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Search of human proteins with 4885409
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4885409 high density lipoprotein binding protein [Homo
sapiens]
(1268 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4885409 high density lipoprotein binding protein [Homo sapiens] 2486 0.0
gi|42716280 high density lipoprotein binding protein [Homo sapiens] 2486 0.0
gi|122937472 bicaudal C homolog 1 [Homo sapiens] 77 1e-13
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 69 4e-11
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 63 2e-09
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 62 5e-09
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ... 60 1e-08
gi|17402900 far upstream element-binding protein [Homo sapiens] 60 2e-08
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 58 5e-08
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1... 57 1e-07
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 57 1e-07
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 55 3e-07
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 55 3e-07
gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 55 3e-07
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 52 5e-06
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 52 5e-06
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 51 8e-06
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 50 1e-05
gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 50 1e-05
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 50 1e-05
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 50 2e-05
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 49 4e-05
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 48 7e-05
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 47 9e-05
gi|147902746 MEX3A protein [Homo sapiens] 47 1e-04
gi|165905613 ring finger and KH domain containing 1 [Homo sapiens] 45 3e-04
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 44 0.001
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 44 0.001
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ... 44 0.001
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 43 0.002
>gi|4885409 high density lipoprotein binding protein [Homo sapiens]
Length = 1268
Score = 2486 bits (6443), Expect = 0.0
Identities = 1268/1268 (100%), Positives = 1268/1268 (100%)
Query: 1 MSSVAVLTQESFAEHRSGLVPQQIKVATLNSEEESDPPTYKDAFPPLPEKAACLESAQEP 60
MSSVAVLTQESFAEHRSGLVPQQIKVATLNSEEESDPPTYKDAFPPLPEKAACLESAQEP
Sbjct: 1 MSSVAVLTQESFAEHRSGLVPQQIKVATLNSEEESDPPTYKDAFPPLPEKAACLESAQEP 60
Query: 61 AGAWGNKIRPIKASVITQVFHVPLEERKYKDMNQFGEGEQAKICLEIMQRTGAHLELSLA 120
AGAWGNKIRPIKASVITQVFHVPLEERKYKDMNQFGEGEQAKICLEIMQRTGAHLELSLA
Sbjct: 61 AGAWGNKIRPIKASVITQVFHVPLEERKYKDMNQFGEGEQAKICLEIMQRTGAHLELSLA 120
Query: 121 KDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVAIPKEHHRFVIGKNGEKLQDLELKT 180
KDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVAIPKEHHRFVIGKNGEKLQDLELKT
Sbjct: 121 KDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVAIPKEHHRFVIGKNGEKLQDLELKT 180
Query: 181 ATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVERLEVEKAFHPFIAGP 240
ATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVERLEVEKAFHPFIAGP
Sbjct: 181 ATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVERLEVEKAFHPFIAGP 240
Query: 241 YNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAV 300
YNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAV
Sbjct: 241 YNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAV 300
Query: 301 EVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAK 360
EVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAK
Sbjct: 301 EVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAK 360
Query: 361 ANSFTVSSVAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFTEGEDKITLEGPTEDVNVA 420
ANSFTVSSVAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFTEGEDKITLEGPTEDVNVA
Sbjct: 361 ANSFTVSSVAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFTEGEDKITLEGPTEDVNVA 420
Query: 421 QEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNL 480
QEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNL
Sbjct: 421 QEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNL 480
Query: 481 IRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEV 540
IRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEV
Sbjct: 481 IRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEV 540
Query: 541 IINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKG 600
IINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKG
Sbjct: 541 IINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKG 600
Query: 601 GANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIAEVEVSI 660
GANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIAEVEVSI
Sbjct: 601 GANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIAEVEVSI 660
Query: 661 PAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLA 720
PAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLA
Sbjct: 661 PAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLA 720
Query: 721 EEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAEDKDQDLITIIGKE 780
EEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAEDKDQDLITIIGKE
Sbjct: 721 EEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAEDKDQDLITIIGKE 780
Query: 781 DAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRS 840
DAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRS
Sbjct: 781 DAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRS 840
Query: 841 GTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFHRSVMGPKGSRIQQIT 900
GTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFHRSVMGPKGSRIQQIT
Sbjct: 841 GTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFHRSVMGPKGSRIQQIT 900
Query: 901 RDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGREAKDCDPGSPRRCDIIIISGRKEKC 960
RDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGREAKDCDPGSPRRCDIIIISGRKEKC
Sbjct: 901 RDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGREAKDCDPGSPRRCDIIIISGRKEKC 960
Query: 961 EAAKEALEALVPVTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAI 1020
EAAKEALEALVPVTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAI
Sbjct: 961 EAAKEALEALVPVTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAI 1020
Query: 1021 TGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRL 1080
TGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRL
Sbjct: 1021 TGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRL 1080
Query: 1081 EHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQMVSEDVPLDHRVHA 1140
EHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQMVSEDVPLDHRVHA
Sbjct: 1081 EHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQMVSEDVPLDHRVHA 1140
Query: 1141 RIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEEEYLAD 1200
RIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEEEYLAD
Sbjct: 1141 RIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEEEYLAD 1200
Query: 1201 VVDSEALQVYMKPPAHEEAKAPSRGFVVRDAPWTASSSEKAPDMSSSEEFPSFGAQVAPK 1260
VVDSEALQVYMKPPAHEEAKAPSRGFVVRDAPWTASSSEKAPDMSSSEEFPSFGAQVAPK
Sbjct: 1201 VVDSEALQVYMKPPAHEEAKAPSRGFVVRDAPWTASSSEKAPDMSSSEEFPSFGAQVAPK 1260
Query: 1261 TLPWGPKR 1268
TLPWGPKR
Sbjct: 1261 TLPWGPKR 1268
>gi|42716280 high density lipoprotein binding protein [Homo sapiens]
Length = 1268
Score = 2486 bits (6443), Expect = 0.0
Identities = 1268/1268 (100%), Positives = 1268/1268 (100%)
Query: 1 MSSVAVLTQESFAEHRSGLVPQQIKVATLNSEEESDPPTYKDAFPPLPEKAACLESAQEP 60
MSSVAVLTQESFAEHRSGLVPQQIKVATLNSEEESDPPTYKDAFPPLPEKAACLESAQEP
Sbjct: 1 MSSVAVLTQESFAEHRSGLVPQQIKVATLNSEEESDPPTYKDAFPPLPEKAACLESAQEP 60
Query: 61 AGAWGNKIRPIKASVITQVFHVPLEERKYKDMNQFGEGEQAKICLEIMQRTGAHLELSLA 120
AGAWGNKIRPIKASVITQVFHVPLEERKYKDMNQFGEGEQAKICLEIMQRTGAHLELSLA
Sbjct: 61 AGAWGNKIRPIKASVITQVFHVPLEERKYKDMNQFGEGEQAKICLEIMQRTGAHLELSLA 120
Query: 121 KDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVAIPKEHHRFVIGKNGEKLQDLELKT 180
KDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVAIPKEHHRFVIGKNGEKLQDLELKT
Sbjct: 121 KDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVAIPKEHHRFVIGKNGEKLQDLELKT 180
Query: 181 ATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVERLEVEKAFHPFIAGP 240
ATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVERLEVEKAFHPFIAGP
Sbjct: 181 ATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVERLEVEKAFHPFIAGP 240
Query: 241 YNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAV 300
YNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAV
Sbjct: 241 YNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAV 300
Query: 301 EVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAK 360
EVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAK
Sbjct: 301 EVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAK 360
Query: 361 ANSFTVSSVAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFTEGEDKITLEGPTEDVNVA 420
ANSFTVSSVAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFTEGEDKITLEGPTEDVNVA
Sbjct: 361 ANSFTVSSVAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFTEGEDKITLEGPTEDVNVA 420
Query: 421 QEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNL 480
QEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNL
Sbjct: 421 QEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNL 480
Query: 481 IRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEV 540
IRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEV
Sbjct: 481 IRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEV 540
Query: 541 IINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKG 600
IINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKG
Sbjct: 541 IINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKG 600
Query: 601 GANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIAEVEVSI 660
GANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIAEVEVSI
Sbjct: 601 GANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIAEVEVSI 660
Query: 661 PAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLA 720
PAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLA
Sbjct: 661 PAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLA 720
Query: 721 EEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAEDKDQDLITIIGKE 780
EEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAEDKDQDLITIIGKE
Sbjct: 721 EEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAEDKDQDLITIIGKE 780
Query: 781 DAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRS 840
DAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRS
Sbjct: 781 DAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRS 840
Query: 841 GTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFHRSVMGPKGSRIQQIT 900
GTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFHRSVMGPKGSRIQQIT
Sbjct: 841 GTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFHRSVMGPKGSRIQQIT 900
Query: 901 RDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGREAKDCDPGSPRRCDIIIISGRKEKC 960
RDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGREAKDCDPGSPRRCDIIIISGRKEKC
Sbjct: 901 RDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGREAKDCDPGSPRRCDIIIISGRKEKC 960
Query: 961 EAAKEALEALVPVTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAI 1020
EAAKEALEALVPVTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAI
Sbjct: 961 EAAKEALEALVPVTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAI 1020
Query: 1021 TGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRL 1080
TGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRL
Sbjct: 1021 TGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRL 1080
Query: 1081 EHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQMVSEDVPLDHRVHA 1140
EHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQMVSEDVPLDHRVHA
Sbjct: 1081 EHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQMVSEDVPLDHRVHA 1140
Query: 1141 RIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEEEYLAD 1200
RIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEEEYLAD
Sbjct: 1141 RIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEEEYLAD 1200
Query: 1201 VVDSEALQVYMKPPAHEEAKAPSRGFVVRDAPWTASSSEKAPDMSSSEEFPSFGAQVAPK 1260
VVDSEALQVYMKPPAHEEAKAPSRGFVVRDAPWTASSSEKAPDMSSSEEFPSFGAQVAPK
Sbjct: 1201 VVDSEALQVYMKPPAHEEAKAPSRGFVVRDAPWTASSSEKAPDMSSSEEFPSFGAQVAPK 1260
Query: 1261 TLPWGPKR 1268
TLPWGPKR
Sbjct: 1261 TLPWGPKR 1268
>gi|122937472 bicaudal C homolog 1 [Homo sapiens]
Length = 974
Score = 77.0 bits (188), Expect = 1e-13
Identities = 88/423 (20%), Positives = 180/423 (42%), Gaps = 66/423 (15%)
Query: 705 PSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGK-----IRKVRDSTGA 759
P S+ + LH E + + F VD R K E +G G+ +K+ + T
Sbjct: 29 PGSEDDLVAGATLHSPEWSEER-FRVD-RKKLEAMLQAAAEGKGRSGEDFFQKIMEETNT 86
Query: 760 RVIFPA-----AEDKDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRH 814
++ +P+ A+ K I + GK++ V+EA++ + +++ N V M V H H
Sbjct: 87 QIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSH 146
Query: 815 FVIRRGQVLREIAEEYGGVMVSFPRS-----GTQSDKVTLKGAKDCVEAAKKRIQEIIED 869
+ + G ++++ EE G + FP S +S++V++ G VE+A+ RI+E++
Sbjct: 147 VIGKGGNNIKKVMEE-TGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIRELL-- 203
Query: 870 LEAQVTLECAIP-QKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQENG 928
+ L +P + V P IQ I++ +++ + F ++ + ++ +V+ +
Sbjct: 204 ---PLVLMFELPIAGILQPVPDPNSPSIQHISQTYNISVSF--KQRSRMYGATVIVRGSQ 258
Query: 929 DEAGEGREAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYVI 988
+ +E G E +L + +PV+ ++++ H +++
Sbjct: 259 NNTSAVKE------------------GTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMM 300
Query: 989 GQKGSGIRKMMDEFEVNIHVPAPE--LQSDIIAITGLAANLDRAKAGLLERVKELQAEQE 1046
G+ GS I+ +M IH P P + + + G ++ A+ L+ + +
Sbjct: 301 GRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLMGCLPLV----- 355
Query: 1047 DRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGY 1106
+ K + VDP++ I Q+ + DV I K QP + +
Sbjct: 356 --LMFDMKEEIEVDPQF-----------IAQLMEQLDVFISIKPKP--KQPSKSVIVKSV 400
Query: 1107 EKN 1109
E+N
Sbjct: 401 ERN 403
Score = 71.6 bits (174), Expect = 4e-12
Identities = 64/230 (27%), Positives = 108/230 (46%), Gaps = 21/230 (9%)
Query: 548 AQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKGGANIKKI 607
++K +++ G K +V++ K M V D N ++ + + H ++IGKGG NIKK+
Sbjct: 100 SKKDPHIKVSGKKEDVKEA-KEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKV 158
Query: 608 REESNTKIDLPAENSN-----SETIIITGKRANCEAARSRILSIQKDLANIAEVEVSIPA 662
EE+ I P N N S + I G+ A E+AR RI + L + E+ I A
Sbjct: 159 MEETGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIREL---LPLVLMFELPI-A 214
Query: 663 KLHNSLIGTKGRLIRSIMEECGGVHIHFPVEG-SGSDTVVIRGPSSDVEKAKK----QLL 717
+ + I+ I + + + F TV++RG ++ K+ L
Sbjct: 215 GILQPVPDPNSPSIQHI-SQTYNISVSFKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLE 273
Query: 718 HLAEEKQTK---SFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFP 764
HLA + S +DI A ++H F++G+ G I+ + TGA++ FP
Sbjct: 274 HLAGSLASAIPVSTQLDIAA--QHHLFMMGRNGSNIKHIMQRTGAQIHFP 321
Score = 70.1 bits (170), Expect = 1e-11
Identities = 70/282 (24%), Positives = 127/282 (45%), Gaps = 30/282 (10%)
Query: 408 ITLEGPTEDVNVAQEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKV 467
I + G EDV A+E I ++ NR+ +++++ H H H+IGK G NI ++ ++
Sbjct: 106 IKVSGKKEDVKEAKEMIMSVLDTKSNRVT-LKMDVSHTEHSHVIGKGGNNIKKVMEETGC 164
Query: 468 SVRIPP-----DSEKSNLIRIEGDPQGVQQAK---RELLELASRMENERTKDLIIEQRFH 519
+ P +EKSN + I G P GV+ A+ RELL L E L
Sbjct: 165 HIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGIL------- 217
Query: 520 RTIIGQKGERIREIRDKFPEVIINFPDPAQK-SDIVQLRGPKNE---VEKCTKYMQKMVA 575
+ + I+ I + + ++F ++ V +RG +N V++ T + + +A
Sbjct: 218 QPVPDPNSPSIQHISQTY-NISVSFKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLA 276
Query: 576 DLVENSYSIS--VPIFKQFHKNIIGKGGANIKKIREESNTKIDL--PAENSNSETIIITG 631
+ ++ +S + I Q H ++G+ G+NIK I + + +I P+ T+ + G
Sbjct: 277 GSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQG 336
Query: 632 KRANCEAARSRI-----LSIQKDLANIAEVEVSIPAKLHNSL 668
+ AR + L + D+ EV+ A+L L
Sbjct: 337 TIESVCLARQYLMGCLPLVLMFDMKEEIEVDPQFIAQLMEQL 378
Score = 68.6 bits (166), Expect = 4e-11
Identities = 74/342 (21%), Positives = 144/342 (42%), Gaps = 59/342 (17%)
Query: 700 VVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGA 759
+ + G DV++AK+ ++ + + K + T+ + H +IGKGG I+KV + TG
Sbjct: 106 IKVSGKKEDVKEAKEMIMSVLDTKSNR-VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGC 164
Query: 760 RVIFPAAEDKDQ----DLITIIGKEDAVREAQ---KELEALIQNLDNVVEDSMLVDPKHH 812
+ FP + +Q + ++I G+ V A+ +EL L+ + + + P +
Sbjct: 165 HIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPVPDPN 224
Query: 813 RHFVIRRGQVLREIAEEYGGVMVSF-PRSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLE 871
++ I++ Y + VSF RS V ++G+++ A K+ ++E L
Sbjct: 225 -------SPSIQHISQTY-NISVSFKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLA 276
Query: 872 AQ------VTLECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQ 925
V+ + I + H +MG GS I+ I + QI FP
Sbjct: 277 GSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFP--------------- 321
