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Search of human proteins with 4885503
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4885503 myosin IA [Homo sapiens]
(1043 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4885503 myosin IA [Homo sapiens] 2070 0.0
gi|44889481 myosin IB isoform 2 [Homo sapiens] 1248 0.0
gi|194328685 myosin IB isoform 1 [Homo sapiens] 1167 0.0
gi|240120050 myosin IB isoform 1 [Homo sapiens] 1167 0.0
gi|124494247 myosin IC isoform b [Homo sapiens] 789 0.0
gi|124494238 myosin IC isoform a [Homo sapiens] 789 0.0
gi|124494240 myosin IC isoform c [Homo sapiens] 789 0.0
gi|254028267 myosin 1H [Homo sapiens] 716 0.0
gi|51100974 myosin ID [Homo sapiens] 690 0.0
gi|239582755 myosin IG [Homo sapiens] 666 0.0
gi|55956916 myosin IE [Homo sapiens] 581 e-165
gi|27544941 myosin IF [Homo sapiens] 571 e-162
gi|118402590 myosin XV [Homo sapiens] 489 e-138
gi|153945715 myosin VC [Homo sapiens] 486 e-137
gi|215982794 myosin VA isoform 2 [Homo sapiens] 486 e-137
gi|215982791 myosin VA isoform 1 [Homo sapiens] 486 e-137
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 483 e-136
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 483 e-136
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 483 e-136
gi|122937345 myosin VB [Homo sapiens] 471 e-132
gi|154354979 myosin X [Homo sapiens] 469 e-132
gi|122937512 myosin VIIB [Homo sapiens] 464 e-130
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 448 e-125
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 443 e-124
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 443 e-124
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 440 e-123
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 440 e-123
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 439 e-123
gi|156104908 myosin heavy chain 6 [Homo sapiens] 439 e-123
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 434 e-121
>gi|4885503 myosin IA [Homo sapiens]
Length = 1043
Score = 2070 bits (5362), Expect = 0.0
Identities = 1043/1043 (100%), Positives = 1043/1043 (100%)
Query: 1 MPLLEGSVGVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPE 60
MPLLEGSVGVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPE
Sbjct: 1 MPLLEGSVGVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPE 60
Query: 61 FIAKYQDYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAA 120
FIAKYQDYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAA
Sbjct: 61 FIAKYQDYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAA 120
Query: 121 VCGKGEQVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITN 180
VCGKGEQVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITN
Sbjct: 121 VCGKGEQVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITN 180
Query: 181 YLLEKSRLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVDGMDD 240
YLLEKSRLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVDGMDD
Sbjct: 181 YLLEKSRLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVDGMDD 240
Query: 241 ASSFRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVR 300
ASSFRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVR
Sbjct: 241 ASSFRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVR 300
Query: 301 EIGEMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNR 360
EIGEMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNR
Sbjct: 301 EIGEMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNR 360
Query: 361 INESIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEY 420
INESIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEY
Sbjct: 361 INESIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEY 420
Query: 421 KREGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHG 480
KREGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHG
Sbjct: 421 KREGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHG 480
Query: 481 HYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQH 540
HYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQH
Sbjct: 481 HYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQH 540
Query: 541 PLLRSLFPEGNPKQASLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRGQF 600
PLLRSLFPEGNPKQASLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRGQF
Sbjct: 541 PLLRSLFPEGNPKQASLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRGQF 600
Query: 601 SSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDREGVEKV 660
SSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDREGVEKV
Sbjct: 601 SSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDREGVEKV 660
Query: 661 LGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHYQLM 720
LGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHYQLM
Sbjct: 661 LGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHYQLM 720
Query: 721 RKSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNYRKYFRSEAALTLADFIY 780
RKSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNYRKYFRSEAALTLADFIY
Sbjct: 721 RKSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNYRKYFRSEAALTLADFIY 780
Query: 781 KSMVQKFLLGLKNNLPSTNVLDKTWPAAPYKCLSTANQELQQLFYQWKCKRFRDQLSPKQ 840
KSMVQKFLLGLKNNLPSTNVLDKTWPAAPYKCLSTANQELQQLFYQWKCKRFRDQLSPKQ
Sbjct: 781 KSMVQKFLLGLKNNLPSTNVLDKTWPAAPYKCLSTANQELQQLFYQWKCKRFRDQLSPKQ 840
Query: 841 VEILREKLCASELFKGKKASYPQSVPIPFCGDYIGLQGNPKLQKLKGGEEGPVLMAEAVK 900
VEILREKLCASELFKGKKASYPQSVPIPFCGDYIGLQGNPKLQKLKGGEEGPVLMAEAVK
Sbjct: 841 VEILREKLCASELFKGKKASYPQSVPIPFCGDYIGLQGNPKLQKLKGGEEGPVLMAEAVK 900
Query: 901 KVNRGNGKTSSRILLLTKGHVILTDTKKSQAKIVIGLDNVAGVSVTSLKDGLFSLHLSEM 960
KVNRGNGKTSSRILLLTKGHVILTDTKKSQAKIVIGLDNVAGVSVTSLKDGLFSLHLSEM
Sbjct: 901 KVNRGNGKTSSRILLLTKGHVILTDTKKSQAKIVIGLDNVAGVSVTSLKDGLFSLHLSEM 960
Query: 961 SSVGSKGDFLLVSEHVIELLTKMYRAVLDATQRQLTVTVTEKFSVRFKENSVAVKVVQGP 1020
SSVGSKGDFLLVSEHVIELLTKMYRAVLDATQRQLTVTVTEKFSVRFKENSVAVKVVQGP
Sbjct: 961 SSVGSKGDFLLVSEHVIELLTKMYRAVLDATQRQLTVTVTEKFSVRFKENSVAVKVVQGP 1020
Query: 1021 AGGDNSKLRYKKKGSHCLEVTVQ 1043
AGGDNSKLRYKKKGSHCLEVTVQ
Sbjct: 1021 AGGDNSKLRYKKKGSHCLEVTVQ 1043
>gi|44889481 myosin IB isoform 2 [Homo sapiens]
Length = 1078
Score = 1248 bits (3228), Expect = 0.0
Identities = 619/1069 (57%), Positives = 801/1069 (74%), Gaps = 30/1069 (2%)
Query: 3 LLEGSVGVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFI 62
LL+ +GV D+VLLEPL EE+ + NL+ R+++ EIYTYIG+VVISVNPY+ LPIY PE +
Sbjct: 10 LLDNMIGVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKV 69
Query: 63 AKYQDYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVC 122
+Y++ FYEL PHI+AL++ AY+SLRD+D+DQCILITGESG+GKTEASKLVMSYVAAVC
Sbjct: 70 EEYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVC 129
Query: 123 GKGEQVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYL 182
GKG +VN VKEQLLQSNPVLEAFGNAKT+RN+NSSRFGKYMDIEFDFKG PLGGVI+NYL
Sbjct: 130 GKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYL 189
Query: 183 LEKSRLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVDGMDDAS 242
LEKSR+VKQ +GERNFH+FYQLL+GA E+LL LKLERD + Y YL+ + ++V+G+DDA+
Sbjct: 190 LEKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAA 249
Query: 243 SFRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREI 302
+FR V++AM ++GF + E VL V + VLKLGN+ E + +G+ S I+D ++EI
Sbjct: 250 NFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEI 309
Query: 303 GEMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRIN 362
E+ G++ +ERA RT+E +EKV T LNV QA YARDALAKN+YSRLF W+VNRIN
Sbjct: 310 CELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRIN 369
Query: 363 ESIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKR 422
ESIK +KKVMGVLDIYGFEI EDNSFEQF+INYCNEKLQQ+FIE+TLKEEQEEY R
Sbjct: 370 ESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIR 429
Query: 423 EGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHGHY 482
E I WT +DYF+N IIC LIE+N GILAMLDEECLRPG V+D TFL KLNQ+ + H H+
Sbjct: 430 EDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHF 489
Query: 483 ESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQHPL 542
ES++++ ++ D ++ SCFRI HYAGKV Y V F+DKNNDLL+RDL QAMWKA H L
Sbjct: 490 ESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHAL 549
Query: 543 LRSLFPEGNPKQASLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRGQFSS 602
++SLFPEGNP + +LKRPPTAG+QFK+SVA LMKNL +K+PNYIRCIKPN+ + F+
Sbjct: 550 IKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNE 609
Query: 603 DLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDREGVEKVLG 662
LV Q RYLGLLENVRVRRAGYA RQ Y P LERY++L + TWPHW G R GVE +
Sbjct: 610 ALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFN 669
Query: 663 ELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHYQLMRK 722
EL + E +FG++KIFIR+P+TLF LE+ R+ RL+ LATLIQKIYRGW+CRTH+ LM+K
Sbjct: 670 ELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKK 729
Query: 723 SQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARK--------------------- 761
SQI+I++W+R Q+K Y + K+S L+IQ+++RGWKARK
Sbjct: 730 SQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAY 789
Query: 762 --------NYRKYFRSEAALTLADFIYKSMVQKFLLGLKNNLPSTNVLDKTWPAAPYKCL 813
YRK+FR+ A + +F + +VQK+ L +KN +PS + +DK WP+ PY L
Sbjct: 790 WHGTQVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKMPSLSPIDKNWPSRPYLFL 849
Query: 814 STANQELQQLFYQWKCKRFRDQLSPKQVEILREKLCASELFKGKKASYPQSVPIPFCGDY 873
+ ++EL+++F+ W+CK++RDQ + +Q I EKL ASELFK KKA YP SV PF G Y
Sbjct: 850 DSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGAY 909
Query: 874 IGLQGNPKLQKLKGGEEGPVLMAEAVKKVNRGNGKTSSRILLLTKGHVILTDTKKSQAKI 933
+ + NPK +KLK E +++AE V K+NR NGK++SRI LLT +++L D K Q K
Sbjct: 910 LEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNNNLLLADQKSGQIKS 969
Query: 934 VIGLDNVAGVSVTSLKDGLFSLHLSEMSSVGSKGDFLLVSEHVIELLTKMYRAVLDATQR 993
+ L +V VS++S DG F++HL E S SKGDFL S+H+IE+ TK+YR L T++
Sbjct: 970 EVPLVDVTKVSMSSQNDGFFAVHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQ 1029
Query: 994 QLTVTVTEKFSVRFKENSVAVKVVQGPAGGDNSKLRYKKKGSHCLEVTV 1042
+L + ++++F V+F+++ V VK +QG + S K+K + LEV V
Sbjct: 1030 KLNIEISDEFLVQFRQDKVCVKFIQGNQ-KNGSVPTCKRKNNRLLEVAV 1077
>gi|194328685 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 1167 bits (3020), Expect = 0.0
Identities = 599/1127 (53%), Positives = 784/1127 (69%), Gaps = 88/1127 (7%)
Query: 3 LLEGSVGVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFI 62
LL+ +GV D+VLLEPL EE+ + NL+ R+++ EIYTYIG+VVISVNPY+ LPIY PE +
Sbjct: 10 LLDNMIGVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKV 69
Query: 63 AKYQDYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVC 122
+Y++ FYEL PHI+AL++ AY+SLRD+D+DQCILITGESG+GKTEASKLVMSYVAAVC
Sbjct: 70 EEYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVC 129
Query: 123 GKGEQVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYL 182
GKG +VN VKEQLLQSNPVLEAFGNAKT+RN+NSSRFGKYMDIEFDFKG PLGGVI+NYL
Sbjct: 130 GKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYL 189
Query: 183 LEKSRLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVDGMDDAS 242
LEKSR+VKQ +GERNFH+FYQLL+GA E+LL LKLERD + Y YL+ + ++V+G+DDA+
Sbjct: 190 LEKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAA 249
Query: 243 SFRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREI 302
+FR V++AM ++GF + E VL V + VLKLGN+ E + +G+ S I+D ++EI
Sbjct: 250 NFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEI 309
Query: 303 GEMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRIN 362
E+ G++ +ERA RT+E +EKV T LNV QA YARDALAKN+YSRLF W+VNRIN
Sbjct: 310 CELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRIN 369
Query: 363 ESIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKR 422
ESIK +KKVMGVLDIYGFEI EDNSFEQF+INYCNEKLQQ+FIE+TLKEEQEEY R
Sbjct: 370 ESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIR 429
Query: 423 EGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHGHY 482
E I WT +DYF+N IIC LIE+N GILAMLDEECLRPG V+D TFL KLNQ+ + H H+
Sbjct: 430 EDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHF 489
Query: 483 ESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQHPL 542
ES++++ ++ D ++ SCFRI HYAGKV Y V F+DKNNDLL+RDL QAMWKA H L
Sbjct: 490 ESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHAL 549
Query: 543 LRSLFPEGNPKQASLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRGQFSS 602
++SLFPEGNP + +LKRPPTAG+QFK+SVA LMKNL +K+PNYIRCIKPN+ + F+
Sbjct: 550 IKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNE 609
Query: 603 DLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDREGVEKVLG 662
LV Q RYLGLLENVRVRRAGYA RQ Y P LERY++L + TWPHW G R GVE +
Sbjct: 610 ALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFN 669
Query: 663 ELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATL------------------- 703
