLKEIDEECRGEESRRVDLE 734
             QK KE  E    EE+ R  LE
Sbjct: 671 RLQKQKEEAEARSREEAERQRLE 693



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 51/238 (21%), Positives = 89/238 (37%), Gaps = 17/238 (7%)

Query: 507 DLSELTAAVEPTEEATPVADDPNERESDRVYLDLTPVKSFLHGPSSAQAQASSPTLSC-L 565
           +  E  +A  P +++       NE+ES       +P  S    P+ A  Q   P      
Sbjct: 513 EAKESPSAAGPEDKSQSKRRASNEKESAA---PASPAPSPAPSPTPAPPQKEQPPAETPT 569

Query: 566 DNATEALPADSGPGPTPDEPCIKCPEN------LGEQQLESLEP-----EDPSLRITTVK 614
           D A    P    P  TP +P     +       L E++ ++ E      ++  L+    K
Sbjct: 570 DAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERDK 629

Query: 615 IQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEI-KLGKNRTEAEVKRYTEEKE 673
              E+Q      +  +             +++ +    E  +L K + EAE  R  EE E
Sbjct: 630 RMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEA-RSREEAE 688

Query: 674 RLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRV 731
           R   ++E+      Q R+E+R+  E ++K T K  ++  +QK    +    G     V
Sbjct: 689 RQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPV 746



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 48/195 (24%), Positives = 74/195 (37%), Gaps = 36/195 (18%)

Query: 635 TPPGASPPVKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKR 694
           T P A+ PV  R    S        R+   V R     ER E++K    G  A +R+   
Sbjct: 352 THPSAAVPVCPRSASASPLTPCSVTRS---VHRCAPAGERGERRKPNAGGSPAPVRRRPE 408

Query: 695 ELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEAGPVTL 754
                          AS  QK ++ D+E   E+      E S +  + +LKK ++ P + 
Sbjct: 409 ---------------ASPVQKKEKKDKERENEK------EKSALARERSLKKRQSLPASP 447

Query: 755 GTTVDTTHLENVSPRPKAVTPAS--------APDCTPVNSATTLKNRPLS---VVVTGKG 803
              +  +    +SP+ KA  P+S        A  C       TL  +P S      + KG
Sbjct: 448 RARLSASTASELSPKSKA-RPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKG 506

Query: 804 TVLQKAKEWEKKGAS 818
            V +K +  E   A+
Sbjct: 507 RVRRKEEAKESPSAA 521


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 31/113 (27%), Positives = 57/113 (50%), Gaps = 19/113 (16%)

Query: 645  DRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCT 704
            D L +T A+++  K+ TE +VK  TEE   L++        +A+L KEK+ L+E   +  
Sbjct: 955  DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEI-------IAKLTKEKKALQEAHQQAL 1007

Query: 705  DK------------EVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLK 745
            D             +    LEQ++ +++     E+  R+DLE +  +++ +LK
Sbjct: 1008 DDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 687 AQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKK 746
           A+  KE   +KE   +   KE L   E + KE++E+       + DL+L +   +DNL  
Sbjct: 843 AEREKEMASMKEEFTRL--KEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLAD 900

Query: 747 AE 748
           AE
Sbjct: 901 AE 902



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 25/92 (27%), Positives = 45/92 (48%), Gaps = 8/92 (8%)

Query: 666  KRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKC-TDKEVLASLEQKLKEIDEECR 724
            ++Y E +  LE  ++E R    +L K K   +E+L    T K    +L++++ ++ E+  
Sbjct: 1458 QKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLG 1517

Query: 725  GE-------ESRRVDLELSIMEVKDNLKKAEA 749
                     E  R  LE   ME++  L++AEA
Sbjct: 1518 SSGKTIHELEKVRKQLEAEKMELQSALEEAEA 1549



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 52/250 (20%), Positives = 91/250 (36%), Gaps = 34/250 (13%)

Query: 507  DLSELTAAVEPTEEATPVADDPNERESDRVYLDLTPVKSFLHGPSSAQAQASSPTLSCLD 566
            +L EL A VE TE +  +A+      S+RV L  +   S ++      A  S       +
Sbjct: 1684 ELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEE 1743

Query: 567  NATEALPADSGPGPTPDEPCIKCPENLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPP 626
               E   A+        E   K   +      E  + +D S  +  +K   EQ       
Sbjct: 1744 AVQECRNAE--------EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH 1795

Query: 627  SCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHL 686
               +A      G     K +L+   A ++  +N  EAE KR            E ++G  
Sbjct: 1796 RLDEAEQIALKGG----KKQLQKLEARVRELENELEAEQKR----------NAESVKG-- 1839

