Search of human proteins with 5031815

Search of human proteins with 5031815

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5031815 lysyl-tRNA synthetase isoform 2 [Homo sapiens]
         (597 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5031815 lysyl-tRNA synthetase isoform 2 [Homo sapiens]            1209   0.0  
gi|194272210 lysyl-tRNA synthetase isoform 1 [Homo sapiens]          1171   0.0  
gi|45439306 aspartyl-tRNA synthetase [Homo sapiens]                    81   3e-15
gi|40789249 aspartyl-tRNA synthetase 2, mitochondrial [Homo sapi...    75   2e-13
gi|226491502 asparaginyl-tRNA synthetase 2, mitochondrial [Homo ...    46   1e-04
gi|4758762 asparaginyl-tRNA synthetase [Homo sapiens]                  44   3e-04
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi...    35   0.26 
gi|34101288 cleavage and polyadenylation specific factor 2 [Homo...    34   0.44 
gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo ...    33   0.57 
gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo s...    33   0.57 
gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo ...    33   0.57 
gi|54873624 eukaryotic translation initiation factor 2A [Homo sa...    33   0.75 
gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapi...    32   1.3  
gi|153791707 sorting nexin family member 30 [Homo sapiens]             32   1.3  
gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo s...    32   2.2  
gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo s...    32   2.2  
gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]            32   2.2  
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    32   2.2  
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    32   2.2  
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    32   2.2  
gi|116642889 cyclic nucleotide gated channel beta 3 [Homo sapiens]     32   2.2  
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    32   2.2  
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]           31   2.8  
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa...    31   2.8  
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ...    31   2.8  
gi|47419936 SFRS protein kinase 1 [Homo sapiens]                       31   3.7  
gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens]    31   3.7  
gi|51093834 hypothetical protein LOC126859 isoform 2 [Homo sapiens]    31   3.7  
gi|142976783 PDZ domain containing RING finger 4 [Homo sapiens]        31   3.7  
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          31   3.7  

>gi|5031815 lysyl-tRNA synthetase isoform 2 [Homo sapiens]
          Length = 597

 Score = 1209 bits (3127), Expect = 0.0
 Identities = 597/597 (100%), Positives = 597/597 (100%)

Query: 1   MAAVQAAEVKVDGSEPKLSKNELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTT 60
           MAAVQAAEVKVDGSEPKLSKNELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTT
Sbjct: 1   MAAVQAAEVKVDGSEPKLSKNELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTT 60

Query: 61  DNGVGPEEESVDPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDH 120
           DNGVGPEEESVDPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDH
Sbjct: 61  DNGVGPEEESVDPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDH 120

Query: 121 LTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGD 180
           LTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGD
Sbjct: 121 LTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGD 180

Query: 181 IIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFV 240
           IIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFV
Sbjct: 181 IIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFV 240

Query: 241 RQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAP 300
           RQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAP
Sbjct: 241 RQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAP 300

Query: 301 ELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSG 360
           ELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSG
Sbjct: 301 ELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSG 360

Query: 361 MVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETR 420
           MVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETR
Sbjct: 361 MVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETR 420

Query: 421 KILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKE 480
           KILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKE
Sbjct: 421 KILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKE 480

Query: 481 GLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYG 540
           GLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYG
Sbjct: 481 GLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYG 540

Query: 541 LPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGTSV 597
           LPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGTSV
Sbjct: 541 LPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGTSV 597


>gi|194272210 lysyl-tRNA synthetase isoform 1 [Homo sapiens]
          Length = 625

 Score = 1171 bits (3030), Expect = 0.0
 Identities = 576/578 (99%), Positives = 578/578 (100%)

Query: 20  KNELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEESVDPNQYYKI 79
           ++ELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEESVDPNQYYKI
Sbjct: 48  RSELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEESVDPNQYYKI 107

Query: 80  RSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASG 139
           RSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASG
Sbjct: 108 RSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASG 167

Query: 140 GKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSII 199
           GKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSII
Sbjct: 168 GKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSII 227