Query: 926 ENGDEAGEGREAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHR 985
DP +P++ + + G E A++ L +P+ + FD+ +
Sbjct: 322 ---------------DPSNPQKKSTVYLQGTIESVCLARQYLMGCLPLVL----MFDM-K 361
Query: 986 YVIGQKGSGIRKMMDEFEVNIHV-PAPELQSDIIAITGLAAN 1026
I I ++M++ +V I + P P+ S + + + N
Sbjct: 362 EEIEVDPQFIAQLMEQLDVFISIKPKPKQPSKSVIVKSVERN 403
Score = 65.5 bits (158), Expect = 3e-10
Identities = 69/325 (21%), Positives = 144/325 (44%), Gaps = 54/325 (16%)
Query: 951 IIISGRKEKCEAAKEALEALVP-----VTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVN 1005
I +SG+KE + AKE + +++ VT++++V H +VIG+ G+ I+K+M+E +
Sbjct: 106 IKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCH 165
Query: 1006 IHVPAPEL-----QSDIIAITGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLSVT-- 1058
IH P +S+ ++I G A ++ A+ R++EL + F+L +
Sbjct: 166 IHFPDSNRNNQAEKSNQVSIAGQPAGVESARV----RIRELLP-----LVLMFELPIAGI 216
Query: 1059 VDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAIL 1118
+ P P I I +++++ F K + + G + NT A ++
Sbjct: 217 LQPVPDP-----NSPSIQHISQTYNISVSF--KQRSRMYGATVIVRGSQNNTSAVKEGTA 269
Query: 1119 RIVGELEQMVSEDVPLDHRV------HARIIGARGKAIRKIMDEFKVDIRFPQSGAPD-P 1171
++ L ++ +P+ ++ H ++G G I+ IM I FP P
Sbjct: 270 MLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKK 329
Query: 1172 NCVTVTGLPENVEEAIDHI---------------LNLEEEYLADVVDSEALQVYMKPPAH 1216
+ V + G E+V A ++ + ++ +++A +++ + + +KP
Sbjct: 330 STVYLQGTIESVCLARQYLMGCLPLVLMFDMKEEIEVDPQFIAQLMEQLDVFISIKP--- 386
Query: 1217 EEAKAPSRGFVVRDAPWTASSSEKA 1241
+ K PS+ +V+ A + +A
Sbjct: 387 -KPKQPSKSVIVKSVERNALNMYEA 410
Score = 59.3 bits (142), Expect = 2e-08
Identities = 54/274 (19%), Positives = 120/274 (43%), Gaps = 25/274 (9%)
Query: 247 EIMQETGTRINIPPP------SVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAV 300
+IM+ET T+I P S I +G+KE + +A I + + K + T + +
Sbjct: 79 KIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVT-LKM 137
Query: 301 EVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSD-----SISETVILRGEPEKLGQALT 355
+V ++H +VIG GN++++++E TG + P S+ S V + G+P + A
Sbjct: 138 DVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARV 197
Query: 356 EVYAKANSFTVSSVAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFTEGE----DKITLE 411
+ + + L + ++ I+Q + + F + + +
Sbjct: 198 RIRELLPLVLMFELPIAGILQP-VPDPNSPSIQHISQTY-NISVSFKQRSRMYGATVIVR 255
Query: 412 GPTEDVNVAQEQIEGMVKDLINRMD-----YVEINIDHKFHRHLIGKSGANINRIKDQYK 466
G + + +E +++ L + +++I + H ++G++G+NI I +
Sbjct: 256 GSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTG 315
Query: 467 VSVRIPPDS--EKSNLIRIEGDPQGVQQAKRELL 498
+ P S +K + + ++G + V A++ L+
Sbjct: 316 AQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLM 349
Score = 58.9 bits (141), Expect = 3e-08
Identities = 68/284 (23%), Positives = 123/284 (43%), Gaps = 27/284 (9%)
Query: 598 GKGGANI-KKIREESNTKIDLP------AENSNSETIIITGKRANCEAARSRILSIQKDL 650
G+ G + +KI EE+NT+I P A++ I ++GK+ + + A+ I+S+
Sbjct: 70 GRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTK 129
Query: 651 ANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFP-----VEGSGSDTVVIRGP 705
+N +++ + H+ +IG G I+ +MEE G HIHFP + S+ V I G
Sbjct: 130 SNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEET-GCHIHFPDSNRNNQAEKSNQVSIAGQ 188
Query: 706 SSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPA 765
+ VE A+ ++ L + +P + I+ + + V F
Sbjct: 189 PAGVESARVRIRELLPLVLMFELPIAGILQP-----VPDPNSPSIQHISQTYNISVSFKQ 243
Query: 766 AEDKDQDLITIIGKED---AVREAQKE-LEALIQNLDNVVEDSMLVD--PKHHRHFVIRR 819
+ + G ++ AV+E LE L +L + + S +D +HH + R
Sbjct: 244 RSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRN 303
Query: 820 GQVLREIAEEYGGVMVSFPRSGTQSDKVT--LKGAKDCVEAAKK 861
G ++ I + G + FP K T L+G + V A++
Sbjct: 304 GSNIKHIMQR-TGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQ 346
Score = 58.2 bits (139), Expect = 5e-08
Identities = 57/269 (21%), Positives = 111/269 (41%), Gaps = 33/269 (12%)
Query: 469 VRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGE 528
++I S+K I++ G + V++AK ++ + N T + + H +IG+ G
Sbjct: 94 LKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGN 153
Query: 529 RIREIRDKFPEVIINFPD-----PAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYS 583
I+++ ++ I+FPD A+KS+ V + G VE ++++
Sbjct: 154 NIKKVMEE-TGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIREL---------- 202
Query: 584 ISVPIFKQFHKNIIG-------KGGANIKKIREESNTKIDLPAEN-SNSETIIITGKRAN 635
+P+ F I G +I+ I + N + + T+I+ G + N
Sbjct: 203 --LPLVLMFELPIAGILQPVPDPNSPSIQHISQTYNISVSFKQRSRMYGATVIVRGSQNN 260
Query: 636 CEAARSRILSIQKDLANI------AEVEVSIPAKLHNSLIGTKGRLIRSIMEECGG-VHI 688
A + + + LA ++ I A+ H ++G G I+ IM+ G +H
Sbjct: 261 TSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHF 320
Query: 689 HFPVEGSGSDTVVIRGPSSDVEKAKKQLL 717
P TV ++G V A++ L+
Sbjct: 321 PDPSNPQKKSTVYLQGTIESVCLARQYLM 349
Score = 54.7 bits (130), Expect = 6e-07
Identities = 61/247 (24%), Positives = 104/247 (42%), Gaps = 34/247 (13%)
Query: 127 IMVSGKLDAVMKARKDIVARLQTQAS-ATVAIPKEH--HRFVIGKNGEKLQDLELKTATK 183
I VSGK + V +A++ I++ L T+++ T+ + H H VIGK G ++ + +T
Sbjct: 106 IKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCH 165
Query: 184 IQIPRPD-----DPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVERLEVEKAFHPFIA 238
I P + + SNQ+ I G G+E AR R E L + F IA
Sbjct: 166 IHFPDSNRNNQAEKSNQVSIAGQPAGVESAR-----------VRIRELLPLVLMFELPIA 214
Query: 239 G-------PYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEK 291
G P + + I Q ++ S V + AV + E
Sbjct: 215 GILQPVPDPNSPSIQHISQTYNISVSFKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLEH 274
Query: 292 KKKTTTIAV------EVKKSQHKYVIGPKGNSLQEILERTGVSVEIP-PSD-SISETVIL 343
+ A+ ++ H +++G G++++ I++RTG + P PS+ TV L
Sbjct: 275 LAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYL 334
Query: 344 RGEPEKL 350
+G E +
Sbjct: 335 QGTIESV 341
Score = 51.2 bits (121), Expect = 6e-06
Identities = 35/126 (27%), Positives = 60/126 (47%), Gaps = 8/126 (6%)
Query: 1069 GRKGAVITQ-IRLEHDVNIQFPDK---DDGNQPQDQITITGYEKNTEAARDAILRIVGEL 1124
GR G Q I E + I +P K ++ I ++G +++ + A++ I+ ++
Sbjct: 70 GRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTK 129
Query: 1125 EQMVSEDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSG----APDPNCVTVTGLP 1180
V+ + + H H+ +IG G I+K+M+E I FP S A N V++ G P
Sbjct: 130 SNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKSNQVSIAGQP 189
Query: 1181 ENVEEA 1186
VE A
Sbjct: 190 AGVESA 195
Score = 41.2 bits (95), Expect = 0.006
Identities = 35/154 (22%), Positives = 67/154 (43%), Gaps = 20/154 (12%)
Query: 152 SATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQ--IKITGTKEGIEKAR 209
S + I +HH F++G+NG ++ + +T +I P P +P + + + GT E + AR
Sbjct: 286 STQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLAR 345
Query: 210 HEVL----LISAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNR 265
++ L+ K E +EV+ F + ++M++ I+I P
Sbjct: 346 QYLMGCLPLVLMFDMK---EEIEVDPQF-----------IAQLMEQLDVFISIKPKPKQP 391
Query: 266 TEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIA 299
++ V E+ A + +K + TIA
Sbjct: 392 SKSVIVKSVERNALNMYEARKCLLGLESSGVTIA 425
Score = 40.0 bits (92), Expect = 0.014
Identities = 76/367 (20%), Positives = 148/367 (40%), Gaps = 50/367 (13%)
Query: 319 QEILERTGVSVEIPPSDSISET------VILRGEPEKLGQA----LTEVYAKANSFTVSS 368
Q+I+E T + P I + + G+ E + +A ++ + K+N T+
Sbjct: 78 QKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKM 137
Query: 369 VAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEF--------TEGEDKITLEGPTEDVNVA 420
+ + H +IGK G N+ K+ ++ HI F E +++++ G V A
Sbjct: 138 DVSHTE-HSHVIGKGGNNIKKVMEE-TGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESA 195
Query: 421 QEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNL 480
+ +I ++L+ + E+ I + + + +I I Y +SV S
Sbjct: 196 RVRI----RELLPLVLMFELPI-AGILQPVPDPNSPSIQHISQTYNISVSFKQRSRMYGA 250
Query: 481 IRI----EGDPQGVQQAKRELLE-LASRMEN--ERTKDLIIEQRFHRTIIGQKGERIREI 533
I + + V++ LLE LA + + + L I + H ++G+ G I+ I
Sbjct: 251 TVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHI 310
Query: 534 RDKFPEVIINFPDPA--QKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQ 591
+ I+FPDP+ QK V L+G V +Y+ + ++ + + Q
Sbjct: 311 MQR-TGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLMGCLPLVLMFDMKEEIEVDPQ 369
Query: 592 FHKNIIGKGGANIKKIREESNTKIDL-PAENSNSETIIITG---KRANCEAARSRILSIQ 647
F I ++ E+ + I + P S+++I+ N AR +L ++
Sbjct: 370 F-----------IAQLMEQLDVFISIKPKPKQPSKSVIVKSVERNALNMYEARKCLLGLE 418
Query: 648 KDLANIA 654
IA
Sbjct: 419 SSGVTIA 425
>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
Length = 556
Score = 68.6 bits (166), Expect = 4e-11
Identities = 87/398 (21%), Positives = 153/398 (38%), Gaps = 67/398 (16%)
Query: 463 DQYKVSVRIPPDSEKSNLIRIEGDPQGVQQ---AKRELLELASRMENERTKD----LIIE 515
+ Y + PD E S+ PQ Q+ + RE R D +++
Sbjct: 146 ENYSFKISYIPDEEVSS----PSPPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVP 201
Query: 516 QRFHRTIIGQKGERIREIRDKFP---EVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQK 572
+F IIG++G I+ I + ++ A + + P+ E C ++
Sbjct: 202 TQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMILEI 261
Query: 573 MVADLVENSYSISVPIFKQFHKNI----IGKGGANIKKIREESNTKIDLPAENSNS---- 624
M + E + +P+ H + IGK G N+KKI E+ TKI + + S
Sbjct: 262 MQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNP 321
Query: 625 -ETIIITGKRANCEAARSRIL-----SIQKDLANIAE----------------------- 655
TI + G C +A I+ + + D+ +
Sbjct: 322 ERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSY 381
Query: 656 -----VEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGS--GSDTVVIRGPSSD 708
V + IP + ++IG KG I+ + G P EG V+I GP
Sbjct: 382 PEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEA 441
Query: 709 VEKAKKQLLHLAEE------KQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVI 762
KA+ ++ +E K+ IR +IGKGG + ++++ T A VI
Sbjct: 442 QFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVI 501
Query: 763 FPAAEDKDQD---LITIIGKEDAVREAQKELEALIQNL 797
P + D++ ++ IIG A + AQ+++ ++Q +
Sbjct: 502 VPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQV 539
Score = 55.1 bits (131), Expect = 4e-07
Identities = 82/388 (21%), Positives = 152/388 (39%), Gaps = 72/388 (18%)
Query: 155 VAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPS---NQIKITGTKEGIEKARHE 211
+ +P + +IGK G ++++ +T +++ I R ++ + I T EG +A
Sbjct: 198 ILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRM 257
Query: 212 VLLISAEQ--DKRAVERLEVEKAFHPFIAGPYNRLVGE-------IMQETGTRINIPPP- 261
+L I ++ + + E + ++ H + G RL+G+ I ETGT+I I
Sbjct: 258 ILEIMQKEADETKLAEEIPLKILAHNGLVG---RLIGKEGRNLKKIEHETGTKITISSLQ 314
Query: 262 --SVNRTEIVFT--GEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNS 317
S+ E T G E A A I K E + N
Sbjct: 315 DLSIYNPERTITVKGTVEACASAEIEIMKKLREAFE----------------------ND 352
Query: 318 LQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSVAAPSWLHR 377
+ + +G + P PE+ + ++ P+
Sbjct: 353 MLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQ---------------EIVNLFIPTQAVG 397
Query: 378 FIIGKKGQNLAKITQQM-PKVHIEFTEGED----KITLEGPTEDVNVAQEQIEGMVKD-- 430
IIGKKG ++ ++ + + I EG D + + GP E AQ +I G +K+
Sbjct: 398 AIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEEN 457
Query: 431 LINRMDYVE----INIDHKFHRHLIGKSGANINRIKDQYKVSVRIP----PDSEKSNLIR 482
N + V+ I + +IGK G +N +++ V +P PD + ++R
Sbjct: 458 FFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVR 517
Query: 483 IEGDPQGVQQAKRELLELASRMENERTK 510
I G Q A+R++ E+ +++ + K
Sbjct: 518 IIGHFFASQTAQRKIREIVQQVKQQEQK 545
Score = 47.8 bits (112), Expect = 7e-05
Identities = 73/298 (24%), Positives = 106/298 (35%), Gaps = 79/298 (26%)
Query: 96 GEGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATV 155
G E ++ LEIMQ+ E LA++ L I+ A +V RL
Sbjct: 250 GTSEACRMILEIMQKEAD--ETKLAEEIPLKIL----------AHNGLVGRL-------- 289
Query: 156 AIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDD-----PSNQIKITGTKEGIEKARH 210
IGK G L+ +E +T TKI I D P I + GT E A
Sbjct: 290 ----------IGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEI 339
Query: 211 EV---LLISAEQDKRAV-------ERLEVEKAFHPF-----------------------I 237
E+ L + E D AV L F PF I
Sbjct: 340 EIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAI 399
Query: 238 AGPYNRLVGEIMQETGTRINIPP---PSVNRTEIVFTGEKEQLAQAVARI------KKIY 288
G + ++ + G I I P P V+ ++ TG E +A RI + +
Sbjct: 400 IGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFF 459
Query: 289 EEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIP--PSDSISETVILR 344
K++ + V S VIG G ++ E+ T V +P + +E VI+R
Sbjct: 460 NPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVR 517
Score = 42.7 bits (99), Expect = 0.002
Identities = 39/171 (22%), Positives = 73/171 (42%), Gaps = 14/171 (8%)
Query: 656 VEVSIPAKLHNSLIGTKGRLIRSIMEECGG-VHIHFPVE-GSGSDTVVIRGPSSDVEKAK 713
+ + +P + ++IG +G I++I ++ V IH G+ V I +A
Sbjct: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEAC 255
Query: 714 KQLLHLA-----EEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAED 768
+ +L + E K + + I A LIGK G ++K+ TG ++ + +D
Sbjct: 256 RMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQD 315
Query: 769 ----KDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHF 815
+ IT+ G +A A+ E +++ L E+ ML H +F
Sbjct: 316 LSIYNPERTITVKGTVEACASAEIE---IMKKLREAFENDMLAVNTHSGYF 363
Score = 41.6 bits (96), Expect = 0.005
Identities = 33/121 (27%), Positives = 55/121 (45%), Gaps = 11/121 (9%)
Query: 1042 QAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQI 1101
QA Q D F L + V ++ IIG++G I I + + K++ + +
Sbjct: 188 QARQID-----FPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPV 242
Query: 1102 TITGYEKNTEAARDAILRIVGEL--EQMVSEDVPLDHRVH----ARIIGARGKAIRKIMD 1155
TI + T A IL I+ + E ++E++PL H R+IG G+ ++KI
Sbjct: 243 TIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEH 302
Query: 1156 E 1156
E
Sbjct: 303 E 303
Score = 41.2 bits (95), Expect = 0.006
Identities = 69/340 (20%), Positives = 136/340 (40%), Gaps = 67/340 (19%)
Query: 876 LECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGR 935
L +P +F +++G +G I+ IT+ ++ R+EN+ + +PV E
Sbjct: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDI-HRKENSGAAEKPVTIHATPE----- 249
Query: 936 EAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYVIGQKGSGI 995
G+ C +I+ +KE E K A E + +++ L +IG++G +
Sbjct: 250 -------GTSEACRMILEIMQKEADET-KLAEE----IPLKILAHNGLVGRLIGKEGRNL 297
Query: 996 RKMMDEFEVNIHVPAPELQS-------DIIAITGLAANLDRAKAGLLERVKELQAEQEDR 1048
+K+ E E + LQ I + G A+ ++++++E E +
Sbjct: 298 KKI--EHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREA-FENDML 354
Query: 1049 ALRSFK--------------------------LSVTVDPKYHPKIIGRKGAVITQIRLEH 1082
A+ + +++ + + IIG+KGA I Q+
Sbjct: 355 AVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFA 414
Query: 1083 DVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQM----VSEDVPLDHRV 1138
+I+ + + + + ITG EA A RI G+L++ E+V L+ +
Sbjct: 415 GASIKIAPAEGPDVSERMVIITG---PPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHI 471
Query: 1139 HA------RIIGARGKAIRKIMDEFKVDIRFPQSGAPDPN 1172
R+IG GK + ++ + ++ P+ PD N
Sbjct: 472 RVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDEN 511
Score = 33.1 bits (74), Expect = 1.7
Identities = 59/288 (20%), Positives = 114/288 (39%), Gaps = 63/288 (21%)
Query: 310 VIGPKGNSLQEILERTGVSVEI---PPSDSISETVILRGEPEKLGQA---LTEVYAKANS 363
+IG +G +++ I ++T V+I S + + V + PE +A + E+ K
Sbjct: 208 IIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMILEIMQKEAD 267
Query: 364 FTVSS------VAAPSWLHRFIIGKKGQNLAKITQQM-PKVHIEFTEG------EDKITL 410
T + + A + L +IGK+G+NL KI + K+ I + E IT+
Sbjct: 268 ETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITV 327
Query: 411 EGPTEDVNVAQEQIEGMVKDLINRMDYVEINI----------DHKF----HRH------- 449
+G E A+ +I +++ D + +N H+F H H
Sbjct: 328 KGTVEACASAEIEIMKKLREAFEN-DMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEI 386
Query: 450 ------------LIGKSGANINRIKDQYKVSVRIPP---DSEKSNLIRIEGDPQGVQQAK 494
+IGK GA+I ++ S++I P ++ I G P+ +A+
Sbjct: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
Query: 495 RELLELASRMENERTKDLIIEQRFHRT-------IIGQKGERIREIRD 535
+ K+ + + R +IG+ G+ + E+++
Sbjct: 447 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQN 494
>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
[Homo sapiens]
Length = 579
Score = 62.8 bits (151), Expect = 2e-09
Identities = 94/392 (23%), Positives = 163/392 (41%), Gaps = 69/392 (17%)
Query: 157 IPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDD---PSNQIKITGTKEGIEKARHEVL 213
+P + +IGK G ++++ +T +KI + R ++ I I T EG A +L
Sbjct: 202 VPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAACKSIL 261
Query: 214 LI--SAEQDKRAVERLEVEKAFHPFIAGPYNRLVG-------EIMQETGTRINIPP---- 260
I QD + E + ++ H G RL+G +I Q+T T+I I P
Sbjct: 262 EIMHKEAQDIKFTEEIPLKILAHNNFVG---RLIGKEGRNLKKIEQDTDTKITISPLQEL 318
Query: 261 --PSVNRTEIVFTGEKEQLAQAVARI-KKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNS 317
+ RT I G E A+A I KKI E + ++ + Q + G N+
Sbjct: 319 TLYNPERT-ITVKGNVETCAKAEEEIMKKIRESYENDIASMNL-----QAHLIPGLNLNA 372
Query: 318 LQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSV--AAPSWL 375
L +G +PP S G P A+T Y + +V P+
Sbjct: 373 LGLFPPTSG----MPPPTS--------GPP----SAMTPPYPQFEQSETETVHLFIPALS 416
Query: 376 HRFIIGKKGQNLAKITQ-QMPKVHIEFTEGED----KITLEGPTEDVNVAQEQIEGMVKD 430
