Guide to the Human Genome
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Search of human proteins with 50659104

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo
sapiens]
         (1283 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo s...  2521   0.0  
gi|50363230 RAB11 family interacting protein 1 isoform 2 [Homo s...  1212   0.0  
gi|50363228 RAB11 family interacting protein 1 isoform 1 [Homo s...  1060   0.0  
gi|24308075 RAB11 family interacting protein 5 (class I) [Homo s...   265   3e-70
gi|7662394 RAB11 family interacting protein 2 (class I) [Homo sa...   253   8e-67
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     64   9e-10
gi|148806908 fibronectin type III domain containing 1 [Homo sapi...    64   1e-09
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   60   1e-08
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    60   1e-08
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    60   1e-08
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             59   2e-08
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2...    58   7e-08
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1...    58   7e-08
gi|91982772 mucin 17 [Homo sapiens]                                    57   9e-08
gi|209862789 microtubule associated monoxygenase, calponin and L...    57   1e-07
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   57   1e-07
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   57   1e-07
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        57   1e-07
gi|150170670 piccolo isoform 2 [Homo sapiens]                          54   7e-07
gi|150378539 piccolo isoform 1 [Homo sapiens]                          54   7e-07
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ...    54   1e-06
gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo...    53   2e-06
gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Hom...    53   2e-06
gi|210032580 SET domain containing 1B [Homo sapiens]                   52   3e-06
gi|31324577 molecule interacting with Rab13 [Homo sapiens]             52   3e-06
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                52   4e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   4e-06
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                52   4e-06
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                52   4e-06
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         52   4e-06

>gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo
            sapiens]
          Length = 1283

 Score = 2521 bits (6534), Expect = 0.0
 Identities = 1283/1283 (100%), Positives = 1283/1283 (100%)

Query: 1    MSLMVSAGRGLGAVWSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERS 60
            MSLMVSAGRGLGAVWSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERS
Sbjct: 1    MSLMVSAGRGLGAVWSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERS 60

Query: 61   LGAPVWREEATFELPSLLSSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQGR 120
            LGAPVWREEATFELPSLLSSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQGR
Sbjct: 61   LGAPVWREEATFELPSLLSSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQGR 120

Query: 121  RKTQWYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGK 180
            RKTQWYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGK
Sbjct: 121  RKTQWYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGK 180

Query: 181  NKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPT 240
            NKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPT
Sbjct: 181  NKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPT 240

Query: 241  SKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLS 300
            SKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLS
Sbjct: 241  SKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLS 300

Query: 301  FLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTEN 360
            FLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTEN
Sbjct: 301  FLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTEN 360

Query: 361  LAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEAT 420
            LAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEAT
Sbjct: 361  LAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEAT 420

Query: 421  KEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPA 480
            KEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPA
Sbjct: 421  KEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPA 480

Query: 481  EDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP 540
            EDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP
Sbjct: 481  EDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP 540

Query: 541  RLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSS 600
            RLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSS
Sbjct: 541  RLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSS 600

Query: 601  PIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPS 660
            PIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPS
Sbjct: 601  PIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPS 660

Query: 661  FPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSS 720
            FPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSS
Sbjct: 661  FPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSS 720

Query: 721  GEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGAS 780
            GEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGAS
Sbjct: 721  GEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGAS 780

Query: 781  VPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNP 840
            VPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNP
Sbjct: 781  VPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNP 840

Query: 841  AWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMS 900
            AWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMS
Sbjct: 841  AWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMS 900

Query: 901  EASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLP 960
            EASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLP
Sbjct: 901  EASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLP 960

Query: 961  SIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADR 1020
            SIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADR
Sbjct: 961  SIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADR 1020

Query: 1021 LVLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGN 1080
            LVLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGN
Sbjct: 1021 LVLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGN 1080

Query: 1081 GSPSPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVE 1140
            GSPSPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVE
Sbjct: 1081 GSPSPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVE 1140

Query: 1141 NFGKRKPLLQAWVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNATATKVANCSLGTATII 1200
            NFGKRKPLLQAWVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNATATKVANCSLGTATII
Sbjct: 1141 NFGKRKPLLQAWVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNATATKVANCSLGTATII 1200

Query: 1201 SENLNNEVMMKKYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLV 1260
            SENLNNEVMMKKYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLV
Sbjct: 1201 SENLNNEVMMKKYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLV 1260

Query: 1261 RVMEETPNILRIPTQVGKKAGKM 1283
            RVMEETPNILRIPTQVGKKAGKM
Sbjct: 1261 RVMEETPNILRIPTQVGKKAGKM 1283


>gi|50363230 RAB11 family interacting protein 1 isoform 2 [Homo
            sapiens]
          Length = 612

 Score = 1212 bits (3135), Expect = 0.0
 Identities = 611/612 (99%), Positives = 611/612 (99%)

Query: 672  MGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALS 731
            MGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALS
Sbjct: 1    MGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALS 60

Query: 732  LSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKL 791
            LSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKL
Sbjct: 61   LSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKL 120

Query: 792  EEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDG 851
            EEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDG
Sbjct: 121  EEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDG 180

Query: 852  EPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLF 911
            EPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLF
Sbjct: 181  EPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLF 240

Query: 912  RMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDER 971
            RMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDER
Sbjct: 241  RMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDER 300

Query: 972  IDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFR 1031
            IDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFR
Sbjct: 301  IDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFR 360

Query: 1032 LQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSL 1091
            LQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSL
Sbjct: 361  LQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSL 420

Query: 1092 DNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQA 1151
            DNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQA
Sbjct: 421  DNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQA 480

Query: 1152 WVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNATATKVANCSLGTATIISENLNNEVMMK 1211
            WVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNA ATKVANCSLGTATIISENLNNEVMMK
Sbjct: 481  WVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNAMATKVANCSLGTATIISENLNNEVMMK 540

Query: 1212 KYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILR 1271
            KYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILR
Sbjct: 541  KYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILR 600

Query: 1272 IPTQVGKKAGKM 1283
            IPTQVGKKAGKM
Sbjct: 601  IPTQVGKKAGKM 612


>gi|50363228 RAB11 family interacting protein 1 isoform 1 [Homo
           sapiens]
          Length = 649

 Score = 1060 bits (2741), Expect = 0.0
 Identities = 544/552 (98%), Positives = 544/552 (98%)

Query: 1   MSLMVSAGRGLGAVWSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERS 60
           MSLMVSAGRGLGAVWSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERS
Sbjct: 1   MSLMVSAGRGLGAVWSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERS 60

Query: 61  LGAPVWREEATFELPSLLSSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQGR 120
           LGAPVWREEATFELPSLLSSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQGR
Sbjct: 61  LGAPVWREEATFELPSLLSSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQGR 120

Query: 121 RKTQWYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGK 180
           RKTQWYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGK
Sbjct: 121 RKTQWYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGK 180

Query: 181 NKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPT 240
           NKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPT
Sbjct: 181 NKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPT 240

Query: 241 SKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLS 300
           SKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLS
Sbjct: 241 SKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLS 300

Query: 301 FLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTEN 360
           FLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTEN
Sbjct: 301 FLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTEN 360

Query: 361 LAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEAT 420
           LAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEAT
Sbjct: 361 LAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEAT 420

Query: 421 KEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPA 480
           KEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPA
Sbjct: 421 KEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPA 480

Query: 481 EDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP 540
           EDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP
Sbjct: 481 EDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP 540

Query: 541 RLEVSPEAQPTA 552
           RL        TA
Sbjct: 541 RLHPVKPMNATA 552



 Score =  223 bits (569), Expect = 7e-58
 Identities = 138/248 (55%), Positives = 155/248 (62%), Gaps = 18/248 (7%)

Query: 1041 APSEQTTEFGIHKPHLGKSSSLDKQLPGPS----GGEEEKPMGNGSPSPPPGTSLDNPVP 1096
            A SE T E    K    + SSL   + G      G E E P+        PG   +  + 
Sbjct: 415  ANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPL------TVPGREKEGMLM 468

Query: 1097 SPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRV-ENFGKRKPLLQAWVSP 1155
               P E         S    D    S  ++    + +GS+  + E+    +P  +     
Sbjct: 469  GVKPGED-------ASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKS 521

Query: 1156 SETHPVSAQPGAGTGSAKHRLHPVKPMNATATKVANCSLGTATIISENLNNEVMMKKYSP 1215
                P+S+     T + K RLHPVKPMNATATKVANCSLGTATIISENLNNEVMMKKYSP
Sbjct: 522  EPRPPISSPRAPQTRAVKPRLHPVKPMNATATKVANCSLGTATIISENLNNEVMMKKYSP 581

Query: 1216 SDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRIPTQ 1275
            SDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRIPTQ
Sbjct: 582  SDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRIPTQ 641

Query: 1276 VGKKAGKM 1283
            VGKKAGKM
Sbjct: 642  VGKKAGKM 649


>gi|24308075 RAB11 family interacting protein 5 (class I) [Homo
           sapiens]
          Length = 653

 Score =  265 bits (676), Expect = 3e-70
 Identities = 193/501 (38%), Positives = 264/501 (52%), Gaps = 52/501 (10%)

Query: 15  WSPTHVQVTVLQARGLRAK--GPGGTSDAYAVIQVGKEKYATSVSERSLGAPVWREEATF 72
           W PTHVQVTVL+ARGLR K  G G TSDAY VIQVG+EKY+TSV E++ G P WREE +F
Sbjct: 16  WLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVEKTHGCPEWREECSF 75

Query: 73  ELP-----SLL-----SSGPA-------AAATLQLTVLHRALLGLDKFLGRAEVDLRDLH 115
           ELP      LL      +GPA       AA  L LT +HR+L+G+DKFLG+A V L ++ 
Sbjct: 76  ELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGVDKFLGQATVALDEVF 135

Query: 116 RDQGRRKTQWYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKD 175
                + TQWYKL SKPGKK+KERGEIEV IQF RNN++ASMFDLSMKDK R+PF K++D
Sbjct: 136 GAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDLSMKDKPRSPFSKIRD 195

Query: 176 KIKGKNKDSGSDTASAIIPSTTPSVDSDDESVVK-DKKKKSKIKTLLSKSNLQK------ 228
           K+KGK K    ++ASAI+PS+    D D  S+ K  K K   ++  L KS+L +      
Sbjct: 196 KMKGKKK-YDLESASAILPSSAIE-DPDLGSLGKMGKAKGFFLRNKLRKSSLTQSNTSLG 253

Query: 229 --TPLSQSMSVLPTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQL 286
             + LS +   L    P   LL     +S W   +   +S+ +  + +HKRT S +  Q+
Sbjct: 254 SDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLFTHKRTYSDEANQM 313

Query: 287 NQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSP 346
                  P +  L   G L    D  SRS++C+NG+H+Y E+P+     + S   S PS 
Sbjct: 314 R----VAPPRALLDLQGHL----DAASRSSLCVNGSHIYNEEPQGPVRHRSSISGSLPSS 365

Query: 347 KGFRKKHLFSSTENLAA--GSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRP---- 400
              +      S E   +   +W   +     SS+  L +       K +   +  P    
Sbjct: 366 GSLQAVSSRFSEEGPRSTDDTWPRGSRSNS-SSEAVLGQEELSAQAKVLAPGASHPGEEE 424

Query: 401 -APLVSGDLRENMAP--ANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLT 457
            A L  G   +   P  A+SEA  E KE  + E R+  +       + +++   G     
Sbjct: 425 GARLPEGKPVQVATPIVASSEAVAE-KEGARKEERKPRMGLFHHHHQGLSRSELGRRSSL 483

Query: 458 VPGREKEGMLMGVKPGEDASG 478
               EK G ++G  P   +SG
Sbjct: 484 ---GEKGGPILGASPHHSSSG 501



 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 49/161 (30%), Positives = 85/161 (52%), Gaps = 14/161 (8%)

Query: 1119 HHTSTAESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPGAGTGSAKHRLHP 1178
            HH+S+ E + K++  G   R      +KP      SP    P+SA P  G+   K     
Sbjct: 496  HHSSSGEEKAKSSWFGL--REAKDPTQKP------SPHPVKPLSAAPVEGSPDRKQSRSS 547

Query: 1179 VK-PMNATATKVANCSLGTATIISE-----NLNNEVMMKKYSPSDPAFAYAQLTHDELIQ 1232
            +   +++   K+   + G+   +++      + +   +K  +  D +  Y  LTHDELI 
Sbjct: 548  LSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSAVLDQSAKYYHLTHDELIS 607

Query: 1233 LVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRIP 1273
            L+L+++  +S+++  V+ELE YID LLVR+ME +P +L+IP
Sbjct: 608  LLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQIP 648


>gi|7662394 RAB11 family interacting protein 2 (class I) [Homo
           sapiens]
          Length = 512

 Score =  253 bits (646), Expect = 8e-67
 Identities = 160/345 (46%), Positives = 208/345 (60%), Gaps = 21/345 (6%)

Query: 15  WSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERSLGAPVWREEATFEL 74
           W PTHVQVTVLQA+ L+ KG  GT+D Y +IQ+GKEKY+TSV+E++L  PVW+EEA+FEL
Sbjct: 10  WFPTHVQVTVLQAKDLKPKGKSGTNDTYTIIQLGKEKYSTSVAEKTL-EPVWKEEASFEL 68

Query: 75  PSLLSSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQGRRKTQWYKLKSKPGK 134
           P LL  G      L L V+HR+L+GLDKFLG+  ++L D+  D+ RRKT+W++L+SK GK
Sbjct: 69  PGLLIQGSPEKYILFLIVMHRSLVGLDKFLGQVAINLNDIFEDKQRRKTEWFRLESKQGK 128

Query: 135 KDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKG-KNKDSGSDTASAII 193
           + K RGEI+V+IQFMRNNMTASMFDLSMKDK+R+PF KLKDK+KG KN  + SDT+SAII
Sbjct: 129 RIKNRGEIKVNIQFMRNNMTASMFDLSMKDKTRSPFAKLKDKMKGRKNDGTFSDTSSAII 188

Query: 194 PST-TPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPTSKPEKVLLRPGD 252
           PST  P  +S+  S     K K K   LL    L     + SMS L  S      L+ G 
Sbjct: 189 PSTHMPDANSEFSSGEIQMKSKPKKPFLLGPQRLSS---AHSMSDLSGSHMSSEKLKAGT 245

Query: 253 FQS------QWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLSFLGGLR 306
                    Q D      ES S      H+RT S D  ++NQ +  + + E L F     
Sbjct: 246 IGQTHLLGHQLDSFGTVPESGSLKS--PHRRTLSFDTSKMNQPDSIVDEGE-LCF----G 298

Query: 307 SKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRK 351
            +ND    +NV  +    +   P  K   ++SS +   S   F K
Sbjct: 299 RQNDPF--TNVTASLPQKFATLPRKKNPFEESSETWDSSMNLFSK 341



 Score = 83.6 bits (205), Expect = 1e-15
 Identities = 38/69 (55%), Positives = 53/69 (76%)

Query: 1214 SPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRIP 1273
            +P D    Y  LT++E++Q ++K KE + +K+  +RELEDYIDNLLVRVMEETP+ILR+P
Sbjct: 440  NPFDATAGYRSLTYEEVLQELVKHKELLRRKDTHIRELEDYIDNLLVRVMEETPSILRVP 499

Query: 1274 TQVGKKAGK 1282
             +  +KAGK
Sbjct: 500  YEPSRKAGK 508


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 113/528 (21%), Positives = 204/528 (38%), Gaps = 55/528 (10%)

Query: 417 SEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDA 476
           ++ T+E  E ++ E+           K++  K  EG       G E+E       P E+A
Sbjct: 464 TQVTEEVTEEEEKEA-----------KEEEGKEEEGGEEEEAEGGEEE---TKSPPAEEA 509

Query: 477 SGP---AEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAP 533
           + P   A+  V+   K  A   S +        +V+  E    P  +    PP    ++P
Sbjct: 510 ASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPP--EAKSP 567

Query: 534 QTRAVKPRLEV-SPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQS--SE 590
           +    K   EV SPE    A+ P+  ++ S          ++ V  E    A+ +S   E
Sbjct: 568 EKEEAKSPAEVKSPE---KAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE 624

Query: 591 SPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSS 650
                + + SP  A   T    +S       + +    P   K+ ++ E+ +  P    S
Sbjct: 625 EAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKS--PEKAKS 682

Query: 651 VLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEE----EL 706
            + +  K P    +   E++          EK  S ++ E   PE+ ++  +EE    E 
Sbjct: 683 PVKAEAKSPEKAKSPVKEEA-------KSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEK 735

Query: 707 PRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARD 766
            + P K++  SP   ++ E    L + S  A +P  E A         +A S V+ + + 
Sbjct: 736 AKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVK- 794

Query: 767 AAEEVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAAL 826
           + E+   PL   A  P  +  + K EE+   +++++K  + +V    +   EE       
Sbjct: 795 SPEKAKSPLKEDAKAP--EKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPK 852

Query: 827 LVEGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPA-DHL 885
             E   S  +E          A   E P+ P  E+ +  +V  P  +   A    A D  
Sbjct: 853 TEEKKDSKKEE----------APKKEAPK-PKVEEKKEPAVEKPKESKVEAKKEEAEDKK 901

Query: 886 LLPSQE-ESFSEVPMSEASSAKD-TPLFRMEGEDALVTQYQSKASDHE 931
            +P+ E E+ ++V + E +  K+ T + + E +DA   +    A   E
Sbjct: 902 KVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKE 949



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 107/531 (20%), Positives = 189/531 (35%), Gaps = 44/531 (8%)

Query: 364  GSWKEPAEGGGLSSDRQLSE---SSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEAT 420
            G  +E AEGG   +    +E   S  K++   +   +  PA   S +  E  +PA  ++ 
Sbjct: 488  GGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSP 547

Query: 421  KEAK-----------ESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMG 469
            ++AK           E+K PE   +   + +   +     ++ E       +  E     
Sbjct: 548  EKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP 607

Query: 470  VKPGEDASGPAE--DLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPI 527
            VK  E+A  PAE    V+   K  A V S + +     E+ +  E    PE K E + P 
Sbjct: 608  VK--EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE-KEEAKSPE 664

Query: 528  SSPRAPQTRAVKPRLEVSP---EAQPTARLPSPTDSPSSLPPLPSS--SGQASVPSELGH 582
             +    +  A  P    SP   EA+   +  SP    +  P    S    +A  P +   
Sbjct: 665  KAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKS 724

Query: 583  GADTQSSESPSVFSSLSSPIAAPISTSTPIESWPL-VDRGQAKSEGPPLLPKAELQTESL 641
                ++       S +     +P    +P ++  L V   +AK+      P  E      
Sbjct: 725  PVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKT------PAKEEARSPA 778

Query: 642  TPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGR 701
               P    S +    K P    +   ED+          EK     E E   P + E   
Sbjct: 779  DKFPEKAKSPVKEEVKSPEKAKSPLKEDA-------KAPEKEIPKKE-EVKSPVKEEEKP 830

Query: 702  QEEELPRFPCK-KQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLV 760
            QE ++   P K +++ +P++ + +E   +    +    +P  ++    +  +E    S V
Sbjct: 831  QEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKV 890

Query: 761  ESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEA 820
            E+K  +A ++   P P   +   ++       +    + K +    K    S+    +EA
Sbjct: 891  EAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEA 950

Query: 821  VAGAALLVEGHSSCPQELNPAWSVAGNASD---GEPPESPHAEDSERESVT 868
                    E  +  P+E  P         D    + P  P AE +E+ S T
Sbjct: 951  APEKKDTKEEKAKKPEE-KPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSST 1000



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 72/373 (19%), Positives = 132/373 (35%), Gaps = 46/373 (12%)

Query: 128  LKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGKNKDSGSD 187
            +K++    +K +  ++ + +      +    +    +K+++P   +K++ K   K     
Sbjct: 670  VKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSP---VKEEAKSPEKAKSPV 726

Query: 188  TASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPTSKPEKVL 247
               A  P    S   ++    +  K   K KTL  KS   KTP  +         PEK  
Sbjct: 727  KEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKA- 785

Query: 248  LRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLSFLGGLRS 307
                               S   + +     A + LK+    +   P+KE       +  
Sbjct: 786  ------------------KSPVKEEVKSPEKAKSPLKE----DAKAPEKE-------IPK 816

Query: 308  KNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTE--NLAAGS 365
            K +V S          V +++P  K E + +  +     K   KK      E        
Sbjct: 817  KEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEE 876

Query: 366  WKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAP-ANSEATK--- 421
             KEPA      S  +  +   +D  K  T     PA +   +++E+  P   +E  K   
Sbjct: 877  KKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKV---EVKEDAKPKEKTEVAKKEP 933

Query: 422  ---EAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASG 478
               +AKE  KP  ++ +       K++ AK  E E P T    +++   +  +P +  + 
Sbjct: 934  DDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPE-EKPKTEAKAKEDDKTLSKEPSKPKAE 992

Query: 479  PAEDLVRRSEKDT 491
             AE      +KD+
Sbjct: 993  KAEKSSSTDQKDS 1005



 Score = 34.7 bits (78), Expect = 0.60
 Identities = 83/426 (19%), Positives = 146/426 (34%), Gaps = 42/426 (9%)

Query: 555 PSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIES 614
           P P   P  LP +PS S    V SE       +S +   +    +         +   E 
Sbjct: 417 PIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEK 476

Query: 615 WPLVDRGQAKSEG--------------PPLLPKAELQTESLTPVPNSGSSVLGSLFKQPS 660
               + G+ +  G              PP    A  + E+ +PV            K P+
Sbjct: 477 EAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEA--------KSPA 528

Query: 661 FPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSS 720
             A    ++           EK  S  + E   P + ++  +EE       K  + + S 
Sbjct: 529 -EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSP 587

Query: 721 GEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGAS 780
            + +    A + S + A SPV E A        ++A S V+ +A+  AE  +P     A 
Sbjct: 588 AKEEAKSPAEAKSPEKAKSPVKEEAKS-----PAEAKSPVKEEAKSPAEVKSPE---KAK 639

Query: 781 VPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNP 840
            P+ +    K  E   +  K++ K+ ++   S      ++   A   V+  +  P++   
Sbjct: 640 SPTKEE--AKSPEKAKSPEKEEAKSPEKAK-SPVKAEAKSPEKAKSPVKAEAKSPEKAKS 696

Query: 841 AWSVAGNASDGEPPESPHAEDSER-ESVTTPGPATCGAPASPADHLLLPSQEESFSEVPM 899
              V   A   E  +SP  E+++  E   +P       P         P +EE+ S    
Sbjct: 697 --PVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKS----PVKEEAKSPEKA 750

Query: 900 SEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPL-SDLQLVSDFKSPIMADLNLS 958
                AK   +   E +     + +S A         P+  +++     KSP+  D    
Sbjct: 751 KSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAP 810

Query: 959 LPSIPE 964
              IP+
Sbjct: 811 EKEIPK 816


>gi|148806908 fibronectin type III domain containing 1 [Homo sapiens]
          Length = 1894

 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 191/889 (21%), Positives = 310/889 (34%), Gaps = 170/889 (19%)

Query: 329  PEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKD 388
            P  +       PS   SP+G   K L    +N      K  A GG     +  ++ + + 
Sbjct: 480  PSPRAPASSQHPSVPASPQGRNAKDLLLDLKN------KILANGGAPRKPQLRAKKAEEL 533

Query: 389  SLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAK 448
             L+S  +             RE+ +P +   T++ K + +P SR     S++   +   +
Sbjct: 534  DLQSTEITGEEEL-----GSRED-SPMSPSDTQDQKRTLRPPSRHGH--SVVAPGRTAVR 585

Query: 449  GSEGENPLTVPGREKEGMLMGV--KPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFE 506
                  P    G +K G  +    +PG   S  A      S + T+   S   +SLN  +
Sbjct: 586  ARMPALPRR-EGVDKPGFSLATQPRPGAPPSASASPAHHASTQGTSHRPSLP-ASLNDND 643

Query: 507  DVQITEPEAEPESK------SEPRPPISSPRAPQTRAVKPRLEVSPEAQPTA---RLP-- 555
             V   E E    S       ++PRP +S  R   +  ++ R  V P A+P +   R P  
Sbjct: 644  LVDSDEDERAVGSLHPKGAFAQPRPALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHS 703

Query: 556  --SPTDSPSSLPP----------------LPSSSGQASVPSELGHGADTQSSESPSVFSS 597
              +  DS +S PP                 P  S   S   + G  A   +S +PS  S+
Sbjct: 704  GAAEEDSSASAPPSRLSPPHGGSSRLLPTQPHLSSPLSKGGKDGEDAPATNSNAPS-RST 762

Query: 598  LSSPIAAPISTSTPIESWPLVDRGQAKSEG--PPLLPKAELQTESLTPVPNSGSSVLGSL 655
            +SS +++ +S+ T +        G++  +G       +AE   ++L   P SG      L
Sbjct: 763  MSSSVSSHLSSRTQVSEGAEASDGESHGDGDREDGGRQAEATAQTLRARPASGHF---HL 819

Query: 656  FKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQD 715
             +   F AN G   S     R    + ++S           P++       PR P     
Sbjct: 820  LRHKPFAAN-GRSPSRFSIGRGPRLQPSSS-----------PQSTVPSRAHPRVPSHSDS 867