Query: 200 PYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLD 259
           PYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLD
Sbjct: 228 PYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLD 287

Query: 260 ELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIG 319
           ELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIG
Sbjct: 288 ELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIG 347

Query: 320 RQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPE 379
           RQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPE
Sbjct: 348 RQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPE 407

Query: 380 GQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRT 439
           GQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRT
Sbjct: 408 GQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRT 467

Query: 440 TARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAY 499
           TARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAY
Sbjct: 468 TARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAY 527

Query: 500 TELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLT 559
           TELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLT
Sbjct: 528 TELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLT 587

Query: 560 DSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGTSV 597
           DSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGTSV
Sbjct: 588 DSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGTSV 625


>gi|45439306 aspartyl-tRNA synthetase [Homo sapiens]
          Length = 501

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 106/475 (22%), Positives = 193/475 (40%), Gaps = 64/475 (13%)

Query: 123 DITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDII 182
           D  + V  R+H  RA G K  F  LR +   +Q +    ++ S++  +     + +  I+
Sbjct: 57  DEVVWVRARVHTSRAKG-KQCFLVLRQQQFNVQALVAVGDHASKQ-MVKFAANINKESIV 114

Query: 183 GVQGNPGKTKKGELSIIPYEITLLSPCLHML----PHLHFGLKD---------------- 222
            V+G   K  +   S    ++ L    ++++    P L   L D                
Sbjct: 115 DVEGVVRKVNQKIGSCTQQDVELHVQKIYVISLAEPRLPLQLDDAVRPEAEGEEEGRATV 174

Query: 223 -KETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAK 281
            ++TR   R +DL  +   +  F ++S I    R  L   GF+EI+TP +        A 
Sbjct: 175 NQDTRLDNRVIDLRTSTS-QAVFRLQSGICHLFRETLINKGFVEIQTPKIISAASEGGAN 233

Query: 282 PF-ITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDL-THNPEFTTCE 339
            F ++Y      N Y+  +P+LY +M +    ++V+ IG  FR E  +   H  EF   +
Sbjct: 234 VFTVSYFKN---NAYLAQSPQLYKQMCICADFEKVFSIGPVFRAEDSNTHRHLTEFVGLD 290

Query: 340 FYMAYA-DYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVE 398
             MA+   YH++ME     +  + K +   ++        +       F  P  R+   E
Sbjct: 291 IEMAFNYHYHEVMEEIADTMVQIFKGLQERFQTEIQTVNKQFPCEPFKFLEPTLRLEYCE 350

Query: 399 ELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCIN 458
               AL M L E  +   +E     DD+                  +KL+G  ++     
Sbjct: 351 ----ALAM-LREAGVEMGDE-----DDLSTPN--------------EKLLGHLVKEKYDT 386

Query: 459 PTFICD-HPQIMSPLAKWHRSKEGL-TERFELFVMKKEICNAYTELNDPMRQRQLFEEQA 516
             +I D +P  + P       +    +  +++F+  +EI +    ++DP    QL  E+A
Sbjct: 387 DFYILDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILSGAQRIHDP----QLLTERA 442

Query: 517 KAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFP 571
                  ++     ++F     +G PP AG G+G++RV M     +N+++  +FP
Sbjct: 443 LHHGIDLEKIKAYIDSF----RFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFP 493


>gi|40789249 aspartyl-tRNA synthetase 2, mitochondrial [Homo
           sapiens]
          Length = 645

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 56/178 (31%), Positives = 94/178 (52%), Gaps = 9/178 (5%)

Query: 185 QGNPGKTKKGELSIIPYEITLLSPCLHMLPHL-HFGLKDKETRYRQRYLDLILNDFVRQK 243
           Q NP K   GE+ I      LL+ C  +   + +F  K +  R + RYLDL    F  Q 
Sbjct: 129 QENP-KMPTGEIEIKVKTAELLNACKKLPFEIKNFVKKTEALRLQYRYLDL--RSFQMQY 185

