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Search of human proteins with 5031715
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5031715 regulator of G-protein signalling 19 interacting
protein 1 isoform 1 [Homo sapiens]
(333 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42544140 regulator of G-protein signalling 19 interacting pro... 672 0.0
gi|42544144 regulator of G-protein signalling 19 interacting pro... 672 0.0
gi|5031715 regulator of G-protein signalling 19 interacting prot... 672 0.0
gi|42544142 regulator of G-protein signalling 19 interacting pro... 472 e-133
gi|42544146 regulator of G-protein signalling 19 interacting pro... 472 e-133
gi|42544149 regulator of G-protein signalling 19 interacting pro... 472 e-133
gi|18959204 GIPC PDZ domain containing family, member 3 [Homo sa... 390 e-109
gi|41393579 PDZ domain protein GIPC2 [Homo sapiens] 385 e-107
gi|87196343 PDZ domain containing 2 [Homo sapiens] 51 2e-06
gi|21536464 palmitoylated membrane protein 3 [Homo sapiens] 42 0.001
gi|148746189 multiple PDZ domain protein [Homo sapiens] 41 0.001
gi|27436957 membrane associated guanylate kinase, WW and PDZ dom... 41 0.002
gi|187607085 ligand of numb-protein X 1 isoform a [Homo sapiens] 41 0.002
gi|187607071 ligand of numb-protein X 1 isoform b [Homo sapiens] 41 0.002
gi|66346708 membrane associated guanylate kinase, WW and PDZ dom... 40 0.003
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom... 40 0.003
gi|74272282 membrane associated guanylate kinase, WW and PDZ dom... 40 0.003
gi|218505835 membrane-associated guanylate kinase-related 3 iso... 40 0.003
gi|155969695 membrane-associated guanylate kinase-related 3 iso... 40 0.003
gi|223890252 glutamate receptor interacting protein 1 [Homo sapi... 40 0.004
gi|186972120 calcium/calmodulin-dependent serine protein kinase ... 40 0.004
gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2) int... 39 0.006
gi|122937249 glutamate receptor interacting protein 2 [Homo sapi... 39 0.006
gi|111154074 palmitoylated membrane protein 7 [Homo sapiens] 39 0.008
gi|40807447 papillary renal cell carcinoma translocation-associa... 38 0.011
gi|93204861 protein phosphatase 1, regulatory (inhibitor) subuni... 38 0.011
gi|40807450 papillary renal cell carcinoma translocation-associa... 38 0.011
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 38 0.014
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 38 0.014
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ... 38 0.014
>gi|42544140 regulator of G-protein signalling 19 interacting
protein 1 isoform 1 [Homo sapiens]
Length = 333
Score = 672 bits (1734), Expect = 0.0
Identities = 333/333 (100%), Positives = 333/333 (100%)
Query: 1 MPLGLGRRKKAPPLVENEEAEPGRGGLGVGEPGPLGGGGSGGPQMGLPPPPPALRPRLVF 60
MPLGLGRRKKAPPLVENEEAEPGRGGLGVGEPGPLGGGGSGGPQMGLPPPPPALRPRLVF
Sbjct: 1 MPLGLGRRKKAPPLVENEEAEPGRGGLGVGEPGPLGGGGSGGPQMGLPPPPPALRPRLVF 60
Query: 61 HTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPTAEVMFCTLNTHKVDMDKLLGGQIGLE 120
HTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPTAEVMFCTLNTHKVDMDKLLGGQIGLE
Sbjct: 61 HTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPTAEVMFCTLNTHKVDMDKLLGGQIGLE 120
Query: 121 DFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEA 180
DFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEA
Sbjct: 121 DFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEA 180
Query: 181 INGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGR 240
INGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGR
Sbjct: 181 INGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGR 240
Query: 241 GTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDEL 300
GTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDEL
Sbjct: 241 GTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDEL 300
Query: 301 AEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 333
AEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY
Sbjct: 301 AEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 333
>gi|42544144 regulator of G-protein signalling 19 interacting
protein 1 isoform 1 [Homo sapiens]
Length = 333
Score = 672 bits (1734), Expect = 0.0
Identities = 333/333 (100%), Positives = 333/333 (100%)
Query: 1 MPLGLGRRKKAPPLVENEEAEPGRGGLGVGEPGPLGGGGSGGPQMGLPPPPPALRPRLVF 60
MPLGLGRRKKAPPLVENEEAEPGRGGLGVGEPGPLGGGGSGGPQMGLPPPPPALRPRLVF