Query: 716  YSP-SSG----EAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEE 770
            +   SSG    E  E P   ++ +D   S   +  + G  DL         S  R A+  
Sbjct: 868  HPKLSSGIHGDEEDEKPLPATVVNDHVPSSSRQPISRGWEDLR-------RSPQRGASLH 920

Query: 771  VAPPLPMGASVPSID--------SMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVA 822
               P+P        D        S+  K +++  +   D +    +              
Sbjct: 921  RKEPIPENPKSTGADTHPQGKYSSLASKAQDVQQSTDADTEGHSPKAQPGSTDRHASPAR 980

Query: 823  GAALLVEGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPA 882
              A   + H S P+ + P     G A   +PP  P    S+      PGP +  A  SP+
Sbjct: 981  PPAARSQQHPSVPRRMTP-----GRAPQQQPP--PPVATSQHH----PGPQSRDAGRSPS 1029

Query: 883  DHLLLPSQEESFSEVPMSEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQ 942
               L  S  ++    P S+  S   +  +       L T  Q++  D +G   D  ++++
Sbjct: 1030 QPRL--SLTQAGRPRPTSQGRSHSSSDPYTASSRGMLPTALQNQDEDAQGSYDDDSTEVE 1087

Query: 943  LVSDFKSPIMA----DLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGA 998
               D ++P  A    +   SLP   +V S           GD     G  A         
Sbjct: 1088 -AQDVRAPAHAARAKEAAASLPKHQQVESP----TGAGAGGDHRSQRGHAAS-------- 1134

Query: 999  LSLGLVVPCPERGKGPSGEADRLVLGEGLCDFRLQAP---------QASVTAPSEQTTEF 1049
                     P R   P G   R  +       + + P         Q SV+A  ++  + 
Sbjct: 1135 ---------PARPSRPGGPQSRARVPSRAAPGKSEPPSKRPLSSKSQQSVSAEDDEEEDA 1185

Query: 1050 GIHKPHLGKSSSLDKQLP------GPSGG---------EEEKPM-------GNGSP---- 1083
            G  K   GK   L   +P       P GG         EE +P        G+ +P    
Sbjct: 1186 GFFKG--GKEDLLSSSVPKWPSSSTPRGGKDADGSLAKEEREPAIALAPRGGSLAPVKRP 1243

Query: 1084 -SPPPGTS-----LDNPVPSPSPSEIFPV--THSFPS-SAHSDTHHTST 1123
              PPPG+S     + + +P  S + + PV  TH +P  +  +   H ST
Sbjct: 1244 LPPPPGSSPRASHVPSRLPPRSAATVSPVAGTHPWPQYTTRAPPGHFST 1292



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 8/100 (8%)

Query: 452 GENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRR--SEKDTAAVVSRQGSSLNLFEDVQ 509
           G   LT PG     ++ G++PGE          RR       A +V+   +S    E  Q
Sbjct: 407 GAKSLTYPGDTTSALVDGLQPGERYLFKIRATNRRGLGPHSKAFIVAMPTTSKADVE--Q 464

Query: 510 ITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQ 549
            TE   +PE   +P P   SPRAP + +  P +  SP+ +
Sbjct: 465 NTEDNGKPE---KPEPSSPSPRAPAS-SQHPSVPASPQGR 500


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 121/563 (21%), Positives = 198/563 (35%), Gaps = 87/563 (15%)

Query: 180 KNKDSGSDTASAIIPSTTPSVDSDDESVV-KDKKKKSKIKTLLSKSNLQKTPLSQSMSVL 238
           +N++S S ++S+   ST   + S   S   ++ +KK K+K   +K N  K          
Sbjct: 121 ENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKD--NKKNRTKKK-------- 170

Query: 239 PTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHK-RTASTDLKQLNQVNFTLPK-- 295
           PT KP  V                 DE+ S  D    K  T  T   Q N+V+ T PK  
Sbjct: 171 PTPKPPVV-----------------DEAGSGLDNGDFKVTTPDTSTTQHNKVS-TSPKIT 212

Query: 296 -KEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSP-SPKGFRKKH 353
             + ++    L   +D    +++ +N         E   E K+++ ++   S  G  K  
Sbjct: 213 TAKPINPRPSLPPNSDTSKETSLTVN--------KETTVETKETTTTNKQTSTDGKEKTT 264

Query: 354 LFSSTENLAAGSWKEPAEGGG-LSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENM 412
               T+++   S K+ A     L+     +E++TK    ++T P   P P    +     
Sbjct: 265 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP--ALTTPK-EPTPTTPKEPASTT 321

Query: 413 APANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKP 472
               +  T ++  +   E   ++  S  T  K+ A  +  E   T P            P
Sbjct: 322 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 381

Query: 473 GEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPI----- 527
               S P       + K+ A    ++ +     E    T  E  P +  EP P       
Sbjct: 382 TTTKSAPT------TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 435

Query: 528 --------SSPRAPQTRAVKPRLEVSPE--AQPTARLPSPTDSPSSLPPLPSSSGQASVP 577
                   ++P+ P     K     +P+  A  T + PSPT      P  P+ +   S P
Sbjct: 436 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT-----TPKEPAPTTTKSAP 490

Query: 578 SELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQ 637
           +     A T +  +P+     S       + +TP E  P   +  A     P  PK    
Sbjct: 491 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-----PTTPKEPAP 545

Query: 638 TESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEK----------NTSSL 687
           T    P P +      +  K+P+    K T  +   +   T  EK           T+  
Sbjct: 546 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 605

Query: 688 ELEESLPEQPETGRQEEELPRFP 710
           EL  + PE+P     EE  P  P
Sbjct: 606 ELAPTTPEEPTPTTPEEPAPTTP 628



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 78/385 (20%), Positives = 131/385 (34%), Gaps = 39/385 (10%)

Query: 336 KDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTL 395
           K+ +P+++  P     K    +T   A  + KEPA     S+     E S   + +    
Sbjct: 463 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 522

Query: 396 PSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENP 455
               PAP           PA +   + A  + K  +  ++     T  K+ A  +  E  
Sbjct: 523 TPKEPAPTTP------KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 576

Query: 456 LTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEA 515
            T P +     L    P + A    E     + ++ A     + +     E    T   A
Sbjct: 577 PTTPKK-----LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 631

Query: 516 EPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQAS 575
            P +  EP P  ++P+ P              A  T + P+PT    + P  P    + +
Sbjct: 632 APNTPKEPAP--TTPKEP--------------APTTPKEPAPTTPKETAPTTP----KGT 671

Query: 576 VPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAE 635
            P+ L   A T + + P+      +    P ST T  +  P   +G A     P  PK  
Sbjct: 672 APTTLKEPAPT-TPKKPAPKELAPTTTKEPTST-TCDKPAPTTPKGTA-----PTTPKEP 724

Query: 636 LQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPE 695
             T    P P +      +  K+P+    K      +  T   G    TS  +   + P+
Sbjct: 725 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPK 783

Query: 696 QPETGRQEEELPRFPCKKQDYSPSS 720
           +      +E  P  P K    +P +
Sbjct: 784 ETAPTTPKEPAPTTPKKPAPTTPET 808



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 95/494 (19%), Positives = 161/494 (32%), Gaps = 66/494 (13%)

Query: 239 PTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEG 298
           P  K  K ++   +   +    +N++ SSS+S   S          + +  N  L KK  
Sbjct: 99  PNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKK-- 156

Query: 299 LSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSST 358
                 L+ K++  +R+           ++P  K  + D + S                 
Sbjct: 157 ------LKVKDNKKNRTK----------KKPTPKPPVVDEAGSG---------------- 184

Query: 359 ENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPA-PLVSGDLRENMAPANS 417
             L  G +K        +S  Q ++ ST   + +    + RP+ P  S   +E     N 
Sbjct: 185 --LDNGDFKVTTPD---TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNK 239

Query: 418 EATKEAKES------------KKPESRRSSLLSLMTGKKDVAKGSEG-ENPLTVPGREKE 464
           E T E KE+            +K  S + +     T  KD+A  S+    P        +
Sbjct: 240 ETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK 299

Query: 465 GMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPR 524
           G  +        + P E      ++ T   +    S+    ++   T  ++ P +  EP 
Sbjct: 300 GPALTTPKEPTPTTPKEPASTTPKEPTPTTIK---SAPTTPKEPAPTTTKSAPTTPKEPA 356

Query: 525 PPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGA 584
           P  +   AP T   +P    + E  PT    +PT      P  P        P+     A
Sbjct: 357 PTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA----PTTPKEPA 411

Query: 585 DTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPV 644
            T   E         +P     + +TP E  P   +  A     P  PK    T    P 
Sbjct: 412 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA-----PTTPKEPAPTTPKEPA 466

Query: 645 PNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEE 704
           P +      +  K+P+    K    +       T     T+  E   +  ++P     +E
Sbjct: 467 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 526

Query: 705 ELPRFPCKKQDYSP 718
             P  P K    +P
Sbjct: 527 PAPTTPKKPAPTTP 540



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%)

Query: 1028 CDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEE-KPMGNGSPSPP 1086
            CD   Q  +     P  ++    +H P    SS   K+ P PSG  +  K     SP PP
Sbjct: 43   CDCDAQCKKYDKCCPDYESFCAEVHNPTSPPSS---KKAPPPSGASQTIKSTTKRSPKPP 99

Query: 1087 PGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGR 1138
                    + S   +E   V+ +  SS+ S +  +S+   + K++   +A R
Sbjct: 100  NKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANR 151



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 150/785 (19%), Positives = 259/785 (32%), Gaps = 88/785 (11%)

Query: 376  SSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSS 435
            SS +    S    ++KS T  S +P        +      + E T+E   S+  ES  SS
Sbjct: 74   SSKKAPPPSGASQTIKSTTKRSPKPP----NKKKTKKVIESEEITEEHSVSENQESSSSS 129

Query: 436  LLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVV 495
              S  +    + K    +N  +   RE +  L  VK  +      ++  ++       VV
Sbjct: 130  --SSSSSSSTIRKIKSSKN--SAANRELQKKLK-VKDNK------KNRTKKKPTPKPPVV 178

Query: 496  SRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLP 555
               GS L+   D ++T P+    S ++     +SP+    + + PR  + P +  T++  
Sbjct: 179  DEAGSGLDN-GDFKVTTPDT---STTQHNKVSTSPKITTAKPINPRPSLPPNSD-TSKET 233

Query: 556  SPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPIST--STPIE 613
            S T +  +      ++      S  G    T + E+ S+    S+   AP S   + P  
Sbjct: 234  SLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI-EKTSAKDLAPTSKVLAKPTP 292

Query: 614  SWPLVDRGQAKS---EGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDS 670
                  +G A +   E  P  PK    T    P P    + + S    P  PA   T+ +
Sbjct: 293  KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP----TTIKSAPTTPKEPAPTTTKSA 348

Query: 671  -LMGRTRETGTEKNTSSLELEESLPEQ-----PETGRQEEELPRFPCKKQDYSPSSGEAQ 724
                +     T K  +    +E  P       P T +     P+ P       P+    +
Sbjct: 349  PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 408

Query: 725  EVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPM--GASVP 782
            E P   +       +P            +  A +  +  A  A ++ AP  P     + P
Sbjct: 409  E-PAPTTPKEPTPTTPKEPAPT-----TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP 462

Query: 783  SIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAW 842
               +     E      ++    T K    S    T+E    A    +   + P+E +P  
Sbjct: 463  KEPAPTTTKEPSPTTPKEPAPTTTK----SAPTTTKEP---APTTTKSAPTTPKEPSPTT 515

Query: 843  SVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLL-PSQEESFSEVPMSE 901
            +     +    P+ P     ++ + TTP       P  PA      P+        P + 
Sbjct: 516  TKEPAPTT---PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 572

Query: 902  ASSAKDTP--LFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSL 959
              +A  TP  L     E    T  +  A      L+    +    +  + P       + 
Sbjct: 573  KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 632

Query: 960  PSIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEAD 1019
            P+ P+  +     +       +         + T   G     L  P P   K P     
Sbjct: 633  PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP----- 687

Query: 1020 RLVLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPH----LGKSSSLDKQLPGPSGGEEE 1075
                          AP+      +++ T     KP      G + +  K+ P P+  +E 
Sbjct: 688  --------------APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE-PAPTTPKEP 732

Query: 1076 KPMGNGSPSPPPGTSLDNPVPS----PSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKAT 1131
             P    +P     T+L  P P+    P+P E+ P T   P+S  SD    +T +     T
Sbjct: 733  APT---TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 789

Query: 1132 AEGSA 1136
             +  A
Sbjct: 790  PKEPA 794



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 49/253 (19%), Positives = 87/253 (34%), Gaps = 23/253 (9%)

Query: 489  KDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP--RLEVSP 546
            K+ A   ++  +S    +    T  E  P +  EP P      AP T    P    EVS 
Sbjct: 759  KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 818

Query: 547  EA---QPTARLPSPTDSPSSLPPLPSSSGQASVPSELG-HGADTQSSESPSVFSSLSSPI 602
                 +PT    SP +S   L   P+     + P E G     T ++  P + ++     
Sbjct: 819  PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 878

Query: 603  AAPISTSTP--IESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGS-----SVLGSL 655
                  +TP    + P + +  A +       K    T  +T      +     + L + 
Sbjct: 879  TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 938

Query: 656  FKQPSFPANKGT----------EDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEE 705
               P     K T          E++   + R T ++  T   +     P++P + ++ + 
Sbjct: 939  TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT 998

Query: 706  LPRFPCKKQDYSP 718
            +PR    K   +P
Sbjct: 999  MPRVRKPKTTPTP 1011


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 121/563 (21%), Positives = 198/563 (35%), Gaps = 87/563 (15%)

Query: 180 KNKDSGSDTASAIIPSTTPSVDSDDESVV-KDKKKKSKIKTLLSKSNLQKTPLSQSMSVL 238
           +N++S S ++S+   ST   + S   S   ++ +KK K+K   +K N  K          
Sbjct: 162 ENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKD--NKKNRTKKK-------- 211

Query: 239 PTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHK-RTASTDLKQLNQVNFTLPK-- 295
           PT KP  V                 DE+ S  D    K  T  T   Q N+V+ T PK  
Sbjct: 212 PTPKPPVV-----------------DEAGSGLDNGDFKVTTPDTSTTQHNKVS-TSPKIT 253

Query: 296 -KEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSP-SPKGFRKKH 353
             + ++    L   +D    +++ +N         E   E K+++ ++   S  G  K  
Sbjct: 254 TAKPINPRPSLPPNSDTSKETSLTVN--------KETTVETKETTTTNKQTSTDGKEKTT 305

Query: 354 LFSSTENLAAGSWKEPAEGGG-LSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENM 412
               T+++   S K+ A     L+     +E++TK    ++T P   P P    +     
Sbjct: 306 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP--ALTTPK-EPTPTTPKEPASTT 362

Query: 413 APANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKP 472
               +  T ++  +   E   ++  S  T  K+ A  +  E   T P            P
Sbjct: 363 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 422

Query: 473 GEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPI----- 527
               S P       + K+ A    ++ +     E    T  E  P +  EP P       
Sbjct: 423 TTTKSAPT------TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 476

Query: 528 --------SSPRAPQTRAVKPRLEVSPE--AQPTARLPSPTDSPSSLPPLPSSSGQASVP 577
                   ++P+ P     K     +P+  A  T + PSPT      P  P+ +   S P
Sbjct: 477 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT-----TPKEPAPTTTKSAP 531

Query: 578 SELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQ 637
           +     A T +  +P+     S       + +TP E  P   +  A     P  PK    
Sbjct: 532 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-----PTTPKEPAP 586

Query: 638 TESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEK----------NTSSL 687
           T    P P +      +  K+P+    K T  +   +   T  EK           T+  
Sbjct: 587 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 646

Query: 688 ELEESLPEQPETGRQEEELPRFP 710
           EL  + PE+P     EE  P  P
Sbjct: 647 ELAPTTPEEPTPTTPEEPAPTTP 669



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 78/385 (20%), Positives = 131/385 (34%), Gaps = 39/385 (10%)

Query: 336 KDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTL 395
           K+ +P+++  P     K    +T   A  + KEPA     S+     E S   + +    
Sbjct: 504 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 563

Query: 396 PSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENP 455
               PAP           PA +   + A  + K  +  ++     T  K+ A  +  E  
Sbjct: 564 TPKEPAPTTP------KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 617

Query: 456 LTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEA 515
            T P +     L    P + A    E     + ++ A     + +     E    T   A
Sbjct: 618 PTTPKK-----LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 672

Query: 516 EPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQAS 575
            P +  EP P  ++P+ P              A  T + P+PT    + P  P    + +
Sbjct: 673 APNTPKEPAP--TTPKEP--------------APTTPKEPAPTTPKETAPTTP----KGT 712

Query: 576 VPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAE 635
            P+ L   A T + + P+      +    P ST T  +  P   +G A     P  PK  
Sbjct: 713 APTTLKEPAPT-TPKKPAPKELAPTTTKEPTST-TCDKPAPTTPKGTA-----PTTPKEP 765

Query: 636 LQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPE 695
             T    P P +      +  K+P+    K      +  T   G    TS  +   + P+
Sbjct: 766 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPK 824

Query: 696 QPETGRQEEELPRFPCKKQDYSPSS 720
           +      +E  P  P K    +P +
Sbjct: 825 ETAPTTPKEPAPTTPKKPAPTTPET 849



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 95/494 (19%), Positives = 161/494 (32%), Gaps = 66/494 (13%)

Query: 239 PTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEG 298
           P  K  K ++   +   +    +N++ SSS+S   S          + +  N  L KK  
Sbjct: 140 PNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKK-- 197

Query: 299 LSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSST 358
                 L+ K++  +R+           ++P  K  + D + S                 
Sbjct: 198 ------LKVKDNKKNRTK----------KKPTPKPPVVDEAGSG---------------- 225

Query: 359 ENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPA-PLVSGDLRENMAPANS 417
             L  G +K        +S  Q ++ ST   + +    + RP+ P  S   +E     N 
Sbjct: 226 --LDNGDFKVTTPD---TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNK 280

Query: 418 EATKEAKES------------KKPESRRSSLLSLMTGKKDVAKGSEG-ENPLTVPGREKE 464
           E T E KE+            +K  S + +     T  KD+A  S+    P        +
Sbjct: 281 ETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK 340

Query: 465 GMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPR 524
           G  +        + P E      ++ T   +    S+    ++   T  ++ P +  EP 
Sbjct: 341 GPALTTPKEPTPTTPKEPASTTPKEPTPTTIK---SAPTTPKEPAPTTTKSAPTTPKEPA 397

Query: 525 PPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGA 584
           P  +   AP T   +P    + E  PT    +PT      P  P        P+     A
Sbjct: 398 PTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA----PTTPKEPA 452

Query: 585 DTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPV 644
            T   E         +P     + +TP E  P   +  A     P  PK    T    P 
Sbjct: 453 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA-----PTTPKEPAPTTPKEPA 507

Query: 645 PNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEE 704
           P +      +  K+P+    K    +       T     T+  E   +  ++P     +E
Sbjct: 508 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 567

Query: 705 ELPRFPCKKQDYSP 718
             P  P K    +P
Sbjct: 568 PAPTTPKKPAPTTP 581



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%)

Query: 1028 CDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEE-KPMGNGSPSPP 1086
            CD   Q  +     P  ++    +H P    SS   K+ P PSG  +  K     SP PP
Sbjct: 84   CDCDAQCKKYDKCCPDYESFCAEVHNPTSPPSS---KKAPPPSGASQTIKSTTKRSPKPP 140

Query: 1087 PGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGR 1138
                    + S   +E   V+ +  SS+ S +  +S+   + K++   +A R
Sbjct: 141  NKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANR 192



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 150/785 (19%), Positives = 259/785 (32%), Gaps = 88/785 (11%)

Query: 376  SSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSS 435
            SS +    S    ++KS T  S +P        +      + E T+E   S+  ES  SS
Sbjct: 115  SSKKAPPPSGASQTIKSTTKRSPKPP----NKKKTKKVIESEEITEEHSVSENQESSSSS 170

Query: 436  LLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVV 495
              S  +    + K    +N  +   RE +  L  VK  +      ++  ++       VV
Sbjct: 171  --SSSSSSSTIRKIKSSKN--SAANRELQKKLK-VKDNK------KNRTKKKPTPKPPVV 219

Query: 496  SRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLP 555
               GS L+   D ++T P+    S ++     +SP+    + + PR  + P +  T++  
Sbjct: 220  DEAGSGLDN-GDFKVTTPDT---STTQHNKVSTSPKITTAKPINPRPSLPPNSD-TSKET 274

Query: 556  SPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPIST--STPIE 613
            S T +  +      ++      S  G    T + E+ S+    S+   AP S   + P  
Sbjct: 275  SLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI-EKTSAKDLAPTSKVLAKPTP 333

Query: 614  SWPLVDRGQAKS---EGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDS 670
                  +G A +   E  P  PK    T    P P    + + S    P  PA   T+ +
Sbjct: 334  KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP----TTIKSAPTTPKEPAPTTTKSA 389

Query: 671  -LMGRTRETGTEKNTSSLELEESLPEQ-----PETGRQEEELPRFPCKKQDYSPSSGEAQ 724
                +     T K  +    +E  P       P T +     P+ P       P+    +
Sbjct: 390  PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 449

Query: 725  EVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPM--GASVP 782
            E P   +       +P            +  A +  +  A  A ++ AP  P     + P
Sbjct: 450  E-PAPTTPKEPTPTTPKEPAPT-----TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP 503

Query: 783  SIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAW 842
               +     E      ++    T K    S    T+E    A    +   + P+E +P  
Sbjct: 504  KEPAPTTTKEPSPTTPKEPAPTTTK----SAPTTTKEP---APTTTKSAPTTPKEPSPTT 556

Query: 843  SVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLL-PSQEESFSEVPMSE 901
            +     +    P+ P     ++ + TTP       P  PA      P+        P + 
Sbjct: 557  TKEPAPTT---PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 613

Query: 902  ASSAKDTP--LFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSL 959
              +A  TP  L     E    T  +  A      L+    +    +  + P       + 
Sbjct: 614  KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 673

Query: 960  PSIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEAD 1019
            P+ P+  +     +       +         + T   G     L  P P   K P     
Sbjct: 674  PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP----- 728

Query: 1020 RLVLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPH----LGKSSSLDKQLPGPSGGEEE 1075
                          AP+      +++ T     KP      G + +  K+ P P+  +E 
Sbjct: 729  --------------APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE-PAPTTPKEP 773

Query: 1076 KPMGNGSPSPPPGTSLDNPVPS----PSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKAT 1131
             P    +P     T+L  P P+    P+P E+ P T   P+S  SD    +T +     T
Sbjct: 774  APT---TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 830

Query: 1132 AEGSA 1136
             +  A
Sbjct: 831  PKEPA 835



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 49/253 (19%), Positives = 87/253 (34%), Gaps = 23/253 (9%)

Query: 489  KDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP--RLEVSP 546
            K+ A   ++  +S    +    T  E  P +  EP P      AP T    P    EVS 
Sbjct: 800  KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 859

Query: 547  EA---QPTARLPSPTDSPSSLPPLPSSSGQASVPSELG-HGADTQSSESPSVFSSLSSPI 602
                 +PT    SP +S   L   P+     + P E G     T ++  P + ++     
Sbjct: 860  PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 919

Query: 603  AAPISTSTP--IESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGS-----SVLGSL 655
                  +TP    + P + +  A +       K    T  +T      +     + L + 
Sbjct: 920  TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 979

Query: 656  FKQPSFPANKGT----------EDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEE 705
               P     K T          E++   + R T ++  T   +     P++P + ++ + 
Sbjct: 980  TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT 1039

Query: 706  LPRFPCKKQDYSP 718
            +PR    K   +P
Sbjct: 1040 MPRVRKPKTTPTP 1052


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 113/547 (20%), Positives = 194/547 (35%), Gaps = 58/547 (10%)

Query: 402 PLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGR 461
           PLV G LR+N     +    +A  + + ++  SSLL + +     AK  E +     P  
Sbjct: 16  PLVLGFLRDNQLSEVANKFAKATGATQQDANASSLLDIYSFWLKSAKVPERKLQANGPVA 75

Query: 462 EKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQG-----SSLNLFEDVQITEPEAE 516
           +K          ED+S   E++     K  A    R G     ++    E     E   +
Sbjct: 76  KKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDD 135

Query: 517 PESKSEPRPPISSPRAPQTRAVK--PRLEVS-------------PEAQPTARLPSPTDSP 561
            + + + + P+     PQ +A K  P+   S             P+ Q     P    + 
Sbjct: 136 DDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQ 195

Query: 562 SSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPIST--------STPIE 613
           +  PP P+ +       +    + + SS S S  S      A P  T          P++
Sbjct: 196 TKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVK 255

Query: 614 SWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQP-----SFPANKGTE 668
           +     R  + SE      + E Q + +   P   SSV       P     + P  K  E
Sbjct: 256 AATTPTRKSSSSEDSS-SDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVE 314

Query: 669 DSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPF 728
                 + E  ++++ SS E E+  P +    +   + P  P KK   S S     +   
Sbjct: 315 KQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPP--PAKKAAESSSDSSDSD--- 369