EL + E +FG++KIFIR+P+TLF LE+ R+ RL+ LATL
Sbjct: 670 ELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKK 729
Query: 704 ---------------------------IQKIYRGWRCRT------HYQLMRKSQILISSW 730
IQ RGW+ R H + +++ I+++
Sbjct: 730 SQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAY 789
Query: 731 FRGNMQKKCYGKIKA-----------------------------------SVLLIQAFVR 755
+ G ++ ++K +V +I A+
Sbjct: 790 WHGTQARRELRRLKEEARNKHAIAVIWAYWLGSKARRELKRLKEEARRKHAVAVIWAYWL 849
Query: 756 GWKARKNYRKYFRSEAALTLADFIYKSMVQKFLLGLKNNLPSTNVLDKTWPAAPYKCLST 815
G K R+ YRK+FR+ A + +F + +VQK+ L +KN +PS + +DK WP+ PY L +
Sbjct: 850 GLKVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKMPSLSPIDKNWPSRPYLFLDS 909
Query: 816 ANQELQQLFYQWKCKRFRDQLSPKQVEILREKLCASELFKGKKASYPQSVPIPFCGDYIG 875
++EL+++F+ W+CK++RDQ + +Q I EKL ASELFK KKA YP SV PF G Y+
Sbjct: 910 THKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGAYLE 969
Query: 876 LQGNPKLQKLKGGEEGPVLMAEAVKKVNRGNGKTSSRILLLTKGHVILTDTKKSQAKIVI 935
+ NPK +KLK E +++AE V K+NR NGK++SRI LLT +++L D K Q K +
Sbjct: 970 INKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNNNLLLADQKSGQIKSEV 1029
Query: 936 GLDNVAGVSVTSLKDGLFSLHLSEMSSVGSKGDFLLVSEHVIELLTKMYRAVLDATQRQL 995
L +V VS++S DG F++HL E S SKGDFL S+H+IE+ TK+YR L T+++L
Sbjct: 1030 PLVDVTKVSMSSQNDGFFAVHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKL 1089
Query: 996 TVTVTEKFSVRFKENSVAVKVVQGPAGGDNSKLRYKKKGSHCLEVTV 1042
+ ++++F V+F+++ V VK +QG + S K+K + LEV V
Sbjct: 1090 NIEISDEFLVQFRQDKVCVKFIQGNQ-KNGSVPTCKRKNNRLLEVAV 1135
>gi|240120050 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 1167 bits (3020), Expect = 0.0
Identities = 599/1127 (53%), Positives = 784/1127 (69%), Gaps = 88/1127 (7%)
Query: 3 LLEGSVGVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFI 62
LL+ +GV D+VLLEPL EE+ + NL+ R+++ EIYTYIG+VVISVNPY+ LPIY PE +
Sbjct: 10 LLDNMIGVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKV 69
Query: 63 AKYQDYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVC 122
+Y++ FYEL PHI+AL++ AY+SLRD+D+DQCILITGESG+GKTEASKLVMSYVAAVC
Sbjct: 70 EEYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVC 129
Query: 123 GKGEQVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYL 182
GKG +VN VKEQLLQSNPVLEAFGNAKT+RN+NSSRFGKYMDIEFDFKG PLGGVI+NYL
Sbjct: 130 GKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYL 189
Query: 183 LEKSRLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVDGMDDAS 242
LEKSR+VKQ +GERNFH+FYQLL+GA E+LL LKLERD + Y YL+ + ++V+G+DDA+
Sbjct: 190 LEKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAA 249
Query: 243 SFRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREI 302
+FR V++AM ++GF + E VL V + VLKLGN+ E + +G+ S I+D ++EI
Sbjct: 250 NFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEI 309
Query: 303 GEMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRIN 362
E+ G++ +ERA RT+E +EKV T LNV QA YARDALAKN+YSRLF W+VNRIN
Sbjct: 310 CELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRIN 369
Query: 363 ESIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKR 422
ESIK +KKVMGVLDIYGFEI EDNSFEQF+INYCNEKLQQ+FIE+TLKEEQEEY R
Sbjct: 370 ESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIR 429
Query: 423 EGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHGHY 482
E I WT +DYF+N IIC LIE+N GILAMLDEECLRPG V+D TFL KLNQ+ + H H+
Sbjct: 430 EDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHF 489
Query: 483 ESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQHPL 542
ES++++ ++ D ++ SCFRI HYAGKV Y V F+DKNNDLL+RDL QAMWKA H L
Sbjct: 490 ESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHAL 549
Query: 543 LRSLFPEGNPKQASLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRGQFSS 602
++SLFPEGNP + +LKRPPTAG+QFK+SVA LMKNL +K+PNYIRCIKPN+ + F+
Sbjct: 550 IKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNE 609
Query: 603 DLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDREGVEKVLG 662
LV Q RYLGLLENVRVRRAGYA RQ Y P LERY++L + TWPHW G R GVE +
Sbjct: 610 ALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFN 669
Query: 663 ELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATL------------------- 703
EL + E +FG++KIFIR+P+TLF LE+ R+ RL+ LATL
Sbjct: 670 ELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKK 729
Query: 704 ---------------------------IQKIYRGWRCRT------HYQLMRKSQILISSW 730
IQ RGW+ R H + +++ I+++
Sbjct: 730 SQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAY 789
Query: 731 FRGNMQKKCYGKIKA-----------------------------------SVLLIQAFVR 755
+ G ++ ++K +V +I A+
Sbjct: 790 WHGTQARRELRRLKEEARNKHAIAVIWAYWLGSKARRELKRLKEEARRKHAVAVIWAYWL 849
Query: 756 GWKARKNYRKYFRSEAALTLADFIYKSMVQKFLLGLKNNLPSTNVLDKTWPAAPYKCLST 815
G K R+ YRK+FR+ A + +F + +VQK+ L +KN +PS + +DK WP+ PY L +
Sbjct: 850 GLKVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKMPSLSPIDKNWPSRPYLFLDS 909
Query: 816 ANQELQQLFYQWKCKRFRDQLSPKQVEILREKLCASELFKGKKASYPQSVPIPFCGDYIG 875
++EL+++F+ W+CK++RDQ + +Q I EKL ASELFK KKA YP SV PF G Y+
Sbjct: 910 THKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGAYLE 969
Query: 876 LQGNPKLQKLKGGEEGPVLMAEAVKKVNRGNGKTSSRILLLTKGHVILTDTKKSQAKIVI 935
+ NPK +KLK E +++AE V K+NR NGK++SRI LLT +++L D K Q K +
Sbjct: 970 INKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNNNLLLADQKSGQIKSEV 1029
Query: 936 GLDNVAGVSVTSLKDGLFSLHLSEMSSVGSKGDFLLVSEHVIELLTKMYRAVLDATQRQL 995
L +V VS++S DG F++HL E S SKGDFL S+H+IE+ TK+YR L T+++L
Sbjct: 1030 PLVDVTKVSMSSQNDGFFAVHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKL 1089
Query: 996 TVTVTEKFSVRFKENSVAVKVVQGPAGGDNSKLRYKKKGSHCLEVTV 1042
+ ++++F V+F+++ V VK +QG + S K+K + LEV V
Sbjct: 1090 NIEISDEFLVQFRQDKVCVKFIQGNQ-KNGSVPTCKRKNNRLLEVAV 1135
>gi|124494247 myosin IC isoform b [Homo sapiens]
Length = 1044
Score = 789 bits (2037), Expect = 0.0
Identities = 434/983 (44%), Positives = 624/983 (63%), Gaps = 31/983 (3%)
Query: 8 VGVEDLVLLEPLVEES-LLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQ 66
VGV+D VLLE E+ ++NL+ R+ IYTYIG V++SVNPY+ L IY + + +Y+
Sbjct: 27 VGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYR 86
Query: 67 DYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGE 126
+FYE+ PH++A+A+ Y++LR RDQ ++I+GESG+GKTEA+K ++ + A C E
Sbjct: 87 GVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPE 146
Query: 127 QVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKS 186
+ +V+++LLQSNPVLEAFGNAKT+RN+NSSRFGKYMD++FDFKG+P+GG I +YLLEKS
Sbjct: 147 RGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKS 206
Query: 187 RLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYL-NHEVSRVDGMDDASSFR 245
R+V Q GERNFHIFYQLL G +E+ L+ L LER+ Y YL + ++V ++D S ++
Sbjct: 207 RVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWK 266
Query: 246 AVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIGEM 305
V+ A+ VI F+E+E+ +L + + VL LGN+ F A+ + + ++ + +
Sbjct: 267 VVRKALTVIDFTEDEVEDLLSIVASVLHLGNI----HFAANEESNAQVTTENQLKYLTRL 322
Query: 306 VGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINESI 365
+ + + AL R + E++++ LN+ QA YARDALAK +YSR F W+V +IN S+
Sbjct: 323 LSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL 382
Query: 366 KVGIGEKKK-----VMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEY 420
E V+G+LDIYGFE+ + NSFEQF INYCNEKLQQ+FIE+TLK EQEEY
Sbjct: 383 ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEY 442
Query: 421 KREGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHG 480
+ EGI W V YF+N IIC L+E +GI+++LDEECLRPG +D TFL KL H
Sbjct: 443 EAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHP 502
Query: 481 HYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQH 540
H+ + + A ++ ++G FR+ HYAG+VTY+VT F+DKNNDLLFR+L + M +++
Sbjct: 503 HFLTH--KLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKN 560
Query: 541 PLLRSLFPEGNPKQASLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRGQF 600
P++ F + + KRP T QFK S+ L++ L SK P Y+RCIKPN+ +Q G+F
Sbjct: 561 PIMSQCFDRS--ELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRF 618
Query: 601 SSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDREGVEKV 660
L+ Q +YLGLLEN+RVRRAG+A+R+ Y FL+RY+ L TWP W G ++GV +
Sbjct: 619 DEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVL 678
Query: 661 LGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHYQLM 720
+ L E G+TKIFIR PKTLF E+ +R Q LAT IQ +RG+ R + +
Sbjct: 679 VRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRV 738
Query: 721 RKSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNYRKYFRSEAALTLADFIY 780
++S I I SW+RG + ++ K K + I+ +RG+ R R + F
Sbjct: 739 KRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENA--------FFL 790
Query: 781 KSMVQKFLLGLKNNLPSTNVLDKTWPAAPYKCLSTANQELQQLFYQWKCKRFRDQLSPKQ 840
+ FLL L+ LP NVLD +WP P L A++ L++L + ++ +SP+
Sbjct: 791 DHVRTSFLLNLRRQLPQ-NVLDTSWPTPP-PALREASELLRELCIKNMVWKYCRSISPEW 848
Query: 841 VEILREKLCASELFKGKKASYPQSVPIPFCGDYIGL-QGNPKLQKLKGGEEGPVLMAEAV 899
+ L++K ASE+FKGKK +YPQSVP F +G + +P++ + G E P+ A V
Sbjct: 849 KQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQALGSE--PIQYAVPV 906
Query: 900 KKVNRGNGKTSSRILLLTKGHVILTDTKKSQAKIVIGLDNVAGVSVTSLKDGLFSLHLSE 959
K +R K SR LLLT V++ + K + + I N+ G+SV+SL D LF LH+
Sbjct: 907 VKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQR--IDYANLTGISVSSLSDSLFVLHVQR 964
Query: 960 MSSVGSKGDFLLVSEHVIELLTK 982
+ KGD +L S+HVIE LTK
Sbjct: 965 ADN-KQKGDVVLQSDHVIETLTK 986
>gi|124494238 myosin IC isoform a [Homo sapiens]
Length = 1063
Score = 789 bits (2037), Expect = 0.0
Identities = 434/983 (44%), Positives = 624/983 (63%), Gaps = 31/983 (3%)
Query: 8 VGVEDLVLLEPLVEES-LLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQ 66
VGV+D VLLE E+ ++NL+ R+ IYTYIG V++SVNPY+ L IY + + +Y+
Sbjct: 46 VGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYR 105
Query: 67 DYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGE 126
+FYE+ PH++A+A+ Y++LR RDQ ++I+GESG+GKTEA+K ++ + A C E
Sbjct: 106 GVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPE 165
Query: 127 QVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKS 186
+ +V+++LLQSNPVLEAFGNAKT+RN+NSSRFGKYMD++FDFKG+P+GG I +YLLEKS
Sbjct: 166 RGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKS 225
Query: 187 RLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYL-NHEVSRVDGMDDASSFR 245
R+V Q GERNFHIFYQLL G +E+ L+ L LER+ Y YL + ++V ++D S ++
Sbjct: 226 RVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWK 285
Query: 246 AVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIGEM 305
V+ A+ VI F+E+E+ +L + + VL LGN+ F A+ + + ++ + +
Sbjct: 286 VVRKALTVIDFTEDEVEDLLSIVASVLHLGNI----HFAANEESNAQVTTENQLKYLTRL 341
Query: 306 VGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINESI 365
+ + + AL R + E++++ LN+ QA YARDALAK +YSR F W+V +IN S+
Sbjct: 342 LSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL 401
Query: 366 KVGIGEKKK-----VMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEY 420
E V+G+LDIYGFE+ + NSFEQF INYCNEKLQQ+FIE+TLK EQEEY
Sbjct: 402 ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEY 461
Query: 421 KREGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHG 480
+ EGI W V YF+N IIC L+E +GI+++LDEECLRPG +D TFL KL H
Sbjct: 462 EAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHP 521
Query: 481 HYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQH 540
H+ + + A ++ ++G FR+ HYAG+VTY+VT F+DKNNDLLFR+L + M +++
Sbjct: 522 HFLTH--KLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKN 579
Query: 541 PLLRSLFPEGNPKQASLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRGQF 600
P++ F + + KRP T QFK S+ L++ L SK P Y+RCIKPN+ +Q G+F
Sbjct: 580 PIMSQCFDRS--ELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRF 637
Query: 601 SSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDREGVEKV 660
L+ Q +YLGLLEN+RVRRAG+A+R+ Y FL+RY+ L TWP W G ++GV +
Sbjct: 638 DEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVL 697
Query: 661 LGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHYQLM 720
+ L E G+TKIFIR PKTLF E+ +R Q LAT IQ +RG+ R + +
Sbjct: 698 VRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRV 757
Query: 721 RKSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNYRKYFRSEAALTLADFIY 780
++S I I SW+RG + ++ K K + I+ +RG+ R R + F
Sbjct: 758 KRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENA--------FFL 809
Query: 781 KSMVQKFLLGLKNNLPSTNVLDKTWPAAPYKCLSTANQELQQLFYQWKCKRFRDQLSPKQ 840
+ FLL L+ LP NVLD +WP P L A++ L++L + ++ +SP+
Sbjct: 810 DHVRTSFLLNLRRQLPQ-NVLDTSWPTPP-PALREASELLRELCIKNMVWKYCRSISPEW 867
Query: 841 VEILREKLCASELFKGKKASYPQSVPIPFCGDYIGL-QGNPKLQKLKGGEEGPVLMAEAV 899
+ L++K ASE+FKGKK +YPQSVP F +G + +P++ + G E P+ A V