Sbjct: 1 MPLGLGRRKKAPPLVENEEAEPGRGGLGVGEPGPLGGGGSGGPQMGLPPPPPALRPRLVF 60
Query: 61 HTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPTAEVMFCTLNTHKVDMDKLLGGQIGLE 120
HTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPTAEVMFCTLNTHKVDMDKLLGGQIGLE
Sbjct: 61 HTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPTAEVMFCTLNTHKVDMDKLLGGQIGLE 120
Query: 121 DFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEA 180
DFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEA
Sbjct: 121 DFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEA 180
Query: 181 INGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGR 240
INGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGR
Sbjct: 181 INGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGR 240
Query: 241 GTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDEL 300
GTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDEL
Sbjct: 241 GTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDEL 300
Query: 301 AEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 333
AEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY
Sbjct: 301 AEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 333
>gi|5031715 regulator of G-protein signalling 19 interacting protein
1 isoform 1 [Homo sapiens]
Length = 333
Score = 672 bits (1734), Expect = 0.0
Identities = 333/333 (100%), Positives = 333/333 (100%)
Query: 1 MPLGLGRRKKAPPLVENEEAEPGRGGLGVGEPGPLGGGGSGGPQMGLPPPPPALRPRLVF 60
MPLGLGRRKKAPPLVENEEAEPGRGGLGVGEPGPLGGGGSGGPQMGLPPPPPALRPRLVF
Sbjct: 1 MPLGLGRRKKAPPLVENEEAEPGRGGLGVGEPGPLGGGGSGGPQMGLPPPPPALRPRLVF 60
Query: 61 HTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPTAEVMFCTLNTHKVDMDKLLGGQIGLE 120
HTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPTAEVMFCTLNTHKVDMDKLLGGQIGLE
Sbjct: 61 HTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPTAEVMFCTLNTHKVDMDKLLGGQIGLE 120
Query: 121 DFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEA 180
DFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEA
Sbjct: 121 DFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEA 180
Query: 181 INGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGR 240
INGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGR
Sbjct: 181 INGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGR 240
Query: 241 GTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDEL 300
GTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDEL
Sbjct: 241 GTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDEL 300
Query: 301 AEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 333
AEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY
Sbjct: 301 AEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 333
>gi|42544142 regulator of G-protein signalling 19 interacting
protein 1 isoform 2 [Homo sapiens]
Length = 236
Score = 472 bits (1214), Expect = e-133
Identities = 236/236 (100%), Positives = 236/236 (100%)
Query: 98 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 157
MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI
Sbjct: 1 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 60
Query: 158 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 217
KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA
Sbjct: 61 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 120
Query: 218 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 277
FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG
Sbjct: 121 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 180
Query: 278 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 333
IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY
Sbjct: 181 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 236
>gi|42544146 regulator of G-protein signalling 19 interacting
protein 1 isoform 2 [Homo sapiens]
Length = 236
Score = 472 bits (1214), Expect = e-133
Identities = 236/236 (100%), Positives = 236/236 (100%)
Query: 98 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 157
MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI
Sbjct: 1 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 60
Query: 158 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 217
KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA
Sbjct: 61 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 120
Query: 218 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 277
FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG
Sbjct: 121 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 180
Query: 278 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 333
IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY
Sbjct: 181 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 236
>gi|42544149 regulator of G-protein signalling 19 interacting
protein 1 isoform 2 [Homo sapiens]
Length = 236
Score = 472 bits (1214), Expect = e-133
Identities = 236/236 (100%), Positives = 236/236 (100%)
Query: 98 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 157
MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI
Sbjct: 1 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 60
Query: 158 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 217
KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA
Sbjct: 61 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 120
Query: 218 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 277
FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG
Sbjct: 121 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 180
Query: 278 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 333
IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY
Sbjct: 181 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 236
>gi|18959204 GIPC PDZ domain containing family, member 3 [Homo
sapiens]
Length = 312
Score = 390 bits (1002), Expect = e-109
Identities = 193/287 (67%), Positives = 228/287 (79%)
Query: 43 PQMGLPPPPPALRPRLVFHTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPTAEVMFCTL 102
P PP P RPRLVF TQLAHGSPTG+IEGFTNV+ELY KIAEAF + E++FCTL
Sbjct: 22 PAPSEPPAAPRARPRLVFRTQLAHGSPTGKIEGFTNVRELYAKIAEAFGIAPTEILFCTL 81
Query: 103 NTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKE 162
N+HKVDM KLLGGQIGLEDFIFAHV+G+ KEVEV K+EDALGLTITDNGAGYAFIKRIKE
Sbjct: 82 NSHKVDMQKLLGGQIGLEDFIFAHVRGETKEVEVTKTEDALGLTITDNGAGYAFIKRIKE 141
Query: 163 GSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMIS 222
GS+I+ I + VGD IEAIN S++GCRHYEVA++L+ELP+ + FTL+L +P++AFDMI
Sbjct: 142 GSIINRIEAVCVGDSIEAINDHSIVGCRHYEVAKMLRELPKSQPFTLRLVQPKRAFDMIG 201
Query: 223 QRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTE 282
QRS + ++ +GR TLRLRS G ATVE+ PS FEE+A KVDDLLESYMGIRD E
Sbjct: 202 QRSRSSKCPVEAKVTSGRETLRLRSGGAATVEEAPSEFEEEASRKVDDLLESYMGIRDPE 261
Query: 283 LAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAK 329
LA+TMVE K + E A LD LG+FAFPDEFV +VW AIG+A+
Sbjct: 262 LASTMVETSKKTASAQEFARCLDSVLGEFAFPDEFVVEVWAAIGEAR 308
>gi|41393579 PDZ domain protein GIPC2 [Homo sapiens]
Length = 315
Score = 385 bits (988), Expect = e-107
Identities = 202/329 (61%), Positives = 247/329 (75%), Gaps = 18/329 (5%)
Query: 1 MPLGLGRRKKAPPLVENEEAEPGRGGLGVGEPGPLGGGGSGGPQMGLPPPPPALRPRLVF 60
MPL L +KKA +++E GL GEP GGG + A RLVF
Sbjct: 1 MPLKLRGKKKA----KSKET----AGLVEGEPTGAGGGSLSASR--------APARRLVF 44
Query: 61 HTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPTAEVMFCTLNTHKVDMDKLLGGQIGLE 120
H QLAHGS TGR+EGF++++ELY +IA AF + +E+++CTLNT K+DM++LLGGQ+GLE
Sbjct: 45 HAQLAHGSATGRVEGFSSIQELYAQIAGAFEISPSEILYCTLNTPKIDMERLLGGQLGLE 104
Query: 121 DFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEA 180
DFIFAHVKG KEV V+KSED+LGLTITDNG GYAFIKRIK+G VID + I VGD IE+
Sbjct: 105 DFIFAHVKGIEKEVNVYKSEDSLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGDHIES 164
Query: 181 INGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGR 240
ING++++G RHY+VA+ LKEL + FT+KL EP+KAF+ I RS G+ SG ++G GR
Sbjct: 165 INGENIVGWRHYDVAKKLKELKKEELFTMKLIEPKKAFE-IELRSKAGK-SSGEKIGCGR 222
Query: 241 GTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDEL 300
TLRLRS+GPATVE++PS + KAIEK+DD+LE YMGIRD +LA TM E GKDK NPDE
Sbjct: 223 ATLRLRSKGPATVEEMPSETKAKAIEKIDDVLELYMGIRDIDLATTMFEAGKDKVNPDEF 282
Query: 301 AEALDERLGDFAFPDEFVFDVWGAIGDAK 329
A ALDE LGDFAFPDEFVFDVWG IGDAK
Sbjct: 283 AVALDETLGDFAFPDEFVFDVWGVIGDAK 311
>gi|87196343 PDZ domain containing 2 [Homo sapiens]
Length = 2839
Score = 50.8 bits (120), Expect = 2e-06
Identities = 27/76 (35%), Positives = 41/76 (53%), Gaps = 5/76 (6%)
Query: 134 VEVFKSEDALGLTITDN-----GAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLG 188
VEV K+ LGL++ G G IKR+ +G + +I GD I AING+ L+G
Sbjct: 2751 VEVLKTSAGLGLSLDGGKSSVTGDGPLVIKRVYKGGAAEQAGIIEAGDEILAINGKPLVG 2810
Query: 189 CRHYEVARLLKELPRG 204
H++ ++K +P G
Sbjct: 2811 LMHFDAWNIMKSVPEG 2826