IIGK+GQ++ ++++ + I E D + + GP E AQ +I G +K+
Sbjct: 417 VGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKE 476
Query: 431 LINRMDYVEINIDHKFHRHL----------IGKSGANINRIKDQYKVSVRIP----PDSE 476
++V + K H+ IGK G +N +++ V +P PD
Sbjct: 477 ----ENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDEN 532
Query: 477 KSNLIRIEGDPQGVQQAKRELLELASRMENER 508
+++I G Q A+R++ E+ ++++ +
Sbjct: 533 DQVVVKITGHFYACQVAQRKIQEILTQVKQHQ 564
Score = 61.2 bits (147), Expect = 6e-09
Identities = 76/358 (21%), Positives = 140/358 (39%), Gaps = 75/358 (20%)
Query: 512 LIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDP---AQKSDIVQLRGPKNEVEKCTK 568
L++ +F IIG++G IR I + I A + I L P+ C
Sbjct: 200 LLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAACKS 259
Query: 569 YMQKMVADLVENSYSISVPIFKQFHKN----IIGKGGANIKKIREESNTKIDL-PAEN-- 621
++ M + + ++ +P+ H N +IGK G N+KKI ++++TKI + P +
Sbjct: 260 ILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELT 319
Query: 622 --SNSETIIITGKRANCEAARSRIL-----SIQKDLANI--------------------- 653
+ TI + G C A I+ S + D+A++
Sbjct: 320 LYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPT 379
Query: 654 --------------------------AEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVH 687
V + IPA ++IG +G+ I+ + G
Sbjct: 380 SGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASI 439
Query: 688 IHFPVEGSGSDT--VVIRGPSSDVEKAKKQLLHLAEE------KQTKSFTVDIRAKPEYH 739
P E + V+I GP KA+ ++ +E K+ IR
Sbjct: 440 KIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAA 499
Query: 740 KFLIGKGGGKIRKVRDSTGARVIFP---AAEDKDQDLITIIGKEDAVREAQKELEALI 794
+IGKGG + ++++ + A V+ P ++ DQ ++ I G A + AQ++++ ++
Sbjct: 500 GRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQRKIQEIL 557
Score = 50.8 bits (120), Expect = 8e-06
Identities = 83/374 (22%), Positives = 150/374 (40%), Gaps = 64/374 (17%)
Query: 310 VIGPKGNSLQEILERTGVSVEIPPSDSIS---ETVILRGEPEKLGQALTEVY------AK 360
+IG +G +++ I ++T +++ ++ +++ + PE A + A+
Sbjct: 210 IIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAACKSILEIMHKEAQ 269
Query: 361 ANSFT----VSSVAAPSWLHRFIIGKKGQNLAKITQQM-------PKVHIEFTEGEDKIT 409
FT + +A +++ R +IGK+G+NL KI Q P + E IT
Sbjct: 270 DIKFTEEIPLKILAHNNFVGR-LIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTIT 328
Query: 410 LEGPTEDVNVAQEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSV 469
++G E A+E+I +++ D +N+ HLI G N+N + S
Sbjct: 329 VKGNVETCAKAEEEIMKKIRESYEN-DIASMNLQ----AHLI--PGLNLNALGLFPPTSG 381
Query: 470 RIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGER 529
PP S G P + + T L I IIG++G+
Sbjct: 382 MPPPTS---------GPPSAMTPPYPQF-----EQSETETVHLFIPALSVGAIIGKQGQH 427
Query: 530 IREIRDKFPEVIINFPD---PAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYS--- 583
I+++ +F I P K +V + GP K + + + EN S
Sbjct: 428 IKQL-SRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKE--ENFVSPKE 484
Query: 584 -------ISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSE----TIIITGK 632
I VP F +IGKGG + +++ S+ ++ +P + + E + ITG
Sbjct: 485 EVKLEAHIRVPSFAA--GRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGH 542
Query: 633 RANCEAARSRILSI 646
C+ A+ +I I
Sbjct: 543 FYACQVAQRKIQEI 556
Score = 48.1 bits (113), Expect = 5e-05
Identities = 45/171 (26%), Positives = 76/171 (44%), Gaps = 14/171 (8%)
Query: 1055 LSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAAR 1114
L + V ++ IIG++GA I I + I K++ + ITI + T AA
Sbjct: 198 LRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAAC 257
Query: 1115 DAILRIVGELEQMV--SEDVPLDHRVH----ARIIGARGKAIRKIMDEFKVDIRFPQSGA 1168
+IL I+ + Q + +E++PL H R+IG G+ ++KI E D + S
Sbjct: 258 KSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKI--EQDTDTKITISPL 315
Query: 1169 PD------PNCVTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKP 1213
+ +TV G E +A + I+ E + + S LQ ++ P
Sbjct: 316 QELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIP 366
Score = 34.7 bits (78), Expect = 0.59
Identities = 26/132 (19%), Positives = 62/132 (46%), Gaps = 17/132 (12%)
Query: 98 GEQAKICLEIMQRTGAHLELSLAKDQGLSI---MVSGKLDAVMKARKDIVARL------- 147
G+Q + ++ + GA ++++ A+ + +++G +A KA+ I ++
Sbjct: 422 GKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVS 481
Query: 148 ---QTQASATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQ----IKITG 200
+ + A + +P VIGK G+ + +L+ ++ ++ +PR P +KITG
Sbjct: 482 PKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITG 541
Query: 201 TKEGIEKARHEV 212
+ A+ ++
Sbjct: 542 HFYACQVAQRKI 553
Score = 33.9 bits (76), Expect = 1.0
Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 16/125 (12%)
Query: 1067 IIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGEL-- 1124
IIG++G I Q+ +I+ + + + ITG EA A RI G++
Sbjct: 420 IIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITG---PPEAQFKAQGRIYGKIKE 476
Query: 1125 EQMVS--EDVPLDHRVHA------RIIGARGKAIRKIMDEFKVDIRFPQSGAPDPN---C 1173
E VS E+V L+ + R+IG GK + ++ + ++ P+ PD N
Sbjct: 477 ENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVV 536
Query: 1174 VTVTG 1178
V +TG
Sbjct: 537 VKITG 541
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 61.6 bits (148), Expect = 5e-09
Identities = 73/342 (21%), Positives = 142/342 (41%), Gaps = 74/342 (21%)
Query: 450 LIGKSGANINRIKDQYKVSVRIPPDS----EKSNLIRIEGDPQGVQQAKRELLELASR-- 503
+IG+ G IN+I+ V+I PDS E+S + + G P+ VQ+AK L ++ SR
Sbjct: 159 IIGRGGEQINKIQQDSGCKVQISPDSGGLPERS--VSLTGAPESVQKAKMMLDDIVSRGR 216
Query: 504 -------------MENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQK 550
+N ++++I +IG+ GE I++++++ +I D +Q
Sbjct: 217 GGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN 276
Query: 551 SDI---VQLRGPKNEVEKCTKYMQKMVADLVENSY------------SISVPIFKQFHKN 595
+++ +++ G +V++ + + ++ + + + I VP+ +
Sbjct: 277 TNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGV 336
Query: 596 IIGKGGANIKKIREESNTKIDLPAENSNSETII--ITGKRANCEAARSRILSIQKDLAN- 652
+IG+ G IKKI+ ++ +I ++ I I G CE A I + + L +
Sbjct: 337 VIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSG 396
Query: 653 ---------------------------IAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGG 685
E+ SIP +IG G +++I ++ G
Sbjct: 397 PPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGA 456
Query: 686 ---VHIHFPVEGSGS-DTVVIRGPSSDVEKAKKQLLHLAEEK 723
+ P G + +IRG ++ AK+ L EEK
Sbjct: 457 FVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQ----LIEEK 494
Score = 43.9 bits (102), Expect = 0.001
Identities = 87/400 (21%), Positives = 149/400 (37%), Gaps = 97/400 (24%)
Query: 474 DSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREI 533
D +S + +GD Q S E R D ++ IIG+ GE+I +I
Sbjct: 116 DQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVG-----LIIGRGGEQINKI 170
Query: 534 R-DKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQF 592
+ D +V I+ V L G V+K KM+ D + + P QF
Sbjct: 171 QQDSGCKVQISPDSGGLPERSVSLTGAPESVQKA-----KMMLDDIVSRGRGGPP--GQF 223
Query: 593 HKN---------------------IIGKGGANIKKIREESNTKIDL---PAENSN-SETI 627
H N +IGKGG IK+++E + K+ L ++N+N + +
Sbjct: 224 HDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPL 283
Query: 628 IITGKRANCEAARSRILSI--QKDLANIAE-----------VEVSIPAKLHNSLIGTKGR 674
I G + A ++ I ++D + ++V +P +IG G
Sbjct: 284 RIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGE 343
Query: 675 LIRSIMEECGGVHIHFPV-EGSGSDTVV-IRGPSSDVEKAKKQLLHLAEEKQT------- 725
+I+ I + GV I F +G+G + + I GP E A + + L + ++
Sbjct: 344 MIKKIQND-AGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPG 402
Query: 726 ------------------------KSFTVDIRAKPEYHK--FLIGKGGGKIRKVRDSTGA 759
+F++ HK +IG+GG ++ + TGA
Sbjct: 403 GPGMPPGGRGRGRGQGNWGPPGGEMTFSIPT------HKCGLVIGRGGENVKAINQQTGA 456
Query: 760 RV----IFPAAEDKDQDLITIIGKEDAVREAQKELEALIQ 795
V P D + L I G + A++ +E I+
Sbjct: 457 FVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIE 496
Score = 41.2 bits (95), Expect = 0.006
Identities = 70/348 (20%), Positives = 130/348 (37%), Gaps = 74/348 (21%)
Query: 225 ERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRTE--IVFTGEKEQLAQAVA 282
E V I G + +I Q++G ++ I P S E + TG E + +A
Sbjct: 147 EEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKM 206
Query: 283 RIKKIYEEKK--------------KKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVS 328
+ I + + T + + + VIG G +++++ ER GV
Sbjct: 207 MLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVK 266
Query: 329 VEI----PPSDSISETVILRGEPEKLGQALTEV-----------YAKANSFTVS-----S 368
+ + + ++ + + + G+P K+ QA V + N +
Sbjct: 267 MILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGID 326
Query: 369 VAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFTE----GEDKIT-LEGPTEDVNVAQEQ 423
V P +IG+ G+ + KI Q V I+F + G +KI + GP + A
Sbjct: 327 VPVPRHSVGVVIGRSGEMIKKI-QNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385
Query: 424 IEGMVKDLINRMDYV-------------------------EINIDHKFHR--HLIGKSGA 456
I +++ L + E+ H+ +IG+ G
Sbjct: 386 INDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGE 445
Query: 457 NINRIKDQ----YKVSVRIPPDSEKS-NLIRIEGDPQGVQQAKRELLE 499
N+ I Q ++S ++PP+ + + L I G PQ + AK+ + E
Sbjct: 446 NVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEE 493
Score = 39.7 bits (91), Expect = 0.018
Identities = 50/238 (21%), Positives = 91/238 (38%), Gaps = 24/238 (10%)
Query: 973 VTIEVEVPFDLHRYVIGQKGSGIRKMMDEF--EVNIHVPAPELQSDIIAITGLAANLDRA 1030
+T E VP + +IG+ G I K+ + +V I + L +++TG ++ +A
Sbjct: 145 MTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKA 204
Query: 1031 KAGLLERVKELQA-------EQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHD 1083
K L + V + + + + + +IG+ G I Q++
Sbjct: 205 KMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAG 264
Query: 1084 VN-IQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQMV-------------S 1129
V I D + I G + A + ++ I+ E +Q
Sbjct: 265 VKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGG 324
Query: 1130 EDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVT-VTGLPENVEEA 1186
DVP+ +IG G+ I+KI ++ V I+F Q P + + G P+ E A
Sbjct: 325 IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHA 382
Score = 38.1 bits (87), Expect = 0.054
Identities = 46/217 (21%), Positives = 94/217 (43%), Gaps = 36/217 (16%)
Query: 727 SFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARV-IFPAAEDKDQDLITIIGKEDAVRE 785
S T + R +IG+GG +I K++ +G +V I P + + +++ G ++V++
Sbjct: 144 SMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQK 203
Query: 786 AQKELEALI---------QNLDN-------VVEDSMLVDPKHHRHFVIRRGQVLREIAEE 829
A+ L+ ++ Q DN V++ M+ P VI +G + +E
Sbjct: 204 AKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMI--PAGKAGLVIGKGGETIKQLQE 261
Query: 830 YGGVMVSFPRSGTQSDKV----TLKGAKDCVEAAKKRIQEIIEDLE-------------A 872
GV + + G+Q+ V + G V+ A + + +I+ + +
Sbjct: 262 RAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRI 321
Query: 873 QVTLECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKF 909
++ +P+ V+G G I++I D V+I+F
Sbjct: 322 GGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQF 358
Score = 35.8 bits (81), Expect = 0.27
Identities = 47/268 (17%), Positives = 97/268 (36%), Gaps = 37/268 (13%)
Query: 122 DQGLSIMVSGKLDAVMKARKDIVARLQTQASATVAIPKEHHRFVIGKNGEKLQDLELKTA 181
DQ S ++ + D++ I +T + +P +IG+ GE++ ++ +
Sbjct: 116 DQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSG 175
Query: 182 TKIQIPRPDD---PSNQIKITGTKEGIEKARHEVLLISAE---------------QDKRA 223
K+QI PD P + +TG E ++KA+ + I +
Sbjct: 176 CKVQI-SPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGT 234
Query: 224 VERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRTEI----VFTGEKEQLAQ 279
V+ + + + G + ++ + G ++ + T + G+ ++ Q
Sbjct: 235 VQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQ 294
Query: 280 AVARIKKIYEEK------------KKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGV 327
A + I E+ + I V V + VIG G +++I GV
Sbjct: 295 ACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGV 354
Query: 328 SVEIPPSDSISETVI--LRGEPEKLGQA 353
++ D I + G P++ A
Sbjct: 355 RIQFKQDDGTGPEKIAHIMGPPDRCEHA 382
>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
isoform 1 [Homo sapiens]
Length = 577
Score = 60.1 bits (144), Expect = 1e-08
Identities = 83/359 (23%), Positives = 142/359 (39%), Gaps = 77/359 (21%)
Query: 512 LIIEQRFHRTIIGQKGERIREIRDKFPEVI-INFPDPAQKSD--IVQLRGPKNEVEKCTK 568
L++ ++ IIG++G IR I + I ++ + A ++ I P+ C
Sbjct: 200 LLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKM 259
Query: 569 YMQKMVADLVENSYSISVPIFKQFHKN----IIGKGGANIKKIREESNTKI------DLP 618
++ M + + + VP+ H N +IGK G N+KK+ +++ TKI DL
Sbjct: 260 ILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLT 319
Query: 619 AENSNSETIIITGKRANCEAARSRI--------------LSIQKDL---ANIAE------ 655
N TI + G NC A I +S+Q L N+A
Sbjct: 320 LYNP-ERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPA 378
Query: 656 -----------------------------VEVSIPAKLHNSLIGTKGRLIRSIMEECGGV 686
V+V IPA+ ++IG KG+ I+ +
Sbjct: 379 SSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASAS 438
Query: 687 HIHFPVEGSGSDT--VVIRGPSSDVEKAKKQLLHLAEE------KQTKSFTVDIRAKPEY 738
P E S V+I GP KA+ ++ +E K+ IR
Sbjct: 439 IKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASA 498
Query: 739 HKFLIGKGGGKIRKVRDSTGARVIFP---AAEDKDQDLITIIGKEDAVREAQKELEALI 794
+IGKGG + ++++ T A V+ P ++ DQ ++ IIG A + AQ+++ ++
Sbjct: 499 AGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDIL 557
Score = 58.2 bits (139), Expect = 5e-08
Identities = 87/394 (22%), Positives = 162/394 (41%), Gaps = 51/394 (12%)
Query: 148 QTQASATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDD---PSNQIKITGTKEG 204
Q + +P ++ +IGK G ++++ +T +KI + R ++ I + T EG
Sbjct: 193 QVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEG 252
Query: 205 IEKARHEVLLI---SAEQDKRAVE---RLEVEKAFHPFIAGPYNRLVGEIMQETGTRINI 258
A +L I A+ K A E ++ F + G R + ++ Q+T T+I I
Sbjct: 253 CSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITI 312
Query: 259 PP------PSVNRTEIVFTGEKEQLAQAVARI-KKIYEEKKKKTTTIAVEVKKSQHKYVI 311
+ RT I G E +A I KK+ E + ++++ ++I
Sbjct: 313 SSLQDLTLYNPERT-ITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQ------SHLI 365
Query: 312 GPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSVAA 371
P N L S PP S++ G A + +A + V
Sbjct: 366 -PGLNLAAVGLFPASSSAVPPPPSSVT------------GAAPYSSFMQAPEQEMVQVFI 412
Query: 372 PSWLHRFIIGKKGQNLAKITQ-QMPKVHIEFTEGEDK----ITLEGPTEDVNVAQEQIEG 426
P+ IIGKKGQ++ ++++ + I E D + + GP E AQ +I G
Sbjct: 413 PAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYG 472
Query: 427 MVKD--LINRMDYVE----INIDHKFHRHLIGKSGANINRIKDQYKVSVRIP----PDSE 476
+K+ + V+ I + +IGK G +N +++ V +P PD
Sbjct: 473 KLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDEN 532
Query: 477 KSNLIRIEGDPQGVQQAKRELLELASRMENERTK 510
+++I G Q A+R++ ++ ++++ + K
Sbjct: 533 DQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQK 566
Score = 47.0 bits (110), Expect = 1e-04
Identities = 53/218 (24%), Positives = 89/218 (40%), Gaps = 26/218 (11%)
Query: 1055 LSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAAR 1114
L + V +Y IIG++GA I I + I K++ + I++ + +A
Sbjct: 198 LRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSAC 257
Query: 1115 DAILRIVGE--LEQMVSEDVPLDHRVH----ARIIGARGKAIRKIMDEFKVDIRFPQSGA 1168
IL I+ + + +++VPL H R+IG G+ ++K+ + + I S
Sbjct: 258 KMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITI--SSL 315
Query: 1169 PD------PNCVTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKP--------- 1213
D +TV G EN A I+ E + V + +LQ ++ P
Sbjct: 316 QDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGL 375
Query: 1214 -PAHEEAKAPSRGFVVRDAPWTASSSEKAPDMSSSEEF 1250
PA A P V AP+ SS +AP+ + F
Sbjct: 376 FPASSSAVPPPPSSVTGAAPY--SSFMQAPEQEMVQVF 411
Score = 40.0 bits (92), Expect = 0.014
Identities = 73/363 (20%), Positives = 135/363 (37%), Gaps = 84/363 (23%)
Query: 871 EAQVTLECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQENGDE 930
+ + L +P ++ +++G +G+ I+ IT+ +I VH +EN
Sbjct: 193 QVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKID--------VHR-----KENAGA 239
Query: 931 AGEGREAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYVIGQ 990
A + G C +I+ KE AK+ A V +++ + +IG+
Sbjct: 240 AEKAISVHSTPEGCSSACKMILEIMHKE----AKDTKTA-DEVPLKILAHNNFVGRLIGK 294
Query: 991 KGSGIRKMMDEFEVNIHVPAPE-----LQSDIIAITGLAANLDRAKAGLLERVKELQAEQ 1045
+G ++K+ + E I + + + I + G N RA+ ++++V+E A +
Sbjct: 295 EGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVRE--AYE 352
Query: 1046 EDRALRSFKL--------------------------SVTVDPKYHP-------------- 1065
D A S + SVT Y
Sbjct: 353 NDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFI 412
Query: 1066 ------KIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILR 1119
IIG+KG I Q+ +I+ + + + ITG EA A R
Sbjct: 413 PAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG---PPEAQFKAQGR 469
Query: 1120 IVGELEQM----VSEDVPLDHRVHA------RIIGARGKAIRKIMDEFKVDIRFPQSGAP 1169
I G+L++ E+V L+ + R+IG GK + ++ + ++ P+ P
Sbjct: 470 IYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTP 529
Query: 1170 DPN 1172
D N
Sbjct: 530 DEN 532
Score = 33.5 bits (75), Expect = 1.3
Identities = 24/106 (22%), Positives = 48/106 (45%), Gaps = 14/106 (13%)
Query: 127 IMVSGKLDAVMKARKDIVARL----------QTQASATVAIPKEHHRFVIGKNGEKLQDL 176
++++G +A KA+ I +L + + + +P VIGK G+ + +L