Sbjct: 868 KQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQALGSE--PIQYAVPV 925
Query: 900 KKVNRGNGKTSSRILLLTKGHVILTDTKKSQAKIVIGLDNVAGVSVTSLKDGLFSLHLSE 959
K +R K SR LLLT V++ + K + + I N+ G+SV+SL D LF LH+
Sbjct: 926 VKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQR--IDYANLTGISVSSLSDSLFVLHVQR 983
Query: 960 MSSVGSKGDFLLVSEHVIELLTK 982
+ KGD +L S+HVIE LTK
Sbjct: 984 ADN-KQKGDVVLQSDHVIETLTK 1005
>gi|124494240 myosin IC isoform c [Homo sapiens]
Length = 1028
Score = 789 bits (2037), Expect = 0.0
Identities = 434/983 (44%), Positives = 624/983 (63%), Gaps = 31/983 (3%)
Query: 8 VGVEDLVLLEPLVEES-LLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQ 66
VGV+D VLLE E+ ++NL+ R+ IYTYIG V++SVNPY+ L IY + + +Y+
Sbjct: 11 VGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYR 70
Query: 67 DYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGE 126
+FYE+ PH++A+A+ Y++LR RDQ ++I+GESG+GKTEA+K ++ + A C E
Sbjct: 71 GVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPE 130
Query: 127 QVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKS 186
+ +V+++LLQSNPVLEAFGNAKT+RN+NSSRFGKYMD++FDFKG+P+GG I +YLLEKS
Sbjct: 131 RGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKS 190
Query: 187 RLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYL-NHEVSRVDGMDDASSFR 245
R+V Q GERNFHIFYQLL G +E+ L+ L LER+ Y YL + ++V ++D S ++
Sbjct: 191 RVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWK 250
Query: 246 AVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIGEM 305
V+ A+ VI F+E+E+ +L + + VL LGN+ F A+ + + ++ + +
Sbjct: 251 VVRKALTVIDFTEDEVEDLLSIVASVLHLGNI----HFAANEESNAQVTTENQLKYLTRL 306
Query: 306 VGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINESI 365
+ + + AL R + E++++ LN+ QA YARDALAK +YSR F W+V +IN S+
Sbjct: 307 LSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL 366
Query: 366 KVGIGEKKK-----VMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEY 420
E V+G+LDIYGFE+ + NSFEQF INYCNEKLQQ+FIE+TLK EQEEY
Sbjct: 367 ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEY 426
Query: 421 KREGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHG 480
+ EGI W V YF+N IIC L+E +GI+++LDEECLRPG +D TFL KL H
Sbjct: 427 EAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHP 486
Query: 481 HYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQH 540
H+ + + A ++ ++G FR+ HYAG+VTY+VT F+DKNNDLLFR+L + M +++
Sbjct: 487 HFLTH--KLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKN 544
Query: 541 PLLRSLFPEGNPKQASLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRGQF 600
P++ F + + KRP T QFK S+ L++ L SK P Y+RCIKPN+ +Q G+F
Sbjct: 545 PIMSQCFDRS--ELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRF 602
Query: 601 SSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDREGVEKV 660
L+ Q +YLGLLEN+RVRRAG+A+R+ Y FL+RY+ L TWP W G ++GV +
Sbjct: 603 DEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVL 662
Query: 661 LGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHYQLM 720
+ L E G+TKIFIR PKTLF E+ +R Q LAT IQ +RG+ R + +
Sbjct: 663 VRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRV 722
Query: 721 RKSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNYRKYFRSEAALTLADFIY 780
++S I I SW+RG + ++ K K + I+ +RG+ R R + F
Sbjct: 723 KRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENA--------FFL 774
Query: 781 KSMVQKFLLGLKNNLPSTNVLDKTWPAAPYKCLSTANQELQQLFYQWKCKRFRDQLSPKQ 840
+ FLL L+ LP NVLD +WP P L A++ L++L + ++ +SP+
Sbjct: 775 DHVRTSFLLNLRRQLPQ-NVLDTSWPTPP-PALREASELLRELCIKNMVWKYCRSISPEW 832
Query: 841 VEILREKLCASELFKGKKASYPQSVPIPFCGDYIGL-QGNPKLQKLKGGEEGPVLMAEAV 899
+ L++K ASE+FKGKK +YPQSVP F +G + +P++ + G E P+ A V
Sbjct: 833 KQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQALGSE--PIQYAVPV 890
Query: 900 KKVNRGNGKTSSRILLLTKGHVILTDTKKSQAKIVIGLDNVAGVSVTSLKDGLFSLHLSE 959
K +R K SR LLLT V++ + K + + I N+ G+SV+SL D LF LH+
Sbjct: 891 VKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQR--IDYANLTGISVSSLSDSLFVLHVQR 948
Query: 960 MSSVGSKGDFLLVSEHVIELLTK 982
+ KGD +L S+HVIE LTK
Sbjct: 949 ADN-KQKGDVVLQSDHVIETLTK 970
>gi|254028267 myosin 1H [Homo sapiens]
Length = 1022
Score = 716 bits (1848), Expect = 0.0
Identities = 401/984 (40%), Positives = 607/984 (61%), Gaps = 28/984 (2%)
Query: 8 VGVEDLVLLEPLVEES-LLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQ 66
VGV+D VLL+ ES + NL+ R+ IYTYIG +++SVNPYQ+L IY + YQ
Sbjct: 11 VGVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQ 70
Query: 67 DYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGE 126
F+EL PH+YA+A+ AY+ + + ILI+GESG+GKTEASK ++ Y A C +
Sbjct: 71 GVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQ 130
Query: 127 QVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKS 186
+ +++LL SNPVLEAFGNA+T+RN+NSSRFGKYMDI+FDF+G P+GG I +YL+EKS
Sbjct: 131 SLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKS 190
Query: 187 RLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNH-EVSRVDGMDDASSFR 245
R+V Q +GERNFHIFYQLLAG +E+ L L LERD Y YL+ ++ + D + ++
Sbjct: 191 RVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWK 250
Query: 246 AVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIGEM 305
V +A +VI F+E ++ + + + VL LGN+ ++ Q + I D ++ I ++
Sbjct: 251 TVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQG----CATIPDTHEIKWIAKL 306
Query: 306 VGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINESI 365
+G++ + AL R +E E+V+ L + + YARDA+AK +Y R F W+VN+IN S+
Sbjct: 307 LGVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSL 366
Query: 366 KVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKREGI 425
+K V+G+LDIYGFE+ + N FEQF INYCNEKLQQ+ IE TLK EQ EY+ EGI
Sbjct: 367 VNKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGI 426
Query: 426 PWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHGHYESK 485
W + YF+N IIC L+E +GI+++LDEEC+RPG +D +FL KL + KH H+E++
Sbjct: 427 EWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETR 486
Query: 486 VTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQHPLLRS 545
+ + +G FR+ HYAG+VTY F++KNNDLL+R L + + K+++ +LR
Sbjct: 487 KLAGPKGR--KRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRE 544
Query: 546 LFPEGNPKQASLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRGQFSSDLV 605
F + + +RPPT G QFK+S++ L++ L SK P+YIRCIKPN+ ++ +F L+
Sbjct: 545 CFLLA--ELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDFLI 602
Query: 606 ATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDREGVEKVLGELS 665
Q +YLGL+E++RVRRAG+A+R+ Y FL+RY+ L TWPHW+G EGVE+++ +
Sbjct: 603 RHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVERLIKYIG 662
Query: 666 MSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHYQLMRKSQI 725
E GKTKIFIR P+TLF E+ QL IQ Y+ R Y R++ I
Sbjct: 663 YKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYVKKRQAAI 722
Query: 726 LISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNYRKYFRSEAALTLADFIYKSMVQ 785
+ + +RG + +K + K +V +I+ F++G+ +R E + F+ K+
Sbjct: 723 KLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEFIV----FVRKN--- 775
Query: 786 KFLLGLKNNLPSTNVLDKTWPAAPYKCLSTANQELQQLFYQWKCKRFRDQLSPKQVEILR 845
++L L+ +LP T VLDK+W P L A+ L+++ + +++ ++ ++ +++
Sbjct: 776 -YILNLRYHLPKT-VLDKSW-LRPPGILENASDLLRKMCVRNLVQKYCRGITAERKAMMQ 832
Query: 846 EKLCASELFKGKKASYPQSVPIPFCGDYIGLQG--NPKLQKLKGGEEGPVLMAEAVKKVN 903
+K+ SE+F+G+K Y +S+ PF I +G NPK+ +L E+ + V K +
Sbjct: 833 QKVVTSEIFRGRKDGYTESLNQPFVNSRID-EGDINPKVLQLISHEK--IQYGVPVIKYD 889
Query: 904 RGNGKTSSRILLLTKGHVILTDTKKSQAKIVIGLDNVAGVSVTSLKDGLFSLHLSEMSSV 963
R K R L+LT+ + + K + KI + GVS ++L DG+ +H+S S
Sbjct: 890 RKGFKARQRQLILTQKAAYVVELAKIKQKIEYSA--LKGVSTSNLSDGILVIHVSPEDS- 946
Query: 964 GSKGDFLLVSEHVIELLTKMYRAV 987
KGD +L HV E +TK+ V
Sbjct: 947 KQKGDAVLQCGHVFEAVTKLVMLV 970
>gi|51100974 myosin ID [Homo sapiens]
Length = 1006
Score = 690 bits (1780), Expect = 0.0
Identities = 400/973 (41%), Positives = 575/973 (59%), Gaps = 81/973 (8%)
Query: 9 GVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDY 68
G D VL++ + + NL+LR+E IYT+IG VV+SVNPY+ L IYG + I +Y+
Sbjct: 10 GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69
Query: 69 TFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGE-- 126
YE PH++A+A+ AY++++ R +D CI+I+GESG+GKTEASK +M Y+AA+ +
Sbjct: 70 ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129
Query: 127 QVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKS 186
+V VK LL+SN VLEAFGNAKT RN+NSSRFGKYMDI FDFKG P+GG I NYLLEKS
Sbjct: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189
Query: 187 RLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVDGMDDASSFRA 246
R++ Q GER+FH FYQLL G EQ+L++L L++ + Y Y++ ++DA+ FR
Sbjct: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFRV 249
Query: 247 VQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIGEMV 306
V AM VIGF EEI+ V ++ + +L LGN+ +F G I +G+ V I E++
Sbjct: 250 VADAMKVIGFKPEEIQTVYKILAAILHLGNL----KFVVDG-DTPLIENGKVVSIIAELL 304
Query: 307 GLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINESIK 366
++ VE+AL RT+ T ++ + +A Y RDA AK IY RLF WIV RIN+ I+
Sbjct: 305 STKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIE 364
Query: 367 V-----GIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYK 421
V I K V+GVLDIYGFEI ++NSFEQF INYCNEKLQQ+FI++ LK+EQEEY+
Sbjct: 365 VKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQ 424
Query: 422 REGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHGH 481
REGIPW +DYF+N II L+E +GI+A+LD+ C+ G V+D FL LN KH H
Sbjct: 425 REGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAH 484
Query: 482 YESKVTQNAQR--QYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQ 539
+ S+ + + ++D FRI HYAG V Y+V FIDKN D LF+D + M+ +
Sbjct: 485 FSSRKLCASDKILEFDRD-----FRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSS 539
Query: 540 HPLLRSLFPEGNPKQASL-KRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRG 598
+P+L++++PEG + KRP TA FK+S+ L+ NL SK P Y+RCIKPN+ +
Sbjct: 540 NPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQ 599
Query: 599 QFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWP-HWNGGDREGV 657
F + Q YLGLLENVRVRRAG+A RQ Y FL RY+++S TWP H D+E V
Sbjct: 600 IFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAV 659
Query: 658 EKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHY 717
+K++ ++A+GKTKIFIR+P+TLF LEE R L ++ +QK++RG R Y
Sbjct: 660 KKLIERCGFQD-DVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRY 718
Query: 718 QLMRKSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNYRKYFRSEAALTLAD 777
+ + + +I + R K+K+ + + G K ++Y K+ +
Sbjct: 719 KRTKAALTIIRYYRR--------YKVKSYIHEVARRFHGVKTMRDYGKHVK--------- 761
Query: 778 FIYKSMVQKFLLGLKNNLPSTNVLDKTWPAAPYKCLSTANQELQQLFYQWKCKRFRDQLS 837
WP+ P K L + LQ +F +W+ + +
Sbjct: 762 ---------------------------WPSPP-KVLRRFEEALQTIFNRWRASQLIKSIP 793
Query: 838 PKQVEILREKLCASELFKGKKASYPQSVPIPFCGDYIGLQGN---------PKLQKLKGG 888
+ +R K+ A E+ KG++A + + G+Y+ + + P +LK
Sbjct: 794 ASDLPQVRAKVAAVEMLKGQRADL--GLQRAWEGNYLASKPDTPQTSGTFVPVANELKRK 851
Query: 889 EE-GPVLMAEAVKKVNRGNGKTSSRILLLTKGHVILTD-TKKSQAKIVIGLDNVAGVSVT 946
++ VL + V+KVNR + K R + +T H+ D TK+ + I L N+ G+SV+
Sbjct: 852 DKYMNVLFSCHVRKVNRFS-KVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVS 910
Query: 947 SLKDGLFSLHLSE 959
+ KD L H +
Sbjct: 911 NGKDQLVVFHTKD 923
>gi|239582755 myosin IG [Homo sapiens]
Length = 1018
Score = 666 bits (1718), Expect = 0.0
Identities = 418/987 (42%), Positives = 567/987 (57%), Gaps = 103/987 (10%)
Query: 9 GVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDY 68
G D VLL+ + E ++NLQLR+E IYTYIG V++SVNPYQ+LP+YGPE IA+YQ
Sbjct: 10 GKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIARYQGR 69
Query: 69 TFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGE-- 126
YE PH+YA+AN AY++++ R RD CI+I+GESG+GKTEASK +M Y+AAV +
Sbjct: 70 ELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQRA 129
Query: 127 QVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKS 186
+V VK+ LL+S VLEAFGNA+T RN+NSSRFGKYMDI FDFKG P+GG I +YLLEKS
Sbjct: 130 EVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEKS 189
Query: 187 RLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGY------AYLNHEV-SRVDGMD 239
R++KQ GERNFH FYQLL G++++ L L LER+ Y A LN V S +D
Sbjct: 190 RVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALD--S 247
Query: 240 DASSFRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASG--IRDGR 297
D S +AV AM VIGFS EE+ V + + +L LGN+ E + G+ G + +
Sbjct: 248 DEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFV-ETEEGGLQKEGLAVAEEA 306
Query: 298 GVREIGEMVGLNSEEVERALCSRTMET-AKEKVVTALNVMQAQYARDALAKNIYSRLFDW 356
V + E+ + V R+L +RT+ + +E + +A YARDA AK +Y RLF+W
Sbjct: 307 LVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQRLFEW 366
