Guide to the Human Genome
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Search of human proteins with 48928019

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|48928019 Nedd4 binding protein 1 [Homo sapiens]
         (896 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|48928019 Nedd4 binding protein 1 [Homo sapiens]                   1794   0.0  
gi|54792090 hypothetical protein LOC23351 [Homo sapiens]              252   1e-66
gi|126723547 hypothetical protein LOC57523 [Homo sapiens]             204   4e-52
gi|148886668 zinc finger CCCH-type containing 12C [Homo sapiens]      176   1e-43
gi|156151383 zinc finger CCCH-type containing 12A [Homo sapiens]      173   6e-43
gi|148746187 zinc finger CCCH-type containing 12B [Homo sapiens]      172   2e-42
gi|148762945 zinc finger CCCH-type containing 12D [Homo sapiens]      162   2e-39
gi|65507253 hypothetical protein LOC55196 [Homo sapiens]               40   0.010
gi|54112394 calcium channel, voltage-dependent, alpha 2/delta su...    40   0.013
gi|54112392 calcium channel, voltage-dependent, alpha 2/delta su...    40   0.013
gi|239755810 PREDICTED: hypothetical protein [Homo sapiens]            39   0.017
gi|239750310 PREDICTED: hypothetical protein [Homo sapiens]            39   0.017
gi|239744621 PREDICTED: hypothetical protein [Homo sapiens]            39   0.017
gi|22095367 centrosomal protein 63 isoform a [Homo sapiens]            39   0.022
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    38   0.048
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]             37   0.082
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]             37   0.082
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    37   0.11 
gi|55770834 centromere protein F [Homo sapiens]                        36   0.14 
gi|17865632 mitochondrial tumor suppressor 1 isoform 5 [Homo sap...    36   0.18 
gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sap...    36   0.18 
gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo sap...    36   0.18 
gi|50348626 mitochondrial tumor suppressor 1 isoform 4 [Homo sap...    36   0.18 
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             36   0.18 
gi|31982906 cingulin-like 1 [Homo sapiens]                             35   0.24 
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]    35   0.31 
gi|4506105 prolactin precursor [Homo sapiens]                          35   0.41 
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    35   0.41 
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    35   0.41 
gi|19923597 Sin3A-associated protein, 130kDa isoform b [Homo sap...    35   0.41 

>gi|48928019 Nedd4 binding protein 1 [Homo sapiens]
          Length = 896

 Score = 1794 bits (4646), Expect = 0.0
 Identities = 896/896 (100%), Positives = 896/896 (100%)

Query: 1   MAARAVLDEFTAPAEKAELLEQSRGRIEGLFGVSLAVLGALGAEEPLPARIWLQLCGAQE 60
           MAARAVLDEFTAPAEKAELLEQSRGRIEGLFGVSLAVLGALGAEEPLPARIWLQLCGAQE
Sbjct: 1   MAARAVLDEFTAPAEKAELLEQSRGRIEGLFGVSLAVLGALGAEEPLPARIWLQLCGAQE 60

Query: 61  AVHSAKEYIKGICEPELEERECYPKDMHCIFVGAESLFLKSLIQDTCADLCILDIGLLGI 120
           AVHSAKEYIKGICEPELEERECYPKDMHCIFVGAESLFLKSLIQDTCADLCILDIGLLGI
Sbjct: 61  AVHSAKEYIKGICEPELEERECYPKDMHCIFVGAESLFLKSLIQDTCADLCILDIGLLGI 120

Query: 121 RGSAEAVVMARSHIQQFVKLFENKENLPSSQKESEVKREFKQFVEAHADNYTMDLLILPT 180
           RGSAEAVVMARSHIQQFVKLFENKENLPSSQKESEVKREFKQFVEAHADNYTMDLLILPT
Sbjct: 121 RGSAEAVVMARSHIQQFVKLFENKENLPSSQKESEVKREFKQFVEAHADNYTMDLLILPT 180

Query: 181 SLKKELLTLTQGEENLFETGDDEVIEMRDSQQTEFTQNAATGLNISRDETVLQEEARNKA 240
           SLKKELLTLTQGEENLFETGDDEVIEMRDSQQTEFTQNAATGLNISRDETVLQEEARNKA
Sbjct: 181 SLKKELLTLTQGEENLFETGDDEVIEMRDSQQTEFTQNAATGLNISRDETVLQEEARNKA 240

Query: 241 GTPVSELTKQMDTVLSSSPDVLFDPINGLTPDEEALSNERICQKRRFSDSEERHTKKQFS 300
           GTPVSELTKQMDTVLSSSPDVLFDPINGLTPDEEALSNERICQKRRFSDSEERHTKKQFS
Sbjct: 241 GTPVSELTKQMDTVLSSSPDVLFDPINGLTPDEEALSNERICQKRRFSDSEERHTKKQFS 300

Query: 301 LENVQEGEILHDAKTLAGNVIADLSDSSADSENLSPDIKETTEEMEYNILVNFFKTMGYS 360
           LENVQEGEILHDAKTLAGNVIADLSDSSADSENLSPDIKETTEEMEYNILVNFFKTMGYS
Sbjct: 301 LENVQEGEILHDAKTLAGNVIADLSDSSADSENLSPDIKETTEEMEYNILVNFFKTMGYS 360

Query: 361 QEIVEKVIKVYGPSTEPLLLLEEIEKENKRFQEDREFSAGTVYPETNKTKNKGVYSSTNE 420
           QEIVEKVIKVYGPSTEPLLLLEEIEKENKRFQEDREFSAGTVYPETNKTKNKGVYSSTNE
Sbjct: 361 QEIVEKVIKVYGPSTEPLLLLEEIEKENKRFQEDREFSAGTVYPETNKTKNKGVYSSTNE 420

Query: 421 LTTDSTPKKTQAHTQQNMVEKFSQLPFKVEAKPCTSNCRINTFRTVPIEQKHEVWGSNQN 480
           LTTDSTPKKTQAHTQQNMVEKFSQLPFKVEAKPCTSNCRINTFRTVPIEQKHEVWGSNQN
Sbjct: 421 LTTDSTPKKTQAHTQQNMVEKFSQLPFKVEAKPCTSNCRINTFRTVPIEQKHEVWGSNQN 480

Query: 481 YICNTDPETDGLSPSVASPSPKEVNFVSRGASSHQPRVPLFPENGLHQQPEPLLPNNMKS 540
           YICNTDPETDGLSPSVASPSPKEVNFVSRGASSHQPRVPLFPENGLHQQPEPLLPNNMKS
Sbjct: 481 YICNTDPETDGLSPSVASPSPKEVNFVSRGASSHQPRVPLFPENGLHQQPEPLLPNNMKS 540

Query: 541 ACEKRLGCCSSPHSKPNCSTLSPPMPLPQLLPSVTDARSAGPSDHIDSSVTGVQRFRDTL 600
           ACEKRLGCCSSPHSKPNCSTLSPPMPLPQLLPSVTDARSAGPSDHIDSSVTGVQRFRDTL
Sbjct: 541 ACEKRLGCCSSPHSKPNCSTLSPPMPLPQLLPSVTDARSAGPSDHIDSSVTGVQRFRDTL 600

Query: 601 KIPYKLELKNEPGRTDLKHIVIDGSNVAITHGLKKFFSCRGIAIAVEYFWKLGNRNITVF 660
           KIPYKLELKNEPGRTDLKHIVIDGSNVAITHGLKKFFSCRGIAIAVEYFWKLGNRNITVF
Sbjct: 601 KIPYKLELKNEPGRTDLKHIVIDGSNVAITHGLKKFFSCRGIAIAVEYFWKLGNRNITVF 660