Query: 729 ALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMM 788
               SS+   +P     AG  ++  ++     +S A   A   AP  P+G     +    
Sbjct: 370 ----SSEDDEAP--SKPAGTTKNSSNKPAVTTKSPAVKPA--AAPKQPVGGGQKLLTRKA 421

Query: 789 RKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNA 848
                   +   +++KTKK V+ ++     +A A AAL      S P +  P  S   ++
Sbjct: 422 DSSSSEEESSSSEEEKTKKMVATTK----PKATAKAAL------SLPAKQAPQGS-RDSS 470

Query: 849 SDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDT 908
           SD +   S   E+   +S     P      A+P+        +   S    S+ SS ++ 
Sbjct: 471 SDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEE 530

Query: 909 PLFRMEG 915
              + +G
Sbjct: 531 EKLKGKG 537



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 66/273 (24%), Positives = 112/273 (41%), Gaps = 40/273 (14%)

Query: 199 SVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPTSKP-------EKVLLRPG 251
           S DS D    +D +  SK       S+ +    ++S +V P + P       +K+L R  
Sbjct: 362 SSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKA 421

Query: 252 DFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDV 311
           D  S      +E+ESSS+ +  + K  A+T  K   +   +LP K+     G   S +D 
Sbjct: 422 DSSS------SEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQ--GSRDSSSDS 473

Query: 312 LSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAE 371
            S S+          E+ E K        +S  + K   +K    +  +  A + K  AE
Sbjct: 474 DSSSS----------EEEEEK--------TSKSAVKKKPQKVAGGAAPSKPASAKKGKAE 515

Query: 372 GGGLSSDRQLSESSTKDSLKSMTLPSYRP-APLVSGDLRENMAPANSEATKEAKESKKPE 430
               SS    SE   ++ LK    P  RP AP  +G     +   N +A K ++E ++ E
Sbjct: 516 SSNSSSSDDSSEEE-EEKLKGKGSP--RPQAPKANG--TSALTAQNGKAAKNSEEEEE-E 569

Query: 431 SRRSSLLSLMTGKKDVAKGSEGENPLTVPGREK 463
            ++++++   +G     K +E       P  +K
Sbjct: 570 KKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKK 602



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 90/505 (17%), Positives = 173/505 (34%), Gaps = 50/505 (9%)

Query: 125 WYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGKNKDS 184
           W K    P +K +  G +    +  +   ++   D S +++        K  +  K    
Sbjct: 57  WLKSAKVPERKLQANGPVAKKAK--KKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGL 114

Query: 185 GSDTASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPL---------SQSM 235
               A+A    ++ S +S D+   +D+KK+   K +  ++   K P          S S 
Sbjct: 115 PPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSS 174

Query: 236 SVLPTSKPEKVLLRPGDFQSQWD------------------EDDNEDESSSASDVMSHKR 277
           S     K +K  + P   ++Q                       +   SSS+SD    ++
Sbjct: 175 SEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEK 234

Query: 278 TASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKD 337
            A+T  K       T+PKK+ ++    +++      +S+   + +    E+ +   + K 
Sbjct: 235 AAATPKK-------TVPKKQVVA-KAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKP 286

Query: 338 SSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPS 397
              SS P P     K    +     A   ++P E    SSD   S+SS+++  K  T   
Sbjct: 287 GPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDE--SDSSSEEEKKPPTKAV 344

Query: 398 YRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLT 457
              A       ++    ++  +  ++ E  +  S+ +      + K  V   S    P  
Sbjct: 345 VSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAA 404

Query: 458 VPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEP 517
            P +   G    +    D+S   E+     E+ T  +V+           + +   +A  
Sbjct: 405 APKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQ 464

Query: 518 ESK-SEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASV 576
            S+ S      SS    + +  K  ++  P+       PS           P+S+ +   
Sbjct: 465 GSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSK----------PASAKKGKA 514

Query: 577 PSELGHGADTQSSESPSVFSSLSSP 601
            S     +D  S E         SP
Sbjct: 515 ESSNSSSSDDSSEEEEEKLKGKGSP 539



 Score = 30.8 bits (68), Expect = 8.7
 Identities = 38/148 (25%), Positives = 59/148 (39%), Gaps = 44/148 (29%)

Query: 1033 QAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGS---------P 1083
            +AP  + T P+ +++          + SS D++       E++KPM N            
Sbjct: 251  KAPVKAATTPTRKSSS--------SEDSSSDEE------EEQKKPMKNKPGPYSSVPPPS 296

Query: 1084 SPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFG 1143
            +PPP  SL    P  +  +  PV  S  SS  SD    S++E +K               
Sbjct: 297  APPPKKSLGTQPPKKAVEKQQPVESSEDSSDESD----SSSEEEK--------------- 337

Query: 1144 KRKPLLQAWVSPSETHPVSAQPGAGTGS 1171
              KP  +A VS + T P  A+  A + S
Sbjct: 338  --KPPTKAVVSKATTKPPPAKKAAESSS 363


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 107/488 (21%), Positives = 172/488 (35%), Gaps = 64/488 (13%)

Query: 456  LTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEA 515
            +TV   E    +  V   E+ +      + +      A  S + ++L +   V ITE + 
Sbjct: 912  VTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAI--TVPITEEDG 969

Query: 516  EPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTD--SPSSLPPLPS--SS 571
             PE    P   + +P  P T AV+      P A P A +P+P +  SP++  P P   +S
Sbjct: 970  TPEGPVTPATTVHAPEEPDTAAVRVSTPEEP-ASPAAAVPTPEEPTSPAAAVPTPEEPTS 1028

Query: 572  GQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLL 631
              A+VP      +   +  +P   +S ++ +  P   ++P  + P  +   + +   P  
Sbjct: 1029 PAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP-T 1087

Query: 632  PKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEE 691
            P+      +  P P           ++P+ PA                T +  +S     
Sbjct: 1088 PEEPTSPAAAVPTP-----------EEPTSPA------------AAVPTPEEPASPAAAV 1124

Query: 692  SLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRD 751
              PE+P +       P  P       P+  E+     A+    + A SP    AA     
Sbjct: 1125 PTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESA-SP----AAAVPTP 1179

Query: 752  LESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEM---GLNLRKDQKKTKKR 808
             ES + + V +   +       P    ASVP+  +M+  LEE      ++   ++     
Sbjct: 1180 AESASFAAVVATLEE-------PTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLA 1232

Query: 809  VSFSEQLFTEEAVAGAALLVEGHSSCPQELNP--AWSVAGNASDGEPPESPHAEDSERES 866
             + S         A    L E  SS    L P    S A +    E P SP A  S  E 
Sbjct: 1233 AAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEE 1292

Query: 867  VTTPGPA---------------TCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLF 911
              +P  A               T   PA PA   + P +E S   VP    S+  D+   
Sbjct: 1293 PASPAAAVPTPEVAAIPAASVPTPEVPAIPA-AAVPPMEEVSPIGVPFLGVSAHTDSVPI 1351

Query: 912  RMEGEDAL 919
              EG   L
Sbjct: 1352 SEEGTPVL 1359



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 41/194 (21%), Positives = 69/194 (35%), Gaps = 11/194 (5%)

Query: 1034 APQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDN 1093
            +P A+V  P E  +      P     +  +   P  +    E+P       P P  S   
Sbjct: 1106 SPAAAVPTPEEPAS------PAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASA 1159

Query: 1094 PVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQAWV 1153
             V  P+P E      + P+ A S +     A  ++  +   S   V         L+ + 
Sbjct: 1160 AVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAAS---VPTPAAMVATLEEFT 1216

Query: 1154 SPSETHPVSAQPGAGTGSAKHRLHPVKPMNATATKVANCSLGTATIISENLNNEV--MMK 1211
            SP+ + P S +P +   +  +   P  P  A  T     S   A +  E L++    +  
Sbjct: 1217 SPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPT 1276

Query: 1212 KYSPSDPAFAYAQL 1225
               P+ PA A + L
Sbjct: 1277 PEEPASPAAAVSNL 1290


>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
           [Homo sapiens]
          Length = 1481

 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 135/587 (22%), Positives = 214/587 (36%), Gaps = 93/587 (15%)

Query: 163 KDKSR---NPFGKLKDKIKGKNKDSGSDT-----ASAIIPSTTPSVDS--DDESVVKDKK 212
           K+KS+   +  G +KD+I G +K S  +T     A     S+  S  S    E   K+++
Sbjct: 130 KEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERE 189

Query: 213 KKSKIKTLLSKSNLQKTPLSQSMSVLPTSKPEKVLLRPGDFQSQ----------WDEDDN 262
            KS  K        ++TP S      P  +      +  D   Q           D D +
Sbjct: 190 LKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLS 249

Query: 263 EDESSSASDVMSHKRT-ASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCING 321
              S ++S+  S+K++  ST  +Q    + + P KE  ++    RS +    R       
Sbjct: 250 PSRSHTSSNYDSYKKSPGSTSRRQ----SVSPPYKEPSAYQSSTRSPSPYSRRQ----RS 301

Query: 322 NHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHL-FSSTENLAAGSWKEPAEGGGLSSDRQ 380
              Y  +  +  E   S    SPSP G R+    F S  +L+             S    
Sbjct: 302 VSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPA 361

Query: 381 LSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLM 440
            S  S+  S K  +    R + +    L     P NS    E    KK E   ++  + M
Sbjct: 362 YSRHSSSHSKKKRSSSRSRHSSISPVRL-----PLNSSLGAELSRKKK-ERAAAAAAAKM 415

Query: 441 TGKKDVAKGSEGENPLTVPGREK---EGMLMGVKPGE-------DASGPAEDLVR----- 485
            GK+  +KGS    P+ +P +E    E    G++  +       + S P  +LV      
Sbjct: 416 DGKE--SKGS----PVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLN 469

Query: 486 ---RSEKDTAAVVSRQGSSLNLFEDVQI-----TEPEAEPESKSEPRPPISSPRAPQTRA 537
              ++  DT  V   + S  +L +D++      ++P A  E    P+   +S +  +T  
Sbjct: 470 TEVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEK--ETPP 527

Query: 538 VKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSS 597
             P +   P   PT   P  T     LPP+P+   Q  +P             S   FS 
Sbjct: 528 PLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPPLP------------PSQPAFSQ 575

Query: 598 LSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFK 657
           + +   + +  ST   S       QA S+ PP+    + Q      +P+  +S L  L  
Sbjct: 576 VPASSTSTLPPST--HSKTSAVSSQANSQ-PPVQVSVKTQVSVTAAIPHLKTSTLPPLPL 632

Query: 658 QPSFPANKGTEDSLMGRTRET------GTEKNTSSLELEESLPEQPE 698
            P  P      D  M   +ET        EK   +  L   LP  PE
Sbjct: 633 PPLLPG-----DDDMDSPKETLPSKPVKKEKEQRTRHLLTDLPLPPE 674


>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
           [Homo sapiens]
          Length = 1490

 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 135/587 (22%), Positives = 214/587 (36%), Gaps = 93/587 (15%)

Query: 163 KDKSR---NPFGKLKDKIKGKNKDSGSDT-----ASAIIPSTTPSVDS--DDESVVKDKK 212
           K+KS+   +  G +KD+I G +K S  +T     A     S+  S  S    E   K+++
Sbjct: 130 KEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERE 189

Query: 213 KKSKIKTLLSKSNLQKTPLSQSMSVLPTSKPEKVLLRPGDFQSQ----------WDEDDN 262
            KS  K        ++TP S      P  +      +  D   Q           D D +
Sbjct: 190 LKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLS 249

Query: 263 EDESSSASDVMSHKRT-ASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCING 321
              S ++S+  S+K++  ST  +Q    + + P KE  ++    RS +    R       
Sbjct: 250 PSRSHTSSNYDSYKKSPGSTSRRQ----SVSPPYKEPSAYQSSTRSPSPYSRRQ----RS 301

Query: 322 NHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHL-FSSTENLAAGSWKEPAEGGGLSSDRQ 380
              Y  +  +  E   S    SPSP G R+    F S  +L+             S    
Sbjct: 302 VSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPA 361

Query: 381 LSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLM 440
            S  S+  S K  +    R + +    L     P NS    E    KK E   ++  + M
Sbjct: 362 YSRHSSSHSKKKRSSSRSRHSSISPVRL-----PLNSSLGAELSRKKK-ERAAAAAAAKM 415

Query: 441 TGKKDVAKGSEGENPLTVPGREK---EGMLMGVKPGE-------DASGPAEDLVR----- 485
            GK+  +KGS    P+ +P +E    E    G++  +       + S P  +LV      
Sbjct: 416 DGKE--SKGS----PVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLN 469

Query: 486 ---RSEKDTAAVVSRQGSSLNLFEDVQI-----TEPEAEPESKSEPRPPISSPRAPQTRA 537
              ++  DT  V   + S  +L +D++      ++P A  E    P+   +S +  +T  
Sbjct: 470 TEVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEK--ETPP 527

Query: 538 VKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSS 597
             P +   P   PT   P  T     LPP+P+   Q  +P             S   FS 
Sbjct: 528 PLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPPLP------------PSQPAFSQ 575

Query: 598 LSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFK 657
           + +   + +  ST   S       QA S+ PP+    + Q      +P+  +S L  L  
Sbjct: 576 VPASSTSTLPPST--HSKTSAVSSQANSQ-PPVQVSVKTQVSVTAAIPHLKTSTLPPLPL 632

Query: 658 QPSFPANKGTEDSLMGRTRET------GTEKNTSSLELEESLPEQPE 698
            P  P      D  M   +ET        EK   +  L   LP  PE
Sbjct: 633 PPLLPG-----DDDMDSPKETLPSKPVKKEKEQRTRHLLTDLPLPPE 674



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 56/254 (22%), Positives = 91/254 (35%), Gaps = 36/254 (14%)

Query: 514  EAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQ 573
            E   +  S P+ P  +P  PQ  A      + P   P  R P P   P   PP P   G 
Sbjct: 1229 ENNSDKNSGPQGPRRTPTMPQEEAAACPPHILP---PEKRPPEPPGPPPPPPPPPLVEGD 1285

Query: 574  -ASVPSELGHGADTQSSESPSVFSSLSSPIAAP-------ISTSTPIE--SWPLVDRGQA 623
             +S P EL        + + ++   LS P A P            P+E  + P  +R   
Sbjct: 1286 LSSAPQEL------NPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYG 1339

Query: 624  KSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKN 683
             ++GP     A + T+     P    S++ +L K  +F  +       +    E+ + + 
Sbjct: 1340 NTDGPETGFSA-IDTDERNSGPALTESLVQTLVKNRTFSGS-------LSHLGESSSYQG 1391

Query: 684  TSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGE 743
            T S++     P   +       L   P   Q +  + G +  V     + ++  +   GE
Sbjct: 1392 TGSVQ----FPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSV-----VHAETKLQNYGE 1442

Query: 744  LAAGGDRDLESQAG 757
            L  G      S AG
Sbjct: 1443 LGPGTTGASSSGAG 1456


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 185/887 (20%), Positives = 305/887 (34%), Gaps = 143/887 (16%)

Query: 384  SSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGK 443
            S T   L SM +     A   +G L       ++  T   K S  P +    ++ + T  
Sbjct: 2806 SETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTA- 2864

Query: 444  KDVAKGSEGENPLT------VPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSR 497
                  SEG   LT       P    E   +   P  D S P       S   T A    
Sbjct: 2865 ------SEGSTLLTSIPVSTTPVASSEASTLSTTP-VDTSIPVTTSTEGSSSPTTA---- 2913

Query: 498  QGSSLNLFEDVQITEP------EAEPESKSEPRPPISSP---RAPQTRAVKPRLEVSPEA 548
            +G+S+ +    +++ P         P + SE     ++P   R P T + +     SP  
Sbjct: 2914 EGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEA--SSSPTT 2971

Query: 549  QPTARLPSPTDSPSSLP-------PLPSSSGQASVPSELGHGADT------QSSESPSVF 595
                 +P  T      P        +P +S +AS  S       T      ++S SP+  
Sbjct: 2972 AEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTA 3031

Query: 596  SSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSL 655
                 PI+ P   STP+ S P+       S  P  +P+A   T S TPV ++   V  + 
Sbjct: 3032 EGTGIPISTPSEGSTPLTSIPV-------STTPVAIPEAS--TLSTTPVDSNSPVVTSTE 3082

Query: 656  FKQPSFPANKGTEDSLM----GRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPC 711
                  PA +GT   +     G T  TG   +T+           P T      L   P 
Sbjct: 3083 VSSSPTPA-EGTSMPISTYSEGSTPLTGVPVSTT-----------PVTSSAISTLSTTPV 3130

Query: 712  KKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEV 771
                   +S EA   P     +S+G   P    + G          +++   + D+    
Sbjct: 3131 DTSTPVTTSTEAHSSP----TTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSA 3186

Query: 772  AP---PLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLV 828
             P     P+  S  +  S   +   +  +   +       V  S    T  A + A++L 
Sbjct: 3187 TPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSN---TPVASSEASIL- 3242

Query: 829  EGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLP 888
               S+ P + N   + +  AS   P        +E  S+ T  P+    P        L 
Sbjct: 3243 ---STTPVDSNTPLTTSTEASSSPPT-------AEGTSMPTSTPSEGSTP--------LT 3284

Query: 889  SQEESFSEVPMSEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFK 948
            S   S + V  SE S+   TP          VT Y S+AS    +           S+  
Sbjct: 3285 SMPVSTTTVASSETSTLSTTPA----DTSTPVTTY-SQASSSPPIADGTSMPTSTYSEGS 3339

Query: 949  SPIMADLNLSLPSIPEVASDDERIDQVE-DDGDQVEDDGETAKSSTLDIGALSLGLVVPC 1007
            +P+    N+S  + P V+S+   +     D    V    E + S T      + G  +P 
Sbjct: 3340 TPLT---NMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTT-----AEGTSIPT 3391

Query: 1008 PERGKGPSGEADRLVLGEGLCDFRLQAPQAS-------VTAPSEQTTEFGIHKPHLGKSS 1060
                +G +  A   V    +    +     +       VT  +E ++      P + + +
Sbjct: 3392 SSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSS-----PTIAEGT 3446

Query: 1061 SLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLD------NPVPSPSPSEIFPVTHSFPSSA 1114
            SL    P  +  E   P+     S  P  S +       PV + +P      T+S P++A
Sbjct: 3447 SL----PTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTA 3502

Query: 1115 HSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPGAGTGSAKH 1174
               +  TSTA        EGS           P+  +  S   T PV +     T S++ 
Sbjct: 3503 EVTSMPTSTA-------GEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFV-TSSSQA 3554

Query: 1175 RLHPVKPMNATATKVANCSLGTATIISENLNNEVM--MKKYSPSDPA 1219
               P   +  T  +++  S G++++ +  L++  +   +  +PS P+
Sbjct: 3555 SSSPA-TLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPS 3600



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 158/837 (18%), Positives = 287/837 (34%), Gaps = 95/837 (11%)

Query: 370  AEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKP 429
            AEG  + +    SE ST   L+SM + +   A   +  L       +   T   + S  P
Sbjct: 2559 AEGTSMPTSTY-SEGSTP--LRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSP 2615

Query: 430  ESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEK 489
             + + + + + T   +V+         T+P    E   +   P +  +     LV  S  
Sbjct: 2616 TTAKDTSMPIST-PSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRT-----LVTTSTG 2669

Query: 490  DTAAVVSRQGSSLNLFEDVQITEPE----------AEPESKSEPRPPISSPRAPQTRAVK 539
             +++  + +GSS+      + + P           A  E+ +    P+ +   P T + +
Sbjct: 2670 TSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTS-TPVTTSAE 2728

Query: 540  PRLEVSPEAQPTARLPSPTDSPSSLPP-----LPSSSGQAS------VPSELGHGADTQS 588
                 +     + R+ +P+D  + L       LP +S +AS      V + +     T++
Sbjct: 2729 ASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEA 2788

Query: 589  SESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPL-LPKAELQTESLTPVPNS 647
            S SP+     S P + P  TSTP+ S P+     A SE   L     +  T   T    S
Sbjct: 2789 SSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKAS 2848

Query: 648  GSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELP 707
             S         P   A++G+       T  T    +T+ +   E+      T   +  +P
Sbjct: 2849 SSPTTAEGIVVPISTASEGS-------TLLTSIPVSTTPVASSEA--STLSTTPVDTSIP 2899

Query: 708  RFPCKKQDYSPSSGEAQEVPFALSLSSDGAVS-PVGELAAGGDRDLESQAGSLVESKARD 766
                 +   SP++ E   +P    +S+   VS P+  +         S+A +L  +   D
Sbjct: 2900 VTTSTEGSSSPTTAEGTSMP----ISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPV-D 2954

Query: 767  AAEEVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAG--A 824
                V       +S  + +     +   G          ++R   +    +   VA   A
Sbjct: 2955 TRTPVTTSAEASSSPTTAEGTSMPISTPG----------ERRTPLTSMSVSTMPVASSEA 3004

Query: 825  ALLVEGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADH 884
            + L    +     +  +   + + +  E    P +  SE  +  T  P +    A P   
Sbjct: 3005 STLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEAS 3064

Query: 885  LLLPSQEESFSEVPMSEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLV 944
             L  +  +S S V  S   S+  TP    EG    ++ Y   ++   G+   P+S   + 
Sbjct: 3065 TLSTTPVDSNSPVVTSTEVSSSPTP---AEGTSMPISTYSEGSTPLTGV---PVSTTPVT 3118

Query: 945  SDFKSPIMADLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLV 1004
            S   S +         S P   S +        +G  +     +  S+ L    +S  LV
Sbjct: 3119 SSAISTL--STTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLV 3176

Query: 1005 VPCPERGKG-----------PSGEADRLVLGEGLCDFRLQAPQASVTAPSE---QTTEFG 1050
            V   +                S EA      EG        P   +T  +      T   
Sbjct: 3177 VSSEDSTLSATPVDTSTPVTTSTEATSSTTAEG-TSIPTSTPSEGMTPLTSVPVSNTPVA 3235

Query: 1051 IHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDNPVPS--PSPSEIFPVTH 1108
              +  +  ++ +D   P  +  E      + SP    GTS+    PS   +P    PV+ 
Sbjct: 3236 SSEASILSTTPVDSNTPLTTSTE-----ASSSPPTAEGTSMPTSTPSEGSTPLTSMPVST 3290

Query: 1109 SFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQP 1165
            +  +S+ + T  T+ A++    T    A          P+      P+ T+   + P
Sbjct: 3291 TTVASSETSTLSTTPADTSTPVTTYSQA------SSSPPIADGTSMPTSTYSEGSTP 3341



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 171/885 (19%), Positives = 289/885 (32%), Gaps = 102/885 (11%)

Query: 376  SSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEA--------------TK 421
            S+    S ++ + S    + P  R  PL +  L      ANSEA              T 
Sbjct: 2667 STGTSSSPTTAEGSSMPTSTPGERSTPLTN-ILVSTTLLANSEASTLSTTPVDTSTPVTT 2725

Query: 422  EAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAE 481
             A+ S  P +   + + + T        S+G  PLT        +L+   P    +    
Sbjct: 2726 SAEASSSPTTAEGTSMRISTP-------SDGSTPLT-------SILVSTLP---VASSEA 2768

Query: 482  DLVRRSEKDTAAVVSRQGSSLNLFEDVQITE-PEAEPESKSEP-------RPPISSPRAP 533
              V  +  DT+  V+    + +     ++T  P + P   S P         P++S  A 
Sbjct: 2769 STVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAG 2828

Query: 534  QTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPS 593
             T +  P    +P    T    SPT +   + P+ ++S  +++ + +       +S   S
Sbjct: 2829 -TLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEAS 2887

Query: 594  VFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTE------SLTPVPNS 647
              S+     + P++TST   S P    G +     P+   +E+ T       S  PV  S
Sbjct: 2888 TLSTTPVDTSIPVTTSTEGSSSPTTAEGTSM----PISTPSEVSTPLTSILVSTVPVAGS 2943

Query: 648  GSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELP 707
             +S L +       P     E S    T E GT        +  S P +  T      + 
Sbjct: 2944 EASTLSTTPVDTRTPVTTSAEASSSPTTAE-GT-------SMPISTPGERRTPLTSMSVS 2995

Query: 708  RFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDA 767
              P    + S  S    +    ++ S++ + SP      G      S+ GS   +    +
Sbjct: 2996 TMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSE-GSTPLTSIPVS 3054

Query: 768  AEEVAPPLPMGASVPSIDSMMRKL--EEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAA 825
               VA P     S   +DS    +   E+  +    +  +    ++SE       V  + 
Sbjct: 3055 TTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVST 3114

Query: 826  LLVEGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHL 885
              V   +       P  +     +  E   SP   +      +TP   +      P   +
Sbjct: 3115 TPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTM 3174

Query: 886  LLPSQEESFSEVPMSEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVS 945
            L+ S E+S       + S+   T         A  T   +         S+ ++ L  V 
Sbjct: 3175 LVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTP------SEGMTPLTSVP 3228

Query: 946  DFKSPIMADLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSL---- 1001
               +P+ A    S+ S   V S+       E        +G +  +ST   G+  L    
Sbjct: 3229 VSNTPV-ASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMP 3287

