BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo sapiens] (1283 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo s... 2521 0.0 gi|50363230 RAB11 family interacting protein 1 isoform 2 [Homo s... 1212 0.0 gi|50363228 RAB11 family interacting protein 1 isoform 1 [Homo s... 1060 0.0 gi|24308075 RAB11 family interacting protein 5 (class I) [Homo s... 265 3e-70 gi|7662394 RAB11 family interacting protein 2 (class I) [Homo sa... 253 8e-67 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 64 9e-10 gi|148806908 fibronectin type III domain containing 1 [Homo sapi... 64 1e-09 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 60 1e-08 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 60 1e-08 gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 60 1e-08 gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 59 2e-08 gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 58 7e-08 gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 58 7e-08 gi|91982772 mucin 17 [Homo sapiens] 57 9e-08 gi|209862789 microtubule associated monoxygenase, calponin and L... 57 1e-07 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 57 1e-07 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 57 1e-07 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 57 1e-07 gi|150170670 piccolo isoform 2 [Homo sapiens] 54 7e-07 gi|150378539 piccolo isoform 1 [Homo sapiens] 54 7e-07 gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 54 1e-06 gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo... 53 2e-06 gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Hom... 53 2e-06 gi|210032580 SET domain containing 1B [Homo sapiens] 52 3e-06 gi|31324577 molecule interacting with Rab13 [Homo sapiens] 52 3e-06 gi|222418647 mucin 7, secreted precursor [Homo sapiens] 52 4e-06 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 52 4e-06 gi|222418649 mucin 7, secreted precursor [Homo sapiens] 52 4e-06 gi|222418645 mucin 7, secreted precursor [Homo sapiens] 52 4e-06 gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 52 4e-06 >gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo sapiens] Length = 1283 Score = 2521 bits (6534), Expect = 0.0 Identities = 1283/1283 (100%), Positives = 1283/1283 (100%) Query: 1 MSLMVSAGRGLGAVWSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERS 60 MSLMVSAGRGLGAVWSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERS Sbjct: 1 MSLMVSAGRGLGAVWSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERS 60 Query: 61 LGAPVWREEATFELPSLLSSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQGR 120 LGAPVWREEATFELPSLLSSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQGR Sbjct: 61 LGAPVWREEATFELPSLLSSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQGR 120 Query: 121 RKTQWYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGK 180 RKTQWYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGK Sbjct: 121 RKTQWYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGK 180 Query: 181 NKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPT 240 NKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPT Sbjct: 181 NKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPT 240 Query: 241 SKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLS 300 SKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLS Sbjct: 241 SKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLS 300 Query: 301 FLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTEN 360 FLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTEN Sbjct: 301 FLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTEN 360 Query: 361 LAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEAT 420 LAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEAT Sbjct: 361 LAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEAT 420 Query: 421 KEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPA 480 KEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPA Sbjct: 421 KEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPA 480 Query: 481 EDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP 540 EDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP Sbjct: 481 EDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP 540 Query: 541 RLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSS 600 RLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSS Sbjct: 541 RLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSS 600 Query: 601 PIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPS 660 PIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPS Sbjct: 601 PIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPS 660 Query: 661 FPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSS 720 FPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSS Sbjct: 661 FPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSS 720 Query: 721 GEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGAS 780 GEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGAS Sbjct: 721 GEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGAS 780 Query: 781 VPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNP 840 VPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNP Sbjct: 781 VPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNP 840 Query: 841 AWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMS 900 AWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMS Sbjct: 841 AWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMS 900 Query: 901 EASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLP 960 EASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLP Sbjct: 901 EASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLP 960 Query: 961 SIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADR 1020 SIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADR Sbjct: 961 SIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADR 1020 Query: 1021 LVLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGN 1080 LVLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGN Sbjct: 1021 LVLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGN 1080 Query: 1081 GSPSPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVE 1140 GSPSPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVE Sbjct: 1081 GSPSPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVE 1140 Query: 1141 NFGKRKPLLQAWVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNATATKVANCSLGTATII 1200 NFGKRKPLLQAWVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNATATKVANCSLGTATII Sbjct: 1141 NFGKRKPLLQAWVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNATATKVANCSLGTATII 1200 Query: 1201 SENLNNEVMMKKYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLV 1260 SENLNNEVMMKKYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLV Sbjct: 1201 SENLNNEVMMKKYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLV 1260 Query: 1261 RVMEETPNILRIPTQVGKKAGKM 1283 RVMEETPNILRIPTQVGKKAGKM Sbjct: 1261 RVMEETPNILRIPTQVGKKAGKM 1283 >gi|50363230 RAB11 family interacting protein 1 isoform 2 [Homo sapiens] Length = 612 Score = 1212 bits (3135), Expect = 0.0 Identities = 611/612 (99%), Positives = 611/612 (99%) Query: 672 MGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALS 731 MGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALS Sbjct: 1 MGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALS 60 Query: 732 LSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKL 791 LSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKL Sbjct: 61 LSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKL 120 Query: 792 EEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDG 851 EEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDG Sbjct: 121 EEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDG 180 Query: 852 EPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLF 911 EPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLF Sbjct: 181 EPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLF 240 Query: 912 RMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDER 971 RMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDER Sbjct: 241 RMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDER 300 Query: 972 IDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFR 1031 IDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFR Sbjct: 301 IDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFR 360 Query: 1032 LQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSL 1091 LQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSL Sbjct: 361 LQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSL 420 Query: 1092 DNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQA 1151 DNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQA Sbjct: 421 DNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQA 480 Query: 1152 WVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNATATKVANCSLGTATIISENLNNEVMMK 1211 WVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNA ATKVANCSLGTATIISENLNNEVMMK Sbjct: 481 WVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNAMATKVANCSLGTATIISENLNNEVMMK 540 Query: 1212 KYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILR 1271 KYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILR Sbjct: 541 KYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILR 600 Query: 1272 IPTQVGKKAGKM 1283 IPTQVGKKAGKM Sbjct: 601 IPTQVGKKAGKM 612 >gi|50363228 RAB11 family interacting protein 1 isoform 1 [Homo sapiens] Length = 649 Score = 1060 bits (2741), Expect = 0.0 Identities = 544/552 (98%), Positives = 544/552 (98%) Query: 1 MSLMVSAGRGLGAVWSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERS 60 MSLMVSAGRGLGAVWSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERS Sbjct: 1 MSLMVSAGRGLGAVWSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERS 60 Query: 61 LGAPVWREEATFELPSLLSSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQGR 120 LGAPVWREEATFELPSLLSSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQGR Sbjct: 61 LGAPVWREEATFELPSLLSSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQGR 120 Query: 121 RKTQWYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGK 180 RKTQWYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGK Sbjct: 121 RKTQWYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGK 180 Query: 181 NKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPT 240 NKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPT Sbjct: 181 NKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPT 240 Query: 241 SKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLS 300 SKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLS Sbjct: 241 SKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLS 300 Query: 301 FLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTEN 360 FLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTEN Sbjct: 301 FLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTEN 360 Query: 361 LAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEAT 420 LAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEAT Sbjct: 361 LAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEAT 420 Query: 421 KEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPA 480 KEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPA Sbjct: 421 KEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPA 480 Query: 481 EDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP 540 EDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP Sbjct: 481 EDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP 540 Query: 541 RLEVSPEAQPTA 552 RL TA Sbjct: 541 RLHPVKPMNATA 552 Score = 223 bits (569), Expect = 7e-58 Identities = 138/248 (55%), Positives = 155/248 (62%), Gaps = 18/248 (7%) Query: 1041 APSEQTTEFGIHKPHLGKSSSLDKQLPGPS----GGEEEKPMGNGSPSPPPGTSLDNPVP 1096 A SE T E K + SSL + G G E E P+ PG + + Sbjct: 415 ANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPL------TVPGREKEGMLM 468 Query: 1097 SPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRV-ENFGKRKPLLQAWVSP 1155 P E S D S ++ + +GS+ + E+ +P + Sbjct: 469 GVKPGED-------ASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKS 521 Query: 1156 SETHPVSAQPGAGTGSAKHRLHPVKPMNATATKVANCSLGTATIISENLNNEVMMKKYSP 1215 P+S+ T + K RLHPVKPMNATATKVANCSLGTATIISENLNNEVMMKKYSP Sbjct: 522 EPRPPISSPRAPQTRAVKPRLHPVKPMNATATKVANCSLGTATIISENLNNEVMMKKYSP 581 Query: 1216 SDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRIPTQ 1275 SDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRIPTQ Sbjct: 582 SDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRIPTQ 641 Query: 1276 VGKKAGKM 1283 VGKKAGKM Sbjct: 642 VGKKAGKM 649 >gi|24308075 RAB11 family interacting protein 5 (class I) [Homo sapiens] Length = 653 Score = 265 bits (676), Expect = 3e-70 Identities = 193/501 (38%), Positives = 264/501 (52%), Gaps = 52/501 (10%) Query: 15 WSPTHVQVTVLQARGLRAK--GPGGTSDAYAVIQVGKEKYATSVSERSLGAPVWREEATF 72 W PTHVQVTVL+ARGLR K G G TSDAY VIQVG+EKY+TSV E++ G P WREE +F Sbjct: 16 WLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVEKTHGCPEWREECSF 75 Query: 73 ELP-----SLL-----SSGPA-------AAATLQLTVLHRALLGLDKFLGRAEVDLRDLH 115 ELP LL +GPA AA L LT +HR+L+G+DKFLG+A V L ++ Sbjct: 76 ELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGVDKFLGQATVALDEVF 135 Query: 116 RDQGRRKTQWYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKD 175 + TQWYKL SKPGKK+KERGEIEV IQF RNN++ASMFDLSMKDK R+PF K++D Sbjct: 136 GAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDLSMKDKPRSPFSKIRD 195 Query: 176 KIKGKNKDSGSDTASAIIPSTTPSVDSDDESVVK-DKKKKSKIKTLLSKSNLQK------ 228 K+KGK K ++ASAI+PS+ D D S+ K K K ++ L KS+L + Sbjct: 196 KMKGKKK-YDLESASAILPSSAIE-DPDLGSLGKMGKAKGFFLRNKLRKSSLTQSNTSLG 253 Query: 229 --TPLSQSMSVLPTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQL 286 + LS + L P LL +S W + +S+ + + +HKRT S + Q+ Sbjct: 254 SDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLFTHKRTYSDEANQM 313 Query: 287 NQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSP 346 P + L G L D SRS++C+NG+H+Y E+P+ + S S PS Sbjct: 314 R----VAPPRALLDLQGHL----DAASRSSLCVNGSHIYNEEPQGPVRHRSSISGSLPSS 365 Query: 347 KGFRKKHLFSSTENLAA--GSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRP---- 400 + S E + +W + SS+ L + K + + P Sbjct: 366 GSLQAVSSRFSEEGPRSTDDTWPRGSRSNS-SSEAVLGQEELSAQAKVLAPGASHPGEEE 424 Query: 401 -APLVSGDLRENMAP--ANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLT 457 A L G + P A+SEA E KE + E R+ + + +++ G Sbjct: 425 GARLPEGKPVQVATPIVASSEAVAE-KEGARKEERKPRMGLFHHHHQGLSRSELGRRSSL 483 Query: 458 VPGREKEGMLMGVKPGEDASG 478 EK G ++G P +SG Sbjct: 484 ---GEKGGPILGASPHHSSSG 501 Score = 72.0 bits (175), Expect = 3e-12 Identities = 49/161 (30%), Positives = 85/161 (52%), Gaps = 14/161 (8%) Query: 1119 HHTSTAESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPGAGTGSAKHRLHP 1178 HH+S+ E + K++ G R +KP SP P+SA P G+ K Sbjct: 496 HHSSSGEEKAKSSWFGL--REAKDPTQKP------SPHPVKPLSAAPVEGSPDRKQSRSS 547 Query: 1179 VK-PMNATATKVANCSLGTATIISE-----NLNNEVMMKKYSPSDPAFAYAQLTHDELIQ 1232 + +++ K+ + G+ +++ + + +K + D + Y LTHDELI Sbjct: 548 LSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSAVLDQSAKYYHLTHDELIS 607 Query: 1233 LVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRIP 1273 L+L+++ +S+++ V+ELE YID LLVR+ME +P +L+IP Sbjct: 608 LLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQIP 648 >gi|7662394 RAB11 family interacting protein 2 (class I) [Homo sapiens] Length = 512 Score = 253 bits (646), Expect = 8e-67 Identities = 160/345 (46%), Positives = 208/345 (60%), Gaps = 21/345 (6%) Query: 15 WSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERSLGAPVWREEATFEL 74 W PTHVQVTVLQA+ L+ KG GT+D Y +IQ+GKEKY+TSV+E++L PVW+EEA+FEL Sbjct: 10 WFPTHVQVTVLQAKDLKPKGKSGTNDTYTIIQLGKEKYSTSVAEKTL-EPVWKEEASFEL 68 Query: 75 PSLLSSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQGRRKTQWYKLKSKPGK 134 P LL G L L V+HR+L+GLDKFLG+ ++L D+ D+ RRKT+W++L+SK GK Sbjct: 69 PGLLIQGSPEKYILFLIVMHRSLVGLDKFLGQVAINLNDIFEDKQRRKTEWFRLESKQGK 128 Query: 135 KDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKG-KNKDSGSDTASAII 193 + K RGEI+V+IQFMRNNMTASMFDLSMKDK+R+PF KLKDK+KG KN + SDT+SAII Sbjct: 129 RIKNRGEIKVNIQFMRNNMTASMFDLSMKDKTRSPFAKLKDKMKGRKNDGTFSDTSSAII 188 Query: 194 PST-TPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPTSKPEKVLLRPGD 252 PST P +S+ S K K K LL L + SMS L S L+ G Sbjct: 189 PSTHMPDANSEFSSGEIQMKSKPKKPFLLGPQRLSS---AHSMSDLSGSHMSSEKLKAGT 245 Query: 253 FQS------QWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLSFLGGLR 306 Q D ES S H+RT S D ++NQ + + + E L F Sbjct: 246 IGQTHLLGHQLDSFGTVPESGSLKS--PHRRTLSFDTSKMNQPDSIVDEGE-LCF----G 298 Query: 307 SKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRK 351 +ND +NV + + P K ++SS + S F K Sbjct: 299 RQNDPF--TNVTASLPQKFATLPRKKNPFEESSETWDSSMNLFSK 341 Score = 83.6 bits (205), Expect = 1e-15 Identities = 38/69 (55%), Positives = 53/69 (76%) Query: 1214 SPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRIP 1273 +P D Y LT++E++Q ++K KE + +K+ +RELEDYIDNLLVRVMEETP+ILR+P Sbjct: 440 NPFDATAGYRSLTYEEVLQELVKHKELLRRKDTHIRELEDYIDNLLVRVMEETPSILRVP 499 Query: 1274 TQVGKKAGK 1282 + +KAGK Sbjct: 500 YEPSRKAGK 508 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 63.9 bits (154), Expect = 9e-10 Identities = 113/528 (21%), Positives = 204/528 (38%), Gaps = 55/528 (10%) Query: 417 SEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDA 476 ++ T+E E ++ E+ K++ K EG G E+E P E+A Sbjct: 464 TQVTEEVTEEEEKEA-----------KEEEGKEEEGGEEEEAEGGEEE---TKSPPAEEA 509 Query: 477 SGP---AEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAP 533 + P A+ V+ K A S + +V+ E P + PP ++P Sbjct: 510 ASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPP--EAKSP 567 Query: 534 QTRAVKPRLEV-SPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQS--SE 590 + K EV SPE A+ P+ ++ S ++ V E A+ +S E Sbjct: 568 EKEEAKSPAEVKSPE---KAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE 624 Query: 591 SPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSS 650 + + SP A T +S + + P K+ ++ E+ + P S Sbjct: 625 EAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKS--PEKAKS 682 Query: 651 VLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEE----EL 706 + + K P + E++ EK S ++ E PE+ ++ +EE E Sbjct: 683 PVKAEAKSPEKAKSPVKEEA-------KSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEK 735 Query: 707 PRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARD 766 + P K++ SP ++ E L + S A +P E A +A S V+ + + Sbjct: 736 AKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVK- 794 Query: 767 AAEEVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAAL 826 + E+ PL A P + + K EE+ +++++K + +V + EE Sbjct: 795 SPEKAKSPLKEDAKAP--EKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPK 852 Query: 827 LVEGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPA-DHL 885 E S +E A E P+ P E+ + +V P + A A D Sbjct: 853 TEEKKDSKKEE----------APKKEAPK-PKVEEKKEPAVEKPKESKVEAKKEEAEDKK 901 Query: 886 LLPSQE-ESFSEVPMSEASSAKD-TPLFRMEGEDALVTQYQSKASDHE 931 +P+ E E+ ++V + E + K+ T + + E +DA + A E Sbjct: 902 KVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKE 949 Score = 52.4 bits (124), Expect = 3e-06 Identities = 107/531 (20%), Positives = 189/531 (35%), Gaps = 44/531 (8%) Query: 364 GSWKEPAEGGGLSSDRQLSE---SSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEAT 420 G +E AEGG + +E S K++ + + PA S + E +PA ++ Sbjct: 488 GGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSP 547 Query: 421 KEAK-----------ESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMG 469 ++AK E+K PE + + + + ++ E + E Sbjct: 548 EKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP 607 Query: 470 VKPGEDASGPAE--DLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPI 527 VK E+A PAE V+ K A V S + + E+ + E PE K E + P Sbjct: 608 VK--EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE-KEEAKSPE 664 Query: 528 SSPRAPQTRAVKPRLEVSP---EAQPTARLPSPTDSPSSLPPLPSS--SGQASVPSELGH 582 + + A P SP EA+ + SP + P S +A P + Sbjct: 665 KAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKS 724 Query: 583 GADTQSSESPSVFSSLSSPIAAPISTSTPIESWPL-VDRGQAKSEGPPLLPKAELQTESL 641 ++ S + +P +P ++ L V +AK+ P E Sbjct: 725 PVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKT------PAKEEARSPA 778 Query: 642 TPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGR 701 P S + K P + ED+ EK E E P + E Sbjct: 779 DKFPEKAKSPVKEEVKSPEKAKSPLKEDA-------KAPEKEIPKKE-EVKSPVKEEEKP 830 Query: 702 QEEELPRFPCK-KQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLV 760 QE ++ P K +++ +P++ + +E + + +P ++ + +E S V Sbjct: 831 QEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKV 890 Query: 761 ESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEA 820 E+K +A ++ P P + ++ + + K + K S+ +EA Sbjct: 891 EAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEA 950 Query: 821 VAGAALLVEGHSSCPQELNPAWSVAGNASD---GEPPESPHAEDSERESVT 868 E + P+E P D + P P AE +E+ S T Sbjct: 951 APEKKDTKEEKAKKPEE-KPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSST 1000 Score = 40.4 bits (93), Expect = 0.011 Identities = 72/373 (19%), Positives = 132/373 (35%), Gaps = 46/373 (12%) Query: 128 LKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGKNKDSGSD 187 +K++ +K + ++ + + + + +K+++P +K++ K K Sbjct: 670 VKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSP---VKEEAKSPEKAKSPV 726 Query: 188 TASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPTSKPEKVL 247 A P S ++ + K K KTL KS KTP + PEK Sbjct: 727 KEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKA- 785 Query: 248 LRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLSFLGGLRS 307 S + + A + LK+ + P+KE + Sbjct: 786 ------------------KSPVKEEVKSPEKAKSPLKE----DAKAPEKE-------IPK 816 Query: 308 KNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTE--NLAAGS 365 K +V S V +++P K E + + + K KK E Sbjct: 817 KEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEE 876 Query: 366 WKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAP-ANSEATK--- 