Query: 357 IVNRINESIKVGIGE------KKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIE 410
+VNRIN S+ G K V+GVLDIYGFE+ NSFEQF INYCNEKLQQ+FI+
Sbjct: 367 VVNRIN-SVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQ 425
Query: 411 MTLKEEQEEYKREGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLA 470
+ LK+EQEEY+REGI W V+YF+N I L+E RGILA+LDE C G ++D FL
Sbjct: 426 LILKQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDRIFLQ 485
Query: 471 KLNQLFSKHGHYESKVTQNAQRQYDHTMGLS-CFRICHYAGKVTYNVTSFIDKNNDLLFR 529
L+ H HY S+ D TM FRI HYAG VTY+V FIDKN D LF+
Sbjct: 486 TLDMHHRHHLHYTSRQLCPT----DKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLFQ 541
Query: 530 DLLQAMWKAQHPLLRSLFPEGNPKQASL-KRPPTAGAQFKSSVAILMKNLYSKSPNYIRC 588
D + ++ + P LR+++P+G + KRP TAG FK+S+ L++NL SK P Y+RC
Sbjct: 542 DFKRLLYNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVRC 601
Query: 589 IKPNEHQQRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWP- 647
IKPNE + G+ + Q YLGLLENVRVRRAG+A RQ Y FL RY++ TWP
Sbjct: 602 IKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWPN 661
Query: 648 HWNGGDREGVEKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKI 707
H G D+ V +L + + G++AFG +K+FIRSP+TL LE+ R + + L+QK
Sbjct: 662 HLLGSDKAAVSALLEQHGL-QGDVAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQKA 720
Query: 708 YRG----WRC---RTHYQLMRKSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKAR 760
+RG WRC R Y +MR WFR + K++A + +Q R ++A
Sbjct: 721 WRGTLARWRCRRLRAIYTIMR--------WFRRH-------KVRAHLAELQ---RRFQAA 762
Query: 761 KNYRKYFRSEAALTLADFIYKSMVQKFLLGLKNNLPSTNVLDKTWPAAPYKCLSTANQEL 820
+ Y R D WP P L
Sbjct: 763 RQPPLYGR---------------------------------DLVWPLPP-AVLQPFQDTC 788
Query: 821 QQLFYQWKCKRFRDQLSPKQVEILREKLCASELFKGKKASYPQSVPIPFCGDYI-GLQGN 879
LF +W+ ++ + P + ++ K+ A +G + + + DY+ N
Sbjct: 789 HALFCRWRARQLVKNIPPSDMPQIKAKVAAMGALQGLRQDW--GCRRAWARDYLSSATDN 846
Query: 880 PK-----LQKLKGGEE----GPVLMAEAVKKVNRGNGKTSSRILLLTKGHVILTD-TKKS 929
P Q+LK ++ G VL + V+KVNR + K +R LLLT H+ D ++
Sbjct: 847 PTASSLFAQRLKTLQDKDGFGAVLFSSHVRKVNRFH-KIRNRALLLTDQHLYKLDPDRQY 905
Query: 930 QAKIVIGLDNVAGVSVTSLKDGLFSLH 956
+ + L+ V G+SVTS D L LH
Sbjct: 906 RVMRAVPLEAVTGLSVTSGGDQLVVLH 932
>gi|55956916 myosin IE [Homo sapiens]
Length = 1108
Score = 581 bits (1497), Expect = e-165
Identities = 321/724 (44%), Positives = 465/724 (64%), Gaps = 33/724 (4%)
Query: 9 GVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDY 68
GV+D+VLL + E S+++NL+ RY + I+TYIG+V+ISVNP++Q+P +G + I YQ
Sbjct: 20 GVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGA 79
Query: 69 TFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGEQV 128
YE PHIYALA+ Y+++ +QC++I+GESG+GKT A+K +MSY++ V G G +V
Sbjct: 80 AQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTKV 139
Query: 129 NSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKSRL 188
VK+ +LQSNP+LEAFGNAKT+RNNNSSRFGKY +I+F G P GG I+N+LLEKSR+
Sbjct: 140 QHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRV 199
Query: 189 VKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVS-RVDGMDDASSFRAV 247
V + GER+FHIFYQL+ GA + +L + Y YL+ S +VD +DD F+
Sbjct: 200 VMRNPGERSFHIFYQLIEGASAEQKHSLGI-TSMDYYYYLSLSGSYKVDDIDDRREFQET 258
Query: 248 QSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIGEMVG 307
AM VIG EE VL++ + +L LGN+ F+ G A+ + + ++G
Sbjct: 259 LHAMNVIGIFAEEQTLVLQIVAGILHLGNI----SFKEVGNYAA-VESEEFLAFPAYLLG 313
Query: 308 LNSEEVERALCSRTMET----AKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINE 363
+N + ++ L SR M++ E + LNV QA Y RDALAK +++R+FD++V+ IN+
Sbjct: 314 INQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINK 373
Query: 364 SIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKRE 423
+++ E +GVLDIYGFEI + N FEQF IN+ NEKLQQ+FIE+TLK EQEEY +E
Sbjct: 374 AMEKDHEEYN--IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQE 431
Query: 424 GIPWTKVDYFDNGIICKLIEH--NQRGILAMLDEECLRPGVV---SDSTFLAKLNQLFSK 478
GI WT ++YF+N I+C LIE+ N GI+++LD+ C V +D T L KL
Sbjct: 432 GIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGS 491
Query: 479 HGHYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKA 538
H H+ S G F I HYAGKV+Y++ F ++N D+LF DL++ M +
Sbjct: 492 HEHFNS-----------WNQG---FIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSS 537
Query: 539 QHPLLRSLFPEGNPKQASLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRG 598
+ P ++SLFPE N + RP TAG++ K L+ L +P+YIRCIKPNE ++
Sbjct: 538 ELPFIKSLFPE-NLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPR 596
Query: 599 QFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDREGVE 658
+ V Q YLGL EN+RVRRAGYA+R+ + FL+RY +L+++TWP W G +++GV
Sbjct: 597 DWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVL 656
Query: 659 KVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHYQ 718
+L ++M S + G++K+FI++P++LF LEE R + A +IQK +R + R Y
Sbjct: 657 HLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYV 716
Query: 719 LMRK 722
MR+
Sbjct: 717 QMRE 720
Score = 59.3 bits (142), Expect = 2e-08
Identities = 54/193 (27%), Positives = 93/193 (48%), Gaps = 22/193 (11%)
Query: 830 KRFRDQLSPKQVEILREKLCASELFKGKKASYPQSVPIPFCGDYIGLQGNPKLQKLKGGE 889
K +R ++ K+ +RE+ AS+L KK S+ F GDYIG++ +P+LQ+ G
Sbjct: 704 KSWRKFVARKKYVQMREE--ASDLLLNKKERRRNSINRNFIGDYIGMEEHPELQQFVGKR 761
Query: 890 EGPVLMAEAVKKVNRGNGKTSSRILLLTKGHVILTDTKKSQ-----------AKIVIGLD 938
E + A+ V K +R K R LLLT + L +K + K I ++
Sbjct: 762 E-KIDFADTVTKYDR-RFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIE 819
Query: 939 NVAGVSVTSLKDGLFSLHLSEMSSVGSKGDFLLVSEHVIELLTKMYRAVLDATQRQLTVT 998
+ VS+++++D +F LH E D LL S E L+ + + + TQ+QL +
Sbjct: 820 RILSVSLSTMQDDIFILHEQEY-------DSLLESVFKTEFLSLLAKRYEEKTQKQLPLK 872
Query: 999 VTEKFSVRFKENS 1011
+ ++ K+ +
Sbjct: 873 FSNTLELKLKKEN 885
>gi|27544941 myosin IF [Homo sapiens]
Length = 1098
Score = 571 bits (1472), Expect = e-162
Identities = 318/735 (43%), Positives = 462/735 (62%), Gaps = 41/735 (5%)
Query: 9 GVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDY 68
GV+D+VLL + E+++ NL+ R+ + I+TYIG+V+ISVNP++Q+P + I YQ
Sbjct: 18 GVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGA 77
Query: 69 TFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGEQV 128
YE PHIYAL + Y+++ +QC++I+GESG+GKT A+K +M Y++ V G GE+V
Sbjct: 78 AQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEKV 137
Query: 129 NSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKSRL 188
VK+ +LQSNP+LEAFGNAKT+RNNNSSRFGKY +I+F G P GG I+N+LLEKSR+
Sbjct: 138 QHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRV 197
Query: 189 VKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNH-EVSRVDGMDDASSFRAV 247
V Q + ERNFHI+YQLL GA ++ + L L Y YLN + +VDG DD S F
Sbjct: 198 VMQNENERNFHIYYQLLEGASQEQRQNLGL-MTPDYYYYLNQSDTYQVDGTDDRSDFGET 256
Query: 248 QSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIGEMVG 307
SAM VIG + VL++ + +L LGN+ ++ + + + + + ++G
Sbjct: 257 LSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDL-----LAFPAYLLG 311
Query: 308 LNSEEVERALCSRTMET----AKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINE 363
++S ++ L SR M++ E + LNV QA Y RDALAK +Y+RLFD++V IN
Sbjct: 312 IDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINR 371
Query: 364 SIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKRE 423
+++ +++ +GVLDIYGFEI + N FEQF IN+ NEKLQQ+FIE+TLK EQEEY +E
Sbjct: 372 AMQK--PQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQE 429
Query: 424 GIPWTKVDYFDNGIICKLIEH--NQRGILAMLDEECL---RPGVVSDSTFLAKLNQLFSK 478
GI WT + YF+N ++C LIE+ + GI+++LD+ C G +D T L KL
Sbjct: 430 GIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGT 489
Query: 479 HGHYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKA 538
H H+ S + F I HYAGKV+Y+V+ F ++N D+LF DL++ M +
Sbjct: 490 HEHFNS--------------WSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTS 535
Query: 539 QHPLLRSLFPE---GNPKQASLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQ 595
+ LR LFPE G+ K RP TAG++ K L+ L +P+YIRCIKPNE +
Sbjct: 536 EQAFLRMLFPEKLDGDKK----GRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETK 591
Query: 596 QRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDRE 655
+ + + V Q YLGL EN+RVRRAG+A+R+ + FL+RY +L+ TWP W G +R+
Sbjct: 592 RPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQ 651
Query: 656 GVEKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRT 715
GV+ +L ++M + G TK+F+++P++LF LEE R + A IQK +R
Sbjct: 652 GVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVR 711
Query: 716 HYQLMRK--SQILIS 728
Y+ MR+ S IL++
Sbjct: 712 KYEEMREEASNILLN 726
Score = 50.4 bits (119), Expect = 8e-06
Identities = 50/191 (26%), Positives = 88/191 (46%), Gaps = 22/191 (11%)
Query: 830 KRFRDQLSPKQVEILREKLCASELFKGKKASYPQSVPIPFCGDYIGLQGNPKLQKLKGGE 889
K +R ++ ++ E +RE+ AS + KK S+ F GDY+GL+ P+L++ G
Sbjct: 702 KAWRRHVAVRKYEEMREE--ASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKR 759
Query: 890 EGPVLMAEAVKKVNRGNGKTSSRILLLTKGHVILTDTKKSQ-----------AKIVIGLD 938
E V A++V K +R K R L+LT V + +K + K + +
Sbjct: 760 E-RVDFADSVTKYDR-RFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQ 817
Query: 939 NVAGVSVTSLKDGLFSLHLSEMSSVGSKGDFLLVSEHVIELLTKMYRAVLDATQRQLTVT 998
+ GVS+++ +D F L D L S E ++ + + +AT+R L +T
Sbjct: 818 ALRGVSLSTRQDDFFILQ-------EDAADSFLESVFKTEFVSLLCKRFEEATRRPLPLT 870
Query: 999 VTEKFSVRFKE 1009
++ R K+
Sbjct: 871 FSDTLQFRVKK 881
>gi|118402590 myosin XV [Homo sapiens]
Length = 3530
Score = 489 bits (1260), Expect = e-138
Identities = 292/775 (37%), Positives = 453/775 (58%), Gaps = 39/775 (5%)
Query: 6 GSVGVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKY 65
G GVED+ LE L E ++L NL++R+E IYTYIG++++SVNPYQ IYGPE + +Y
Sbjct: 1220 GEDGVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQY 1279
Query: 66 QDYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKG 125
E PH++A+AN+A+ + D ++QCI+I+GESGSGKTEA+KL++ Y+AA+ K
Sbjct: 1280 NGRALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKR 1339
Query: 126 EQVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITN-YLLE 184
E + +K +L++ P+LE+FGNAKT+RN+NSSRFGK+ +E +G + G IT+ YLLE
Sbjct: 1340 EVMQQIK--ILEATPLLESFGNAKTVRNDNSSRFGKF--VEIFLEGGVISGAITSQYLLE 1395
Query: 185 KSRLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVS-RVDGMDDASS 243
KSR+V Q K ERN+HIFY+LLAG QL +A L+ T Y YLN + + G DA
Sbjct: 1396 KSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAET-YYYLNQGGNCEIAGKSDADD 1454
Query: 244 FRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIG 303
FR + +AM V+GFS E+ + + + +L LGNV ++++ + + R ++ +
Sbjct: 1455 FRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYF-EKYETDAQEVASVVSAREIQAVA 1513
Query: 304 EMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINE 363
E++ ++ E +++A+ + ET +EK+ T L V A ARDA+AK +Y+ LF W++ R+N
Sbjct: 1514 ELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVN- 1572
Query: 364 SIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKRE 423
V + + +LDIYGFE L NSFEQ INY NE LQ +F ++ +EEQEEY RE
Sbjct: 1573 -ALVSPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIRE 1631
Query: 424 GIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHGHYE 483
I W ++ + DN LI GIL +LD++C P +D TFL K H H+
Sbjct: 1632 QIDWQEITFADNQPCINLISLKPYGILRILDDQCCFP-QATDHTFLQKC------HYHHG 1684
Query: 484 SKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQHPLL 543
+ + + M L F I HYAGKVTY V F+DKN+D + +D+L +++ ++
Sbjct: 1685 ANPLYSKPK-----MPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVV 1739
Query: 544 RSLFPEGNPKQA-----------SLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPN 592
LF P+ A L + T A+F+ S+ L++ + +P ++RC+KPN
Sbjct: 1740 AHLFSSHAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPN 1799
Query: 593 EHQQRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGG 652
++ G F D+V Q RY G+LE VR+R+ G+ R + F++RY L G
Sbjct: 1800 HKKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLPANG 1859
Query: 653 DREGVEKVLGEL-SMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATL-IQKIYRG 710
D VL L + G +K+F++ + L+ L E R + LA L +Q+ RG
Sbjct: 1860 DM--CVSVLSRLCKVMPNMYRVGVSKLFLK--EHLYQLLESMREHVLNLAALTLQRCLRG 1915
Query: 711 WRCRTHYQLMRKSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNYRK 765
+ + ++ +R IL+ S RG + ++ Y +++ S++ ++ V + +R+ Y K
Sbjct: 1916 FFIKRRFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLK 1970
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 486 bits (1252), Expect = e-137
Identities = 309/822 (37%), Positives = 458/822 (55%), Gaps = 74/822 (9%)
Query: 8 VGVEDLVLLEPLVEESLLKNLQLRY-ENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQ 66
VG DL L L E ++L NL++R+ E+K IYTY G +++++NPY+QLPIYG I Y