Query: 1002 --GLVVPCPERGKGPSGEADRLVLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKS 1059
                 V   E     +  AD               P A  T+    T   G   P    S
Sbjct: 3288 VSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEG-STPLTNMS 3346

Query: 1060 SSLDKQLPGPSGGEEEKPMGNGSP-------SPPPGTSLDNPVPSPSPSE------IFPV 1106
             S    +   +      P+   +P       S  P T+    +P+ SPSE        PV
Sbjct: 3347 FSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPV 3406

Query: 1107 THSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQAWVS----PSETHPVS 1162
            + +   S+  +T  T+  +S    T    A       +   L  +  S    P    P+S
Sbjct: 3407 STTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLS 3466

Query: 1163 AQPGAGTGSAKHRLHPV---------KPMNATATKVANCSLGTAT 1198
              P A + ++     PV          P N++ T     S+ T+T
Sbjct: 3467 TTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTST 3511



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 172/877 (19%), Positives = 278/877 (31%), Gaps = 127/877 (14%)

Query: 358  TENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANS 417
            T +  A S    AEG  LS+    + S     L  M L         +  L    A  N 
Sbjct: 248  TISAQASSSPTTAEGPSLSNS---APSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNI 304

Query: 418  EATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDAS 477
                  + S  P +   + +   T        +EG  PLT                   S
Sbjct: 305  PVITSTEASSSPTTAEGTSIPTSTY-------TEGSTPLT-------------------S 338

Query: 478  GPAEDL-VRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEP---ESKSEPRPPISSPRAP 533
             PA  + V  SE  T ++     S+L        TEP + P   E+ S     +S    P
Sbjct: 339  TPASTMPVATSEMSTLSITPVDTSTLVTTS----TEPSSLPTTAEATSMLTSTLSEGSTP 394

Query: 534  QTRA-VKPRLEVSPEAQPTARLPSPTDS----PSSLPPLPSSSGQASVPSELGHGADTQS 588
             T   V   L  S EA  T+ +P  + +     S     P+++   S+ +       T  
Sbjct: 395  LTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPL 454

Query: 589  SESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTE--------- 639
            +  P   + ++S  A+ +ST TP++S   V      S  PP      + T          
Sbjct: 455  TSMPVSTTPVASSEASNLST-TPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPL 513

Query: 640  -----SLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLP 694
                 S  PV +S +S L +     S P    +E S    T E  +   ++  E    L 
Sbjct: 514  TSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLT 573

Query: 695  EQPETGR-----QEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGD 749
              P + R     +       P     +  +S EA     + S +++G   P    +  G 
Sbjct: 574  NMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEAS----SSSTTAEGTSMPTSTYSERGT 629

Query: 750  RDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRV 809
              + S + S     + +A+     P+     V +                     T +  
Sbjct: 630  T-ITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEAT------------SSSTTAEGT 676

Query: 810  SFSEQLFTEEAVAGAAL-----LVEGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSER 864
            S     +TE +    ++     LV    +      P  +     +  E   SP   D   
Sbjct: 677  SMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGAS 736

Query: 865  ESVTTPGPATCGAPASPADHLLLPSQEES-FSEVPM---------SEASSAKDT------ 908
               +TP   +    + P    LL S E S  S  P+         +EAS +  T      
Sbjct: 737  MPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSM 796

Query: 909  PLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASD 968
            P+        L+T      +      +  LS   +  D  SP+     +S    P   + 
Sbjct: 797  PISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPV--DSNSPVTTSTEVSSSPTPAEGTS 854

Query: 969  DERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLV-VPCPERGKGPSGEADRLVLGEGL 1027
                   E           T   +T  I  LS   V    P      +  +     G  +
Sbjct: 855  MPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSM 914

Query: 1028 CDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPP 1087
                       +T+  + TT     +     ++ +D   P  +  E        SP+   
Sbjct: 915  PTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTE-----ATSSPTTAE 969

Query: 1088 GTSLDNPVPS--PSPSEIFPVTHSFPSSAHSDTHH-----------TSTAESQKKATAEG 1134
            GTS+    PS   +P    PV+H+  +++ + T             TST  S    TAEG
Sbjct: 970  GTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEG 1029

Query: 1135 SAGRVENFGK------RKPLLQAWVSPSETHPVSAQP 1165
            ++       +      R P+    V+ SET  +S  P
Sbjct: 1030 TSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTP 1066



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 187/913 (20%), Positives = 309/913 (33%), Gaps = 148/913 (16%)

Query: 266  SSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVY 325
            SS AS + +     ST +    + + +    EG S      S+   L  S   I  +   
Sbjct: 761  SSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTS---IPVSITP 817

Query: 326  LEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESS 385
            +  PEA      ++P  S SP       + +STE     S   PAEG  + +    + S 
Sbjct: 818  VTSPEAS--TLSTTPVDSNSP-------VTTSTE---VSSSPTPAEGTSMPTS---TYSE 862

Query: 386  TKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKD 445
             +  L SM + +   A      L       ++  T   +    P +   + +   T    
Sbjct: 863  GRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTP--- 919

Query: 446  VAKGSEGENPLT------VPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQG 499
                 EG  PLT       P    E   +   P  D S P    V  S + T++  + +G
Sbjct: 920  ----GEGSTPLTSMPDSTTPVVSSEARTLSATP-VDTSTP----VTTSTEATSSPTTAEG 970

Query: 500  SSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTD 559
            +S+          P + P   SE   P++S     T                +  P  T 
Sbjct: 971  TSI----------PTSTP---SEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTS 1017

Query: 560  SPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVD 619
            + +S PP P++ G  S+P+       T  +  P   + ++S   + +ST+    S P+  
Sbjct: 1018 TEASSPP-PTAEG-TSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTT 1075

Query: 620  RGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETG 679
              QA S                      G+S+  S + + S P       + +  + E  
Sbjct: 1076 YSQASSSSTTA----------------DGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEAS 1119

Query: 680  TEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVS 739
            T    S+  ++ S+P    T             +   SP++ E   +P   S  S+G  +
Sbjct: 1120 T---LSTTPVDTSIPVTTST-------------EASSSPTTAEGTSIP--TSPPSEGT-T 1160

Query: 740  PVGELAAGGDRDLESQAGSL----VESKARDAAEEVA---PPLPMGASVPSIDSMMRKLE 792
            P+  +       + S+A +L    V+SK + A    A   PP     S+P+     R   
Sbjct: 1161 PLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTP 1220

Query: 793  EMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGE 852
               + +R                 T  A + A+ L          +  +   + + +  E
Sbjct: 1221 LTSMPVRH----------------TPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAE 1264

Query: 853  PPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLFR 912
                P +  SE  ++ T  P +     SP    LL +  ++   V  S   S+  TP   
Sbjct: 1265 GTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTP--- 1321

Query: 913  MEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDERI 972
             EG     + Y       EG    PL+ + +     + ++A   +S+ S   V +     
Sbjct: 1322 AEGTSMPTSTYS------EG--RTPLTSIPV----NTTLVASSAISILSTTPVDNSTPVT 1369

Query: 973  DQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFRL 1032
               E        +G +  +S    G   L  +         P   ++   L     D   
Sbjct: 1370 TSTEACSSPTTSEGTSMPNSNPSEGTTPLTSI----PVSTTPVVSSEASTLSATPVDTST 1425

Query: 1033 QAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLD 1092
                 S  A S  TT  GI  P    S+  + + P  S      P+ N   S    T   
Sbjct: 1426 PG-TTSAEATSSPTTAEGISIP---TSTPSEGKTPLKSIPVSNTPVANSEAS----TLST 1477

Query: 1093 NPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQAW 1152
             PV S SP     VT +  SS+ +    TS A S     +EGS           P+    
Sbjct: 1478 TPVDSNSP----VVTSTAVSSSPTPAEGTSIAIS---TPSEGSTALTS-----IPVSTTT 1525

Query: 1153 VSPSETHPVSAQP 1165
            V+ SE + +S  P
Sbjct: 1526 VASSEINSLSTTP 1538



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 86/386 (22%), Positives = 121/386 (31%), Gaps = 68/386 (17%)

Query: 358  TENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANS 417
            T +  A S    AEG G+        S+   S+   T P   P    +  L      +NS
Sbjct: 3019 TTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPE---ASTLSTTPVDSNS 3075

Query: 418  EATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLT------VPGREKEGMLMGVK 471
                  + S  P     + + + T        SEG  PLT       P        +   
Sbjct: 3076 PVVTSTEVSSSPTPAEGTSMPISTY-------SEGSTPLTGVPVSTTPVTSSAISTLSTT 3128

Query: 472  PGEDASGPAEDLVRRSEKDTAAVVSR------QGSSLNLFEDVQITEPEAEPESKSEPRP 525
            P + ++         S   T+   S       +GS+   +  V      +  +S     P
Sbjct: 3129 PVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATP 3188

Query: 526  -PISSPRAPQTRAVKPRLEVS---PEAQPTARLPSPTDSPSSLPPLPSSSGQ----ASVP 577
               S+P    T A           P + P+  +   T  P S  P+ SS         V 
Sbjct: 3189 VDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVD 3248

Query: 578  SELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSE----------- 626
            S       T++S SP      S P + P   STP+ S P+     A SE           
Sbjct: 3249 SNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADT 3308

Query: 627  ------------GPPLLPKAELQTE--------------SLTPVPNSGSSVLGSLFKQPS 660
                         PP+     + T               S TPV +S +S L +     S
Sbjct: 3309 STPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTS 3368

Query: 661  FPANKGTEDSLMGRTRETGTEKNTSS 686
             P    TE SL   T E GT   TSS
Sbjct: 3369 TPVTTSTEASLSPTTAE-GTSIPTSS 3393



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 149/723 (20%), Positives = 236/723 (32%), Gaps = 74/723 (10%)

Query: 511  TEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSS 570
            TE     ES S+      S     +    P     P + P+    S T +  S  PLPS 
Sbjct: 113  TESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSF 172

Query: 571  SGQASVPSELGHGA----DTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSE 626
                S+  ++         TQ+S SP+   S + P +     STP+ S P      A SE
Sbjct: 173  EAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSE 232

Query: 627  GPPLL-PKAELQT-------ESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRET 678
               LL    E+ T        S +P    G S+  S     S P  +     ++  + E 
Sbjct: 233  AITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEA 292

Query: 679  GTEKNTSSLE----LEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSS 734
             T   T +      +  +      T  +   +P     +     +S  A  +P A S  S
Sbjct: 293  STLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMS 352

Query: 735  DGAVSPV--GELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLE 792
              +++PV    L             +   S       E + PL    ++P    ++   E
Sbjct: 353  TLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPL---TNMPVSTILVASSE 409

Query: 793  EMGLNLRKDQKK---TKKRVSFSEQLFTEEAVAGAALLVEGH---SSCPQELNP-AWSVA 845
                +      K   T    + S     E+     +   EG    +S P    P A S A
Sbjct: 410  ASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEA 469

Query: 846  GNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPM--SEAS 903
             N S            S   S + P       P S       P    S S +P+  SEAS
Sbjct: 470  SNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEAS 529

Query: 904  SAKDTPLFRMEGEDALVTQYQSKASD-------------HEG---LLSDPLSDLQLVS-- 945
            +   TP   ++    + T  ++ +S               EG   L + P+S   +VS  
Sbjct: 530  TLSTTP---VDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSE 586

Query: 946  -DFKSPIMADLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGETAKS---STLDIGALSL 1001
                S   AD N  + +  E +S     +          + G T  S   ST  + +   
Sbjct: 587  ASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEA 646

Query: 1002 GLVVPCPERGKGPSGEADRLVLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKS-- 1059
              +   P     P   +          +     P ++ T  S   T   ++   +  S  
Sbjct: 647  STLSTTPVDSNTPVTTSTEATSSSTTAE-GTSMPTSTYTEGSTPLTSMPVNTTLVASSEA 705

Query: 1060 SSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDNPVPS--PSPSEIFPVTHSFPSSAHSD 1117
            S+L       S         + SP+   G S+    PS   +P    PV+ +  +S+ + 
Sbjct: 706  STLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEAS 765

Query: 1118 THH-----------TSTAESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPG 1166
            T             TST  S    T EG++  +    +  PLL +   P    PV++ P 
Sbjct: 766  TLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTS--IPVSITPVTS-PE 822

Query: 1167 AGT 1169
            A T
Sbjct: 823  AST 825



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 72/325 (22%), Positives = 114/325 (35%), Gaps = 48/325 (14%)

Query: 358  TENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANS 417
            T +  A S    AEG  L +    SE ST  S+  M L +   A   +  L       ++
Sbjct: 3431 TTSTEASSSPTIAEGTSLPTSTT-SEGSTPLSI--MPLSTTPVASSEASTLSTTPVDTST 3487

Query: 418  EATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLT------VPGREKEGMLMGVK 471
              T  +  +  P +   + +   T         EG  PLT       P    E   +   
Sbjct: 3488 PVTTSSPTNSSPTTAEVTSMPTSTA-------GEGSTPLTNMPVSTTPVASSEASTLSTT 3540

Query: 472  P----------GEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKS 521
            P           + +S PA   V      T +  S   +++ L     +T  EA     S
Sbjct: 3541 PVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTM-LLSSTYVTSSEA-----S 3594

Query: 522  EPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELG 581
             P  P      P T + +     +P    T  + +P++  + L  +P S+   ++ SE G
Sbjct: 3595 TPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTI-SEAG 3653

Query: 582  HGA------------DTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPP 629
              +             TQ S SP      + PI  P   STP+ + P+       SEG  
Sbjct: 3654 TASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGST 3713

Query: 630  LLPKAELQTESLTPVPNSGSSVLGS 654
            L   + + +   TPV  S  ++  S
Sbjct: 3714 LSTPSVVTS---TPVTTSTEAISSS 3735



 Score = 37.7 bits (86), Expect = 0.071
 Identities = 81/348 (23%), Positives = 123/348 (35%), Gaps = 57/348 (16%)

Query: 362  AAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATK 421
            A  S   PAEG  ++     SE ST  +L S+ + +   A      L    A  ++  T 
Sbjct: 1491 AVSSSPTPAEGTSIAISTP-SEGST--ALTSIPVSTTTVASSEINSLSTTPAVTSTPVTT 1547

Query: 422  EAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAE 481
             ++ S  P +   + +   T        SEG  PLT        ML+        S    
Sbjct: 1548 YSQASSSPTTADGTSMQTSTY-------SEGSTPLT--SLPVSTMLVVSSEANTLSTTPI 1598

Query: 482  DLVRRSEKDTAAVVSR--QGSSLN---------LFEDVQI-TEPEAEPESKSEPRPPI-- 527
            D   +    T A  S   +GSS+          L   + + T P A PE+ +    P+  
Sbjct: 1599 DSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDS 1658

Query: 528  SSPRAPQTRAVKPRLEVSPEAQPTA-----RLPSPTDSPSSLPPLPSSSGQAS---VPSE 579
            +SP    T            + PT+     R P  + +  + P   S+    S   V + 
Sbjct: 1659 NSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNS 1718

Query: 580  LGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTE 639
                  T++  SP+     S P + P   +TP+ S P+                      
Sbjct: 1719 TPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPV---------------------- 1756

Query: 640  SLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSL 687
            S TPV +S +S L +     S P    TE +    T E GT   TS+L
Sbjct: 1757 STTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAE-GTSIPTSTL 1803



 Score = 37.4 bits (85), Expect = 0.093
 Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 22/136 (16%)

Query: 1079 GNGSPSPPPGTSLDNPVPSP--SPSEIFPVTHSFPSSAH----------SDTHHTSTAES 1126
            G+ SP+   GTS+    PS   +P    PV+ +   S+           S T  T++ E+
Sbjct: 2022 GSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEA 2081

Query: 1127 QKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNATA 1186
               ATAEGS+  +    +  PLL +   P  T PV A P A T S         P+++ +
Sbjct: 2082 SSSATAEGSSMTISAPSEGSPLLTS--IPLSTTPV-ASPEASTLS-------TTPVDSNS 2131

Query: 1187 TKVANCSLGTATIISE 1202
              + +  + ++ I +E
Sbjct: 2132 PVITSTEVSSSPIPTE 2147



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 150/749 (20%), Positives = 239/749 (31%), Gaps = 123/749 (16%)

Query: 472  PGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPR 531
            P   A G +      SE +T   ++R   S  +    + +     P   S P    S   
Sbjct: 2319 PPPTAEGTSMPTSTSSEGNTP--LTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAG 2376

Query: 532  APQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQAS----VPSELGHGADTQ 587
            +  T A    +  S  ++ +  L   T  P S  P+ SS         V +       T+
Sbjct: 2377 SSPTTADDTSMPTSTYSEGSTPL---TSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTE 2433

Query: 588  SSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNS 647
            +S SP+     S P + P   +TP+ S P+                      S TPV +S
Sbjct: 2434 ASSSPTTAEGTSIPTSPPSEGTTPLASMPV----------------------STTPVVSS 2471

Query: 648  GSSVLGSLFKQPSFPANKGTEDSLMGRTRE-----TGTEKNTSSLELEESLPEQPETGRQ 702
             +  L +     S P    TE S    T E       T    S+L     +   P    +
Sbjct: 2472 EAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPE 2531

Query: 703  EEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGD--RDLESQAGSLV 760
               L   P        +S E      + + S++G   P    + G    R +      L 
Sbjct: 2532 ASTLSTTPVDSNSPVVTSTEIS----SSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLA 2587

Query: 761  ESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEA 820
             S+A           P+  S+P   S                  T   VS S        
Sbjct: 2588 SSEA-----STLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVST 2642

Query: 821  VAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPAS 880
            +  A+      S+ P +     + +   S      SP   +      +TPG       ++
Sbjct: 2643 MPVASSEASTLSTTPVDTRTLVTTSTGTS-----SSPTTAEGSSMPTSTPGER-----ST 2692

Query: 881  PADHLLLPSQEESFSEVPMSEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSD 940
            P  ++L+     S + +  SEAS+   TP+     + +      ++AS            
Sbjct: 2693 PLTNILV-----STTLLANSEASTLSTTPV-----DTSTPVTTSAEASSSPTTAEGTSMR 2742

Query: 941  LQLVSDFKSPIMADLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALS 1000
            +   SD  +P+ + L   + ++P  +S+   +     D          A SS       S
Sbjct: 2743 ISTPSDGSTPLTSIL---VSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTS 2799

Query: 1001 LGLVVPCPERGKGPSGEADRLVLGEGLCDFRLQAP-------QASVTAPSEQTTEFGIHK 1053
            +    P        S   +   +           P         S  A S  TT  GI  
Sbjct: 2800 MPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVV 2859

Query: 1054 P--HLGKSSSLDKQLP---GPSGGEEEKPM----------------GNGSPSPPPGTSLD 1092
            P     + S+L   +P    P    E   +                G+ SP+   GTS+ 
Sbjct: 2860 PISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSM- 2918

Query: 1093 NPVPSPSPSEI-----------FPVTHSFPSSAHS---DTH---HTSTAESQKKATAEGS 1135
               P  +PSE+            PV  S  S+  +   DT     TS   S    TAEG+
Sbjct: 2919 ---PISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGT 2975

Query: 1136 AGRVENFGKRK-PLLQAWVSPSETHPVSA 1163
            +  +   G+R+ PL    VS   T PV++
Sbjct: 2976 SMPISTPGERRTPLTSMSVS---TMPVAS 3001



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 87/422 (20%), Positives = 142/422 (33%), Gaps = 40/422 (9%)

Query: 511  TEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSS 570
            TE  + P +      P S+P    T            + P + +P  T   S+L   P  
Sbjct: 2196 TEARSSPTTSEGTSMPTSTPSEGSTPFT---------SMPVSTMPVVTSEASTLSATPVD 2246

Query: 571  SGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPL 630
            +      S       T+++ SP+     S P +     +TP+ S P+     A SE   L
Sbjct: 2247 TSTPVTTS-------TEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTL 2299

Query: 631  LPKA-------ELQTESLTPVPNS-GSSVLGSLFKQPSFPANKGTEDSLMGRTRETG--- 679
                          TE+ +P P + G+S+  S   + + P  +    + M  + ET    
Sbjct: 2300 STTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLS 2359

Query: 680  -TEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAV 738
             T  +TS+     S      T   +  +P     +     +S     +P   S +S  + 
Sbjct: 2360 TTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHST 2419

Query: 739  SPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMGLNL 798
            +PV            S + +  E  +   +       P+ AS+P   + +   E   L+ 
Sbjct: 2420 TPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPL-ASMPVSTTPVVSSEAGTLST 2478

Query: 799  RKDQKKTKKRVS---FSEQLFTEEAVAGAALLVEGH---SSCPQELNPAWSVAGNASDGE 852
                  T    S    S     E+ V   +   EG    +S P    P  S   +     
Sbjct: 2479 TPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTT 2538

Query: 853  PPE--SPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPM--SEASSAKDT 908
            P +  SP    +E  S  T    T   P S       P +    S  P+  SEAS+   T
Sbjct: 2539 PVDSNSPVVTSTEISSSATSAEGT-SMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTT 2597

Query: 909  PL 910
            P+
Sbjct: 2598 PV 2599



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 67/329 (20%), Positives = 109/329 (33%), Gaps = 58/329 (17%)

Query: 382  SESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPE----------- 430
            SE ST   L SM L +       +  L       ++ AT   + S  P            
Sbjct: 1981 SEGSTP--LTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTST 2038

Query: 431  -SRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEK 489
             S R++ L+ M     +   SEG    T P   K  +    +    A+     +   +  
Sbjct: 2039 PSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPS 2098

Query: 490  DTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQ 549
            + + +++    S         T P A PE+ +    P+ S  +P   + +      P   
Sbjct: 2099 EGSPLLTSIPLS---------TTPVASPEASTLSTTPVDS-NSPVITSTEVSSSPIPTEG 2148

Query: 550  PTARLPSPTDSPSSLPPLPSSS-----------GQASVPSELGHGADTQSSESPSVFSSL 598
             + +  + +D  + L  +P S+               V +       T++  SP+     
Sbjct: 2149 TSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGT 2208

Query: 599  SSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQ 658
            S P + P   STP  S P+                      S  PV  S +S L +    
Sbjct: 2209 SMPTSTPSEGSTPFTSMPV----------------------STMPVVTSEASTLSATPVD 2246

Query: 659  PSFPANKGTEDSLMGRTRETGTEKNTSSL 687
             S P    TE +    T E GT   TS+L
Sbjct: 2247 TSTPVTTSTEATSSPTTAE-GTSIPTSTL 2274



 Score = 34.3 bits (77), Expect = 0.79
 Identities = 105/541 (19%), Positives = 191/541 (35%), Gaps = 54/541 (9%)

Query: 155  ASMFDLSMKDKSRNPFGKLKDKIKGKNKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKK 214
            ++ F  S    S +P       ++      GS + + ++ S+T    S+  +       +
Sbjct: 3544 SNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDR 3603

Query: 215  SKIKTLLSKSNLQKTPLSQSMSVLPTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMS 274
            S   T  ++SN   TP    +  LP S P +V   P              E+ +AS +  
Sbjct: 3604 STPVTTSTQSN--STPTPPEVITLPMSTPSEVST-PLTIMPVSTTSVTISEAGTASTLPV 3660

Query: 275  HKRTASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGE 334
                 ST +    QV+ +    EG +      S+            G+      P +   
Sbjct: 3661 D---TSTPVITSTQVSSSPVTPEGTTMPIWTPSE------------GSTPLTTMPVSTTR 3705

Query: 335  IKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKE--------PAEGGGLSSDRQLSESST 386
            +  S  S+  +P       + +STE +++ +  +        P E   L +   +S +  
Sbjct: 3706 VTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPV 3765

Query: 387  KDSLKSMT--LPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKK 444
                +S T  +PS   +  ++     + +P   E T     S   E R + L +++    
Sbjct: 3766 TRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSE-RSTLLTTVLISPI 3824

Query: 445  DVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNL 504
             V   SE     T PG     +L   K G   S PAE    R      ++ S + + L  
Sbjct: 3825 SVMSPSEASTLSTPPGDTSTPLLTSTKAGS-FSIPAEVTTIR-----ISITSERSTPLTT 3878

Query: 505  FEDVQITEPEAEPESKSEPRPPI-------------SSPRAPQTRAVKPRLEVSPEAQP- 550
               V  T P + P +     PP+             S+P  P    +   + ++  + P 
Sbjct: 3879 LL-VSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSV-ITEGSTPG 3936

Query: 551  -TARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTS 609
             T  +PS   + S+    P+++G  S P       +T S+ S S  +S S+      +T 
Sbjct: 3937 TTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFST--TKEFTTP 3994

Query: 610  TPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTED 669
                + PL     + +   P        T + T    S      S+  +P  P+++ +  
Sbjct: 3995 AMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRP 4054

Query: 670  S 670
            S
Sbjct: 4055 S 4055



 Score = 30.8 bits (68), Expect = 8.7
 Identities = 40/175 (22%), Positives = 61/175 (34%), Gaps = 28/175 (16%)

Query: 511  TEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSS 570
            TE  + P +      P S+P    T      +  +P     A   S T   +S P   S 
Sbjct: 1725 TEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTS- 1783