Query: 661 VPQWRTRRDPNVTEQHFLTQLQELGILSLTPARMVFGERIASHDDRFLLHLADKTGGIIV 720
           VPQWRTRRDPNVTEQHFLTQLQELGILSLTPARMVFGERIASHDDRFLLHLADKTGGIIV
Sbjct: 661 VPQWRTRRDPNVTEQHFLTQLQELGILSLTPARMVFGERIASHDDRFLLHLADKTGGIIV 720

Query: 721 TNDNFREFVNESVSWREIITKRLLQYTFVGDIFMVPDDPLGRSGPRLEEFLQKEVCLRDM 780
           TNDNFREFVNESVSWREIITKRLLQYTFVGDIFMVPDDPLGRSGPRLEEFLQKEVCLRDM
Sbjct: 721 TNDNFREFVNESVSWREIITKRLLQYTFVGDIFMVPDDPLGRSGPRLEEFLQKEVCLRDM 780

Query: 781 QPLLSALPNVGMFDPSFRVPGTQAASTSHQPPTRIQGAPSSHWLPQQPHFPLLPALPSLQ 840
           QPLLSALPNVGMFDPSFRVPGTQAASTSHQPPTRIQGAPSSHWLPQQPHFPLLPALPSLQ
Sbjct: 781 QPLLSALPNVGMFDPSFRVPGTQAASTSHQPPTRIQGAPSSHWLPQQPHFPLLPALPSLQ 840

Query: 841 QNLPMPAQRSSAETNELREALLKIFPDSEQRLKIDQILVAHPYMKDLNALSAMVLD 896
           QNLPMPAQRSSAETNELREALLKIFPDSEQRLKIDQILVAHPYMKDLNALSAMVLD
Sbjct: 841 QNLPMPAQRSSAETNELREALLKIFPDSEQRLKIDQILVAHPYMKDLNALSAMVLD 896


>gi|54792090 hypothetical protein LOC23351 [Homo sapiens]
          Length = 678

 Score =  252 bits (644), Expect = 1e-66
 Identities = 140/306 (45%), Positives = 187/306 (61%), Gaps = 41/306 (13%)

Query: 590 VTGVQRFRDTLKIPYKLELKNEPGRTDLKHIVIDGSNVAITHGLKKFFSCRGIAIAVEYF 649
           VTG QRF++ L+ P+ L L N PG+ DL+HIVIDGSNVA+ HGL+ +FS RGIAIAV+YF
Sbjct: 410 VTGTQRFKEALQDPFTLCLANVPGQPDLRHIVIDGSNVAMVHGLQHYFSSRGIAIAVQYF 469

Query: 650 WKLGNRNITVFVPQWRTRRDPNVTEQHFLTQLQELGILSLTPARMVFGERIASHDDRFLL 709
           W  G+R+ITVFVPQWR  +D  V E HFL +L  L +LSLTP+R++ G+RI+S+DDRF++
Sbjct: 470 WDRGHRDITVFVPQWRFSKDAKVRESHFLQKLYSLSLLSLTPSRVMDGKRISSYDDRFMV 529

Query: 710 HLADKTGGIIVTNDNFREFVNESVSWREIITKRLLQYTFVGDIFMVPDDPLGRSGPRLEE 769
            LA++T GIIV+ND FR+   ES  W  II +RLL +TFVG++FMVPDDPLGR+GP L+E
Sbjct: 530 KLAEETDGIIVSNDQFRDLAEESEKWMAIIRERLLPFTFVGNLFMVPDDPLGRNGPTLDE 589

Query: 770 FLQKEVCLRDMQPLLSALPNVGMFDPSFRVPGTQAASTSHQPPTRIQGAPSSHWLPQQPH 829
           FL+K                          P     S+  Q P+R     + H   QQ  
Sbjct: 590 FLKK--------------------------PARTQGSSKAQHPSR---GFAEHGKQQQ-- 618

Query: 830 FPLLPALPSLQQNLPMPAQRSSAETNELREALLKIFPDSEQRLKIDQILVAHPYMKDLNA 889
                     ++       R + ET  LR  LL++F   +   K+D IL   PY +D+N 
Sbjct: 619 --------GREEEKGSGGIRKTRETERLRRQLLEVFWGQDH--KVDFILQREPYCRDINQ 668

Query: 890 LSAMVL 895
           LS  +L
Sbjct: 669 LSEALL 674



 Score =  106 bits (265), Expect = 8e-23
 Identities = 68/187 (36%), Positives = 102/187 (54%), Gaps = 6/187 (3%)

Query: 8   DEFTAPAEKAELLEQSRGRIEGLFGVSLAVLGALGAEEPLPARIWLQLCGAQEAVHSAKE 67
           D F   AE    + + +  +E +F V ++VL     + P    IWLQL G +E    AKE
Sbjct: 12  DRFAVSAEAENKVREQQPHVERIFSVGVSVLPKDCPDNP---HIWLQLEGPKENASRAKE 68

Query: 68  YIKGICEPELEERECYPKDMHCIFVGAESLFLKSLIQDTCADLCILDIGLLGIRGSAEAV 127
           Y+KG+C PEL++   YP  +HCIF+GA+  FL  L   T A L     G L I G  EA 
Sbjct: 69  YLKGLCSPELQDEIHYPPKLHCIFLGAQGFFLDCLAWSTSAHLVPRAPGSLMISGLTEAF 128

Query: 128 VMARSHIQQFV-KLFENKENLPSS--QKESEVKREFKQFVEAHADNYTMDLLILPTSLKK 184
           VMA+S +++   +L  +    PSS   + + V R+F   +++  D +   LL LP ++++
Sbjct: 129 VMAQSRVEELAERLSWDFTPGPSSGASQCTGVLRDFSALLQSPGDAHREALLQLPLAVQE 188

Query: 185 ELLTLTQ 191
           ELL+L Q
Sbjct: 189 ELLSLVQ 195


>gi|126723547 hypothetical protein LOC57523 [Homo sapiens]
          Length = 1898

 Score =  204 bits (518), Expect = 4e-52
 Identities = 96/194 (49%), Positives = 141/194 (72%), Gaps = 4/194 (2%)

Query: 582 PSDHI--DSSVTGVQRFRDTLKIPYKLELKNEPGRTDLKHIVIDGSNVAITHGLKKFFSC 639
           P  H+  +S+VT  QR+ + L  P++L L  EPG   L+ +VIDGS+VA+ HGL+ FFSC
Sbjct: 755 PPRHLQANSTVTSFQRYHEALNTPFELNLSGEPGNQGLRRVVIDGSSVAMVHGLQHFFSC 814

Query: 640 RGIAIAVEYFWKLGNRNITVFVPQWRTRRDPNVTEQHFLTQLQELGILSLTPARMVFGER 699
           RGIA+AV++FW  G+R +TVFVP W+ +++  V E HFLT+L  L +LS+TP+++  G++
Sbjct: 815 RGIAMAVQFFWNRGHREVTVFVPTWQLKKNRRVRESHFLTKLHSLKMLSITPSQLENGKK 874

Query: 700 IASHDDRFLLHLADKTGGIIVTNDNFREFVNESVSWREIITKRLLQYTFVGDIFMVPDDP 759
           I ++D RF++ LA++T GIIVTN+     +N S   + ++  RLL +TF G++FMVPDDP
Sbjct: 875 ITTYDYRFMVKLAEETDGIIVTNEQIHILMNSSK--KLMVKDRLLPFTFAGNLFMVPDDP 932