Query: 687  AQLRKEKRELKETLLKCTD--------KEVLASLEQKLKEIDEECRGEESRRVDLELSIM 738
              +RK +R +KE   +  +        ++++  L+ K+K    +    E +         
Sbjct: 1840 --MRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFR 1897

Query: 739  EVKDNLKKAE 748
            +V+  L +AE
Sbjct: 1898 KVQHELDEAE 1907



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 20/84 (23%), Positives = 46/84 (54%), Gaps = 2/84 (2%)

Query: 658 KNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLK 717
           KN  + +V+   +     E++ +++  +  QL  + +E+ E L    ++E+ A L  K +
Sbjct: 884 KNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLED--EEEMNAELTAKKR 941

Query: 718 EIDEECRGEESRRVDLELSIMEVK 741
           ++++EC   +    DLEL++ +V+
Sbjct: 942 KLEDECSELKRDIDDLELTLAKVE 965


>gi|50083279 centrosome protein 4 [Homo sapiens]
          Length = 1140

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 31/109 (28%), Positives = 58/109 (53%), Gaps = 5/109 (4%)

Query: 651 SAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKE-VL 709
           +A+ +LG+   + E+KR   E + LE+   +++  L   +KEK  L + LL  +D E V+
Sbjct: 339 TADKELGE--AKKEIKRKLSEMQDLEETMAKLQLELNLCQKEKERLSDELLVKSDLETVV 396

Query: 710 ASLEQKLKEIDE--ECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGT 756
             LEQ+ + + +  E      R++ LE+  M ++  +K+ +  P  L T
Sbjct: 397 HQLEQEKQRLSKKVESFAVTERQLTLEVERMRLEHGIKRRDRSPSRLDT 445



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)

Query: 672 KERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLK 717
           K  LEK  E +     QL  EK ELK  +L    KE + SLE KLK
Sbjct: 603 KSELEKTIEHLTCVNHQLESEKYELKSKVL--IMKETIESLENKLK 646


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 32/117 (27%), Positives = 57/117 (48%), Gaps = 16/117 (13%)

Query: 639 ASPPVKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKE 698
           +SP + D+L+  + E++   N  E  ++ + +E +    K +E++  L + + E  E ++
Sbjct: 275 SSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEK 334

Query: 699 TLLKCTDKEV------------LASLEQKLKEIDEEC----RGEESRRVDLELSIME 739
            L KC D+ V              +LEQKLK++ E+     +  ES R  LE  I E
Sbjct: 335 VLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKE 391



 Score = 37.0 bits (84), Expect = 0.074
 Identities = 24/96 (25%), Positives = 51/96 (53%)

Query: 653  EIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASL 712
            ++K    R + ++K   +  ++LE++KE ++  L+QL+  + + K   +  T  + L + 
Sbjct: 2783 QLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTE 2842

Query: 713  EQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAE 748
             ++LKE  EE   E    +D   S++   + L+KA+
Sbjct: 2843 IKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAK 2878



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 23/75 (30%), Positives = 41/75 (54%), Gaps = 6/75 (8%)

Query: 674 RLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDL 733
           R  +K +E+ G L +L+KEK++ +  L    D    A  +QK K  +E+  G   +R + 
Sbjct: 15  RALQKIQELEGQLDKLKKEKQQRQFQL----DSLEAALQKQKQKVENEKTEGTNLKRENQ 70

Query: 734 ELSIMEVKDNLKKAE 748
            L  ME+ ++L+K +
Sbjct: 71  RL--MEICESLEKTK 83


>gi|14589862 aspartate beta-hydroxylase isoform d [Homo sapiens]
          Length = 210

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 31/92 (33%), Positives = 53/92 (57%), Gaps = 5/92 (5%)

Query: 656 LGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQK 715
           + K +T+A+VK  T+E+ + EK+K E R   ++  + K+  KE + K  DK++ A  +  
Sbjct: 84  VAKRKTKAKVKELTKEELKKEKEKPESRKE-SKNEERKKGKKEDVRK--DKKI-ADADLS 139

Query: 716 LKEIDEECRGEESRRVDLELSIMEVKDNLKKA 747
            KE  +  +  E  +VDLE S  + K+N KK+
Sbjct: 140 RKESPKGKKDREKEKVDLEKS-AKTKENRKKS 170


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.127    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,212,729
Number of Sequences: 37866
Number of extensions: 1832318
Number of successful extensions: 12072
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 125
Number of HSP's successfully gapped in prelim test: 638
Number of HSP's that attempted gapping in prelim test: 9524
Number of HSP's gapped (non-prelim): 2869
length of query: 818
length of database: 18,247,518
effective HSP length: 111
effective length of query: 707
effective length of database: 14,044,392
effective search space: 9929385144
effective search space used: 9929385144
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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