421 KEPA S + + +D K T PA + +++E+ P +E K Sbjct: 877 KKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKV---EVKEDAKPKEKTEVAKKEP 933 Query: 422 ---EAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASG 478 +AKE KP ++ + K++ AK E E P T +++ + +P + + Sbjct: 934 DDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPE-EKPKTEAKAKEDDKTLSKEPSKPKAE 992 Query: 479 PAEDLVRRSEKDT 491 AE +KD+ Sbjct: 993 KAEKSSSTDQKDS 1005 Score = 34.7 bits (78), Expect = 0.60 Identities = 83/426 (19%), Positives = 146/426 (34%), Gaps = 42/426 (9%) Query: 555 PSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIES 614 P P P LP +PS S V SE +S + + + + E Sbjct: 417 PIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEK 476 Query: 615 WPLVDRGQAKSEG--------------PPLLPKAELQTESLTPVPNSGSSVLGSLFKQPS 660 + G+ + G PP A + E+ +PV K P+ Sbjct: 477 EAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEA--------KSPA 528 Query: 661 FPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSS 720 A ++ EK S + E P + ++ +EE K + + S Sbjct: 529 -EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSP 587 Query: 721 GEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGAS 780 + + A + S + A SPV E A ++A S V+ +A+ AE +P A Sbjct: 588 AKEEAKSPAEAKSPEKAKSPVKEEAKS-----PAEAKSPVKEEAKSPAEVKSPE---KAK 639 Query: 781 VPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNP 840 P+ + K E + K++ K+ ++ S ++ A V+ + P++ Sbjct: 640 SPTKEE--AKSPEKAKSPEKEEAKSPEKAK-SPVKAEAKSPEKAKSPVKAEAKSPEKAKS 696 Query: 841 AWSVAGNASDGEPPESPHAEDSER-ESVTTPGPATCGAPASPADHLLLPSQEESFSEVPM 899 V A E +SP E+++ E +P P P +EE+ S Sbjct: 697 --PVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKS----PVKEEAKSPEKA 750 Query: 900 SEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPL-SDLQLVSDFKSPIMADLNLS 958 AK + E + + +S A P+ +++ KSP+ D Sbjct: 751 KSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAP 810 Query: 959 LPSIPE 964 IP+ Sbjct: 811 EKEIPK 816 >gi|148806908 fibronectin type III domain containing 1 [Homo sapiens] Length = 1894 Score = 63.5 bits (153), Expect = 1e-09 Identities = 191/889 (21%), Positives = 310/889 (34%), Gaps = 170/889 (19%) Query: 329 PEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKD 388 P + PS SP+G K L +N K A GG + ++ + + Sbjct: 480 PSPRAPASSQHPSVPASPQGRNAKDLLLDLKN------KILANGGAPRKPQLRAKKAEEL 533 Query: 389 SLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAK 448 L+S + RE+ +P + T++ K + +P SR S++ + + Sbjct: 534 DLQSTEITGEEEL-----GSRED-SPMSPSDTQDQKRTLRPPSRHGH--SVVAPGRTAVR 585 Query: 449 GSEGENPLTVPGREKEGMLMGV--KPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFE 506 P G +K G + +PG S A S + T+ S +SLN + Sbjct: 586 ARMPALPRR-EGVDKPGFSLATQPRPGAPPSASASPAHHASTQGTSHRPSLP-ASLNDND 643 Query: 507 DVQITEPEAEPESK------SEPRPPISSPRAPQTRAVKPRLEVSPEAQPTA---RLP-- 555 V E E S ++PRP +S R + ++ R V P A+P + R P Sbjct: 644 LVDSDEDERAVGSLHPKGAFAQPRPALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHS 703 Query: 556 --SPTDSPSSLPP----------------LPSSSGQASVPSELGHGADTQSSESPSVFSS 597 + DS +S PP P S S + G A +S +PS S+ Sbjct: 704 GAAEEDSSASAPPSRLSPPHGGSSRLLPTQPHLSSPLSKGGKDGEDAPATNSNAPS-RST 762 Query: 598 LSSPIAAPISTSTPIESWPLVDRGQAKSEG--PPLLPKAELQTESLTPVPNSGSSVLGSL 655 +SS +++ +S+ T + G++ +G +AE ++L P SG L Sbjct: 763 MSSSVSSHLSSRTQVSEGAEASDGESHGDGDREDGGRQAEATAQTLRARPASGHF---HL 819 Query: 656 FKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQD 715 + F AN G S R + ++S P++ PR P Sbjct: 820 LRHKPFAAN-GRSPSRFSIGRGPRLQPSSS-----------PQSTVPSRAHPRVPSHSDS 867 Query: 716 YSP-SSG----EAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEE 770 + SSG E E P ++ +D S + + G DL S R A+ Sbjct: 868 HPKLSSGIHGDEEDEKPLPATVVNDHVPSSSRQPISRGWEDLR-------RSPQRGASLH 920 Query: 771 VAPPLPMGASVPSID--------SMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVA 822 P+P D S+ K +++ + D + + Sbjct: 921 RKEPIPENPKSTGADTHPQGKYSSLASKAQDVQQSTDADTEGHSPKAQPGSTDRHASPAR 980 Query: 823 GAALLVEGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPA 882 A + H S P+ + P G A +PP P S+ PGP + A SP+ Sbjct: 981 PPAARSQQHPSVPRRMTP-----GRAPQQQPP--PPVATSQHH----PGPQSRDAGRSPS 1029 Query: 883 DHLLLPSQEESFSEVPMSEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQ 942 L S ++ P S+ S + + L T Q++ D +G D ++++ Sbjct: 1030 QPRL--SLTQAGRPRPTSQGRSHSSSDPYTASSRGMLPTALQNQDEDAQGSYDDDSTEVE 1087 Query: 943 LVSDFKSPIMA----DLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGA 998 D ++P A + SLP +V S GD G A Sbjct: 1088 -AQDVRAPAHAARAKEAAASLPKHQQVESP----TGAGAGGDHRSQRGHAAS-------- 1134 Query: 999 LSLGLVVPCPERGKGPSGEADRLVLGEGLCDFRLQAP---------QASVTAPSEQTTEF 1049 P R P G R + + + P Q SV+A ++ + Sbjct: 1135 ---------PARPSRPGGPQSRARVPSRAAPGKSEPPSKRPLSSKSQQSVSAEDDEEEDA 1185 Query: 1050 GIHKPHLGKSSSLDKQLP------GPSGG---------EEEKPM-------GNGSP---- 1083 G K GK L +P P GG EE +P G+ +P Sbjct: 1186 GFFKG--GKEDLLSSSVPKWPSSSTPRGGKDADGSLAKEEREPAIALAPRGGSLAPVKRP 1243 Query: 1084 -SPPPGTS-----LDNPVPSPSPSEIFPV--THSFPS-SAHSDTHHTST 1123 PPPG+S + + +P S + + PV TH +P + + H ST Sbjct: 1244 LPPPPGSSPRASHVPSRLPPRSAATVSPVAGTHPWPQYTTRAPPGHFST 1292 Score = 32.3 bits (72), Expect = 3.0 Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 8/100 (8%) Query: 452 GENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRR--SEKDTAAVVSRQGSSLNLFEDVQ 509 G LT PG ++ G++PGE RR A +V+ +S E Q Sbjct: 407 GAKSLTYPGDTTSALVDGLQPGERYLFKIRATNRRGLGPHSKAFIVAMPTTSKADVE--Q 464 Query: 510 ITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQ 549 TE +PE +P P SPRAP + + P + SP+ + Sbjct: 465 NTEDNGKPE---KPEPSSPSPRAPAS-SQHPSVPASPQGR 500 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 60.1 bits (144), Expect = 1e-08 Identities = 121/563 (21%), Positives = 198/563 (35%), Gaps = 87/563 (15%) Query: 180 KNKDSGSDTASAIIPSTTPSVDSDDESVV-KDKKKKSKIKTLLSKSNLQKTPLSQSMSVL 238 +N++S S ++S+ ST + S S ++ +KK K+K +K N K Sbjct: 121 ENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKD--NKKNRTKKK-------- 170 Query: 239 PTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHK-RTASTDLKQLNQVNFTLPK-- 295 PT KP V DE+ S D K T T Q N+V+ T PK Sbjct: 171 PTPKPPVV-----------------DEAGSGLDNGDFKVTTPDTSTTQHNKVS-TSPKIT 212 Query: 296 -KEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSP-SPKGFRKKH 353 + ++ L +D +++ +N E E K+++ ++ S G K Sbjct: 213 TAKPINPRPSLPPNSDTSKETSLTVN--------KETTVETKETTTTNKQTSTDGKEKTT 264 Query: 354 LFSSTENLAAGSWKEPAEGGG-LSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENM 412 T+++ S K+ A L+ +E++TK ++T P P P + Sbjct: 265 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP--ALTTPK-EPTPTTPKEPASTT 321 Query: 413 APANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKP 472 + T ++ + E ++ S T K+ A + E T P P Sbjct: 322 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 381 Query: 473 GEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPI----- 527 S P + K+ A ++ + E T E P + EP P Sbjct: 382 TTTKSAPT------TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 435 Query: 528 --------SSPRAPQTRAVKPRLEVSPE--AQPTARLPSPTDSPSSLPPLPSSSGQASVP 577 ++P+ P K +P+ A T + PSPT P P+ + S P Sbjct: 436 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT-----TPKEPAPTTTKSAP 490 Query: 578 SELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQ 637 + A T + +P+ S + +TP E P + A P PK Sbjct: 491 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-----PTTPKEPAP 545 Query: 638 TESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEK----------NTSSL 687 T P P + + K+P+ K T + + T EK T+ Sbjct: 546 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 605 Query: 688 ELEESLPEQPETGRQEEELPRFP 710 EL + PE+P EE P P Sbjct: 606 ELAPTTPEEPTPTTPEEPAPTTP 628 Score = 46.6 bits (109), Expect = 2e-04 Identities = 78/385 (20%), Positives = 131/385 (34%), Gaps = 39/385 (10%) Query: 336 KDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTL 395 K+ +P+++ P K +T A + KEPA S+ E S + + Sbjct: 463 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 522 Query: 396 PSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENP 455 PAP PA + + A + K + ++ T K+ A + E Sbjct: 523 TPKEPAPTTP------KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 576 Query: 456 LTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEA 515 T P + L P + A E + ++ A + + E T A Sbjct: 577 PTTPKK-----LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 631 Query: 516 EPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQAS 575 P + EP P ++P+ P A T + P+PT + P P + + Sbjct: 632 APNTPKEPAP--TTPKEP--------------APTTPKEPAPTTPKETAPTTP----KGT 671 Query: 576 VPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAE 635 P+ L A T + + P+ + P ST T + P +G A P PK Sbjct: 672 APTTLKEPAPT-TPKKPAPKELAPTTTKEPTST-TCDKPAPTTPKGTA-----PTTPKEP 724 Query: 636 LQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPE 695 T P P + + K+P+ K + T G TS + + P+ Sbjct: 725 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPK 783 Query: 696 QPETGRQEEELPRFPCKKQDYSPSS 720 + +E P P K +P + Sbjct: 784 ETAPTTPKEPAPTTPKKPAPTTPET 808 Score = 46.2 bits (108), Expect = 2e-04 Identities = 95/494 (19%), Positives = 161/494 (32%), Gaps = 66/494 (13%) Query: 239 PTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEG 298 P K K ++ + + +N++ SSS+S S + + N L KK Sbjct: 99 PNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKK-- 156 Query: 299 LSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSST 358 L+ K++ +R+ ++P K + D + S Sbjct: 157 ------LKVKDNKKNRTK----------KKPTPKPPVVDEAGSG---------------- 184 Query: 359 ENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPA-PLVSGDLRENMAPANS 417 L G +K +S Q ++ ST + + + RP+ P S +E N Sbjct: 185 --LDNGDFKVTTPD---TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNK 239 Query: 418 EATKEAKES------------KKPESRRSSLLSLMTGKKDVAKGSEG-ENPLTVPGREKE 464 E T E KE+ +K S + + T KD+A S+ P + Sbjct: 240 ETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK 299 Query: 465 GMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPR 524 G + + P E ++ T + S+ ++ T ++ P + EP Sbjct: 300 GPALTTPKEPTPTTPKEPASTTPKEPTPTTIK---SAPTTPKEPAPTTTKSAPTTPKEPA 356 Query: 525 PPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGA 584 P + AP T +P + E PT +PT P P P+ A Sbjct: 357 PTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA----PTTPKEPA 411 Query: 585 DTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPV 644 T E +P + +TP E P + A P PK T P Sbjct: 412 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA-----PTTPKEPAPTTPKEPA 466 Query: 645 PNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEE 704 P + + K+P+ K + T T+ E + ++P +E Sbjct: 467 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 526 Query: 705 ELPRFPCKKQDYSP 718 P P K +P Sbjct: 527 PAPTTPKKPAPTTP 540 Score = 33.9 bits (76), Expect = 1.0 Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%) Query: 1028 CDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEE-KPMGNGSPSPP 1086 CD Q + P ++ +H P SS K+ P PSG + K SP PP Sbjct: 43 CDCDAQCKKYDKCCPDYESFCAEVHNPTSPPSS---KKAPPPSGASQTIKSTTKRSPKPP 99 Query: 1087 PGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGR 1138 + S +E V+ + SS+ S + +S+ + K++ +A R Sbjct: 100 NKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANR 151 Score = 33.5 bits (75), Expect = 1.3 Identities = 150/785 (19%), Positives = 259/785 (32%), Gaps = 88/785 (11%) Query: 376 SSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSS 435 SS + S ++KS T S +P + + E T+E S+ ES SS Sbjct: 74 SSKKAPPPSGASQTIKSTTKRSPKPP----NKKKTKKVIESEEITEEHSVSENQESSSSS 129 Query: 436 LLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVV 495 S + + K +N + RE + L VK + ++ ++ VV Sbjct: 130 --SSSSSSSTIRKIKSSKN--SAANRELQKKLK-VKDNK------KNRTKKKPTPKPPVV 178 Query: 496 SRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLP 555 GS L+ D ++T P+ S ++ +SP+ + + PR + P + T++ Sbjct: 179 DEAGSGLDN-GDFKVTTPDT---STTQHNKVSTSPKITTAKPINPRPSLPPNSD-TSKET 233 Query: 556 SPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPIST--STPIE 613 S T + + ++ S G T + E+ S+ S+ AP S + P Sbjct: 234 SLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI-EKTSAKDLAPTSKVLAKPTP 292 Query: 614 SWPLVDRGQAKS---EGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDS 670 +G A + E P PK T P P + + S P PA T+ + Sbjct: 293 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP----TTIKSAPTTPKEPAPTTTKSA 348 Query: 671 -LMGRTRETGTEKNTSSLELEESLPEQ-----PETGRQEEELPRFPCKKQDYSPSSGEAQ 724 + T K + +E P P T + P+ P P+ + Sbjct: 349 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 408 Query: 725 EVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPM--GASVP 782 E P + +P + A + + A A ++ AP P + P Sbjct: 409 E-PAPTTPKEPTPTTPKEPAPT-----TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP 462 Query: 783 SIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAW 842 + E ++ T K S T+E A + + P+E +P Sbjct: 463 KEPAPTTTKEPSPTTPKEPAPTTTK----SAPTTTKEP---APTTTKSAPTTPKEPSPTT 515 Query: 843 SVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLL-PSQEESFSEVPMSE 901 + + P+ P ++ + TTP P PA P+ P + Sbjct: 516 TKEPAPTT---PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 572 Query: 902 ASSAKDTP--LFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSL 959 +A TP L E T + A L+ + + + P + Sbjct: 573 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 632 Query: 960 PSIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEAD 1019 P+ P+ + + + + T G L P P K P Sbjct: 633 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP----- 687 Query: 1020 RLVLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPH----LGKSSSLDKQLPGPSGGEEE 1075 AP+ +++ T KP G + + K+ P P+ +E Sbjct: 688 --------------APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE-PAPTTPKEP 732 Query: 1076 KPMGNGSPSPPPGTSLDNPVPS----PSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKAT 1131 P +P T+L P P+ P+P E+ P T P+S SD +T + T Sbjct: 733 APT---TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 789 Query: 1132 AEGSA 1136 + A Sbjct: 790 PKEPA 794 Score = 32.3 bits (72), Expect = 3.0 Identities = 49/253 (19%), Positives = 87/253 (34%), Gaps = 23/253 (9%) Query: 489 KDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP--RLEVSP 546 K+ A ++ +S + T E P + EP P AP T P EVS Sbjct: 759 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 818 Query: 547 EA---QPTARLPSPTDSPSSLPPLPSSSGQASVPSELG-HGADTQSSESPSVFSSLSSPI 602 +PT SP +S L P+ + P E G T ++ P + ++ Sbjct: 819 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 878 Query: 603 AAPISTSTP--IESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGS-----SVLGSL 655 +TP + P + + A + K T +T + + L + Sbjct: 879 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 938 Query: 656 FKQPSFPANKGT----------EDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEE 705 P K T E++ + R T ++ T + P++P + ++ + Sbjct: 939 TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT 998 Query: 706 LPRFPCKKQDYSP 718 +PR K +P Sbjct: 999 MPRVRKPKTTPTP 1011 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 60.1 bits (144), Expect = 1e-08 Identities = 121/563 (21%), Positives = 198/563 (35%), Gaps = 87/563 (15%) Query: 180 KNKDSGSDTASAIIPSTTPSVDSDDESVV-KDKKKKSKIKTLLSKSNLQKTPLSQSMSVL 238 +N++S S ++S+ ST + S S ++ +KK K+K +K N K Sbjct: 162 ENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKD--NKKNRTKKK-------- 211 Query: 239 PTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHK-RTASTDLKQLNQVNFTLPK-- 295 PT KP V DE+ S D K T T Q N+V+ T PK Sbjct: 212 PTPKPPVV-----------------DEAGSGLDNGDFKVTTPDTSTTQHNKVS-TSPKIT 253 Query: 296 -KEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSP-SPKGFRKKH 353 + ++ L +D +++ +N E E K+++ ++ S G K Sbjct: 254 TAKPINPRPSLPPNSDTSKETSLTVN--------KETTVETKETTTTNKQTSTDGKEKTT 305 Query: 354 LFSSTENLAAGSWKEPAEGGG-LSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENM 412 T+++ S K+ A L+ +E++TK ++T P P P + Sbjct: 306 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP--ALTTPK-EPTPTTPKEPASTT 362 Query: 413 APANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKP 472 + T ++ + E ++ S T K+ A + E T P P Sbjct: 363 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 422 Query: 473 GEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPI----- 527 S P + K+ A ++ + E T E P + EP P Sbjct: 423 TTTKSAPT------TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 476 Query: 528 --------SSPRAPQTRAVKPRLEVSPE--AQPTARLPSPTDSPSSLPPLPSSSGQASVP 577 ++P+ P K +P+ A T + PSPT P P+ + S P Sbjct: 477 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT-----TPKEPAPTTTKSAP 531 Query: 578 SELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQ 637 + A T + +P+ S + +TP E P + A P PK Sbjct: 532 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-----PTTPKEPAP 586 Query: 638 TESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEK----------NTSSL 687 T P P + + K+P+ K T + + T EK T+ Sbjct: 587 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 646 Query: 688 ELEESLPEQPETGRQEEELPRFP 710 EL + PE+P EE P P Sbjct: 647 ELAPTTPEEPTPTTPEEPAPTTP 669 Score = 46.6 bits (109), Expect = 2e-04 Identities = 78/385 (20%), Positives = 131/385 (34%), Gaps = 39/385 (10%) Query: 336 KDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTL 395 K+ +P+++ P K +T A + KEPA S+ E S + + Sbjct: 504 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 563 Query: 396 PSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENP 455 PAP PA + + A + K + ++ T K+ A + E Sbjct: 564 TPKEPAPTTP------KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 617 Query: 456 LTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEA 515 T P + L P + A E + ++ A + + E T A Sbjct: 618 PTTPKK-----LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 672 Query: 516 EPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQAS 575 P + EP P ++P+ P A T + P+PT + P P + + Sbjct: 673 APNTPKEPAP--TTPKEP--------------APTTPKEPAPTTPKETAPTTP----KGT 712 Query: 576 VPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAE 635 P+ L A T + + P+ + P ST T + P +G A P PK Sbjct: 713 APTTLKEPAPT-TPKKPAPKELAPTTTKEPTST-TCDKPAPTTPKGTA-----PTTPKEP 765 Query: 636 LQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPE 695 T P P + + K+P+ K + T G TS + + P+ Sbjct: 766 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPK 824 Query: 696 QPETGRQEEELPRFPCKKQDYSPSS 720 + +E P P K +P + Sbjct: 825 ETAPTTPKEPAPTTPKKPAPTTPET 849 Score = 46.2 bits (108), Expect = 2e-04 Identities = 95/494 (19%), Positives = 161/494 (32%), Gaps = 66/494 (13%) Query: 239 PTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEG 298 P K K ++ + + +N++ SSS+S S + + N L KK Sbjct: 140 PNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKK-- 197 Query: 299 LSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSST 358 L+ K++ +R+ ++P K + D + S Sbjct: 198 ------LKVKDNKKNRTK----------KKPTPKPPVVDEAGSG---------------- 225 Query: 359 ENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPA-PLVSGDLRENMAPANS 417 L G +K +S Q ++ ST + + + RP+ P S +E N Sbjct: 226 --LDNGDFKVTTPD---TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNK 280 Query: 418 EATKEAKES------------KKPESRRSSLLSLMTGKKDVAKGSEG-ENPLTVPGREKE 464 E T E KE+ +K S + + T KD+A S+ P + Sbjct: 281 ETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK 340 Query: 465 GMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPR 524 G + + P E ++ T + S+ ++ T ++ P + EP Sbjct: 341 GPALTTPKEPTPTTPKEPASTTPKEPTPTTIK---SAPTTPKEPAPTTTKSAPTTPKEPA 397 Query: 525 PPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGA 584 P + AP T +P + E PT +PT P P P+ A Sbjct: 398 PTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA----PTTPKEPA 452 Query: 585 DTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPV 644 T E +P + +TP E P + A P PK T P Sbjct: 453 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA-----PTTPKEPAPTTPKEPA 507 Query: 645 PNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEE 704 P + + K+P+ K + T T+ E + ++P +E Sbjct: 508 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 567 Query: 705 ELPRFPCKKQDYSP 718 P P K +P Sbjct: 568 PAPTTPKKPAPTTP 581 Score = 33.9 bits (76), Expect = 1.0 Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%) Query: 1028 CDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEE-KPMGNGSPSPP 1086 CD Q + P ++ +H P SS K+ P PSG + K SP PP Sbjct: 84 CDCDAQCKKYDKCCPDYESFCAEVHNPTSPPSS---KKAPPPSGASQTIKSTTKRSPKPP 140 Query: 1087 PGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGR 1138 + S +E V+ + SS+ S + +S+ + K++ +A R Sbjct: 141 NKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANR 192 Score = 33.5 bits (75), Expect = 1.3 Identities = 150/785 (19%), Positives = 259/785 (32%), Gaps = 88/785 (11%) Query: 376 SSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSS 435 SS + S ++KS T S +P + + E T+E S+ ES SS Sbjct: 115 SSKKAPPPSGASQTIKSTTKRSPKPP----NKKKTKKVIESEEITEEHSVSENQESSSSS 170 Query: 436 LLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVV 495 S + + K +N + RE + L VK + ++ ++ VV Sbjct: 171 --SSSSSSSTIRKIKSSKN--SAANRELQKKLK-VKDNK------KNRTKKKPTPKPPVV 219 Query: 496 SRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLP 555 GS L+ D ++T P+ S ++ +SP+ + + PR + P + T++ Sbjct: 220 DEAGSGLDN-GDFKVTTPDT---STTQHNKVSTSPKITTAKPINPRPSLPPNSD-TSKET 274 Query: 556 SPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPIST--STPIE 613 S T + + ++ S G T + E+ S+ S+ AP S + P Sbjct: 275 SLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI-EKTSAKDLAPTSKVLAKPTP 333 Query: 614 SWPLVDRGQAKS---EGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDS 670 +G A + E P PK T P P + + S P PA T+ + Sbjct: 334 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP----TTIKSAPTTPKEPAPTTTKSA 389 Query: 671 -LMGRTRETGTEKNTSSLELEESLPEQ-----PETGRQEEELPRFPCKKQDYSPSSGEAQ 724 + T K + +E P P T + P+ P P+ + Sbjct: 390 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 449 Query: 725 EVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPM--GASVP 782 E P + +P + A + + A A ++ AP P + P Sbjct: 450 E-PAPTTPKEPTPTTPKEPAPT-----TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP 503 Query: 