Query: 760 LGRSGPRLEEFLQK 773
           LGR GP L+EFL+K
Sbjct: 933 LGRDGPTLDEFLKK 946



 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 70/229 (30%), Positives = 109/229 (47%), Gaps = 20/229 (8%)

Query: 10  FTAPAEKAELLEQSRGRIEGLFGVSLAVLGALGAEEPLPARIWLQLCGAQEAVHSAKEYI 69
           F    +    +++ R +++ +F V L    +     P     WLQL G +E +  AKEY+
Sbjct: 14  FMVQTKSKPRVQRQRLQVQRIFRVKLNAFQS----RPDTPYFWLQLEGPRENMGKAKEYL 69

Query: 70  KGICEPELEERECYPKDMHCIFVGAESLFLKSLIQDTCADLCILDIGLLGIRGSAEAVVM 129
           KG+C PEL +   YP  +HC F+GA+ LFL  L   T A L     G L + G  E+ +M
Sbjct: 70  KGLCSPELWKEVRYPPILHCAFLGAQGLFLDCLCWSTLAYLVPGPPGSLMVGGLTESFIM 129

Query: 130 ARSHIQQFV-KLFENKENL--PSSQKESEVKREFKQFVEAHADNYTMDLLILPTSLKKEL 186
            ++ +++ V +L      L  P    E+EV R F   V    D +  DLL LP ++++ L
Sbjct: 130 TQNWLEELVGRLRWGPAPLLTPRGIWEAEVTRAFGALVWIRGDQHAGDLLQLPPAVQELL 189

Query: 187 LTLTQ---GEENLFE----------TGDDEVIEMRDSQQTEFTQNAATG 222
           L+L +   G+E++ E            D EV+     QQ E     + G
Sbjct: 190 LSLVRDAAGKEDIIEWLSRFGISDSHSDPEVLICPPQQQKEAPAMVSVG 238


>gi|148886668 zinc finger CCCH-type containing 12C [Homo sapiens]
          Length = 883

 Score =  176 bits (445), Expect = 1e-43
 Identities = 85/162 (52%), Positives = 120/162 (74%), Gaps = 3/162 (1%)

Query: 616 DLKHIVIDGSNVAITHGLKKFFSCRGIAIAVEYFWKLGNRNITVFVPQWR---TRRDPNV 672
           +L+ IVIDGSNVA++HG K+ FSCRGI +AV++F + G+++ITVFVP WR   +R D  +
Sbjct: 244 NLRPIVIDGSNVAMSHGNKEVFSCRGIKLAVDWFLERGHKDITVFVPAWRKEQSRPDALI 303

Query: 673 TEQHFLTQLQELGILSLTPARMVFGERIASHDDRFLLHLADKTGGIIVTNDNFREFVNES 732
           T+Q  L +L++  IL  TP+R V G R+  +DDRF++ LA ++ GIIV+NDN+R+  NE 
Sbjct: 304 TDQEILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFESDGIIVSNDNYRDLANEK 363

Query: 733 VSWREIITKRLLQYTFVGDIFMVPDDPLGRSGPRLEEFLQKE 774
             W++ I +RLL Y+FV D FM PDDPLGR GP L+ FL+K+
Sbjct: 364 PEWKKFIDERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKK 405



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 35/165 (21%), Positives = 67/165 (40%), Gaps = 12/165 (7%)

Query: 272 DEEALSNERICQKRRFSDSEERHTKKQFSLENVQEGEILHDAKTLAGNVIAD--LSDSSA 329
           DE+  S E         ++   H  +Q    +V+ G I    + L  +   +  +   + 
Sbjct: 76  DEKEASEENASSGDSEENTNSDHESEQLGSISVEPGLITKTHRQLCRSPCLEPHILKRNE 135

Query: 330 DSENLSPDIKETTEE---------MEYNILVNFFKTMGYSQEIVEKVIKVYGPSTEPLLL 380
             ++  P+  +TT +          EY   + F   +GYS+E V+ V+   G       +
Sbjct: 136 ILQDFKPEESQTTSKEAKKPPDVVREYQTKLEFALKLGYSEEQVQLVLNKLGTDALINDI 195

Query: 381 LEEIEKENKRFQEDREFSA-GTVYPETNKTKNKGVYSSTNELTTD 424
           L E+ K   + + D+  S   T+  ET+  +++   S   E+ TD
Sbjct: 196 LGELVKLGNKSEADQTVSTINTITRETSSLESQRSESPMQEIVTD 240


>gi|156151383 zinc finger CCCH-type containing 12A [Homo sapiens]
          Length = 599

 Score =  173 bits (439), Expect = 6e-43
 Identities = 84/169 (49%), Positives = 119/169 (70%), Gaps = 3/169 (1%)

Query: 609 KNEPGRTDLKHIVIDGSNVAITHGLKKFFSCRGIAIAVEYFWKLGNRNITVFVPQWRT-- 666
           + E   +DL+ +VIDGSNVA++HG K+ FSCRGI +AV +F + G+ +ITVFVP WR   
Sbjct: 127 EEEKEGSDLRPVVIDGSNVAMSHGNKEVFSCRGILLAVNWFLERGHTDITVFVPSWRKEQ 186

Query: 667 -RRDPNVTEQHFLTQLQELGILSLTPARMVFGERIASHDDRFLLHLADKTGGIIVTNDNF 725
            R D  +T+QH L +L++  IL  TP+R V G+R+  +DDRF++ LA ++ GI+V+ND +
Sbjct: 187 PRPDVPITDQHILRELEKKKILVFTPSRRVGGKRVVCYDDRFIVKLAYESDGIVVSNDTY 246

Query: 726 REFVNESVSWREIITKRLLQYTFVGDIFMVPDDPLGRSGPRLEEFLQKE 774
           R+   E   W+  I +RLL Y+FV D FM PDDPLGR GP L+ FL+K+
Sbjct: 247 RDLQGERQEWKRFIEERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKK 295



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 15/59 (25%), Positives = 29/59 (49%)

Query: 340 ETTEEMEYNILVNFFKTMGYSQEIVEKVIKVYGPSTEPLLLLEEIEKENKRFQEDREFS 398
           E    +E  + V+FF+ +GYS   +  V++  G   +   +L E+ K     + +R+ S
Sbjct: 41  EEASALELQMKVDFFRKLGYSSTEIHSVLQKLGVQADTNTVLGELVKHGTATERERQTS 99


>gi|148746187 zinc finger CCCH-type containing 12B [Homo sapiens]
          Length = 825

 Score =  172 bits (435), Expect = 2e-42
 Identities = 88/173 (50%), Positives = 123/173 (71%), Gaps = 4/173 (2%)

Query: 605 KLELKNEPGRTD-LKHIVIDGSNVAITHGLKKFFSCRGIAIAVEYFWKLGNRNITVFVPQ 663
           +L L++E   +D L+ +VIDGSNVA++HG K+ FSCRGI +AV++F   G+++ITVFVP 
Sbjct: 166 ELSLEDEIDNSDNLRPVVIDGSNVAMSHGNKEEFSCRGIQLAVDWFLDKGHKDITVFVPA 225

Query: 664 WR---TRRDPNVTEQHFLTQLQELGILSLTPARMVFGERIASHDDRFLLHLADKTGGIIV 720
           WR   +R D  +T+Q  L +L++  IL  TP+R V G R+  +DDRF++ LA  + GIIV
Sbjct: 226 WRKEQSRPDAPITDQDILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIV 285

Query: 721 TNDNFREFVNESVSWREIITKRLLQYTFVGDIFMVPDDPLGRSGPRLEEFLQK 773
           +NDN+R+   E   W++ I +RLL Y+FV D FM PDDPLGR GP LE FL+K
Sbjct: 286 SNDNYRDLQVEKPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRK 338