Query: 244 FI-IRSKIITYIRSFLDEL-GFLEIETP-MMNIIPGGAVAKPFITYHNELDMNLYMRIAP 300
            + +RS+++  +R +L  L GF++IETP +    PGGA  K F+    E      +  +P
Sbjct: 186 NLRLRSQMVMKMREYLCNLHGFVDIETPTLFKRTPGGA--KEFLVPSREPGKFYSLPQSP 243

Query: 301 ELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMV 358
           + + ++L+VGG+DR +++ R +R+EG      PEFT  +  M++ D   +  + E ++
Sbjct: 244 QQFKQLLMVGGLDRYFQVARCYRDEGSRPDRQPEFTQIDIEMSFVDQTGIQSLIEGLL 301



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 9/119 (7%)

Query: 453 EVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLF 512
           E+   +  F   HP  +  L  +   K+  ++ ++L +   EI      +++   QR + 
Sbjct: 496 ELESAHHPFTAPHPSDIHLL--YTEPKKARSQHYDLVLNGNEIGGGSIRIHNAELQRYIL 553

Query: 513 EEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFP 571
               K     +D  M    +   AL+YG PP  G  +G+DR+   +T S +I++V+ FP
Sbjct: 554 ATLLK-----EDVKML--SHLLQALDYGAPPHGGIALGLDRLICLVTGSPSIRDVIAFP 605


>gi|226491502 asparaginyl-tRNA synthetase 2, mitochondrial [Homo
           sapiens]
          Length = 477

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 97/469 (20%), Positives = 170/469 (36%), Gaps = 86/469 (18%)

Query: 149 GEGVKLQVMANSRNYKSEEEFIHINN------------------KLRRGDIIGVQGNPGK 190
           GE +K+Q    S   + E  F+H+N+                  +L  G  + VQG   K
Sbjct: 41  GERIKIQGWIRSVRSQKEVLFLHVNDGSSLESLQVVADSGLDSRELNFGSSVEVQGQLIK 100

Query: 191 T--KKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQK----- 243
           +  K+  + +   +I ++  C           KD   +Y++R+    L  +   +     
Sbjct: 101 SPSKRQNVELKAEKIKVIGNC---------DAKDFPIKYKERHPLEYLRQYPHFRCRTNV 151

Query: 244 ----FIIRSKIITYIRSFLDELGFLEIETP------------MMNIIPGGAVAKPFITYH 287
                 IRS+    I SF  + GF+ I TP            +  + P G +  P     
Sbjct: 152 LGSILRIRSEATAAIHSFFKDSGFVHIHTPIITSNDSEGAGELFQLEPSGKLKVP---EE 208

Query: 288 NELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGI-DLTHNPEFTTCEFYMAYAD 346
           N  ++  ++ ++ +L H  ++ G   +V+  G  FR E      H  EF   E  +++ D
Sbjct: 209 NFFNVPAFLTVSGQL-HLEVMSGAFTQVFTFGPTFRAENSQSRRHLAEFYMIEAEISFVD 267

Query: 347 -YHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALG 405
              DLM++ E++       +            PE    DV+    F      + LE  L 
Sbjct: 268 SLQDLMQVIEELFKATTMMVLSKC--------PE----DVELCHKFIAPGQKDRLEHMLK 315

Query: 406 MKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCIN-PTFICD 464
                 +  E  E  K                RT          ++L   C N P F+ +
Sbjct: 316 NNFLIISYTEAVEILKQASQNFTFTPEWGADLRTEHE-------KYLVKHCGNIPVFVIN 368

Query: 465 HPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTEL--NDPMRQRQLFEEQAKAKAAG 522
           +P  + P   + R  E   +     V    +     EL       +R  F E+  A++  
Sbjct: 369 YPLTLKPF--YMRDNEDGPQHTVAAV--DLLVPGVGELFGGGLREERYHFLEERLARSGL 424