Score = 36.6 bits (83), Expect = 0.032
Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 7/77 (9%)
Query: 129 GQRKEVEVFKSEDALGLTITDNGAGYA------FIKRIKEGSVIDHIHLISVGDMIEAIN 182
G+ ++E+ K D LG+ ++ G G + ++KEG +S+GD + IN
Sbjct: 330 GRIWKMELLKESDGLGIQVS-GGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDELLVIN 388
Query: 183 GQSLLGCRHYEVARLLK 199
G L+G H E +L+
Sbjct: 389 GHLLVGLSHEEAVAILR 405
>gi|21536464 palmitoylated membrane protein 3 [Homo sapiens]
Length = 585
Score = 41.6 bits (96), Expect = 0.001
Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 3/93 (3%)
Query: 132 KEVEVFKSEDALGLTIT-DNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCR 190
K V + K+++ LG TI D +G + RI G D L+ VGD + +NG ++L R
Sbjct: 136 KIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKR 195
Query: 191 HYEVARLLKELPRGRTFTLKLTEPRKAFDMISQ 223
E++++L + + TLK+ + D + +
Sbjct: 196 PDEISQILAQ--SQGSITLKIIPATQEEDRLKE 226
>gi|148746189 multiple PDZ domain protein [Homo sapiens]
Length = 2041
Score = 41.2 bits (95), Expect = 0.001
Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 19/97 (19%)
Query: 128 KGQRKE---VEVFKSEDALGLTITDNGAGYA----------FIKRIKEGSVIDHIHLISV 174
KG+ E VE+ K+ LG+TI AGY F+K I + S ++H I +
Sbjct: 369 KGEESETFDVELTKNVQGLGITI----AGYIGDKKLEPSGIFVKSITKSSAVEHDGRIQI 424
Query: 175 GDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKL 211
GD I A++G +L G + + +L+ G+T L L
Sbjct: 425 GDQIIAVDGTNLQGFTNQQAVEVLRH--TGQTVLLTL 459
Score = 41.2 bits (95), Expect = 0.001
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 134 VEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYE 193
V F LG+++ + G+ FI+ + + H + GD + +NG +LLG H +
Sbjct: 556 VSKFSENSGLGISL-EATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGITLLGENHQD 614
Query: 194 VARLLKELP 202
V +LKELP
Sbjct: 615 VVNILKELP 623
Score = 34.3 bits (77), Expect = 0.16
Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
Query: 132 KEVEVFKSEDALGLTITDNGAGYAFIKR-IKEGSVIDHIHLISVGDMIEAINGQSLLGCR 190
+ + + K +LG+T++ N G I R I G I I++GD I +IN +S +
Sbjct: 1007 RTINIAKGNSSLGMTVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVT 1066
Query: 191 HYEVARLLK 199
+ + +L+
Sbjct: 1067 NAQARAMLR 1075
Score = 33.5 bits (75), Expect = 0.27
Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Query: 130 QRKEVEVFKSEDALGLTI-----TDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQ 184
Q K + + + D LG +I + +G ++K + + GD I A+NGQ
Sbjct: 1955 QCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAVNGQ 2014
Query: 185 SLLGCRHYEVARLLK 199
SL G H E +LK
Sbjct: 2015 SLEGVTHEEAVAILK 2029
Score = 32.0 bits (71), Expect = 0.79
Identities = 23/86 (26%), Positives = 35/86 (40%), Gaps = 3/86 (3%)
Query: 127 VKGQRKEVEVFKSEDALGLTI---TDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAING 183
+ G +E+ K LGL+I +D G I + E + GD I +NG
Sbjct: 1623 IPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNG 1682
Query: 184 QSLLGCRHYEVARLLKELPRGRTFTL 209
L H E +L++ P+ TL
Sbjct: 1683 IDLRKATHDEAINVLRQTPQRVRLTL 1708
Score = 30.4 bits (67), Expect = 2.3
Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 9/66 (13%)
Query: 130 QRKEVEVFK---------SEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEA 180
Q + VEVF+ +GL + G F++ I+EGSV + D I A
Sbjct: 131 QGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDGRLKETDQILA 190
Query: 181 INGQSL 186
INGQ+L
Sbjct: 191 INGQAL 196
Score = 28.9 bits (63), Expect = 6.7
Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 3/64 (4%)
Query: 138 KSEDALGLTITD--NGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVA 195
K LGL+I N G F+ I +G + D + GD I +NG+ + VA
Sbjct: 1731 KPGKGLGLSIVGKRNDTG-VFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVA 1789
Query: 196 RLLK 199
LLK
Sbjct: 1790 ALLK 1793
Score = 28.5 bits (62), Expect = 8.7
Identities = 29/120 (24%), Positives = 55/120 (45%), Gaps = 6/120 (5%)
Query: 132 KEVEVFKSEDALGLTITDNGA-GYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCR 190
+ +E+ K + LG+ I++ IK + E V + VGD I A++ + ++G
Sbjct: 1482 QHLELPKDQGGLGIAISEEDTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVG-- 1539
Query: 191 HYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGP 250
Y + + + L + T+KLT + D + SA G SG + + + + +S P
Sbjct: 1540 -YPIEKFISLLKTAK-MTVKLTIHAENPDSQAVPSAAG-AASGEKKNSSQSLMVPQSGSP 1596
>gi|27436957 membrane associated guanylate kinase, WW and PDZ domain