783 SIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAW 842 + E ++ T K S T+E A + + P+E +P Sbjct: 504 KEPAPTTTKEPSPTTPKEPAPTTTK----SAPTTTKEP---APTTTKSAPTTPKEPSPTT 556 Query: 843 SVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLL-PSQEESFSEVPMSE 901 + + P+ P ++ + TTP P PA P+ P + Sbjct: 557 TKEPAPTT---PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 613 Query: 902 ASSAKDTP--LFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSL 959 +A TP L E T + A L+ + + + P + Sbjct: 614 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 673 Query: 960 PSIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEAD 1019 P+ P+ + + + + T G L P P K P Sbjct: 674 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP----- 728 Query: 1020 RLVLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPH----LGKSSSLDKQLPGPSGGEEE 1075 AP+ +++ T KP G + + K+ P P+ +E Sbjct: 729 --------------APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE-PAPTTPKEP 773 Query: 1076 KPMGNGSPSPPPGTSLDNPVPS----PSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKAT 1131 P +P T+L P P+ P+P E+ P T P+S SD +T + T Sbjct: 774 APT---TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 830 Query: 1132 AEGSA 1136 + A Sbjct: 831 PKEPA 835 Score = 32.3 bits (72), Expect = 3.0 Identities = 49/253 (19%), Positives = 87/253 (34%), Gaps = 23/253 (9%) Query: 489 KDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP--RLEVSP 546 K+ A ++ +S + T E P + EP P AP T P EVS Sbjct: 800 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 859 Query: 547 EA---QPTARLPSPTDSPSSLPPLPSSSGQASVPSELG-HGADTQSSESPSVFSSLSSPI 602 +PT SP +S L P+ + P E G T ++ P + ++ Sbjct: 860 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 919 Query: 603 AAPISTSTP--IESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGS-----SVLGSL 655 +TP + P + + A + K T +T + + L + Sbjct: 920 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 979 Query: 656 FKQPSFPANKGT----------EDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEE 705 P K T E++ + R T ++ T + P++P + ++ + Sbjct: 980 TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT 1039 Query: 706 LPRFPCKKQDYSP 718 +PR K +P Sbjct: 1040 MPRVRKPKTTPTP 1052 >gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sapiens] Length = 699 Score = 60.1 bits (144), Expect = 1e-08 Identities = 113/547 (20%), Positives = 194/547 (35%), Gaps = 58/547 (10%) Query: 402 PLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGR 461 PLV G LR+N + +A + + ++ SSLL + + AK E + P Sbjct: 16 PLVLGFLRDNQLSEVANKFAKATGATQQDANASSLLDIYSFWLKSAKVPERKLQANGPVA 75 Query: 462 EKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQG-----SSLNLFEDVQITEPEAE 516 +K ED+S E++ K A R G ++ E E + Sbjct: 76 KKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDD 135 Query: 517 PESKSEPRPPISSPRAPQTRAVK--PRLEVS-------------PEAQPTARLPSPTDSP 561 + + + + P+ PQ +A K P+ S P+ Q P + Sbjct: 136 DDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQ 195 Query: 562 SSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPIST--------STPIE 613 + PP P+ + + + + SS S S S A P T P++ Sbjct: 196 TKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVK 255 Query: 614 SWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQP-----SFPANKGTE 668 + R + SE + E Q + + P SSV P + P K E Sbjct: 256 AATTPTRKSSSSEDSS-SDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVE 314 Query: 669 DSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPF 728 + E ++++ SS E E+ P + + + P P KK S S + Sbjct: 315 KQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPP--PAKKAAESSSDSSDSD--- 369 Query: 729 ALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMM 788 SS+ +P AG ++ ++ +S A A AP P+G + Sbjct: 370 ----SSEDDEAP--SKPAGTTKNSSNKPAVTTKSPAVKPA--AAPKQPVGGGQKLLTRKA 421 Query: 789 RKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNA 848 + +++KTKK V+ ++ +A A AAL S P + P S ++ Sbjct: 422 DSSSSEEESSSSEEEKTKKMVATTK----PKATAKAAL------SLPAKQAPQGS-RDSS 470 Query: 849 SDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDT 908 SD + S E+ +S P A+P+ + S S+ SS ++ Sbjct: 471 SDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEE 530 Query: 909 PLFRMEG 915 + +G Sbjct: 531 EKLKGKG 537 Score = 44.3 bits (103), Expect = 8e-04 Identities = 66/273 (24%), Positives = 112/273 (41%), Gaps = 40/273 (14%) Query: 199 SVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPTSKP-------EKVLLRPG 251 S DS D +D + SK S+ + ++S +V P + P +K+L R Sbjct: 362 SSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKA 421 Query: 252 DFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDV 311 D S +E+ESSS+ + + K A+T K + +LP K+ G S +D Sbjct: 422 DSSS------SEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQ--GSRDSSSDS 473 Query: 312 LSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAE 371 S S+ E+ E K +S + K +K + + A + K AE Sbjct: 474 DSSSS----------EEEEEK--------TSKSAVKKKPQKVAGGAAPSKPASAKKGKAE 515 Query: 372 GGGLSSDRQLSESSTKDSLKSMTLPSYRP-APLVSGDLRENMAPANSEATKEAKESKKPE 430 SS SE ++ LK P RP AP +G + N +A K ++E ++ E Sbjct: 516 SSNSSSSDDSSEEE-EEKLKGKGSP--RPQAPKANG--TSALTAQNGKAAKNSEEEEE-E 569 Query: 431 SRRSSLLSLMTGKKDVAKGSEGENPLTVPGREK 463 ++++++ +G K +E P +K Sbjct: 570 KKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKK 602 Score = 40.0 bits (92), Expect = 0.014 Identities = 90/505 (17%), Positives = 173/505 (34%), Gaps = 50/505 (9%) Query: 125 WYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGKNKDS 184 W K P +K + G + + + ++ D S +++ K + K Sbjct: 57 WLKSAKVPERKLQANGPVAKKAK--KKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGL 114 Query: 185 GSDTASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPL---------SQSM 235 A+A ++ S +S D+ +D+KK+ K + ++ K P S S Sbjct: 115 PPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSS 174 Query: 236 SVLPTSKPEKVLLRPGDFQSQWD------------------EDDNEDESSSASDVMSHKR 277 S K +K + P ++Q + SSS+SD ++ Sbjct: 175 SEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEK 234 Query: 278 TASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKD 337 A+T K T+PKK+ ++ +++ +S+ + + E+ + + K Sbjct: 235 AAATPKK-------TVPKKQVVA-KAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKP 286 Query: 338 SSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPS 397 SS P P K + A ++P E SSD S+SS+++ K T Sbjct: 287 GPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDE--SDSSSEEEKKPPTKAV 344 Query: 398 YRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLT 457 A ++ ++ + ++ E + S+ + + K V S P Sbjct: 345 VSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAA 404 Query: 458 VPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEP 517 P + G + D+S E+ E+ T +V+ + + +A Sbjct: 405 APKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQ 464 Query: 518 ESK-SEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASV 576 S+ S SS + + K ++ P+ PS P+S+ + Sbjct: 465 GSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSK----------PASAKKGKA 514 Query: 577 PSELGHGADTQSSESPSVFSSLSSP 601 S +D S E SP Sbjct: 515 ESSNSSSSDDSSEEEEEKLKGKGSP 539 Score = 30.8 bits (68), Expect = 8.7 Identities = 38/148 (25%), Positives = 59/148 (39%), Gaps = 44/148 (29%) Query: 1033 QAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGS---------P 1083 +AP + T P+ +++ + SS D++ E++KPM N Sbjct: 251 KAPVKAATTPTRKSSS--------SEDSSSDEE------EEQKKPMKNKPGPYSSVPPPS 296 Query: 1084 SPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFG 1143 +PPP SL P + + PV S SS SD S++E +K Sbjct: 297 APPPKKSLGTQPPKKAVEKQQPVESSEDSSDESD----SSSEEEK--------------- 337 Query: 1144 KRKPLLQAWVSPSETHPVSAQPGAGTGS 1171 KP +A VS + T P A+ A + S Sbjct: 338 --KPPTKAVVSKATTKPPPAKKAAESSS 363 >gi|149773456 hypothetical protein LOC643314 [Homo sapiens] Length = 1427 Score = 59.3 bits (142), Expect = 2e-08 Identities = 107/488 (21%), Positives = 172/488 (35%), Gaps = 64/488 (13%) Query: 456 LTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEA 515 +TV E + V E+ + + + A S + ++L + V ITE + Sbjct: 912 VTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAI--TVPITEEDG 969 Query: 516 EPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTD--SPSSLPPLPS--SS 571 PE P + +P P T AV+ P A P A +P+P + SP++ P P +S Sbjct: 970 TPEGPVTPATTVHAPEEPDTAAVRVSTPEEP-ASPAAAVPTPEEPTSPAAAVPTPEEPTS 1028 Query: 572 GQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLL 631 A+VP + + +P +S ++ + P ++P + P + + + P Sbjct: 1029 PAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP-T 1087 Query: 632 PKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEE 691 P+ + P P ++P+ PA T + +S Sbjct: 1088 PEEPTSPAAAVPTP-----------EEPTSPA------------AAVPTPEEPASPAAAV 1124 Query: 692 SLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRD 751 PE+P + P P P+ E+ A+ + A SP AA Sbjct: 1125 PTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESA-SP----AAAVPTP 1179 Query: 752 LESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEM---GLNLRKDQKKTKKR 808 ES + + V + + P ASVP+ +M+ LEE ++ ++ Sbjct: 1180 AESASFAAVVATLEE-------PTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLA 1232 Query: 809 VSFSEQLFTEEAVAGAALLVEGHSSCPQELNP--AWSVAGNASDGEPPESPHAEDSERES 866 + S A L E SS L P S A + E P SP A S E Sbjct: 1233 AAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEE 1292 Query: 867 VTTPGPA---------------TCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLF 911 +P A T PA PA + P +E S VP S+ D+ Sbjct: 1293 PASPAAAVPTPEVAAIPAASVPTPEVPAIPA-AAVPPMEEVSPIGVPFLGVSAHTDSVPI 1351 Query: 912 RMEGEDAL 919 EG L Sbjct: 1352 SEEGTPVL 1359 Score = 38.1 bits (87), Expect = 0.054 Identities = 41/194 (21%), Positives = 69/194 (35%), Gaps = 11/194 (5%) Query: 1034 APQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDN 1093 +P A+V P E + P + + P + E+P P P S Sbjct: 1106 SPAAAVPTPEEPAS------PAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASA 1159 Query: 1094 PVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQAWV 1153 V P+P E + P+ A S + A ++ + S V L+ + Sbjct: 1160 AVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAAS---VPTPAAMVATLEEFT 1216 Query: 1154 SPSETHPVSAQPGAGTGSAKHRLHPVKPMNATATKVANCSLGTATIISENLNNEV--MMK 1211 SP+ + P S +P + + + P P A T S A + E L++ + Sbjct: 1217 SPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPT 1276 Query: 1212 KYSPSDPAFAYAQL 1225 P+ PA A + L Sbjct: 1277 PEEPASPAAAVSNL 1290 >gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2 [Homo sapiens] Length = 1481 Score = 57.8 bits (138), Expect = 7e-08 Identities = 135/587 (22%), Positives = 214/587 (36%), Gaps = 93/587 (15%) Query: 163 KDKSR---NPFGKLKDKIKGKNKDSGSDT-----ASAIIPSTTPSVDS--DDESVVKDKK 212 K+KS+ + G +KD+I G +K S +T A S+ S S E K+++ Sbjct: 130 KEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERE 189 Query: 213 KKSKIKTLLSKSNLQKTPLSQSMSVLPTSKPEKVLLRPGDFQSQ----------WDEDDN 262 KS K ++TP S P + + D Q D D + Sbjct: 190 LKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLS 249 Query: 263 EDESSSASDVMSHKRT-ASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCING 321 S ++S+ S+K++ ST +Q + + P KE ++ RS + R Sbjct: 250 PSRSHTSSNYDSYKKSPGSTSRRQ----SVSPPYKEPSAYQSSTRSPSPYSRRQ----RS 301 Query: 322 NHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHL-FSSTENLAAGSWKEPAEGGGLSSDRQ 380 Y + + E S SPSP G R+ F S +L+ S Sbjct: 302 VSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPA 361 Query: 381 LSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLM 440 S S+ S K + R + + L P NS E KK E ++ + M Sbjct: 362 YSRHSSSHSKKKRSSSRSRHSSISPVRL-----PLNSSLGAELSRKKK-ERAAAAAAAKM 415 Query: 441 TGKKDVAKGSEGENPLTVPGREK---EGMLMGVKPGE-------DASGPAEDLVR----- 485 GK+ +KGS P+ +P +E E G++ + + S P +LV Sbjct: 416 DGKE--SKGS----PVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLN 469 Query: 486 ---RSEKDTAAVVSRQGSSLNLFEDVQI-----TEPEAEPESKSEPRPPISSPRAPQTRA 537 ++ DT V + S +L +D++ ++P A E P+ +S + +T Sbjct: 470 TEVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEK--ETPP 527 Query: 538 VKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSS 597 P + P PT P T LPP+P+ Q +P S FS Sbjct: 528 PLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPPLP------------PSQPAFSQ 575 Query: 598 LSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFK 657 + + + + ST S QA S+ PP+ + Q +P+ +S L L Sbjct: 576 VPASSTSTLPPST--HSKTSAVSSQANSQ-PPVQVSVKTQVSVTAAIPHLKTSTLPPLPL 632 Query: 658 QPSFPANKGTEDSLMGRTRET------GTEKNTSSLELEESLPEQPE 698 P P D M +ET EK + L LP PE Sbjct: 633 PPLLPG-----DDDMDSPKETLPSKPVKKEKEQRTRHLLTDLPLPPE 674 >gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1 [Homo sapiens] Length = 1490 Score = 57.8 bits (138), Expect = 7e-08 Identities = 135/587 (22%), Positives = 214/587 (36%), Gaps = 93/587 (15%) Query: 163 KDKSR---NPFGKLKDKIKGKNKDSGSDT-----ASAIIPSTTPSVDS--DDESVVKDKK 212 K+KS+ + G +KD+I G +K S +T A S+ S S E K+++ Sbjct: 130 KEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERE 189 Query: 213 KKSKIKTLLSKSNLQKTPLSQSMSVLPTSKPEKVLLRPGDFQSQ----------WDEDDN 262 KS K ++TP S P + + D Q D D + Sbjct: 190 LKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLS 249 Query: 263 EDESSSASDVMSHKRT-ASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCING 321 S ++S+ S+K++ ST +Q + + P KE ++ RS + R Sbjct: 250 PSRSHTSSNYDSYKKSPGSTSRRQ----SVSPPYKEPSAYQSSTRSPSPYSRRQ----RS 301 Query: 322 NHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHL-FSSTENLAAGSWKEPAEGGGLSSDRQ 380 Y + + E S SPSP G R+ F S +L+ S Sbjct: 302 VSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPA 361 Query: 381 LSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLM 440 S S+ S K + R + + L P NS E KK E ++ + M Sbjct: 362 YSRHSSSHSKKKRSSSRSRHSSISPVRL-----PLNSSLGAELSRKKK-ERAAAAAAAKM 415 Query: 441 TGKKDVAKGSEGENPLTVPGREK---EGMLMGVKPGE-------DASGPAEDLVR----- 485 GK+ +KGS P+ +P +E E G++ + + S P +LV Sbjct: 416 DGKE--SKGS----PVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLN 469 Query: 486 ---RSEKDTAAVVSRQGSSLNLFEDVQI-----TEPEAEPESKSEPRPPISSPRAPQTRA 537 ++ DT V + S +L +D++ ++P A E P+ +S + +T Sbjct: 470 TEVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEK--ETPP 527 Query: 538 VKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSS 597 P + P PT P T LPP+P+ Q +P S FS Sbjct: 528 PLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPPLP------------PSQPAFSQ 575 Query: 598 LSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFK 657 + + + + ST S QA S+ PP+ + Q +P+ +S L L Sbjct: 576 VPASSTSTLPPST--HSKTSAVSSQANSQ-PPVQVSVKTQVSVTAAIPHLKTSTLPPLPL 632 Query: 658 QPSFPANKGTEDSLMGRTRET------GTEKNTSSLELEESLPEQPE 698 P P D M +ET EK + L LP PE Sbjct: 633 PPLLPG-----DDDMDSPKETLPSKPVKKEKEQRTRHLLTDLPLPPE 674 Score = 33.9 bits (76), Expect = 1.0 Identities = 56/254 (22%), Positives = 91/254 (35%), Gaps = 36/254 (14%) Query: 514 EAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQ 573 E + S P+ P +P PQ A + P P R P P P PP P G Sbjct: 1229 ENNSDKNSGPQGPRRTPTMPQEEAAACPPHILP---PEKRPPEPPGPPPPPPPPPLVEGD 1285 Query: 574 -ASVPSELGHGADTQSSESPSVFSSLSSPIAAP-------ISTSTPIE--SWPLVDRGQA 623 +S P EL + + ++ LS P A P P+E + P +R Sbjct: 1286 LSSAPQEL------NPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYG 1339 Query: 624 KSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKN 683 ++GP A + T+ P S++ +L K +F + + E+ + + Sbjct: 1340 NTDGPETGFSA-IDTDERNSGPALTESLVQTLVKNRTFSGS-------LSHLGESSSYQG 1391 Query: 684 TSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGE 743 T S++ P + L P Q + + G + V + ++ + GE Sbjct: 1392 TGSVQ----FPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSV-----VHAETKLQNYGE 1442 Query: 744 LAAGGDRDLESQAG 757 L G S AG Sbjct: 1443 LGPGTTGASSSGAG 1456 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 57.4 bits (137), Expect = 9e-08 Identities = 185/887 (20%), Positives = 305/887 (34%), Gaps = 143/887 (16%) Query: 384 SSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGK 443 S T L SM + A +G L ++ T K S P + ++ + T Sbjct: 2806 SETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTA- 2864 Query: 444 KDVAKGSEGENPLT------VPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSR 497 SEG LT P E + P D S P S T A Sbjct: 2865 ------SEGSTLLTSIPVSTTPVASSEASTLSTTP-VDTSIPVTTSTEGSSSPTTA---- 2913 Query: 498 QGSSLNLFEDVQITEP------EAEPESKSEPRPPISSP---RAPQTRAVKPRLEVSPEA 548 +G+S+ + +++ P P + SE ++P R P T + + SP Sbjct: 2914 EGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEA--SSSPTT 2971 Query: 549 QPTARLPSPTDSPSSLP-------PLPSSSGQASVPSELGHGADT------QSSESPSVF 595 +P T P +P +S +AS S T ++S SP+ Sbjct: 2972 AEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTA 3031 Query: 596 SSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSL 655 PI+ P STP+ S P+ S P +P+A T S TPV ++ V + Sbjct: 3032 EGTGIPISTPSEGSTPLTSIPV-------STTPVAIPEAS--TLSTTPVDSNSPVVTSTE 3082 Query: 656 FKQPSFPANKGTEDSLM----GRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPC 711 PA +GT + G T TG +T+ P T L P Sbjct: 3083 VSSSPTPA-EGTSMPISTYSEGSTPLTGVPVSTT-----------PVTSSAISTLSTTPV 3130 Query: 712 KKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEV 771 +S EA P +S+G P + G +++ + D+ Sbjct: 3131 DTSTPVTTSTEAHSSP----TTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSA 3186 Query: 772 AP---PLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLV 828 P P+ S + S + + + + V S T A + A++L Sbjct: 3187 TPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSN---TPVASSEASIL- 3242 Query: 829 EGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLP 888 S+ P + N + + AS P +E S+ T P+ P L Sbjct: 3243 ---STTPVDSNTPLTTSTEASSSPPT-------AEGTSMPTSTPSEGSTP--------LT 3284 Query: 889 SQEESFSEVPMSEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFK 948 S S + V SE S+ TP VT Y S+AS + S+ Sbjct: 3285 SMPVSTTTVASSETSTLSTTPA----DTSTPVTTY-SQASSSPPIADGTSMPTSTYSEGS 3339 Query: 949 SPIMADLNLSLPSIPEVASDDERIDQVE-DDGDQVEDDGETAKSSTLDIGALSLGLVVPC 1007 +P+ N+S + P V+S+ + D V E + S T + G +P Sbjct: 3340 TPLT---NMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTT-----AEGTSIPT 3391 Query: 1008 PERGKGPSGEADRLVLGEGLCDFRLQAPQAS-------VTAPSEQTTEFGIHKPHLGKSS 1060 +G + A V + + + VT +E ++ P + + + Sbjct: 3392 SSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSS-----PTIAEGT 3446 Query: 1061 SLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLD------NPVPSPSPSEIFPVTHSFPSSA 1114 SL P + E P+ S P S + PV + +P T+S P++A Sbjct: 3447 SL----PTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTA 3502 Query: 1115 HSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPGAGTGSAKH 1174 + TSTA EGS P+ + S T PV + T S++ Sbjct: 3503 EVTSMPTSTA-------GEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFV-TSSSQA 3554 Query: 1175 RLHPVKPMNATATKVANCSLGTATIISENLNNEVM--MKKYSPSDPA 1219 P + T +++ S G++++ + L++ + + +PS P+ Sbjct: 3555 SSSPA-TLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPS 3600 Score = 48.5 bits (114), Expect = 4e-05 Identities = 158/837 (18%), Positives = 287/837 (34%), Gaps = 95/837 (11%) Query: 370 AEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKP 429 AEG + + SE ST L+SM + + A + L + T + S P Sbjct: 2559 AEGTSMPTSTY-SEGSTP--LRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSP 2615 Query: 430 ESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEK 489 + + + + + T +V+ T+P E + P + + LV S Sbjct: 2616 TTAKDTSMPIST-PSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRT-----LVTTSTG 2669 Query: 490 DTAAVVSRQGSSLNLFEDVQITEPE----------AEPESKSEPRPPISSPRAPQTRAVK 539 +++ + +GSS+ + + P A E+ + P+ + P T + + Sbjct: 2670 TSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTS-TPVTTSAE 2728 Query: 540 PRLEVSPEAQPTARLPSPTDSPSSLPP-----LPSSSGQAS------VPSELGHGADTQS 588 + + R+ +P+D + L LP +S +AS V + + T++ Sbjct: 2729 ASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEA 2788 Query: 589 SESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPL-LPKAELQTESLTPVPNS 647 S SP+ S P + P TSTP+ S P+ A SE L + T T S Sbjct: 2789 SSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKAS 2848 Query: 648 GSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELP 707 S P A++G+ T T +T+ + E+ T + +P Sbjct: 2849 SSPTTAEGIVVPISTASEGS-------TLLTSIPVSTTPVASSEA--STLSTTPVDTSIP 2899 Query: 708 RFPCKKQDYSPSSGEAQEVPFALSLSSDGAVS-PVGELAAGGDRDLESQAGSLVESKARD 766 + SP++ E +P +S+ VS P+ + S+A +L + D Sbjct: 2900 VTTSTEGSSSPTTAEGTSMP----ISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPV-D 2954 Query: 767 AAEEVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAG--A 824 V +S + + + G ++R + + VA A Sbjct: 2955 TRTPVTTSAEASSSPTTAEGTSMPISTPG----------ERRTPLTSMSVSTMPVASSEA 3004 Query: 825 ALLVEGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADH 884 + L + + + + + + E P + SE + T P + A P Sbjct: 3005 STLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEAS 3064 Query: 885 LLLPSQEESFSEVPMSEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLV 944 L + +S S V S S+ TP EG ++ Y ++ G+ P+S + Sbjct: 3065 TLSTTPVDSNSPVVTSTEVSSSPTP---AEGTSMPISTYSEGSTPLTGV---PVSTTPVT 3118 Query: 945 SDFKSPIMADLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLV 1004 S S + S P S + +G + + S+ L +S LV Sbjct: 3119 SSAISTL--STTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLV 3176 Query: 1005 VPCPERGKG-----------PSGEADRLVLGEGLCDFRLQAPQASVTAPSE---QTTEFG 1050 V + S EA EG P +T + T Sbjct: 3177 VSSEDSTLSATPVDTSTPVTTSTEATSSTTAEG-TSIPTSTPSEGMTPLTSVPVSNTPVA 3235 Query: 1051 IHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDNPVPS--PSPSEIFPVTH 1108 + + ++ +D P + E + SP GTS+ PS +P PV+ Sbjct: 3236 SSEASILSTTPVDSNTPLTTSTE-----ASSSPPTAEGTSMPTSTPSEGSTPLTSMPVST 3290 Query: 1109 SFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQP 1165 + +S+ + T T+ A++ T A P+ P+ T+ + P Sbjct: 3291 TTVASSETSTLSTTPADTSTPVTTYSQA------SSSPPIADGTSMPTSTYSEGSTP 3341 Score = 47.0 bits (110), Expect = 1e-04 Identities = 171/885 (19%), Positives = 289/885 (32%), Gaps = 102/885 (11%) Query: 376 SSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEA--------------TK 421 S+ S ++ + S + P R PL + L ANSEA T Sbjct: 2667 STGTSSSPTTAEGSSMPTSTPGERSTPLTN-ILVSTTLLANSEASTLSTTPVDTSTPVTT 2725 Query: 422 EAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAE 481 A+ S P + + + + T S+G PLT +L+ P + Sbjct: 2726 SAEASSSPTTAEGTSMRISTP-------SDGSTPLT-------SILVSTLP---VASSEA 2768 Query: 482 DLVRRSEKDTAAVVSRQGSSLNLFEDVQITE-PEAEPESKSEP-------RPPISSPRAP 533 V + DT+ V+ + + ++T P + P S P P++S A Sbjct: 2769 STVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAG 2828 Query: 534 QTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPS 593 T + P +P T SPT + + P+ ++S +++ + + +S S Sbjct: 2829 -TLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEAS 2887 Query: 594 VFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTE------SLTPVPNS 647 S+ + P++TST S P G + P+ +E+ T S PV S Sbjct: 2888 TLSTTPVDTSIPVTTSTEGSSSPTTAEGTSM----PISTPSEVSTPLTSILVSTVPVAGS 2943 Query: 648 GSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELP 707 +S L + P E S T E GT + S P + T + Sbjct: 2944 EASTLSTTPVDTRTPVTTSAEASSSPTTAE-GT-------SMPISTPGERRTPLTSMSVS 2995 Query: 708 RFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDA 767 P + S S + ++ S++ + SP G S+ GS + + Sbjct: 2996 TMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSE-GSTPLTSIPVS 3054 Query: 768 AEEVAPPLPMGASVPSIDSMMRKL--EEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAA 825 VA P S +DS + E+ + + + ++SE V + Sbjct: 3055 TTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVST 3114 Query: 826 LLVEGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHL 885 V + P + + E SP + +TP + P + Sbjct: 3115 TPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTM 3174 Query: 886 LLPSQEESFSEVPMSEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVS 945 L+ S E+S + S+ T A T + S+ ++ L V Sbjct: 3175 LVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTP------SEGMTPLTSVP 3228 Query: 946 DFKSPIMADLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSL---- 1001 +P+ A S+ S V S+ E +G + +ST G+ L Sbjct: 3229 VSNTPV-ASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMP 3287 Query: 1002 --GLVVPCPERGKGPSGEADRLVLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKS 1059 V E + AD P A T+ T G P S Sbjct: 3288 VSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEG-STPLTNMS 3346 Query: 1060 SSLDKQLPGPSGGEEEKPMGNGSP-------SPPPGTSLDNPVPSPSPSE------IFPV 1106 S + + P+ +P S P T+ +P+ SPSE PV Sbjct: 3347 FSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPV 3406 Query: 1107 THSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQAWVS----PSETHPVS 1162 + + S+ +T T+ +S T A + L + S P P+S Sbjct: 3407 STTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLS 3466 Query: 1163 AQPGAGTGSAKHRLHPV---------KPMNATATKVANCSLGTAT 1198 P A + ++ PV P N++ T S+ T+T Sbjct: 3467 TTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTST 3511 Score = 46.6 bits (109), Expect = 2e-04 Identities = 172/877 (19%), Positives = 278/877 (31%), Gaps = 127/877 (14%) Query: 358 TENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANS 417 T + A S AEG LS+ + S L M L + L A N Sbjct: 248 TISAQASSSPTTAEGPSLSNS---APSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNI 304 Query: 418 EATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDAS 477 + S P + + + T +EG PLT S Sbjct: 305 PVITSTEASSSPTTAEGTSIPTSTY-------TEGSTPLT-------------------S 338 Query: 478 GPAEDL-VRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEP---ESKSEPRPPISSPRAP 533 PA + V SE T ++ S+L TEP + P E+ S +S P Sbjct: 339 TPASTMPVATSEMSTLSITPVDTSTLVTTS----TEPSSLPTTAEATSMLTSTLSEGSTP 394 Query: 534 QTRA-VKPRLEVSPEAQPTARLPSPTDS----PSSLPPLPSSSGQASVPSELGHGADTQS 588 T V L S EA T+ +P + + S P+++ S+ + T Sbjct: 395 LTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPL 454 Query: 589 SESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTE--------- 639 + P + ++S A+ +ST TP++S V S PP + T Sbjct: 455 TSMPVSTTPVASSEASNLST-TPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPL 513 Query: 640 -----SLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLP 694 S PV +S +S L + S P +E S T E + ++ E L Sbjct: 514 TSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLT 573 Query: 695 EQPETGR-----QEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGD 749 P + R + P + +S EA + S +++G P + G Sbjct: 574 NMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEAS----SSSTTAEGTSMPTSTYSERGT 629 Query: 750 RDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRV 809 + S + S + +A+ P+ V + T + Sbjct: 630 T-ITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEAT------------SSSTTAEGT 676 Query: 810 SFSEQLFTEEAVAGAAL-----LVEGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSER 864 S +TE + ++ LV + P + + E SP D Sbjct: 677 SMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGAS 736 Query: 865 ESVTTPGPATCGAPASPADHLLLPSQEES-FSEVPM---------SEASSAKDT------ 908 +TP + + P LL S E S S P+ +EAS + T Sbjct: 737 MPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSM 796 Query: 909 PLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASD 968 P+ L+T + + LS + D SP+ +S P + Sbjct: 797 PISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPV--DSNSPVTTSTEVSSSPTPAEGTS 854 Query: 969 DERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLV-VPCPERGKGPSGEADRLVLGEGL 1027 E T +T I LS V P + + G + Sbjct: 855 MPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSM 914 Query: 1028 CDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPP 1087 +T+ + TT + ++ +D P + E SP+ Sbjct: 915 PTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTE-----ATSSPTTAE 969 Query: 1088 GTSLDNPVPS--PSPSEIFPVTHSFPSSAHSDTHH-----------TSTAESQKKATAEG 1134 GTS+ PS +P PV+H+ +++ + T TST S TAEG Sbjct: 970 GTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEG 1029 Query: 1135 SAGRVENFGK------RKPLLQAWVSPSETHPVSAQP 1165 ++ + R P+ V+ SET +S P Sbjct: 1030 TSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTP 1066 Score = 45.4 bits (106), Expect = 3e-04 Identities = 187/913 (20%), Positives = 309/913 (33%), Gaps = 148/913 (16%) Query: 266 SSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVY 325 SS AS + + ST + + + + EG S S+ L S I + Sbjct: 761 SSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTS---IPVSITP 817 Query: 326 LEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESS 385 + PEA ++P S SP + +STE S PAEG + + + S Sbjct: 818 VTSPEAS--TLSTTPVDSNSP-------VTTSTE---VSSSPTPAEGTSMPTS---TYSE 862 Query: 386 TKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKD 445 + L SM + + A L ++ T + P + + + T Sbjct: 863 GRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTP--- 919 Query: 446 VAKGSEGENPLT------VPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQG 499 EG PLT P E + P D S P V S + T++ + +G Sbjct: 920 ----GEGSTPLTSMPDSTTPVVSSEARTLSATP-VDTSTP----VTTSTEATSSPTTAEG 970 Query: 500 SSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTD 559 +S+ P + P SE P++S T + P T Sbjct: 971 TSI----------PTSTP---SEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTS 1017 Query: 560 SPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVD 619 + +S PP P++ G S+P+ T + P + ++S + +ST+ S P+ Sbjct: 1018 TEASSPP-PTAEG-TSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTT 1075 Query: 620 RGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETG 679 QA S G+S+ S + + S P + + + E Sbjct: 1076 YSQASSSSTTA----------------DGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEAS 1119 Query: 680 TEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVS 739 T S+ ++ S+P T + SP++ E +P S S+G + Sbjct: 1120 T---LSTTPVDTSIPVTTST-------------EASSSPTTAEGTSIP--TSPPSEGT-T 1160 Query: 740 PVGELAAGGDRDLESQAGSL----VESKARDAAEEVA---PPLPMGASVPSIDSMMRKLE 792 P+ + + S+A +L V+SK + A A PP S+P+ R Sbjct: 1161 PLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTP 1220 Query: 793 EMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGE 852 + +R T A + A+ L + + + + + E Sbjct: 1221 LTSMPVRH----------------TPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAE 1264 Query: 853 PPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLFR 912 P + SE ++ T P + SP LL + ++ V S S+ TP Sbjct: 1265 GTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTP--- 1321 Query: 913 MEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDERI 972 EG + Y EG PL+ + + + ++A +S+ S V + Sbjct: 1322 AEGTSMPTSTYS------EG--RTPLTSIPV----NTTLVASSAISILSTTPVDNSTPVT 1369 Query: 973 DQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFRL 1032 E +G + +S G L + P ++ L D Sbjct: 1370 TSTEACSSPTTSEGTSMPNSNPSEGTTPLTSI----PVSTTPVVSSEASTLSATPVDTST 1425 Query: 1033 QAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLD 1092 S A S TT GI P S+ + + P S P+ N S T Sbjct: 1426 PG-TTSAEATSSPTTAEGISIP---TSTPSEGKTPLKSIPVSNTPVANSEAS----TLST 1477 Query: 1093 NPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQAW 1152 PV S SP VT + SS+ + TS A S +EGS P+ Sbjct: 1478 TPVDSNSP----VVTSTAVSSSPTPAEGTSIAIS---TPSEGSTALTS-----IPVSTTT 1525 Query: 1153 VSPSETHPVSAQP 1165 V+ SE + +S P Sbjct: 1526 VASSEINSLSTTP 1538 Score = 44.3 bits (103), Expect = 8e-04 Identities = 86/386 (22%), Positives = 121/386 (31%), Gaps = 68/386 (17%) Query: 358 TENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANS 417 T + A S AEG G+ S+ S+ T P P + L +NS Sbjct: 3019 TTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPE---ASTLSTTPVDSNS 3075 Query: 418 EATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLT------VPGREKEGMLMGVK 471 + S P + + + T SEG PLT P + Sbjct: 3076 PVVTSTEVSSSPTPAEGTSMPISTY-------SEGSTPLTGVPVSTTPVTSSAISTLSTT 3128 Query: 472 PGEDASGPAEDLVRRSEKDTAAVVSR------QGSSLNLFEDVQITEPEAEPESKSEPRP 525 P + ++ S T+ S +GS+ + V + +S P Sbjct: 3129 PVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATP 3188 Query: 526 -PISSPRAPQTRAVKPRLEVS---PEAQPTARLPSPTDSPSSLPPLPSSSGQ----ASVP 577 S+P T A P + P+ + T P S P+ SS V Sbjct: 3189 VDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVD 3248 Query: 578 SELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSE----------- 626 S T++S SP S P + P STP+ S P+ A SE Sbjct: 3249 SNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADT 3308 Query: 627 ------------GPPLLPKAELQTE--------------SLTPVPNSGSSVLGSLFKQPS 660 PP+ + T S TPV +S +S L + S Sbjct: 3309 STPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTS 3368 Query: 661 FPANKGTEDSLMGRTRETGTEKNTSS 686 P TE SL T E GT TSS Sbjct: 3369 TPVTTSTEASLSPTTAE-GTSIPTSS 3393 Score = 42.4 bits (98), Expect = 0.003 Identities = 149/723 (20%), Positives = 236/723 (32%), Gaps = 74/723 (10%) Query: 511 TEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSS 570 TE ES S+ S + P P + P+ S T + S PLPS Sbjct: 113 TESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSF 172 Query: 571 SGQASVPSELGHGA----DTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSE 626 S+ ++ TQ+S SP+ S + P + STP+ S P A SE Sbjct: 173 EAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSE 232 Query: 627 GPPLL-PKAELQT-------ESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRET 678 LL E+ T S +P G S+ S S P + ++ + E Sbjct: 233 AITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEA 292 Query: 679 GTEKNTSSLE----LEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSS 734 T T + + + T + +P + +S A +P A S S Sbjct: 293 STLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMS 352 Query: 735 DGAVSPV--GELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLE 792 +++PV L + S E + PL ++P ++ E Sbjct: 353 TLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPL---TNMPVSTILVASSE 409 Query: 793 EMGLNLRKDQKK---TKKRVSFSEQLFTEEAVAGAALLVEGH---SSCPQELNP-AWSVA 845 + K T + S E+ + EG +S P P A S A Sbjct: 410 ASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEA 469 Query: 846 GNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPM--SEAS 903 N S S S + P P S P S S +P+ SEAS Sbjct: 470 SNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEAS 529 Query: 904 SAKDTPLFRMEGEDALVTQYQSKASD-------------HEG---LLSDPLSDLQLVS-- 945 + TP ++ + T ++ +S EG L + P+S +VS Sbjct: 530 TLSTTP---VDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSE 586 Query: 946 -DFKSPIMADLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGETAKS---STLDIGALSL 1001 S AD N + + E +S + + G T S ST + + Sbjct: 587 ASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEA 646 Query: 1002 GLVVPCPERGKGPSGEADRLVLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKS-- 1059 + P P + + P ++ T S T ++ + S Sbjct: 647 STLSTTPVDSNTPVTTSTEATSSSTTAE-GTSMPTSTYTEGSTPLTSMPVNTTLVASSEA 705 Query: 1060 SSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDNPVPS--PSPSEIFPVTHSFPSSAHSD 1117 S+L S + SP+ G S+ PS +P PV+ + +S+ + Sbjct: 706 STLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEAS 765 Query: 1118 THH-----------TSTAESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPG 1166 T TST S T EG++ + + PLL + P PV++ P Sbjct: 766 TLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTS--IPVSITPVTS-PE 822 Query: 1167 AGT 1169 A T Sbjct: 823 AST 825 Score = 41.2 bits (95), Expect = 0.006 Identities = 72/325 (22%), Positives = 114/325 (35%), Gaps = 48/325 (14%) Query: 358 TENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANS 417 T + A S AEG L + SE ST S+ M L + A + L ++ Sbjct: 3431 TTSTEASSSPTIAEGTSLPTSTT-SEGSTPLSI--MPLSTTPVASSEASTLSTTPVDTST 3487 Query: 418 EATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLT------VPGREKEGMLMGVK 471 T + + P + + + T EG PLT P E + Sbjct: 3488 PVTTSSPTNSSPTTAEVTSMPTSTA-------GEGSTPLTNMPVSTTPVASSEASTLSTT 3540 Query: 472 P----------GEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKS 521 P + +S PA V T + S +++ L +T EA S Sbjct: 3541 PVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTM-LLSSTYVTSSEA-----S 3594 Query: 522 EPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELG 581 P P P T + + +P T + +P++ + L +P S+ ++ SE G Sbjct: 3595 TPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTI-SEAG 3653 Query: 582 HGA------------DTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPP 629 + TQ S SP + PI P STP+ + P+ SEG Sbjct: 3654 TASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGST 3713 Query: 630 LLPKAELQTESLTPVPNSGSSVLGS 654 L + + + TPV S ++ S Sbjct: 3714 LSTPSVVTS---TPVTTSTEAISSS 3735 Score = 37.7 bits (86), Expect = 0.071 Identities = 81/348 (23%), Positives = 123/348 (35%), Gaps = 57/348 (16%) Query: 362 AAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATK 421 A S PAEG ++ SE ST +L S+ + + A L A ++ T Sbjct: 1491 AVSSSPTPAEGTSIAISTP-SEGST--ALTSIPVSTTTVASSEINSLSTTPAVTSTPVTT 1547 Query: 422 EAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAE 481 ++ S P + + + T SEG PLT ML+ S Sbjct: 1548 YSQASSSPTTADGTSMQTSTY-------SEGSTPLT--SLPVSTMLVVSSEANTLSTTPI 1598 Query: 482 DLVRRSEKDTAAVVSR--QGSSLN---------LFEDVQI-TEPEAEPESKSEPRPPI-- 527 D + T A S +GSS+ L + + T P A PE+ + P+ Sbjct: 1599 DSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDS 1658 Query: 528 SSPRAPQTRAVKPRLEVSPEAQPTA-----RLPSPTDSPSSLPPLPSSSGQAS---VPSE 579 +SP T + PT+ R P + + + P S+ S V + Sbjct: 1659 NSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNS 1718 Query: 580 LGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTE 639 T++ SP+ S P + P +TP+ S P+ Sbjct: 1719 TPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPV---------------------- 1756 Query: 640 SLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSL 687 S TPV +S +S L + S P TE + T E GT TS+L Sbjct: 1757 STTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAE-GTSIPTSTL 1803 Score = 37.4 bits (85), Expect = 0.093 Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 22/136 (16%) Query: 1079 GNGSPSPPPGTSLDNPVPSP--SPSEIFPVTHSFPSSAH----------SDTHHTSTAES 1126 G+ SP+ GTS+ PS +P PV+ + S+ S T T++ E+ Sbjct: 2022 GSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEA 2081 Query: 1127 QKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNATA 1186 ATAEGS+ + + PLL + P T PV A P A T S P+++ + Sbjct: 2082 SSSATAEGSSMTISAPSEGSPLLTS--IPLSTTPV-ASPEASTLS-------TTPVDSNS 2131 Query: 1187 TKVANCSLGTATIISE 1202 + + + ++ I +E Sbjct: 2132 PVITSTEVSSSPIPTE 2147 Score = 36.6 bits (83), Expect = 0.16 Identities = 150/749 (20%), Positives = 239/749 (31%), Gaps = 123/749 (16%) Query: 472 PGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPR 531 P A G + SE +T ++R S + + + P S P S Sbjct: 2319 PPPTAEGTSMPTSTSSEGNTP--LTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAG 2376 Query: 532 APQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQAS----VPSELGHGADTQ 587 + T A + S ++ + L T P S P+ SS V + T+ Sbjct: 2377 SSPTTADDTSMPTSTYSEGSTPL---TSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTE 2433 Query: 588 SSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNS 647 +S SP+ S P + P +TP+ S P+ S TPV +S Sbjct: 2434 ASSSPTTAEGTSIPTSPPSEGTTPLASMPV----------------------STTPVVSS 2471 Query: 648 GSSVLGSLFKQPSFPANKGTEDSLMGRTRE-----TGTEKNTSSLELEESLPEQPETGRQ 702 + L + S P TE S T E T S+L + P + Sbjct: 2472 EAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPE 2531 Query: 703 EEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGD--RDLESQAGSLV 760 L P +S E + + S++G P + G R + L Sbjct: 2532 ASTLSTTPVDSNSPVVTSTEIS----SSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLA 2587 Query: 761 ESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEA 820 S+A P+ S+P S T VS S Sbjct: 2588 SSEA-----STLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVST 2642 Query: 821 VAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPAS 880 + A+ S+ P + + + S SP + +TPG ++ Sbjct: 2643 MPVASSEASTLSTTPVDTRTLVTTSTGTS-----SSPTTAEGSSMPTSTPGER-----ST 2692 Query: 881 PADHLLLPSQEESFSEVPMSEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSD 940 P ++L+ S + + SEAS+ TP+ + + ++AS Sbjct: 2693 PLTNILV-----STTLLANSEASTLSTTPV-----DTSTPVTTSAEASSSPTTAEGTSMR 2742 Query: 941 LQLVSDFKSPIMADLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALS 1000 + SD +P+ + L + ++P +S+ + D A SS S Sbjct: 2743 ISTPSDGSTPLTSIL---VSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTS 2799 Query: 1001 LGLVVPCPERGKGPSGEADRLVLGEGLCDFRLQAP-------QASVTAPSEQTTEFGIHK 1053 + P S + + P S A S TT GI Sbjct: 2800 MPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVV 2859 Query: 1054 P--HLGKSSSLDKQLP---GPSGGEEEKPM----------------GNGSPSPPPGTSLD 1092 P + S+L +P P E + G+ SP+ GTS+ Sbjct: 2860 PISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSM- 2918 Query: 1093 NPVPSPSPSEI-----------FPVTHSFPSSAHS---DTH---HTSTAESQKKATAEGS 1135 P +PSE+ PV S S+ + DT TS S TAEG+ Sbjct: 2919 ---PISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGT 2975 Query: 1136 AGRVENFGKRK-PLLQAWVSPSETHPVSA 1163 + + G+R+ PL VS T PV++ Sbjct: 2976 SMPISTPGERRTPLTSMSVS---TMPVAS 3001 Score = 35.4 bits (80), Expect = 0.35 Identities = 87/422 (20%), Positives = 142/422 (33%), Gaps = 40/422 (9%) Query: 511 TEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSS 570 TE + P + P S+P T + P + +P T S+L P Sbjct: 2196 TEARSSPTTSEGTSMPTSTPSEGSTPFT---------SMPVSTMPVVTSEASTLSATPVD 2246 Query: 571 SGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPL 630 + S T+++ SP+ S P + +TP+ S P+ A SE L Sbjct: 2247 TSTPVTTS-------TEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTL 2299 Query: 631 LPKA-------ELQTESLTPVPNS-GSSVLGSLFKQPSFPANKGTEDSLMGRTRETG--- 679 TE+ +P P + G+S+ S + + P + + M + ET Sbjct: 2300 STTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLS 2359 Query: 680 -TEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAV 738 T +TS+ S T + +P + +S +P S +S + Sbjct: 2360 TTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHST 2419 Query: 739 SPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMGLNL 798 +PV S + + E + + P+ AS+P + + E L+ Sbjct: 2420 TPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPL-ASMPVSTTPVVSSEAGTLST 2478 Query: 799 RKDQKKTKKRVS---FSEQLFTEEAVAGAALLVEGH---SSCPQELNPAWSVAGNASDGE 852 T S S E+ V + EG +S P P S + Sbjct: 2479 TPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTT 2538 Query: 853 PPE--SPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPM--SEASSAKDT 908 P + SP +E S T T P S P + S P+ SEAS+ T Sbjct: 2539 PVDSNSPVVTSTEISSSATSAEGT-SMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTT 2597 Query: 909 PL 910 P+ Sbjct: 2598 PV 2599 Score = 35.0 bits (79), Expect = 0.46 Identities = 67/329 (20%), Positives = 109/329 (33%), Gaps = 58/329 (17%) Query: 382 SESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPE----------- 430 SE ST L SM L + + L ++ AT + S P Sbjct: 1981 SEGSTP--LTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTST 2038 Query: 431 -SRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEK 489 S R++ L+ M + SEG T P K + + A+ + + Sbjct: 2039 PSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPS 2098 Query: 490 DTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQ 549 + + +++ S T P A PE+ + P+ S +P + + P Sbjct: 2099 EGSPLLTSIPLS---------TTPVASPEASTLSTTPVDS-NSPVITSTEVSSSPIPTEG 2148 Query: 550 PTARLPSPTDSPSSLPPLPSSS-----------GQASVPSELGHGADTQSSESPSVFSSL 598 + + + +D + L +P S+ V + T++ SP+ Sbjct: 2149 TSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGT 2208 Query: 599 SSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQ 658 S P + P STP S P+ S PV S +S L + Sbjct: 2209 SMPTSTPSEGSTPFTSMPV----------------------STMPVVTSEASTLSATPVD 2246 Query: 659 PSFPANKGTEDSLMGRTRETGTEKNTSSL 687 S P TE + T E GT TS+L Sbjct: 2247 TSTPVTTSTEATSSPTTAE-GTSIPTSTL 2274 Score = 34.3 bits (77), Expect = 0.79 Identities = 105/541 (19%), Positives = 191/541 (35%), Gaps = 54/541 (9%) Query: 155 ASMFDLSMKDKSRNPFGKLKDKIKGKNKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKK 214 ++ F S S +P ++ GS + + ++ S+T S+ + + Sbjct: 3544 SNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDR 3603 Query: 215 SKIKTLLSKSNLQKTPLSQSMSVLPTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMS 274 S T ++SN TP + LP S P +V P E+ +AS + Sbjct: 3604 STPVTTSTQSN--STPTPPEVITLPMSTPSEVST-PLTIMPVSTTSVTISEAGTASTLPV 3660 Query: 275 HKRTASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGE 334 ST + QV+ + EG + S+ G+ P + Sbjct: 3661 D---TSTPVITSTQVSSSPVTPEGTTMPIWTPSE------------GSTPLTTMPVSTTR 3705 Query: 335 IKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKE--------PAEGGGLSSDRQLSESST 386 + S S+ +P + +STE +++ + + P E L + +S + Sbjct: 3706 VTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPV 3765 Query: 387 KDSLKSMT--LPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKK 444 +S T +PS + ++ + +P E T S E R + L +++ Sbjct: 3766 TRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSE-RSTLLTTVLISPI 3824 Query: 445 DVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNL 504 V SE T PG +L K G S PAE R ++ S + + L Sbjct: 3825 SVMSPSEASTLSTPPGDTSTPLLTSTKAGS-FSIPAEVTTIR-----ISITSERSTPLTT 3878 Query: 505 FEDVQITEPEAEPESKSEPRPPI-------------SSPRAPQTRAVKPRLEVSPEAQP- 550 V T P + P + PP+ S+P P + + ++ + P Sbjct: 3879 LL-VSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSV-ITEGSTPG 3936 Query: 551 -TARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTS 609 T +PS + S+ P+++G S P +T S+ S S +S S+ +T Sbjct: 3937 TTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFST--TKEFTTP 3994 Query: 610 TPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTED 669 + PL + + P T + T S S+ +P P+++ + Sbjct: 3995 AMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRP 4054 Query: 670 S 670 S Sbjct: 4055 S 4055 Score = 30.8 bits (68), Expect = 8.7 Identities = 40/175 (22%), Positives = 61/175 (34%), Gaps = 28/175 (16%) Query: 511 TEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSS 570 TE + P + P S+P T + +P A S T +S P S Sbjct: 1725 TEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTS- 1783 Query: 571 SGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPL 630 T+++ SP+ S P + TP+ S P+ L Sbjct: 1784 ---------------TEATSSPTTAEGTSIPTSTLSEGMTPLTSTPV---------SHTL 1819 Query: 631 LPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTS 685 + +E T S TPV ++ V + PA +GT S+ T G+ TS Sbjct: 1820 VANSEASTLSTTPVDSNSPVVTSTAVSSSPTPA-EGT--SIATSTPSEGSTALTS 1871 >gi|209862789 microtubule associated monoxygenase, calponin and LIM domain containing 3 isoform 1 [Homo sapiens] Length = 2002 Score = 57.0 bits (136), Expect = 1e-07 Identities = 129/623 (20%), Positives = 222/623 (35%), Gaps = 108/623 (17%) Query: 202 SDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSV--LPTSKPEKVL-----LRPGDFQ 254 S ES ++++ ++ + + L S+L P +++ + L K E+ L PG+ + Sbjct: 934 SSSESEMEEEGEEEEEEPRLPPSDLGGVPWKEAVRIHALLKGKSEEELEASKSFGPGNEE 993 Query: 255 SQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSR 314 + +E++ E+E D + ++ ++L QV E Sbjct: 994 EEEEEEEYEEEEEEDYDE-EEEESSEAGNQRLQQVMHAADPLE----------------- 1035 Query: 315 SNVCINGNHVY-LEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLA--AGSWKEPAE 371 ++ H+ E+ E +SS S +P + ++ + S + A +P + Sbjct: 1036 IQADVHWTHIREREEEERMAPASESSASGAPLDENDLEEDVDSEPAEIEGEAAEDGDPGD 1095 Query: 372 GGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPES 431 G D Q S D+ + + LP PA EA E + S+ E Sbjct: 1096 TGAELDDDQHWSDSPSDADRELRLP----------------CPAEGEAELELRVSEDEEK 1139 Query: 432 RRSSLLSLMTGKKDVAKG-SEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKD 490 L K +G S+ +P+ P ++ +L GP V Sbjct: 1140 -------LPASPKHQERGPSQATSPIRSP--QESALLFIPVHSPSTEGPQLPPV------ 1184 Query: 491 TAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRP---PISSPRAPQTRAVKPRLEVSPE 547 A + LF + + + + + ++ S+ + PI S A P SP+ Sbjct: 1185 -PAATQEKSPEERLFPEPLLPKEKPKADAPSDLKAVHSPIRSQPVTLPEARTPVSPGSPQ 1243 Query: 548 AQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPIS 607 QP +P SP + P S +A+VPS ++SP F AP Sbjct: 1244 PQPPVAASTPPPSPLPICSQPQPSTEATVPS---------PTQSPIRFQ------PAPAK 1288 Query: 608 TSTPIESWPLVDRGQAKSE-GPPL-----LPKAELQTE------------SLTPVPNSGS 649 TSTP+ P+ + K G PL L +++L E LTPV S Sbjct: 1289 TSTPLAPLPVQSQSDTKDRLGSPLAVDEALRRSDLVEEFWMKSAEIRRSLGLTPVDRSKG 1348 Query: 650 SVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRF 709 +PSFP SL + E + L S+P++ + E E Sbjct: 1349 -------PEPSFPTPAFRPVSLKSYSVEKSPQDEGLHLLKPLSIPKRLGLPKPEGEPLSL 1401 Query: 710 PCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAE 769 P + AQE LS SS + ++ + L SQ+ + +S Sbjct: 1402 PTPRSPSDRELRSAQEERRELSSSSGLGLHG----SSSNMKTLGSQSFNTSDSAMLTPPS 1457 Query: 770 EVAPPLPMGASVPSIDSMMRKLE 792 PP P G ++ +R+ E Sbjct: 1458 SPPPPPPPGEEPATLRRKLREAE 1480 Score = 35.0 bits (79), Expect = 0.46 Identities = 85/424 (20%), Positives = 137/424 (32%), Gaps = 88/424 (20%) Query: 677 ETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDG 736 +TG E++ +S E + E+ G +EEE PR P P EA + L S+ Sbjct: 924 DTGAEEDVASSSSESEMEEE---GEEEEEEPRLPPSDLGGVPWK-EAVRIHALLKGKSEE 979 Query: 737 AVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMGL 796 + G + + E + E + D EE G + +M + + + Sbjct: 980 ELEASKSFGPGNEEE-EEEEEEYEEEEEEDYDEEEEESSEAGNQ--RLQQVMHAADPLEI 1036 Query: 797 NLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPES 856 ++R E+ A A L E + PA A DG+P ++ Sbjct: 1037 QADVHWTHIREREEEERMAPASESSASGAPLDENDLEEDVDSEPAEIEGEAAEDGDPGDT 1096 Query: 857 PHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLFRMEGE 916 D ++ +P + A L P++ E+ E+ +SE Sbjct: 1097 GAELDDDQHWSDSP------SDADRELRLPCPAEGEAELELRVSE--------------- 1135 Query: 917 DALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDERIDQVE 976 D E L + P + S SPI + +L IP + Sbjct: 1136 ------------DEEKLPASPKHQERGPSQATSPIRSPQESALLFIP--------VHSPS 1175 Query: 977 DDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFRLQAPQ 1036 +G Q+ VP + K P + + E L L + Sbjct: 1176 TEGPQLPP--------------------VPAATQEKSP----EERLFPEPL----LPKEK 1207 Query: 1037 ASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDNPVP 1096 APS+ +H P + +L E P+ GSP P P + P P Sbjct: 1208 PKADAPSDLKA---VHSPIRSQPVTLP---------EARTPVSPGSPQPQPPVAASTPPP 1255 Query: 1097 SPSP 1100 SP P Sbjct: 1256 SPLP 1259 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 56.6 bits (135), Expect = 1e-07 Identities = 108/571 (18%), Positives = 196/571 (34%), Gaps = 52/571 (9%) Query: 158 FDLSMKDKSRNPFGKLKDKIKGKNKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKI 217 F +KD +N K ++GS + TTP + + V K + Sbjct: 62 FCAEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA 121 Query: 218 KTLLSKSNLQKTPLSQSMSVLPTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKR 277 K + + +L + + L +K V + ++ D +++++SA + S ++ Sbjct: 122 KPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 181 Query: 278 TASTDLKQLNQV-NFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIK 336 T++ DL ++V PK E +K L+ K Sbjct: 182 TSAKDLAPTSKVLAKPTPKAE-------TTTKGPALTTP--------------------K 214 Query: 337 DSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLP 396 + +P++ P K +T A + KEPA S+ E + + + Sbjct: 215 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 274 Query: 397 SYRPAPLVSGDLRENMAPANSEATKEAKES--KKPESRRSSLLSLMTGKKDVAKGSEGEN 454 PAP + + + KE + KKP + T K+ + Sbjct: 275 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 334 Query: 455 PLT---VPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQIT 511 P T P KE P + A ++ + K+ A +++ S E T Sbjct: 335 PTTKEPAPTTPKEP--APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 392 Query: 512 EPEAEPESKSEPRPPI-----SSPRAPQTRAVKPRLEVSPE--AQPTARLPSPTDSPSSL 564 A P + EP P ++P+ P K +P+ A T + P+PT Sbjct: 393 TKSA-PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 451 Query: 565 P-----PLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVD 619 P P P+++ + + + T +P+ L+ ++ +TP + P Sbjct: 452 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 511 Query: 620 RGQAKS---EGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTR 676 A + E P P+ T PN+ + K+P+ K + T Sbjct: 512 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 571 Query: 677 ETGTEKNTSSLELEESLPEQPETGRQEEELP 707 T T K T+ L+E P P+ +E P Sbjct: 572 PT-TPKGTAPTTLKEPAPTTPKKPAPKELAP 601 Score = 52.0 bits (123), Expect = 4e-06 Identities = 85/397 (21%), Positives = 132/397 (33%), Gaps = 52/397 (13%) Query: 326 LEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESS 385 +E+ AK S + P+PK ++T+ A + KEP + Sbjct: 179 IEKTSAKDLAPTSKVLAKPTPKAE------TTTKGPALTTPKEPTPTTPKEPASTTPKEP 232 Query: 386 TKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKD 445 T ++KS PAP + TKE + E T K+ Sbjct: 233 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP-------TTTKE 285 Query: 446 VAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLF 505 A + P T P E A + + K+ A ++ + Sbjct: 286 PAPTTTKSAPTT--------------PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK 331 Query: 506 EDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPE--AQPTARLPSPTDSPSS 563 E T+ E P + EP P ++P+ P K +P+ A T + PSPT Sbjct: 332 EPAPTTK-EPAPTTPKEPAP--TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT----- 383 Query: 564 LPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQA 623 P P+ + S P+ A T + +P+ S + +TP E P + A Sbjct: 384 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 443 Query: 624 KSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEK- 682 P PK T P P + + K+P+ K T + + T EK Sbjct: 444 -----PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 498 Query: 683 ---------NTSSLELEESLPEQPETGRQEEELPRFP 710 T+ EL + PE+P EE P P Sbjct: 499 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 535 Score = 46.6 bits (109), Expect = 2e-04 Identities = 78/385 (20%), Positives = 131/385 (34%), Gaps = 39/385 (10%) Query: 336 KDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTL 395 K+ +P+++ P K +T A + KEPA S+ E S + + Sbjct: 370 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 429 Query: 396 PSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENP 455 PAP PA + + A + K + ++ T K+ A + E Sbjct: 430 TPKEPAPTTP------KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 483 Query: 456 LTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEA 515 T P + L P + A E + ++ A + + E T A Sbjct: 484 PTTPKK-----LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 538 Query: 516 EPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQAS 575 P + EP P ++P+ P A T + P+PT + P P + + Sbjct: 539 APNTPKEPAP--TTPKEP--------------APTTPKEPAPTTPKETAPTTP----KGT 578 Query: 576 VPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAE 635 P+ L A T + + P+ + P ST T + P +G A P PK Sbjct: 579 APTTLKEPAPT-TPKKPAPKELAPTTTKEPTST-TCDKPAPTTPKGTA-----PTTPKEP 631 Query: 636 LQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPE 695 T P P + + K+P+ K + T G TS + + P+ Sbjct: 632 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPK 690 Query: 696 QPETGRQEEELPRFPCKKQDYSPSS 720 + +E P P K +P + Sbjct: 691 ETAPTTPKEPAPTTPKKPAPTTPET 715 Score = 44.7 bits (104), Expect = 6e-04 Identities = 72/357 (20%), Positives = 118/357 (33%), Gaps = 27/357 (7%) Query: 376 SSDRQLSESSTKDSLKSMTLPSYRPA-PLVSGDLRENMAPANSEATKEAKES-------- 426 +S Q ++ ST + + + RP+ P S +E N E T E KE+ Sbjct: 104 TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 163 Query: 427 ----KKPESRRSSLLSLMTGKKDVAKGSEG-ENPLTVPGREKEGMLMGVKPGEDASGPAE 481 +K S + + T KD+A S+ P +G + + P E Sbjct: 164 TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE 223 Query: 482 DLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPR 541 ++ T + S+ ++ T ++ P + EP P + AP T +P Sbjct: 224 PASTTPKEPTPTTIK---SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK-EPA 279 Query: 542 LEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSP 601 + E PT +PT P P P+ A T E +P Sbjct: 280 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA----PTTPKEPAPTTPKEPTPTTPKEPAP 335 Query: 602 IAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSF 661 + +TP E P + A P PK T P P + + K+P+ Sbjct: 336 TTKEPAPTTPKEPAPTAPKKPA-----PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 390 Query: 662 PANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSP 718 K + T T+ E + ++P +E P P K +P Sbjct: 391 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 447 Score = 32.3 bits (72), Expect = 3.0 Identities = 49/253 (19%), Positives = 87/253 (34%), Gaps = 23/253 (9%) Query: 489 KDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP--RLEVSP 546 K+ A ++ +S + T E P + EP P AP T P EVS Sbjct: 666 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 725 Query: 547 EA---QPTARLPSPTDSPSSLPPLPSSSGQASVPSELG-HGADTQSSESPSVFSSLSSPI 602 +PT SP +S L P+ + P E G T ++ P + ++ Sbjct: 726 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 785 Query: 603 AAPISTSTP--IESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGS-----SVLGSL 655 +TP + P + + A + K T +T + + L + Sbjct: 786 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 845 Query: 656 FKQPSFPANKGT----------EDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEE 705 P K T E++ + R T ++ T + P++P + ++ + Sbjct: 846 TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT 905 Query: 706 LPRFPCKKQDYSP 718 +PR K +P Sbjct: 906 MPRVRKPKTTPTP 918 Score = 32.0 bits (71), Expect = 3.9 Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 15/93 (16%) Query: 1059 SSSLDKQLP------GPSGGEEEKPMGNGSPSP--PPGTS---LDNPVPS----PSPSEI 1103 S++ DK P P+ +E P P+P P GT+ L P P+ P+P E+ Sbjct: 609 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 668 Query: 1104 FPVTHSFPSSAHSDTHHTSTAESQKKATAEGSA 1136 P T P+S SD +T + T + A Sbjct: 669 APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 701 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 56.6 bits (135), Expect = 1e-07 Identities = 108/571 (18%), Positives = 196/571 (34%), Gaps = 52/571 (9%) Query: 158 FDLSMKDKSRNPFGKLKDKIKGKNKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKI 217 F +KD +N K ++GS + TTP + + V K + Sbjct: 103 FCAEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA 162 Query: 218 KTLLSKSNLQKTPLSQSMSVLPTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKR 277 K + + +L + + L +K V + ++ D +++++SA + S ++ Sbjct: 163 KPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 222 Query: 278 TASTDLKQLNQV-NFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIK 336 T++ DL ++V PK E +K L+ K Sbjct: 223 TSAKDLAPTSKVLAKPTPKAE-------TTTKGPALTTP--------------------K 255 Query: 337 DSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLP 396 + +P++ P K +T A + KEPA S+ E + + + Sbjct: 256 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 315 Query: 397 SYRPAPLVSGDLRENMAPANSEATKEAKES--KKPESRRSSLLSLMTGKKDVAKGSEGEN 454 PAP + + + KE + KKP + T K+ + Sbjct: 316 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 375 Query: 455 PLT---VPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQIT 511 P T P KE P + A ++ + K+ A +++ S E T Sbjct: 376 PTTKEPAPTTPKEP--APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 433 Query: 512 EPEAEPESKSEPRPPI-----SSPRAPQTRAVKPRLEVSPE--AQPTARLPSPTDSPSSL 564 A P + EP P ++P+ P K +P+ A T + P+PT Sbjct: 434 TKSA-PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 492 Query: 565 P-----PLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVD 619 P P P+++ + + + T +P+ L+ ++ +TP + P Sbjct: 493 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 552 Query: 620 RGQAKS---EGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTR 676 A + E P P+ T PN+ + K+P+ K + T Sbjct: 553 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 612 Query: 677 ETGTEKNTSSLELEESLPEQPETGRQEEELP 707 T T K T+ L+E P P+ +E P Sbjct: 613 PT-TPKGTAPTTLKEPAPTTPKKPAPKELAP 642 Score = 52.0 bits (123), Expect = 4e-06 Identities = 85/397 (21%), Positives = 132/397 (33%), Gaps = 52/397 (13%) Query: 326 LEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESS 385 +E+ AK S + P+PK ++T+ A + KEP + Sbjct: 220 IEKTSAKDLAPTSKVLAKPTPKAE------TTTKGPALTTPKEPTPTTPKEPASTTPKEP 273 Query: 386 TKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKD 445 T ++KS PAP + TKE + E T K+ Sbjct: 274 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP-------TTTKE 326 Query: 446 VAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLF 505 A + P T P E A + + K+ A ++ + Sbjct: 327 PAPTTTKSAPTT--------------PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK 372 Query: 506 EDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPE--AQPTARLPSPTDSPSS 563 E T+ E P + EP P ++P+ P K +P+ A T + PSPT Sbjct: 373 EPAPTTK-EPAPTTPKEPAP--TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT----- 424 Query: 564 LPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQA 623 P P+ + S P+ A T + +P+ S + +TP E P + A Sbjct: 425 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 484 Query: 624 KSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEK- 682 P PK T P P + + K+P+ K T + + T EK Sbjct: 485 -----PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 539 Query: 683 ---------NTSSLELEESLPEQPETGRQEEELPRFP 710 T+ EL + PE+P EE P P Sbjct: 540 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 576 Score = 46.6 bits (109), Expect = 2e-04 Identities = 78/385 (20%), Positives = 131/385 (34%), Gaps = 39/385 (10%) Query: 336 KDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTL 395 K+ +P+++ P K +T A + KEPA S+ E S + + Sbjct: 411 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 470 Query: 396 PSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENP 455 PAP PA + + A + K + ++ T K+ A + E Sbjct: 471 TPKEPAPTTP------KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 524 Query: 456 LTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEA 515 T P + L P + A E + ++ A + + E T A Sbjct: 525 PTTPKK-----LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 579 Query: 516 EPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQAS 575 P + EP P ++P+ P A T + P+PT + P P + + Sbjct: 580 APNTPKEPAP--TTPKEP--------------APTTPKEPAPTTPKETAPTTP----KGT 619 Query: 576 VPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAE 635 P+ L A T + + P+ + P ST T + P +G A P PK Sbjct: 620 APTTLKEPAPT-TPKKPAPKELAPTTTKEPTST-TCDKPAPTTPKGTA-----PTTPKEP 672 Query: 636 LQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPE 695 T P P + + K+P+ K + T G TS + + P+ Sbjct: 673 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPK 731 Query: 696 QPETGRQEEELPRFPCKKQDYSPSS 720 + +E P P K +P + Sbjct: 732 ETAPTTPKEPAPTTPKKPAPTTPET 756 Score = 44.7 bits (104), Expect = 6e-04 Identities = 72/357 (20%), Positives = 118/357 (33%), Gaps = 27/357 (7%) Query: 376 SSDRQLSESSTKDSLKSMTLPSYRPA-PLVSGDLRENMAPANSEATKEAKES-------- 426 +S Q ++ ST + + + RP+ P S +E N E T E KE+ Sbjct: 145 TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 204 Query: 427 ----KKPESRRSSLLSLMTGKKDVAKGSEG-ENPLTVPGREKEGMLMGVKPGEDASGPAE 481 +K S + + T KD+A S+ P +G + + P E Sbjct: 205 TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE 264 Query: 482 DLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPR 541 ++ T + S+ ++ T ++ P + EP P + AP T +P Sbjct: 265 PASTTPKEPTPTTIK---SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK-EPA 320 Query: 542 LEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSP 601 + E PT +PT P P P+ A T E +P Sbjct: 321 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA----PTTPKEPAPTTPKEPTPTTPKEPAP 376 Query: 602 IAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSF 661 + +TP E P + A P PK T P P + + K+P+ Sbjct: 377 TTKEPAPTTPKEPAPTAPKKPA-----PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 431 Query: 662 PANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSP 718 K + T T+ E + ++P +E P P K +P Sbjct: 432 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 488 Score = 32.3 bits (72), Expect = 3.0 Identities = 49/253 (19%), Positives = 87/253 (34%), Gaps = 23/253 (9%) Query: 489 KDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKP--RLEVSP 546 K+ A ++ +S + T E P + EP P AP T P EVS Sbjct: 707 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 766 Query: 547 EA---QPTARLPSPTDSPSSLPPLPSSSGQASVPSELG-HGADTQSSESPSVFSSLSSPI 602 +PT SP +S L P+ + P E G T ++ P + ++ Sbjct: 767 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 826 Query: 603 AAPISTSTP--IESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGS-----SVLGSL 655 +TP + P + + A + K T +T + + L + Sbjct: 827 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 886 Query: 656 FKQPSFPANKGT----------EDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEE 705 P K T E++ + R T ++ T + P++P + ++ + Sbjct: 887 TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT 946 Query: 706 LPRFPCKKQDYSP 718 +PR K +P Sbjct: 947 MPRVRKPKTTPTP 959 Score = 32.0 bits (71), Expect = 3.9 Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 15/93 (16%) Query: 1059 SSSLDKQLP------GPSGGEEEKPMGNGSPSP--PPGTS---LDNPVPS----PSPSEI 1103 S++ DK P P+ +E P P+P P GT+ L P P+ P+P E+ Sbjct: 650 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 709 Query: 1104 FPVTHSFPSSAHSDTHHTSTAESQKKATAEGSA 1136 P T P+S SD +T + T + A Sbjct: 710 APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 742 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 56.6 bits (135), Expect = 1e-07 Identities = 84/302 (27%), Positives = 117/302 (38%), Gaps = 45/302 (14%) Query: 327 EQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESST 386 E P+ +++SS S SP+PK +KK + S + + + S Sbjct: 166 EPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESK 225 Query: 387 KDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDV 446 K +S T S R + + PA ++ A S +S SS S + Sbjct: 226 KRKHRSPTPKSKRKSKDKKRKRSRSTTPA--PKSRRAHRSTSADSASSSDTSRSRSRSAA 283 Query: 447 AK----GSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSL 502 AK G +P GR EG +PG ++ R S +TA ++Q SS Sbjct: 284 AKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTST------QRPSSPETA---TKQPSS- 333 Query: 503 NLFED-------VQITEPEAEPE-SKSEPRPPISSP-------RAPQTRAVKPRLE--VS 545 +ED T P PE S + P PP +P +PQ A P + V+ Sbjct: 334 -PYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN 392 Query: 546 P--EAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIA 603 P EA PT R SP SP LP SSS ++S PS +S SP SP Sbjct: 393 PPSEASPT-RDRSPPKSPEKLP--QSSSSESSPPSPQPTKVSRHASSSP------ESPKP 443 Query: 604 AP 605 AP Sbjct: 444 AP 445 Score = 51.2 bits (121), Expect = 6e-06 Identities = 89/398 (22%), Positives = 139/398 (34%), Gaps = 48/398 (12%) Query: 533 PQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESP 592 P T A P +P+A +A L P + ++ P + S A+ L + T + +P Sbjct: 2317 PPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAA---LAPASLTSARMAP 2373 Query: 593 SVF-SSLSSPIAAPISTSTPIE---SWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNS- 647 ++ ++L+SP P+S + S PL+DR A+S PP P T P P+S Sbjct: 2374 ALSGANLTSP-RVPLSAYERVSGRTSPPLLDR--ARSRTPPSAPSQSRMTSERAPSPSSR 2430 Query: 648 -----GSSVLGSLFKQPSFPANKGTEDS----LMGRTRETGTEKNTSSLELEESLPEQPE 698 S+L QP P D + T G++ +S + Sbjct: 2431 MGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDH 2490 Query: 699 TGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSL--------SSDGAVSPVGELAAGGDR 750 G P P P+S AQ+ P AL+ SS + S ++ Sbjct: 2491 NGMLSVPAPGVPHSDVGEPPASTGAQQ-PSALAALQPAKERRSSSSSSSSSSSSSSSSSS 2549 Query: 751 DLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVS 810 S + S + ++ V P + + VPS ++ G K K+R S Sbjct: 2550 SSSSSSSGSSSSDSEGSSLPVQPEVAL-KRVPSPTPAPKEAVREGRPPEPTPAKRKRRSS 2608 Query: 811 FSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSERESVTTP 870 S SS + + S + ++S S + S S P Sbjct: 2609 SSSS--------------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP 2654 Query: 871 GPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDT 908 GP PASP P E S P S +D+ Sbjct: 2655 GPQALPKPASPKK----PPPGERRSRSPRKPIDSLRDS 2688 Score = 42.4 bits (98), Expect = 0.003 Identities = 73/328 (22%), Positives = 122/328 (37%), Gaps = 34/328 (10%) Query: 513 PEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSS-S 571 P + + PR P+S+ R P L+ + P + PS + S P PSS Sbjct: 2373 PALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPS-APSQSRMTSERAPSPSSRM 2431 Query: 572 GQASVPSELGHGADTQSSESPSVFSSLSSPIAA---PISTSTPIESWPLV-------DRG 621 GQA S L D S PS FS S + A P++ S + S + D Sbjct: 2432 GQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHN 2491 Query: 622 QAKSEGPPLLPKAELQTESLTPVPNSGS---SVLGSL-----FKQPSFPANKGTEDSLMG 673 S P +P +++ P ++G+ S L +L + S ++ + S Sbjct: 2492 GMLSVPAPGVPHSDVG----EPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSS 2547 Query: 674 RTRETGTEKNTSSLELE-ESLPEQPETGRQEEELPRFPCKKQDY------SPSSGEAQEV 726 + + + +SS + E SLP QPE + P P K+ P+ + + Sbjct: 2548 SSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT-PAPKEAVREGRPPEPTPAKRKRR 2606 Query: 727 PFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDS 786 + S SS + S ++ S + S S + ++ A P P P+ Sbjct: 2607 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPK 2666 Query: 787 MMRKLEEMGLNLRK--DQKKTKKRVSFS 812 E + RK D + + +S+S Sbjct: 2667 KPPPGERRSRSPRKPIDSLRDSRSLSYS 2694 Score = 41.2 bits (95), Expect = 0.006 Identities = 74/311 (23%), Positives = 101/311 (32%), Gaps = 44/311 (14%) Query: 329 PEAKGEIKDS----SPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSES 384 P++K + KD S S++P+PK R+ H +S ++ + SSD S S Sbjct: 234 PKSKRKSKDKKRKRSRSTTPAPKS-RRAHRSTSADSAS-------------SSDTSRSRS 279 Query: 385 STKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKK 444 + + T + R SG E AP + T + PE+ S K Sbjct: 280 RSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKD 339 Query: 445 DVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNL 504 K P P R G P A P A +N Sbjct: 340 KDKKEKSATRPSPSPERSSTG------PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNP 393 Query: 505 FEDVQITE---PEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSP 561 + T P PE + SSP +PQ V SPE+ P P +P Sbjct: 394 PSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPES------PKPAPAP 447 Query: 562 SSLPPLPSSSGQASVPSELGHG---ADTQSSESPSVFSSLS-SPIAAPISTSTPIESWPL 617 S + SS HG D S +PS S SP A S S Sbjct: 448 GSHREISSS----PTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRS---RSRTP 500 Query: 618 VDRGQAKSEGP 628 RG ++S P Sbjct: 501 TKRGHSRSRSP 511 Score = 41.2 bits (95), Expect = 0.006 Identities = 75/324 (23%), Positives = 116/324 (35%), Gaps = 33/324 (10%) Query: 376 SSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSS 435 S R SE + S + PS P R + A S+ ++ P + S Sbjct: 2415 SQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQS 2474 Query: 436 LLS----------------LMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGP 479 L S L V GE P + G ++ L ++P ++ Sbjct: 2475 LSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPAST-GAQQPSALAALQPAKER--- 2530 Query: 480 AEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEP-RPPISSPRAPQ-TRA 537 R S +++ S SS + ++ E S P +P ++ R P T A Sbjct: 2531 -----RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA 2585 Query: 538 VKPRLEVS--PEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVF 595 K + PE P R + S SS SSS +S S + + SS S S Sbjct: 2586 PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645 Query: 596 SSLSSPIAAPISTSTPIESWP-LVDRGQAKSEGP--PLLPKAELQTESLTPVPNSGSSVL 652 SS SP A P + P + P G+ +S P P+ + ++ S +PV S Sbjct: 2646 SSSPSP-AKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQ 2704 Query: 653 GSLFKQPSFPANKGTEDSLMGRTR 676 S Q S + +G+ G +R Sbjct: 2705 PSPRDQQSSSSERGSRRGQRGDSR 2728 Score = 39.7 bits (91), Expect = 0.019 Identities = 103/476 (21%), Positives = 166/476 (34%), Gaps = 67/476 (14%) Query: 179 GKNKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVL 238 G+ SGS + PS +P S+ +S D K K++ L +S +P S S L Sbjct: 1534 GQRSRSGSSQELDVKPSASPQERSESDS-SPDSKAKTR-TPLRQRSRSGSSPEVDSKSRL 1591 Query: 239 PT------SKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFT 292 S PE ++Q D + + + A + + + + K Sbjct: 1592 SPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRG----- 1646 Query: 293 LPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKK 352 P EG S S + +S G+ E P+ K SS SP+ RK Sbjct: 1647 -PSPEGSS---STESSPEHPPKSRTARRGSRSSPE-PKTKSRTPPRRRSSRSSPELTRKA 1701 Query: 353 HLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENM 412 L S R S SS+ ++ +S T P +R +P VS Sbjct: 1702 RL----------------------SRRSRSASSSPET-RSRTPPRHRRSPSVS------- 1731 Query: 413 APANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKP 472 +P +E ++ ++ + S R+ S G+ K + + REK Sbjct: 1732 SPEPAEKSRSSRRRRSASSPRTKTTS-RRGRSPSPKPRGLQRSRSRSRREK----TRTTR 1786 Query: 473 GEDASGPAEDLVRRSEKD---TAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISS 529 D SG ++ RR ++ + R+G S P + S++ R Sbjct: 1787 RRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGS-----GYHSRSPARQESSRTSSRRRRGR 1841 Query: 530 PRAPQTRAVKPRLEVSPEAQPTAR---LPSPTDSPSSLPPLPSSSGQASVPSELGHGADT 586 R P T + R SP +R P+ S PL S S S + Sbjct: 1842 SRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSR---R 1898 Query: 587 QSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLT 642 +S SV S A+P+S P V R +++S P ++ +T +T Sbjct: 1899 RSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVT 1954 Score = 39.3 bits (90), Expect = 0.024 Identities = 147/655 (22%), Positives = 224/655 (34%), Gaps = 146/655 (22%) Query: 313 SRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFR----------KKHLFSSTENLA 362 SRS + + P+ +G SS + S R KK SS + + Sbjct: 702 SRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRS 761 Query: 363 AGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKE 422 S + A+ LS R LS SS KS T P + + P S ++ Sbjct: 762 LSSPRSKAKSR-LSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSS 820 Query: 423 A--KESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPA 480 K+ K SR+S S K V G+ + E + + S P Sbjct: 821 PPPKQKSKTPSRQSHSSSSPHPK--VKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPD 878 Query: 481 EDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRA--- 537 +L R T + S GSS + T P P S P+P + + +P+ R+ Sbjct: 879 PELKSR----TPSRHSCSGSSPPRVKSS--TPPRQSPSRSSSPQPKVKAIISPRQRSHSG 932 Query: 538 ------------VKPR--LEVSPEAQPTAR-LPSPTDSPSS---------LPPLPSSSGQ 573 PR VSP + +R LP + S SS PP S SG Sbjct: 933 SSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGS 992 Query: 574 AS----VPSELGHGADTQSSESP--------SVFSSL--SSPIAAPISTSTP-------I 612 S V ++ G S+SP S+ S S + A + +STP + Sbjct: 993 ISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGV 1052 Query: 613 ESWPLVDRG----------------QAKSEGPPLLPKAELQTE----------------- 639 S L + Q+ SE P L K++ + Sbjct: 1053 SSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRS 1112 Query: 640 ---------SLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTR-ETGTEKNTSSLEL 689 S +P+ SG S S F+ S +SL+G++R ET K +L Sbjct: 1113 PIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPP 1172 Query: 690 EESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGD 749 +E P RQ+++ FP Q+ P + + D +P E Sbjct: 1173 QEDATASPP--RQKDKFSPFP------------VQDRPESSLVFKDTLRTPPRE------ 1212 Query: 750 RDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMG---LNLRKDQKKTK 806 S AGS E+K +++A LP + + ++ K EE L+ + K Sbjct: 1213 ---RSGAGSSPETKEQNSA------LPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEM 1263 Query: 807 KRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPESPHAED 861 +F EE A + L + S E S+A +S G P SP ++ Sbjct: 1264 STSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMA--SSWGGPHFSPEHKE 1316 Score = 39.3 bits (90), Expect = 0.024 Identities = 56/248 (22%), Positives = 83/248 (33%), Gaps = 41/248 (16%) Query: 327 EQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESST 386 +QP A ++ + S S SS+ + ++ S + G SSD + S Sbjct: 2516 QQPSALAALQPAKERRSSSSSSSS-----SSSSSSSSSSSSSSSSSGSSSSDSEGSSLPV 2570 Query: 387 KDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDV 446 + + +PS PAP + +RE P + A ++ + S S SS S + Sbjct: 2571 QPEVALKRVPSPTPAPKEA--VREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSS 2628 Query: 447 AKGSEGENPLTVPGREKEGMLMGVKPGEDA-SGPAEDLVRRSEKDTAAVVSRQGSSLNLF 505 + S + + KPG A PA Sbjct: 2629 SSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPK---------------------- 2666 Query: 506 EDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLP 565 P E S+S PR PI S R ++ + P P Q PSP D SS Sbjct: 2667 -----KPPPGERRSRS-PRKPIDSLRDSRSLSYSPVERRRPSPQ-----PSPRDQQSSSS 2715 Query: 566 PLPSSSGQ 573 S GQ Sbjct: 2716 ERGSRRGQ 2723 Score = 38.1 bits (87), Expect = 0.054 Identities = 139/651 (21%), Positives = 225/651 (34%), Gaps = 100/651 (15%) Query: 170 FGKLKDKIKGKNK---DSGSDTASAIIP---STTPSVDSDDESVVKDKKKKSK--IKTLL 221 FG ++KG+++ D SDT+S + S +PS+ S ++ K + +S + L Sbjct: 1050 FGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELA 1109 Query: 222 SKSNLQKTPLSQSMSVLPTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTAST 281 S+S P+ Q S K + P QS++ D + + ++ ++ R + Sbjct: 1110 SRS-----PIRQDRGEFSASPMLKSGMSPE--QSRFQSDSSSYPTVDSNSLLGQSRLETA 1162 Query: 282 DLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKD---- 337 + K+ LP +E + + D S V ++PE+ KD Sbjct: 1163 ESKE----KMALPPQEDAT--ASPPRQKDKFSPFPV--------QDRPESSLVFKDTLRT 1208 Query: 338 -----SSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKS 392 S SSP K SS + ++ E G SE + Sbjct: 1209 PPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNF 1268 Query: 393 MTLPSYRPAPLVSGDLRENMAPANSEATK---------------EAKESKKPESRRSSLL 437 + P P VS L ++ + A+ EA + E KE R +S Sbjct: 1269 ESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFG 1328 Query: 438 SLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDT------ 491 S + + G+E + +E L G + + P+ D+ +S + + Sbjct: 1329 SPLEFRNSGPLGTEMNTGFSSEVKED---LNGPFLNQLETDPSLDMKEQSTRSSGHSSSE 1385 Query: 492 --------AAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLE 543 A + S Q S + + V T S S P PR P R+ Sbjct: 1386 LSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRS------ 1439 Query: 544 VSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHG-ADTQSSESPSVFSSLSSPI 602 + P R S T S SL SS G +P G ++ SS P P Sbjct: 1440 -RSGSSPGLRDGSGTPSRHSLS--GSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPR 1496 Query: 603 AAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPV---PNSGSSVLGSLFKQP 659 + S+ R ++ SE + +T + TP+ SGSS + K Sbjct: 1497 SRSPSSPELNNKCLTPQRERSGSES-----SVDQKTVARTPLGQRSRSGSSQELDV-KPS 1550 Query: 660 SFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPS 719 + P + DS +T T L PE + PR + S S Sbjct: 1551 ASPQERSESDSSPDSKAKTRT-----PLRQRSRSGSSPEVDSKSRLSPR-----RSRSGS 1600 Query: 720 SGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEE 770 S E ++ P A + G+ S E A R L ++ S SK R + E Sbjct: 1601 SPEVKDKPRAAPRAQSGSDSS-PEPKAPAPRALPRRSRSGSSSKGRGPSPE 1650 Score = 36.2 bits (82), Expect = 0.21 Identities = 111/499 (22%), Positives = 171/499 (34%), Gaps = 94/499 (18%) Query: 687 LELEESLPEQPETGRQ-EEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELA 745 LELEE + EQ +Q +E++ F + + G +E P AV+ +LA Sbjct: 71 LELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETP-----GQRPAVTETHQLA 125 Query: 746 AGGDRDLESQ------AGSLVESKARDA---AEEVAPPLPMGASVPSIDSMMRKLEEMGL 796 ++ E + S V+ + D A E P P P S++R+ Sbjct: 126 ELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAP---EPPKPYSLVRESSSSRS 182 Query: 797 NLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPES 856 K +KK KK+ ++ E S ++ + + S + P + Sbjct: 183 PTPKQKKKKKKKDRGRRS-------ESSSPRRERKKSSKKKKHRSESESKKRKHRSP--T 233 Query: 857 PHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLFRMEGE 916 P ++ ++ +T AP S H + S S+ S + SA Sbjct: 234 PKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAA-----AKTHT 288 Query: 917 DALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDERIDQVE 976 AL + S AS G P S+ S + PS PE A+ + Sbjct: 289 TALAGRSPSPASGRRGEGDAPFSEPGTTSTQR-----------PSSPETATKQPSSPYED 337 Query: 977 DDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGK-GPSGEADRLVLGEGLCDFRLQAP 1035 D D+ E KS+T P PER GP A +L E +P Sbjct: 338 KDKDKKE------KSATRPS---------PSPERSSTGPEPPAPTPLLAER----HGGSP 378 Query: 1036 QASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDNPV 1095 Q T P Q P S + D+ P E+ P + S S PP Sbjct: 379 QPLATTPLSQEPV----NPPSEASPTRDRS---PPKSPEKLPQSSSSESSPP-------- 423 Query: 1096 PSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVEN--FGKRKPLLQAWV 1153 SP P+++ H +S+ ES K A A GS + + K + +A Sbjct: 424 -SPQPTKV-------------SRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKR 469 Query: 1154 SPSETHPVSAQPGAGTGSA 1172 S +H S + G A Sbjct: 470 DKSHSHTPSRRMGRSRSPA 488 Score = 32.7 bits (73), Expect = 2.3 Identities = 62/282 (21%), Positives = 95/282 (33%), Gaps = 28/282 (9%) Query: 337 DSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLP 396 DSSP P+ R + S+ L E G SESS + T Sbjct: 1481 DSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSG-------SESSVDQKTVARTPL 1533 Query: 397 SYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPL 456 R SG +E ++ + ++ P+S+ + L + + Sbjct: 1534 GQRSR---SGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR 1590 Query: 457 TVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVV------SRQGSSLNLFEDVQI 510 P R + G VK A+ A+ S + A SR GSS + Sbjct: 1591 LSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSS----SKGRG 1646 Query: 511 TEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSS 570 PE ++S P P P++R + SPE + +R P S S P L Sbjct: 1647 PSPEGSSSTESSPEHP------PKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRK 1700 Query: 571 SGQASVPSELGHGADTQSSESP--SVFSSLSSPIAAPISTST 610 + + +T+S P S+SSP A S S+ Sbjct: 1701 ARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSS 1742 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 54.3 bits (129), Expect = 7e-07 Identities = 125/598 (20%), Positives = 215/598 (35%), Gaps = 104/598 (17%) Query: 328 QPEAKGEIKDSSP----SSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSE 383 QP+ KD++P S +P PK + + K+P E LS E Sbjct: 678 QPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKE 737 Query: 384 SSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGK 443 S + +P ++ ++S TK S K +S+ + K Sbjct: 738 PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL-K 796 Query: 444 KDVAKGSEGENPL--TVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSS 501 D AK S+ P V + + + + S P + +K V ++ Sbjct: 797 TDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK 856 Query: 502 LNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTAR-----LPS 556 + +P+A+P K P PP P A QT P + SP+ Q +R L S Sbjct: 857 KA--QTKMSPKPDAKPMPKGSPTPPGPRPTAGQT---VPTPQQSPKPQEQSRRFSLNLGS 911 Query: 557 PTDSPSSLPPLP-----------------------SSSGQASVPSELGHGADTQSSESPS 593 TD+P S P P S++GQ S+ G GA + + +PS Sbjct: 912 ITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPS 971 Query: 594 VFSSLSSPIAAPIST---------STPIE---SWPLVDRGQAKSEGPPLLPKAELQ---- 637 + P P ST S P++ P ++ + K+E P + + E + Sbjct: 972 QPPTSQGP---PKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPP 1028 Query: 638 ----TESLTPVPNSGSSVLGSLFKQPSFP----------ANKGTEDSLMGRT-------- 675 ++SLT P +VL + ++ P N G++D T Sbjct: 1029 PIKDSKSLTAEPQ--KAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQV 1086 Query: 676 -RETGTEKNTSSLELEESLPEQPETGR----QEEELPRFPCKKQDYSPSSGEAQEVPFAL 730 G E++E L +T R Q ++ + P +PS +A +P Sbjct: 1087 CNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP-----PAPSGPKASPMPVPT 1141 Query: 731 SLSSD-GAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMR 789 SS AV P +L +++++++A ++ K ++ P + +S + Sbjct: 1142 ESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLE 1201 Query: 790 KLEEMGLNLRKDQKKTKKRVSFSEQLFTEE----------AVAGAALLVEGHSSCPQE 837 K + L +K + KK + E++ +EE LL E +S P+E Sbjct: 1202 KDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEE 1259 Score = 42.4 bits (98), Expect = 0.003 Identities = 42/136 (30%), Positives = 56/136 (41%), Gaps = 6/136 (4%) Query: 1031 RLQAPQASVTAPSEQTTEFGIHKP--HLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPG 1088 ++ A QA S Q T G KP L + Q PGP+ ++P PS PG Sbjct: 448 KIPAQQAGPGKTSAQQT--GPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505 Query: 1089 TSLDNPV-PSPS-PSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRK 1146 ++ P P P+ PS P + PS ++ S K +A+ S V G K Sbjct: 506 STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK 565 Query: 1147 PLLQAWVSPSETHPVS 1162 PL VSPS P S Sbjct: 566 PLQPPTVSPSAKQPPS 581 Score = 39.7 bits (91), Expect = 0.019 Identities = 94/419 (22%), Positives = 153/419 (36%), Gaps = 71/419 (16%) Query: 171 GKLKDKIKGKNKDSGSDTASAIIPSTTPSVDSDDESVVK-DKKKKSKIKTLLSKSNLQKT 229 G+L D K SG + +P+ + S + VK KK++ ++KT K L+K Sbjct: 1117 GQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKV 1176 Query: 230 PLSQSMSVLPTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQV 289 + SM +P D ++ES D K +A + K L + Sbjct: 1177 KETLSMEKIP---------------PMVTTDQKQEESKLEKD----KASALQEKKPLPEE 1217 Query: 290 NFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGF 349 +P++E +RS+ LE+ + E K P + S Sbjct: 1218 KKLIPEEE------KIRSEE------------KKPLLEEKKPTPEDKKLLPEAKTSAPEE 1259 Query: 350 RKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGD-- 407 +K L S +A +E EG Q + K LPS P L D Sbjct: 1260 QKHDLLKSQVQIA----EEKLEGRVAPKTVQ---EGKQPQTKMEGLPSGTPQSLPKEDDK 1312 Query: 408 ----LRENMAP---ANSEATKEAKESKKPESRRSSLLSLMTGK-----------KDVAKG 449 ++E P A + + KE + E +S S K D Sbjct: 1313 TTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISS 1372 Query: 450 SEGENPLTVPGREKEGMLMGVKP---GEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFE 506 S GE P +P EK+ +L G+K +++S + + + E +++ Q S+L + Sbjct: 1373 SLGEIPSLIPTDEKD-ILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEK 1431 Query: 507 DVQITEP-EAEPES-KSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSS 563 + T+P E PE K + + S T + + E E + T + S D PSS Sbjct: 1432 SEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSS 1490 Score = 38.5 bits (88), Expect = 0.042 Identities = 98/492 (19%), Positives = 179/492 (36%), Gaps = 49/492 (9%) Query: 188 TASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPTSKPEKVL 247 ++S IIP + VD ++++K L + + ++ Q M + P S P + Sbjct: 2031 SSSFIIPESHEIVDLGTMVTSTEEERK----LLDADAAYEELMKRQQMQLTPGSSPTQAP 2086 Query: 248 LRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLN------QVNFTLPKKEGLSF 301 + +S D D D S ++S + T ST L+ +F+ + E Sbjct: 2087 IGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYV 2146 Query: 302 LGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDS-SPSSSPSPKGFRKKHLFSSTEN 360 R ++++ ++ + Y E E+ + S +PS + S S Sbjct: 2147 TDYTREIQEIIAHESLILT----YSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITT 2202 Query: 361 LAAGS--WKEPAEGGGLSSDRQLSESSTK------DSLKSMTLPSYRPAPLVSGDLRENM 412 L + + + EP + D + SST D + +++ R AP +++ Sbjct: 2203 LDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHI 2262 Query: 413 APANSEATKEAKES--KKPESRRSSLLS--LMTGKKDVAKGSEGE--NPLTVPGREKEGM 466 + S+ ES KPE + +S L+ +KD K ++ E N + + E Sbjct: 2263 VISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRD 2322 Query: 467 LMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPP 526 ++ S +E + A+ ++ S F + E P Sbjct: 2323 KKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPS 2382 Query: 527 ISS-PRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGAD 585 +SS P P+ L++S + P P P P PP P Sbjct: 2383 VSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP--------------LP 2428 Query: 586 TQSSESPSVFSSLSSPIAAPISTSTPI--ESWPLVDRGQAKSEGPPLLPKAELQTESLTP 643 +S P++ +A+P++T+TP+ L +S G LP + T + P Sbjct: 2429 PPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNG---LPVTRICTTAPPP 2485 Query: 644 VPNSGSSVLGSL 655 VP SS+ L Sbjct: 2486 VPPKPSSIPSGL 2497 Score = 38.1 bits (87), Expect = 0.054 Identities = 99/441 (22%), Positives = 158/441 (35%), Gaps = 76/441 (17%) Query: 340 PSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKS-MTLPSY 398 P+++ SP RK+ L SS +G +P G + LS+S T D+ +S LP Sbjct: 73 PAAAESPSMHRKQELDSSHPPKQSGRPPDP----GRPAQPGLSKSRTTDTFRSEQKLPGR 128 Query: 399 RPAPLVSGDLRENMAPANSEATKEAKESKKP----ESRRSSLLSLMTGKK---DVAKGSE 451 P+ + L+E+ + ++ +E K S P E S +S + K D+ SE Sbjct: 129 SPSTI---SLKESKS--RTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSE 183 Query: 452 GENPLTVPGRE----KEGMLMGV----------KPGEDASGPAEDLVRR--SEKDTAAVV 495 T ++ ++G G+ KP GP D +++ + K ++ Sbjct: 184 ASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ 243 Query: 496 SRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTR--------AVKPRLEVSPE 547 + S I P P++ P PQT+ +VKP L SP Sbjct: 244 PEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLP-SP- 