Query: 571  SGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPL 630
                           T+++ SP+     S P +      TP+ S P+            L
Sbjct: 1784 ---------------TEATSSPTTAEGTSIPTSTLSEGMTPLTSTPV---------SHTL 1819

Query: 631  LPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTS 685
            +  +E  T S TPV ++   V  +       PA +GT  S+   T   G+   TS
Sbjct: 1820 VANSEASTLSTTPVDSNSPVVTSTAVSSSPTPA-EGT--SIATSTPSEGSTALTS 1871


>gi|209862789 microtubule associated monoxygenase, calponin and LIM
            domain containing 3 isoform 1 [Homo sapiens]
          Length = 2002

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 129/623 (20%), Positives = 222/623 (35%), Gaps = 108/623 (17%)

Query: 202  SDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSV--LPTSKPEKVL-----LRPGDFQ 254
            S  ES ++++ ++ + +  L  S+L   P  +++ +  L   K E+ L       PG+ +
Sbjct: 934  SSSESEMEEEGEEEEEEPRLPPSDLGGVPWKEAVRIHALLKGKSEEELEASKSFGPGNEE 993

Query: 255  SQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSR 314
             + +E++ E+E     D    + ++    ++L QV       E                 
Sbjct: 994  EEEEEEEYEEEEEEDYDE-EEEESSEAGNQRLQQVMHAADPLE----------------- 1035

Query: 315  SNVCINGNHVY-LEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLA--AGSWKEPAE 371
                ++  H+   E+ E      +SS S +P  +   ++ + S    +   A    +P +
Sbjct: 1036 IQADVHWTHIREREEEERMAPASESSASGAPLDENDLEEDVDSEPAEIEGEAAEDGDPGD 1095

Query: 372  GGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPES 431
             G    D Q    S  D+ + + LP                 PA  EA  E + S+  E 
Sbjct: 1096 TGAELDDDQHWSDSPSDADRELRLP----------------CPAEGEAELELRVSEDEEK 1139

Query: 432  RRSSLLSLMTGKKDVAKG-SEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKD 490
                   L    K   +G S+  +P+  P  ++  +L          GP    V      
Sbjct: 1140 -------LPASPKHQERGPSQATSPIRSP--QESALLFIPVHSPSTEGPQLPPV------ 1184

Query: 491  TAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRP---PISSPRAPQTRAVKPRLEVSPE 547
              A    +     LF +  + + + + ++ S+ +    PI S       A  P    SP+
Sbjct: 1185 -PAATQEKSPEERLFPEPLLPKEKPKADAPSDLKAVHSPIRSQPVTLPEARTPVSPGSPQ 1243

Query: 548  AQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPIS 607
             QP     +P  SP  +   P  S +A+VPS          ++SP  F        AP  
Sbjct: 1244 PQPPVAASTPPPSPLPICSQPQPSTEATVPS---------PTQSPIRFQ------PAPAK 1288

Query: 608  TSTPIESWPLVDRGQAKSE-GPPL-----LPKAELQTE------------SLTPVPNSGS 649
            TSTP+   P+  +   K   G PL     L +++L  E             LTPV  S  
Sbjct: 1289 TSTPLAPLPVQSQSDTKDRLGSPLAVDEALRRSDLVEEFWMKSAEIRRSLGLTPVDRSKG 1348

Query: 650  SVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRF 709
                    +PSFP       SL   + E   +     L    S+P++    + E E    
Sbjct: 1349 -------PEPSFPTPAFRPVSLKSYSVEKSPQDEGLHLLKPLSIPKRLGLPKPEGEPLSL 1401

Query: 710  PCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAE 769
            P  +         AQE    LS SS   +      ++   + L SQ+ +  +S       
Sbjct: 1402 PTPRSPSDRELRSAQEERRELSSSSGLGLHG----SSSNMKTLGSQSFNTSDSAMLTPPS 1457

Query: 770  EVAPPLPMGASVPSIDSMMRKLE 792
               PP P G    ++   +R+ E
Sbjct: 1458 SPPPPPPPGEEPATLRRKLREAE 1480



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 85/424 (20%), Positives = 137/424 (32%), Gaps = 88/424 (20%)

Query: 677  ETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDG 736
            +TG E++ +S   E  + E+   G +EEE PR P       P   EA  +   L   S+ 
Sbjct: 924  DTGAEEDVASSSSESEMEEE---GEEEEEEPRLPPSDLGGVPWK-EAVRIHALLKGKSEE 979

Query: 737  AVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMGL 796
             +        G + + E +     E +  D  EE       G     +  +M   + + +
Sbjct: 980  ELEASKSFGPGNEEE-EEEEEEYEEEEEEDYDEEEEESSEAGNQ--RLQQVMHAADPLEI 1036

Query: 797  NLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPES 856
                     ++R          E+ A  A L E       +  PA      A DG+P ++
Sbjct: 1037 QADVHWTHIREREEEERMAPASESSASGAPLDENDLEEDVDSEPAEIEGEAAEDGDPGDT 1096

Query: 857  PHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLFRMEGE 916
                D ++    +P      + A     L  P++ E+  E+ +SE               
Sbjct: 1097 GAELDDDQHWSDSP------SDADRELRLPCPAEGEAELELRVSE--------------- 1135

Query: 917  DALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDERIDQVE 976
                        D E L + P    +  S   SPI +    +L  IP        +    
Sbjct: 1136 ------------DEEKLPASPKHQERGPSQATSPIRSPQESALLFIP--------VHSPS 1175

Query: 977  DDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFRLQAPQ 1036
             +G Q+                      VP   + K P    +  +  E L    L   +
Sbjct: 1176 TEGPQLPP--------------------VPAATQEKSP----EERLFPEPL----LPKEK 1207

Query: 1037 ASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDNPVP 1096
                APS+      +H P   +  +L          E   P+  GSP P P  +   P P
Sbjct: 1208 PKADAPSDLKA---VHSPIRSQPVTLP---------EARTPVSPGSPQPQPPVAASTPPP 1255

Query: 1097 SPSP 1100
            SP P
Sbjct: 1256 SPLP 1259


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 108/571 (18%), Positives = 196/571 (34%), Gaps = 52/571 (9%)

Query: 158 FDLSMKDKSRNPFGKLKDKIKGKNKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKI 217
           F   +KD  +N   K          ++GS   +     TTP   +   + V    K +  
Sbjct: 62  FCAEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA 121

Query: 218 KTLLSKSNLQKTPLSQSMSVLPTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKR 277
           K +  + +L     +   + L  +K   V  +     ++    D +++++SA +  S ++
Sbjct: 122 KPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 181

Query: 278 TASTDLKQLNQV-NFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIK 336
           T++ DL   ++V     PK E         +K   L+                      K
Sbjct: 182 TSAKDLAPTSKVLAKPTPKAE-------TTTKGPALTTP--------------------K 214

Query: 337 DSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLP 396
           + +P++   P     K    +T   A  + KEPA     S+     E +   + +     
Sbjct: 215 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 274

Query: 397 SYRPAPLVSGDLRENMAPANSEATKEAKES--KKPESRRSSLLSLMTGKKDVAKGSEGEN 454
              PAP  + +       +     KE   +  KKP        +  T K+      +   
Sbjct: 275 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 334

Query: 455 PLT---VPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQIT 511
           P T    P   KE       P + A    ++    + K+ A   +++ S     E    T
Sbjct: 335 PTTKEPAPTTPKEP--APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 392

Query: 512 EPEAEPESKSEPRPPI-----SSPRAPQTRAVKPRLEVSPE--AQPTARLPSPTDSPSSL 564
              A P +  EP P       ++P+ P     K     +P+  A  T + P+PT      
Sbjct: 393 TKSA-PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 451

Query: 565 P-----PLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVD 619
           P     P P+++ + +  +       T    +P+    L+      ++ +TP +  P   
Sbjct: 452 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 511

Query: 620 RGQAKS---EGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTR 676
              A +   E  P  P+    T      PN+      +  K+P+    K    +    T 
Sbjct: 512 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 571

Query: 677 ETGTEKNTSSLELEESLPEQPETGRQEEELP 707
            T T K T+   L+E  P  P+    +E  P
Sbjct: 572 PT-TPKGTAPTTLKEPAPTTPKKPAPKELAP 601



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 85/397 (21%), Positives = 132/397 (33%), Gaps = 52/397 (13%)

Query: 326 LEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESS 385
           +E+  AK     S   + P+PK        ++T+  A  + KEP             +  
Sbjct: 179 IEKTSAKDLAPTSKVLAKPTPKAE------TTTKGPALTTPKEPTPTTPKEPASTTPKEP 232

Query: 386 TKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKD 445
           T  ++KS       PAP  +              TKE   +   E          T  K+
Sbjct: 233 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP-------TTTKE 285

Query: 446 VAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLF 505
            A  +    P T              P E A    +     + K+ A    ++ +     
Sbjct: 286 PAPTTTKSAPTT--------------PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK 331

Query: 506 EDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPE--AQPTARLPSPTDSPSS 563
           E    T+ E  P +  EP P  ++P+ P     K     +P+  A  T + PSPT     
Sbjct: 332 EPAPTTK-EPAPTTPKEPAP--TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT----- 383

Query: 564 LPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQA 623
            P  P+ +   S P+     A T +  +P+     S       + +TP E  P   +  A
Sbjct: 384 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 443

Query: 624 KSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEK- 682
                P  PK    T    P P +      +  K+P+    K T  +   +   T  EK 
Sbjct: 444 -----PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 498

Query: 683 ---------NTSSLELEESLPEQPETGRQEEELPRFP 710
                     T+  EL  + PE+P     EE  P  P
Sbjct: 499 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 535



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 78/385 (20%), Positives = 131/385 (34%), Gaps = 39/385 (10%)

Query: 336 KDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTL 395
           K+ +P+++  P     K    +T   A  + KEPA     S+     E S   + +    
Sbjct: 370 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 429

Query: 396 PSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENP 455
               PAP           PA +   + A  + K  +  ++     T  K+ A  +  E  
Sbjct: 430 TPKEPAPTTP------KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 483

Query: 456 LTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEA 515
            T P +     L    P + A    E     + ++ A     + +     E    T   A
Sbjct: 484 PTTPKK-----LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 538

Query: 516 EPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQAS 575
            P +  EP P  ++P+ P              A  T + P+PT    + P  P    + +
Sbjct: 539 APNTPKEPAP--TTPKEP--------------APTTPKEPAPTTPKETAPTTP----KGT 578

Query: 576 VPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAE 635
            P+ L   A T + + P+      +    P ST T  +  P   +G A     P  PK  
Sbjct: 579 APTTLKEPAPT-TPKKPAPKELAPTTTKEPTST-TCDKPAPTTPKGTA-----PTTPKEP 631

Query: 636 LQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPE 695
             T    P P +      +  K+P+    K      +  T   G    TS  +   + P+
Sbjct: 632 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPK 690

Query: 696 QPETGRQEEELPRFPCKKQDYSPSS 720
           +      +E  P  P K    +P +
Sbjct: 691 ETAPTTPKEPAPTTPKKPAPTTPET 715



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 72/357 (20%), Positives = 118/357 (33%), Gaps = 27/357 (7%)

Query: 376 SSDRQLSESSTKDSLKSMTLPSYRPA-PLVSGDLRENMAPANSEATKEAKES-------- 426
           +S  Q ++ ST   + +    + RP+ P  S   +E     N E T E KE+        
Sbjct: 104 TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 163

Query: 427 ----KKPESRRSSLLSLMTGKKDVAKGSEG-ENPLTVPGREKEGMLMGVKPGEDASGPAE 481
               +K  S + +     T  KD+A  S+    P        +G  +        + P E
Sbjct: 164 TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE 223

Query: 482 DLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPR 541
                 ++ T   +    S+    ++   T  ++ P +  EP P  +   AP T   +P 
Sbjct: 224 PASTTPKEPTPTTIK---SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK-EPA 279

Query: 542 LEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSP 601
              + E  PT    +PT      P  P        P+     A T   E         +P
Sbjct: 280 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA----PTTPKEPAPTTPKEPTPTTPKEPAP 335

Query: 602 IAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSF 661
                + +TP E  P   +  A     P  PK    T    P P +      +  K+P+ 
Sbjct: 336 TTKEPAPTTPKEPAPTAPKKPA-----PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 390

Query: 662 PANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSP 718
              K    +       T     T+  E   +  ++P     +E  P  P K    +P
Sbjct: 391 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 447



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 49/253 (19%), Positives = 87/253 (34%), Gaps = 23/253 (9%)

Query: 489 KDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP--RLEVSP 546
           K+ A   ++  +S    +    T  E  P +  EP P      AP T    P    EVS 
Sbjct: 666 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 725

Query: 547 EA---QPTARLPSPTDSPSSLPPLPSSSGQASVPSELG-HGADTQSSESPSVFSSLSSPI 602
                +PT    SP +S   L   P+     + P E G     T ++  P + ++     
Sbjct: 726 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 785

Query: 603 AAPISTSTP--IESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGS-----SVLGSL 655
                 +TP    + P + +  A +       K    T  +T      +     + L + 
Sbjct: 786 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 845

Query: 656 FKQPSFPANKGT----------EDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEE 705
              P     K T          E++   + R T ++  T   +     P++P + ++ + 
Sbjct: 846 TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT 905

Query: 706 LPRFPCKKQDYSP 718
           +PR    K   +P
Sbjct: 906 MPRVRKPKTTPTP 918



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 15/93 (16%)

Query: 1059 SSSLDKQLP------GPSGGEEEKPMGNGSPSP--PPGTS---LDNPVPS----PSPSEI 1103
            S++ DK  P       P+  +E  P     P+P  P GT+   L  P P+    P+P E+
Sbjct: 609  STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 668

Query: 1104 FPVTHSFPSSAHSDTHHTSTAESQKKATAEGSA 1136
             P T   P+S  SD    +T +     T +  A
Sbjct: 669  APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 701


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 108/571 (18%), Positives = 196/571 (34%), Gaps = 52/571 (9%)

Query: 158 FDLSMKDKSRNPFGKLKDKIKGKNKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKI 217
           F   +KD  +N   K          ++GS   +     TTP   +   + V    K +  
Sbjct: 103 FCAEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA 162

Query: 218 KTLLSKSNLQKTPLSQSMSVLPTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKR 277
           K +  + +L     +   + L  +K   V  +     ++    D +++++SA +  S ++
Sbjct: 163 KPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 222

Query: 278 TASTDLKQLNQV-NFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIK 336
           T++ DL   ++V     PK E         +K   L+                      K
Sbjct: 223 TSAKDLAPTSKVLAKPTPKAE-------TTTKGPALTTP--------------------K 255

Query: 337 DSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLP 396
           + +P++   P     K    +T   A  + KEPA     S+     E +   + +     
Sbjct: 256 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 315

Query: 397 SYRPAPLVSGDLRENMAPANSEATKEAKES--KKPESRRSSLLSLMTGKKDVAKGSEGEN 454
              PAP  + +       +     KE   +  KKP        +  T K+      +   
Sbjct: 316 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 375

Query: 455 PLT---VPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQIT 511
           P T    P   KE       P + A    ++    + K+ A   +++ S     E    T
Sbjct: 376 PTTKEPAPTTPKEP--APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 433

Query: 512 EPEAEPESKSEPRPPI-----SSPRAPQTRAVKPRLEVSPE--AQPTARLPSPTDSPSSL 564
              A P +  EP P       ++P+ P     K     +P+  A  T + P+PT      
Sbjct: 434 TKSA-PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 492

Query: 565 P-----PLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVD 619
           P     P P+++ + +  +       T    +P+    L+      ++ +TP +  P   
Sbjct: 493 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 552

Query: 620 RGQAKS---EGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTR 676
              A +   E  P  P+    T      PN+      +  K+P+    K    +    T 
Sbjct: 553 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 612

Query: 677 ETGTEKNTSSLELEESLPEQPETGRQEEELP 707
            T T K T+   L+E  P  P+    +E  P
Sbjct: 613 PT-TPKGTAPTTLKEPAPTTPKKPAPKELAP 642



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 85/397 (21%), Positives = 132/397 (33%), Gaps = 52/397 (13%)

Query: 326 LEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESS 385
           +E+  AK     S   + P+PK        ++T+  A  + KEP             +  
Sbjct: 220 IEKTSAKDLAPTSKVLAKPTPKAE------TTTKGPALTTPKEPTPTTPKEPASTTPKEP 273

Query: 386 TKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKD 445
           T  ++KS       PAP  +              TKE   +   E          T  K+
Sbjct: 274 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP-------TTTKE 326

Query: 446 VAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLF 505
            A  +    P T              P E A    +     + K+ A    ++ +     
Sbjct: 327 PAPTTTKSAPTT--------------PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK 372

Query: 506 EDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPE--AQPTARLPSPTDSPSS 563
           E    T+ E  P +  EP P  ++P+ P     K     +P+  A  T + PSPT     
Sbjct: 373 EPAPTTK-EPAPTTPKEPAP--TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT----- 424

Query: 564 LPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQA 623
            P  P+ +   S P+     A T +  +P+     S       + +TP E  P   +  A
Sbjct: 425 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 484

Query: 624 KSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEK- 682
                P  PK    T    P P +      +  K+P+    K T  +   +   T  EK 
Sbjct: 485 -----PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 539

Query: 683 ---------NTSSLELEESLPEQPETGRQEEELPRFP 710
                     T+  EL  + PE+P     EE  P  P
Sbjct: 540 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 576



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 78/385 (20%), Positives = 131/385 (34%), Gaps = 39/385 (10%)

Query: 336 KDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTL 395
           K+ +P+++  P     K    +T   A  + KEPA     S+     E S   + +    
Sbjct: 411 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 470

Query: 396 PSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENP 455
               PAP           PA +   + A  + K  +  ++     T  K+ A  +  E  
Sbjct: 471 TPKEPAPTTP------KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 524

Query: 456 LTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEA 515
            T P +     L    P + A    E     + ++ A     + +     E    T   A
Sbjct: 525 PTTPKK-----LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 579

Query: 516 EPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQAS 575
            P +  EP P  ++P+ P              A  T + P+PT    + P  P    + +
Sbjct: 580 APNTPKEPAP--TTPKEP--------------APTTPKEPAPTTPKETAPTTP----KGT 619

Query: 576 VPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAE 635
            P+ L   A T + + P+      +    P ST T  +  P   +G A     P  PK  
Sbjct: 620 APTTLKEPAPT-TPKKPAPKELAPTTTKEPTST-TCDKPAPTTPKGTA-----PTTPKEP 672

Query: 636 LQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPE 695
             T    P P +      +  K+P+    K      +  T   G    TS  +   + P+
Sbjct: 673 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPK 731

Query: 696 QPETGRQEEELPRFPCKKQDYSPSS 720
           +      +E  P  P K    +P +
Sbjct: 732 ETAPTTPKEPAPTTPKKPAPTTPET 756



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 72/357 (20%), Positives = 118/357 (33%), Gaps = 27/357 (7%)

Query: 376 SSDRQLSESSTKDSLKSMTLPSYRPA-PLVSGDLRENMAPANSEATKEAKES-------- 426
           +S  Q ++ ST   + +    + RP+ P  S   +E     N E T E KE+        
Sbjct: 145 TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 204

Query: 427 ----KKPESRRSSLLSLMTGKKDVAKGSEG-ENPLTVPGREKEGMLMGVKPGEDASGPAE 481
               +K  S + +     T  KD+A  S+    P        +G  +        + P E
Sbjct: 205 TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE 264

Query: 482 DLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPR 541
                 ++ T   +    S+    ++   T  ++ P +  EP P  +   AP T   +P 
Sbjct: 265 PASTTPKEPTPTTIK---SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK-EPA 320

Query: 542 LEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSP 601
              + E  PT    +PT      P  P        P+     A T   E         +P
Sbjct: 321 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA----PTTPKEPAPTTPKEPTPTTPKEPAP 376

Query: 602 IAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSF 661
                + +TP E  P   +  A     P  PK    T    P P +      +  K+P+ 
Sbjct: 377 TTKEPAPTTPKEPAPTAPKKPA-----PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 431

Query: 662 PANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSP 718
              K    +       T     T+  E   +  ++P     +E  P  P K    +P
Sbjct: 432 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 488



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 49/253 (19%), Positives = 87/253 (34%), Gaps = 23/253 (9%)

Query: 489 KDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP--RLEVSP 546
           K+ A   ++  +S    +    T  E  P +  EP P      AP T    P    EVS 
Sbjct: 707 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 766

Query: 547 EA---QPTARLPSPTDSPSSLPPLPSSSGQASVPSELG-HGADTQSSESPSVFSSLSSPI 602
                +PT    SP +S   L   P+     + P E G     T ++  P + ++     
Sbjct: 767 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 826

Query: 603 AAPISTSTP--IESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGS-----SVLGSL 655
                 +TP    + P + +  A +       K    T  +T      +     + L + 
Sbjct: 827 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 886

Query: 656 FKQPSFPANKGT----------EDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEE 705
              P     K T          E++   + R T ++  T   +     P++P + ++ + 
Sbjct: 887 TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT 946

Query: 706 LPRFPCKKQDYSP 718
           +PR    K   +P
Sbjct: 947 MPRVRKPKTTPTP 959



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 15/93 (16%)

Query: 1059 SSSLDKQLP------GPSGGEEEKPMGNGSPSP--PPGTS---LDNPVPS----PSPSEI 1103
            S++ DK  P       P+  +E  P     P+P  P GT+   L  P P+    P+P E+
Sbjct: 650  STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 709

Query: 1104 FPVTHSFPSSAHSDTHHTSTAESQKKATAEGSA 1136
             P T   P+S  SD    +T +     T +  A
Sbjct: 710  APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 742


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 84/302 (27%), Positives = 117/302 (38%), Gaps = 45/302 (14%)

Query: 327 EQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESST 386
           E P+    +++SS S SP+PK  +KK          + S +   +        +    S 
Sbjct: 166 EPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESK 225

Query: 387 KDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDV 446
           K   +S T  S R +         +  PA    ++ A  S   +S  SS  S    +   
Sbjct: 226 KRKHRSPTPKSKRKSKDKKRKRSRSTTPA--PKSRRAHRSTSADSASSSDTSRSRSRSAA 283

Query: 447 AK----GSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSL 502
           AK       G +P    GR  EG     +PG  ++       R S  +TA   ++Q SS 
Sbjct: 284 AKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTST------QRPSSPETA---TKQPSS- 333

Query: 503 NLFED-------VQITEPEAEPE-SKSEPRPPISSP-------RAPQTRAVKPRLE--VS 545
             +ED          T P   PE S + P PP  +P        +PQ  A  P  +  V+
Sbjct: 334 -PYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN 392

Query: 546 P--EAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIA 603
           P  EA PT R  SP  SP  LP   SSS ++S PS         +S SP       SP  
Sbjct: 393 PPSEASPT-RDRSPPKSPEKLP--QSSSSESSPPSPQPTKVSRHASSSP------ESPKP 443

Query: 604 AP 605
           AP
Sbjct: 444 AP 445



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 89/398 (22%), Positives = 139/398 (34%), Gaps = 48/398 (12%)

Query: 533  PQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESP 592
            P T A  P    +P+A  +A L  P  + ++ P   + S  A+    L   + T +  +P
Sbjct: 2317 PPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAA---LAPASLTSARMAP 2373

Query: 593  SVF-SSLSSPIAAPISTSTPIE---SWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNS- 647
            ++  ++L+SP   P+S    +    S PL+DR  A+S  PP  P     T    P P+S 
Sbjct: 2374 ALSGANLTSP-RVPLSAYERVSGRTSPPLLDR--ARSRTPPSAPSQSRMTSERAPSPSSR 2430

Query: 648  -----GSSVLGSLFKQPSFPANKGTEDS----LMGRTRETGTEKNTSSLELEESLPEQPE 698
                   S+L     QP  P      D     +   T   G++  +S      +      
Sbjct: 2431 MGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDH 2490

Query: 699  TGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSL--------SSDGAVSPVGELAAGGDR 750
             G      P  P       P+S  AQ+ P AL+         SS  + S     ++    
Sbjct: 2491 NGMLSVPAPGVPHSDVGEPPASTGAQQ-PSALAALQPAKERRSSSSSSSSSSSSSSSSSS 2549

Query: 751  DLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVS 810
               S +     S +  ++  V P + +   VPS     ++    G        K K+R S
Sbjct: 2550 SSSSSSSGSSSSDSEGSSLPVQPEVAL-KRVPSPTPAPKEAVREGRPPEPTPAKRKRRSS 2608

Query: 811  FSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSERESVTTP 870
             S                   SS     + + S + ++S      S  +  S   S   P
Sbjct: 2609 SSSS--------------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP 2654

Query: 871  GPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDT 908
            GP     PASP      P   E  S  P     S +D+
Sbjct: 2655 GPQALPKPASPKK----PPPGERRSRSPRKPIDSLRDS 2688



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 73/328 (22%), Positives = 122/328 (37%), Gaps = 34/328 (10%)

Query: 513  PEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSS-S 571
            P     + + PR P+S+      R   P L+ +    P +  PS +   S   P PSS  
Sbjct: 2373 PALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPS-APSQSRMTSERAPSPSSRM 2431

Query: 572  GQASVPSELGHGADTQSSESPSVFSSLSSPIAA---PISTSTPIESWPLV-------DRG 621
            GQA   S L    D   S  PS FS  S  + A   P++ S  + S  +        D  
Sbjct: 2432 GQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHN 2491