containing 2 [Homo sapiens]
Length = 1455
Score = 40.8 bits (94), Expect = 0.002
Identities = 21/55 (38%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
Query: 157 IKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKL 211
I RI +GS D + VGD I A+NGQS++ H ++ +L+K+ G + TL++
Sbjct: 954 IGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKD--AGLSVTLRI 1006
Score = 35.4 bits (80), Expect = 0.072
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 4/74 (5%)
Query: 136 VFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVA 195
+ K G TI D+ G +R+K+ I + GD+I IN Q++ H EV
Sbjct: 608 IVKGAQGFGFTIADSPTG----QRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVV 663
Query: 196 RLLKELPRGRTFTL 209
+LK+ P G +L
Sbjct: 664 DILKDCPIGSETSL 677
Score = 30.0 bits (66), Expect = 3.0
Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 2/89 (2%)
Query: 125 AHVKGQRKEVEVFKSEDALGLTIT--DNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAIN 182
+ +KG + KS G TI D + +K + + GD+I IN
Sbjct: 418 SQLKGTFLSTTLKKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYIN 477
Query: 183 GQSLLGCRHYEVARLLKELPRGRTFTLKL 211
+LG H +V +L + +P G++ L L
Sbjct: 478 EVCVLGHTHADVVKLFQSVPIGQSVNLVL 506
>gi|187607085 ligand of numb-protein X 1 isoform a [Homo sapiens]
Length = 728
Score = 40.8 bits (94), Expect = 0.002
Identities = 26/60 (43%), Positives = 34/60 (56%)
Query: 150 NGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTL 209
NG FIK I EG+ + I GD++ A+NG+S G H +ARLLKEL T T+
Sbjct: 661 NGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKELKGRITLTI 720
>gi|187607071 ligand of numb-protein X 1 isoform b [Homo sapiens]
Length = 632
Score = 40.8 bits (94), Expect = 0.002
Identities = 26/60 (43%), Positives = 34/60 (56%)
Query: 150 NGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTL 209
NG FIK I EG+ + I GD++ A+NG+S G H +ARLLKEL T T+
Sbjct: 565 NGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKELKGRITLTI 624
>gi|66346708 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform b [Homo sapiens]
Length = 1256
Score = 40.0 bits (92), Expect = 0.003
Identities = 23/55 (41%), Positives = 31/55 (56%), Gaps = 2/55 (3%)
Query: 157 IKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKL 211
I RI EGS D + VGD I A+NG S+ H ++ L+KE G T TL++
Sbjct: 1038 IGRIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKE--AGNTVTLRI 1090
Score = 35.0 bits (79), Expect = 0.093
Identities = 33/164 (20%), Positives = 64/164 (39%), Gaps = 23/164 (14%)
Query: 47 LPPPPPALRPRLVFHTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPTAEVMFCTLNTHK 106
L P + + + + +H S TG++ G + + P++ + ++H
Sbjct: 576 LDKEPIIVNGQETYDSPASHSSKTGKVNGMKDAR------------PSSPADVASNSSHG 623
Query: 107 VDMDKL-LGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSV 165
D + L I + + V + K G TI D+ G +R+K+
Sbjct: 624 YPNDTVSLASSIATQPELIT--------VHIVKGPMGFGFTIADSPGGGG--QRVKQIVD 673
Query: 166 IDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTL 209
+ GD+I +N +++ H +V +L E P+G TL
Sbjct: 674 SPRCRGLKEGDLIVEVNKKNVQALTHNQVVDMLVECPKGSEVTL 717
Score = 31.2 bits (69), Expect = 1.3
Identities = 21/89 (23%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
Query: 125 AHVKGQRKEVEVFKSEDALGLTIT--DNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAIN 182
+ +KG+ ++ KS G T+ D + IK + + GD+I ++N
Sbjct: 464 SELKGKFIHTKLRKSSRGFGFTVVGGDEPDEFLQIKSLVLDGPAALDGKMETGDVIVSVN 523
Query: 183 GQSLLGCRHYEVARLLKELPRGRTFTLKL 211
+LG H +V ++ + +P G + L+L
Sbjct: 524 DTCVLGHTHAQVVKIFQSIPIGASVDLEL 552
>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform c [Homo sapiens]
Length = 1462
Score = 40.0 bits (92), Expect = 0.003
Identities = 23/55 (41%), Positives = 31/55 (56%), Gaps = 2/55 (3%)
Query: 157 IKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKL 211
I RI EGS D + VGD I A+NG S+ H ++ L+KE G T TL++
Sbjct: 1009 IGRIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKE--AGNTVTLRI 1061
Score = 35.0 bits (79), Expect = 0.093
Identities = 33/164 (20%), Positives = 64/164 (39%), Gaps = 23/164 (14%)
Query: 47 LPPPPPALRPRLVFHTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPTAEVMFCTLNTHK 106
L P + + + + +H S TG++ G + + P++ + ++H
Sbjct: 576 LDKEPIIVNGQETYDSPASHSSKTGKVNGMKDAR------------PSSPADVASNSSHG 623
Query: 107 VDMDKL-LGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSV 165
D + L I + + V + K G TI D+ G +R+K+