>gi|148762945 zinc finger CCCH-type containing 12D [Homo sapiens]
          Length = 321

 Score =  162 bits (409), Expect = 2e-39
 Identities = 78/163 (47%), Positives = 112/163 (68%), Gaps = 3/163 (1%)

Query: 615 TDLKHIVIDGSNVAITHGLKKFFSCRGIAIAVEYFWKLGNRNITVFVPQWRT---RRDPN 671
           + L+ IVIDGSNVA++HG K+ FSCRGI +AV++F   G+  I VFVP WR    R D  
Sbjct: 87  SSLRPIVIDGSNVAMSHGNKETFSCRGIKLAVDWFRDRGHTYIKVFVPSWRKDSPRADTP 146

Query: 672 VTEQHFLTQLQELGILSLTPARMVFGERIASHDDRFLLHLADKTGGIIVTNDNFREFVNE 731
           + EQH L +L+   +L  TP+R V G+R+  +DDR+++ +A +  G+IV+NDN+R+  +E
Sbjct: 147 IREQHVLAELERQAVLVYTPSRKVHGKRLVCYDDRYIVKVAYEQDGVIVSNDNYRDLQSE 206

Query: 732 SVSWREIITKRLLQYTFVGDIFMVPDDPLGRSGPRLEEFLQKE 774
           +  W+  I +RLL ++FV D FM PDDPLGR GP L  FL ++
Sbjct: 207 NPEWKWFIEQRLLMFSFVNDRFMPPDDPLGRHGPSLSNFLSRK 249


>gi|65507253 hypothetical protein LOC55196 [Homo sapiens]
          Length = 1747

 Score = 40.0 bits (92), Expect = 0.010
 Identities = 51/230 (22%), Positives = 97/230 (42%), Gaps = 21/230 (9%)

Query: 144  KENLPSSQKESEVKREFKQFVEAHADNYTMDLLILPTSLKKELLTLTQGEENLFETGDDE 203
            K+++  + +  + K  F    + +  + ++   + P  +K +L +++  ++   + G+  
Sbjct: 1324 KKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKRKLDQGNVL 1383

Query: 204  VIEMRDSQQTEFTQNAATGLNISRDETVLQEEARNKAGTPVSELTKQMDTVLSSSPDVLF 263
             +E++  +  +  Q  + G      +++     R      +   TK +DT  SSS    F
Sbjct: 1384 DMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKEKMVSNTKSVDTKASSSK---F 1440

Query: 264  DPINGLTPDE--------EALSN---ERICQKRRFSDSEE-RHTKKQFSLENVQEGEILH 311
              I  LTP E        EALSN   ++IC K    DSE  R +K    +E+  +    H
Sbjct: 1441 SRI--LTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEHMRPSKLAVQVESCGKSNEKH 1498

Query: 312  DAKTLAGNVIADLSDSSADSENLSPDIKETTEEMEYNILVNFFKTMGYSQ 361
             +          L+  ++  +NL   I  + E   YNIL N  + +G  Q
Sbjct: 1499 SSGVQTSK--ESLNGLTSHGKNLK--IHHSQESKTYNILRNVKEKVGGKQ 1544


>gi|54112394 calcium channel, voltage-dependent, alpha 2/delta
           subunit 2 isoform b [Homo sapiens]
          Length = 1143

 Score = 39.7 bits (91), Expect = 0.013
 Identities = 37/143 (25%), Positives = 64/143 (44%), Gaps = 11/143 (7%)

Query: 254 VLSSSPDVLFDPINGLTPDEEALSNERICQKRRFSDSEERHTKKQFSLENVQEGEILH-D 312
           V  + P  L + + G   D E+L + ++   +R +D+ E   K     +N++E +I++ D
Sbjct: 107 VQENEPQKLVEKVAG---DIESLLDRKVQALKRLADAAENFQKAHRWQDNIKEEDIVYYD 163

Query: 313 AKTLAGNVIADLSDSSADSENLSPDIKETTEEMEYNILVNFFKTMGYSQEIVEKVIKVYG 372
           AK       AD      +SE++    K +T  +++    NF   + YS   V+    +Y 
Sbjct: 164 AK-------ADAELDDPESEDVERGSKASTLRLDFIEDPNFKNKVNYSYAAVQIPTDIYK 216

Query: 373 PSTEPLLLLEEIEKENKRFQEDR 395
            ST  L  L   E     F E+R
Sbjct: 217 GSTVILNELNWTEALENVFMENR 239


>gi|54112392 calcium channel, voltage-dependent, alpha 2/delta
           subunit 2 isoform a [Homo sapiens]
          Length = 1145

 Score = 39.7 bits (91), Expect = 0.013
 Identities = 37/143 (25%), Positives = 64/143 (44%), Gaps = 11/143 (7%)

Query: 254 VLSSSPDVLFDPINGLTPDEEALSNERICQKRRFSDSEERHTKKQFSLENVQEGEILH-D 312
           V  + P  L + + G   D E+L + ++   +R +D+ E   K     +N++E +I++ D
Sbjct: 107 VQENEPQKLVEKVAG---DIESLLDRKVQALKRLADAAENFQKAHRWQDNIKEEDIVYYD 163

Query: 313 AKTLAGNVIADLSDSSADSENLSPDIKETTEEMEYNILVNFFKTMGYSQEIVEKVIKVYG 372
           AK       AD      +SE++    K +T  +++    NF   + YS   V+    +Y 
Sbjct: 164 AK-------ADAELDDPESEDVERGSKASTLRLDFIEDPNFKNKVNYSYAAVQIPTDIYK 216

Query: 373 PSTEPLLLLEEIEKENKRFQEDR 395
            ST  L  L   E     F E+R
Sbjct: 217 GSTVILNELNWTEALENVFMENR 239


>gi|239755810 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 499

 Score = 39.3 bits (90), Expect = 0.017
 Identities = 34/103 (33%), Positives = 47/103 (45%), Gaps = 12/103 (11%)

Query: 492 LSPSVASPSPKEVNFVSRGAS--SHQPRVPLFPE-NGLHQQPEPLLPNNMKSACEKRLGC 548
           LSP++ +PSP+EV   S   +  S +P  P   E N     P PL P         R G 
Sbjct: 394 LSPALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLGP------LRPRAGG 447

Query: 549 CSSPHSKPNCSTLSPPMPLPQLLPSVTDARSAGPSDHIDSSVT 591
            SS H      T++ P P+P      T A   GPS H++++ T
Sbjct: 448 QSSGHPD---RTVTSPRPIPARPRPRTSASRPGPSPHLEATGT 487


>gi|239750310 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 499

 Score = 39.3 bits (90), Expect = 0.017
 Identities = 34/103 (33%), Positives = 47/103 (45%), Gaps = 12/103 (11%)

Query: 492 LSPSVASPSPKEVNFVSRGAS--SHQPRVPLFPE-NGLHQQPEPLLPNNMKSACEKRLGC 548
           LSP++ +PSP+EV   S   +  S +P  P   E N     P PL P         R G 
Sbjct: 394 LSPALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLGP------LRPRAGG 447

Query: 549 CSSPHSKPNCSTLSPPMPLPQLLPSVTDARSAGPSDHIDSSVT 591
            SS H      T++ P P+P      T A   GPS H++++ T
Sbjct: 448 QSSGHPD---RTVTSPRPIPARPRPRTSASRPGPSPHLEATGT 487


>gi|239744621 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 536

 Score = 39.3 bits (90), Expect = 0.017
 Identities = 34/103 (33%), Positives = 47/103 (45%), Gaps = 12/103 (11%)