Query: 622  QAKSEGPPLLPKAELQTESLTPVPNSGS---SVLGSL-----FKQPSFPANKGTEDSLMG 673
               S   P +P +++      P  ++G+   S L +L      +  S  ++  +  S   
Sbjct: 2492 GMLSVPAPGVPHSDVG----EPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSS 2547

Query: 674  RTRETGTEKNTSSLELE-ESLPEQPETGRQEEELPRFPCKKQDY------SPSSGEAQEV 726
             +  + +   +SS + E  SLP QPE   +    P  P  K+         P+  + +  
Sbjct: 2548 SSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT-PAPKEAVREGRPPEPTPAKRKRR 2606

Query: 727  PFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDS 786
              + S SS  + S     ++       S + S   S +  ++   A P P     P+   
Sbjct: 2607 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPK 2666

Query: 787  MMRKLEEMGLNLRK--DQKKTKKRVSFS 812
                 E    + RK  D  +  + +S+S
Sbjct: 2667 KPPPGERRSRSPRKPIDSLRDSRSLSYS 2694



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 74/311 (23%), Positives = 101/311 (32%), Gaps = 44/311 (14%)

Query: 329 PEAKGEIKDS----SPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSES 384
           P++K + KD     S S++P+PK  R+ H  +S ++ +             SSD   S S
Sbjct: 234 PKSKRKSKDKKRKRSRSTTPAPKS-RRAHRSTSADSAS-------------SSDTSRSRS 279

Query: 385 STKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKK 444
            +  +    T  + R     SG   E  AP +   T   +    PE+      S    K 
Sbjct: 280 RSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKD 339

Query: 445 DVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNL 504
              K      P   P R   G      P   A  P             A        +N 
Sbjct: 340 KDKKEKSATRPSPSPERSSTG------PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNP 393

Query: 505 FEDVQITE---PEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSP 561
             +   T    P   PE   +     SSP +PQ   V      SPE+      P P  +P
Sbjct: 394 PSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPES------PKPAPAP 447

Query: 562 SSLPPLPSSSGQASVPSELGHG---ADTQSSESPSVFSSLS-SPIAAPISTSTPIESWPL 617
            S   + SS           HG    D   S +PS     S SP  A    S    S   
Sbjct: 448 GSHREISSS----PTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRS---RSRTP 500

Query: 618 VDRGQAKSEGP 628
             RG ++S  P
Sbjct: 501 TKRGHSRSRSP 511



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 75/324 (23%), Positives = 116/324 (35%), Gaps = 33/324 (10%)

Query: 376  SSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSS 435
            S  R  SE +   S +    PS    P      R  +  A S+ ++       P +   S
Sbjct: 2415 SQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQS 2474

Query: 436  LLS----------------LMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGP 479
            L S                L      V     GE P +  G ++   L  ++P ++    
Sbjct: 2475 LSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPAST-GAQQPSALAALQPAKER--- 2530

Query: 480  AEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEP-RPPISSPRAPQ-TRA 537
                 R S   +++  S   SS +           ++ E  S P +P ++  R P  T A
Sbjct: 2531 -----RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA 2585

Query: 538  VKPRLEVS--PEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVF 595
             K  +     PE  P  R    + S SS     SSS  +S  S     + + SS S S  
Sbjct: 2586 PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645

Query: 596  SSLSSPIAAPISTSTPIESWP-LVDRGQAKSEGP--PLLPKAELQTESLTPVPNSGSSVL 652
            SS  SP A P   + P  + P     G+ +S  P  P+    + ++ S +PV     S  
Sbjct: 2646 SSSPSP-AKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQ 2704

Query: 653  GSLFKQPSFPANKGTEDSLMGRTR 676
             S   Q S  + +G+     G +R
Sbjct: 2705 PSPRDQQSSSSERGSRRGQRGDSR 2728



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 103/476 (21%), Positives = 166/476 (34%), Gaps = 67/476 (14%)

Query: 179  GKNKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVL 238
            G+   SGS     + PS +P   S+ +S   D K K++   L  +S    +P   S S L
Sbjct: 1534 GQRSRSGSSQELDVKPSASPQERSESDS-SPDSKAKTR-TPLRQRSRSGSSPEVDSKSRL 1591

Query: 239  PT------SKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFT 292
                    S PE         ++Q   D + +  + A   +  +  + +  K        
Sbjct: 1592 SPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRG----- 1646

Query: 293  LPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKK 352
             P  EG S      S  +   +S     G+    E P+ K        SS  SP+  RK 
Sbjct: 1647 -PSPEGSS---STESSPEHPPKSRTARRGSRSSPE-PKTKSRTPPRRRSSRSSPELTRKA 1701

Query: 353  HLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENM 412
             L                      S R  S SS+ ++ +S T P +R +P VS       
Sbjct: 1702 RL----------------------SRRSRSASSSPET-RSRTPPRHRRSPSVS------- 1731

Query: 413  APANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKP 472
            +P  +E ++ ++  +   S R+   S   G+    K    +   +   REK         
Sbjct: 1732 SPEPAEKSRSSRRRRSASSPRTKTTS-RRGRSPSPKPRGLQRSRSRSRREK----TRTTR 1786

Query: 473  GEDASGPAEDLVRRSEKD---TAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISS 529
              D SG ++   RR ++    +     R+G S           P  +  S++  R     
Sbjct: 1787 RRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGS-----GYHSRSPARQESSRTSSRRRRGR 1841

Query: 530  PRAPQTRAVKPRLEVSPEAQPTAR---LPSPTDSPSSLPPLPSSSGQASVPSELGHGADT 586
             R P T   + R   SP     +R    P+      S  PL S     S  S +      
Sbjct: 1842 SRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSR---R 1898

Query: 587  QSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLT 642
            +S    SV    S   A+P+S        P V R +++S  P    ++  +T  +T
Sbjct: 1899 RSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVT 1954



 Score = 39.3 bits (90), Expect = 0.024
 Identities = 147/655 (22%), Positives = 224/655 (34%), Gaps = 146/655 (22%)

Query: 313  SRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFR----------KKHLFSSTENLA 362
            SRS   +     +   P+ +G    SS   + S    R          KK   SS  + +
Sbjct: 702  SRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRS 761

Query: 363  AGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKE 422
              S +  A+   LS  R LS SS     KS T P    +       +    P  S ++  
Sbjct: 762  LSSPRSKAKSR-LSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSS 820

Query: 423  A--KESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPA 480
               K+  K  SR+S   S    K  V  G+          +  E  +   +     S P 
Sbjct: 821  PPPKQKSKTPSRQSHSSSSPHPK--VKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPD 878

Query: 481  EDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRA--- 537
             +L  R    T +  S  GSS    +    T P   P   S P+P + +  +P+ R+   
Sbjct: 879  PELKSR----TPSRHSCSGSSPPRVKSS--TPPRQSPSRSSSPQPKVKAIISPRQRSHSG 932

Query: 538  ------------VKPR--LEVSPEAQPTAR-LPSPTDSPSS---------LPPLPSSSGQ 573
                          PR    VSP +   +R LP  + S SS          PP  S SG 
Sbjct: 933  SSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGS 992

Query: 574  AS----VPSELGHGADTQSSESP--------SVFSSL--SSPIAAPISTSTP-------I 612
             S    V ++   G     S+SP        S+  S   S  + A + +STP       +
Sbjct: 993  ISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGV 1052

Query: 613  ESWPLVDRG----------------QAKSEGPPLLPKAELQTE----------------- 639
             S  L  +                 Q+ SE P L  K++   +                 
Sbjct: 1053 SSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRS 1112

Query: 640  ---------SLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTR-ETGTEKNTSSLEL 689
                     S +P+  SG S   S F+  S        +SL+G++R ET   K   +L  
Sbjct: 1113 PIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPP 1172

Query: 690  EESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGD 749
            +E     P   RQ+++   FP             Q+ P +  +  D   +P  E      
Sbjct: 1173 QEDATASPP--RQKDKFSPFP------------VQDRPESSLVFKDTLRTPPRE------ 1212

Query: 750  RDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMG---LNLRKDQKKTK 806
                S AGS  E+K +++A      LP  +    +  ++ K EE     L+    + K  
Sbjct: 1213 ---RSGAGSSPETKEQNSA------LPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEM 1263

Query: 807  KRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPESPHAED 861
               +F      EE  A +  L +  S    E     S+A  +S G P  SP  ++
Sbjct: 1264 STSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMA--SSWGGPHFSPEHKE 1316



 Score = 39.3 bits (90), Expect = 0.024
 Identities = 56/248 (22%), Positives = 83/248 (33%), Gaps = 41/248 (16%)

Query: 327  EQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESST 386
            +QP A   ++ +    S S          SS+ + ++ S    +  G  SSD + S    
Sbjct: 2516 QQPSALAALQPAKERRSSSSSSSS-----SSSSSSSSSSSSSSSSSGSSSSDSEGSSLPV 2570

Query: 387  KDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDV 446
            +  +    +PS  PAP  +  +RE   P  + A ++ + S    S  SS  S  +     
Sbjct: 2571 QPEVALKRVPSPTPAPKEA--VREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSS 2628

Query: 447  AKGSEGENPLTVPGREKEGMLMGVKPGEDA-SGPAEDLVRRSEKDTAAVVSRQGSSLNLF 505
            +  S   +  +             KPG  A   PA                         
Sbjct: 2629 SSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPK---------------------- 2666

Query: 506  EDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLP 565
                   P  E  S+S PR PI S R  ++ +  P     P  Q     PSP D  SS  
Sbjct: 2667 -----KPPPGERRSRS-PRKPIDSLRDSRSLSYSPVERRRPSPQ-----PSPRDQQSSSS 2715

Query: 566  PLPSSSGQ 573
               S  GQ
Sbjct: 2716 ERGSRRGQ 2723



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 139/651 (21%), Positives = 225/651 (34%), Gaps = 100/651 (15%)

Query: 170  FGKLKDKIKGKNK---DSGSDTASAIIP---STTPSVDSDDESVVKDKKKKSK--IKTLL 221
            FG    ++KG+++   D  SDT+S  +    S +PS+ S  ++  K  + +S   +  L 
Sbjct: 1050 FGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELA 1109

Query: 222  SKSNLQKTPLSQSMSVLPTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTAST 281
            S+S     P+ Q       S   K  + P   QS++  D +   +  ++ ++   R  + 
Sbjct: 1110 SRS-----PIRQDRGEFSASPMLKSGMSPE--QSRFQSDSSSYPTVDSNSLLGQSRLETA 1162

Query: 282  DLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKD---- 337
            + K+       LP +E  +       + D  S   V         ++PE+    KD    
Sbjct: 1163 ESKE----KMALPPQEDAT--ASPPRQKDKFSPFPV--------QDRPESSLVFKDTLRT 1208

Query: 338  -----SSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKS 392
                 S   SSP  K        SS +       ++  E  G       SE     +   
Sbjct: 1209 PPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNF 1268

Query: 393  MTLPSYRPAPLVSGDLRENMAPANSEATK---------------EAKESKKPESRRSSLL 437
             + P     P VS  L ++ + A+ EA +               E KE      R +S  
Sbjct: 1269 ESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFG 1328

Query: 438  SLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDT------ 491
            S +  +     G+E     +   +E    L G    +  + P+ D+  +S + +      
Sbjct: 1329 SPLEFRNSGPLGTEMNTGFSSEVKED---LNGPFLNQLETDPSLDMKEQSTRSSGHSSSE 1385

Query: 492  --------AAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLE 543
                    A + S Q  S  + + V  T       S S P      PR P  R+      
Sbjct: 1386 LSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRS------ 1439

Query: 544  VSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHG-ADTQSSESPSVFSSLSSPI 602
                + P  R  S T S  SL    SS G   +P     G ++  SS  P        P 
Sbjct: 1440 -RSGSSPGLRDGSGTPSRHSLS--GSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPR 1496

Query: 603  AAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPV---PNSGSSVLGSLFKQP 659
            +   S+           R ++ SE        + +T + TP+     SGSS    + K  
Sbjct: 1497 SRSPSSPELNNKCLTPQRERSGSES-----SVDQKTVARTPLGQRSRSGSSQELDV-KPS 1550

Query: 660  SFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPS 719
            + P  +   DS      +T T      L         PE   +    PR     +  S S
Sbjct: 1551 ASPQERSESDSSPDSKAKTRT-----PLRQRSRSGSSPEVDSKSRLSPR-----RSRSGS 1600

Query: 720  SGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEE 770
            S E ++ P A   +  G+ S   E  A   R L  ++ S   SK R  + E
Sbjct: 1601 SPEVKDKPRAAPRAQSGSDSS-PEPKAPAPRALPRRSRSGSSSKGRGPSPE 1650



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 111/499 (22%), Positives = 171/499 (34%), Gaps = 94/499 (18%)

Query: 687  LELEESLPEQPETGRQ-EEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELA 745
            LELEE + EQ    +Q +E++  F     +   + G  +E P         AV+   +LA
Sbjct: 71   LELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETP-----GQRPAVTETHQLA 125

Query: 746  AGGDRDLESQ------AGSLVESKARDA---AEEVAPPLPMGASVPSIDSMMRKLEEMGL 796
               ++  E        + S V+  + D    A E   P P     P   S++R+      
Sbjct: 126  ELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAP---EPPKPYSLVRESSSSRS 182

Query: 797  NLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPES 856
               K +KK KK+               ++   E   S  ++ + + S +       P  +
Sbjct: 183  PTPKQKKKKKKKDRGRRS-------ESSSPRRERKKSSKKKKHRSESESKKRKHRSP--T 233

Query: 857  PHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLFRMEGE 916
            P ++   ++       +T  AP S   H    +   S S+   S + SA           
Sbjct: 234  PKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAA-----AKTHT 288

Query: 917  DALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDERIDQVE 976
             AL  +  S AS   G    P S+    S  +           PS PE A+        +
Sbjct: 289  TALAGRSPSPASGRRGEGDAPFSEPGTTSTQR-----------PSSPETATKQPSSPYED 337

Query: 977  DDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGK-GPSGEADRLVLGEGLCDFRLQAP 1035
             D D+ E      KS+T            P PER   GP   A   +L E        +P
Sbjct: 338  KDKDKKE------KSATRPS---------PSPERSSTGPEPPAPTPLLAER----HGGSP 378

Query: 1036 QASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDNPV 1095
            Q   T P  Q        P    S + D+    P    E+ P  + S S PP        
Sbjct: 379  QPLATTPLSQEPV----NPPSEASPTRDRS---PPKSPEKLPQSSSSESSPP-------- 423

Query: 1096 PSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVEN--FGKRKPLLQAWV 1153
             SP P+++               H +S+ ES K A A GS   + +    K +   +A  
Sbjct: 424  -SPQPTKV-------------SRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKR 469

Query: 1154 SPSETHPVSAQPGAGTGSA 1172
              S +H  S + G     A
Sbjct: 470  DKSHSHTPSRRMGRSRSPA 488



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 62/282 (21%), Positives = 95/282 (33%), Gaps = 28/282 (9%)

Query: 337  DSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLP 396
            DSSP     P+  R +    S+  L         E  G       SESS      + T  
Sbjct: 1481 DSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSG-------SESSVDQKTVARTPL 1533

Query: 397  SYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPL 456
              R     SG  +E     ++   + ++    P+S+  +   L    +  +         
Sbjct: 1534 GQRSR---SGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR 1590

Query: 457  TVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVV------SRQGSSLNLFEDVQI 510
              P R + G    VK    A+  A+     S +  A         SR GSS       + 
Sbjct: 1591 LSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSS----SKGRG 1646

Query: 511  TEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSS 570
              PE    ++S P  P      P++R  +     SPE +  +R P    S  S P L   
Sbjct: 1647 PSPEGSSSTESSPEHP------PKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRK 1700

Query: 571  SGQASVPSELGHGADTQSSESP--SVFSSLSSPIAAPISTST 610
            +  +          +T+S   P      S+SSP  A  S S+
Sbjct: 1701 ARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSS 1742


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 125/598 (20%), Positives = 215/598 (35%), Gaps = 104/598 (17%)

Query: 328  QPEAKGEIKDSSP----SSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSE 383
            QP+     KD++P    S +P PK         +     +   K+P E   LS      E
Sbjct: 678  QPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKE 737

Query: 384  SSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGK 443
             S         +   +P          ++  ++S  TK    S K +S+     +    K
Sbjct: 738  PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL-K 796

Query: 444  KDVAKGSEGENPL--TVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSS 501
             D AK S+   P    V   + + +       +  S P      + +K    V  ++   
Sbjct: 797  TDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK 856

Query: 502  LNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTAR-----LPS 556
                +     +P+A+P  K  P PP   P A QT    P  + SP+ Q  +R     L S
Sbjct: 857  KA--QTKMSPKPDAKPMPKGSPTPPGPRPTAGQT---VPTPQQSPKPQEQSRRFSLNLGS 911

Query: 557  PTDSPSSLPPLP-----------------------SSSGQASVPSELGHGADTQSSESPS 593
             TD+P S P  P                       S++GQ    S+ G GA  + + +PS
Sbjct: 912  ITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPS 971

Query: 594  VFSSLSSPIAAPIST---------STPIE---SWPLVDRGQAKSEGPPLLPKAELQ---- 637
               +   P   P ST         S P++     P  ++ + K+E  P + + E +    
Sbjct: 972  QPPTSQGP---PKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPP 1028

Query: 638  ----TESLTPVPNSGSSVLGSLFKQPSFP----------ANKGTEDSLMGRT-------- 675
                ++SLT  P    +VL +  ++   P           N G++D     T        
Sbjct: 1029 PIKDSKSLTAEPQ--KAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQV 1086

Query: 676  -RETGTEKNTSSLELEESLPEQPETGR----QEEELPRFPCKKQDYSPSSGEAQEVPFAL 730
                G        E++E L    +T R    Q  ++ + P      +PS  +A  +P   
Sbjct: 1087 CNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP-----PAPSGPKASPMPVPT 1141

Query: 731  SLSSD-GAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMR 789
              SS   AV P  +L    +++++++A  ++  K ++       P  +       +S + 
Sbjct: 1142 ESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLE 1201

Query: 790  KLEEMGLNLRKDQKKTKKRVSFSEQLFTEE----------AVAGAALLVEGHSSCPQE 837
            K +   L  +K   + KK +   E++ +EE                LL E  +S P+E
Sbjct: 1202 KDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEE 1259



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 42/136 (30%), Positives = 56/136 (41%), Gaps = 6/136 (4%)

Query: 1031 RLQAPQASVTAPSEQTTEFGIHKP--HLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPG 1088
            ++ A QA     S Q T  G  KP   L   +    Q PGP+    ++P     PS  PG
Sbjct: 448  KIPAQQAGPGKTSAQQT--GPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505

Query: 1089 TSLDNPV-PSPS-PSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRK 1146
            ++   P  P P+ PS   P +   PS        ++   S  K +A+ S   V   G  K
Sbjct: 506  STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK 565

Query: 1147 PLLQAWVSPSETHPVS 1162
            PL    VSPS   P S
Sbjct: 566  PLQPPTVSPSAKQPPS 581



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 94/419 (22%), Positives = 153/419 (36%), Gaps = 71/419 (16%)

Query: 171  GKLKDKIKGKNKDSGSDTASAIIPSTTPSVDSDDESVVK-DKKKKSKIKTLLSKSNLQKT 229
            G+L D  K     SG   +   +P+ + S  +     VK  KK++ ++KT   K  L+K 
Sbjct: 1117 GQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKV 1176

Query: 230  PLSQSMSVLPTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQV 289
              + SM  +P                    D  ++ES    D    K +A  + K L + 
Sbjct: 1177 KETLSMEKIP---------------PMVTTDQKQEESKLEKD----KASALQEKKPLPEE 1217

Query: 290  NFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGF 349
               +P++E       +RS+                 LE+ +   E K   P +  S    
Sbjct: 1218 KKLIPEEE------KIRSEE------------KKPLLEEKKPTPEDKKLLPEAKTSAPEE 1259

Query: 350  RKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGD-- 407
            +K  L  S   +A    +E  EG       Q      +   K   LPS  P  L   D  
Sbjct: 1260 QKHDLLKSQVQIA----EEKLEGRVAPKTVQ---EGKQPQTKMEGLPSGTPQSLPKEDDK 1312

Query: 408  ----LRENMAP---ANSEATKEAKESKKPESRRSSLLSLMTGK-----------KDVAKG 449
                ++E   P   A  +  +  KE  + E  +S   S    K            D    
Sbjct: 1313 TTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISS 1372

Query: 450  SEGENPLTVPGREKEGMLMGVKP---GEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFE 506
            S GE P  +P  EK+ +L G+K     +++S  +   + + E    +++  Q S+L   +
Sbjct: 1373 SLGEIPSLIPTDEKD-ILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEK 1431

Query: 507  DVQITEP-EAEPES-KSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSS 563
              + T+P E  PE  K + +    S     T + +   E   E + T +  S  D PSS
Sbjct: 1432 SEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSS 1490



 Score = 38.5 bits (88), Expect = 0.042
 Identities = 98/492 (19%), Positives = 179/492 (36%), Gaps = 49/492 (9%)

Query: 188  TASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPTSKPEKVL 247
            ++S IIP +   VD        ++++K     L + +  ++    Q M + P S P +  
Sbjct: 2031 SSSFIIPESHEIVDLGTMVTSTEEERK----LLDADAAYEELMKRQQMQLTPGSSPTQAP 2086

Query: 248  LRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLN------QVNFTLPKKEGLSF 301
            +     +S  D D   D S ++S +     T ST    L+        +F+  + E    
Sbjct: 2087 IGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYV 2146

Query: 302  LGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDS-SPSSSPSPKGFRKKHLFSSTEN 360
                R   ++++  ++ +     Y E  E+   +  S +PS + S          S    
Sbjct: 2147 TDYTREIQEIIAHESLILT----YSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITT 2202

Query: 361  LAAGS--WKEPAEGGGLSSDRQLSESSTK------DSLKSMTLPSYRPAPLVSGDLRENM 412
            L + +  + EP +      D +   SST       D  + +++   R AP       +++
Sbjct: 2203 LDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHI 2262

Query: 413  APANSEATKEAKES--KKPESRRSSLLS--LMTGKKDVAKGSEGE--NPLTVPGREKEGM 466
              + S+      ES   KPE   +  +S  L+  +KD  K ++ E  N + +   E    
Sbjct: 2263 VISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRD 2322

Query: 467  LMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPP 526
               ++     S  +E +         A+  ++  S   F   +    E          P 
Sbjct: 2323 KKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPS 2382

Query: 527  ISS-PRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGAD 585
            +SS P  P+       L++S +  P    P P   P   PP P                 
Sbjct: 2383 VSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP--------------LP 2428

Query: 586  TQSSESPSVFSSLSSPIAAPISTSTPI--ESWPLVDRGQAKSEGPPLLPKAELQTESLTP 643
              +S  P++       +A+P++T+TP+      L      +S G   LP   + T +  P
Sbjct: 2429 PPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNG---LPVTRICTTAPPP 2485

Query: 644  VPNSGSSVLGSL 655
            VP   SS+   L
Sbjct: 2486 VPPKPSSIPSGL 2497



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 99/441 (22%), Positives = 158/441 (35%), Gaps = 76/441 (17%)

Query: 340 PSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKS-MTLPSY 398
           P+++ SP   RK+ L SS     +G   +P    G  +   LS+S T D+ +S   LP  
Sbjct: 73  PAAAESPSMHRKQELDSSHPPKQSGRPPDP----GRPAQPGLSKSRTTDTFRSEQKLPGR 128

Query: 399 RPAPLVSGDLRENMAPANSEATKEAKESKKP----ESRRSSLLSLMTGKK---DVAKGSE 451
            P+ +    L+E+ +   ++  +E K S  P    E    S +S +  K    D+   SE
Sbjct: 129 SPSTI---SLKESKS--RTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSE 183

Query: 452 GENPLTVPGRE----KEGMLMGV----------KPGEDASGPAEDLVRR--SEKDTAAVV 495
                T   ++    ++G   G+          KP     GP  D +++  + K  ++  
Sbjct: 184 ASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ 243

Query: 496 SRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTR--------AVKPRLEVSPE 547
             +  S        I  P   P++     P       PQT+        +VKP L  SP 
Sbjct: 244 PEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLP-SP- 301

Query: 548 AQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPIS 607
           ++P  + P+P   P+  P    S    + P              P+  S L+ P+A    
Sbjct: 302 SKPPIQQPTPGKPPAQQPGHEKSQPGPAKP--------------PAQPSGLTKPLAQQPG 347

Query: 608 TSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGT 667
           T  P    P+   G  K    PL P      ++ +  P+S      +L + P        
Sbjct: 348 TVKP----PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ 403

Query: 668 EDS-LMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGE---A 723
           +       T++ GT K          L +QP  G Q       P K     P  G+    
Sbjct: 404 QPGPAKPPTQQVGTPK---------PLAQQP--GLQSPAKAPGPTKTPVQQPGPGKIPAQ 452

Query: 724 QEVPFALSLSSDGAVSPVGEL 744
           Q  P   S    G   P  +L
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQL 473