Sbjct: 624 YPNDTVSLASSIATQPELIT--------VHIVKGPMGFGFTIADSPGGGG--QRVKQIVD 673
Query: 166 IDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTL 209
+ GD+I +N +++ H +V +L E P+G TL
Sbjct: 674 SPRCRGLKEGDLIVEVNKKNVQALTHNQVVDMLVECPKGSEVTL 717
Score = 31.2 bits (69), Expect = 1.3
Identities = 21/89 (23%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
Query: 125 AHVKGQRKEVEVFKSEDALGLTIT--DNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAIN 182
+ +KG+ ++ KS G T+ D + IK + + GD+I ++N
Sbjct: 464 SELKGKFIHTKLRKSSRGFGFTVVGGDEPDEFLQIKSLVLDGPAALDGKMETGDVIVSVN 523
Query: 183 GQSLLGCRHYEVARLLKELPRGRTFTLKL 211
+LG H +V ++ + +P G + L+L
Sbjct: 524 DTCVLGHTHAQVVKIFQSIPIGASVDLEL 552
>gi|74272282 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform a [Homo sapiens]
Length = 1287
Score = 40.0 bits (92), Expect = 0.003
Identities = 23/55 (41%), Positives = 31/55 (56%), Gaps = 2/55 (3%)
Query: 157 IKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKL 211
I RI EGS D + VGD I A+NG S+ H ++ L+KE G T TL++
Sbjct: 1037 IGRIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKE--AGNTVTLRI 1089
Score = 35.0 bits (79), Expect = 0.093
Identities = 33/164 (20%), Positives = 64/164 (39%), Gaps = 23/164 (14%)
Query: 47 LPPPPPALRPRLVFHTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPTAEVMFCTLNTHK 106
L P + + + + +H S TG++ G + + P++ + ++H
Sbjct: 576 LDKEPIIVNGQETYDSPASHSSKTGKVNGMKDAR------------PSSPADVASNSSHG 623
Query: 107 VDMDKL-LGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSV 165
D + L I + + V + K G TI D+ G +R+K+
Sbjct: 624 YPNDTVSLASSIATQPELIT--------VHIVKGPMGFGFTIADSPGGGG--QRVKQIVD 673
Query: 166 IDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTL 209
+ GD+I +N +++ H +V +L E P+G TL
Sbjct: 674 SPRCRGLKEGDLIVEVNKKNVQALTHNQVVDMLVECPKGSEVTL 717
Score = 31.2 bits (69), Expect = 1.3
Identities = 21/89 (23%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
Query: 125 AHVKGQRKEVEVFKSEDALGLTIT--DNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAIN 182
+ +KG+ ++ KS G T+ D + IK + + GD+I ++N
Sbjct: 464 SELKGKFIHTKLRKSSRGFGFTVVGGDEPDEFLQIKSLVLDGPAALDGKMETGDVIVSVN 523
Query: 183 GQSLLGCRHYEVARLLKELPRGRTFTLKL 211
+LG H +V ++ + +P G + L+L
Sbjct: 524 DTCVLGHTHAQVVKIFQSIPIGASVDLEL 552
>gi|218505835 membrane-associated guanylate kinase-related 3
isoform 1 [Homo sapiens]
Length = 1481
Score = 40.0 bits (92), Expect = 0.003
Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 12/101 (11%)
Query: 157 IKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRK 216
I R+ EGS D + VGD I A+NGQS++ H + +L+K+ G T TL
Sbjct: 882 IGRVIEGSPADRCGKLKVGDHISAVNGQSIVELSHDNIVQLIKD--AGVTVTL------- 932
Query: 217 AFDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLP 257
+I++ G P SG L+ R G + +P
Sbjct: 933 --TVIAEEEHHG-PPSGTNSARQSPALQHRPMGQSQANHIP 970
Score = 30.8 bits (68), Expect = 1.8
Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Query: 125 AHVKGQRKEVEVFKSEDALGLTIT--DNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAIN 182
+ +KG + KS G TI D + +K + + I+ GD+I IN
Sbjct: 402 SQLKGVLVRASLKKSTMGFGFTIIGGDRPDEFLQVKNVLKDGPAAQDGKIAPGDVIVDIN 461
Query: 183 GQSLLGCRHYEVARLLKELPRGRTFTLKL 211
G +LG H +V ++ + +P + L L
Sbjct: 462 GNCVLGHTHADVVQMFQLVPVNQYVNLTL 490
>gi|155969695 membrane-associated guanylate kinase-related 3
isoform 2 [Homo sapiens]
Length = 1125
Score = 40.0 bits (92), Expect = 0.003
Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 12/101 (11%)
Query: 157 IKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRK 216
I R+ EGS D + VGD I A+NGQS++ H + +L+K+ G T TL
Sbjct: 882 IGRVIEGSPADRCGKLKVGDHISAVNGQSIVELSHDNIVQLIKD--AGVTVTL------- 932
Query: 217 AFDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLP 257
+I++ G P SG L+ R G + +P
Sbjct: 933 --TVIAEEEHHG-PPSGTNSARQSPALQHRPMGQSQANHIP 970
Score = 30.8 bits (68), Expect = 1.8
Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Query: 125 AHVKGQRKEVEVFKSEDALGLTIT--DNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAIN 182
+ +KG + KS G TI D + +K + + I+ GD+I IN
Sbjct: 402 SQLKGVLVRASLKKSTMGFGFTIIGGDRPDEFLQVKNVLKDGPAAQDGKIAPGDVIVDIN 461
Query: 183 GQSLLGCRHYEVARLLKELPRGRTFTLKL 211
G +LG H +V ++ + +P + L L
Sbjct: 462 GNCVLGHTHADVVQMFQLVPVNQYVNLTL 490
>gi|223890252 glutamate receptor interacting protein 1 [Homo
sapiens]
Length = 1076
Score = 39.7 bits (91), Expect = 0.004
Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 3/71 (4%)