Query: 523 DDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFP 571
            +    + + +     +G  P  G+GMG +R    +   +NIK+V+ FP
Sbjct: 425 TE----VYQWYLDLRRFGSVPHGGFGMGFERYLQCILGVDNIKDVIPFP 469


>gi|4758762 asparaginyl-tRNA synthetase [Homo sapiens]
          Length = 548

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 104/465 (22%), Positives = 177/465 (38%), Gaps = 71/465 (15%)

Query: 126 LKVAGRIHAKRASGGKLIFYDLR-GEGVKLQVMANSRNYKSEEEFIHINNK--LRRGDII 182
           +KV G +H  R  G  L+F  LR G G    V+A        +E     N   L     +
Sbjct: 128 VKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLA--------DELCQCYNGVLLSTESSV 179

Query: 183 GVQGNPGKTKKG-------ELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLI 235
            V G    T KG       ELS   +E+  L+P      +L     D + +   R++ +I
Sbjct: 180 AVYGMLNLTPKGKQAPGGHELSCDFWELIGLAPA-GGADNLINEESDVDVQLNNRHM-MI 237

Query: 236 LNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMM--NIIPGGAVAKPFITYHNELDMN 293
             + + +    RS +    R    + G+ E+  P +    + GGA       +  E    
Sbjct: 238 RGENMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFKLDYFGEEA--- 294

Query: 294 LYMRIAPELYHKMLVVGGIDRVYEIGRQFRNE-GIDLTHNPEFTTCEFYMAYADYHDLME 352
            ++  + +LY +  +   +  V+ I + +R E      H  E+T  E    +  + DL+ 
Sbjct: 295 -FLTQSSQLYLETCLPA-LGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFLTFDDLLN 352

Query: 353 ITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTP---PFRRINMVEELE--KALGMK 407
             E +V  +V  I  S      P G      + +F P   PF+R+N  + +   K   +K
Sbjct: 353 RLEDLVCDVVDRILKS------PAGSIVHELNPNFQPPKRPFKRMNYSDAIVWLKEHDVK 406

Query: 408 LPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHP- 466
             +   +E  E      DI          P    RL+   + E        P  +C  P 
Sbjct: 407 KEDGTFYEFGE------DI----------PEAPERLMTDTINE--------PILLCRFPV 442

Query: 467 QIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEA 526
           +I S   +       LTE  ++ +      N    +   MR     E  A  K  G D  
Sbjct: 443 EIKSFYMQRCPEDSRLTESVDVLMP-----NVGEIVGGSMRIFDSEEILAGYKREGIDPT 497

Query: 527 MFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFP 571
            +    +    +YG  P  G+G+G++R   ++ +  +I++V L+P
Sbjct: 498 PYY--WYTDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVCLYP 540


>gi|195976782 Paf1/RNA polymerase II complex component [Homo
           sapiens]
          Length = 710

 Score = 34.7 bits (78), Expect = 0.26
 Identities = 21/83 (25%), Positives = 42/83 (50%), Gaps = 3/83 (3%)

Query: 10  KVDGSEPKLSKNELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEE 69
           +++  E    + E+K++LK  KK  +KE K+K+  E++  + T    +  T +    +E 
Sbjct: 211 RIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHN---KER 267

Query: 70  SVDPNQYYKIRSQAIHQLKVNGE 92
               ++    +SQA+ +LK   E
Sbjct: 268 RSKRDEKLDKKSQAMEELKAERE 290


>gi|34101288 cleavage and polyadenylation specific factor 2 [Homo
           sapiens]
          Length = 782

 Score = 33.9 bits (76), Expect = 0.44
 Identities = 24/89 (26%), Positives = 46/89 (51%), Gaps = 10/89 (11%)

Query: 7   AEVKVDGSEPKLSKNELKRRLKAEKKVAE---KEAKQKELSEKQLSQATAAATNHTTDNG 63
           A   +D    K+++ EL++R+K E K  E   ++ K K+ + K+L Q+  A  + + ++ 
Sbjct: 365 ARFLIDNPSEKITEIELRKRVKLEGKELEEYLEKEKLKKEAAKKLEQSKEADIDSSDESD 424