Sbjct: 454 VIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNEL 513
Query: 177 ELKTATKIQIPRPDDPSNQ----IKITGTKEGIEKARHEVLLISAE 218
+ TA ++ +PR P +KI G + A+ ++ I A+
Sbjct: 514 QNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQ 559
Score = 30.8 bits (68), Expect = 8.6
Identities = 29/156 (18%), Positives = 68/156 (43%), Gaps = 5/156 (3%)
Query: 975 IEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSD---IIAITGLAANLDRAK 1031
++V +P +IG+KG I+++ +I + PE ++ ITG +A+
Sbjct: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
Query: 1032 AGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFP-D 1090
+ ++KE ++ + + V ++IG+ G + +++ + P D
Sbjct: 468 GRIYGKLKEENFFGPKEEVK-LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRD 526
Query: 1091 KDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQ 1126
+ Q + I G+ ++ A+ I I+ +++Q
Sbjct: 527 QTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQ 562
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 59.7 bits (143), Expect = 2e-08
Identities = 84/354 (23%), Positives = 141/354 (39%), Gaps = 76/354 (21%)
Query: 360 KANSFTVSSVAAPSWLHRFIIGKKGQNLAKITQQMP-KVHIEFTEG---EDKITLEGPTE 415
++ S P + FIIG+ G+ +++I Q+ K+ I G E L G E
Sbjct: 96 QSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPE 155
Query: 416 DVNVAQEQIEGMVKDLINRMDY----------VEINIDHKFHRHLIGKSGANINRIKDQY 465
V A+ ++ +V+ + EI I +IGK G I +++++
Sbjct: 156 SVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERA 215
Query: 466 KVSVRI----PPDSEKSNLIRIEGDPQGVQQAKRELLEL--------------ASRMENE 507
V + + P ++ +RI GDP VQQAK +LEL SR+
Sbjct: 216 GVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGN 275
Query: 508 RTKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSD-IVQLRGPKNEVEKC 566
D+ I + +IG+ GE I++I++ I PD + I Q+ GP ++C
Sbjct: 276 EGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPP---DRC 332
Query: 567 TKYMQKMVADLVEN--------------------------------SYSISVPIFKQFHK 594
++ +++ DL+ + ++ VP K
Sbjct: 333 -QHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKT--G 389
Query: 595 NIIGKGGANIKKIREESNTKIDL-----PAENSNSETIIITGKRANCEAARSRI 643
IIGKGG IK I ++S +I+L P + N + I G + AR I
Sbjct: 390 LIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLI 443
Score = 59.7 bits (143), Expect = 2e-08
Identities = 64/295 (21%), Positives = 123/295 (41%), Gaps = 62/295 (21%)
Query: 450 LIGKSGANINRIKDQYKVSVRIPPDS----EKSNLIRIEGDPQGVQQAKRELLELASRME 505
+IG+ G I+RI+ + ++I PDS E+S ++ G P+ VQ AKR L ++ +
Sbjct: 115 IIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLT--GTPESVQSAKRLLDQIVEKGR 172
Query: 506 -----------NERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDI- 553
++++I +IG+ GE I++++++ ++ D Q +
Sbjct: 173 PAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGAD 232
Query: 554 --VQLRGPKNEVEKCTKYMQKMVADL-----VENSYS--------ISVPIFKQFHKNIIG 598
+++ G +V++ + + +++ D V N Y I VPI + +IG
Sbjct: 233 KPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIG 292
Query: 599 KGGANIKKIREESNTKIDL-PAENSNSETII-ITGKRANCEAARSRILSIQKDL------ 650
+ G IKKI+ ++ +I P + + E I ITG C+ A I + + +
Sbjct: 293 RNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPG 352
Query: 651 ---------------------ANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECG 684
+ E +P +IG G I+SI ++ G
Sbjct: 353 GPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSG 407
Score = 52.0 bits (123), Expect = 4e-06
Identities = 53/232 (22%), Positives = 102/232 (43%), Gaps = 30/232 (12%)
Query: 596 IIGKGGANIKKIREESNTKIDLPAENSN--SETIIITGKRANCEAARSRILSIQK----- 648
IIG+GG I +I++ES KI + ++ + ++TG + ++A+ + I +
Sbjct: 115 IIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPA 174
Query: 649 ------DLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECG--GVHIHFPVEGSGSDTV 700
D A E+ IPA +IG G I+ + E G V I + +G+D
Sbjct: 175 PGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKP 234
Query: 701 V-IRGPSSDVEKAKKQLLHLAEE-------------KQTKSFTVDIRAKPEYHKFLIGKG 746
+ I G V++AK+ +L L + + + +D+ +IG+
Sbjct: 235 LRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRN 294
Query: 747 GGKIRKVRDSTGARVIF-PAAEDKDQDLITIIGKEDAVREAQKELEALIQNL 797
G I+K+++ G R+ F P + + I G D + A + + L++++
Sbjct: 295 GEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSV 346
Score = 49.3 bits (116), Expect = 2e-05
Identities = 54/243 (22%), Positives = 101/243 (41%), Gaps = 23/243 (9%)
Query: 973 VTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPE---LQSDIIAITGLAANLDR 1029
+T E +VP + ++IG+ G I ++ E I + AP+ L +TG ++
Sbjct: 101 MTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQI-APDSGGLPERSCMLTGTPESVQS 159
Query: 1030 AKAGL---LERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNI 1086
AK L +E+ + + + + +IG+ G I Q++ V +
Sbjct: 160 AKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKM 219
Query: 1087 QFPDKDDGNQPQDQ-ITITGYEKNTEAARDAILRIV---GELEQMVSE-----------D 1131
N D+ + ITG + A++ +L ++ G ++ +E D
Sbjct: 220 VMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGID 279
Query: 1132 VPLDHRVHARIIGARGKAIRKIMDEFKVDIRF-PQSGAPDPNCVTVTGLPENVEEAIDHI 1190
VP+ +IG G+ I+KI ++ V I+F P G +TG P+ + A + I
Sbjct: 280 VPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEII 339
Query: 1191 LNL 1193
+L
Sbjct: 340 TDL 342
Score = 46.2 bits (108), Expect = 2e-04
Identities = 50/229 (21%), Positives = 103/229 (44%), Gaps = 34/229 (14%)
Query: 715 QLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARV-IFPAAEDKDQDL 773
QL + +++ T + + F+IG+GG +I +++ +G ++ I P + +
Sbjct: 88 QLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERS 147
Query: 774 ITIIGKEDAVREAQKELEALIQ------------NLDNVVEDSMLVDPKHHRHFVI-RRG 820
+ G ++V+ A++ L+ +++ N V++ M+ P VI + G
Sbjct: 148 CMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMI--PASKAGLVIGKGG 205
Query: 821 QVLREIAEEYG--GVMVSFPRSGTQSDK-VTLKGAKDCVEAAKKRIQEIIED-------- 869
+ ++++ E G VM+ T +DK + + G V+ AK+ + E+I D
Sbjct: 206 ETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVR 265
Query: 870 ------LEAQVTLECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKF-PD 911
+ ++ IP+ V+G G I++I D V+I+F PD
Sbjct: 266 NEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPD 314
Score = 42.4 bits (98), Expect = 0.003
Identities = 64/341 (18%), Positives = 122/341 (35%), Gaps = 73/341 (21%)
Query: 164 FVIGKNGEKLQDLELKTATKIQIPRPDD---PSNQIKITGTKEGIEKARHEVLLI----- 215
F+IG+ GE++ ++ ++ KIQI PD P +TGT E ++ A+ + I
Sbjct: 114 FIIGRGGEQISRIQQESGCKIQI-APDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGR 172
Query: 216 ------SAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRT--- 266
+ AV+ + + + + G + ++ + G ++ + T
Sbjct: 173 PAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGAD 232
Query: 267 -EIVFTGEKEQLAQA-------------VARIKKIYEEKKKKTTTIAVEVKKSQHKYVIG 312
+ TG+ ++ QA ++ Y + I V + + VIG
Sbjct: 233 KPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIG 292
Query: 313 PKGNSLQEILERTGVSVEIPPSDSISETVI--LRGEPEKLGQALTEVYAKANSFTVSSVA 370
G +++I GV ++ P D + I + G P++ A + S +
Sbjct: 293 RNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPG 352
Query: 371 AP------------SW-------LHRF-----------IIGKKGQNLAKITQQMPKVHIE 400
P +W L F IIGK G+ + I+QQ IE
Sbjct: 353 GPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQ-SGARIE 411
Query: 401 FTEGEDK--------ITLEGPTEDVNVAQEQIEGMVKDLIN 433
T+ G + ++ A++ IE + +N
Sbjct: 412 LQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVN 452
Score = 37.0 bits (84), Expect = 0.12
Identities = 68/364 (18%), Positives = 133/364 (36%), Gaps = 81/364 (22%)
Query: 63 AWGNKIRPI----KASVITQVFHVPLEERKYKDMNQFGEGEQAKICLEIMQRTGAHLELS 118
++G ++ P+ SV+T+ + VP M F G + I Q +G +++
Sbjct: 84 SFGTQLPPMHQQQSRSVMTEEYKVP------DGMVGFIIGRGGEQISRIQQESGCKIQI- 136
Query: 119 LAKDQG----LSIMVSGKLDAVMKARK---DIVARLQT-----------QASATVAIPKE 160
A D G S M++G ++V A++ IV + + A + IP
Sbjct: 137 -APDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPAS 195
Query: 161 HHRFVIGKNGEKLQDLELKTATKIQI----PRPDDPSNQIKITGTKEGIEKARHEVLLIS 216
VIGK GE ++ L+ + K+ + P+ ++ITG +++A+ VL +
Sbjct: 196 KAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELI 255
Query: 217 AEQDKRAVERLE--------------VEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPS 262
+Q R E + + + G ++ +I + G RI P
Sbjct: 256 RDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDD 315
Query: 263 VNRTEIV--FTGEKEQLAQAVARIKKIYEEKKKKT------------------------- 295
E + TG ++ A I + +
Sbjct: 316 GTTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGG 375
Query: 296 -TTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEI-----PPSDSISETVILRGEPEK 349
V + +IG G +++ I +++G +E+ P +D + +RG P++
Sbjct: 376 LQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQ 435
Query: 350 LGQA 353
+ A
Sbjct: 436 IDYA 439
>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
isoform a [Homo sapiens]
Length = 599
Score = 58.2 bits (139), Expect = 5e-08
Identities = 90/400 (22%), Positives = 163/400 (40%), Gaps = 53/400 (13%)
Query: 155 VAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPS---NQIKITGTKEGIEKARHE 211
+ +P + +IGK G ++++ +T +++ I R ++ + I T EG +A
Sbjct: 198 ILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRM 257
Query: 212 VLLISAEQ--DKRAVERLEVEKAFHPFIAGPYNRLVGE-------IMQETGTRINIPPP- 261
+L I ++ + + E + ++ H + G RL+G+ I ETGT+I I
Sbjct: 258 ILEIMQKEADETKLAEEIPLKILAHNGLVG---RLIGKEGRNLKKIEHETGTKITISSLQ 314
Query: 262 --SVNRTEIVFT--GEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNS 317
S+ E T G E A A I K E + +AV Q + G ++
Sbjct: 315 DLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDM-LAVN---QQANLIPGLNLSA 370
Query: 318 LQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSF------------T 365
L + TG+SV PP+ P + F
Sbjct: 371 LG--IFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQE 428
Query: 366 VSSVAAPSWLHRFIIGKKGQNLAKITQQM-PKVHIEFTEGED----KITLEGPTEDVNVA 420
+ ++ P+ IIGKKG ++ ++ + + I EG D + + GP E A
Sbjct: 429 IVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKA 488
Query: 421 QEQIEGMVKD--LINRMDYVE----INIDHKFHRHLIGKSGANINRIKDQYKVSVRIP-- 472
Q +I G +K+ N + V+ I + +IGK G +N +++ V +P
Sbjct: 489 QGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRD 548
Query: 473 --PDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTK 510
PD + ++RI G Q A+R++ E+ +++ + K
Sbjct: 549 QTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQK 588
Score = 50.8 bits (120), Expect = 8e-06
Identities = 40/153 (26%), Positives = 70/153 (45%), Gaps = 11/153 (7%)
Query: 656 VEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGS--GSDTVVIRGPSSDVEKAK 713
V + IP + ++IG KG I+ + G P EG V+I GP KA+
Sbjct: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
Query: 714 KQLLHLAEE------KQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAE 767
++ +E K+ IR +IGKGG + ++++ T A VI P +
Sbjct: 490 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQ 549
Query: 768 DKDQD---LITIIGKEDAVREAQKELEALIQNL 797
D++ ++ IIG A + AQ+++ ++Q +
Sbjct: 550 TPDENEEVIVRIIGHFFASQTAQRKIREIVQQV 582
Score = 44.3 bits (103), Expect = 8e-04
Identities = 90/449 (20%), Positives = 167/449 (37%), Gaps = 47/449 (10%)
Query: 463 DQYKVSVRIPPDSEKSNLIRIEGDPQGVQQ---AKRELLELASRMENERTKD----LIIE 515
+ Y + PD E S+ PQ Q+ + RE R D +++
Sbjct: 146 ENYSFKISYIPDEEVSS----PSPPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVP 201
Query: 516 QRFHRTIIGQKGERIREIRDKFP---EVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQK 572
+F IIG++G I+ I + ++ A + + P+ E C ++
Sbjct: 202 TQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMILEI 261
Query: 573 MVADLVENSYSISVPIFKQFHKNI----IGKGGANIKKIREESNTKIDLPAENSNS---- 624
M + E + +P+ H + IGK G N+KKI E+ TKI + + S
Sbjct: 262 MQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNP 321
Query: 625 -ETIIITGKRANCEAARSRIL-----SIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRS 678
TI + G C +A I+ + + D+ + + IP L+ S +G +
Sbjct: 322 ERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIPG-LNLSALGIFSTGLSV 380
Query: 679 IMEECG--GVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKP 736
+ G G P + + + H E++ + + +A
Sbjct: 381 LSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVG 440
Query: 737 EYHKFLIGKGGGKIRKVRDSTGARVIFPAAE--DKDQDLITIIGKEDAVREAQKEL---- 790
+IGK G I+++ GA + AE D + ++ I G +A +AQ +
Sbjct: 441 A----IIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKL 496
Query: 791 --EALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSDK-- 846
E + V ++ + P VI +G + V PR T +
Sbjct: 497 KEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEE 556
Query: 847 --VTLKGAKDCVEAAKKRIQEIIEDLEAQ 873
V + G + A+++I+EI++ ++ Q
Sbjct: 557 VIVRIIGHFFASQTAQRKIREIVQQVKQQ 585
Score = 43.9 bits (102), Expect = 0.001
Identities = 82/364 (22%), Positives = 135/364 (37%), Gaps = 59/364 (16%)
Query: 96 GEGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATV 155
G E ++ LEIMQ+ E LA++ L I+ A +V RL
Sbjct: 250 GTSEACRMILEIMQKEAD--ETKLAEEIPLKIL----------AHNGLVGRL-------- 289
Query: 156 AIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDD-----PSNQIKITGTKEGIEKARH 210
IGK G L+ +E +T TKI I D P I + GT E A
Sbjct: 290 ----------IGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEI 339
Query: 211 EV---LLISAEQDKRAV-ERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRT 266
E+ L + E D AV ++ + + G ++ + + G R PP +
Sbjct: 340 EIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLSPPAGPR-GAPPAAPYHP 398
Query: 267 EIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTG 326
+G L + + + + + +IG KG ++++ G
Sbjct: 399 FTTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAG 458
Query: 327 VSVEIPPSD--SISE-TVILRGEPEKLGQALTEVYAK---ANSFT-------VSSVAAPS 373
S++I P++ +SE VI+ G PE +A ++ K N F + + PS
Sbjct: 459 ASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPS 518
Query: 374 WLHRFIIGKKG------QNLAKITQQMPKVHIEFTEGEDKITLEGPTEDVNVAQEQIEGM 427
+IGK G QNL +P+ E + + G AQ +I +
Sbjct: 519 STAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREI 578
Query: 428 VKDL 431
V+ +
Sbjct: 579 VQQV 582
Score = 41.6 bits (96), Expect = 0.005
Identities = 33/121 (27%), Positives = 55/121 (45%), Gaps = 11/121 (9%)
Query: 1042 QAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQI 1101
QA Q D F L + V ++ IIG++G I I + + K++ + +
Sbjct: 188 QARQID-----FPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPV 242
Query: 1102 TITGYEKNTEAARDAILRIVGEL--EQMVSEDVPLDHRVH----ARIIGARGKAIRKIMD 1155
TI + T A IL I+ + E ++E++PL H R+IG G+ ++KI
Sbjct: 243 TIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEH 302
Query: 1156 E 1156
E
Sbjct: 303 E 303
Score = 37.7 bits (86), Expect = 0.070
Identities = 31/116 (26%), Positives = 53/116 (45%), Gaps = 13/116 (11%)
Query: 1067 IIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQ 1126
IIG+KGA I Q+ +I+ + + + + ITG EA A RI G+L++
Sbjct: 442 IIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITG---PPEAQFKAQGRIFGKLKE 498
Query: 1127 M----VSEDVPLDHRVHA------RIIGARGKAIRKIMDEFKVDIRFPQSGAPDPN 1172
E+V L+ + R+IG GK + ++ + ++ P+ PD N
Sbjct: 499 ENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDEN 554
>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
isoform 2 [Homo sapiens]
Length = 438
Score = 56.6 bits (135), Expect = 1e-07
Identities = 83/350 (23%), Positives = 133/350 (38%), Gaps = 88/350 (25%)
Query: 526 KGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSI- 584
K +R R+I+ I N P + + L VE C + + +V +YS
Sbjct: 76 KKQRSRKIQ------IRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETAVVNVTYSNR 129
Query: 585 -------SVPIFKQFHKN----IIGKGGANIKKIREESNTKI------DLPAENSNSETI 627
VP+ H N +IGK G N+KK+ +++ TKI DL N TI
Sbjct: 130 EQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNP-ERTI 188
Query: 628 IITGKRANCEAARSRI--------------LSIQKDL---ANIAE--------------- 655
+ G NC A I +S+Q L N+A
Sbjct: 189 TVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPP 248
Query: 656 --------------------VEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGS 695
V+V IPA+ ++IG KG+ I+ + P E
Sbjct: 249 SSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETP 308
Query: 696 GSDT--VVIRGPSSDVEKAKKQLLHLAEE------KQTKSFTVDIRAKPEYHKFLIGKGG 747
S V+I GP KA+ ++ +E K+ IR +IGKGG
Sbjct: 309 DSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGG 368
Query: 748 GKIRKVRDSTGARVIFP---AAEDKDQDLITIIGKEDAVREAQKELEALI 794
+ ++++ T A V+ P ++ DQ ++ IIG A + AQ+++ ++
Sbjct: 369 KTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDIL 418
Score = 43.1 bits (100), Expect = 0.002
Identities = 51/211 (24%), Positives = 83/211 (39%), Gaps = 32/211 (15%)
Query: 161 HHRFV---IGKNGEKLQDLELKTATKIQIPRPDD-----PSNQIKITGTKEGIEKARHEV 212
H+ FV IGK G L+ +E T TKI I D P I + G E +A E+
Sbjct: 145 HNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEI 204
Query: 213 LLISAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTG 272
+ E + V + ++ P + N + + + + PP SV TG
Sbjct: 205 MKKVREAYENDVAAMSLQSHLIPGL----NLAAVGLFPASSSAVPPPPSSV-------TG 253
Query: 273 EKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIP 332
A + + E++ + V + +IG KG ++++ S++I
Sbjct: 254 -----AAPYSSFMQAPEQE-----MVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIA 303
Query: 333 P---SDSISETVILRGEPEKLGQALTEVYAK 360
P DS VI+ G PE +A +Y K
Sbjct: 304 PPETPDSKVRMVIITGPPEAQFKAQGRIYGK 334
Score = 42.0 bits (97), Expect = 0.004