Query: 134 VEVFKSEDA-LGLTITD--NGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCR 190
VE+ K E LGLT++ + G + +++G + + VGD I+A+NG +L R
Sbjct: 54 VELMKKEGTTLGLTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKAVNGINLAKFR 113
Query: 191 HYEVARLLKEL 201
H E+ LLK +
Sbjct: 114 HDEIISLLKNV 124
Score = 33.9 bits (76), Expect = 0.21
Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
Query: 134 VEVFKSEDALGLTI--TDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRH 191
VE+ + LG+TI T+ I + +G + + I +GD I AIN SL G
Sbjct: 622 VELKRYGGPLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPL 681
Query: 192 YEVARLLKELPRGRTFTLKLTEPRKA 217
E LL+ G T TLK+ + A
Sbjct: 682 SEAIHLLQ--MAGETVTLKIKKQTDA 705
Score = 30.4 bits (67), Expect = 2.3
Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
Query: 134 VEVFKSEDA-LGLTITDN---GAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGC 189
VEV K+ A LG+ +T + I +IK S+ D + VGD I +I+G S+ C
Sbjct: 253 VEVAKTPGASLGVALTTSMCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTSMEYC 312
Query: 190 RHYEVARLL 198
E + L
Sbjct: 313 TLAEATQFL 321
Score = 28.5 bits (62), Expect = 8.7
Identities = 20/74 (27%), Positives = 31/74 (41%), Gaps = 6/74 (8%)
Query: 133 EVEVFKSEDALGLTITD------NGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSL 186
EV + K + G I N + I ++ G D I GD + +++G L
Sbjct: 152 EVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRL 211
Query: 187 LGCRHYEVARLLKE 200
LG H E +LK+
Sbjct: 212 LGTTHAEAMSILKQ 225
>gi|186972120 calcium/calmodulin-dependent serine protein kinase
isoform 1 [Homo sapiens]
Length = 921
Score = 39.7 bits (91), Expect = 0.004
Identities = 31/125 (24%), Positives = 55/125 (44%), Gaps = 10/125 (8%)
Query: 139 SEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLL 198
+++ +G+T+ N + + RI G +I + VGD I ING S+ ++ ++L
Sbjct: 497 TDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKML 556
Query: 199 KELPRGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPS 258
+E+ RG + T K+ + +R + P G S +V DLPS
Sbjct: 557 REM-RG-SITFKIVPSYRTQSSSCERDSPSTSRQSPANG--------HSSTNNSVSDLPS 606
Query: 259 AFEEK 263
+ K
Sbjct: 607 TTQPK 611
>gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2)
interacting protein [Homo sapiens]
Length = 1211
Score = 38.9 bits (89), Expect = 0.006
Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 3/71 (4%)
Query: 129 GQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLG 188
G R+ V V+K + G T+ G G +I+ + GS D+ L S GD I +NG +
Sbjct: 275 GARRTVRVYKGNKSFGFTL--RGHGPVWIESVLPGSPADNAALKS-GDRILFLNGLDMRN 331
Query: 189 CRHYEVARLLK 199
C H +V +L+
Sbjct: 332 CSHDKVVSMLQ 342
Score = 30.8 bits (68), Expect = 1.8
Identities = 36/150 (24%), Positives = 55/150 (36%), Gaps = 26/150 (17%)
Query: 151 GAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLK 210
G+G F+ + +GS H + GD I + G ++ G + RL + PR
Sbjct: 23 GSGPCFVLEVAKGSSA-HAGGLRPGDQILEVEGLAVGGLSRERLVRLARRCPR------- 74
Query: 211 LTEPRKAFDMISQRSAGGRPGSGPQ--------------LGTGRGTLRLRSR-GPATVED 255
+ ++ G PGSGP L GR LRL R P V
Sbjct: 75 ---VPPSLGVLPAPDGGPGPGSGPAAPTTVLRAPRCGRGLALGRELLRLAGRKRPDAVHR 131
Query: 256 LPSAFEEKAIEKVDDLLESYMGIRDTELAA 285
++ KVD++L ++ AA
Sbjct: 132 ERRRKAQEFSRKVDEILGDQPTAKEQVFAA 161
>gi|122937249 glutamate receptor interacting protein 2 [Homo
sapiens]
Length = 1141
Score = 38.9 bits (89), Expect = 0.006
Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 3/71 (4%)
Query: 134 VEVFKSEDA-LGLTITD--NGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCR 190
VE+ K E + LGLTI+ + G + ++ G + L+++GD I ++NG L R
Sbjct: 146 VELIKKEGSTLGLTISGGTDKDGKPRVSNLRPGGLAARSDLLNIGDYIRSVNGIHLTRLR 205
Query: 191 HYEVARLLKEL 201
H E+ LLK +
Sbjct: 206 HDEIITLLKNV 216
Score = 34.7 bits (78), Expect = 0.12
Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 4/72 (5%)
Query: 134 VEVFKSE-DALGLTITDNGA---GYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGC 189
VE+ K+ ALG+++T I RIK SV+D + GD I +I+G S+ C
Sbjct: 346 VEIVKTPGSALGISLTTTSLRNKSVITIDRIKPASVVDRSGALHPGDHILSIDGTSMEHC 405
Query: 190 RHYEVARLLKEL 201
E +LL +
Sbjct: 406 SLLEATKLLASI 417
Score = 32.3 bits (72), Expect = 0.61
Identities = 41/151 (27%), Positives = 59/151 (39%), Gaps = 29/151 (19%)
Query: 134 VEVFKSEDALGLTI--TDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRH 191
VE+ + LG+TI T+ I + + + + I VGD I AIN SL G
Sbjct: 755 VELKRYGGPLGITISGTEEPFDPIVISGLTKRGLAERTGAIHVGDRILAINNVSLKGRPL 814