Query: 492 LSPSVASPSPKEVNFVSRGAS--SHQPRVPLFPE-NGLHQQPEPLLPNNMKSACEKRLGC 548
           LSP++ +PSP+EV   S   +  S +P  P   E N     P PL P         R G 
Sbjct: 431 LSPALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLGP------LRPRAGG 484

Query: 549 CSSPHSKPNCSTLSPPMPLPQLLPSVTDARSAGPSDHIDSSVT 591
            SS H      T++ P P+P      T A   GPS H++++ T
Sbjct: 485 QSSGHPD---RTVTSPRPIPARPRPRTSASRPGPSPHLEATGT 524


>gi|22095367 centrosomal protein 63 isoform a [Homo sapiens]
          Length = 703

 Score = 38.9 bits (89), Expect = 0.022
 Identities = 94/479 (19%), Positives = 179/479 (37%), Gaps = 90/479 (18%)

Query: 147 LPSSQKESEVKREFKQFVEAHADNYTMDLLILPTSLKKELLTLTQGEENLFETGDDEVIE 206
           L   Q++ E  RE ++ +EA  +             K+EL    Q +ENL      +  +
Sbjct: 245 LQEQQQKEEKLRESEKLLEALQEE------------KRELKAALQSQENLIHEARIQKEK 292

Query: 207 MRDSQQTEFTQNAATGLNISRDETVLQEEARNKAGTPVSELTKQMDTVLSSSPDVLFDPI 266
           +++  +   TQ+A   +   R+E++ +++  ++    +  +  Q++    +S D+L   +
Sbjct: 293 LQEKVKATNTQHAVEAIR-PREESLAEKKYTSQGQGDLDSVLSQLN-FTHTSEDLLQAEV 350

Query: 267 NGLTPDEEALSNERICQKRRFSDSEERHTKKQFSLENVQEGEILHDAKTLAGNVIADLSD 326
             L    E++S    C++      E+    K+    N    E   + K L   ++     
Sbjct: 351 TCLEGSLESVS--ATCKQLSQELMEKYEELKRMEAHN---NEYKAEIKKLKEQILQGEQS 405

Query: 327 SSADSENLSPDIKETTEEMEYNILVNFFKTMGYSQEIVEK----VIKVYGPSTEPLLLLE 382
            S+  E +  +I   T+E+     +    T G S ++ ++    + K    + E   +L+
Sbjct: 406 YSSALEGMKMEISHLTQELHQRD-ITIASTKGSSSDMEKRLRAEMQKAEDKAVEHKEILD 464

Query: 383 EIEK---ENKR-----------FQEDREFSAGTVYPETNKTKNKGVYSSTNELTTDSTPK 428
           ++E    EN+              E +E S   +     +  NK + S   +L  D    
Sbjct: 465 QLESLKLENRHLSEMVMKLELGLHEAKEISLADLQENYIEALNK-LVSENQQLQKDLMNT 523

Query: 429 KTQAHTQQNMVEKFSQLPFKVEAKPCTSNCRINTFRTVPIEQKHEVWGSNQNYICNTDP- 487
           K+Q      M +K +   FK       ++ R   F+    +  H   G +++    T+  
Sbjct: 524 KSQLEISTQMCKKQNDRIFK------PTHSRTTEFKNTEFKPTH---GQHRHDGIKTEHY 574

Query: 488 ETDGLSPSVASPSPKEVNFVSRGASSHQPRVPLFPENGLHQQPEPLLPNNMKSACEKRLG 547
           +TD  SP     +   +N +SR  S      PL P+                      + 
Sbjct: 575 KTDLHSP--RGQASDSINPMSRVLS------PLSPQ----------------------IS 604

Query: 548 CCSSPHSKPN---CSTLSPPMPLPQLLPSVTDARSAGPSDHIDSSVTGVQRFRDTLKIP 603
            CSS  S  +   C T S        LPS  D   A  SD +  S+   + F  +  +P
Sbjct: 605 PCSSTRSLTSYSLCKTHS--------LPSALDTNEANFSDTMSESMNDQEEFISSCSLP 655


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 37.7 bits (86), Expect = 0.048
 Identities = 54/292 (18%), Positives = 115/292 (39%), Gaps = 33/292 (11%)

Query: 129  MARSHIQQFVKLFENKENLPSSQKESEVKREFKQFVEAHADNYTMDLLILPTSLKKELLT 188
            +A+   +Q V + + +E L   +K  +   + K+ ++    +    +  L   + +  L 
Sbjct: 1025 LAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQ 1084

Query: 189  LTQGEENL---FETGDDEVIEMRDSQQTEFTQNAATGLNISRDETVLQEEARNKAGTPVS 245
            L + EE L      GDDE +   ++ +    +     +   +++   ++ +RNKA     
Sbjct: 1085 LAKKEEELQGALARGDDETLHKNNALKV--VRELQAQIAELQEDFESEKASRNKAEKQKR 1142

Query: 246  ELTKQMDTVLSSSPDVLFDPI----------NGLTPDEEALSNERICQKRRFSDSEERHT 295
            +L+++++ + +   D L                +   ++AL  E    + +  D  +RH 
Sbjct: 1143 DLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHA 1202

Query: 296  KKQFSLENVQEGEILHDAKTLAGNVIADLSDSSADSENLSPDIK---ETTEEMEYN---- 348
                +LE + E   L  AK    N+  +      D++ L+ ++K   +   E E+     
Sbjct: 1203 T---ALEELSEQ--LEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKL 1257

Query: 349  ------ILVNFFKTMGYSQEIVEKVIKVYGPSTEPLLLLEEIEKENKRFQED 394
                  +     +      E+ EK  K+         LLEE EK+  +F +D
Sbjct: 1258 DAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKD 1309


>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
          Length = 888

 Score = 37.0 bits (84), Expect = 0.082
 Identities = 33/165 (20%), Positives = 67/165 (40%), Gaps = 6/165 (3%)

Query: 185 ELLTLTQGEENLFETGDDEVIEMRDSQQTEFTQNAATGLNISRDETVLQEEARNKAGTPV 244
           E L     +++ F+ GD    E   +   + ++++  G     +E +L+EE         
Sbjct: 19  EALDYDSSDDSDFKVGDASDSEGSGNGSEDASKDSGEGSCSDSEENILEEELNEDIKVKE 78

Query: 245 SELTKQMDTVLSSSPDVLFDPINGLTPDEEALSNERICQKRRFSDSEERHTKKQFSLENV 304
            +L    +  + SS   L      +   EE  + ER   +++    +E+  +K+   E  
Sbjct: 79  EQLKNSAEEEVLSSEKQLIK----MEKKEEEENGER--PRKKKEKEKEKEKEKEKEKERE 132

Query: 305 QEGEILHDAKTLAGNVIADLSDSSADSENLSPDIKETTEEMEYNI 349
           +E E    ++ +A +  A    +S  + N SP +  TT   E  +
Sbjct: 133 KEKEKATVSENVAASAAATTPATSPPAVNTSPSVPTTTTATEEQV 177


>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
          Length = 948

 Score = 37.0 bits (84), Expect = 0.082
 Identities = 33/165 (20%), Positives = 67/165 (40%), Gaps = 6/165 (3%)

Query: 185 ELLTLTQGEENLFETGDDEVIEMRDSQQTEFTQNAATGLNISRDETVLQEEARNKAGTPV 244
           E L     +++ F+ GD    E   +   + ++++  G     +E +L+EE         
Sbjct: 19  EALDYDSSDDSDFKVGDASDSEGSGNGSEDASKDSGEGSCSDSEENILEEELNEDIKVKE 78