Identities = 76/343 (22%), Positives = 138/343 (40%), Gaps = 52/343 (15%)
Query: 200 GTKEGIEKARHE-------VLLISAEQDKRAVE---RLEVEKAFHPFIAGPYNRLVGEIM 249
GT E E+ E V + EQ ++A E ++ F + G R + ++
Sbjct: 105 GTVENCEQVNTESETAVVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVE 164
Query: 250 QETGTRINIPPP------SVNRTEIVFTGEKEQLAQAVARI-KKIYEEKKKKTTTIAVEV 302
Q+T T+I I + RT I G E +A I KK+ E + ++++
Sbjct: 165 QDTETKITISSLQDLTLYNPERT-ITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQ- 222
Query: 303 KKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKAN 362
++I P N L S PP S++ G A + +A
Sbjct: 223 -----SHLI-PGLNLAAVGLFPASSSAVPPPPSSVT------------GAAPYSSFMQAP 264
Query: 363 SFTVSSVAAPSWLHRFIIGKKGQNLAKITQ-QMPKVHIEFTEGEDK----ITLEGPTEDV 417
+ V P+ IIGKKGQ++ ++++ + I E D + + GP E
Sbjct: 265 EQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQ 324
Query: 418 NVAQEQIEGMVKD--LINRMDYVE----INIDHKFHRHLIGKSGANINRIKDQYKVSVRI 471
AQ +I G +K+ + V+ I + +IGK G +N +++ V +
Sbjct: 325 FKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVV 384
Query: 472 P----PDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTK 510
P PD +++I G Q A+R++ ++ ++++ + K
Sbjct: 385 PRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQK 427
Score = 35.0 bits (79), Expect = 0.46
Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 13/116 (11%)
Query: 1067 IIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQ 1126
IIG+KG I Q+ +I+ + + + ITG EA A RI G+L++
Sbjct: 281 IIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG---PPEAQFKAQGRIYGKLKE 337
Query: 1127 M----VSEDVPLDHRVHA------RIIGARGKAIRKIMDEFKVDIRFPQSGAPDPN 1172
E+V L+ + R+IG GK + ++ + ++ P+ PD N
Sbjct: 338 ENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDEN 393
Score = 34.7 bits (78), Expect = 0.59
Identities = 31/159 (19%), Positives = 64/159 (40%), Gaps = 14/159 (8%)
Query: 150 QASATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIK---ITGTKEGIE 206
Q V IP + +IGK G+ ++ L + I+I P+ P ++++ ITG E
Sbjct: 266 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQF 325
Query: 207 KARHEVL-------LISAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIP 259
KA+ + +++ + + V + + G + V E+ T + +P
Sbjct: 326 KAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVP 385
Query: 260 ----PPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKK 294
P ++ + G A +I+ I + K++
Sbjct: 386 RDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQ 424
Score = 33.5 bits (75), Expect = 1.3
Identities = 24/106 (22%), Positives = 48/106 (45%), Gaps = 14/106 (13%)
Query: 127 IMVSGKLDAVMKARKDIVARL----------QTQASATVAIPKEHHRFVIGKNGEKLQDL 176
++++G +A KA+ I +L + + + +P VIGK G+ + +L
Sbjct: 315 VIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNEL 374
Query: 177 ELKTATKIQIPRPDDPSNQ----IKITGTKEGIEKARHEVLLISAE 218
+ TA ++ +PR P +KI G + A+ ++ I A+
Sbjct: 375 QNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQ 420
Score = 30.8 bits (68), Expect = 8.6
Identities = 29/156 (18%), Positives = 68/156 (43%), Gaps = 5/156 (3%)
Query: 975 IEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSD---IIAITGLAANLDRAK 1031
++V +P +IG+KG I+++ +I + PE ++ ITG +A+
Sbjct: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
Query: 1032 AGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFP-D 1090
+ ++KE ++ + + V ++IG+ G + +++ + P D
Sbjct: 329 GRIYGKLKEENFFGPKEEVK-LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRD 387
Query: 1091 KDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQ 1126
+ Q + I G+ ++ A+ I I+ +++Q
Sbjct: 388 QTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQ 423
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 56.6 bits (135), Expect = 1e-07
Identities = 53/230 (23%), Positives = 96/230 (41%), Gaps = 31/230 (13%)
Query: 596 IIGKGGANIKKIREESNTKIDLPAENSN--SETIIITGKRANCEAARSRILSI------- 646
IIG+GG I +I+ ES KI + +E+S ++TG + E A+ + I
Sbjct: 92 IIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRNG 151
Query: 647 ---QKDL-ANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHF---PVEGSGSDT 699
D+ +N E+ IPA +IG G I+ + E G + P+
Sbjct: 152 PGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKP 211
Query: 700 VVIRGPSSDVEKAKKQLLHLAEEKQTKSF--------------TVDIRAKPEYHKFLIGK 745
+ I G + V++A++ +L + EK F ++++ +IG+
Sbjct: 212 LRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGR 271
Query: 746 GGGKIRKVRDSTGARVIF-PAAEDKDQDLITIIGKEDAVREAQKELEALI 794
G I+K+++ G R+ F P + ++G D + A + LI
Sbjct: 272 NGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHIISELI 321
Score = 55.8 bits (133), Expect = 2e-07
Identities = 69/343 (20%), Positives = 127/343 (37%), Gaps = 72/343 (20%)
Query: 157 IPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDD--PSNQIKITGTKEGIEKARHEVLL 214
+P + F+IG+ GE++ ++ ++ KIQI P +TGT E IE+A+ +
Sbjct: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQ 143
Query: 215 ISAE-----------QDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINI----P 259
I ++ + + + + G + ++ + TG ++ + P
Sbjct: 144 IVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGP 203
Query: 260 PPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTT--------------TIAVEVKKS 305
P+ + TG+ ++ QA + +I EK + +I V V +
Sbjct: 204 LPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRF 263
Query: 306 QHKYVIGPKGNSLQEILERTGVSVEIPPSDSIS--ETVILRGEPEKLGQA---------- 353
VIG G +++I GV ++ P D IS + G P++ A
Sbjct: 264 AVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHIISELILT 323
Query: 354 ---------LTEVYAKANSFTVSSVAAPSWLHRF-----------IIGKKGQNLAKITQQ 393
L + SV AP + +IGK G+N+ I QQ
Sbjct: 324 AQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQ 383
Query: 394 MPKVHIEFTEGED--------KITLEGPTEDVNVAQEQIEGMV 428
H+E + T+ G + + VA++ I+ V
Sbjct: 384 -SGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKV 425
Score = 50.4 bits (119), Expect = 1e-05
Identities = 68/342 (19%), Positives = 135/342 (39%), Gaps = 69/342 (20%)
Query: 439 EINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSE--KSNLIRIEGDPQGVQQAKRE 496
E + K +IG+ G I+RI+ + ++I +S + G P+ ++QAKR
Sbjct: 81 EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRL 140
Query: 497 LLELASRM-----------ENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFP 545
L ++ R N ++++I +IG+ GE I++++++ ++
Sbjct: 141 LGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQ 200
Query: 546 D---PAQKSDIVQLRGPKNEVEKCTKYMQKMVAD----------------LVENSYSISV 586
D P +++ G +V++ + + +++ + + S +SV
Sbjct: 201 DGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSV 260
Query: 587 PIFKQFHKNIIGKGGANIKKIREESNTKIDLPAEN--SNSETIIITGKRANCEAA----R 640
P F +IG+ G IKKI+ ++ +I ++ S + G C+ A
Sbjct: 261 PRFAV--GIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHIIS 318
Query: 641 SRILSIQK-----DLA------------------NIAEVEVSIPAKLHNSLIGTKGRLIR 677
IL+ Q+ LA + E+ ++PA +IG G I+
Sbjct: 319 ELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIK 378
Query: 678 SIMEECGGVHIHF-----PVEGSGSDTVVIRGPSSDVEKAKK 714
SI ++ G H+ P IRG +E A++
Sbjct: 379 SINQQ-SGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQ 419
Score = 48.5 bits (114), Expect = 4e-05
Identities = 55/244 (22%), Positives = 99/244 (40%), Gaps = 27/244 (11%)
Query: 973 VTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPE--LQSDIIAITGLAANLDRA 1030
+T E +VP + ++IG+ G I ++ E I + + + +TG ++++A
Sbjct: 78 ITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQA 137
Query: 1031 K---AGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQ 1087
K +++R + D S + + +IGR G I Q L+ ++
Sbjct: 138 KRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQ--LQERTGVK 195
Query: 1088 FPDKDDGNQP---QDQITITGYEKNTEAARDAILRIVGELEQMV---------------S 1129
DG P + ITG + AR+ +L I+ E +Q S
Sbjct: 196 MVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGS 255
Query: 1130 EDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRF-PQSGAPDPNCVTVTGLPENVEEAID 1188
+V + +IG G+ I+KI ++ V I+F P G V G P+ + A
Sbjct: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAA- 314
Query: 1189 HILN 1192
HI++
Sbjct: 315 HIIS 318
Score = 48.1 bits (113), Expect = 5e-05
Identities = 76/339 (22%), Positives = 127/339 (37%), Gaps = 69/339 (20%)
Query: 372 PSWLHRFIIGKKGQNLAKITQQMP-KVHIEFTEG---EDKITLEGPTEDVNVAQEQI--- 424
P + FIIG+ G+ +++I + K+ I E L G E + A+ +
Sbjct: 85 PDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQI 144
Query: 425 -------EGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSV------RI 471
G D+ + EI I +IG+ G I +++++ V + +
Sbjct: 145 VDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPL 204
Query: 472 PPDSEKSNLIRIEGDPQGVQQAKRELLELASRME-----------NERTKDLIIEQRFHR 520
P ++K +RI GD VQQA+ +LE+ + N R IE R
Sbjct: 205 PTGADKP--LRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPR 262
Query: 521 ----TIIGQKGERIREIRDKFPEVIINFPDPAQKSD-IVQLRGPKNEVEKCTKYMQKMVA 575
+IG+ GE I++I++ I PD + Q+ GP + + + +++
Sbjct: 263 FAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHIISELIL 322
Query: 576 DLVENS-----------------YSISVPIFKQFHKN---------IIGKGGANIKKIRE 609
E +S+ P Q +IGKGG NIK I +
Sbjct: 323 TAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQ 382
Query: 610 ESNTKIDL-----PAENSNSETIIITGKRANCEAARSRI 643
+S ++L P + N I G E AR I
Sbjct: 383 QSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLI 421
Score = 43.1 bits (100), Expect = 0.002
Identities = 67/299 (22%), Positives = 118/299 (39%), Gaps = 71/299 (23%)
Query: 952 IISGRKEKCEAAKEALEALVP----------------VTIEVEVPFDLHRYVIGQKGSGI 995
+++G E E AK L +V E+ +P VIG+ G I
Sbjct: 126 VLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETI 185
Query: 996 RKMMDEFEVNIHV----PAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQEDRALR 1051
+++ + V + + P P + ITG A + +A+ +LE ++E + + + R +R
Sbjct: 186 KQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIRE-KDQADFRGVR 244
Query: 1052 ----------SFKLSVTVDPKYHPKI-IGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQ 1100
S ++SV P++ I IGR G +I +I+ + V IQF DDG P+
Sbjct: 245 GDFNSRMGGGSIEVSV---PRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KPDDGISPERA 300
Query: 1101 ITITGYEKNTEAARDAILRIVGELE-----------------------------QMVSED 1131
+ G + A I ++ + Q ++
Sbjct: 301 AQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYT 360
Query: 1132 VPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAP--DPNC--VTVTGLPENVEEA 1186
VP D +IG G+ I+ I + + ++ P DPN T+ G+P+ +E A
Sbjct: 361 VPADK--CGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVA 417
Score = 41.6 bits (96), Expect = 0.005
Identities = 58/293 (19%), Positives = 117/293 (39%), Gaps = 56/293 (19%)
Query: 724 QTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARV-IFPAAEDKDQDLITIIGKEDA 782
Q T + + + F+IG+GG +I +++ +G ++ I + + + G ++
Sbjct: 74 QRTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPES 133
Query: 783 VREAQKELEALIQNL-----------DNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYG 831
+ +A++ L ++ N +L+ + R G+ ++++ E G
Sbjct: 134 IEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTG 193
Query: 832 --GVMVSFPRSGTQSDK-VTLKGAKDCVEAAKKRIQEIIE------------DLEAQV-- 874
VM+ T +DK + + G V+ A++ + EII D +++
Sbjct: 194 VKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGG 253
Query: 875 -TLECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKF-----------------PDREENA 916
++E ++P+ V+G G I++I D V+I+F PDR ++A
Sbjct: 254 GSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHA 313
Query: 917 VHSTEPVV---QEN------GDEAGEGREAKDCDPGSPRRCDIIIISGRKEKC 960
H ++ QE G GR D G+P I + +KC
Sbjct: 314 AHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKC 366
Score = 41.2 bits (95), Expect = 0.006
Identities = 53/249 (21%), Positives = 94/249 (37%), Gaps = 54/249 (21%)
Query: 155 VAIPKEHHRFVIGKNGEKLQDLELKTATKIQI----PRPDDPSNQIKITGTKEGIEKARH 210
+ IP VIG+ GE ++ L+ +T K+ + P P ++ITG +++AR
Sbjct: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
Query: 211 EVLLISAEQDK---RAVE------------RLEVEKAFHPFIAGPYNRLVGEIMQETGTR 255
VL I E+D+ R V + V + + G ++ +I + G R
Sbjct: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
Query: 256 INIPPP---SVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKK------------------ 294
I P S R V G ++ A I ++ +++
Sbjct: 287 IQFKPDDGISPERAAQVM-GPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGD 345
Query: 295 --------TTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEI-----PPSDSISETV 341
I V + VIG G +++ I +++G VE+ P SD
Sbjct: 346 WSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRF 405
Query: 342 ILRGEPEKL 350
+RG P+++
Sbjct: 406 TIRGVPQQI 414
Score = 38.1 bits (87), Expect = 0.054
Identities = 43/230 (18%), Positives = 91/230 (39%), Gaps = 38/230 (16%)
Query: 309 YVIGPKGNSLQEILERTGVSVEIPPSDS--ISETVILRGEPEKLGQA---LTEVYAKA-- 361
++IG G + I +G ++I S +L G PE + QA L ++ +
Sbjct: 91 FIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRN 150
Query: 362 ---------NSFTVSSVAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFTEG------ED 406
++ T+ + P+ +IG+ G+ + ++ ++ + +G +
Sbjct: 151 GPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADK 210
Query: 407 KITLEGPTEDVNVAQEQI------------EGMVKDLINRMD--YVEINIDHKFHRHLIG 452
+ + G V A+E + G+ D +RM +E+++ +IG
Sbjct: 211 PLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIG 270
Query: 453 KSGANINRIKDQYKVSVRIPPDS--EKSNLIRIEGDPQGVQQAKRELLEL 500
++G I +I++ V ++ PD ++ G P Q A + EL
Sbjct: 271 RNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHIISEL 320
Score = 37.7 bits (86), Expect = 0.070
Identities = 35/143 (24%), Positives = 65/143 (45%), Gaps = 8/143 (5%)
Query: 84 LEERKYKDMNQFGEGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDI 143
L+ER M +G + ++ TG ++ A++ L I+ R D
Sbjct: 188 LQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDF 247
Query: 144 VARLQTQASATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDD---PSNQIKITG 200
+R+ S V++P+ VIG+NGE ++ ++ +IQ +PDD P ++ G
Sbjct: 248 NSRMGG-GSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KPDDGISPERAAQVMG 305
Query: 201 TKEGIEKARH---EVLLISAEQD 220
+ + A H E++L + E+D
Sbjct: 306 PPDRCQHAAHIISELILTAQERD 328
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 55.5 bits (132), Expect = 3e-07
Identities = 43/151 (28%), Positives = 75/151 (49%), Gaps = 7/151 (4%)
Query: 579 ENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSE-TIIITGKRANCE 637
E+ I + + ++ K IIG+ GANIK++R+++ +ID+ E+ E ++I+G
Sbjct: 50 EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVC 109
Query: 638 AARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSG- 696
A++ I I + ++E ++S+P + +IG G IRSI + G I E G
Sbjct: 110 KAKAAIHQILTENTPVSE-QLSVPQRSVGRIIGRGGETIRSIC-KASGAKITCDKESEGT 167
Query: 697 ---SDTVVIRGPSSDVEKAKKQLLHLAEEKQ 724
S + I G +V AK +L E +
Sbjct: 168 LLLSRLIKISGTQKEVAAAKHLILEKVSEDE 198
Score = 45.8 bits (107), Expect = 3e-04
Identities = 38/157 (24%), Positives = 73/157 (46%), Gaps = 11/157 (7%)
Query: 973 VTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSD-IIAITGLAANLDRAK 1031
+ IE+ VP + + +IG++G+ I+++ + I V ++ + ++ I+G + +AK
Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
Query: 1032 AGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDK 1091
A + + + E E ++V + +IIGR G I I I +
Sbjct: 113 AAIHQILTENTPVSE---------QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKE 163
Query: 1092 DDGNQPQDQ-ITITGYEKNTEAARDAILRIVGELEQM 1127
+G + I I+G +K AA+ IL V E E++
Sbjct: 164 SEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEEL 200
Score = 45.4 bits (106), Expect = 3e-04
Identities = 43/182 (23%), Positives = 85/182 (46%), Gaps = 13/182 (7%)
Query: 710 EKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAEDK 769
E +++L + E+ +++R E K +IG+ G I+++R TGAR+ +
Sbjct: 39 ESREERLTFVGED----DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG 94
Query: 770 DQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEE 829
D+ ++ I G V +A+ + ++ + V + + V + + R G+ +R I +
Sbjct: 95 DERVLLISGFPVQVCKAKAAIHQILTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSICKA 153
Query: 830 YGGVMVSFPRS-GT--QSDKVTLKGAKDCVEAAKKRIQEII---EDLEAQV--TLECAIP 881
G + S GT S + + G + V AAK I E + E+L ++ + E +P
Sbjct: 154 SGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVP 213
Query: 882 QK 883
+K
Sbjct: 214 RK 215
Score = 42.4 bits (98), Expect = 0.003
Identities = 54/201 (26%), Positives = 81/201 (40%), Gaps = 14/201 (6%)
Query: 1067 IIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQ 1126
IIGR+GA I Q+R + I +D G++ + I+G+ A+ AI +I+ E
Sbjct: 67 IIGRQGANIKQLRKQTGARIDVDTEDVGDERV--LLISGFPVQVCKAKAAIHQILTE-NT 123
Query: 1127 MVSEDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPD---PNCVTVTGLPENV 1183
VSE + + R RIIG G+ IR I I + + ++G + V
Sbjct: 124 PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEV 183
Query: 1184 EEAIDHIL---NLEEEYLADVVDSEALQVYMKPP---AHEEAKAPSRGFVVRDAPWTASS 1237
A IL + +EE + S +V K P E+ P G A W +S
Sbjct: 184 AAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEP--GGAGEPALWKNTS 241
Query: 1238 SEKAPDMSSSEEFPSFGAQVA 1258
S P P G +A
Sbjct: 242 SSMEPTAPLVTPPPKGGGDMA 262
Score = 39.7 bits (91), Expect = 0.018
Identities = 32/132 (24%), Positives = 66/132 (50%), Gaps = 9/132 (6%)
Query: 98 GEQAKICLEIMQRTGAHLELSLAKDQGLS--IMVSGKLDAVMKARKDI--VARLQTQASA 153
G Q ++ ++TGA +++ +D G +++SG V KA+ I + T S