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 86/438 (19%), Positives = 139/438 (31%), Gaps = 55/438 (12%)

Query: 202 SDDESVVKDKKKKSKI--KTLLSKSNLQKTPLSQSMSVLPTSKPEKVLLRPGDFQSQWDE 259
           SD E+  ++  KK K+  K       + K PL Q        KP      PG    Q D 
Sbjct: 180 SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQ-----PPKPIPKQQGPGRDPLQQDG 234

Query: 260 DDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCI 319
                 S     + S        ++   Q   T   K  L      R  +   ++    +
Sbjct: 235 TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQ-----RDASRPQTKQADIV 289

Query: 320 NGNHVYLEQPE-AKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSD 378
            G  V    P  +K  I+  +P   P+ +   +K           G  K PA+  GL+  
Sbjct: 290 RGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKS--------QPGPAKPPAQPSGLTKP 341

Query: 379 RQLSESSTKDSLK--SMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSL 436
                 + K  ++    T P  +P           + PA   A +   E  KP S +   
Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPAQP-----------LGPAKPPAQQTGSE--KPSSEQPGP 388

Query: 437 LSLM----TGKKDVAKGSEGENPLTVPGREKE-GMLMGVKPGEDASGPAEDLVRRSEKDT 491
            +L      GK    +    + P    G  K      G++    A GP +  V++     
Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK 448

Query: 492 AAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAP-------------QTRAV 538
                + G      +    T+P ++    ++P P    P  P             Q  + 
Sbjct: 449 IPA-QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST 507

Query: 539 KPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSL 598
           KP  +    A+P+ + P  T  PS  P     S Q   P++      T+          L
Sbjct: 508 KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567

Query: 599 SSPIAAPISTSTPIESWP 616
             P  +P +   P +  P
Sbjct: 568 QPPTVSPSAKQPPSQGLP 585



 Score = 31.2 bits (69), Expect = 6.7
 Identities = 33/123 (26%), Positives = 48/123 (39%), Gaps = 27/123 (21%)

Query: 1074 EEKPMGNGSPSPP-----PGTSLDNPVPSPSPSE--------IFPVTHSFPSSAHSDTHH 1120
            + KPM  GSP+PP      G ++  P  SP P E        +  +T + P S  +    
Sbjct: 867  DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDA-PKSQPTTPQE 925

Query: 1121 TST-----------AESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPGAGT 1169
            T T           +++    +  G  G     G   P+ QA  +PS+  P S  P   T
Sbjct: 926  TVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA-PAPSQP-PTSQGPPKST 983

Query: 1170 GSA 1172
            G A
Sbjct: 984  GQA 986


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 125/598 (20%), Positives = 215/598 (35%), Gaps = 104/598 (17%)

Query: 328  QPEAKGEIKDSSP----SSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSE 383
            QP+     KD++P    S +P PK         +     +   K+P E   LS      E
Sbjct: 678  QPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKE 737

Query: 384  SSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGK 443
             S         +   +P          ++  ++S  TK    S K +S+     +    K
Sbjct: 738  PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL-K 796

Query: 444  KDVAKGSEGENPL--TVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSS 501
             D AK S+   P    V   + + +       +  S P      + +K    V  ++   
Sbjct: 797  TDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK 856

Query: 502  LNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTAR-----LPS 556
                +     +P+A+P  K  P PP   P A QT    P  + SP+ Q  +R     L S
Sbjct: 857  KA--QTKMSPKPDAKPMPKGSPTPPGPRPTAGQT---VPTPQQSPKPQEQSRRFSLNLGS 911

Query: 557  PTDSPSSLPPLP-----------------------SSSGQASVPSELGHGADTQSSESPS 593
             TD+P S P  P                       S++GQ    S+ G GA  + + +PS
Sbjct: 912  ITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPS 971

Query: 594  VFSSLSSPIAAPIST---------STPIE---SWPLVDRGQAKSEGPPLLPKAELQ---- 637
               +   P   P ST         S P++     P  ++ + K+E  P + + E +    
Sbjct: 972  QPPTSQGP---PKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPP 1028

Query: 638  ----TESLTPVPNSGSSVLGSLFKQPSFP----------ANKGTEDSLMGRT-------- 675
                ++SLT  P    +VL +  ++   P           N G++D     T        
Sbjct: 1029 PIKDSKSLTAEPQ--KAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQV 1086

Query: 676  -RETGTEKNTSSLELEESLPEQPETGR----QEEELPRFPCKKQDYSPSSGEAQEVPFAL 730
                G        E++E L    +T R    Q  ++ + P      +PS  +A  +P   
Sbjct: 1087 CNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP-----PAPSGPKASPMPVPT 1141

Query: 731  SLSSD-GAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMR 789
              SS   AV P  +L    +++++++A  ++  K ++       P  +       +S + 
Sbjct: 1142 ESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLE 1201

Query: 790  KLEEMGLNLRKDQKKTKKRVSFSEQLFTEE----------AVAGAALLVEGHSSCPQE 837
            K +   L  +K   + KK +   E++ +EE                LL E  +S P+E
Sbjct: 1202 KDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEE 1259



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 42/136 (30%), Positives = 56/136 (41%), Gaps = 6/136 (4%)

Query: 1031 RLQAPQASVTAPSEQTTEFGIHKP--HLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPG 1088
            ++ A QA     S Q T  G  KP   L   +    Q PGP+    ++P     PS  PG
Sbjct: 448  KIPAQQAGPGKTSAQQT--GPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505

Query: 1089 TSLDNPV-PSPS-PSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRK 1146
            ++   P  P P+ PS   P +   PS        ++   S  K +A+ S   V   G  K
Sbjct: 506  STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK 565

Query: 1147 PLLQAWVSPSETHPVS 1162
            PL    VSPS   P S
Sbjct: 566  PLQPPTVSPSAKQPPS 581



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 94/419 (22%), Positives = 153/419 (36%), Gaps = 71/419 (16%)

Query: 171  GKLKDKIKGKNKDSGSDTASAIIPSTTPSVDSDDESVVK-DKKKKSKIKTLLSKSNLQKT 229
            G+L D  K     SG   +   +P+ + S  +     VK  KK++ ++KT   K  L+K 
Sbjct: 1117 GQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKV 1176

Query: 230  PLSQSMSVLPTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQV 289
              + SM  +P                    D  ++ES    D    K +A  + K L + 
Sbjct: 1177 KETLSMEKIP---------------PMVTTDQKQEESKLEKD----KASALQEKKPLPEE 1217

Query: 290  NFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGF 349
               +P++E       +RS+                 LE+ +   E K   P +  S    
Sbjct: 1218 KKLIPEEE------KIRSEE------------KKPLLEEKKPTPEDKKLLPEAKTSAPEE 1259

Query: 350  RKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGD-- 407
            +K  L  S   +A    +E  EG       Q      +   K   LPS  P  L   D  
Sbjct: 1260 QKHDLLKSQVQIA----EEKLEGRVAPKTVQ---EGKQPQTKMEGLPSGTPQSLPKEDDK 1312

Query: 408  ----LRENMAP---ANSEATKEAKESKKPESRRSSLLSLMTGK-----------KDVAKG 449
                ++E   P   A  +  +  KE  + E  +S   S    K            D    
Sbjct: 1313 TTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISS 1372

Query: 450  SEGENPLTVPGREKEGMLMGVKP---GEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFE 506
            S GE P  +P  EK+ +L G+K     +++S  +   + + E    +++  Q S+L   +
Sbjct: 1373 SLGEIPSLIPTDEKD-ILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEK 1431

Query: 507  DVQITEP-EAEPES-KSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSS 563
              + T+P E  PE  K + +    S     T + +   E   E + T +  S  D PSS
Sbjct: 1432 SEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSS 1490



 Score = 38.5 bits (88), Expect = 0.042
 Identities = 98/492 (19%), Positives = 179/492 (36%), Gaps = 49/492 (9%)

Query: 188  TASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPTSKPEKVL 247
            ++S IIP +   VD        ++++K     L + +  ++    Q M + P S P +  
Sbjct: 2031 SSSFIIPESHEIVDLGTMVTSTEEERK----LLDADAAYEELMKRQQMQLTPGSSPTQAP 2086

Query: 248  LRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLN------QVNFTLPKKEGLSF 301
            +     +S  D D   D S ++S +     T ST    L+        +F+  + E    
Sbjct: 2087 IGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYV 2146

Query: 302  LGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDS-SPSSSPSPKGFRKKHLFSSTEN 360
                R   ++++  ++ +     Y E  E+   +  S +PS + S          S    
Sbjct: 2147 TDYTREIQEIIAHESLILT----YSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITT 2202

Query: 361  LAAGS--WKEPAEGGGLSSDRQLSESSTK------DSLKSMTLPSYRPAPLVSGDLRENM 412
            L + +  + EP +      D +   SST       D  + +++   R AP       +++
Sbjct: 2203 LDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHI 2262

Query: 413  APANSEATKEAKES--KKPESRRSSLLS--LMTGKKDVAKGSEGE--NPLTVPGREKEGM 466
              + S+      ES   KPE   +  +S  L+  +KD  K ++ E  N + +   E    
Sbjct: 2263 VISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRD 2322

Query: 467  LMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPP 526
               ++     S  +E +         A+  ++  S   F   +    E          P 
Sbjct: 2323 KKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPS 2382

Query: 527  ISS-PRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGAD 585
            +SS P  P+       L++S +  P    P P   P   PP P                 
Sbjct: 2383 VSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP--------------LP 2428

Query: 586  TQSSESPSVFSSLSSPIAAPISTSTPI--ESWPLVDRGQAKSEGPPLLPKAELQTESLTP 643
              +S  P++       +A+P++T+TP+      L      +S G   LP   + T +  P
Sbjct: 2429 PPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNG---LPVTRICTTAPPP 2485

Query: 644  VPNSGSSVLGSL 655
            VP   SS+   L
Sbjct: 2486 VPPKPSSIPSGL 2497



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 99/441 (22%), Positives = 158/441 (35%), Gaps = 76/441 (17%)

Query: 340 PSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKS-MTLPSY 398
           P+++ SP   RK+ L SS     +G   +P    G  +   LS+S T D+ +S   LP  
Sbjct: 73  PAAAESPSMHRKQELDSSHPPKQSGRPPDP----GRPAQPGLSKSRTTDTFRSEQKLPGR 128

Query: 399 RPAPLVSGDLRENMAPANSEATKEAKESKKP----ESRRSSLLSLMTGKK---DVAKGSE 451
            P+ +    L+E+ +   ++  +E K S  P    E    S +S +  K    D+   SE
Sbjct: 129 SPSTI---SLKESKS--RTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSE 183

Query: 452 GENPLTVPGRE----KEGMLMGV----------KPGEDASGPAEDLVRR--SEKDTAAVV 495
                T   ++    ++G   G+          KP     GP  D +++  + K  ++  
Sbjct: 184 ASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ 243

Query: 496 SRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTR--------AVKPRLEVSPE 547
             +  S        I  P   P++     P       PQT+        +VKP L  SP 
Sbjct: 244 PEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLP-SP- 301

Query: 548 AQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPIS 607
           ++P  + P+P   P+  P    S    + P              P+  S L+ P+A    
Sbjct: 302 SKPPIQQPTPGKPPAQQPGHEKSQPGPAKP--------------PAQPSGLTKPLAQQPG 347

Query: 608 TSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGT 667
           T  P    P+   G  K    PL P      ++ +  P+S      +L + P        
Sbjct: 348 TVKP----PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ 403

Query: 668 EDS-LMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGE---A 723
           +       T++ GT K          L +QP  G Q       P K     P  G+    
Sbjct: 404 QPGPAKPPTQQVGTPK---------PLAQQP--GLQSPAKAPGPTKTPVQQPGPGKIPAQ 452

Query: 724 QEVPFALSLSSDGAVSPVGEL 744
           Q  P   S    G   P  +L
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQL 473



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 86/438 (19%), Positives = 139/438 (31%), Gaps = 55/438 (12%)

Query: 202 SDDESVVKDKKKKSKI--KTLLSKSNLQKTPLSQSMSVLPTSKPEKVLLRPGDFQSQWDE 259
           SD E+  ++  KK K+  K       + K PL Q        KP      PG    Q D 
Sbjct: 180 SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQ-----PPKPIPKQQGPGRDPLQQDG 234

Query: 260 DDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCI 319
                 S     + S        ++   Q   T   K  L      R  +   ++    +
Sbjct: 235 TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQ-----RDASRPQTKQADIV 289

Query: 320 NGNHVYLEQPE-AKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSD 378
            G  V    P  +K  I+  +P   P+ +   +K           G  K PA+  GL+  
Sbjct: 290 RGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKS--------QPGPAKPPAQPSGLTKP 341

Query: 379 RQLSESSTKDSLK--SMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSL 436
                 + K  ++    T P  +P           + PA   A +   E  KP S +   
Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPAQP-----------LGPAKPPAQQTGSE--KPSSEQPGP 388

Query: 437 LSLM----TGKKDVAKGSEGENPLTVPGREKE-GMLMGVKPGEDASGPAEDLVRRSEKDT 491
            +L      GK    +    + P    G  K      G++    A GP +  V++     
Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK 448

Query: 492 AAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAP-------------QTRAV 538
                + G      +    T+P ++    ++P P    P  P             Q  + 
Sbjct: 449 IPA-QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST 507

Query: 539 KPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSL 598
           KP  +    A+P+ + P  T  PS  P     S Q   P++      T+          L
Sbjct: 508 KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567

Query: 599 SSPIAAPISTSTPIESWP 616
             P  +P +   P +  P
Sbjct: 568 QPPTVSPSAKQPPSQGLP 585



 Score = 31.2 bits (69), Expect = 6.7
 Identities = 33/123 (26%), Positives = 48/123 (39%), Gaps = 27/123 (21%)

Query: 1074 EEKPMGNGSPSPP-----PGTSLDNPVPSPSPSE--------IFPVTHSFPSSAHSDTHH 1120
            + KPM  GSP+PP      G ++  P  SP P E        +  +T + P S  +    
Sbjct: 867  DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDA-PKSQPTTPQE 925

Query: 1121 TST-----------AESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPGAGT 1169
            T T           +++    +  G  G     G   P+ QA  +PS+  P S  P   T
Sbjct: 926  TVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA-PAPSQP-PTSQGPPKST 983

Query: 1170 GSA 1172
            G A
Sbjct: 984  GQA 986


>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
           homolog 2 [Homo sapiens]
          Length = 1210

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 81/336 (24%), Positives = 125/336 (37%), Gaps = 67/336 (19%)

Query: 472 PGEDASGPAEDLVRRSEKDTAAVV---SRQGSSLNLFEDVQITEPEAEPESKSEPRPPIS 528
           P +D+   +     + + DT++     S+QG+S  L +D+Q+++ E     ++  +PP S
Sbjct: 388 PTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSS 447

Query: 529 SPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQS 588
           S                          +P  +P SLP   +S+  +S  SE    +D+ S
Sbjct: 448 S--------------------------APPSAPQSLPEPVASAHSSSAESESTSDSDS-S 480

Query: 589 SESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSG 648
           S+S S  SS  S    P+ T  P                PP   K +L    LT V    
Sbjct: 481 SDSESESSSSDSEENEPLETPAP-------------EPEPPTTNKWQLD-NWLTKVSQPA 526

Query: 649 SSVLGSLFKQP--SFPANKGTEDSLMGRTR-ETGTEKNTSSLELEESLPEQPETGRQEEE 705
           +   G    +P    P +KG+ DS   +   E+      SS +   + PE P  G++   
Sbjct: 527 APPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRS-- 584

Query: 706 LPRFPCKKQDYSPSSGEAQEV-------PFALSLSSDGAVSPVGELAAG----GDRDLES 754
                C+K        + Q V       P   S  +    S  GE   G    G RD  S
Sbjct: 585 -----CQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTS 639

Query: 755 QAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRK 790
           +    V++K R  A     P P  A  PS +    K
Sbjct: 640 KDKPKVKTKGRPRAAASNEPKP--AVPPSSEKKKHK 673



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 136/646 (21%), Positives = 218/646 (33%), Gaps = 111/646 (17%)

Query: 545  SPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAA 604
            +P     ++ P PT     +  +  +  Q    S+      T S+      S L   +  
Sbjct: 376  TPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSK------THSNSQQGTSSMLEDDLQL 429

Query: 605  PISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPAN 664
              S  +  E  P        S  PP  P++  +     PV ++ SS   S          
Sbjct: 430  SDSEDSDSEQTP---EKPPSSSAPPSAPQSLPE-----PVASAHSSSAES---------- 471

Query: 665  KGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQ 724
            + T DS       + +E  +SS + EE+ P   ET   E E            P +    
Sbjct: 472  ESTSDS----DSSSDSESESSSSDSEENEPL--ETPAPEPE------------PPTTNKW 513

Query: 725  EVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSI 784
            ++   L+  S  A  P G  +    R      GS   + +++ +E   PP    +  P  
Sbjct: 514  QLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRA 573

Query: 785  DSMM-----RKLEEMGLNLRKDQKKT------KKRVSFSEQLFTEEAVAGA---ALLVEG 830
                     R  ++        Q++T      KK V  S +  +  ++ G     LL  G
Sbjct: 574  PPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYG 633

Query: 831  HSSCPQELNPAWSVAGN---ASDGEP-PESPHAEDSERESVTTPGPATCGAPASPADHLL 886
                  +  P     G    A+  EP P  P + + ++   + P P+   +   PA   +
Sbjct: 634  SRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNV 693

Query: 887  LPSQEESFSEVPMSEASSAKDTPL-FRMEG-EDALVTQYQSKASDHEGLLSDPLSDLQLV 944
                 E F+ VP++E+     +    R  G   A+V Q  S+    +  L  PL D +L+
Sbjct: 694  EDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSR----KDRLPLPLRDTKLL 749

Query: 945  SDFK-----SPIMADLNLSLPS-IPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGA 998
            S  +       +M  + L L S IP+      R  + ED          + K S+     
Sbjct: 750  SPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSK 809

Query: 999  LSLGLVVPCPERGKGPSGEADRLVLGEGLCD---FRLQAPQASVTAPSEQT-TEFGIHKP 1054
            L+           K   GEA+R       CD    RL+    S ++ S  +  E    KP
Sbjct: 810  LA-----------KKRKGEAER------DCDNKKIRLEKEIKSQSSSSSSSHKESSKTKP 852

Query: 1055 HLGKSSSLDKQL--PGPSGGEEEKPMGNGSPSPPPGTSLDNPVPSPSPSEIFPVTHSFPS 1112
                S S  K++  P P     +KP                P    S  E        P 
Sbjct: 853  SRPSSQSSKKEMLPPPPVSSSSQKPA--------------KPALKRSRREADTCGQDPPK 898

Query: 1113 SAHS--DTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQAWVSPS 1156
            SA S    H  S+   Q++   +GS    E+ G        +  PS
Sbjct: 899  SASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPS 944


>gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo
           sapiens]
          Length = 778

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 7/99 (7%)

Query: 20  VQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERSLGAPVWREEATFELPSLLS 79
           V +T+++ R L+A    G SD Y   ++G +KY + +  ++L  P WRE+  F L     
Sbjct: 251 VSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLN-PQWREQFDFHLYE--- 306

Query: 80  SGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQ 118
                   + +T   +     D F+GR +VDL  L R+Q
Sbjct: 307 ---ERGGVIDITAWDKDAGKRDDFIGRCQVDLSALSREQ 342



 Score = 38.5 bits (88), Expect = 0.042
 Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 9/96 (9%)

Query: 20  VQVTVLQARGLRAKGPGGTSDAYAVIQV-GKEKYATSVSERSLGAPVWREEATFELPSLL 78
           + +T+ + + L A+  GGTSD Y   ++ GKE + + +  ++L  PVW E+A   +  L 
Sbjct: 42  LDITLRRGQSLAARDRGGTSDPYVKFKIGGKEVFRSKIIHKNLN-PVWEEKACILVDHL- 99

Query: 79  SSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDL 114
                    L + V        D F+G A +DL  L
Sbjct: 100 ------REPLYIKVFDYDFGLQDDFMGSAFLDLTQL 129


>gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Homo
           sapiens]
          Length = 999

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 7/99 (7%)

Query: 20  VQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERSLGAPVWREEATFELPSLLS 79
           V +T+++ R L+A    G SD Y   ++G +KY + +  ++L  P WRE+  F L     
Sbjct: 472 VSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLN-PQWREQFDFHLYE--- 527

Query: 80  SGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQ 118
                   + +T   +     D F+GR +VDL  L R+Q
Sbjct: 528 ---ERGGVIDITAWDKDAGKRDDFIGRCQVDLSALSREQ 563



 Score = 38.5 bits (88), Expect = 0.042
 Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 9/96 (9%)

Query: 20  VQVTVLQARGLRAKGPGGTSDAYAVIQV-GKEKYATSVSERSLGAPVWREEATFELPSLL 78
           + +T+ + + L A+  GGTSD Y   ++ GKE + + +  ++L  PVW E+A   +  L 
Sbjct: 263 LDITLRRGQSLAARDRGGTSDPYVKFKIGGKEVFRSKIIHKNLN-PVWEEKACILVDHL- 320

Query: 79  SSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDL 114
                    L + V        D F+G A +DL  L
Sbjct: 321 ------REPLYIKVFDYDFGLQDDFMGSAFLDLTQL 350


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 100/426 (23%), Positives = 150/426 (35%), Gaps = 38/426 (8%)

Query: 240  TSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHK-RTASTDLKQLNQVNFTLPKKEG 298
            TS  ++  LRP    +  DE+D E E     D+       A  D K +          E 
Sbjct: 973  TSSGDQKRLRPS---TSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLEL 1029

Query: 299  LSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSST 358
             S  GG   + + LS             E+ E + +  D S     S        L  ++
Sbjct: 1030 DS--GGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEAS 1087

Query: 359  ENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSE 418
            E     S +E  E   + + +  + SS++ S  S    S   +P  S D  E +     E
Sbjct: 1088 EKDEGDSDEE--ETVSIVTSKAEATSSSESSESSEFESSSESSPSSSED-EEEVVAREEE 1144

Query: 419  ATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGR---EKEGMLMGVKPGED 475
              +E +E    ES  S+      G +D  +  +GE     PG    +  GM   V    +
Sbjct: 1145 EEEEEEEMVAEESMASA------GPEDFEQ--DGEEAALAPGAPAVDSLGMEEEVDIETE 1196

Query: 476  ASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEA-----EPESKS-EPRPPISS 529
            A  P E      E      V     S    E+  +++  A     EP +K  E RPP+S 
Sbjct: 1197 AVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSP 1256

Query: 530  PRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHG------ 583
             RAP+       LEV PE      LP     P   PP P S       ++  H       
Sbjct: 1257 ERAPEHD-----LEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEP 1311

Query: 584  -ADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLT 642
             A+     +P +  SL+   +     +TP    PL       S   P +P +     + +
Sbjct: 1312 LAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPS 1371

Query: 643  PVPNSG 648
            P  +SG
Sbjct: 1372 PSLSSG 1377



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 74/318 (23%), Positives = 119/318 (37%), Gaps = 52/318 (16%)

Query: 593 SVFSSLSSPIA---APISTSTPIESWPLVDRGQ-AKSEGPPLLPKAELQTESLT------ 642
           S FS   +P+A    P    T   ++   D G+  ++  PP LP AE   +         
Sbjct: 395 SAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGP 454

Query: 643 PVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRET---GTEKNTSSLELE-ESLPEQPE 698
           P P++ S  LG    +P+F  +    DS    T E+   G EK   SL+   E L ++  
Sbjct: 455 PPPDTNSMELGG---RPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQR 511

Query: 699 TG----RQEEELPRFPCKKQDYSPSSGEAQEV-PFALSLSSDGAVSPVGELAAGGDRDLE 753
           T     R+ +       +    S SS +   + PF  + S  G   P    +      LE
Sbjct: 512 TKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTN-SQPGFRGPTPPSSRPSSTGLE 570

Query: 754 SQAGSLVESKARDAAEEVA--PPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVSF 811
             + + +     D   ++   P  P     P    ++ +  E+ L+L  D+  T +++  
Sbjct: 571 DISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMD- 629

Query: 812 SEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPESP-HAEDSERESVTTP 870
                            EG  S  +++          SD E P +P  + D  +  V TP
Sbjct: 630 -----------------EGQQSSGEDME--------ISDDEMPSAPITSADCPKPMVVTP 664

Query: 871 GPATCGAPASPADHLLLP 888
           G A   AP+  A  L LP
Sbjct: 665 GAAAVAAPSVLAPTLPLP 682



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 43/174 (24%), Positives = 66/174 (37%), Gaps = 20/174 (11%)

Query: 412 MAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGML---M 468
           +AP  + +    +    P SR SS     TG +D++       P  +P  +++  L   +
Sbjct: 543 LAPFGTNSQPGFRGPTPPSSRPSS-----TGLEDIS-------PTPLPDSDEDEELDLGL 590

Query: 469 GVKPGEDAS--GPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPP 526
           G +P  +     PA  L + +E     V  R  +S  + E  Q +  + E      P  P
Sbjct: 591 GPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAP 650

Query: 527 ISSPRAPQTRAVKP---RLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVP 577
           I+S   P+   V P    +       PT  LP P   P   PP P    Q   P
Sbjct: 651 ITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFP 704