Sbjct: 67 VGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYS 126
Query: 67 DYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGE 126
++ PHI+A+A AY+ + +R+Q I+++GESG+GKT +++ M Y A V G
Sbjct: 127 GQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGS 186
Query: 127 QVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKS 186
+ V++++L SNP+ EA GNAKT RN+NSSRFGKY +I FD + +G ++ YLLEKS
Sbjct: 187 NAH-VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKS 245
Query: 187 RLVKQLKGERNFHIFYQLLAGADEQLLKALKL-ERDTTGYAYLNHEVSRVDGMDDASSFR 245
R+V Q + ERN+HIFYQL A A + K LKL + Y + + ++G++D +
Sbjct: 246 RVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGN-TVIEGVNDRAEMV 304
Query: 246 AVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGI-RDGRGVREIGE 304
Q ++GF E+ V ++ + +L LGNV + A G S + D ++ E
Sbjct: 305 ETQKTFTLLGFKEDFQMDVFKILAAILHLGNV----QITAVGNERSSVSEDDSHLKVFCE 360
Query: 305 MVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINES 364
++GL S V + LC+R + T+ E VV + QA ARDALAK IY+ LFD+IV RIN++
Sbjct: 361 LLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQA 420
Query: 365 IKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKREG 424
++ G++ +GVLDIYGFE + NSFEQF INY NEKLQQ F K EQEEY +E
Sbjct: 421 LQFS-GKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKED 479
Query: 425 IPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHGHYES 484
IPWT +D++DN + LIE + GIL +LDEECL P +D +L KL Y +
Sbjct: 480 IPWTLIDFYDNQPVIDLIE-AKMGILELLDEECLLPH-GTDENWLQKL---------YNN 528
Query: 485 KVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQHPLLR 544
V +N + M + F I H+A KV Y F++KN D ++ L++ + ++ L
Sbjct: 529 FVNRNPLFEKPR-MSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCA 587
Query: 545 SLFPEGNP-------------------KQASLKRPPTAGAQFKSSVAILMKNLYSKSPNY 585
+ F E NP K S T G++F+SS+ +LM+ L + +P+Y
Sbjct: 588 NFFQE-NPTPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHY 646
Query: 586 IRCIKPNEHQQRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRST 645
+RCIKPN+ + +F S + Q R G+LE +R+ Y R Y F RY +L T
Sbjct: 647 VRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGIL--MT 704
Query: 646 WPHWNGGDREGVEK-VLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLI 704
+ D++ V K VL L S + FGKTKIF R+ + + YLE+ R +L+Q ++
Sbjct: 705 KQELSFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQ-VAYLEKLRLDKLRQSCVMV 763
Query: 705 QKIYRGWRCRTHYQLMRKSQILISSWFRGN--------------------MQKKC----- 739
QK RGW R + R++ ++I +FRG +QK C
Sbjct: 764 QKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLV 823
Query: 740 ---YGKIKASVLLIQAFVRGWKARKNYRKYFRSEAALTLADF 778
Y I+ + + +QA+ RG+ AR+ YRK A+ L +
Sbjct: 824 RSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKY 865
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 486 bits (1251), Expect = e-137
Identities = 298/824 (36%), Positives = 449/824 (54%), Gaps = 79/824 (9%)
Query: 8 VGVEDLVLLEPLVEESLLKNLQLRY-ENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQ 66
VG DL L L E ++L NL++R+ ++K IYTY G V++++NPY+QLPIYG + I Y
Sbjct: 69 VGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYS 128
Query: 67 DYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGE 126
++ PHI+A+A AY+ + +R+Q I+++GESG+GKT ++K M Y A V G
Sbjct: 129 GQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS 188
Query: 127 QVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKS 186
+ N V+E++L SNP++E+ GNAKT RN+NSSRFGKY++I FD + +G + YLLEKS
Sbjct: 189 EAN-VEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKS 247
Query: 187 RLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRV-DGMDDASSFR 245
R+V Q + ERN+HIFYQL A A K L+L + + Y S V +G+DDA
Sbjct: 248 RVVFQAEEERNYHIFYQLCASAKLPEFKMLRL-GNADNFNYTKQGGSPVIEGVDDAKEMA 306
Query: 246 AVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNV-LVADEFQASGIPASGIRDGRGVREIGE 304
+ A ++G SE + + + +L LGNV + + + IP + +
Sbjct: 307 HTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPK----HEPLCIFCD 362
Query: 305 MVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINES 364
++G++ EE+ LC R + TA E + ++ +QA ARDALAK+IY++LF+WIV+ +N++
Sbjct: 363 LMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQA 422
Query: 365 IKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKREG 424
+ + ++ +GVLDIYGFE E NSFEQF INY NEKLQQ F K EQEEY +E
Sbjct: 423 LHSAV-KQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQ 481
Query: 425 IPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHGHYES 484
IPWT +D++DN LIE ++ GIL +LDEEC P D+ N +K +E
Sbjct: 482 IPWTLIDFYDNQPCINLIE-SKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK 540
Query: 485 KVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQHPLLR 544
N F I H+A KV Y F++KN D +F + ++ + ++ +L
Sbjct: 541 PRLSN-----------KAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLP 589
Query: 545 SLFPE---------------------------GNPKQASLKRPPTAGAQFKSSVAILMKN 577
LF + G P Q + + T G QF++S+ +LM+
Sbjct: 590 ELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMET 649
Query: 578 LYSKSPNYIRCIKPNEHQQRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLER 637
L + +P+Y+RCIKPN+ + F Q R G+LE +R+ AG+ R Y F R
Sbjct: 650 LNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSR 709
Query: 638 YRLLSRSTWPHWNGGDREGVEKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRL 697
YR+L + ++ + VL +L + + FGKTKIF R+ + + YLE+ R +L
Sbjct: 710 YRVLMKQ--KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQ-VAYLEKLRADKL 766
Query: 698 QQLATLIQKIYRGWRCRTHYQLMRKSQILISSWFRGNMQKKCYGKI-------------- 743
+ IQK RGW R Y MRK+ I + + RG Q +CY K
Sbjct: 767 RAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRG-YQARCYAKFLRRTKAATIIQKYW 825
Query: 744 ------------KASVLLIQAFVRGWKARKNYRKYFRSEAALTL 775
+A+ +++Q+++RG+ AR YRK R A+ +
Sbjct: 826 RMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVII 869
Score = 39.3 bits (90), Expect = 0.020
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 4/104 (3%)
Query: 693 RRLRLQQLATLIQKIYRGWRCRTHYQLMRKSQILISSWFRGNMQKKCYGKIKASVLLIQA 752
R++ + A +IQK RGW RTHY+ + I + FR M K+ K+K ++
Sbjct: 858 RKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVER 917
Query: 753 FVRGWKARKNYRKYFRSEAALTLADFIYKSMVQKF--LLGLKNN 794
+ + +N K + + + + YK +V+K L G+ N+
Sbjct: 918 YKKLHIGMEN--KIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 486 bits (1251), Expect = e-137
Identities = 298/824 (36%), Positives = 449/824 (54%), Gaps = 79/824 (9%)
Query: 8 VGVEDLVLLEPLVEESLLKNLQLRY-ENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQ 66
VG DL L L E ++L NL++R+ ++K IYTY G V++++NPY+QLPIYG + I Y
Sbjct: 69 VGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYS 128
Query: 67 DYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGE 126
++ PHI+A+A AY+ + +R+Q I+++GESG+GKT ++K M Y A V G
Sbjct: 129 GQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS 188
Query: 127 QVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKS 186
+ N V+E++L SNP++E+ GNAKT RN+NSSRFGKY++I FD + +G + YLLEKS
Sbjct: 189 EAN-VEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKS 247
Query: 187 RLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRV-DGMDDASSFR 245
R+V Q + ERN+HIFYQL A A K L+L + + Y S V +G+DDA
Sbjct: 248 RVVFQAEEERNYHIFYQLCASAKLPEFKMLRL-GNADNFNYTKQGGSPVIEGVDDAKEMA 306
Query: 246 AVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNV-LVADEFQASGIPASGIRDGRGVREIGE 304
+ A ++G SE + + + +L LGNV + + + IP + +
Sbjct: 307 HTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPK----HEPLCIFCD 362
Query: 305 MVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINES 364
++G++ EE+ LC R + TA E + ++ +QA ARDALAK+IY++LF+WIV+ +N++
Sbjct: 363 LMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQA 422
Query: 365 IKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKREG 424
+ + ++ +GVLDIYGFE E NSFEQF INY NEKLQQ F K EQEEY +E
Sbjct: 423 LHSAV-KQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQ 481
Query: 425 IPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHGHYES 484
IPWT +D++DN LIE ++ GIL +LDEEC P D+ N +K +E
Sbjct: 482 IPWTLIDFYDNQPCINLIE-SKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK 540
Query: 485 KVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQHPLLR 544
N F I H+A KV Y F++KN D +F + ++ + ++ +L
Sbjct: 541 PRLSN-----------KAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLP 589
Query: 545 SLFPE---------------------------GNPKQASLKRPPTAGAQFKSSVAILMKN 577
LF + G P Q + + T G QF++S+ +LM+
Sbjct: 590 ELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMET 649
Query: 578 LYSKSPNYIRCIKPNEHQQRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLER 637
L + +P+Y+RCIKPN+ + F Q R G+LE +R+ AG+ R Y F R
Sbjct: 650 LNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSR 709
Query: 638 YRLLSRSTWPHWNGGDREGVEKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRL 697
YR+L + ++ + VL +L + + FGKTKIF R+ + + YLE+ R +L
Sbjct: 710 YRVLMKQ--KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQ-VAYLEKLRADKL 766
Query: 698 QQLATLIQKIYRGWRCRTHYQLMRKSQILISSWFRGNMQKKCYGKI-------------- 743
+ IQK RGW R Y MRK+ I + + RG Q +CY K
Sbjct: 767 RAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRG-YQARCYAKFLRRTKAATIIQKYW 825
Query: 744 ------------KASVLLIQAFVRGWKARKNYRKYFRSEAALTL 775
+A+ +++Q+++RG+ AR YRK R A+ +
Sbjct: 826 RMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVII 869
Score = 39.3 bits (90), Expect = 0.020
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 4/104 (3%)
Query: 693 RRLRLQQLATLIQKIYRGWRCRTHYQLMRKSQILISSWFRGNMQKKCYGKIKASVLLIQA 752
R++ + A +IQK RGW RTHY+ + I + FR M K+ K+K ++
Sbjct: 858 RKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVER 917
Query: 753 FVRGWKARKNYRKYFRSEAALTLADFIYKSMVQKF--LLGLKNN 794
+ + +N K + + + + YK +V+K L G+ N+
Sbjct: 918 YKKLHIGMEN--KIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 483 bits (1243), Expect = e-136
Identities = 281/763 (36%), Positives = 439/763 (57%), Gaps = 24/763 (3%)
Query: 9 GVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDY 68
GVED++ L L E +L+NL +RY + IYTY G+++++VNPYQ L IY PE I +Y +
Sbjct: 66 GVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNK 125
Query: 69 TFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGEQV 128
E+ PHI+A+A+ Y +++ RDQC +I+GESG+GKTE++KL++ ++AA+ G Q
Sbjct: 126 KIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG---QH 182
Query: 129 NSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKSRL 188
+ +++Q+L++ P+LEAFGNAKTIRN+NSSRFGKY+DI F+ +G+ G I YLLEKSR+
Sbjct: 183 SWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRV 242
Query: 189 VKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYL-NHEVSRVDGMDDASSFRAV 247
+Q ERN+H+FY +L G E K L L + + Y YL +G D+ + +
Sbjct: 243 CRQALDERNYHVFYCMLEGMSEDQKKKLGLGQ-ASDYNYLAMGNCITCEGRVDSQEYANI 301
Query: 248 QSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIGEMVG 307
+SAM V+ F++ E ++ ++ + +L LGN L + + A + + ++
Sbjct: 302 RSAMKVLMFTDTENWEISKLLAAILHLGN-LQYEARTFENLDACEVLFSPSLATAASLLE 360
Query: 308 LNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINESI-- 365
+N ++ L SRT+ T E V T L+ QA RDA K IY RLF WIV++IN +I
Sbjct: 361 VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK 420
Query: 366 --KVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKRE 423
+ ++ +G+LDI+GFE NSFEQ IN+ NE LQQ F+ K EQEEY E
Sbjct: 421 PPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLE 480
Query: 424 GIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHGHYE 483
I W +++ DN +I + I++++DEE P +D+T L KLN + +Y
Sbjct: 481 SIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP-KGTDTTMLHKLNSQHKLNANYI 539
Query: 484 SKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQHPLL 543
+ + F I H+AG V Y F++KN D L D++Q + +++ +
Sbjct: 540 PPKNNHETQ----------FGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFI 589
Query: 544 RSLFPEGNPKQA-SLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRGQFSS 602
+ +F A + KR PT +QFK S+ +LM+ L + P ++RCIKPNE ++ F
Sbjct: 590 KQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDR 649
Query: 603 DLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDREGVEKVLG 662
L Q RY G++E +R+RRAGY R + F+ERYR+L P + GD G + +
Sbjct: 650 HLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMA 709
Query: 663 ELSMSS-GELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHYQLMR 721
E + + + GKTKIF++ + LE +R + L+QK+ RG++ R+++ ++
Sbjct: 710 EAVLGTHDDWQIGKTKIFLKDHHDML-LEVERDKAITDRVILLQKVIRGFKDRSNFLKLK 768
Query: 722 KSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNYR 764
+ LI +RG+ +K YG ++ L +QA R K + YR
Sbjct: 769 NAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYR 811
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 483 bits (1243), Expect = e-136