Sbjct: 69 GRQGANIKQLRKQTGARIDVD-TEDVGDERVLLISGFPVQVCKAKAAIHQILTENTPVSE 127
Query: 154 TVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDP----SNQIKITGTKEGIEKAR 209
+++P+ +IG+ GE ++ + + KI + + S IKI+GT++ + A+
Sbjct: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAK 187
Query: 210 HEVLLISAEQDK 221
H +L +E ++
Sbjct: 188 HLILEKVSEDEE 199
Score = 39.3 bits (90), Expect = 0.024
Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 6/99 (6%)
Query: 438 VEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSE---KSNLIRIEGDPQGVQQAK 494
+E+ + + + +IG+ GANI +++ Q RI D+E ++ I G P V +AK
Sbjct: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQ--TGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
Query: 495 RELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREI 533
+ ++ + ++ L + QR IIG+ GE IR I
Sbjct: 113 AAIHQILTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSI 150
Score = 32.3 bits (72), Expect = 3.0
Identities = 26/114 (22%), Positives = 56/114 (49%), Gaps = 11/114 (9%)
Query: 288 YEEKKKKTTT------IAVEVKKSQH--KYVIGPKGNSLQEILERTGVSVEIPPSDSISE 339
Y E +++ T I +E++ Q K +IG +G +++++ ++TG +++ D E
Sbjct: 37 YRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE 96
Query: 340 TVIL-RGEPEKLGQALTEVY--AKANSFTVSSVAAPSWLHRFIIGKKGQNLAKI 390
V+L G P ++ +A ++ N+ ++ P IIG+ G+ + I
Sbjct: 97 RVLLISGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSI 150
Score = 32.0 bits (71), Expect = 3.9
Identities = 43/214 (20%), Positives = 86/214 (40%), Gaps = 7/214 (3%)
Query: 157 IPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQI-KITGTKEGIEKARHEVLLI 215
+P+E + +IG+ G ++ L +T +I + D ++ I+G + KA+ + I
Sbjct: 59 VPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQI 118
Query: 216 SAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPS-----VNRTEIVF 270
E + E+L V + I G + I + +G +I S ++R +
Sbjct: 119 LTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKIS 177
Query: 271 TGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVE 330
+KE A ++K+ E+++ + + K I + + E ++
Sbjct: 178 GTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALW 237
Query: 331 IPPSDSISETVILRGEPEKLGQALTEVYAKANSF 364
S S+ T L P K G + V +K S+
Sbjct: 238 KNTSSSMEPTAPLVTPPPKGGGDMAVVVSKEGSW 271
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 55.5 bits (132), Expect = 3e-07
Identities = 43/151 (28%), Positives = 75/151 (49%), Gaps = 7/151 (4%)
Query: 579 ENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSE-TIIITGKRANCE 637
E+ I + + ++ K IIG+ GANIK++R+++ +ID+ E+ E ++I+G
Sbjct: 50 EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVC 109
Query: 638 AARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSG- 696
A++ I I + ++E ++S+P + +IG G IRSI + G I E G
Sbjct: 110 KAKAAIHQILTENTPVSE-QLSVPQRSVGRIIGRGGETIRSIC-KASGAKITCDKESEGT 167
Query: 697 ---SDTVVIRGPSSDVEKAKKQLLHLAEEKQ 724
S + I G +V AK +L E +
Sbjct: 168 LLLSRLIKISGTQKEVAAAKHLILEKVSEDE 198
Score = 45.8 bits (107), Expect = 3e-04
Identities = 38/157 (24%), Positives = 73/157 (46%), Gaps = 11/157 (7%)
Query: 973 VTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSD-IIAITGLAANLDRAK 1031
+ IE+ VP + + +IG++G+ I+++ + I V ++ + ++ I+G + +AK
Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
Query: 1032 AGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDK 1091
A + + + E E ++V + +IIGR G I I I +
Sbjct: 113 AAIHQILTENTPVSE---------QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKE 163
Query: 1092 DDGNQPQDQ-ITITGYEKNTEAARDAILRIVGELEQM 1127
+G + I I+G +K AA+ IL V E E++
Sbjct: 164 SEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEEL 200
Score = 45.4 bits (106), Expect = 3e-04
Identities = 43/182 (23%), Positives = 85/182 (46%), Gaps = 13/182 (7%)
Query: 710 EKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAEDK 769
E +++L + E+ +++R E K +IG+ G I+++R TGAR+ +
Sbjct: 39 ESREERLTFVGED----DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG 94
Query: 770 DQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEE 829
D+ ++ I G V +A+ + ++ + V + + V + + R G+ +R I +
Sbjct: 95 DERVLLISGFPVQVCKAKAAIHQILTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSICKA 153
Query: 830 YGGVMVSFPRS-GT--QSDKVTLKGAKDCVEAAKKRIQEII---EDLEAQV--TLECAIP 881
G + S GT S + + G + V AAK I E + E+L ++ + E +P
Sbjct: 154 SGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVP 213
Query: 882 QK 883
+K
Sbjct: 214 RK 215
Score = 42.4 bits (98), Expect = 0.003
Identities = 54/201 (26%), Positives = 81/201 (40%), Gaps = 14/201 (6%)
Query: 1067 IIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQ 1126
IIGR+GA I Q+R + I +D G++ + I+G+ A+ AI +I+ E
Sbjct: 67 IIGRQGANIKQLRKQTGARIDVDTEDVGDERV--LLISGFPVQVCKAKAAIHQILTE-NT 123
Query: 1127 MVSEDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPD---PNCVTVTGLPENV 1183
VSE + + R RIIG G+ IR I I + + ++G + V
Sbjct: 124 PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEV 183
Query: 1184 EEAIDHIL---NLEEEYLADVVDSEALQVYMKPP---AHEEAKAPSRGFVVRDAPWTASS 1237
A IL + +EE + S +V K P E+ P G A W +S
Sbjct: 184 AAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEP--GGAGEPALWKNTS 241
Query: 1238 SEKAPDMSSSEEFPSFGAQVA 1258
S P P G +A
Sbjct: 242 SSMEPTAPLVTPPPKGGGDMA 262
Score = 39.7 bits (91), Expect = 0.018
Identities = 32/132 (24%), Positives = 66/132 (50%), Gaps = 9/132 (6%)
Query: 98 GEQAKICLEIMQRTGAHLELSLAKDQGLS--IMVSGKLDAVMKARKDI--VARLQTQASA 153
G Q ++ ++TGA +++ +D G +++SG V KA+ I + T S
Sbjct: 69 GRQGANIKQLRKQTGARIDVD-TEDVGDERVLLISGFPVQVCKAKAAIHQILTENTPVSE 127
Query: 154 TVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDP----SNQIKITGTKEGIEKAR 209
+++P+ +IG+ GE ++ + + KI + + S IKI+GT++ + A+
Sbjct: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAK 187
Query: 210 HEVLLISAEQDK 221
H +L +E ++
Sbjct: 188 HLILEKVSEDEE 199
Score = 39.3 bits (90), Expect = 0.024
Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 6/99 (6%)
Query: 438 VEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSE---KSNLIRIEGDPQGVQQAK 494
+E+ + + + +IG+ GANI +++ Q RI D+E ++ I G P V +AK
Sbjct: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQ--TGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
Query: 495 RELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREI 533
+ ++ + ++ L + QR IIG+ GE IR I
Sbjct: 113 AAIHQILTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSI 150
Score = 32.3 bits (72), Expect = 3.0
Identities = 26/114 (22%), Positives = 56/114 (49%), Gaps = 11/114 (9%)
Query: 288 YEEKKKKTTT------IAVEVKKSQH--KYVIGPKGNSLQEILERTGVSVEIPPSDSISE 339
Y E +++ T I +E++ Q K +IG +G +++++ ++TG +++ D E
Sbjct: 37 YRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE 96
Query: 340 TVIL-RGEPEKLGQALTEVY--AKANSFTVSSVAAPSWLHRFIIGKKGQNLAKI 390
V+L G P ++ +A ++ N+ ++ P IIG+ G+ + I
Sbjct: 97 RVLLISGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSI 150
Score = 32.0 bits (71), Expect = 3.9
Identities = 43/214 (20%), Positives = 86/214 (40%), Gaps = 7/214 (3%)
Query: 157 IPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQI-KITGTKEGIEKARHEVLLI 215
+P+E + +IG+ G ++ L +T +I + D ++ I+G + KA+ + I
Sbjct: 59 VPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQI 118
Query: 216 SAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPS-----VNRTEIVF 270
E + E+L V + I G + I + +G +I S ++R +
Sbjct: 119 LTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKIS 177
Query: 271 TGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVE 330
+KE A ++K+ E+++ + + K I + + E ++
Sbjct: 178 GTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALW 237
Query: 331 IPPSDSISETVILRGEPEKLGQALTEVYAKANSF 364
S S+ T L P K G + V +K S+
Sbjct: 238 KNTSSSMEPTAPLVTPPPKGGGDMAVVVSKEGSW 271
>gi|145312256 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 55.5 bits (132), Expect = 3e-07
Identities = 43/151 (28%), Positives = 75/151 (49%), Gaps = 7/151 (4%)
Query: 579 ENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSE-TIIITGKRANCE 637
E+ I + + ++ K IIG+ GANIK++R+++ +ID+ E+ E ++I+G
Sbjct: 50 EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVC 109
Query: 638 AARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSG- 696
A++ I I + ++E ++S+P + +IG G IRSI + G I E G
Sbjct: 110 KAKAAIHQILTENTPVSE-QLSVPQRSVGRIIGRGGETIRSIC-KASGAKITCDKESEGT 167
Query: 697 ---SDTVVIRGPSSDVEKAKKQLLHLAEEKQ 724
S + I G +V AK +L E +
Sbjct: 168 LLLSRLIKISGTQKEVAAAKHLILEKVSEDE 198
Score = 45.8 bits (107), Expect = 3e-04
Identities = 38/157 (24%), Positives = 73/157 (46%), Gaps = 11/157 (7%)
Query: 973 VTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSD-IIAITGLAANLDRAK 1031
+ IE+ VP + + +IG++G+ I+++ + I V ++ + ++ I+G + +AK
Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
Query: 1032 AGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDK 1091
A + + + E E ++V + +IIGR G I I I +
Sbjct: 113 AAIHQILTENTPVSE---------QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKE 163
Query: 1092 DDGNQPQDQ-ITITGYEKNTEAARDAILRIVGELEQM 1127
+G + I I+G +K AA+ IL V E E++
Sbjct: 164 SEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEEL 200
Score = 45.4 bits (106), Expect = 3e-04
Identities = 43/182 (23%), Positives = 85/182 (46%), Gaps = 13/182 (7%)
Query: 710 EKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAEDK 769
E +++L + E+ +++R E K +IG+ G I+++R TGAR+ +
Sbjct: 39 ESREERLTFVGED----DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG 94
Query: 770 DQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEE 829
D+ ++ I G V +A+ + ++ + V + + V + + R G+ +R I +
Sbjct: 95 DERVLLISGFPVQVCKAKAAIHQILTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSICKA 153
Query: 830 YGGVMVSFPRS-GT--QSDKVTLKGAKDCVEAAKKRIQEII---EDLEAQV--TLECAIP 881
G + S GT S + + G + V AAK I E + E+L ++ + E +P
Sbjct: 154 SGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVP 213
Query: 882 QK 883
+K
Sbjct: 214 RK 215
Score = 42.4 bits (98), Expect = 0.003
Identities = 54/201 (26%), Positives = 81/201 (40%), Gaps = 14/201 (6%)
Query: 1067 IIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQ 1126
IIGR+GA I Q+R + I +D G++ + I+G+ A+ AI +I+ E
Sbjct: 67 IIGRQGANIKQLRKQTGARIDVDTEDVGDERV--LLISGFPVQVCKAKAAIHQILTE-NT 123
Query: 1127 MVSEDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPD---PNCVTVTGLPENV 1183
VSE + + R RIIG G+ IR I I + + ++G + V
Sbjct: 124 PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEV 183
Query: 1184 EEAIDHIL---NLEEEYLADVVDSEALQVYMKPP---AHEEAKAPSRGFVVRDAPWTASS 1237
A IL + +EE + S +V K P E+ P G A W +S
Sbjct: 184 AAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEP--GGAGEPALWKNTS 241
Query: 1238 SEKAPDMSSSEEFPSFGAQVA 1258
S P P G +A
Sbjct: 242 SSMEPTAPLVTPPPKGGGDMA 262
Score = 39.7 bits (91), Expect = 0.018
Identities = 32/132 (24%), Positives = 66/132 (50%), Gaps = 9/132 (6%)
Query: 98 GEQAKICLEIMQRTGAHLELSLAKDQGLS--IMVSGKLDAVMKARKDI--VARLQTQASA 153
G Q ++ ++TGA +++ +D G +++SG V KA+ I + T S
Sbjct: 69 GRQGANIKQLRKQTGARIDVD-TEDVGDERVLLISGFPVQVCKAKAAIHQILTENTPVSE 127
Query: 154 TVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDP----SNQIKITGTKEGIEKAR 209
+++P+ +IG+ GE ++ + + KI + + S IKI+GT++ + A+
Sbjct: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAK 187
Query: 210 HEVLLISAEQDK 221
H +L +E ++
Sbjct: 188 HLILEKVSEDEE 199
Score = 39.3 bits (90), Expect = 0.024
Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 6/99 (6%)
Query: 438 VEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSE---KSNLIRIEGDPQGVQQAK 494
+E+ + + + +IG+ GANI +++ Q RI D+E ++ I G P V +AK
Sbjct: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQ--TGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
Query: 495 RELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREI 533
+ ++ + ++ L + QR IIG+ GE IR I
Sbjct: 113 AAIHQILTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSI 150
Score = 32.3 bits (72), Expect = 3.0
Identities = 26/114 (22%), Positives = 56/114 (49%), Gaps = 11/114 (9%)
Query: 288 YEEKKKKTTT------IAVEVKKSQH--KYVIGPKGNSLQEILERTGVSVEIPPSDSISE 339
Y E +++ T I +E++ Q K +IG +G +++++ ++TG +++ D E
Sbjct: 37 YRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE 96
Query: 340 TVIL-RGEPEKLGQALTEVY--AKANSFTVSSVAAPSWLHRFIIGKKGQNLAKI 390
V+L G P ++ +A ++ N+ ++ P IIG+ G+ + I
Sbjct: 97 RVLLISGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSI 150
Score = 32.0 bits (71), Expect = 3.9
Identities = 43/214 (20%), Positives = 86/214 (40%), Gaps = 7/214 (3%)
Query: 157 IPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQI-KITGTKEGIEKARHEVLLI 215
+P+E + +IG+ G ++ L +T +I + D ++ I+G + KA+ + I
Sbjct: 59 VPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQI 118
Query: 216 SAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPS-----VNRTEIVF 270
E + E+L V + I G + I + +G +I S ++R +
Sbjct: 119 LTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKIS 177
Query: 271 TGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVE 330
+KE A ++K+ E+++ + + K I + + E ++
Sbjct: 178 GTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALW 237
Query: 331 IPPSDSISETVILRGEPEKLGQALTEVYAKANSF 364
S S+ T L P K G + V +K S+
Sbjct: 238 KNTSSSMEPTAPLVTPPPKGGGDMAVVVSKEGSW 271
>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
Length = 335
Score = 51.6 bits (122), Expect = 5e-06
Identities = 69/298 (23%), Positives = 125/298 (41%), Gaps = 37/298 (12%)
Query: 521 TIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKC----TKYMQKMVAD 576
+IIG+KGE ++++R++ IN + I+ L GP N + K +++ ++
Sbjct: 27 SIIGKKGESVKKMREE-SGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISS 85
Query: 577 LVENSYSISVP-------IFKQFHKNIIGKGGANIKKIREESNTKIDLPAE---NSNSET 626
+ NS + S P + ++IGKGG IK+IRE + ++ + + NS
Sbjct: 86 SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERA 145
Query: 627 IIITG-KRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNS-----LIGTKGRLIR--- 677
I I G ++ E + + + + L+ V+IP + S G + I+
Sbjct: 146 ITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQY 205
Query: 678 -------SIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTV 730
+ + + HFP+ + I S +V K L QT S +
Sbjct: 206 AIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEV---KGYWAGLDASAQTTSHEL 262
Query: 731 DIRAKPEYHKFLIGKGGGKIRKVRDSTGARV-IFPAAEDKDQDLITIIGKEDAVREAQ 787
I + +IG+ G KI ++R +GA++ I E +TI G ++ AQ
Sbjct: 263 TI--PNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 318
Score = 50.1 bits (118), Expect = 1e-05
Identities = 72/292 (24%), Positives = 113/292 (38%), Gaps = 33/292 (11%)
Query: 667 SLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTK 726
S+IG KG ++ + EE G I+ + + GP++ + KA ++ EE +
Sbjct: 27 SIIGKKGESVKKMREE-SGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISS 85
Query: 727 SFTVDIRAK-----------PEYHKFLIGKGGGKIRKVRDSTGARVIFPA--AEDKDQDL 773
S T A LIGKGG KI+++R+STGA+V + +
Sbjct: 86 SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERA 145
Query: 774 ITIIGKEDAVREAQKE-----LEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAE 828
ITI G ++ E K+ LE L Q+ V ++ PK VI G I
Sbjct: 146 ITIAGIPQSIIECVKQICVVMLETLSQSPPKGV--TIPYRPKPSSSPVIFAGGQAYTIQG 203
Query: 829 EYG---GVMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEIIE-----DLEAQVTL-ECA 879
+Y + + Q + + E+ D AQ T E
Sbjct: 204 QYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELT 263
Query: 880 IPQKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQENGDEA 931
IP ++G +G++I +I + QIK + E ST+ V G A
Sbjct: 264 IPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEG---STDRQVTITGSAA 312
Score = 45.8 bits (107), Expect = 3e-04
Identities = 70/304 (23%), Positives = 120/304 (39%), Gaps = 55/304 (18%)
Query: 379 IIGKKGQNLAKITQQMPKVHIEFTEG---EDKITLEGPTEDVNVAQEQI-EGMVKDLINR 434
IIGKKG+++ K+ ++ I +EG E ITL GPT + A I + + +D+ +
Sbjct: 28 IIGKKGESVKKMREESG-ARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSS 86
Query: 435 MDY----------VEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPD---SEKSNLI 481
M + + + LIGK G I I++ V++ D + I
Sbjct: 87 MTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAI 146
Query: 482 RIEGDPQGVQQAKREL-LELASRMENERTKDLIIEQR-------------FHRTIIGQ-- 525
I G PQ + + +++ + + + K + I R TI GQ
Sbjct: 147 TIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYA 206
Query: 526 -------KGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLV 578
K ++ + FP N +S +++G Y + A
Sbjct: 207 IPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKG----------YWAGLDASAQ 256
Query: 579 ENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDL--PAENSNSETIIITGKRANC 636
S+ +++P IIG+ GA I +IR+ S +I + P E S + ITG A+
Sbjct: 257 TTSHELTIP--NDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASI 314
Query: 637 EAAR 640
A+
Sbjct: 315 SLAQ 318
Score = 45.4 bits (106), Expect = 3e-04
Identities = 49/196 (25%), Positives = 83/196 (42%), Gaps = 22/196 (11%)
Query: 573 MVADLVENSYSISVPIFKQFHK----NIIGKGGANIKKIREESNTKIDLPAENSNSETII 628
M ++E ++++ I H +IIGK G ++KK+REES +I++ N I
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 629 ITG-KRANCEAARSRILSIQKDLANI-----------AEVEVSIPAKLHNSLIGTKGRLI 676
+ G A +A I +++D+++ + + +PA SLIG G I
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 677 RSIMEECGG-VHIHFP-VEGSGSDTVVIRG-PSSDVEKAKK---QLLHLAEEKQTKSFTV 730
+ I E G V + + S + I G P S +E K+ +L + K T+