301 Query: 548 AQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPIS 607 ++P + P+P P+ P S + P P+ S L+ P+A Sbjct: 302 SKPPIQQPTPGKPPAQQPGHEKSQPGPAKP--------------PAQPSGLTKPLAQQPG 347 Query: 608 TSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGT 667 T P P+ G K PL P ++ + P+S +L + P Sbjct: 348 TVKP----PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ 403 Query: 668 EDS-LMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGE---A 723 + T++ GT K L +QP G Q P K P G+ Sbjct: 404 QPGPAKPPTQQVGTPK---------PLAQQP--GLQSPAKAPGPTKTPVQQPGPGKIPAQ 452 Query: 724 QEVPFALSLSSDGAVSPVGEL 744 Q P S G P +L Sbjct: 453 QAGPGKTSAQQTGPTKPPSQL 473 Score = 37.0 bits (84), Expect = 0.12 Identities = 86/438 (19%), Positives = 139/438 (31%), Gaps = 55/438 (12%) Query: 202 SDDESVVKDKKKKSKI--KTLLSKSNLQKTPLSQSMSVLPTSKPEKVLLRPGDFQSQWDE 259 SD E+ ++ KK K+ K + K PL Q KP PG Q D Sbjct: 180 SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQ-----PPKPIPKQQGPGRDPLQQDG 234 Query: 260 DDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCI 319 S + S ++ Q T K L R + ++ + Sbjct: 235 TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQ-----RDASRPQTKQADIV 289 Query: 320 NGNHVYLEQPE-AKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSD 378 G V P +K I+ +P P+ + +K G K PA+ GL+ Sbjct: 290 RGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKS--------QPGPAKPPAQPSGLTKP 341 Query: 379 RQLSESSTKDSLK--SMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSL 436 + K ++ T P +P + PA A + E KP S + Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPAQP-----------LGPAKPPAQQTGSE--KPSSEQPGP 388 Query: 437 LSLM----TGKKDVAKGSEGENPLTVPGREKE-GMLMGVKPGEDASGPAEDLVRRSEKDT 491 +L GK + + P G K G++ A GP + V++ Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK 448 Query: 492 AAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAP-------------QTRAV 538 + G + T+P ++ ++P P P P Q + Sbjct: 449 IPA-QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST 507 Query: 539 KPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSL 598 KP + A+P+ + P T PS P S Q P++ T+ L Sbjct: 508 KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567 Query: 599 SSPIAAPISTSTPIESWP 616 P +P + P + P Sbjct: 568 QPPTVSPSAKQPPSQGLP 585 Score = 31.2 bits (69), Expect = 6.7 Identities = 33/123 (26%), Positives = 48/123 (39%), Gaps = 27/123 (21%) Query: 1074 EEKPMGNGSPSPP-----PGTSLDNPVPSPSPSE--------IFPVTHSFPSSAHSDTHH 1120 + KPM GSP+PP G ++ P SP P E + +T + P S + Sbjct: 867 DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDA-PKSQPTTPQE 925 Query: 1121 TST-----------AESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPGAGT 1169 T T +++ + G G G P+ QA +PS+ P S P T Sbjct: 926 TVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA-PAPSQP-PTSQGPPKST 983 Query: 1170 GSA 1172 G A Sbjct: 984 GQA 986 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 54.3 bits (129), Expect = 7e-07 Identities = 125/598 (20%), Positives = 215/598 (35%), Gaps = 104/598 (17%) Query: 328 QPEAKGEIKDSSP----SSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSE 383 QP+ KD++P S +P PK + + K+P E LS E Sbjct: 678 QPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKE 737 Query: 384 SSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGK 443 S + +P ++ ++S TK S K +S+ + K Sbjct: 738 PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL-K 796 Query: 444 KDVAKGSEGENPL--TVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSS 501 D AK S+ P V + + + + S P + +K V ++ Sbjct: 797 TDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK 856 Query: 502 LNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTAR-----LPS 556 + +P+A+P K P PP P A QT P + SP+ Q +R L S Sbjct: 857 KA--QTKMSPKPDAKPMPKGSPTPPGPRPTAGQT---VPTPQQSPKPQEQSRRFSLNLGS 911 Query: 557 PTDSPSSLPPLP-----------------------SSSGQASVPSELGHGADTQSSESPS 593 TD+P S P P S++GQ S+ G GA + + +PS Sbjct: 912 ITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPS 971 Query: 594 VFSSLSSPIAAPIST---------STPIE---SWPLVDRGQAKSEGPPLLPKAELQ---- 637 + P P ST S P++ P ++ + K+E P + + E + Sbjct: 972 QPPTSQGP---PKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPP 1028 Query: 638 ----TESLTPVPNSGSSVLGSLFKQPSFP----------ANKGTEDSLMGRT-------- 675 ++SLT P +VL + ++ P N G++D T Sbjct: 1029 PIKDSKSLTAEPQ--KAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQV 1086 Query: 676 -RETGTEKNTSSLELEESLPEQPETGR----QEEELPRFPCKKQDYSPSSGEAQEVPFAL 730 G E++E L +T R Q ++ + P +PS +A +P Sbjct: 1087 CNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP-----PAPSGPKASPMPVPT 1141 Query: 731 SLSSD-GAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMR 789 SS AV P +L +++++++A ++ K ++ P + +S + Sbjct: 1142 ESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLE 1201 Query: 790 KLEEMGLNLRKDQKKTKKRVSFSEQLFTEE----------AVAGAALLVEGHSSCPQE 837 K + L +K + KK + E++ +EE LL E +S P+E Sbjct: 1202 KDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEE 1259 Score = 42.4 bits (98), Expect = 0.003 Identities = 42/136 (30%), Positives = 56/136 (41%), Gaps = 6/136 (4%) Query: 1031 RLQAPQASVTAPSEQTTEFGIHKP--HLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPG 1088 ++ A QA S Q T G KP L + Q PGP+ ++P PS PG Sbjct: 448 KIPAQQAGPGKTSAQQT--GPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505 Query: 1089 TSLDNPV-PSPS-PSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRK 1146 ++ P P P+ PS P + PS ++ S K +A+ S V G K Sbjct: 506 STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK 565 Query: 1147 PLLQAWVSPSETHPVS 1162 PL VSPS P S Sbjct: 566 PLQPPTVSPSAKQPPS 581 Score = 39.7 bits (91), Expect = 0.019 Identities = 94/419 (22%), Positives = 153/419 (36%), Gaps = 71/419 (16%) Query: 171 GKLKDKIKGKNKDSGSDTASAIIPSTTPSVDSDDESVVK-DKKKKSKIKTLLSKSNLQKT 229 G+L D K SG + +P+ + S + VK KK++ ++KT K L+K Sbjct: 1117 GQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKV 1176 Query: 230 PLSQSMSVLPTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQV 289 + SM +P D ++ES D K +A + K L + Sbjct: 1177 KETLSMEKIP---------------PMVTTDQKQEESKLEKD----KASALQEKKPLPEE 1217 Query: 290 NFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGF 349 +P++E +RS+ LE+ + E K P + S Sbjct: 1218 KKLIPEEE------KIRSEE------------KKPLLEEKKPTPEDKKLLPEAKTSAPEE 1259 Query: 350 RKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGD-- 407 +K L S +A +E EG Q + K LPS P L D Sbjct: 1260 QKHDLLKSQVQIA----EEKLEGRVAPKTVQ---EGKQPQTKMEGLPSGTPQSLPKEDDK 1312 Query: 408 ----LRENMAP---ANSEATKEAKESKKPESRRSSLLSLMTGK-----------KDVAKG 449 ++E P A + + KE + E +S S K D Sbjct: 1313 TTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISS 1372 Query: 450 SEGENPLTVPGREKEGMLMGVKP---GEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFE 506 S GE P +P EK+ +L G+K +++S + + + E +++ Q S+L + Sbjct: 1373 SLGEIPSLIPTDEKD-ILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEK 1431 Query: 507 DVQITEP-EAEPES-KSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSS 563 + T+P E PE K + + S T + + E E + T + S D PSS Sbjct: 1432 SEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSS 1490 Score = 38.5 bits (88), Expect = 0.042 Identities = 98/492 (19%), Positives = 179/492 (36%), Gaps = 49/492 (9%) Query: 188 TASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPTSKPEKVL 247 ++S IIP + VD ++++K L + + ++ Q M + P S P + Sbjct: 2031 SSSFIIPESHEIVDLGTMVTSTEEERK----LLDADAAYEELMKRQQMQLTPGSSPTQAP 2086 Query: 248 LRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLN------QVNFTLPKKEGLSF 301 + +S D D D S ++S + T ST L+ +F+ + E Sbjct: 2087 IGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYV 2146 Query: 302 LGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDS-SPSSSPSPKGFRKKHLFSSTEN 360 R ++++ ++ + Y E E+ + S +PS + S S Sbjct: 2147 TDYTREIQEIIAHESLILT----YSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITT 2202 Query: 361 LAAGS--WKEPAEGGGLSSDRQLSESSTK------DSLKSMTLPSYRPAPLVSGDLRENM 412 L + + + EP + D + SST D + +++ R AP +++ Sbjct: 2203 LDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHI 2262 Query: 413 APANSEATKEAKES--KKPESRRSSLLS--LMTGKKDVAKGSEGE--NPLTVPGREKEGM 466 + S+ ES KPE + +S L+ +KD K ++ E N + + E Sbjct: 2263 VISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRD 2322 Query: 467 LMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPP 526 ++ S +E + A+ ++ S F + E P Sbjct: 2323 KKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPS 2382 Query: 527 ISS-PRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGAD 585 +SS P P+ L++S + P P P P PP P Sbjct: 2383 VSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP--------------LP 2428 Query: 586 TQSSESPSVFSSLSSPIAAPISTSTPI--ESWPLVDRGQAKSEGPPLLPKAELQTESLTP 643 +S P++ +A+P++T+TP+ L +S G LP + T + P Sbjct: 2429 PPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNG---LPVTRICTTAPPP 2485 Query: 644 VPNSGSSVLGSL 655 VP SS+ L Sbjct: 2486 VPPKPSSIPSGL 2497 Score = 38.1 bits (87), Expect = 0.054 Identities = 99/441 (22%), Positives = 158/441 (35%), Gaps = 76/441 (17%) Query: 340 PSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKS-MTLPSY 398 P+++ SP RK+ L SS +G +P G + LS+S T D+ +S LP Sbjct: 73 PAAAESPSMHRKQELDSSHPPKQSGRPPDP----GRPAQPGLSKSRTTDTFRSEQKLPGR 128 Query: 399 RPAPLVSGDLRENMAPANSEATKEAKESKKP----ESRRSSLLSLMTGKK---DVAKGSE 451 P+ + L+E+ + ++ +E K S P E S +S + K D+ SE Sbjct: 129 SPSTI---SLKESKS--RTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSE 183 Query: 452 GENPLTVPGRE----KEGMLMGV----------KPGEDASGPAEDLVRR--SEKDTAAVV 495 T ++ ++G G+ KP GP D +++ + K ++ Sbjct: 184 ASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ 243 Query: 496 SRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTR--------AVKPRLEVSPE 547 + S I P P++ P PQT+ +VKP L SP Sbjct: 244 PEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLP-SP- 301 Query: 548 AQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPIS 607 ++P + P+P P+ P S + P P+ S L+ P+A Sbjct: 302 SKPPIQQPTPGKPPAQQPGHEKSQPGPAKP--------------PAQPSGLTKPLAQQPG 347 Query: 608 TSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGT 667 T P P+ G K PL P ++ + P+S +L + P Sbjct: 348 TVKP----PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ 403 Query: 668 EDS-LMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGE---A 723 + T++ GT K L +QP G Q P K P G+ Sbjct: 404 QPGPAKPPTQQVGTPK---------PLAQQP--GLQSPAKAPGPTKTPVQQPGPGKIPAQ 452 Query: 724 QEVPFALSLSSDGAVSPVGEL 744 Q P S G P +L Sbjct: 453 QAGPGKTSAQQTGPTKPPSQL 473 Score = 37.0 bits (84), Expect = 0.12 Identities = 86/438 (19%), Positives = 139/438 (31%), Gaps = 55/438 (12%) Query: 202 SDDESVVKDKKKKSKI--KTLLSKSNLQKTPLSQSMSVLPTSKPEKVLLRPGDFQSQWDE 259 SD E+ ++ KK K+ K + K PL Q KP PG Q D Sbjct: 180 SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQ-----PPKPIPKQQGPGRDPLQQDG 234 Query: 260 DDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCI 319 S + S ++ Q T K L R + ++ + Sbjct: 235 TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQ-----RDASRPQTKQADIV 289 Query: 320 NGNHVYLEQPE-AKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSD 378 G V P +K I+ +P P+ + +K G K PA+ GL+ Sbjct: 290 RGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKS--------QPGPAKPPAQPSGLTKP 341 Query: 379 RQLSESSTKDSLK--SMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSL 436 + K ++ T P +P + PA A + E KP S + Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPAQP-----------LGPAKPPAQQTGSE--KPSSEQPGP 388 Query: 437 LSLM----TGKKDVAKGSEGENPLTVPGREKE-GMLMGVKPGEDASGPAEDLVRRSEKDT 491 +L GK + + P G K G++ A GP + V++ Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK 448 Query: 492 AAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAP-------------QTRAV 538 + G + T+P ++ ++P P P P Q + Sbjct: 449 IPA-QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST 507 Query: 539 KPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSL 598 KP + A+P+ + P T PS P S Q P++ T+ L Sbjct: 508 KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567 Query: 599 SSPIAAPISTSTPIESWP 616 P +P + P + P Sbjct: 568 QPPTVSPSAKQPPSQGLP 585 Score = 31.2 bits (69), Expect = 6.7 Identities = 33/123 (26%), Positives = 48/123 (39%), Gaps = 27/123 (21%) Query: 1074 EEKPMGNGSPSPP-----PGTSLDNPVPSPSPSE--------IFPVTHSFPSSAHSDTHH 1120 + KPM GSP+PP G ++ P SP P E + +T + P S + Sbjct: 867 DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDA-PKSQPTTPQE 925 Query: 1121 TST-----------AESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPGAGT 1169 T T +++ + G G G P+ QA +PS+ P S P T Sbjct: 926 TVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA-PAPSQP-PTSQGPPKST 983 Query: 1170 GSA 1172 G A Sbjct: 984 GQA 986 >gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax homolog 2 [Homo sapiens] Length = 1210 Score = 53.9 bits (128), Expect = 1e-06 Identities = 81/336 (24%), Positives = 125/336 (37%), Gaps = 67/336 (19%) Query: 472 PGEDASGPAEDLVRRSEKDTAAVV---SRQGSSLNLFEDVQITEPEAEPESKSEPRPPIS 528 P +D+ + + + DT++ S+QG+S L +D+Q+++ E ++ +PP S Sbjct: 388 PTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSS 447 Query: 529 SPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQS 588 S +P +P SLP +S+ +S SE +D+ S Sbjct: 448 S--------------------------APPSAPQSLPEPVASAHSSSAESESTSDSDS-S 480 Query: 589 SESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSG 648 S+S S SS S P+ T P PP K +L LT V Sbjct: 481 SDSESESSSSDSEENEPLETPAP-------------EPEPPTTNKWQLD-NWLTKVSQPA 526 Query: 649 SSVLGSLFKQP--SFPANKGTEDSLMGRTR-ETGTEKNTSSLELEESLPEQPETGRQEEE 705 + G +P P +KG+ DS + E+ SS + + PE P G++ Sbjct: 527 APPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRS-- 584 Query: 706 LPRFPCKKQDYSPSSGEAQEV-------PFALSLSSDGAVSPVGELAAG----GDRDLES 754 C+K + Q V P S + S GE G G RD S Sbjct: 585 -----CQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTS 639 Query: 755 QAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRK 790 + V++K R A P P A PS + K Sbjct: 640 KDKPKVKTKGRPRAAASNEPKP--AVPPSSEKKKHK 673 Score = 42.4 bits (98), Expect = 0.003 Identities = 136/646 (21%), Positives = 218/646 (33%), Gaps = 111/646 (17%) Query: 545 SPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAA 604 +P ++ P PT + + + Q S+ T S+ S L + Sbjct: 376 TPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSK------THSNSQQGTSSMLEDDLQL 429 Query: 605 PISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPAN 664 S + E P S PP P++ + PV ++ SS S Sbjct: 430 SDSEDSDSEQTP---EKPPSSSAPPSAPQSLPE-----PVASAHSSSAES---------- 471 Query: 665 KGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQ 724 + T DS + +E +SS + EE+ P ET E E P + Sbjct: 472 ESTSDS----DSSSDSESESSSSDSEENEPL--ETPAPEPE------------PPTTNKW 513 Query: 725 EVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSI 784 ++ L+ S A P G + R GS + +++ +E PP + P Sbjct: 514 QLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRA 573 Query: 785 DSMM-----RKLEEMGLNLRKDQKKT------KKRVSFSEQLFTEEAVAGA---ALLVEG 830 R ++ Q++T KK V S + + ++ G LL G Sbjct: 574 PPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYG 633 Query: 831 HSSCPQELNPAWSVAGN---ASDGEP-PESPHAEDSERESVTTPGPATCGAPASPADHLL 886 + P G A+ EP P P + + ++ + P P+ + PA + Sbjct: 634 SRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNV 693 Query: 887 LPSQEESFSEVPMSEASSAKDTPL-FRMEG-EDALVTQYQSKASDHEGLLSDPLSDLQLV 944 E F+ VP++E+ + R G A+V Q S+ + L PL D +L+ Sbjct: 694 EDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSR----KDRLPLPLRDTKLL 749 Query: 945 SDFK-----SPIMADLNLSLPS-IPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGA 998 S + +M + L L S IP+ R + ED + K S+ Sbjct: 750 SPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSK 809 Query: 999 LSLGLVVPCPERGKGPSGEADRLVLGEGLCD---FRLQAPQASVTAPSEQT-TEFGIHKP 1054 L+ K GEA+R CD RL+ S ++ S + E KP Sbjct: 810 LA-----------KKRKGEAER------DCDNKKIRLEKEIKSQSSSSSSSHKESSKTKP 852 Query: 1055 HLGKSSSLDKQL--PGPSGGEEEKPMGNGSPSPPPGTSLDNPVPSPSPSEIFPVTHSFPS 1112 S S K++ P P +KP P S E P Sbjct: 853 SRPSSQSSKKEMLPPPPVSSSSQKPA--------------KPALKRSRREADTCGQDPPK 898 Query: 1113 SAHS--DTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQAWVSPS 1156 SA S H S+ Q++ +GS E+ G + PS Sbjct: 899 SASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPS 944 >gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo sapiens] Length = 778 Score = 53.1 bits (126), Expect = 2e-06 Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 7/99 (7%) Query: 20 VQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERSLGAPVWREEATFELPSLLS 79 V +T+++ R L+A G SD Y ++G +KY + + ++L P WRE+ F L Sbjct: 251 VSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLN-PQWREQFDFHLYE--- 306 Query: 80 SGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQ 118 + +T + D F+GR +VDL L R+Q Sbjct: 307 ---ERGGVIDITAWDKDAGKRDDFIGRCQVDLSALSREQ 342 Score = 38.5 bits (88), Expect = 0.042 Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 9/96 (9%) Query: 20 VQVTVLQARGLRAKGPGGTSDAYAVIQV-GKEKYATSVSERSLGAPVWREEATFELPSLL 78 + +T+ + + L A+ GGTSD Y ++ GKE + + + ++L PVW E+A + L Sbjct: 42 LDITLRRGQSLAARDRGGTSDPYVKFKIGGKEVFRSKIIHKNLN-PVWEEKACILVDHL- 99 Query: 79 SSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDL 114 L + V D F+G A +DL L Sbjct: 100 ------REPLYIKVFDYDFGLQDDFMGSAFLDLTQL 129 >gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Homo sapiens] Length = 999 Score = 53.1 bits (126), Expect = 2e-06 Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 7/99 (7%) Query: 20 VQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERSLGAPVWREEATFELPSLLS 79 V +T+++ R L+A G SD Y ++G +KY + + ++L P WRE+ F L Sbjct: 472 VSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLN-PQWREQFDFHLYE--- 527 Query: 80 SGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQ 118 + +T + D F+GR +VDL L R+Q Sbjct: 528 ---ERGGVIDITAWDKDAGKRDDFIGRCQVDLSALSREQ 563 Score = 38.5 bits (88), Expect = 0.042 Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 9/96 (9%) Query: 20 VQVTVLQARGLRAKGPGGTSDAYAVIQV-GKEKYATSVSERSLGAPVWREEATFELPSLL 78 + +T+ + + L A+ GGTSD Y ++ GKE + + + ++L PVW E+A + L Sbjct: 263 LDITLRRGQSLAARDRGGTSDPYVKFKIGGKEVFRSKIIHKNLN-PVWEEKACILVDHL- 320 Query: 79 SSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDL 114 L + V D F+G A +DL L Sbjct: 321 ------REPLYIKVFDYDFGLQDDFMGSAFLDLTQL 350 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 52.4 bits (124), Expect = 3e-06 Identities = 100/426 (23%), Positives = 150/426 (35%), Gaps = 38/426 (8%) Query: 240 TSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHK-RTASTDLKQLNQVNFTLPKKEG 298 TS ++ LRP + DE+D E E D+ A D K + E Sbjct: 973 TSSGDQKRLRPS---TSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLEL 1029 Query: 299 LSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSST 358 S GG + + LS E+ E + + D S S L ++ Sbjct: 1030 DS--GGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEAS 1087 Query: 359 ENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSE 418 E S +E E + + + + SS++ S S S +P S D E + E Sbjct: 1088 EKDEGDSDEE--ETVSIVTSKAEATSSSESSESSEFESSSESSPSSSED-EEEVVAREEE 1144 Query: 419 ATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGR---EKEGMLMGVKPGED 475 +E +E ES S+ G +D + +GE PG + GM V + Sbjct: 1145 EEEEEEEMVAEESMASA------GPEDFEQ--DGEEAALAPGAPAVDSLGMEEEVDIETE 1196 Query: 476 ASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEA-----EPESKS-EPRPPISS 529 A P E E V S E+ +++ A EP +K E RPP+S Sbjct: 1197 AVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSP 1256 Query: 530 PRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHG------ 583 RAP+ LEV PE LP P PP P S ++ H Sbjct: 1257 ERAPEHD-----LEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEP 1311 Query: 584 -ADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLT 642 A+ +P + SL+ + +TP PL S P +P + + + Sbjct: 1312 LAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPS 1371 Query: 643 PVPNSG 648 P +SG Sbjct: 1372 PSLSSG 1377 Score = 37.0 bits (84), Expect = 0.12 Identities = 74/318 (23%), Positives = 119/318 (37%), Gaps = 52/318 (16%) Query: 593 SVFSSLSSPIA---APISTSTPIESWPLVDRGQ-AKSEGPPLLPKAELQTESLT------ 642 S FS +P+A P T ++ D G+ ++ PP LP AE + Sbjct: 395 SAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGP 454 Query: 643 PVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRET---GTEKNTSSLELE-ESLPEQPE 698 P P++ S LG +P+F + DS T E+ G EK SL+ E L ++ Sbjct: 455 PPPDTNSMELGG---RPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQR 511 Query: 699 TG----RQEEELPRFPCKKQDYSPSSGEAQEV-PFALSLSSDGAVSPVGELAAGGDRDLE 753 T R+ + + S SS + + PF + S G P + LE Sbjct: 512 TKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTN-SQPGFRGPTPPSSRPSSTGLE 570 Query: 754 SQAGSLVESKARDAAEEVA--PPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVSF 811 + + + D ++ P P P ++ + E+ L+L D+ T +++ Sbjct: 571 DISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMD- 629 Query: 812 SEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPESP-HAEDSERESVTTP 870 EG S +++ SD E P +P + D + V TP Sbjct: 630 -----------------EGQQSSGEDME--------ISDDEMPSAPITSADCPKPMVVTP 664 Query: 871 GPATCGAPASPADHLLLP 888 G A AP+ A L LP Sbjct: 665 GAAAVAAPSVLAPTLPLP 682 Score = 37.0 bits (84), Expect = 0.12 Identities = 43/174 (24%), Positives = 66/174 (37%), Gaps = 20/174 (11%) Query: 412 MAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGML---M 468 +AP + + + P SR SS TG +D++ P +P +++ L + Sbjct: 543 LAPFGTNSQPGFRGPTPPSSRPSS-----TGLEDIS-------PTPLPDSDEDEELDLGL 590 Query: 469 GVKPGEDAS--GPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPP 526 G +P + PA L + +E V R +S + E Q + + E P P Sbjct: 591 GPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAP 650 Query: 527 ISSPRAPQTRAVKP---RLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVP 577 I+S P+ V P + PT LP P P PP P Q P Sbjct: 651 ITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFP 704 Score = 32.7 bits (73), Expect = 2.3 Identities = 46/212 (21%), Positives = 68/212 (32%), Gaps = 19/212 (8%) Query: 376 SSDRQLSE-----SSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATK---EAKESK 427 SS QLS ++++ + T PS RP+ D+ P + E + Sbjct: 535 SSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRP 594 Query: 428 KPESRRSSLLSLMTGKKDVAKGSEGENPLTVP----GREKEGMLMGVKPGEDASGPAEDL 483 PE L++ +VA G+ T G++ G M + E S P Sbjct: 595 PPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSA 654 Query: 484 VRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLE 543 + + L + + P P P PP P P + P Sbjct: 655 DCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPP 714 Query: 544 VSPEAQPTARLPSP-------TDSPSSLPPLP 568 P A P +P P P LPPLP Sbjct: 715 PPPPAHPAVTVPPPPLPAPPGVPPPPILPPLP 746 >gi|31324577 molecule interacting with Rab13 [Homo sapiens] Length = 863 Score = 52.4 bits (124), Expect = 3e-06 Identities = 112/448 (25%), Positives = 150/448 (33%), Gaps = 82/448 (18%) Query: 372 GGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEAT---KEAKESKK 428 GGG SS + P P V G L+E +P T ++A ES Sbjct: 254 GGGPSSSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTT 313 Query: 429 PESR----RSSL----LSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPA 480 P RSSL L G + G E P+ P KP E P Sbjct: 314 PAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTP-------KPSEGTPAPR 366 Query: 481 EDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAP--QTRAV 538 +D IT +AEP+ K P PP SSP P +R V Sbjct: 367 KD------------------------PPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQV 402 Query: 539 K-PRLEVSPEAQPTARLPSPTDSP------SSLPPLPSSSGQASVPSELGHGADTQSSES 591 + E + PTA L S +P P++ A+ P+ LGH T S Sbjct: 403 ENGGTEEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPA-LGHPESTPKSLH 461 Query: 592 PSV-FSSLSSPIAAPISTSTPIESWPLVDRGQ--AKSEGPPLLPKAELQTESLTPVPNSG 648 P + SSP + PL + SE P P L ESL+ S Sbjct: 462 PWYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSATPSPALSVESLS--SESA 519 Query: 649 SSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPE-TGRQEEELP 707 S G+ +P +E ++ GT N SL SL E + E++P Sbjct: 520 SQTAGAELLEPPAVPKSSSEPAV----HAPGTPGNPVSLSTNSSLASSGELVEPRVEQMP 575 Query: 708 ----------RFPCKKQDYSPSSGEAQEVPFAL-----SLSSDGAVSPVGELAAGGDRD- 751 R Q P SG A P L + S G+ SP ++ + + Sbjct: 576 QASPGLAPRTRGSSGPQPAKPCSG-ATPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENP 634 Query: 752 ---LESQAGSLVESKARDAAEEVAPPLP 776 S A S KA ++ V PP P Sbjct: 635 FNRKPSPAASPATKKATKGSKPVRPPAP 662 Score = 37.7 bits (86), Expect = 0.071 Identities = 92/422 (21%), Positives = 141/422 (33%), Gaps = 39/422 (9%) Query: 697 PETGRQEEELPRFPCKKQDY-SPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQ 755 PE Q PR P K Q+ SP +G P S S+ A ++ +L Q Sbjct: 274 PEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQ 333 Query: 756 AGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQL 815 AGS S E+ P P G PS + + + + L + + K KK Sbjct: 334 AGS--SSLVNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPK-KKPAPLPPSS 390 Query: 816 FTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSERESVTTPGPATC 875 + + G + + +P S+ + P ED E E+ P AT Sbjct: 391 SPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYN---PFEEEEEDKEEEAPAAPSLATS 447 Query: 876 GAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLS 935 A P P + + + + K P R L + S+ S E + Sbjct: 448 PALGHPES---TPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLAL-HASRLSHSEPPSA 503 Query: 936 DP---LSDLQLVSDFKSPIMADLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGETAKSS 992 P LS L S+ S L P++P+ +S+ V G + SS Sbjct: 504 TPSPALSVESLSSESASQTAGAELLEPPAVPKSSSEPA----VHAPGTPGNPVSLSTNSS 559 Query: 993 TLDIGALSLGLVVPCPE-------RGKGPSG-EADRLVLGEGLCDFRLQAPQASVTAPSE 1044 G L V P+ R +G SG + + G L ++ V +P Sbjct: 560 LASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGATPTPLLLVGDRSPVPSPGS 619 Query: 1045 QTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDNPVPSPSPSEIF 1104 + + + KSS + KP SP+ T PV P+P F Sbjct: 620 SSPQLQV------KSSCKENPF-------NRKPSPAASPATKKATKGSKPVRPPAPGHGF 666 Query: 1105 PV 1106 P+ Sbjct: 667 PL 668 >gi|222418647 mucin 7, secreted precursor [Homo sapiens] Length = 377 Score = 52.0 bits (123), Expect = 4e-06 Identities = 52/199 (26%), Positives = 84/199 (42%), Gaps = 20/199 (10%) Query: 519 SKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLP-----SPTDSPSSLPPLPSSSGQ 573 S + P PP SS P+T A P + +A P++ P +P P++ P PSS Sbjct: 173 SATTPAPP-SSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSS--- 228 Query: 574 ASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPK 633 S P E T S+ +P+ SS + P + P S +D A + PP Sbjct: 229 -SAPPETTAAPPTPSATTPAPLSSSAPPETTAV---PPTPSATTLDPSSASA--PPETTA 282 Query: 634 AELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETG---TEKNTSSLELE 690 A + TP P S + + + P + T +L T ET T + T+S+ + Sbjct: 283 APPTPSATTPAPPSSPAPQETTAAPITTPNSSPT--TLAPDTSETSAAPTHQTTTSVTTQ 340 Query: 691 ESLPEQPETGRQEEELPRF 709 + +QP + + ++ RF Sbjct: 341 TTTTKQPTSAPGQNKISRF 359 Score = 51.2 bits (121), Expect = 6e-06 Identities = 46/177 (25%), Positives = 75/177 (42%), Gaps = 15/177 (8%) Query: 515 AEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDS-----PSSLPPLPS 569 A PE+ + P P ++ +AP + + P +P P A P+P S ++ PP PS Sbjct: 184 APPETTAAPPTPSATTQAPPSSSAPPETTAAPPT-PPATTPAPPSSSAPPETTAAPPTPS 242 Query: 570 SSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPP 629 A+ P+ L A +++ P + S+ P S S P E+ A + PP Sbjct: 243 ----ATTPAPLSSSAPPETTAVP---PTPSATTLDPSSASAPPETTAAPPTPSATTPAPP 295 Query: 630 LLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSS 686 P + T + PNS + L + S T S+ T+ T T++ TS+ Sbjct: 296 SSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSV--TTQTTTTKQPTSA 350 Score = 36.2 bits (82), Expect = 0.21 Identities = 51/251 (20%), Positives = 82/251 (32%), Gaps = 25/251 (9%) Query: 513 PEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPT--DSPSSLPPLPSS 570 P+ P + P+ P +P P K V+P T ++PS T + + + LP+ Sbjct: 72 PKLPPSPNNPPKFP--NPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNV 129 Query: 571 SGQASVPSELGHGADTQSSESPSVFSSLSSPIA---------------APISTSTPIESW 615 + + + + +S S + + ++SP AP S+S P E+ Sbjct: 130 TFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETT 189 Query: 616 PLVDRGQA------KSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTED 669 A S PP A + TP P S S+ + P+ A Sbjct: 190 AAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPL 249 Query: 670 SLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFA 729 S T S+ L+ S P P SP+ E P Sbjct: 250 SSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPIT 309 Query: 730 LSLSSDGAVSP 740 SS ++P Sbjct: 310 TPNSSPTTLAP 320 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 52.0 bits (123), Expect = 4e-06 Identities = 108/485 (22%), Positives = 168/485 (34%), Gaps = 63/485 (12%) Query: 335 IKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMT 394 I +S+P + P+ + +S+ N A+ + PA G G + + S S Sbjct: 70 IPESAPRAGPT------RSAGTSSRNPAS---RPPASGRGERAPPAKNTSPGPVSSPGRA 120 Query: 395 LPSYRPAPLVSGDLRENMAP--ANSEATKEAKESKKPESRRSSLLSLMTG-------KKD 445 + RP PL LR + A +AT+ K S R G ++ Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180 Query: 446 VAKGSEGENPLTVPGREK----EGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSS 501 A G+E P P EG V + S R + R S Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240 Query: 502 LNLFEDVQITEP-EAEPESKSEPRPPI--SSPRAPQTRAVKP------RLEVSPEAQPTA 552 ++ P + P ++ PR P S P+ +A++P R + +P P + Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300 Query: 553 RLPSPTDSPSSL---PPLPSSSGQASVPSELGHGADTQ--------SSESPSVFSSLSSP 601 P T SPS P P + +P+ L S +P +L SP Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360 Query: 602 IAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPN-------SGSSVLGS 654 A P S + P + P + + PP+ L + SL P+ ++ LGS Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS 420 Query: 655 LFKQPSFP----ANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFP 710 Q + + + T+ SL +R T ++ L+ SLP P P Sbjct: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASP---------PLQT 471 Query: 711 CKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEE 770 SP S P +LSS + SP L++ LE+Q+ S A Sbjct: 472 SLSPAVSPLSSPLTIHPLQ-ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL 530 Query: 771 VAPPL 775 PPL Sbjct: 531 TTPPL 535 Score = 41.2 bits (95), Expect = 0.006 Identities = 68/253 (26%), Positives = 85/253 (33%), Gaps = 29/253 (11%) Query: 515 AEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLP-----SPTDSPSSLPPLPS 569 A P + P PP S P +P A P P A P ++P SP SPS+ PP Sbjct: 700 AAPPLQVPPSPPASPPMSPS--ATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757 Query: 570 SSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTP----IESWPLVDRGQAKS 625 A+ P ++ SP P AP + +TP + S P GQA Sbjct: 758 PPLLAAPPLQVPPSPPASLPMSPLA----KPPPQAPPALATPPLQALPSPPASFPGQA-- 811 Query: 626 EGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQ--PSFPANKGTEDSLMGRTRETGTEKN 683 P P A L L P VL + Q PS PA+ + T T + Sbjct: 812 ---PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS 868 Query: 684 TSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGE 743 L L + P R P D + S A P L G P G Sbjct: 869 GPRLTLALAPGPPPPPSRS----PSSTLSGPDLAGHSSSATSTPEELRGYDSG---PEGG 921 Query: 744 LAAGGDRDLESQA 756 AA D E A Sbjct: 922 AAASPPPDAELAA 934 Score = 39.3 bits (90), Expect = 0.024 Identities = 36/149 (24%), Positives = 51/149 (34%), Gaps = 10/149 (6%) Query: 521 SEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSEL 580 S P P SP A P L P P + SP SPS+ PP + A+ P ++ Sbjct: 678 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQV 737 Query: 581 GHGADTQSSESPSVFSSLSSPIAAPISTSTPIE-------SWPLVDRGQAKSEGPPLLPK 633 SP S+ P P+ + P++ S P+ + + PP L Sbjct: 738 PPSPPASPPMSP---SATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALAT 794 Query: 634 AELQTESLTPVPNSGSSVLGSLFKQPSFP 662 LQ P G + P P Sbjct: 795 PPLQALPSPPASFPGQAPFSPSASLPMSP 823 Score = 36.6 bits (83), Expect = 0.16 Identities = 41/154 (26%), Positives = 59/154 (38%), Gaps = 29/154 (18%) Query: 513 PEAEPESKSEPR---PPISSPRA-PQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLP 568 P A P ++ P PP+ +P + P + + P SP+A P A +P S PP P Sbjct: 613 PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQA-PNALAVHLLQAPFSPPPSP 671 Query: 569 SSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGP 628 S P+ SP V S + P AP S + P PL + P Sbjct: 672 PVQAPFSPPA------------SPPVSPSATPPSQAPPSLAAP----PL--------QVP 707 Query: 629 PLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFP 662 P P + + S TP P + + + P P Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741 Score = 33.5 bits (75), Expect = 1.3 Identities = 79/317 (24%), Positives = 114/317 (35%), Gaps = 53/317 (16%) Query: 377 SDRQLSESSTKDSLKSMTLPSYRP--APL---VSGDLRENMAPANSEATK-------EAK 424 S RQ S T S + T P P APL S L+ +++PA S + +A Sbjct: 433 SPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL 492 Query: 425 ESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLV 484 S S ++ L SL + E ++ L P + P + P E+L Sbjct: 493 SSLASHSPQAPLSSL------IMPPLETQSSLAPPSLQ-------TPPASLTTPPLENL- 538 Query: 485 RRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSP--RAPQTRAVKPRL 542 + A Q +S L T P P P P+++P P + A P Sbjct: 539 -----PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593 Query: 543 EVSPEAQPTAR-LPSPTDSPSSLPP--------LPSSSGQASVP-SELGHGADTQSSESP 592 A P + LPSP SP + PP LP S P S T S ++P Sbjct: 594 APPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP 653 Query: 593 SVFS--SLSSPIAAPISTS-----TPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVP 645 + + L +P + P S +P S P+ S+ PP L LQ + P P Sbjct: 654 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ---VPPSP 710 Query: 646 NSGSSVLGSLFKQPSFP 662 + + S P P Sbjct: 711 PASPPMSPSATPPPQAP 727 Score = 32.0 bits (71), Expect = 3.9 Identities = 42/154 (27%), Positives = 61/154 (39%), Gaps = 28/154 (18%) Query: 513 PEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPS--- 569 P A P ++ RPP P T PRL ++ P P P+ SPSS P Sbjct: 846 PPASPTLQAPRRPPTPGP---DTSVSGPRLTLALAPGPP---PPPSRSPSSTLSGPDLAG 899 Query: 570 -SSGQASVPSEL---GHGADTQSSESPSVFSSLSS------------PIAAPISTSTPIE 613 SS S P EL G + ++ SP + L++ P+A + P+ Sbjct: 900 HSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL- 958 Query: 614 SWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNS 647 WP G ++G + + E ES TP P + Sbjct: 959 PWPPA-TGPGSADGLCTIYETE-GPESATPAPGA 990 >gi|222418649 mucin 7, secreted precursor [Homo sapiens] Length = 377 Score = 52.0 bits (123), Expect = 4e-06 Identities = 52/199 (26%), Positives = 84/199 (42%), Gaps = 20/199 (10%) Query: 519 SKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLP-----SPTDSPSSLPPLPSSSGQ 573 S + P PP SS P+T A P + +A P++ P +P P++ P PSS Sbjct: 173 SATTPAPP-SSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSS--- 228 Query: 574 ASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPK 633 S P E T S+ +P+ SS + P + P S +D A + PP Sbjct: 229 -SAPPETTAAPPTPSATTPAPLSSSAPPETTAV---PPTPSATTLDPSSASA--PPETTA 282 Query: 634 AELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETG---TEKNTSSLELE 690 A + TP P S + + + P + T +L T ET T + T+S+ + Sbjct: 283 APPTPSATTPAPPSSPAPQETTAAPITTPNSSPT--TLAPDTSETSAAPTHQTTTSVTTQ 340 Query: 691 ESLPEQPETGRQEEELPRF 709 + +QP + + ++ RF Sbjct: 341 TTTTKQPTSAPGQNKISRF 359 Score = 51.2 bits (121), Expect = 6e-06 Identities = 46/177 (25%), Positives = 75/177 (42%), Gaps = 15/177 (8%) Query: 515 AEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDS-----PSSLPPLPS 569 A PE+ + P P ++ +AP + + P +P P A P+P S ++ PP PS Sbjct: 184 APPETTAAPPTPSATTQAPPSSSAPPETTAAPPT-PPATTPAPPSSSAPPETTAAPPTPS 242 Query: 570 SSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPP 629 A+ P+ L A +++ P + S+ P S S P E+ A + PP Sbjct: 243 ----ATTPAPLSSSAPPETTAVP---PTPSATTLDPSSASAPPETTAAPPTPSATTPAPP 295 Query: 630 LLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSS 686 P + T + PNS + L + S T S+ T+ T T++ TS+ Sbjct: 296 SSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSV--TTQTTTTKQPTSA 350 Score = 36.2 bits (82), Expect = 0.21 Identities = 51/251 (20%), Positives = 82/251 (32%), Gaps = 25/251 (9%) Query: 513 PEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPT--DSPSSLPPLPSS 570 P+ P + P+ P +P P K V+P T ++PS T + + + LP+ Sbjct: 72 PKLPPSPNNPPKFP--NPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNV 129 Query: 571 SGQASVPSELGHGADTQSSESPSVFSSLSSPIA---------------APISTSTPIESW 615 + + + + +S S + + ++SP AP S+S P E+ Sbjct: 130 TFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETT 189 Query: 616 PLVDRGQA------KSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTED 669 A S PP A + TP P S S+ + P+ A Sbjct: 190 AAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPL 249 Query: 670 SLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFA 729 S T S+ L+ S P P SP+ E P Sbjct: 250 SSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPIT 309 Query: 730 LSLSSDGAVSP 740 SS ++P Sbjct: 310 TPNSSPTTLAP 320 >gi|222418645 mucin 7, secreted precursor [Homo sapiens] Length = 377 Score = 52.0 bits (123), Expect = 4e-06 Identities = 52/199 (26%), Positives = 84/199 (42%), Gaps = 20/199 (10%) Query: 519 SKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLP-----SPTDSPSSLPPLPSSSGQ 573 S + P PP SS P+T A P + +A P++ P +P P++ P PSS Sbjct: 173 SATTPAPP-SSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSS--- 228 Query: 574 ASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPK 633 S P E T S+ +P+ SS + P + P S +D A + PP Sbjct: 229 -SAPPETTAAPPTPSATTPAPLSSSAPPETTAV---PPTPSATTLDPSSASA--PPETTA 282 Query: 634 AELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETG---TEKNTSSLELE 690 A + TP P S + + + P + T +L T ET T + T+S+ + Sbjct: 283 APPTPSATTPAPPSSPAPQETTAAPITTPNSSPT--TLAPDTSETSAAPTHQTTTSVTTQ 340 Query: 691 ESLPEQPETGRQEEELPRF 709 + +QP + + ++ RF Sbjct: 341 TTTTKQPTSAPGQNKISRF 359 Score = 51.2 bits (121), Expect = 6e-06 Identities = 46/177 (25%), Positives = 75/177 (42%), Gaps = 15/177 (8%) Query: 515 AEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDS-----PSSLPPLPS 569 A PE+ + P P ++ +AP + + P +P P A P+P S ++ PP PS Sbjct: 184 APPETTAAPPTPSATTQAPPSSSAPPETTAAPPT-PPATTPAPPSSSAPPETTAAPPTPS 242 Query: 570 SSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPP 629 A+ P+ L A +++ P + S+ P S S P E+ A + PP Sbjct: 243 ----ATTPAPLSSSAPPETTAVP---PTPSATTLDPSSASAPPETTAAPPTPSATTPAPP 295 Query: 630 LLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSS 686 P + T + PNS + L + S T S+ T+ T T++ TS+ Sbjct: 296 SSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSV--TTQTTTTKQPTSA 350 Score = 36.2 bits (82), Expect = 0.21 Identities = 51/251 (20%), Positives = 82/251 (32%), Gaps = 25/251 (9%) Query: 513 PEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPT--DSPSSLPPLPSS 570 P+ P + P+ P +P P K V+P T ++PS T + + + LP+ Sbjct: 72 PKLPPSPNNPPKFP--NPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNV 129 Query: 571 SGQASVPSELGHGADTQSSESPSVFSSLSSPIA---------------APISTSTPIESW 615 + + + + +S S + + ++SP AP S+S P E+ Sbjct: 130 TFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETT 189 Query: 616 PLVDRGQA------KSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQPSFPANKGTED 669 A S PP A + TP P S S+ + P+ A Sbjct: 190 AAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPL 249 Query: 670 SLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFA 729 S T S+ L+ S P P SP+ E P Sbjct: 250 SSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPIT 309 Query: 730 LSLSSDGAVSP 740 SS ++P Sbjct: 310 TPNSSPTTLAP 320 >gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] Length = 2968 Score = 52.0 bits (123), Expect = 4e-06 Identities = 103/486 (21%), Positives = 163/486 (33%), Gaps = 61/486 (12%) Query: 426 SKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVR 485 S K SR++S KD +G +G G +PG A G Sbjct: 2299 SAKRRSRKTS--------KDTGEGKDG------------GTAGSEEPGAKARGRGRKPSA 2338 Query: 486 RSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISS--------PRAPQTRA 537 +++ D AA + + + EP + P SK P P+ P PQ Sbjct: 2339 KAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSP 2398 Query: 538 VKPRLEVSPEAQPTARLPSPTDS--PSSLPPLPSS---SGQASVPSELGHGADTQSSESP 592 P P +P A LP+P S P+ L +P++ +A E G + E Sbjct: 2399 APPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEA 2458 Query: 593 SVFSSLS-SPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSV 651 + L + +P S D G G PK+ L S P +GSS Sbjct: 2459 ELLVKLDHEGVTSPKSKKAKEALLLREDPG----AGGWQEPKSLLSLGSYPPA--AGSS- 2511 Query: 652 LGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEES-LPEQPETGRQEEELPRFP 710 +P P K T+ L +E G L E+S P+ P+ + E++ Sbjct: 2512 ------EPKAPWPKATDGDL---AQEPG-----PGLTFEDSGNPKSPDKAQAEQDGAEE- 2556 Query: 711 CKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEE 770 + S SSG + + S S+ G+ G + S S+A A Sbjct: 2557 -SESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASS 2615 Query: 771 VAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEG 830 + +S S S + + S S + + + ++ + Sbjct: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDE 2675 Query: 831 HSSC--PQELNPAWSVAGNASDGEPPESPHAEDSERESVTTPGPAT-CGAPASPADHLLL 887 SSC E PA + +A P ++ R S +PG T P +P Sbjct: 2676 DSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQ 2735 Query: 888 PSQEES 893 P Q ++ Sbjct: 2736 PLQPKA 2741 Score = 42.0 bits (97), Expect = 0.004 Identities = 63/296 (21%), Positives = 98/296 (33%), Gaps = 28/296 (9%) Query: 345 SPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLV 404 SPK + K E+ AG W+EP L S + SS P Sbjct: 2471 SPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSE---------PKAPWPKAT 2521 Query: 405 SGDLRENMAPA-NSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREK 463 GDL + P E + K K ++ + + + S + + G E Sbjct: 2522 DGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSET 2581 Query: 464 EGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEP 523 EG G K G+ G R ++ S SS + + + S S Sbjct: 2582 EGEEEGDKNGDGGCGTGG---RNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSS 2638 Query: 524 RPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSL--------PPLPSSSGQAS 575 SS + + + S + ++ S TD SS P S QA+ Sbjct: 2639 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAA 2698 Query: 576 VPSELGH--GADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPP 629 +P++ G S+ SP + P A P P + PL + QA ++ P Sbjct: 2699 LPTKATKQAGKARPSAHSPGKKTPAPQPQAPP-----PQPTQPLQPKAQAGAKSRP 2749 Score = 38.1 bits (87), Expect = 0.054 Identities = 44/234 (18%), Positives = 85/234 (36%), Gaps = 19/234 (8%) Query: 320 NGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDR 379 +GN ++ +A+ + + S SSS S G SS+ + ++GS E E G + D Sbjct: 2538 SGNPKSPDKAQAEQDGAEESESSSSSSSGSSS----SSSSSSSSGSETEGEEEGDKNGDG 2593 Query: 380 QLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSL 439 S S S PA S + + ++S ++ + S S SS S Sbjct: 2594 GCGTGGRNCSAASSRAAS--PASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2651 Query: 440 MTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQG 499 + + S + + +++ +D + PA ++ ++Q Sbjct: 2652 SSSSSSSSSSSSSSSSSSSSTTDEDSSCSS----DDEAAPAPTAGPSAQAALPTKATKQA 2707 Query: 500 SSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTAR 553 P A K P P +P T+ ++P+ + +++P R Sbjct: 2708 GK---------ARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKR 2752 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.306 0.125 0.347 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 56,464,500 Number of Sequences: 37866 Number of extensions: 3215929 Number of successful extensions: 18893 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 118 Number of HSP's successfully gapped in prelim test: 1174 Number of HSP's that attempted gapping in prelim test: 13639 Number of HSP's gapped (non-prelim): 5593 length of query: 1283 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1169 effective length of database: 13,930,794 effective search space: 16285098186 effective search space used: 16285098186 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (22.0 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.