Query: 192 YEVARLLKELPRGRTFTLKLTE-------PRKAFDMISQRSAGGRPGSGPQLGTGRGTLR 244
E LL+ G T TLK+ + PRK+ + A P + G
Sbjct: 815 SEAIHLLQ--VAGETVTLKIKKQLDRPLLPRKSGSLSETSDADEDPADALKGG------- 865
Query: 245 LRSRGPATVEDLPSAFEEKAIEKVDDLLESY 275
LP+A A+ VD +ES+
Sbjct: 866 -----------LPAARFSPAVPSVDSAVESW 885
>gi|111154074 palmitoylated membrane protein 7 [Homo sapiens]
Length = 576
Score = 38.5 bits (88), Expect = 0.008
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
Query: 132 KEVEVFKSEDALGLTIT-DNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCR 190
K + + K+ + LG TI D G + RI G D LI VGD + +NG + R
Sbjct: 138 KIIRLVKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIHVGDELREVNGIPVEDKR 197
Query: 191 HYEVARLLKELPRGRTFTL 209
E+ ++L + TF +
Sbjct: 198 PEEIIQILAQSQGAITFKI 216
>gi|40807447 papillary renal cell carcinoma translocation-associated
gene product isoform 1 [Homo sapiens]
Length = 491
Score = 38.1 bits (87), Expect = 0.011
Identities = 26/74 (35%), Positives = 32/74 (43%), Gaps = 8/74 (10%)
Query: 1 MPLGLGRRKKAPPLVENEEAEPGRGGLGVGEPGPLGGG-------GSGGPQMGLPPPPPA 53
+P GLG P + E A G G LG+G P P G G G GP +GLP P
Sbjct: 83 LPFGLGGFPPPPGVSPAEAAGVGEG-LGLGLPSPRGPGLNLPPPIGGAGPPLGLPKPKKR 141
Query: 54 LRPRLVFHTQLAHG 67
P + +L G
Sbjct: 142 KEPVKIAAPELHKG 155
>gi|93204861 protein phosphatase 1, regulatory (inhibitor) subunit
9A [Homo sapiens]
Length = 1098
Score = 38.1 bits (87), Expect = 0.011
Identities = 26/89 (29%), Positives = 38/89 (42%), Gaps = 8/89 (8%)
Query: 134 VEVFKSEDALGLTITDNGAGY--------AFIKRIKEGSVIDHIHLISVGDMIEAINGQS 185
VE+ K ED LG++I G G F+K + EG I V D I ++G S
Sbjct: 505 VELEKDEDGLGISIIGMGVGADAGLEKLGIFVKTVTEGGAAQRDGRIQVNDQIVEVDGIS 564
Query: 186 LLGCRHYEVARLLKELPRGRTFTLKLTEP 214
L+G A +L+ F + +P
Sbjct: 565 LVGVTQNFAATVLRNTKGNVRFVIGREKP 593
>gi|40807450 papillary renal cell carcinoma translocation-associated
gene product isoform 2 [Homo sapiens]
Length = 459
Score = 38.1 bits (87), Expect = 0.011
Identities = 26/74 (35%), Positives = 32/74 (43%), Gaps = 8/74 (10%)
Query: 1 MPLGLGRRKKAPPLVENEEAEPGRGGLGVGEPGPLGGG-------GSGGPQMGLPPPPPA 53
+P GLG P + E A G G LG+G P P G G G GP +GLP P
Sbjct: 83 LPFGLGGFPPPPGVSPAEAAGVGEG-LGLGLPSPRGPGLNLPPPIGGAGPPLGLPKPKKR 141
Query: 54 LRPRLVFHTQLAHG 67
P + +L G
Sbjct: 142 KEPVKIAAPELHKG 155
>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 37.7 bits (86), Expect = 0.014
Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 9/78 (11%)
Query: 1 MPLGLGRRKKAPPLVENEEAEPGRGGLGVGEPGPLGGGGSGGPQ---MGLPPPPPALRPR 57
MP G G R P + ++ P RG P P G GG GG + + LPPPPP
Sbjct: 264 MPPGRGGRPMPPSRRDYDDMSPRRGP----PPPPPGRGGRGGSRARNLPLPPPPPPRGGD 319
Query: 58 LVFHTQLAHGSPTGRIEG 75
L+ + + G P R +G
Sbjct: 320 LMAYDR--RGRPGDRYDG 335
>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
[Homo sapiens]
Length = 463
Score = 37.7 bits (86), Expect = 0.014
Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 9/78 (11%)
Query: 1 MPLGLGRRKKAPPLVENEEAEPGRGGLGVGEPGPLGGGGSGGPQ---MGLPPPPPALRPR 57
MP G G R P + ++ P RG P P G GG GG + + LPPPPP
Sbjct: 264 MPPGRGGRPMPPSRRDYDDMSPRRGP----PPPPPGRGGRGGSRARNLPLPPPPPPRGGD 319
Query: 58 LVFHTQLAHGSPTGRIEG 75
L+ + + G P R +G
Sbjct: 320 LMAYDR--RGRPGDRYDG 335
>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 37.7 bits (86), Expect = 0.014
Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 9/78 (11%)
Query: 1 MPLGLGRRKKAPPLVENEEAEPGRGGLGVGEPGPLGGGGSGGPQ---MGLPPPPPALRPR 57
MP G G R P + ++ P RG P P G GG GG + + LPPPPP
Sbjct: 264 MPPGRGGRPMPPSRRDYDDMSPRRGP----PPPPPGRGGRGGSRARNLPLPPPPPPRGGD 319
Query: 58 LVFHTQLAHGSPTGRIEG 75
L+ + + G P R +G
Sbjct: 320 LMAYDR--RGRPGDRYDG 335
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.141 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,873,139
Number of Sequences: 37866
Number of extensions: 867162
Number of successful extensions: 8968
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 144
Number of HSP's successfully gapped in prelim test: 235
Number of HSP's that attempted gapping in prelim test: 7152
Number of HSP's gapped (non-prelim): 1899
length of query: 333
length of database: 18,247,518
effective HSP length: 103
effective length of query: 230
effective length of database: 14,347,320
effective search space: 3299883600
effective search space used: 3299883600
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.