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
Query: 731 DIRAKPEYHKFLIGKG 746
R KP + G
Sbjct: 181 PYRPKPSSSPVIFAGG 196
Score = 42.0 bits (97), Expect = 0.004
Identities = 61/296 (20%), Positives = 110/296 (37%), Gaps = 43/296 (14%)
Query: 237 IAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEK----- 291
I G V ++ +E+G RINI + I G + +A A I EE
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSM 87
Query: 292 ------KKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPS---DSISETVI 342
+ T+ + V SQ +IG G ++EI E TG V++ +S +
Sbjct: 88 TNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAIT 147
Query: 343 LRGEPEKLGQALTEV---------YAKANSFTVSSVAAPSWLHRFIIGK-----KGQ--- 385
+ G P+ + + + ++ + T+ PS G +GQ
Sbjct: 148 IAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAI 207
Query: 386 ---NLAKITQ-QMPKVHIEFTEGEDKIT-LEGPTEDVNVAQEQIEGMVKDLINRMDYVEI 440
+L K+ Q M + H T G + +E + +V ++ + + E+
Sbjct: 208 PQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSH-----EL 262
Query: 441 NIDHKFHRHLIGKSGANINRIKDQYKVSVRI--PPDSEKSNLIRIEGDPQGVQQAK 494
I + +IG+ GA IN I+ ++I P + + I G + A+
Sbjct: 263 TIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 318
Score = 40.4 bits (93), Expect = 0.011
Identities = 34/156 (21%), Positives = 68/156 (43%), Gaps = 5/156 (3%)
Query: 987 VIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQE 1046
+IG+KG ++KM +E I++ II + G + +A A ++++++E +
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSM 87
Query: 1047 DRALRSFKLSVT----VDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQIT 1102
+ + + VT V +IG+ G I +IR +Q N + IT
Sbjct: 88 TNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAIT 147
Query: 1103 ITGYEKN-TEAARDAILRIVGELEQMVSEDVPLDHR 1137
I G ++ E + + ++ L Q + V + +R
Sbjct: 148 IAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYR 183
Score = 35.8 bits (81), Expect = 0.27
Identities = 26/139 (18%), Positives = 61/139 (43%), Gaps = 18/139 (12%)
Query: 98 GEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVA- 156
G++ + ++ + +GA + +S I ++G +A+ KA I+ +L+ S+++
Sbjct: 30 GKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTN 89
Query: 157 --------------IPKEHHRFVIGKNGEKLQDLELKTATKIQIP---RPDDPSNQIKIT 199
+P +IGK G K++++ T ++Q+ P+ I I
Sbjct: 90 STAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIA 149
Query: 200 GTKEGIEKARHEVLLISAE 218
G + I + ++ ++ E
Sbjct: 150 GIPQSIIECVKQICVVMLE 168
Score = 30.8 bits (68), Expect = 8.6
Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 152 SATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPS--NQIKITGTKEGIEKAR 209
S + IP + +IG+ G K+ ++ + +I+I P + S Q+ ITG+ I A+
Sbjct: 259 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 318
Query: 210 H 210
+
Sbjct: 319 Y 319
>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
Length = 345
Score = 51.6 bits (122), Expect = 5e-06
Identities = 59/268 (22%), Positives = 108/268 (40%), Gaps = 34/268 (12%)
Query: 667 SLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTK 726
S+IG KG ++ + EE G I+ V I GP+ + KA + + EE
Sbjct: 59 SIIGKKGETVKKMREE-SGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIIN 117
Query: 727 SF-----------TVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPA--AEDKDQDL 773
S T+ + LIGKGG KI+++R+STGA+V + +
Sbjct: 118 SMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERA 177
Query: 774 ITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGGV 833
+TI G DA+ + K++ ++ + + P + L ++A +
Sbjct: 178 VTISGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTK---------LHQLAMQ---- 224
Query: 834 MVSFPRSGTQS-----DKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFHRSV 888
FP G + +K+ L +++ + ++ T E IP +
Sbjct: 225 QTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQ--SSGLDASPPASTHELTIPNDLIGCI 282
Query: 889 MGPKGSRIQQITRDFSVQIKFPDREENA 916
+G +G++I +I + QIK + E +
Sbjct: 283 IGRQGTKINEIRQMSGAQIKIANATEGS 310
Score = 48.9 bits (115), Expect = 3e-05
Identities = 67/295 (22%), Positives = 121/295 (41%), Gaps = 43/295 (14%)
Query: 521 TIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVEN 580
+IIG+KGE ++++R++ IN + IV + GP + + K + + + N
Sbjct: 59 SIIGKKGETVKKMREE-SGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIIN 117
Query: 581 SYSISVPIFK-----------QFHKNIIGKGGANIKKIREESNTKIDLPAE---NSNSET 626
S S S K ++IGKGG+ IK+IRE + ++ + + NS
Sbjct: 118 SMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERA 177
Query: 627 IIITGKRANCEAARSRILSIQKDLANIAEVEVSIP----AKLHNSLIGTKGRLIRSIMEE 682
+ I+G +I + + I + + +IP KLH + ++
Sbjct: 178 VTISGTPDAIIQCVKQICVVMLEAYTI-QGQYAIPHPDLTKLHQL------AMQQTPFPP 230
Query: 683 CGGVHIHFPVE----GSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEY 738
G + FP E S + + G SS ++ + H ++ +
Sbjct: 231 LGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTH------------ELTIPNDL 278
Query: 739 HKFLIGKGGGKIRKVRDSTGARV-IFPAAEDKDQDLITIIGKEDAVREAQKELEA 792
+IG+ G KI ++R +GA++ I A E + ITI G + AQ + A
Sbjct: 279 IGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINA 333
Score = 48.5 bits (114), Expect = 4e-05
Identities = 55/294 (18%), Positives = 118/294 (40%), Gaps = 46/294 (15%)
Query: 98 GEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKA--------RKDIVARLQT 149
G++ + ++ + +GA + +S + ++G DA+ KA +DI+ +
Sbjct: 62 GKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSN 121
Query: 150 QASAT-------VAIPKEHHRFVIGKNGEKLQDLELKTATKIQIP---RPDDPSNQIKIT 199
+ + + +P +IGK G K++++ T ++Q+ P+ + I+
Sbjct: 122 SPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTIS 181
Query: 200 GTKEGIEKARHEVLLISAE----QDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTR 255
GT + I + ++ ++ E Q + A+ HP + +L MQ+T
Sbjct: 182 GTPDAIIQCVKQICVVMLEAYTIQGQYAIP--------HPDL----TKLHQLAMQQT--- 226
Query: 256 INIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYE----EKKKKTTTIAVEVKKSQHKYVI 311
P P + +T F GEK L + + + + +T + + +I
Sbjct: 227 ---PFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCII 283
Query: 312 GPKGNSLQEILERTGVSVEI--PPSDSISETVILRGEPEKLGQALTEVYAKANS 363
G +G + EI + +G ++I S + + G P + A + A+ S
Sbjct: 284 GRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARLTS 337
Score = 41.2 bits (95), Expect = 0.006
Identities = 61/297 (20%), Positives = 117/297 (39%), Gaps = 40/297 (13%)
Query: 165 VIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKA------RHEVLLISAE 218
+IGK GE ++ + ++ +I I + P + ITG + I KA + E +I++
Sbjct: 60 IIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSM 119
Query: 219 QDKRAVE------RLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPP---PSVNRTEIV 269
+ A RL V + + G + EI + TG ++ + P+ +
Sbjct: 120 SNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVT 179
Query: 270 FTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSV 329
+G + + Q V K+ + +E Q +Y I L ++ +
Sbjct: 180 ISGTPDAIIQCV-----------KQICVVMLEAYTIQGQYAI--PHPDLTKLHQLAMQQT 226
Query: 330 EIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSVAA------PSWLHRFIIGKK 383
PP + P + + +++ S A+ P+ L IIG++
Sbjct: 227 PFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQ 286
Query: 384 GQNLAKITQQMPKVHIEF---TEG--EDKITLEGPTEDVNVAQEQIEGMVKDLINRM 435
G + +I +QM I+ TEG E +IT+ G ++++AQ I + + M
Sbjct: 287 GTKINEI-RQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARLTSEVTGM 342
Score = 40.0 bits (92), Expect = 0.014
Identities = 54/285 (18%), Positives = 112/285 (39%), Gaps = 37/285 (12%)
Query: 450 LIGKSGANINRIKDQYKVSVRIPPDSEKSNLIRIEGDPQGVQQAKRELL-----ELASRM 504
+IGK G + +++++ + I + ++ I G + +A + ++ + M
Sbjct: 60 IIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSM 119
Query: 505 ENER-------TKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPD--PAQKSDIVQ 555
N T L++ ++IG+ G +I+EIR+ + D P V
Sbjct: 120 SNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVT 179
Query: 556 LRGPKNEVEKCTKY--MQKMVADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNT 613
+ G + + +C K + + A ++ Y+I P + H+ + + T
Sbjct: 180 ISGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQ-----TPFPPLGQT 234
Query: 614 KIDLPAE----NSNSETIIITGKRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLI 669
P E +S+ E + G+ + +A+ + E++IP L +I
Sbjct: 235 NPAFPGEKLPLHSSEEAQNLMGQSSGLDAS-----------PPASTHELTIPNDLIGCII 283
Query: 670 GTKGRLIRSIMEECGG-VHIHFPVEGSGSDTVVIRGPSSDVEKAK 713
G +G I I + G + I EGS + I G +++ A+
Sbjct: 284 GRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQ 328
Score = 37.7 bits (86), Expect = 0.070
Identities = 34/142 (23%), Positives = 61/142 (42%), Gaps = 11/142 (7%)
Query: 987 VIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQE 1046
+IG+KG ++KM +E I++ I+ ITG + +A A + + +E
Sbjct: 60 IIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSM 119
Query: 1047 DRALRSFKLSVT----VDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQIT 1102
+ + K VT V +IG+ G+ I +IR +Q N + +T
Sbjct: 120 SNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVT 179
Query: 1103 ITGYEKNTEAARDAILRIVGEL 1124
I+G DAI++ V ++
Sbjct: 180 ISG-------TPDAIIQCVKQI 194
Score = 36.2 bits (82), Expect = 0.20
Identities = 75/338 (22%), Positives = 120/338 (35%), Gaps = 60/338 (17%)
Query: 805 MLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSDKVTLKGAKDCVEAAKKRI- 863
+L+ K + ++G+ ++++ EE G ++ VT+ G D + A I
Sbjct: 50 LLMHGKEVGSIIGKKGETVKKMREE-SGARINISEGNCPERIVTITGPTDAIFKAFAMIA 108
Query: 864 ----QEIIEDL-------EAQVTLECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKFPDR 912
++II + + VTL +P S++G GS+I++I
Sbjct: 109 YKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIR------------ 156
Query: 913 EENAVHSTEPVVQENGDEAGEGREAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVP 972
ST VQ GD E G+P II K+ C EA
Sbjct: 157 -----ESTGAQVQVAGDMLPNSTERAVTISGTPD----AIIQCVKQICVVMLEAYTIQGQ 207
Query: 973 VTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKA 1032
I LH+ + Q P P L A G L +
Sbjct: 208 YAIPHPDLTKLHQLAMQQ-----------------TPFPPLGQTNPAFPGEKLPLHSS-- 248
Query: 1033 GLLERVKELQAEQE--DRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPD 1090
E + L + D + + +T+ IIGR+G I +IR I+ +
Sbjct: 249 ---EEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIAN 305
Query: 1091 KDDGNQPQDQITITGYEKNTEAARDAI-LRIVGELEQM 1127
+G+ + QITITG N A+ I R+ E+ M
Sbjct: 306 ATEGSS-ERQITITGTPANISLAQYLINARLTSEVTGM 342
>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
Length = 371
Score = 50.8 bits (120), Expect = 8e-06
Identities = 39/137 (28%), Positives = 62/137 (45%), Gaps = 14/137 (10%)
Query: 667 SLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTK 726
S+IG KG ++ + EE G I+ V I GP+ + KA + + EE
Sbjct: 59 SIIGKKGETVKKMREE-SGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIIN 117
Query: 727 SF-----------TVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPA--AEDKDQDL 773
S T+ + LIGKGG KI+++R+STGA+V + +
Sbjct: 118 SMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERA 177
Query: 774 ITIIGKEDAVREAQKEL 790
+TI G DA+ + K++
Sbjct: 178 VTISGTPDAIIQCVKQI 194
Score = 50.4 bits (119), Expect = 1e-05
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 18/187 (9%)
Query: 568 KYMQKMVADLVENSYSISVPIFKQFHK----NIIGKGGANIKKIREESNTKIDLPAENSN 623
++ ++M + + E ++++ I H +IIGK G +KK+REES +I++ N
Sbjct: 28 QFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP 87
Query: 624 SETIIITGKR-ANCEAARSRILSIQKDLANI-----------AEVEVSIPAKLHNSLIGT 671
+ ITG A +A ++D+ N + + +PA SLIG
Sbjct: 88 ERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGK 147
Query: 672 KGRLIRSIMEECGG-VHIHFP-VEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFT 729
G I+ I E G V + + S V I G + + KQ+ + E K T
Sbjct: 148 GGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGAT 207
Query: 730 VDIRAKP 736
+ R KP
Sbjct: 208 IPYRPKP 214
Score = 47.0 bits (110), Expect = 1e-04
Identities = 66/311 (21%), Positives = 123/311 (39%), Gaps = 42/311 (13%)
Query: 165 VIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKA------RHEVLLISAE 218
+IGK GE ++ + ++ +I I + P + ITG + I KA + E +I++
Sbjct: 60 IIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSM 119
Query: 219 QDKRAVE------RLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPP---PSVNRTEIV 269
+ A RL V + + G + EI + TG ++ + P+ +
Sbjct: 120 SNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVT 179
Query: 270 FTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKS--------------QHKYVIGPKG 315
+G + + Q V +I + E K TI K + Q +Y I P
Sbjct: 180 ISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAI-PHP 238
Query: 316 NSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSVAA---- 371
+ L ++ + PP + P + + +++ S A+
Sbjct: 239 DQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHEL 298
Query: 372 --PSWLHRFIIGKKGQNLAKITQQMPKVHIEF---TEG--EDKITLEGPTEDVNVAQEQI 424
P+ L IIG++G + +I +QM I+ TEG E +IT+ G ++++AQ I
Sbjct: 299 TIPNDLIGCIIGRQGTKINEI-RQMSGAQIKIANATEGSSERQITITGTPANISLAQYLI 357
Query: 425 EGMVKDLINRM 435
+ + M
Sbjct: 358 NARLTSEVTGM 368
Score = 46.6 bits (109), Expect = 2e-04
Identities = 57/308 (18%), Positives = 119/308 (38%), Gaps = 48/308 (15%)
Query: 98 GEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKA--------RKDIVARLQT 149
G++ + ++ + +GA + +S + ++G DA+ KA +DI+ +
Sbjct: 62 GKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSN 121
Query: 150 QASAT-------VAIPKEHHRFVIGKNGEKLQDLELKTATKIQIP---RPDDPSNQIKIT 199
+ + + +P +IGK G K++++ T ++Q+ P+ + I+
Sbjct: 122 SPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTIS 181
Query: 200 GTKEGIEKARHEVLLISAEQ-DKRAVERLEVEKAFHP--FIAGPYNRLVGE--------- 247
GT + I + ++ ++ E K A + A P F G + G+
Sbjct: 182 GTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQL 241
Query: 248 ------IMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYE----EKKKKTTT 297
MQ+T P P + +T F GEK L + + + + +T
Sbjct: 242 TKLHQLAMQQT------PFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPAST 295
Query: 298 IAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEI--PPSDSISETVILRGEPEKLGQALT 355
+ + +IG +G + EI + +G ++I S + + G P + A
Sbjct: 296 HELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQY 355
Query: 356 EVYAKANS 363
+ A+ S
Sbjct: 356 LINARLTS 363
Score = 45.1 bits (105), Expect = 4e-04
Identities = 67/306 (21%), Positives = 125/306 (40%), Gaps = 39/306 (12%)
Query: 521 TIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYM----QKMVAD 576
+IIG+KGE ++++R++ IN + IV + GP + + K + ++ + +
Sbjct: 59 SIIGKKGETVKKMREE-SGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIIN 117
Query: 577 LVENSYSISVP-------IFKQFHKNIIGKGGANIKKIREESNTKIDLPAE---NSNSET 626
+ NS + S P + ++IGKGG+ IK+IRE + ++ + + NS
Sbjct: 118 SMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERA 177
Query: 627 IIITGKRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGV 686
+ I+G +I + + P +I G+ G
Sbjct: 178 VTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTI----QGQY 233
Query: 687 HIHFPVEGSGSDTVVIR-------GPSSDVEKAKKQLLHLAEEKQT---KSFTVDIRAKP 736
I P + + + ++ G ++ +K LH +EE Q +S +D
Sbjct: 234 AIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPA 293
Query: 737 EYHKF---------LIGKGGGKIRKVRDSTGARV-IFPAAEDKDQDLITIIGKEDAVREA 786
H+ +IG+ G KI ++R +GA++ I A E + ITI G + A
Sbjct: 294 STHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLA 353
Query: 787 QKELEA 792
Q + A
Sbjct: 354 QYLINA 359
Score = 43.9 bits (102), Expect = 0.001
Identities = 70/304 (23%), Positives = 117/304 (38%), Gaps = 51/304 (16%)
Query: 379 IIGKKGQNLAKITQQMPKVHIEFTEG---EDKITLEGPTEDVNVAQEQIE-GMVKDLINR 434
IIGKKG+ + K+ ++ I +EG E +T+ GPT+ + A I +D+IN
Sbjct: 60 IIGKKGETVKKMREESG-ARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINS 118
Query: 435 MDY----------VEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPD---SEKSNLI 481
M + + + LIGK G+ I I++ V++ D + +
Sbjct: 119 MSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAV 178
Query: 482 RIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFH--RTIIGQKGERIREIRDKFPE 539
I G P + Q +++ + M K I R T + G + I+ ++
Sbjct: 179 TISGTPDAIIQCVKQICVV---MLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYA- 234
Query: 540 VIINFPDPAQKSDIVQL------------RGPKNEVEKCTKYMQKMVADLVENSYSISVP 587
P P Q + + QL P EK + + +L+ S +
Sbjct: 235 ----IPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDAS 290
Query: 588 IFKQFHK---------NIIGKGGANIKKIREESNTKIDL--PAENSNSETIIITGKRANC 636
H+ IIG+ G I +IR+ S +I + E S+ I ITG AN
Sbjct: 291 PPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANI 350
Query: 637 EAAR 640
A+
Sbjct: 351 SLAQ 354
Score = 39.3 bits (90), Expect = 0.024
Identities = 36/151 (23%), Positives = 65/151 (43%), Gaps = 11/151 (7%)
Query: 987 VIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQE 1046
+IG+KG ++KM +E I++ I+ ITG + +A A + + +E
Sbjct: 60 IIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSM 119
Query: 1047 DRALRSFKLSVT----VDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQIT 1102
+ + K VT V +IG+ G+ I +IR +Q N + +T
Sbjct: 120 SNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVT 179
Query: 1103 ITGYEKNTEAARDAILRIVGELEQMVSEDVP 1133
I+G DAI++ V ++ ++ E P
Sbjct: 180 ISG-------TPDAIIQCVKQICVVMLESPP 203
Score = 32.3 bits (72), Expect = 3.0
Identities = 29/130 (22%), Positives = 56/130 (43%), Gaps = 18/130 (13%)
Query: 805 MLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSDKVTLKGAKDCVEAAKKRI- 863