Query: 245 SELTKQMDTVLSSSPDVLFDPINGLTPDEEALSNERICQKRRFSDSEERHTKKQFSLENV 304
            +L    +  + SS   L      +   EE  + ER   +++    +E+  +K+   E  
Sbjct: 79  EQLKNSAEEEVLSSEKQLIK----MEKKEEEENGER--PRKKKEKEKEKEKEKEKEKERE 132

Query: 305 QEGEILHDAKTLAGNVIADLSDSSADSENLSPDIKETTEEMEYNI 349
           +E E    ++ +A +  A    +S  + N SP +  TT   E  +
Sbjct: 133 KEKEKATVSENVAASAAATTPATSPPAVNTSPSVPTTTTATEEQV 177


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 91/404 (22%), Positives = 158/404 (39%), Gaps = 57/404 (14%)

Query: 138  VKLFENKENLPSSQKESEVKREFKQFVEAHADNYTMDLLILPTSLKKELLTLTQGEENLF 197
            V+L E K+      +ES  K++ ++ ++A   +   + L    SL++EL       E L 
Sbjct: 1459 VELCEMKQKPEEIGEESRAKQQIQRKLQAALIS-RKEALKENKSLQEELSLARGTIERLT 1517

Query: 198  ETGDDEVIEMRDSQQTEFTQNAATGLNISRDETVLQEEARNKAGTPVSELTKQMDTVLSS 257
            ++       + D +     QN      + R    L +E R+K  T +     +  + LSS
Sbjct: 1518 KS-------LADVESQVSAQNKEKDTVLGR--LALLQEERDKLITEMDRSLLENQS-LSS 1567

Query: 258  SPDVLFDPINGLTPDEEALSNE-RICQKRRFSDS---EERHTKKQ-------FSLENV-Q 305
            S + L   + GLT D+E L  E    +  + ++S   +E+H + Q        S ENV  
Sbjct: 1568 SCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSN 1627

Query: 306  EGE----ILHDAKTLAGNVIADLSDSSADSENLSPDIKETTEEMEYNILVNFFKTMGYSQ 361
            E E    ++   +     +   L  + A+ +     ++E  +EME               
Sbjct: 1628 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEME--------------- 1672

Query: 362  EIVEKVIKVYGPSTEPLLLLEEIEKENKRFQEDREFSAGTVYPETNKTKNKGVYSSTNEL 421
            E+ EK+ K      + +L   E+E+EN R + +    AG    E  +T      S   EL
Sbjct: 1673 EMKEKMRKFAKSKQQKIL---ELEEENDRLRAE-VHPAGDTAKECMETLLSSNASMKEEL 1728

Query: 422  TTDSTPKKTQAHTQQNMVEKFSQLPFKVEAKPCTSNCRINTFRTVPIEQKHE----VWGS 477
                   +T +   Q+++ +   L  +V+         ++    +   +KH+    V   
Sbjct: 1729 ERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEE 1788

Query: 478  NQNYICNTDPETDGLSPSV------ASPSPKEVN-FVSRGASSH 514
                I     E D LS S       + PS K  N  VS+  SSH
Sbjct: 1789 GTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSH 1832


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 36.2 bits (82), Expect = 0.14
 Identities = 62/324 (19%), Positives = 128/324 (39%), Gaps = 40/324 (12%)

Query: 76   ELEERECYPKDMHCIFVGAESLFLKSLIQDTCADLCILDIGLLGIRGSAEAVVMARSHIQ 135
            E+EE     + MH  FV   S  +  L +DT A   ++   L  +    + + +    ++
Sbjct: 862  EIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVE 921

Query: 136  ----QFVKLFENKENLPSSQKESEV--------KREFKQFV--------EAHADNYTMDL 175
                +  +L ++   L  S KE ++        K+E    +        E   +N T  L
Sbjct: 922  TEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGT--L 979

Query: 176  LILPTSLKKELLTLTQGEE---NLFETGDDEVIEMRDSQQTEFTQNAATGLNISR-DETV 231
              +  SL +E + L Q  E   N  +  +  + E+ D  + E        + + R +ET 
Sbjct: 980  KEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKL------ILLQRCEETG 1033

Query: 232  LQEEARNKAGTPVSELTKQMDTVLSSSPDVLFDPINGLTPDEEALSNERICQKRRFSDSE 291
               E  ++      E   +++ +L+    +  +  N L   +EA + E      + + +E
Sbjct: 1034 NAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAE 1093

Query: 292  ERHTKKQFSLENVQEG------EILHDAKTLAGNVIADLSDSSADSENLSPDIKETTEEM 345
            ER+      LE VQ+       +  +++K+ AG +  ++     +   +  ++ +  +E 
Sbjct: 1094 ERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQEN 1153

Query: 346  EYNILVNFFKTMGYSQEIVEKVIK 369
            E   L+   KT    Q +  + I+
Sbjct: 1154 EQ--LMKVMKTKHECQNLESEPIR 1175


>gi|17865632 mitochondrial tumor suppressor 1 isoform 5 [Homo
           sapiens]
          Length = 436

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 64/296 (21%), Positives = 116/296 (39%), Gaps = 63/296 (21%)

Query: 123 SAEAVVMARSHIQQFVKLFENKENLPSSQKESEVKREFKQFVEAHADNYTMDLLILPTSL 182
           + E +  AR+ +Q   + F  +     +++E+ +K  + +  E   D Y  +       L
Sbjct: 140 TCEKLEKARNELQTVYEAFVQQHQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQL 199

Query: 183 KKELLTLTQGEENLFETGDDEVIEMRDSQQTEFTQNAATGLNISRDETVLQEEARNKAGT 242
           +++   L    E          IE   S++ E  + A         E  L E    K G 
Sbjct: 200 QEQFDNLNAAHET-----SKLEIEASHSEKLELLKKAY--------EASLSEI---KKGH 243

Query: 243 PVSELTKQMDTVLSSSPDVLFDPINGLTPDEEALSNERICQKRRFSDSEERHTKKQFSLE 302
            + +  K ++ +LS   + L   IN L  + +AL NE++      S+ ++R  +++ +L+
Sbjct: 244 EIEK--KSLEDLLSEKQESLEKQINDLKSENDAL-NEKLK-----SEEQKRRAREKANLK 295

Query: 303 NVQ-----------------EGEILH--DAKTLAGNVIADLSDSSADSENLSPDIKETTE 343
           N Q                 + E LH  D K +    + D + +  D       +K   +
Sbjct: 296 NPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTALVDK------LKRFQQ 349

Query: 344 EMEYNILVNFFKTMGYSQEIVEKVIKVYGPSTEPLLLLEEIEKE---NKRFQEDRE 396
           E E  +     K M  S+++          STE  +L E +EKE   NKR   + E
Sbjct: 350 ENE-ELKARMDKHMAISRQL----------STEQAVLQESLEKESKVNKRLSMENE 394


>gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sapiens]
          Length = 1270

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 64/296 (21%), Positives = 116/296 (39%), Gaps = 63/296 (21%)

Query: 123  SAEAVVMARSHIQQFVKLFENKENLPSSQKESEVKREFKQFVEAHADNYTMDLLILPTSL 182
            + E +  AR+ +Q   + F  +     +++E+ +K  + +  E   D Y  +       L
Sbjct: 974  TCEKLEKARNELQTVYEAFVQQHQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQL 1033

Query: 183  KKELLTLTQGEENLFETGDDEVIEMRDSQQTEFTQNAATGLNISRDETVLQEEARNKAGT 242
            +++   L    E          IE   S++ E  + A         E  L E    K G 
Sbjct: 1034 QEQFDNLNAAHET-----SKLEIEASHSEKLELLKKAY--------EASLSEI---KKGH 1077