Query: 64  VGPEEESVDPNQYYKIRSQAIHQLKVNGE 92
           +   EE +D    +K +    H L + GE
Sbjct: 425 I---EEDIDQPSAHKTK----HDLMMKGE 446


>gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo
          sapiens]
          Length = 1723

 Score = 33.5 bits (75), Expect = 0.57
 Identities = 17/41 (41%), Positives = 27/41 (65%)

Query: 15 EPKLSKNELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAA 55
          E K  K E K++ +A +KV E++ K  E+++  LSQ TAA+
Sbjct: 14 EDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAAS 54


>gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo
          sapiens]
          Length = 1029

 Score = 33.5 bits (75), Expect = 0.57
 Identities = 17/41 (41%), Positives = 27/41 (65%)

Query: 15 EPKLSKNELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAA 55
          E K  K E K++ +A +KV E++ K  E+++  LSQ TAA+
Sbjct: 50 EDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAAS 90


>gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo
          sapiens]
          Length = 1833

 Score = 33.5 bits (75), Expect = 0.57
 Identities = 17/41 (41%), Positives = 27/41 (65%)

Query: 15 EPKLSKNELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAA 55
          E K  K E K++ +A +KV E++ K  E+++  LSQ TAA+
Sbjct: 14 EDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAAS 54


>gi|54873624 eukaryotic translation initiation factor 2A [Homo
           sapiens]
          Length = 585

 Score = 33.1 bits (74), Expect = 0.75
 Identities = 30/81 (37%), Positives = 40/81 (49%), Gaps = 9/81 (11%)

Query: 13  GSEPKLSKNELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEESVD 72
           G++  LSK  LK + K E   A+K AKQ+  S+K    A   A   T  N V  +  S D
Sbjct: 475 GNDKPLSKTALKNQRKHE---AKKAAKQEARSDKSPDLAPTPAPQSTPRNTVS-QSISGD 530

Query: 73  PNQYYKIRS-----QAIHQLK 88
           P    KI++     +AI QLK
Sbjct: 531 PEIDKKIKNLKKKLKAIEQLK 551


>gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo
           sapiens]
          Length = 1157

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 27/75 (36%), Positives = 32/75 (42%), Gaps = 11/75 (14%)

Query: 2   AAVQAAEVKVDGSEPKLSKNELKRRLKAEKKVAEKEAKQKE-----------LSEKQLSQ 50
           A V   + K     P LSK E K   K EKKV +K  +QKE           LSE Q S+
Sbjct: 48  ALVLPGKKKKKTKAPPLSKKEKKPLTKKEKKVLQKILEQKEKKSQRAEMLQKLSEVQASE 107

Query: 51  ATAAATNHTTDNGVG 65
           A       T+  G G
Sbjct: 108 AEMRLFYTTSKLGTG 122


>gi|153791707 sorting nexin family member 30 [Homo sapiens]
          Length = 437

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 11/99 (11%)

Query: 288 NELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGID-----LTHNPEFTTCEFYM 342
           ++L+ +    + P L  K +V G +DR  E   + R + +D     +T +P  +  E + 
Sbjct: 141 SKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFN 200

Query: 343 AYADYHDLMEITEKMVSGM------VKHITGSYKVTYHP 375
            +    DL    ++ ++ +      VKH+TG YK+   P
Sbjct: 201 IFLTAKDLNAYKKQGIALLTRMGESVKHVTGGYKLRTRP 239


>gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo
           sapiens]
          Length = 732

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 6/109 (5%)

Query: 30  EKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEESV----DPNQYYKIRSQAIH 85
           +K+V++ EA++KE  E++  +    + +      VG +EE      D  +  KI+ + I 
Sbjct: 227 DKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYID 286

Query: 86  QLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPG--DHLTDITLKVAGRI 132
           Q ++N   P   +   DI+  ++ + Y  L     DHL      V G++
Sbjct: 287 QEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQL 335


>gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo
           sapiens]
          Length = 854

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 6/109 (5%)

Query: 30  EKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEESV----DPNQYYKIRSQAIH 85
           +K+V++ EA++KE  E++  +    + +      VG +EE      D  +  KI+ + I 
Sbjct: 349 DKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYID 408

Query: 86  QLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPG--DHLTDITLKVAGRI 132
           Q ++N   P   +   DI+  ++ + Y  L     DHL      V G++
Sbjct: 409 QEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQL 457


>gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]
          Length = 641

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 24/96 (25%), Positives = 50/96 (52%), Gaps = 5/96 (5%)

Query: 8   EVKVDGSEPKLSKNELKRR-LKAEKKVAEKEAKQKELSEKQLSQATA-AATNHTTDNGVG 65
           ++ +   + +LSK E++R  L AEK  AE E ++++++ K   ++ A    +  +D G+ 
Sbjct: 502 KITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAAKNALESYAFNMKSVVSDEGLK 561

Query: 66  PEEESVDPNQYYKIRSQAIHQLKVN---GEDPYPHK 98
            +    D N+     ++ +  L+VN    +D + HK
Sbjct: 562 GKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHK 597


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 15/60 (25%), Positives = 32/60 (53%)

Query: 10   KVDGSEPKLSKNELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEE 69
            + +  EP++ + E K R+  E++ +E+E ++ E  E +  +  AA T    D+    E++
Sbjct: 1262 ETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDD 1321


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 15/60 (25%), Positives = 32/60 (53%)

Query: 10   KVDGSEPKLSKNELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEE 69
            + +  EP++ + E K R+  E++ +E+E ++ E  E +  +  AA T    D+    E++
Sbjct: 1262 ETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDD 1321


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 15/60 (25%), Positives = 32/60 (53%)

Query: 10   KVDGSEPKLSKNELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEE 69
            + +  EP++ + E K R+  E++ +E+E ++ E  E +  +  AA T    D+    E++
Sbjct: 1262 ETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDD 1321


>gi|116642889 cyclic nucleotide gated channel beta 3 [Homo sapiens]
          Length = 809

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 9/60 (15%)

Query: 22  ELKRRLKAEKKV---------AEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEESVD 72
           +LKR   A+KK           E E KQKE  +KQ         N   D G  PEE+ +D
Sbjct: 693 KLKREQAAQKKENSEGGEEEGKENEDKQKENEDKQKENEDKGKENEDKDKGREPEEKPLD 752


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 22/47 (46%), Positives = 25/47 (53%), Gaps = 4/47 (8%)

Query: 8   EVKVDGSEPKLSKNELKRRLK--AEKKVA--EKEAKQKELSEKQLSQ 50
           EVK  G   KL+K   + R K  A KK    EKE K K L EKQL +
Sbjct: 131 EVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQE 177


>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
          Length = 4471

 Score = 31.2 bits (69), Expect = 2.8
 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 3/67 (4%)

Query: 347 YHDLMEITEKMVSGMVKH--ITGSYKVTYHPDGPE-GQAYDVDFTPPFRRINMVEELEKA 403
           Y   ME+TE+++  ++K   +T S   T  P   E G  + ++F+P  R I    +  + 
Sbjct: 623 YEQWMEVTEQVLPALMKKSLLTKSSIATEEPSTLERGAVFAINFSPALREIINETKYLEQ 682

Query: 404 LGMKLPE 410
           LG  +PE
Sbjct: 683 LGFTVPE 689


>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
           sapiens]
          Length = 2997

 Score = 31.2 bits (69), Expect = 2.8
 Identities = 21/93 (22%), Positives = 47/93 (50%), Gaps = 6/93 (6%)

Query: 12  DGSEPKLSKNELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEESV 71
           +  +P + K    R++K ++   + E K   +S+++   A AA  +  ++     ++ESV
Sbjct: 739 EDEDPGVQKRRSSRQVKRKRYTEDLEFK---ISDEEADDADAAGRDSPSNTSQSEQQESV 795