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 46/212 (21%), Positives = 68/212 (32%), Gaps = 19/212 (8%)

Query: 376 SSDRQLSE-----SSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATK---EAKESK 427
           SS  QLS      ++++   +  T PS RP+     D+     P + E  +         
Sbjct: 535 SSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRP 594

Query: 428 KPESRRSSLLSLMTGKKDVAKGSEGENPLTVP----GREKEGMLMGVKPGEDASGPAEDL 483
            PE        L++   +VA    G+   T      G++  G  M +   E  S P    
Sbjct: 595 PPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSA 654

Query: 484 VRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLE 543
                       +   +   L   + +  P   P     P PP   P  P    + P   
Sbjct: 655 DCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPP 714

Query: 544 VSPEAQPTARLPSP-------TDSPSSLPPLP 568
             P A P   +P P          P  LPPLP
Sbjct: 715 PPPPAHPAVTVPPPPLPAPPGVPPPPILPPLP 746


>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
          Length = 863

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 112/448 (25%), Positives = 150/448 (33%), Gaps = 82/448 (18%)

Query: 372 GGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEAT---KEAKESKK 428
           GGG SS       +          P     P V G L+E  +P     T   ++A ES  
Sbjct: 254 GGGPSSSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTT 313

Query: 429 PESR----RSSL----LSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPA 480
           P       RSSL    L    G   +  G   E P+  P           KP E    P 
Sbjct: 314 PAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTP-------KPSEGTPAPR 366

Query: 481 EDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAP--QTRAV 538
           +D                           IT  +AEP+ K  P PP SSP  P   +R V
Sbjct: 367 KD------------------------PPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQV 402

Query: 539 K-PRLEVSPEAQPTARLPSPTDSP------SSLPPLPSSSGQASVPSELGHGADTQSSES 591
           +    E   +  PTA L S   +P            P++   A+ P+ LGH   T  S  
Sbjct: 403 ENGGTEEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPA-LGHPESTPKSLH 461

Query: 592 PSV-FSSLSSPIAAPISTSTPIESWPLVDRGQ--AKSEGPPLLPKAELQTESLTPVPNSG 648
           P    +  SSP            + PL       + SE P   P   L  ESL+    S 
Sbjct: 462 PWYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSATPSPALSVESLS--SESA 519

Query: 649 SSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPE-TGRQEEELP 707
           S   G+   +P       +E ++       GT  N  SL    SL    E    + E++P
Sbjct: 520 SQTAGAELLEPPAVPKSSSEPAV----HAPGTPGNPVSLSTNSSLASSGELVEPRVEQMP 575

Query: 708 ----------RFPCKKQDYSPSSGEAQEVPFAL-----SLSSDGAVSPVGELAAGGDRD- 751
                     R     Q   P SG A   P  L      + S G+ SP  ++ +    + 
Sbjct: 576 QASPGLAPRTRGSSGPQPAKPCSG-ATPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENP 634

Query: 752 ---LESQAGSLVESKARDAAEEVAPPLP 776
                S A S    KA   ++ V PP P
Sbjct: 635 FNRKPSPAASPATKKATKGSKPVRPPAP 662



 Score = 37.7 bits (86), Expect = 0.071
 Identities = 92/422 (21%), Positives = 141/422 (33%), Gaps = 39/422 (9%)

Query: 697  PETGRQEEELPRFPCKKQDY-SPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQ 755
            PE   Q    PR P K Q+  SP +G     P   S S+  A       ++    +L  Q
Sbjct: 274  PEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQ 333

Query: 756  AGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQL 815
            AGS   S       E+  P P G   PS  +   + +   + L + + K KK        
Sbjct: 334  AGS--SSLVNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPK-KKPAPLPPSS 390

Query: 816  FTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSERESVTTPGPATC 875
                    +  +  G +    + +P  S+     +   P     ED E E+   P  AT 
Sbjct: 391  SPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYN---PFEEEEEDKEEEAPAAPSLATS 447

Query: 876  GAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLS 935
             A   P      P     +  +  + +   K  P  R      L   + S+ S  E   +
Sbjct: 448  PALGHPES---TPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLAL-HASRLSHSEPPSA 503

Query: 936  DP---LSDLQLVSDFKSPIMADLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGETAKSS 992
             P   LS   L S+  S       L  P++P+ +S+      V   G        +  SS
Sbjct: 504  TPSPALSVESLSSESASQTAGAELLEPPAVPKSSSEPA----VHAPGTPGNPVSLSTNSS 559

Query: 993  TLDIGALSLGLVVPCPE-------RGKGPSG-EADRLVLGEGLCDFRLQAPQASVTAPSE 1044
                G L    V   P+       R +G SG +  +   G       L   ++ V +P  
Sbjct: 560  LASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGATPTPLLLVGDRSPVPSPGS 619

Query: 1045 QTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDNPVPSPSPSEIF 1104
             + +  +      KSS  +            KP    SP+    T    PV  P+P   F
Sbjct: 620  SSPQLQV------KSSCKENPF-------NRKPSPAASPATKKATKGSKPVRPPAPGHGF 666

Query: 1105 PV 1106
            P+
Sbjct: 667  PL 668


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 52/199 (26%), Positives = 84/199 (42%), Gaps = 20/199 (10%)

Query: 519 SKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLP-----SPTDSPSSLPPLPSSSGQ 573
           S + P PP SS   P+T A  P    + +A P++  P     +P   P++ P  PSS   
Sbjct: 173 SATTPAPP-SSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSS--- 228

Query: 574 ASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPK 633
            S P E      T S+ +P+  SS + P    +    P  S   +D   A +  PP    
Sbjct: 229 -SAPPETTAAPPTPSATTPAPLSSSAPPETTAV---PPTPSATTLDPSSASA--PPETTA 282

Query: 634 AELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETG---TEKNTSSLELE 690
           A     + TP P S  +   +     + P +  T  +L   T ET    T + T+S+  +
Sbjct: 283 APPTPSATTPAPPSSPAPQETTAAPITTPNSSPT--TLAPDTSETSAAPTHQTTTSVTTQ 340

Query: 691 ESLPEQPETGRQEEELPRF 709
            +  +QP +   + ++ RF
Sbjct: 341 TTTTKQPTSAPGQNKISRF 359



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 46/177 (25%), Positives = 75/177 (42%), Gaps = 15/177 (8%)

Query: 515 AEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDS-----PSSLPPLPS 569
           A PE+ + P  P ++ +AP + +  P    +P   P A  P+P  S      ++ PP PS
Sbjct: 184 APPETTAAPPTPSATTQAPPSSSAPPETTAAPPT-PPATTPAPPSSSAPPETTAAPPTPS 242

Query: 570 SSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPP 629
               A+ P+ L   A  +++  P    + S+    P S S P E+        A +  PP
Sbjct: 243 ----ATTPAPLSSSAPPETTAVP---PTPSATTLDPSSASAPPETTAAPPTPSATTPAPP 295

Query: 630 LLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSS 686
             P  +  T +    PNS  + L     + S      T  S+   T+ T T++ TS+
Sbjct: 296 SSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSV--TTQTTTTKQPTSA 350



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 51/251 (20%), Positives = 82/251 (32%), Gaps = 25/251 (9%)

Query: 513 PEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPT--DSPSSLPPLPSS 570
           P+  P   + P+ P  +P  P     K    V+P    T ++PS T   + + +  LP+ 
Sbjct: 72  PKLPPSPNNPPKFP--NPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNV 129

Query: 571 SGQASVPSELGHGADTQSSESPSVFSSLSSPIA---------------APISTSTPIESW 615
           +      + +    +  +S S +  + ++SP                 AP S+S P E+ 
Sbjct: 130 TFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETT 189

Query: 616 PLVDRGQA------KSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTED 669
                  A       S  PP    A     + TP P S S+   +    P+  A      
Sbjct: 190 AAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPL 249

Query: 670 SLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFA 729
           S       T      S+  L+ S    P         P         SP+  E    P  
Sbjct: 250 SSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPIT 309

Query: 730 LSLSSDGAVSP 740
              SS   ++P
Sbjct: 310 TPNSSPTTLAP 320


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 108/485 (22%), Positives = 168/485 (34%), Gaps = 63/485 (12%)

Query: 335 IKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMT 394
           I +S+P + P+      +   +S+ N A+   + PA G G  +    + S    S     
Sbjct: 70  IPESAPRAGPT------RSAGTSSRNPAS---RPPASGRGERAPPAKNTSPGPVSSPGRA 120

Query: 395 LPSYRPAPLVSGDLRENMAP--ANSEATKEAKESKKPESRRSSLLSLMTG-------KKD 445
             + RP PL    LR +     A  +AT+  K S      R        G       ++ 
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180

Query: 446 VAKGSEGENPLTVPGREK----EGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSS 501
            A G+E   P   P        EG    V    + S        R        + R  S 
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240

Query: 502 LNLFEDVQITEP-EAEPESKSEPRPPI--SSPRAPQTRAVKP------RLEVSPEAQPTA 552
                   ++ P  + P ++  PR P   S P+    +A++P      R + +P   P +
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300

Query: 553 RLPSPTDSPSSL---PPLPSSSGQASVPSELGHGADTQ--------SSESPSVFSSLSSP 601
             P  T SPS     P  P  +    +P+ L               S  +P    +L SP
Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360

Query: 602 IAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPN-------SGSSVLGS 654
            A P S + P  + P +    +    PP+     L + SL   P+         ++ LGS
Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS 420

Query: 655 LFKQPSFP----ANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFP 710
              Q +      + + T+ SL   +R   T  ++  L+   SLP  P         P   
Sbjct: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASP---------PLQT 471

Query: 711 CKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEE 770
                 SP S      P   +LSS  + SP   L++     LE+Q+     S     A  
Sbjct: 472 SLSPAVSPLSSPLTIHPLQ-ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL 530

Query: 771 VAPPL 775
             PPL
Sbjct: 531 TTPPL 535



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 68/253 (26%), Positives = 85/253 (33%), Gaps = 29/253 (11%)

Query: 515 AEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLP-----SPTDSPSSLPPLPS 569
           A P  +  P PP S P +P   A  P     P A P  ++P     SP  SPS+ PP   
Sbjct: 700 AAPPLQVPPSPPASPPMSPS--ATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757

Query: 570 SSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTP----IESWPLVDRGQAKS 625
               A+ P ++          SP        P  AP + +TP    + S P    GQA  
Sbjct: 758 PPLLAAPPLQVPPSPPASLPMSPLA----KPPPQAPPALATPPLQALPSPPASFPGQA-- 811

Query: 626 EGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQ--PSFPANKGTEDSLMGRTRETGTEKN 683
              P  P A L    L   P     VL +   Q  PS PA+   +      T    T  +
Sbjct: 812 ---PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS 868

Query: 684 TSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGE 743
              L L  +    P   R     P       D +  S  A   P  L     G   P G 
Sbjct: 869 GPRLTLALAPGPPPPPSRS----PSSTLSGPDLAGHSSSATSTPEELRGYDSG---PEGG 921

Query: 744 LAAGGDRDLESQA 756
            AA    D E  A
Sbjct: 922 AAASPPPDAELAA 934



 Score = 39.3 bits (90), Expect = 0.024
 Identities = 36/149 (24%), Positives = 51/149 (34%), Gaps = 10/149 (6%)

Query: 521 SEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSEL 580
           S P  P  SP A       P L   P   P +   SP  SPS+ PP  +    A+ P ++
Sbjct: 678 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQV 737

Query: 581 GHGADTQSSESPSVFSSLSSPIAAPISTSTPIE-------SWPLVDRGQAKSEGPPLLPK 633
                     SP   S+   P   P+  + P++       S P+    +   + PP L  
Sbjct: 738 PPSPPASPPMSP---SATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALAT 794

Query: 634 AELQTESLTPVPNSGSSVLGSLFKQPSFP 662
             LQ     P    G +        P  P
Sbjct: 795 PPLQALPSPPASFPGQAPFSPSASLPMSP 823



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 41/154 (26%), Positives = 59/154 (38%), Gaps = 29/154 (18%)

Query: 513 PEAEPESKSEPR---PPISSPRA-PQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLP 568
           P A P  ++ P    PP+ +P + P +  + P    SP+A P A       +P S PP P
Sbjct: 613 PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQA-PNALAVHLLQAPFSPPPSP 671

Query: 569 SSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGP 628
                 S P+            SP V  S + P  AP S + P    PL        + P
Sbjct: 672 PVQAPFSPPA------------SPPVSPSATPPSQAPPSLAAP----PL--------QVP 707

Query: 629 PLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFP 662
           P  P +   + S TP P +   +     + P  P
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 79/317 (24%), Positives = 114/317 (35%), Gaps = 53/317 (16%)

Query: 377 SDRQLSESSTKDSLKSMTLPSYRP--APL---VSGDLRENMAPANSEATK-------EAK 424
           S RQ   S T  S  + T P   P  APL    S  L+ +++PA S  +        +A 
Sbjct: 433 SPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL 492

Query: 425 ESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLV 484
            S    S ++ L SL      +    E ++ L  P  +         P    + P E+L 
Sbjct: 493 SSLASHSPQAPLSSL------IMPPLETQSSLAPPSLQ-------TPPASLTTPPLENL- 538

Query: 485 RRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSP--RAPQTRAVKPRL 542
                 + A    Q +S  L      T P   P     P  P+++P    P + A  P  
Sbjct: 539 -----PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593

Query: 543 EVSPEAQPTAR-LPSPTDSPSSLPP--------LPSSSGQASVP-SELGHGADTQSSESP 592
                A P  + LPSP  SP + PP        LP      S P S       T S ++P
Sbjct: 594 APPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP 653

Query: 593 SVFS--SLSSPIAAPISTS-----TPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVP 645
           +  +   L +P + P S       +P  S P+       S+ PP L    LQ   + P P
Sbjct: 654 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ---VPPSP 710

Query: 646 NSGSSVLGSLFKQPSFP 662
            +   +  S    P  P
Sbjct: 711 PASPPMSPSATPPPQAP 727



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 42/154 (27%), Positives = 61/154 (39%), Gaps = 28/154 (18%)

Query: 513 PEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPS--- 569
           P A P  ++  RPP   P    T    PRL ++    P    P P+ SPSS    P    
Sbjct: 846 PPASPTLQAPRRPPTPGP---DTSVSGPRLTLALAPGPP---PPPSRSPSSTLSGPDLAG 899

Query: 570 -SSGQASVPSEL---GHGADTQSSESPSVFSSLSS------------PIAAPISTSTPIE 613
            SS   S P EL     G +  ++ SP   + L++            P+A   +   P+ 
Sbjct: 900 HSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL- 958

Query: 614 SWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNS 647
            WP    G   ++G   + + E   ES TP P +
Sbjct: 959 PWPPA-TGPGSADGLCTIYETE-GPESATPAPGA 990


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 52/199 (26%), Positives = 84/199 (42%), Gaps = 20/199 (10%)

Query: 519 SKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLP-----SPTDSPSSLPPLPSSSGQ 573
           S + P PP SS   P+T A  P    + +A P++  P     +P   P++ P  PSS   
Sbjct: 173 SATTPAPP-SSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSS--- 228

Query: 574 ASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPK 633
            S P E      T S+ +P+  SS + P    +    P  S   +D   A +  PP    
Sbjct: 229 -SAPPETTAAPPTPSATTPAPLSSSAPPETTAV---PPTPSATTLDPSSASA--PPETTA 282

Query: 634 AELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETG---TEKNTSSLELE 690
           A     + TP P S  +   +     + P +  T  +L   T ET    T + T+S+  +
Sbjct: 283 APPTPSATTPAPPSSPAPQETTAAPITTPNSSPT--TLAPDTSETSAAPTHQTTTSVTTQ 340

Query: 691 ESLPEQPETGRQEEELPRF 709
            +  +QP +   + ++ RF
Sbjct: 341 TTTTKQPTSAPGQNKISRF 359



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 46/177 (25%), Positives = 75/177 (42%), Gaps = 15/177 (8%)

Query: 515 AEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDS-----PSSLPPLPS 569
           A PE+ + P  P ++ +AP + +  P    +P   P A  P+P  S      ++ PP PS
Sbjct: 184 APPETTAAPPTPSATTQAPPSSSAPPETTAAPPT-PPATTPAPPSSSAPPETTAAPPTPS 242

Query: 570 SSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPP 629
               A+ P+ L   A  +++  P    + S+    P S S P E+        A +  PP
Sbjct: 243 ----ATTPAPLSSSAPPETTAVP---PTPSATTLDPSSASAPPETTAAPPTPSATTPAPP 295

Query: 630 LLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSS 686
             P  +  T +    PNS  + L     + S      T  S+   T+ T T++ TS+
Sbjct: 296 SSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSV--TTQTTTTKQPTSA 350



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 51/251 (20%), Positives = 82/251 (32%), Gaps = 25/251 (9%)

Query: 513 PEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPT--DSPSSLPPLPSS 570
           P+  P   + P+ P  +P  P     K    V+P    T ++PS T   + + +  LP+ 
Sbjct: 72  PKLPPSPNNPPKFP--NPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNV 129

Query: 571 SGQASVPSELGHGADTQSSESPSVFSSLSSPIA---------------APISTSTPIESW 615
           +      + +    +  +S S +  + ++SP                 AP S+S P E+ 
Sbjct: 130 TFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETT 189

Query: 616 PLVDRGQA------KSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTED 669
                  A       S  PP    A     + TP P S S+   +    P+  A      
Sbjct: 190 AAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPL 249

Query: 670 SLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFA 729
           S       T      S+  L+ S    P         P         SP+  E    P  
Sbjct: 250 SSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPIT 309

Query: 730 LSLSSDGAVSP 740
              SS   ++P
Sbjct: 310 TPNSSPTTLAP 320


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 52/199 (26%), Positives = 84/199 (42%), Gaps = 20/199 (10%)

Query: 519 SKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLP-----SPTDSPSSLPPLPSSSGQ 573
           S + P PP SS   P+T A  P    + +A P++  P     +P   P++ P  PSS   
Sbjct: 173 SATTPAPP-SSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSS--- 228

Query: 574 ASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPK 633
            S P E      T S+ +P+  SS + P    +    P  S   +D   A +  PP    
Sbjct: 229 -SAPPETTAAPPTPSATTPAPLSSSAPPETTAV---PPTPSATTLDPSSASA--PPETTA 282

Query: 634 AELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETG---TEKNTSSLELE 690
           A     + TP P S  +   +     + P +  T  +L   T ET    T + T+S+  +
Sbjct: 283 APPTPSATTPAPPSSPAPQETTAAPITTPNSSPT--TLAPDTSETSAAPTHQTTTSVTTQ 340

Query: 691 ESLPEQPETGRQEEELPRF 709
            +  +QP +   + ++ RF
Sbjct: 341 TTTTKQPTSAPGQNKISRF 359



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 46/177 (25%), Positives = 75/177 (42%), Gaps = 15/177 (8%)

Query: 515 AEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDS-----PSSLPPLPS 569
           A PE+ + P  P ++ +AP + +  P    +P   P A  P+P  S      ++ PP PS
Sbjct: 184 APPETTAAPPTPSATTQAPPSSSAPPETTAAPPT-PPATTPAPPSSSAPPETTAAPPTPS 242

Query: 570 SSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPP 629
               A+ P+ L   A  +++  P    + S+    P S S P E+        A +  PP
Sbjct: 243 ----ATTPAPLSSSAPPETTAVP---PTPSATTLDPSSASAPPETTAAPPTPSATTPAPP 295

Query: 630 LLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSS 686
             P  +  T +    PNS  + L     + S      T  S+   T+ T T++ TS+
Sbjct: 296 SSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSV--TTQTTTTKQPTSA 350



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 51/251 (20%), Positives = 82/251 (32%), Gaps = 25/251 (9%)

Query: 513 PEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPT--DSPSSLPPLPSS 570
           P+  P   + P+ P  +P  P     K    V+P    T ++PS T   + + +  LP+ 
Sbjct: 72  PKLPPSPNNPPKFP--NPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNV 129

Query: 571 SGQASVPSELGHGADTQSSESPSVFSSLSSPIA---------------APISTSTPIESW 615
           +      + +    +  +S S +  + ++SP                 AP S+S P E+ 
Sbjct: 130 TFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETT 189

Query: 616 PLVDRGQA------KSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTED 669
                  A       S  PP    A     + TP P S S+   +    P+  A      
Sbjct: 190 AAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPL 249

Query: 670 SLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFA 729
           S       T      S+  L+ S    P         P         SP+  E    P  
Sbjct: 250 SSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPIT 309

Query: 730 LSLSSDGAVSP 740
              SS   ++P
Sbjct: 310 TPNSSPTTLAP 320


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 103/486 (21%), Positives = 163/486 (33%), Gaps = 61/486 (12%)

Query: 426  SKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVR 485
            S K  SR++S        KD  +G +G            G     +PG  A G       
Sbjct: 2299 SAKRRSRKTS--------KDTGEGKDG------------GTAGSEEPGAKARGRGRKPSA 2338

Query: 486  RSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISS--------PRAPQTRA 537
            +++ D AA +     +  +       EP + P SK  P  P+          P  PQ   
Sbjct: 2339 KAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSP 2398

Query: 538  VKPRLEVSPEAQPTARLPSPTDS--PSSLPPLPSS---SGQASVPSELGHGADTQSSESP 592
              P     P  +P A LP+P  S  P+ L  +P++     +A    E G     +  E  
Sbjct: 2399 APPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEA 2458

Query: 593  SVFSSLS-SPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSV 651
             +   L    + +P S           D G     G    PK+ L   S  P   +GSS 
Sbjct: 2459 ELLVKLDHEGVTSPKSKKAKEALLLREDPG----AGGWQEPKSLLSLGSYPPA--AGSS- 2511

Query: 652  LGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEES-LPEQPETGRQEEELPRFP 710
                  +P  P  K T+  L    +E G       L  E+S  P+ P+  + E++     
Sbjct: 2512 ------EPKAPWPKATDGDL---AQEPG-----PGLTFEDSGNPKSPDKAQAEQDGAEE- 2556

Query: 711  CKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEE 770
              +   S SSG +     + S  S+      G+    G      +  S   S+A   A  
Sbjct: 2557 -SESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASS 2615

Query: 771  VAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEG 830
             +      +S  S  S          +       +    S S    +  + + ++   + 
Sbjct: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDE 2675

Query: 831  HSSC--PQELNPAWSVAGNASDGEPPESPHAEDSERESVTTPGPAT-CGAPASPADHLLL 887
             SSC    E  PA +   +A    P ++       R S  +PG  T    P +P      
Sbjct: 2676 DSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQ 2735

Query: 888  PSQEES 893
            P Q ++
Sbjct: 2736 PLQPKA 2741



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 63/296 (21%), Positives = 98/296 (33%), Gaps = 28/296 (9%)

Query: 345  SPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLV 404
            SPK  + K      E+  AG W+EP     L S    + SS          P        
Sbjct: 2471 SPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSE---------PKAPWPKAT 2521

Query: 405  SGDLRENMAPA-NSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREK 463
             GDL +   P    E +   K   K ++ +       +     +  S   +  +  G E 
Sbjct: 2522 DGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSET 2581

Query: 464  EGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEP 523
            EG   G K G+   G      R     ++   S   SS +       +   +   S S  
Sbjct: 2582 EGEEEGDKNGDGGCGTGG---RNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSS 2638

Query: 524  RPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSL--------PPLPSSSGQAS 575
                SS  +  + +       S  +  ++   S TD  SS          P    S QA+
Sbjct: 2639 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAA 2698

Query: 576  VPSELGH--GADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPP 629
            +P++     G    S+ SP   +    P A P     P  + PL  + QA ++  P
Sbjct: 2699 LPTKATKQAGKARPSAHSPGKKTPAPQPQAPP-----PQPTQPLQPKAQAGAKSRP 2749



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 44/234 (18%), Positives = 85/234 (36%), Gaps = 19/234 (8%)

Query: 320  NGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDR 379
            +GN    ++ +A+ +  + S SSS S  G       SS+ + ++GS  E  E G  + D 
Sbjct: 2538 SGNPKSPDKAQAEQDGAEESESSSSSSSGSSS----SSSSSSSSGSETEGEEEGDKNGDG 2593

Query: 380  QLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSL 439
                     S  S    S  PA   S     + + ++S ++  +  S    S  SS  S 
Sbjct: 2594 GCGTGGRNCSAASSRAAS--PASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2651

Query: 440  MTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQG 499
             +     +  S   +  +    +++         +D + PA      ++       ++Q 
Sbjct: 2652 SSSSSSSSSSSSSSSSSSSSTTDEDSSCSS----DDEAAPAPTAGPSAQAALPTKATKQA 2707

Query: 500  SSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTAR 553
                         P A    K  P P   +P    T+ ++P+ +   +++P  R
Sbjct: 2708 GK---------ARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKR 2752


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.306    0.125    0.347 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,464,500
Number of Sequences: 37866
Number of extensions: 3215929
Number of successful extensions: 18893
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 118
Number of HSP's successfully gapped in prelim test: 1174
Number of HSP's that attempted gapping in prelim test: 13639
Number of HSP's gapped (non-prelim): 5593
length of query: 1283
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1169
effective length of database: 13,930,794
effective search space: 16285098186
effective search space used: 16285098186
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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