Query: 243  PVSELTKQMDTVLSSSPDVLFDPINGLTPDEEALSNERICQKRRFSDSEERHTKKQFSLE 302
             + +  K ++ +LS   + L   IN L  + +AL NE++      S+ ++R  +++ +L+
Sbjct: 1078 EIEK--KSLEDLLSEKQESLEKQINDLKSENDAL-NEKLK-----SEEQKRRAREKANLK 1129

Query: 303  NVQ-----------------EGEILH--DAKTLAGNVIADLSDSSADSENLSPDIKETTE 343
            N Q                 + E LH  D K +    + D + +  D       +K   +
Sbjct: 1130 NPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTALVDK------LKRFQQ 1183

Query: 344  EMEYNILVNFFKTMGYSQEIVEKVIKVYGPSTEPLLLLEEIEKE---NKRFQEDRE 396
            E E  +     K M  S+++          STE  +L E +EKE   NKR   + E
Sbjct: 1184 ENE-ELKARMDKHMAISRQL----------STEQAVLQESLEKESKVNKRLSMENE 1228


>gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo sapiens]
          Length = 1216

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 64/296 (21%), Positives = 116/296 (39%), Gaps = 63/296 (21%)

Query: 123  SAEAVVMARSHIQQFVKLFENKENLPSSQKESEVKREFKQFVEAHADNYTMDLLILPTSL 182
            + E +  AR+ +Q   + F  +     +++E+ +K  + +  E   D Y  +       L
Sbjct: 920  TCEKLEKARNELQTVYEAFVQQHQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQL 979

Query: 183  KKELLTLTQGEENLFETGDDEVIEMRDSQQTEFTQNAATGLNISRDETVLQEEARNKAGT 242
            +++   L    E          IE   S++ E  + A         E  L E    K G 
Sbjct: 980  QEQFDNLNAAHET-----SKLEIEASHSEKLELLKKAY--------EASLSEI---KKGH 1023

Query: 243  PVSELTKQMDTVLSSSPDVLFDPINGLTPDEEALSNERICQKRRFSDSEERHTKKQFSLE 302
             + +  K ++ +LS   + L   IN L  + +AL NE++      S+ ++R  +++ +L+
Sbjct: 1024 EIEK--KSLEDLLSEKQESLEKQINDLKSENDAL-NEKLK-----SEEQKRRAREKANLK 1075

Query: 303  NVQ-----------------EGEILH--DAKTLAGNVIADLSDSSADSENLSPDIKETTE 343
            N Q                 + E LH  D K +    + D + +  D       +K   +
Sbjct: 1076 NPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTALVDK------LKRFQQ 1129

Query: 344  EMEYNILVNFFKTMGYSQEIVEKVIKVYGPSTEPLLLLEEIEKE---NKRFQEDRE 396
            E E  +     K M  S+++          STE  +L E +EKE   NKR   + E
Sbjct: 1130 ENE-ELKARMDKHMAISRQL----------STEQAVLQESLEKESKVNKRLSMENE 1174


>gi|50348626 mitochondrial tumor suppressor 1 isoform 4 [Homo
           sapiens]
          Length = 517

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 64/296 (21%), Positives = 116/296 (39%), Gaps = 63/296 (21%)

Query: 123 SAEAVVMARSHIQQFVKLFENKENLPSSQKESEVKREFKQFVEAHADNYTMDLLILPTSL 182
           + E +  AR+ +Q   + F  +     +++E+ +K  + +  E   D Y  +       L
Sbjct: 221 TCEKLEKARNELQTVYEAFVQQHQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQL 280

Query: 183 KKELLTLTQGEENLFETGDDEVIEMRDSQQTEFTQNAATGLNISRDETVLQEEARNKAGT 242
           +++   L    E          IE   S++ E  + A         E  L E    K G 
Sbjct: 281 QEQFDNLNAAHET-----SKLEIEASHSEKLELLKKAY--------EASLSEI---KKGH 324

Query: 243 PVSELTKQMDTVLSSSPDVLFDPINGLTPDEEALSNERICQKRRFSDSEERHTKKQFSLE 302
            + +  K ++ +LS   + L   IN L  + +AL NE++      S+ ++R  +++ +L+
Sbjct: 325 EIEK--KSLEDLLSEKQESLEKQINDLKSENDAL-NEKLK-----SEEQKRRAREKANLK 376

Query: 303 NVQ-----------------EGEILH--DAKTLAGNVIADLSDSSADSENLSPDIKETTE 343
           N Q                 + E LH  D K +    + D + +  D       +K   +
Sbjct: 377 NPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTALVDK------LKRFQQ 430

Query: 344 EMEYNILVNFFKTMGYSQEIVEKVIKVYGPSTEPLLLLEEIEKE---NKRFQEDRE 396
           E E  +     K M  S+++          STE  +L E +EKE   NKR   + E
Sbjct: 431 ENE-ELKARMDKHMAISRQL----------STEQAVLQESLEKESKVNKRLSMENE 475


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 60/288 (20%), Positives = 122/288 (42%), Gaps = 43/288 (14%)

Query: 182 LKKELLTLTQGEENLFETGDDEVIEMRDSQQTEFTQNAATGLNISRDETVLQEEARNKAG 241
           LKKEL+ +    +N+    + E  +++D  +   +Q A++   IS+  + L +  +  A 
Sbjct: 226 LKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVA- 284

Query: 242 TPVSELTKQMDTVLSSSPDVLFDPINGLTPDEEALSNERICQKRRFSDSEERHTKKQFSL 301
             V EL K     L SS       +N LT   + L+   + +++ ++  EE+H ++  S 
Sbjct: 285 VYVQELQK-----LKSS-------VNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSK 332

Query: 302 ENVQE------------GEILHDAKTLAGNVIADLSDSSADSENLSPDIKETTEEMEYNI 349
           +N+Q                L  ++T    +  +LS+    ++ L  ++ E   E +Y  
Sbjct: 333 KNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEV--ETKYQH 390

Query: 350 LVNFFKTMGYSQEIVEK-VIKVYGPSTEPLLLLEEIEKE----NKRFQEDREFSAGTVYP 404
           L   FK +   +E  E+  +++     +    L E E++    + R +E R+ S+  +  
Sbjct: 391 LKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMD 450

Query: 405 ETNKT-----KNKGVYSSTNELTTDST------PKKTQAHTQQNMVEK 441
           +  +      K   +     E  T+ST       K  Q H +Q  +++
Sbjct: 451 KEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQ 498


>gi|31982906 cingulin-like 1 [Homo sapiens]
          Length = 1302

 Score = 35.4 bits (80), Expect = 0.24
 Identities = 67/301 (22%), Positives = 132/301 (43%), Gaps = 29/301 (9%)

Query: 174  DLLILPTSLKKELLTLTQGEENLFETGDDEVIEMRDSQQTEFTQNAATGLNISRDETVLQ 233
            +L  L  +LK+E+ +  Q  + L E  D E+  +R+S + E T+N    +  SR  T  Q
Sbjct: 759  ELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVE-EATKNVE--VLASRSNTSEQ 815

Query: 234  EEARNKAGTPVS-ELTKQMDTVLSSSPDVLFDPINGLTPDEEALSNERICQKRRFS--DS 290
            ++    AGT +  +L ++ +  L    + L   +  L    E L  +    K      + 
Sbjct: 816  DQ----AGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEG 871

Query: 291  EERHTKKQFSLENVQEGEILHDAKTLAGNVIA---DLSDSSADSENLSPDIKETTEEMEY 347
            E R  ++       +E E +   + L   + A   +LS ++ + + LS  +KE +E+ E 
Sbjct: 872  EIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQ 931