Query: 72  D---PNQYYKIRSQAIHQLKVNGEDPYPHKFHV 101
           D   P     + S+++ + K +GE+    +F+V
Sbjct: 796 DAEGPVVEKIMSSRSVKKQKESGEEVEIEEFYV 828


>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
           sapiens]
          Length = 956

 Score = 31.2 bits (69), Expect = 2.8
 Identities = 17/39 (43%), Positives = 27/39 (69%), Gaps = 1/39 (2%)

Query: 13  GSEPKL-SKNELKRRLKAEKKVAEKEAKQKELSEKQLSQ 50
           G + KL ++ E K +LK E K A++EAK+K+  EK+L +
Sbjct: 345 GKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKE 383


>gi|47419936 SFRS protein kinase 1 [Homo sapiens]
          Length = 655

 Score = 30.8 bits (68), Expect = 3.7
 Identities = 18/78 (23%), Positives = 35/78 (44%), Gaps = 1/78 (1%)

Query: 17  KLSKNELKRRLKAEKKVAE-KEAKQKELSEKQLSQATAAATNHTTDNGVGPEEESVDPNQ 75
           K+SKN+ K+  K +K+ AE  E + +E+ E +          +  +    P E  +  N 
Sbjct: 262 KMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQKRPNKQEESESPVERPLKENP 321

Query: 76  YYKIRSQAIHQLKVNGED 93
             K+  + + +    G+D
Sbjct: 322 PNKMTQEKLEESSTIGQD 339


>gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens]
          Length = 1012

 Score = 30.8 bits (68), Expect = 3.7
 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 2/39 (5%)

Query: 552 DRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLES 590
           D+    LTDS N   +LLFP+MKP  + E     D +++
Sbjct: 194 DKYTTLLTDSEN--RLLLFPSMKPNKRVEVAQLNDVMDT 230


>gi|51093834 hypothetical protein LOC126859 isoform 2 [Homo sapiens]
          Length = 938

 Score = 30.8 bits (68), Expect = 3.7
 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 2/39 (5%)

Query: 552 DRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLES 590
           D+    LTDS N   +LLFP+MKP  + E     D +++
Sbjct: 194 DKYTTLLTDSEN--RLLLFPSMKPNKRVEVAQLNDVMDT 230


>gi|142976783 PDZ domain containing RING finger 4 [Homo sapiens]
          Length = 778

 Score = 30.8 bits (68), Expect = 3.7
 Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 12/80 (15%)

Query: 4   VQAAEVKVDGSEPKLSKNELKRRLKAEKKVAE------------KEAKQKELSEKQLSQA 51
           V   E+++D    +  +NE    L  E    E            ++ K++E  E     A
Sbjct: 225 VARPEIQLDEGWLEDERNEFLEELNLEMLEEEHNEAMQPTANEVEQPKKQEEEEGTTDTA 284

Query: 52  TAAATNHTTDNGVGPEEESV 71
           T+++ NH  D+GVG  +ES+
Sbjct: 285 TSSSNNHEKDSGVGRTDESL 304


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 30.8 bits (68), Expect = 3.7
 Identities = 18/47 (38%), Positives = 28/47 (59%), Gaps = 2/47 (4%)

Query: 1   MAAVQAAEVKVDGSEPKLSKNELKRRLKAEKKVAEKEAKQKELSEKQ 47
           +A  QA +VK   ++ K  K E K  +K E K  EKE  +KE+++K+
Sbjct: 620 VAEKQATDVKPKAAKEKTVKKETK--VKPEDKKEEKEKPKKEVAKKE 664


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,982,698
Number of Sequences: 37866
Number of extensions: 1046114
Number of successful extensions: 4224
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 4130
Number of HSP's gapped (non-prelim): 103
length of query: 597
length of database: 18,247,518
effective HSP length: 108
effective length of query: 489
effective length of database: 14,157,990
effective search space: 6923257110
effective search space used: 6923257110
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.