Identities = 281/763 (36%), Positives = 439/763 (57%), Gaps = 24/763 (3%)
Query: 9 GVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDY 68
GVED++ L L E +L+NL +RY + IYTY G+++++VNPYQ L IY PE I +Y +
Sbjct: 66 GVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNK 125
Query: 69 TFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGEQV 128
E+ PHI+A+A+ Y +++ RDQC +I+GESG+GKTE++KL++ ++AA+ G Q
Sbjct: 126 KIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG---QH 182
Query: 129 NSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKSRL 188
+ +++Q+L++ P+LEAFGNAKTIRN+NSSRFGKY+DI F+ +G+ G I YLLEKSR+
Sbjct: 183 SWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRV 242
Query: 189 VKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYL-NHEVSRVDGMDDASSFRAV 247
+Q ERN+H+FY +L G E K L L + + Y YL +G D+ + +
Sbjct: 243 CRQALDERNYHVFYCMLEGMSEDQKKKLGLGQ-ASDYNYLAMGNCITCEGRVDSQEYANI 301
Query: 248 QSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIGEMVG 307
+SAM V+ F++ E ++ ++ + +L LGN L + + A + + ++
Sbjct: 302 RSAMKVLMFTDTENWEISKLLAAILHLGN-LQYEARTFENLDACEVLFSPSLATAASLLE 360
Query: 308 LNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINESI-- 365
+N ++ L SRT+ T E V T L+ QA RDA K IY RLF WIV++IN +I
Sbjct: 361 VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK 420
Query: 366 --KVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKRE 423
+ ++ +G+LDI+GFE NSFEQ IN+ NE LQQ F+ K EQEEY E
Sbjct: 421 PPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLE 480
Query: 424 GIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHGHYE 483
I W +++ DN +I + I++++DEE P +D+T L KLN + +Y
Sbjct: 481 SIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP-KGTDTTMLHKLNSQHKLNANYI 539
Query: 484 SKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQHPLL 543
+ + F I H+AG V Y F++KN D L D++Q + +++ +
Sbjct: 540 PPKNNHETQ----------FGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFI 589
Query: 544 RSLFPEGNPKQA-SLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRGQFSS 602
+ +F A + KR PT +QFK S+ +LM+ L + P ++RCIKPNE ++ F
Sbjct: 590 KQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDR 649
Query: 603 DLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDREGVEKVLG 662
L Q RY G++E +R+RRAGY R + F+ERYR+L P + GD G + +
Sbjct: 650 HLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMA 709
Query: 663 ELSMSS-GELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHYQLMR 721
E + + + GKTKIF++ + LE +R + L+QK+ RG++ R+++ ++
Sbjct: 710 EAVLGTHDDWQIGKTKIFLKDHHDML-LEVERDKAITDRVILLQKVIRGFKDRSNFLKLK 768
Query: 722 KSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNYR 764
+ LI +RG+ +K YG ++ L +QA R K + YR
Sbjct: 769 NAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYR 811
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 483 bits (1243), Expect = e-136
Identities = 281/763 (36%), Positives = 439/763 (57%), Gaps = 24/763 (3%)
Query: 9 GVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDY 68
GVED++ L L E +L+NL +RY + IYTY G+++++VNPYQ L IY PE I +Y +
Sbjct: 66 GVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNK 125
Query: 69 TFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGEQV 128
E+ PHI+A+A+ Y +++ RDQC +I+GESG+GKTE++KL++ ++AA+ G Q
Sbjct: 126 KIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG---QH 182
Query: 129 NSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKSRL 188
+ +++Q+L++ P+LEAFGNAKTIRN+NSSRFGKY+DI F+ +G+ G I YLLEKSR+
Sbjct: 183 SWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRV 242
Query: 189 VKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYL-NHEVSRVDGMDDASSFRAV 247
+Q ERN+H+FY +L G E K L L + + Y YL +G D+ + +
Sbjct: 243 CRQALDERNYHVFYCMLEGMSEDQKKKLGLGQ-ASDYNYLAMGNCITCEGRVDSQEYANI 301
Query: 248 QSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIGEMVG 307
+SAM V+ F++ E ++ ++ + +L LGN L + + A + + ++
Sbjct: 302 RSAMKVLMFTDTENWEISKLLAAILHLGN-LQYEARTFENLDACEVLFSPSLATAASLLE 360
Query: 308 LNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINESI-- 365
+N ++ L SRT+ T E V T L+ QA RDA K IY RLF WIV++IN +I
Sbjct: 361 VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK 420
Query: 366 --KVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKRE 423
+ ++ +G+LDI+GFE NSFEQ IN+ NE LQQ F+ K EQEEY E
Sbjct: 421 PPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLE 480
Query: 424 GIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHGHYE 483
I W +++ DN +I + I++++DEE P +D+T L KLN + +Y
Sbjct: 481 SIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP-KGTDTTMLHKLNSQHKLNANYI 539
Query: 484 SKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQHPLL 543
+ + F I H+AG V Y F++KN D L D++Q + +++ +
Sbjct: 540 PPKNNHETQ----------FGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFI 589
Query: 544 RSLFPEGNPKQA-SLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRGQFSS 602
+ +F A + KR PT +QFK S+ +LM+ L + P ++RCIKPNE ++ F
Sbjct: 590 KQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDR 649
Query: 603 DLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDREGVEKVLG 662
L Q RY G++E +R+RRAGY R + F+ERYR+L P + GD G + +
Sbjct: 650 HLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMA 709
Query: 663 ELSMSS-GELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHYQLMR 721
E + + + GKTKIF++ + LE +R + L+QK+ RG++ R+++ ++
Sbjct: 710 EAVLGTHDDWQIGKTKIFLKDHHDML-LEVERDKAITDRVILLQKVIRGFKDRSNFLKLK 768
Query: 722 KSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNYR 764
+ LI +RG+ +K YG ++ L +QA R K + YR
Sbjct: 769 NAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYR 811
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 471 bits (1213), Expect = e-132
Identities = 286/837 (34%), Positives = 446/837 (53%), Gaps = 71/837 (8%)
Query: 8 VGVEDLVLLEPLVEESLLKNLQLRY-ENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQ 66
VG DL L L E ++L NL++R+ E+ IYTY G V++++NPY+QLPIYG + I Y
Sbjct: 69 VGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYS 128
Query: 67 DYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGE 126
++ PHI+A+A AY+ + +++Q I+++GESG+GKT ++K M Y A V G
Sbjct: 129 GQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSAS 188
Query: 127 QVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKS 186
+ N ++E++L S+P++EA GNAKT RN+NSSRFGKY+ I FD + +G + YLLEKS
Sbjct: 189 ETN-IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKS 247
Query: 187 RLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVDGMDDASSFRA 246
R+V Q ERN+HIFYQL A A K L L + + ++G+DDA F
Sbjct: 248 RVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFEK 307
Query: 247 VQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIGEMV 306
+ A ++G E + ++ + +L LG+V + + + G S + ++
Sbjct: 308 TRQAFTLLGVKESHQMSIFKIIASILHLGSVAI--QAERDGDSCSISPQDVYLSNFCRLL 365
Query: 307 GLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINESIK 366
G+ ++E LC R + T E V +++ Q AR+ALAK+IY++LF WIV IN+++
Sbjct: 366 GVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALH 425
Query: 367 VGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKREGIP 426
+ ++ +GVLDIYGFE E NSFEQF INY NEKLQQ F K EQEEY +E IP
Sbjct: 426 TSL-KQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIP 484
Query: 427 WTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHGHYESKV 486
WT +D++DN LIE + GIL +LDEEC P +D + KL S H++
Sbjct: 485 WTLIDFYDNQPCIDLIE-AKLGILDLLDEECKVP-KGTDQNWAQKLYDRHSSSQHFQKPR 542
Query: 487 TQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQHPLLRSL 546
N + F I H+A KV Y F++KN D ++ + + + ++ PL+ L
Sbjct: 543 MSN-----------TAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADL 591
Query: 547 FPE------------GNPKQASLK--RPP----------TAGAQFKSSVAILMKNLYSKS 582
F + G+ + S++ RPP T G QF++S+ +LM+ L + +
Sbjct: 592 FHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATT 651
Query: 583 PNYIRCIKPNEHQQRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLS 642
P+Y+RCIKPN+ + F Q R G+LE +R+ AGY R Y F RYR+L
Sbjct: 652 PHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLV 711
Query: 643 RSTWPHWNGGDREGV-EKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLA 701
+ D++ + VL L + FG+TKIF R+ + + YLE+ R + +
Sbjct: 712 KKR--ELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQ-VAYLEKLRADKFRTAT 768
Query: 702 TLIQKIYRGWRCRTHYQLMRKSQILISSWFRGNMQKK----------------------- 738
+IQK RGW + Y ++ + + + + RG++ ++
Sbjct: 769 IMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRA 828
Query: 739 --CYGKIKASVLLIQAFVRGWKARKNYRKYFRSEAALTLADFIYKSMVQKFLLGLKN 793
Y +++ + ++IQAF R R+ YR+ A T+ + M ++ L++
Sbjct: 829 RQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRD 885
Score = 39.7 bits (91), Expect = 0.015
Identities = 18/49 (36%), Positives = 28/49 (57%)
Query: 684 KTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHYQLMRKSQILISSWFR 732
+ +F R++ ++ AT IQK RGW R H+Q +R + I+I FR
Sbjct: 847 RAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFR 895
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 469 bits (1207), Expect = e-132
Identities = 293/774 (37%), Positives = 443/774 (57%), Gaps = 44/774 (5%)
Query: 9 GVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLP-IYGPEFIAKYQD 67
GV+D+ L L S++ NL RY+ +IYTYIG+++ SVNPYQ + +Y P + +Y
Sbjct: 64 GVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSR 123
Query: 68 YTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKG-- 125
EL PHI+A+AN Y+ L R +QCILI+GESG+GKTE++KL++ +++ + +
Sbjct: 124 RHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQSLE 183
Query: 126 ----EQVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNY 181
E+ + V+ +L+S+P++EAFGNAKT+ NNNSSRFGK++ + KG+ GG I +Y
Sbjct: 184 LSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIVDY 243
Query: 182 LLEKSRLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVD-GMDD 240
LLEK+R+V+Q GERN+HIFY LLAG + + + L Y YLN D + D
Sbjct: 244 LLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLS-TPENYHYLNQSGCVEDKTISD 302
Query: 241 ASSFRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVR 300
SFR V +AM V+ FS+EE+R+V + + +L LGN+ EF +G + G
Sbjct: 303 QESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNI----EFITAGGAQVSFKTALG-- 356
Query: 301 EIGEMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNR 360
E++GL+ ++ AL R+M E+++T LNV QA +RD+LA +Y+ F+W++ +
Sbjct: 357 RSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKK 416
Query: 361 INESIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEY 420
IN IK E K +G+LDI+GFE E N FEQF INY NEKLQ+ F + EQ EY
Sbjct: 417 INSRIKG--NEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEY 474
Query: 421 KREGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKL-NQLFSKH 479
REG+ W +D+ DNG LIE + G+LA+++EE P +DST L KL +Q + H
Sbjct: 475 SREGLVWEDIDWIDNGECLDLIE-KKLGLLALINEESHFP-QATDSTLLEKLHSQHANNH 532
Query: 480 GHYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQ 539
+ + +V N F + HYAG+V Y+V ++KN D DLL + +++
Sbjct: 533 FYVKPRVAVNN------------FGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESR 580
Query: 540 HPLLRSLFP-------EGNPKQASLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPN 592
+ LF + K S R PT +QFK S+ LM L S +P ++RCIKPN
Sbjct: 581 FDFIYDLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPN 640
Query: 593 EHQQRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRS-TWPHWNG 651
+ QF +V Q RY G+LE VR+R+AGYA R+ + F +RY++L R+ P
Sbjct: 641 MQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE--- 697
Query: 652 GDREGVEKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGW 711
R +L S+ E GKTK+F+R LE++R + A +I+ G+
Sbjct: 698 DVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQ-KLEKRREEEVSHAAMVIRAHVLGF 756
Query: 712 RCRTHYQLMRKSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNYRK 765
R Y+ + ++I +R + ++ + +K + ++ Q +RG AR+ YR+
Sbjct: 757 LARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQ 810
>gi|122937512 myosin VIIB [Homo sapiens]
Length = 2116
Score = 464 bits (1194), Expect = e-130
Identities = 281/790 (35%), Positives = 438/790 (55%), Gaps = 44/790 (5%)
Query: 2 PLLEGSV-GVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPE 60
P+ SV GV+D++ L L E ++ NL +RY+ +IYTY G+++++VNP+Q LP+Y E
Sbjct: 58 PMHPNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLE 117
Query: 61 FIAKYQDYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAA 120
+ Y EL PH++A+AN Y S++ RDQC +I+GESG+GKTE +KL++ ++A
Sbjct: 118 QVQLYYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLAT 177
Query: 121 VCGKGEQVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITN 180
+ G Q + +++Q+L++NP+LEAFGNAKTIRN+NSSRFGKY+DI F+ G G I