Query: 348  ---------NILVNFFKTMGYSQEIVEKVIKVYGPSTEPLL-LLEEIEKENKR--FQEDR 395
                     N   +  KT+   Q+ +  +++    ST  L   L+E +++N+R   +  R
Sbjct: 932  LRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQR 991

Query: 396  EFSAGTVYPETNK---TKNKGVYSSTNELTTDSTPKKTQAHTQQNMVEK-FSQLPFKVEA 451
            +    T+  E ++    K +       E   D    + +A T++ ++E+    L +++EA
Sbjct: 992  QLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEA 1051

Query: 452  K 452
            K
Sbjct: 1052 K 1052


>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
          Length = 987

 Score = 35.0 bits (79), Expect = 0.31
 Identities = 53/250 (21%), Positives = 89/250 (35%), Gaps = 33/250 (13%)

Query: 349 ILVNFFKTMGYSQEIVEKVIKVYGPSTEPLLL-----LEEIEKENKRFQEDREFSAGTVY 403
           I  ++  T G SQ     + K  GPS+ P         +  E+  K+ +E+        +
Sbjct: 148 ITSSYSSTRGISQ-----LWKRNGPSSSPFSSPASSRSQTPERPAKKIREEE-----LCH 197

Query: 404 PETNKTKNKGVYSSTNELTTDSTPKKTQAHTQQNMVEKFSQLPFKVEAKPCTSNCRIN-- 461
             ++ T       S  E   D+TP+K Q    Q+      Q   KV+  P     ++   
Sbjct: 198 HSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLP 257

Query: 462 ---------TFRTVPIEQKHEVWGSNQNYICNTDPETDGLSPSVASPSPKEVNFVSRGAS 512
                    T   + +E+K  +   NQ     +D  ++ ++ +  +  P     +   A+
Sbjct: 258 PPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAAT 317

Query: 513 SHQPRVPLFPENGLHQQPEPLLPNNMKSACEKRLGCCSSPHSKPNCSTLSPPMPLPQLLP 572
           +  P   L P         PLL +  K      L  C           LSPP   P LLP
Sbjct: 318 ASPPTSLLAPST------NPLLESLKKMQTPPSLPPCPESAGAATTEALSPP-KTPSLLP 370

Query: 573 SVTDARSAGP 582
            +  ++S  P
Sbjct: 371 PLGLSQSGPP 380


>gi|4506105 prolactin precursor [Homo sapiens]
          Length = 227

 Score = 34.7 bits (78), Expect = 0.41
 Identities = 31/140 (22%), Positives = 59/140 (42%), Gaps = 7/140 (5%)

Query: 326 DSSADSENLSPDIKETTEEMEYNILVNFFKTM--GYSQEIVEKVIKVYGPSTEPLLLLE- 382
           +S   S   +P+ KE  ++M     ++   ++   +++ +   V +V G    P  +L  
Sbjct: 84  NSCHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWNEPLYHLVTEVRGMQEAPEAILSK 143

Query: 383 --EIEKENKRFQEDREFSAGTVYPETNKTKNKGVYSSTNELTTDSTPKKTQAHTQQNMVE 440
             EIE++ KR  E  E     V+PET + +   V+S    L       +  A+   N++ 
Sbjct: 144 AVEIEEQTKRLLEGMELIVSQVHPETKENEIYPVWSGLPSLQMADEESRLSAY--YNLLH 201

Query: 441 KFSQLPFKVEAKPCTSNCRI 460
              +   K++       CRI
Sbjct: 202 CLRRDSHKIDNYLKLLKCRI 221


>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 34.7 bits (78), Expect = 0.41
 Identities = 47/189 (24%), Positives = 73/189 (38%), Gaps = 37/189 (19%)

Query: 414  VYSSTNELTTDSTPKKTQAHTQQNMVEKFSQLPFKVEAKPCTSNCRINTFRTVPIEQKHE 473
            VY++T+E T+++ P K    +++N  E       +  A       R  +++   +   H 
Sbjct: 1223 VYNATSEETSNNCPVKDATASEKNEPE------VQWTASTSVEQVRERSYQRALLLSDH- 1275

Query: 474  VWGSNQNYICNTDPETDGLSPSVASPSPKEVNFVSRGASSHQPR------VPLFPENGLH 527
                        D ++ G SP V S SP  V       S+H P+      VP F E  L 
Sbjct: 1276 ----------RKDKDSGGESPCV-SCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSE--LM 1322

Query: 528  QQPEPLLPNNMKSACEKRLGCCSSPHSKPNCSTLSPPMPLPQLLPSVTDARSAG-----P 582
            + P+P  P    +        C SP +  N     P M  P    SV  A++ G     P
Sbjct: 1323 EDPDPENPEPTTT------NECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKIFTKP 1376

Query: 583  SDHIDSSVT 591
                DS+V+
Sbjct: 1377 DPQWDSTVS 1385


>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 34.7 bits (78), Expect = 0.41
 Identities = 47/189 (24%), Positives = 73/189 (38%), Gaps = 37/189 (19%)

Query: 414  VYSSTNELTTDSTPKKTQAHTQQNMVEKFSQLPFKVEAKPCTSNCRINTFRTVPIEQKHE 473
            VY++T+E T+++ P K    +++N  E       +  A       R  +++   +   H 
Sbjct: 1223 VYNATSEETSNNCPVKDATASEKNEPE------VQWTASTSVEQVRERSYQRALLLSDH- 1275

Query: 474  VWGSNQNYICNTDPETDGLSPSVASPSPKEVNFVSRGASSHQPR------VPLFPENGLH 527
                        D ++ G SP V S SP  V       S+H P+      VP F E  L 
Sbjct: 1276 ----------RKDKDSGGESPCV-SCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSE--LM 1322

Query: 528  QQPEPLLPNNMKSACEKRLGCCSSPHSKPNCSTLSPPMPLPQLLPSVTDARSAG-----P 582
            + P+P  P    +        C SP +  N     P M  P    SV  A++ G     P
Sbjct: 1323 EDPDPENPEPTTT------NECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKIFTKP 1376

Query: 583  SDHIDSSVT 591
                DS+V+
Sbjct: 1377 DPQWDSTVS 1385


>gi|19923597 Sin3A-associated protein, 130kDa isoform b [Homo
           sapiens]
          Length = 1048

 Score = 34.7 bits (78), Expect = 0.41
 Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 19/118 (16%)

Query: 482 ICNTDPETDGLSP------SVASPSPKEVNFVSRGASSHQPRVPLFPENGLHQQPEPLLP 535
           I    P TDG  P      S+A+P    +  VS   ++ QP + + P     QQP P +P
Sbjct: 670 ILRKKPATDGAKPKSEIHVSMATPVTVSMETVSN-QNNDQPTIAVPPTA---QQPPPTIP 725

Query: 536 NNMKSACEKRLGCCSSPHSKPNCSTLSPPMPLPQLLPSVTDARSAGPSDHIDSSVTGV 593
             + +A         SP S+P  +  + P  +P   P  T A +  PS  +  S++ V
Sbjct: 726 TMIAAA---------SPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSV 774


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,415,292
Number of Sequences: 37866
Number of extensions: 1782994
Number of successful extensions: 6526
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 103
Number of HSP's that attempted gapping in prelim test: 6376
Number of HSP's gapped (non-prelim): 254
length of query: 896
length of database: 18,247,518
effective HSP length: 111
effective length of query: 785
effective length of database: 14,044,392
effective search space: 11024847720
effective search space used: 11024847720
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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