Sbjct: 178 ISG---QHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQ 234
Query: 181 YLLEKSRLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVDGMDD 240
+LLEKSR+ +Q ERN+HIFY +L G + + L L + + + +G++D
Sbjct: 235 FLLEKSRVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLND 294
Query: 241 ASSFRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNV-LVADEFQASGIPASGIRDGRGV 299
A + ++SAM ++ FS+ E V+++ + +L LGNV +A F+ + AS + +
Sbjct: 295 AKDYAHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFE--NLDASDVMETPAF 352
Query: 300 REIGEMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVN 359
+ +++ + +E+ L T+ E V +LN+ QA RDA K IY LF WIV
Sbjct: 353 PTVMKLLEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVK 412
Query: 360 RINESIKVGIGEK----KKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKE 415
+IN +I + ++ +G+LDI+GFE E+NSFEQ IN+ NE LQQ F++
Sbjct: 413 KINAAIFTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTM 472
Query: 416 EQEEYKREGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQL 475
EQEEY+ E I W + Y DN L+ I+++LDEE P +D T L KLN +
Sbjct: 473 EQEEYRSENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFP-QGTDLTMLQKLNSV 531
Query: 476 FSKHGHYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAM 535
H +K + +D G I H+AG+V Y F++KN D+L D+L +
Sbjct: 532 -----HANNKAFLQPKNIHDARFG-----IAHFAGEVYYQAEGFLEKNRDVLSTDILTLV 581
Query: 536 WKAQHPLLRSLF---------PEGNPKQA-----------SLKRPPTAGAQFKSSVAILM 575
+ +++ LR +F G +QA S KRP T G+QFK S+ LM
Sbjct: 582 YSSKNKFLREIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLM 641
Query: 576 KNLYSKSPNYIRCIKPNEHQQRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFL 635
K L + P +IRCIKPNE+++ F +L Q RY G++E V +R++G+ R + F
Sbjct: 642 KILTNCQPYFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFS 701
Query: 636 ERYR-LLSRSTWPHWNGGDREGVEKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRR 694
+R+ LL + G R+ + + + GKTKIF+R + LE QR
Sbjct: 702 QRFGVLLPNAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTL-LEVQRS 760
Query: 695 LRLQQLATLIQKIYRGWRCRTHYQLMRKSQILISSWFRGNMQKKCYGKIKASVLLIQAFV 754
L + A IQK+ RG+R R + R++ + + +W+RG ++ + I +QA
Sbjct: 761 QVLDRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIA 820
Query: 755 RGWKARKNYR 764
R + Y+
Sbjct: 821 RSQPLARQYQ 830
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 448 bits (1153), Expect = e-125
Identities = 293/818 (35%), Positives = 444/818 (54%), Gaps = 49/818 (5%)
Query: 10 VEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDYT 69
+ED+ +L L E ++L NL+ RY + IYTY G ++VNPY+ LP+Y PE +A Y+
Sbjct: 87 IEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKK 146
Query: 70 FYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGEQVN 129
E PHI+++++ AYQ + +Q ILITGESG+GKT +K V+ Y A + G++
Sbjct: 147 RSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSK 206
Query: 130 --------SVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNY 181
++++Q++Q+NP LEAFGNAKT+RN+NSSRFGK++ I F G I Y
Sbjct: 207 KDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETY 266
Query: 182 LLEKSRLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVDGMDDA 241
LLEKSR++ QLK ER++HIFYQ+L+ +LL L + + YA+++ + V +DDA
Sbjct: 267 LLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVASIDDA 326
Query: 242 SSFRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDG-RGVR 300
A +A V+GF+ EE + ++T ++ GN+ +F+ DG
Sbjct: 327 EELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNM----KFKLKQREEQAEPDGTEEAD 382
Query: 301 EIGEMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNR 360
+ ++GLNS ++ + LC ++ E V NV Q YA ALAK +Y R+F+W+V R
Sbjct: 383 KSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTR 442
Query: 361 INESIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEY 420
IN +++ ++ +GVLDI GFEI + NSFEQ IN+ NEKLQQ F EQEEY
Sbjct: 443 INATLETK-QPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEY 501
Query: 421 KREGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKL-NQLFSKH 479
K+EGI WT +D+ + C + GI+++L+EEC+ P +D TF AKL + K
Sbjct: 502 KKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFP-KATDMTFKAKLFDNHLGKS 560
Query: 480 GHYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQ 539
+++ + + + F + HYAG V YN+ ++ KN D L ++ K+
Sbjct: 561 ANFQKPRNIKGKPE-------AHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSS 613
Query: 540 HPLLRSLF----------PEGNPKQASLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCI 589
LL +LF +G K T A + ++ LM NL S P+++RCI
Sbjct: 614 LKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCI 673
Query: 590 KPNEHQQRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHW 649
PNE + G + LV Q R G+LE +R+ R G+ +R YG F +RYR+L+ + P
Sbjct: 674 IPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEG 733
Query: 650 NGGD-REGVEKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIY 708
D R+G EK+L L + + FG TK+F ++ L LEE R RL ++ T IQ
Sbjct: 734 QFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKA-GLLGLLEEMRDERLSRIITRIQAQS 792
Query: 709 RGWRCRTHYQ--LMRKSQILISSW----FRGNMQ---KKCYGKIKASVLLIQAFVRGWKA 759
RG R Y+ L R+ +L+ W F G K Y KIK L+++ R +
Sbjct: 793 RGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKP---LLKSAEREKEM 849
Query: 760 RKNYRKYFRSEAALTLADFIYKSMVQKF--LLGLKNNL 795
++ R + AL ++ K + +K LL KN+L
Sbjct: 850 ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDL 887
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 443 bits (1139), Expect = e-124
Identities = 276/734 (37%), Positives = 411/734 (55%), Gaps = 46/734 (6%)
Query: 10 VEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDYT 69
VED+ L L E S+L NL+ RY + IYTY G + VNPY+ LPIY + + Y+
Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
Query: 70 FYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCG--KGEQ 127
+E+ PHIYA+A+ AY+S+ DQ IL TGESG+GKTE +K V+ Y+A V KG++
Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
Query: 128 VNSV----KEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLL 183
S+ ++QLLQ+NP+LEAFGNAKT++N+NSSRFGK++ I FD G +G I YLL
Sbjct: 207 DTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLL 266
Query: 184 EKSRLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVDGMDDASS 243
EKSR ++Q + ER FHIFY ++AGA E++ L LE Y +L++ + D
Sbjct: 267 EKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEM 325
Query: 244 FRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIG 303
F+ AMA++GFSEEE +L+V S VL+LGN++ E + + D +++
Sbjct: 326 FQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTD---QASMPDNTAAQKVC 382
Query: 304 EMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINE 363
++G+N + R++ + ++ ++ V A QA +A +ALAK Y RLF WI+ R+N+
Sbjct: 383 HLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNK 442
Query: 364 SIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKRE 423
++ + +G+LDI GFEI E NSFEQ INY NEKLQQ+F EQEEY+RE
Sbjct: 443 ALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQRE 502
Query: 424 GIPWTKVDY-FDNGIICKLIE--HNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHG 480
GI W +D+ D +LIE +N G+LA+LDEEC P +D +F+ KL H
Sbjct: 503 GIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFP-KATDKSFVEKLCTEQGSHP 561
Query: 481 HYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLL---FRDLLQA--- 534
+ Q ++ D T F I HYAGKV YN ++++ KN D L LL A
Sbjct: 562 KF-----QKPKQLKDKTE----FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSD 612
Query: 535 -----MWK---------AQHPLLRSLFPEGNPKQASLKRPPTAGAQFKSSVAILMKNLYS 580
+WK + S P + + + R T G +K + LM L +
Sbjct: 613 KFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFR--TVGQLYKEQLGKLMTTLRN 670
Query: 581 KSPNYIRCIKPNEHQQRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRL 640
+PN++RCI PN ++ G+ + LV Q R G+LE +R+ R G+ +R + F +RY +
Sbjct: 671 TTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEI 730
Query: 641 LSRSTWPHWNGGDREGVEKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQL 700
L+ + P ++ ++ L + G++KIF R+ L +LEE+R L++ +
Sbjct: 731 LAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLAHLEEERDLKITDV 789
Query: 701 ATLIQKIYRGWRCR 714
Q + RG+ R
Sbjct: 790 IMAFQAMCRGYLAR 803
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 443 bits (1139), Expect = e-124
Identities = 276/734 (37%), Positives = 411/734 (55%), Gaps = 46/734 (6%)
Query: 10 VEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDYT 69
VED+ L L E S+L NL+ RY + IYTY G + VNPY+ LPIY + + Y+
Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
Query: 70 FYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCG--KGEQ 127
+E+ PHIYA+A+ AY+S+ DQ IL TGESG+GKTE +K V+ Y+A V KG++
Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
Query: 128 VNSV----KEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLL 183
S+ ++QLLQ+NP+LEAFGNAKT++N+NSSRFGK++ I FD G +G I YLL
Sbjct: 207 DTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLL 266
Query: 184 EKSRLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVDGMDDASS 243
EKSR ++Q + ER FHIFY ++AGA E++ L LE Y +L++ + D
Sbjct: 267 EKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEM 325
Query: 244 FRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIG 303
F+ AMA++GFSEEE +L+V S VL+LGN++ E + + D +++
Sbjct: 326 FQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTD---QASMPDNTAAQKVC 382
Query: 304 EMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINE 363
++G+N + R++ + ++ ++ V A QA +A +ALAK Y RLF WI+ R+N+
Sbjct: 383 HLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNK 442
Query: 364 SIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKRE 423
++ + +G+LDI GFEI E NSFEQ INY NEKLQQ+F EQEEY+RE
Sbjct: 443 ALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQRE 502
Query: 424 GIPWTKVDY-FDNGIICKLIE--HNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHG 480
GI W +D+ D +LIE +N G+LA+LDEEC P +D +F+ KL H
Sbjct: 503 GIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFP-KATDKSFVEKLCTEQGSHP 561
Query: 481 HYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLL---FRDLLQA--- 534
+ Q ++ D T F I HYAGKV YN ++++ KN D L LL A
Sbjct: 562 KF-----QKPKQLKDKTE----FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSD 612
Query: 535 -----MWK---------AQHPLLRSLFPEGNPKQASLKRPPTAGAQFKSSVAILMKNLYS 580
+WK + S P + + + R T G +K + LM L +
Sbjct: 613 KFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFR--TVGQLYKEQLGKLMTTLRN 670
Query: 581 KSPNYIRCIKPNEHQQRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRL 640
+PN++RCI PN ++ G+ + LV Q R G+LE +R+ R G+ +R + F +RY +
Sbjct: 671 TTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEI 730
Query: 641 LSRSTWPHWNGGDREGVEKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQL 700
L+ + P ++ ++ L + G++KIF R+ L +LEE+R L++ +
Sbjct: 731 LAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLAHLEEERDLKITDV 789
Query: 701 ATLIQKIYRGWRCR 714
Q + RG+ R
Sbjct: 790 IMAFQAMCRGYLAR 803
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 440 bits (1132), Expect = e-123
Identities = 276/741 (37%), Positives = 411/741 (55%), Gaps = 53/741 (7%)
Query: 10 VEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDYT 69
VED+ L L E S+L NL+ RY + IYTY G + VNPY+ LPIY + + Y+
Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
Query: 70 FYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCG--KGEQ 127
+E+ PHIYA+A+ AY+S+ DQ IL TGESG+GKTE +K V+ Y+A V KG++
Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
Query: 128 VNSV-----------KEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGG 176
S+ ++QLLQ+NP+LEAFGNAKT++N+NSSRFGK++ I FD G +G
Sbjct: 207 DTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGA 266
Query: 177 VITNYLLEKSRLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVD 236
I YLLEKSR ++Q + ER FHIFY ++AGA E++ L LE Y +L++ +
Sbjct: 267 NIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIP 325
Query: 237 GMDDASSFRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDG 296
D F+ AMA++GFSEEE +L+V S VL+LGN++ E + + D
Sbjct: 326 AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTD---QASMPDN 382
Query: 297 RGVREIGEMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDW 356
+++ ++G+N + R++ + ++ ++ V A QA +A +ALAK Y RLF W
Sbjct: 383 TAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRW 442
Query: 357 IVNRINESIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEE 416
I+ R+N+++ + +G+LDI GFEI E NSFEQ INY NEKLQQ+F E
Sbjct: 443 ILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILE 502
Query: 417 QEEYKREGIPWTKVDY-FDNGIICKLIE--HNQRGILAMLDEECLRPGVVSDSTFLAKLN 473
QEEY+REGI W +D+ D +LIE +N G+LA+LDEEC P +D +F+ KL
Sbjct: 503 QEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFP-KATDKSFVEKLC 561
Query: 474 QLFSKHGHYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLL---FRD 530
H + Q ++ D T F I HYAGKV YN ++++ KN D L
Sbjct: 562 TEQGSHPKF-----QKPKQLKDKTE----FSIIHYAGKVDYNASAWLTKNMDPLNDNVTS 612
Query: 531 LLQA--------MWK---------AQHPLLRSLFPEGNPKQASLKRPPTAGAQFKSSVAI 573
LL A +WK + S P + + + R T G +K +
Sbjct: 613 LLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFR--TVGQLYKEQLGK 670
Query: 574 LMKNLYSKSPNYIRCIKPNEHQQRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGP 633
LM L + +PN++RCI PN ++ G+ + LV Q R G+LE +R+ R G+ +R +
Sbjct: 671 LMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQE 730
Query: 634 FLERYRLLSRSTWPHWNGGDREGVEKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQR 693
F +RY +L+ + P ++ ++ L + G++KIF R+ L +LEE+R
Sbjct: 731 FRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLAHLEEER 789
Query: 694 RLRLQQLATLIQKIYRGWRCR 714
L++ + Q + RG+ R
Sbjct: 790 DLKITDVIMAFQAMCRGYLAR 810
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 440 bits (1132), Expect = e-123
Identities = 276/741 (37%), Positives = 411/741 (55%), Gaps = 53/741 (7%)
Query: 10 VEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDYT 69
VED+ L L E S+L NL+ RY + IYTY G + VNPY+ LPIY + + Y+
Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
Query: 70 FYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCG--KGEQ 127
+E+ PHIYA+A+ AY+S+ DQ IL TGESG+GKTE +K V+ Y+A V KG++
Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
Query: 128 VNSV-----------KEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGG 176
S+ ++QLLQ+NP+LEAFGNAKT++N+NSSRFGK++ I FD G +G
Sbjct: 207 DTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGA 266
Query: 177 VITNYLLEKSRLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVD 236
I YLLEKSR ++Q + ER FHIFY ++AGA E++ L LE Y +L++ +
Sbjct: 267 NIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIP 325
Query: 237 GMDDASSFRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDG 296
D F+ AMA++GFSEEE +L+V S VL+LGN++ E + + D
Sbjct: 326 AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTD---QASMPDN 382
Query: 297 RGVREIGEMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDW 356
+++ ++G+N + R++ + ++ ++ V A QA +A +ALAK Y RLF W
Sbjct: 383 TAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRW 442
Query: 357 IVNRINESIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEE 416
I+ R+N+++ + +G+LDI GFEI E NSFEQ INY NEKLQQ+F E
Sbjct: 443 ILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILE 502
Query: 417 QEEYKREGIPWTKVDY-FDNGIICKLIE--HNQRGILAMLDEECLRPGVVSDSTFLAKLN 473
QEEY+REGI W +D+ D +LIE +N G+LA+LDEEC P +D +F+ KL
Sbjct: 503 QEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFP-KATDKSFVEKLC 561
Query: 474 QLFSKHGHYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLL---FRD 530
H + Q ++ D T F I HYAGKV YN ++++ KN D L
Sbjct: 562 TEQGSHPKF-----QKPKQLKDKTE----FSIIHYAGKVDYNASAWLTKNMDPLNDNVTS 612
Query: 531 LLQA--------MWK---------AQHPLLRSLFPEGNPKQASLKRPPTAGAQFKSSVAI 573
LL A +WK + S P + + + R T G +K +
Sbjct: 613 LLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFR--TVGQLYKEQLGK 670
Query: 574 LMKNLYSKSPNYIRCIKPNEHQQRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGP 633
LM L + +PN++RCI PN ++ G+ + LV Q R G+LE +R+ R G+ +R +
Sbjct: 671 LMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQE 730
Query: 634 FLERYRLLSRSTWPHWNGGDREGVEKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQR 693
F +RY +L+ + P ++ ++ L + G++KIF R+ L +LEE+R
Sbjct: 731 FRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLAHLEEER 789
Query: 694 RLRLQQLATLIQKIYRGWRCR 714
L++ + Q + RG+ R
Sbjct: 790 DLKITDVIMAFQAMCRGYLAR 810
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 439 bits (1129), Expect = e-123
Identities = 274/732 (37%), Positives = 404/732 (55%), Gaps = 42/732 (5%)
Query: 10 VEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDYT 69
VED+ L L E S+L NL+ RY + IYTY G + +NPY+ LPIY I Y+
Sbjct: 87 VEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKK 146
Query: 70 FYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCG--KGEQ 127
+E+ PHIYA++ AY+ + DQ IL TGESG+GKTE +K V+ Y+A V KG +
Sbjct: 147 RHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRK 206
Query: 128 VNSV----KEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLL 183
+++ + QLLQ+NP+LE+FGNAKT++N+NSSRFGK++ I FD G +G I YLL
Sbjct: 207 DHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLL 266
Query: 184 EKSRLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVDGMDDASS 243
EKSR V+Q K ER FHIFYQLL+GA E L L LE Y +L++ + G D +
Sbjct: 267 EKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLE-GFNNYRFLSNGYIPIPGQQDKDN 325
Query: 244 FRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIG 303
F+ AM ++GFS EEI +L+V S VL+ GN+ E + + + +++
Sbjct: 326 FQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTD---QASMPENTVAQKLC 382
Query: 304 EMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINE 363
++G+N E RA+ + ++ ++ V A QA +A +ALAK Y RLF W+V+RIN+
Sbjct: 383 HLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINK 442
Query: 364 SIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKRE 423
++ + +G+LDI GFEI E NSFEQ INY NEKLQQ+F EQEEY+RE
Sbjct: 443 ALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQRE 502
Query: 424 GIPWTKVDY-FDNGIICKLIEH--NQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHG 480
GI W +D+ D LIE N G+LA+LDEEC P +D TF+ KL Q H
Sbjct: 503 GIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFP-KATDKTFVEKLVQEQGSHS 561
Query: 481 HYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQH 540
++ K Q + + F I HYAGKV Y ++ KN D L ++ + ++
Sbjct: 562 KFQ-KPRQLKDK--------ADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSD 612
Query: 541 PLLRSLFPE------------------GNPKQASLKRPPTAGAQFKSSVAILMKNLYSKS 582
+ L+ + G+ + T G +K S+ LM L + +
Sbjct: 613 RFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTN 672
Query: 583 PNYIRCIKPNEHQQRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLS 642
PN++RCI PN ++ G+ LV Q R G+LE +R+ R G+ +R + F +RY +L+
Sbjct: 673 PNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILT 732
Query: 643 RSTWPHWNGGDREGVEKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLAT 702
+ P ++ E+++ L + G++KIF R+ L +LEE+R L++ +
Sbjct: 733 PNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRA-GVLAHLEEERDLKITDIII 791
Query: 703 LIQKIYRGWRCR 714
Q + RG+ R
Sbjct: 792 FFQAVCRGYLAR 803
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 439 bits (1129), Expect = e-123
Identities = 272/749 (36%), Positives = 412/749 (55%), Gaps = 45/749 (6%)
Query: 10 VEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDYT 69
+ED+ +L L E ++L NL+ RY IYTY G ++VNPY+ LP+Y E +A Y+
Sbjct: 87 IEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKK 146
Query: 70 FYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVC-----GK 124
E PHI+++++ AYQ + +Q ILITGESG+GKT +K V+ Y A++ GK
Sbjct: 147 RSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGK 206
Query: 125 GEQVNSVK----EQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITN 180
+ N+ K +Q++Q+NP LEAFGNAKT+RN+NSSRFGK++ I F G I
Sbjct: 207 KDNANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIET 266
Query: 181 YLLEKSRLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVDGMDD 240
YLLEKSR++ QLK ERN+HIFYQ+L+ +LL L + + YA+++ V +DD
Sbjct: 267 YLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVASIDD 326
Query: 241 ASSFRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVR 300
+ A SA V+GF+ EE V ++T ++ GN+ + + G D
Sbjct: 327 SEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTED---AD 383
Query: 301 EIGEMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNR 360
+ ++GLNS ++ + LC ++ E V +V Q Y+ ALAK +Y ++F+W+V R
Sbjct: 384 KSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTR 443
Query: 361 INESIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEY 420
IN +++ ++ +GVLDI GFEI + NSFEQ IN+ NEKLQQ F EQEEY
Sbjct: 444 INATLETK-QPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEY 502
Query: 421 KREGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKL--NQLFSK 478
K+EGI WT +D+ + C + GI+++L+EEC+ P +D TF AKL N L
Sbjct: 503 KKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFP-KATDMTFKAKLYDNHLGKS 561
Query: 479 HGHYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKA 538
+ + + + Q + F + HYAG V YN+ +++KN D L ++ K+
Sbjct: 562 NNFQKPRNIKGKQEAH--------FSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKS 613
Query: 539 QHPLLRSLFPE--------------GNPKQASLKRPPTAGAQFKSSVAILMKNLYSKSPN 584
L+ +LF G K +S + T A + ++ LM NL + P+
Sbjct: 614 SLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQ---TVSALHRENLNKLMTNLRTTHPH 670
Query: 585 YIRCIKPNEHQQRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRS 644
++RCI PNE + G + LV Q R G+LE +R+ R G+ +R YG F +RYR+L+
Sbjct: 671 FVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPV 730
Query: 645 TWPHWNGGD-REGVEKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATL 703
P D R+G EK+L L + + FG TK+F ++ L LEE R RL ++ T
Sbjct: 731 AIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKA-GLLGLLEEMRDERLSRIITR 789
Query: 704 IQKIYRGWRCRTHYQ--LMRKSQILISSW 730
+Q RG R ++ + R+ +L+ W
Sbjct: 790 MQAQARGQLMRIEFKKIVERRDALLVIQW 818
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 434 bits (1117), Expect = e-121
Identities = 279/762 (36%), Positives = 416/762 (54%), Gaps = 52/762 (6%)
Query: 11 EDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDYTF 70
ED+ L L E S+L NL+ RY + IYTY G + +NPY+QLPIY + Y+
Sbjct: 108 EDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167
Query: 71 YELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCG--KGEQV 128
+E+ PH+YA+ AY+S+ DQ IL TGESG+GKTE +K V+ Y+A V KG +
Sbjct: 168 HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227
Query: 129 NSV----KEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLE 184
V + QLLQ+NP+LEAFGNAKT++N+NSSRFGK++ I FD G +G I YLLE
Sbjct: 228 PGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLE 287
Query: 185 KSRLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVDGMDDASSF 244
KSR ++Q K E +FHIFYQLL GA EQL L LE + Y +L + S G + F
Sbjct: 288 KSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLE-PCSHYRFLTNGPSSSPGQE-RELF 345
Query: 245 RAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIGE 304
+ ++ V+GFS EEI +L + S VL+ GN+ + E + + D +++
Sbjct: 346 QETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTD---QATMPDNTAAQKLCR 402
Query: 305 MVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINES 364
++GL + RAL + ++ ++ V A QA +A +ALAK Y RLF W+V R+N +
Sbjct: 403 LLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRA 462
Query: 365 IKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKREG 424
+ + +G+LDI GFEI + NSFEQ INY NEKLQQ+F EQEEY+REG
Sbjct: 463 LDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 522
Query: 425 IPWTKVDY-FDNGIICKLIEH--NQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHGH 481
IPWT +D+ D LIE N G+LA+LDEEC P +D +F+ K+ Q + GH
Sbjct: 523 IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFP-KATDKSFVEKVAQ--EQGGH 579
Query: 482 YESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQHP 541
+ + ++ + Q D F + HYAGKV Y ++ KN D L ++ + ++
Sbjct: 580 PKFQRPRHLRDQAD-------FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDR 632
Query: 542 LLRSLF-------------------PEGNPKQASLKRPPTAGAQFKSSVAILMKNLYSKS 582
L ++ P G P++ + T G +K S++ LM L + +
Sbjct: 633 LTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFR---TVGQLYKESLSRLMATLSNTN 689
Query: 583 PNYIRCIKPNEHQQRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLS 642
P+++RCI PN ++ G+ LV Q R G+LE +R+ R G+ +R + F +RY +L+
Sbjct: 690 PSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILT 749
Query: 643 RSTWPHWNGGDREGVEKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLAT 702
+ P ++ EK++ L + G++KIF R+ L LEE+R L++ +
Sbjct: 750 PNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRA-GVLAQLEEERDLKVTDIIV 808
Query: 703 LIQKIYRGWRCRTHYQLMRKSQILISSWFRGNMQKKCYGKIK 744
Q RG+ R +Q ++ Q + MQ+ C +K
Sbjct: 809 SFQAAARGYLARRAFQKRQQQQSALRV-----MQRNCAAYLK 845
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,147,214
Number of Sequences: 37866
Number of extensions: 1537105
Number of successful extensions: 4389
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 3754
Number of HSP's gapped (non-prelim): 224
length of query: 1043
length of database: 18,247,518
effective HSP length: 112
effective length of query: 931
effective length of database: 14,006,526
effective search space: 13040075706
effective search space used: 13040075706
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.