+L+ K + ++G+ ++++ EE G ++ VT+ G D + A I
Sbjct: 50 LLMHGKEVGSIIGKKGETVKKMREE-SGARINISEGNCPERIVTITGPTDAIFKAFAMIA 108
Query: 864 ----QEIIEDL-------EAQVTLECAIPQKFHRSVMGPKGSRIQQITRDFSVQIK---- 908
++II + + VTL +P S++G GS+I++I Q++
Sbjct: 109 YKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGD 168
Query: 909 -FPDREENAV 917
P+ E AV
Sbjct: 169 MLPNSTERAV 178
Score = 31.2 bits (69), Expect = 6.6
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
Query: 1067 IIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAI-LRIVGELE 1125
IIGR+G I +IR I+ + +G+ + QITITG N A+ I R+ E+
Sbjct: 308 IIGRQGTKINEIRQMSGAQIKIANATEGSS-ERQITITGTPANISLAQYLINARLTSEVT 366
Query: 1126 QM 1127
M
Sbjct: 367 GM 368
>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
Length = 362
Score = 50.4 bits (119), Expect = 1e-05
Identities = 85/384 (22%), Positives = 141/384 (36%), Gaps = 70/384 (18%)
Query: 573 MVADLVENSYSISVPIFKQFHK----NIIGKGGANIKKIREESNTKIDLPAENSNSETII 628
M ++E ++++ I H +IIGK G ++KK+REES +I++ N I
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 629 ITG-KRANCEAARSRILSIQKDLANI-----------AEVEVSIPAKLHNSLIGTKGRLI 676
+ G A +A I +++D+++ + + +PA SLIG G I
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 677 RSIMEECGG-VHIHFP-VEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRA 734
+ I E G V + + S + I G + + KQ+ + E K T+ R
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 735 KPEYHKFLIGKGGGKIRKVRDS------TGARVIFPAAEDKDQDLITIIGKEDAVREAQK 788
KP + G + DS T + + P E + TI G+ +
Sbjct: 181 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 240
Query: 789 ELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSDKVT 848
+L L HF + G SG +S
Sbjct: 241 KLHQLAM---------------QQSHFPMTHGNT---------------GFSGIESSSPE 270
Query: 849 LKGAKDCVEAAKKRIQEIIEDLEAQVTL-ECAIPQKFHRSVMGPKGSRIQQITRDFSVQI 907
+KG ++A+ AQ T E IP ++G +G++I +I + QI
Sbjct: 271 VKGYWAGLDAS------------AQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQI 318
Query: 908 KFPDREENAVHSTEPVVQENGDEA 931
K + E ST+ V G A
Sbjct: 319 KIANPVEG---STDRQVTITGSAA 339
Score = 44.3 bits (103), Expect = 8e-04
Identities = 34/125 (27%), Positives = 61/125 (48%), Gaps = 15/125 (12%)
Query: 521 TIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKC----TKYMQKMVAD 576
+IIG+KGE ++++R++ IN + I+ L GP N + K +++ ++
Sbjct: 27 SIIGKKGESVKKMREE-SGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISS 85
Query: 577 LVENSYSISVP-------IFKQFHKNIIGKGGANIKKIREESNTKIDLPAE---NSNSET 626
+ NS + S P + ++IGKGG IK+IRE + ++ + + NS
Sbjct: 86 SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERA 145
Query: 627 IIITG 631
I I G
Sbjct: 146 ITIAG 150
Score = 40.4 bits (93), Expect = 0.011
Identities = 84/359 (23%), Positives = 136/359 (37%), Gaps = 65/359 (18%)
Query: 379 IIGKKGQNLAKITQQMPKVHIEFTEG---EDKITLEGPTEDVNVAQEQI-EGMVKDLINR 434
IIGKKG+++ K+ ++ I +EG E ITL GPT + A I + + +D+ +
Sbjct: 28 IIGKKGESVKKMREESG-ARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSS 86
Query: 435 MDY----------VEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPD---SEKSNLI 481
M + + + LIGK G I I++ V++ D + I
Sbjct: 87 MTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAI 146
Query: 482 RIEGDPQGVQQAKRELLELASRMENERTKDLIIEQR---FHRTII---GQKGERIREIRD 535
I G PQ + + +++ + M K + I R +I GQ
Sbjct: 147 TIAGIPQSIIECVKQICVV---MLESPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSA 203
Query: 536 KFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKN 595
FP P D L GP E A ++ Y+I P + H+
Sbjct: 204 SFPHTT---PSMCLNPD---LEGPPLE------------AYTIQGQYAIPQPDLTKLHQL 245
Query: 596 IIGKGGANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIAE 655
+ + + NT E+S+ E + G A +A+ A
Sbjct: 246 AMQQSHFPM----THGNTGFS-GIESSSPE---VKGYWAGLDAS-----------AQTTS 286
Query: 656 VEVSIPAKLHNSLIGTKGRLIRSIMEECGG-VHIHFPVEGSGSDTVVIRGPSSDVEKAK 713
E++IP L +IG +G I I + G + I PVEGS V I G ++ + A+
Sbjct: 287 HELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 345
Score = 38.5 bits (88), Expect = 0.041
Identities = 32/135 (23%), Positives = 56/135 (41%), Gaps = 14/135 (10%)
Query: 237 IAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEK----- 291
I G V ++ +E+G RINI + I G + +A A I EE
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSM 87
Query: 292 ------KKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPS---DSISETVI 342
+ T+ + V SQ +IG G ++EI E TG V++ +S +
Sbjct: 88 TNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAIT 147
Query: 343 LRGEPEKLGQALTEV 357
+ G P+ + + + ++
Sbjct: 148 IAGIPQSIIECVKQI 162
Score = 38.5 bits (88), Expect = 0.041
Identities = 29/123 (23%), Positives = 54/123 (43%), Gaps = 4/123 (3%)
Query: 987 VIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQE 1046
+IG+KG ++KM +E I++ II + G + +A A ++++++E +
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSM 87
Query: 1047 DRALRSFKLSVT----VDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQIT 1102
+ + + VT V +IG+ G I +IR +Q N + IT
Sbjct: 88 TNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAIT 147
Query: 1103 ITG 1105
I G
Sbjct: 148 IAG 150
Score = 37.4 bits (85), Expect = 0.092
Identities = 27/145 (18%), Positives = 63/145 (43%), Gaps = 18/145 (12%)
Query: 98 GEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVA- 156
G++ + ++ + +GA + +S I ++G +A+ KA I+ +L+ S+++
Sbjct: 30 GKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTN 89
Query: 157 --------------IPKEHHRFVIGKNGEKLQDLELKTATKIQIP---RPDDPSNQIKIT 199
+P +IGK G K++++ T ++Q+ P+ I I
Sbjct: 90 STAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIA 149
Query: 200 GTKEGIEKARHEVLLISAEQDKRAV 224
G + I + ++ ++ E + V
Sbjct: 150 GIPQSIIECVKQICVVMLESPPKGV 174
Score = 34.7 bits (78), Expect = 0.59
Identities = 66/351 (18%), Positives = 120/351 (34%), Gaps = 54/351 (15%)
Query: 165 VIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQD---- 220
+IGK GE ++ + ++ +I I + P I + G I KA +++ E+D
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKA-FAMIIDKLEEDISSS 86
Query: 221 ---------KRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPP---PSVNRTEI 268
RL V + + G + EI + TG ++ + P+ I
Sbjct: 87 MTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAI 146
Query: 269 VFTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVS 328
G + + + V +I + E K TI K S + Q+ S
Sbjct: 147 TIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFA----GGQDRYSTGSDS 202
Query: 329 VEIP-PSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSVAAPSWLHRFIIGKKGQNL 387
P + S+ L G P E Y + + +L
Sbjct: 203 ASFPHTTPSMCLNPDLEGPP-------LEAYTIQGQYAIPQ----------------PDL 239
Query: 388 AKITQ-QMPKVHIEFTEGEDKIT-LEGPTEDVNVAQEQIEGMVKDLINRMDYVEINIDHK 445
K+ Q M + H T G + +E + +V ++ + + E+ I +
Sbjct: 240 TKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSH-----ELTIPND 294
Query: 446 FHRHLIGKSGANINRIKDQYKVSVRI--PPDSEKSNLIRIEGDPQGVQQAK 494
+IG+ GA IN I+ ++I P + + I G + A+
Sbjct: 295 LIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 345
Score = 30.8 bits (68), Expect = 8.6
Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 152 SATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPS--NQIKITGTKEGIEKAR 209
S + IP + +IG+ G K+ ++ + +I+I P + S Q+ ITG+ I A+
Sbjct: 286 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 345
Query: 210 H 210
+
Sbjct: 346 Y 346
>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
Length = 356
Score = 50.1 bits (118), Expect = 1e-05
Identities = 41/137 (29%), Positives = 63/137 (45%), Gaps = 14/137 (10%)
Query: 667 SLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTK 726
S+IG KG ++ I EE G I+ + + GP++ + KA ++ EE
Sbjct: 27 SIIGKKGESVKRIREE-SGARINISEGNCPERIITLTGPTNAIFKAFAMIIDKLEEDINS 85
Query: 727 SFTVDIRAK--PEYHKF---------LIGKGGGKIRKVRDSTGARVIFPA--AEDKDQDL 773
S T A P + LIGKGG KI+++R+STGA+V + +
Sbjct: 86 SMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERA 145
Query: 774 ITIIGKEDAVREAQKEL 790
ITI G +V E K++
Sbjct: 146 ITIAGVPQSVTECVKQI 162
Score = 48.9 bits (115), Expect = 3e-05
Identities = 75/326 (23%), Positives = 129/326 (39%), Gaps = 53/326 (16%)
Query: 521 TIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKC-TKYMQKMVADL-- 577
+IIG+KGE ++ IR++ IN + I+ L GP N + K + K+ D+
Sbjct: 27 SIIGKKGESVKRIREE-SGARINISEGNCPERIITLTGPTNAIFKAFAMIIDKLEEDINS 85
Query: 578 -VENSYSISVP-------IFKQFHKNIIGKGGANIKKIREESNTKIDLPAE---NSNSET 626
+ NS + S P + ++IGKGG IK+IRE + ++ + + NS
Sbjct: 86 SMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERA 145
Query: 627 IIITG-KRANCEAARSRILSIQKDLANIAEVEVSI----PAKLHNSLIGTKGRLIRSIME 681
I I G ++ E + L + + L+ + V P + +I G+ +
Sbjct: 146 ITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQPMPASSPVICAGGQ--DRCSD 203
Query: 682 ECGGVHIHFPVEGSGSDTVVIRGPS--SDVEKAK-----KQLLHLAEEKQTKSFTVDIRA 734
G H +EG D I+G S ++ AK +Q H A F +
Sbjct: 204 AAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQVARQQSHFAMMHGGTGFAGIDSS 263
Query: 735 KPEYHKF-----------------------LIGKGGGKIRKVRDSTGARV-IFPAAEDKD 770
PE + +IG+ G I ++R +GA++ I E
Sbjct: 264 SPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSS 323
Query: 771 QDLITIIGKEDAVREAQKELEALIQN 796
+TI G ++ AQ + A + +
Sbjct: 324 GRQVTITGSAASISLAQYLINARLSS 349
Score = 43.1 bits (100), Expect = 0.002
Identities = 48/187 (25%), Positives = 81/187 (43%), Gaps = 23/187 (12%)
Query: 573 MVADLVENSYSISVPIFKQFHK----NIIGKGGANIKKIREESNTKIDLPAENSNSETII 628
M A + E+ ++++ I H +IIGK G ++K+IREES +I++ N I
Sbjct: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60
Query: 629 ITG-KRANCEAARSRILSIQKDLANI-----------AEVEVSIPAKLHNSLIGTKGRLI 676
+TG A +A I +++D+ + + + +PA SLIG G I
Sbjct: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120
Query: 677 RSIMEECGG-VHIHFP-VEGSGSDTVVIRGPSSDVEKAKKQ-----LLHLAEEKQTKSFT 729
+ I E G V + + S + I G V + KQ L L++ Q + T
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180
Query: 730 VDIRAKP 736
+ + P
Sbjct: 181 IPYQPMP 187
Score = 42.0 bits (97), Expect = 0.004
Identities = 39/164 (23%), Positives = 71/164 (43%), Gaps = 23/164 (14%)
Query: 1067 IIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQ 1126
IIG+KG + +IR E I +GN P+ IT+TG T A A I+ +LE+
Sbjct: 28 IIGKKGESVKRIREESGARINI---SEGNCPERIITLTG---PTNAIFKAFAMIIDKLEE 81
Query: 1127 MVSEDV---------PLDHRVHA------RIIGARGKAIRKIMDEFKVDIRFPQSGAPDP 1171
++ + P+ R+ +IG G I++I + ++ P+
Sbjct: 82 DINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNS 141
Query: 1172 N--CVTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKP 1213
+T+ G+P++V E + I + E L+ + + +P
Sbjct: 142 TERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQP 185
Score = 40.8 bits (94), Expect = 0.008
Identities = 33/135 (24%), Positives = 56/135 (41%), Gaps = 14/135 (10%)
Query: 237 IAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEE------ 290
I G V I +E+G RINI + I TG + +A A I EE
Sbjct: 28 IIGKKGESVKRIREESGARINISEGNCPERIITLTGPTNAIFKAFAMIIDKLEEDINSSM 87
Query: 291 -----KKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPS---DSISETVI 342
+ T+ + V +Q +IG G ++EI E TG V++ +S +
Sbjct: 88 TNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAIT 147
Query: 343 LRGEPEKLGQALTEV 357
+ G P+ + + + ++
Sbjct: 148 IAGVPQSVTECVKQI 162
Score = 39.7 bits (91), Expect = 0.018
Identities = 33/145 (22%), Positives = 65/145 (44%), Gaps = 5/145 (3%)
Query: 987 VIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKAGLLERVKE-LQAEQ 1045
+IG+KG ++++ +E I++ II +TG + +A A ++++++E + +
Sbjct: 28 IIGKKGESVKRIREESGARINISEGNCPERIITLTGPTNAIFKAFAMIIDKLEEDINSSM 87
Query: 1046 EDRALRS---FKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQIT 1102
+ S L + V +IG+ G I +IR +Q N + IT
Sbjct: 88 TNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAIT 147
Query: 1103 ITGYEKN-TEAARDAILRIVGELEQ 1126
I G ++ TE + L ++ L Q
Sbjct: 148 IAGVPQSVTECVKQICLVMLETLSQ 172
Score = 37.0 bits (84), Expect = 0.12
Identities = 26/139 (18%), Positives = 60/139 (43%), Gaps = 18/139 (12%)
Query: 98 GEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVA- 156
G++ + I + +GA + +S I ++G +A+ KA I+ +L+ ++++
Sbjct: 30 GKKGESVKRIREESGARINISEGNCPERIITLTGPTNAIFKAFAMIIDKLEEDINSSMTN 89
Query: 157 --------------IPKEHHRFVIGKNGEKLQDLELKTATKIQIP---RPDDPSNQIKIT 199
+P +IGK G K++++ T ++Q+ P+ I I
Sbjct: 90 STAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIA 149
Query: 200 GTKEGIEKARHEVLLISAE 218
G + + + ++ L+ E
Sbjct: 150 GVPQSVTECVKQICLVMLE 168
Score = 32.7 bits (73), Expect = 2.3
Identities = 29/146 (19%), Positives = 62/146 (42%), Gaps = 14/146 (9%)
Query: 450 LIGKSGANINRIKDQYKVSVRIPPDSEKSNLIRIEGDPQGVQQAKRELL-----ELASRM 504
+IGK G ++ RI+++ + I + +I + G + +A ++ ++ S M
Sbjct: 28 IIGKKGESVKRIREESGARINISEGNCPERIITLTGPTNAIFKAFAMIIDKLEEDINSSM 87
Query: 505 ENER-------TKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPD--PAQKSDIVQ 555
N T L++ ++IG+ G +I+EIR+ + D P +
Sbjct: 88 TNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAIT 147
Query: 556 LRGPKNEVEKCTKYMQKMVADLVENS 581
+ G V +C K + ++ + + S
Sbjct: 148 IAGVPQSVTECVKQICLVMLETLSQS 173
Score = 31.2 bits (69), Expect = 6.6
Identities = 17/64 (26%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Query: 149 TQASATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSN--QIKITGTKEGIE 206
TQ + + IP +IG+ G + ++ + +I+I P + S+ Q+ ITG+ I
Sbjct: 278 TQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASIS 337
Query: 207 KARH 210
A++
Sbjct: 338 LAQY 341
>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
Length = 361
Score = 50.1 bits (118), Expect = 1e-05
Identities = 85/384 (22%), Positives = 138/384 (35%), Gaps = 71/384 (18%)
Query: 573 MVADLVENSYSISVPIFKQFHK----NIIGKGGANIKKIREESNTKIDLPAENSNSETII 628
M ++E ++++ I H +IIGK G ++KK+REES +I++ N I
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 629 ITG-KRANCEAARSRILSIQKDLANI-----------AEVEVSIPAKLHNSLIGTKGRLI 676
+ G A +A I +++D+++ + + +PA SLIG G I
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 677 RSIMEECGG-VHIHFP-VEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRA 734
+ I E G V + + S + I G + + KQ+ + E K T+ R
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 735 KPEYHKFLIGKGGGKIRKVRDS------TGARVIFPAAEDKDQDLITIIGKEDAVREAQK 788
KP + G + DS T + + P E + TI G+ +
Sbjct: 181 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 240
Query: 789 ELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSDKVT 848
+L L HF + G SG +S
Sbjct: 241 KLHQLAM---------------QQSHFPMTHGNT---------------GFSGIESSSPE 270
Query: 849 LKGAKDCVEAAKKRIQEIIEDLEAQVTL-ECAIPQKFHRSVMGPKGSRIQQITRDFSVQI 907
+KG D AQ T E IP ++G +G++I +I + QI
Sbjct: 271 VKGYWGL-------------DASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQI 317
Query: 908 KFPDREENAVHSTEPVVQENGDEA 931
K + E ST+ V G A
Sbjct: 318 KIANPVEG---STDRQVTITGSAA 338
Score = 44.3 bits (103), Expect = 8e-04
Identities = 34/125 (27%), Positives = 61/125 (48%), Gaps = 15/125 (12%)
Query: 521 TIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKC----TKYMQKMVAD 576
+IIG+KGE ++++R++ IN + I+ L GP N + K +++ ++
Sbjct: 27 SIIGKKGESVKKMREE-SGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISS 85
Query: 577 LVENSYSISVP-------IFKQFHKNIIGKGGANIKKIREESNTKIDLPAE---NSNSET 626
+ NS + S P + ++IGKGG IK+IRE + ++ + + NS
Sbjct: 86 SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERA 145
Query: 627 IIITG 631
I I G
Sbjct: 146 ITIAG 150
Score = 38.5 bits (88), Expect = 0.041
Identities = 32/135 (23%), Positives = 56/135 (41%), Gaps = 14/135 (10%)
Query: 237 IAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEK----- 291
I G V ++ +E+G RINI + I G + +A A I EE
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSM 87
Query: 292 ------KKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPS---DSISETVI 342
+ T+ + V SQ +IG G ++EI E TG V++ +S +
Sbjct: 88 TNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAIT 147
Query: 343 LRGEPEKLGQALTEV 357
+ G P+ + + + ++
Sbjct: 148 IAGIPQSIIECVKQI 162
Score = 38.5 bits (88), Expect = 0.041
Identities = 29/123 (23%), Positives = 54/123 (43%), Gaps = 4/123 (3%)
Query: 987 VIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQE 1046
+IG+KG ++KM +E I++ II + G + +A A ++++++E +
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSM 87
Query: 1047 DRALRSFKLSVT----VDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQIT 1102
+ + + VT V +IG+ G I +IR +Q N + IT
Sbjct: 88 TNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAIT 147
Query: 1103 ITG 1105
I G
Sbjct: 148 IAG 150
Score = 37.4 bits (85), Expect = 0.092
Identities = 27/145 (18%), Positives = 63/145 (43%), Gaps = 18/145 (12%)
Query: 98 GEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVA- 156
G++ + ++ + +GA + +S I ++G +A+ KA I+ +L+ S+++
Sbjct: 30 GKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTN 89
Query: 157 --------------IPKEHHRFVIGKNGEKLQDLELKTATKIQIP---RPDDPSNQIKIT 199
+P +IGK G K++++ T ++Q+ P+ I I
Sbjct: 90 STAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIA 149
Query: 200 GTKEGIEKARHEVLLISAEQDKRAV 224
G + I + ++ ++ E + V
Sbjct: 150 GIPQSIIECVKQICVVMLESPPKGV 174
Score = 36.2 bits (82), Expect = 0.20
Identities = 35/136 (25%), Positives = 61/136 (44%), Gaps = 18/136 (13%)
Query: 379 IIGKKGQNLAKITQQMPKVHIEFTEG---EDKITLEGPTEDVNVAQEQI-EGMVKDLINR 434
IIGKKG+++ K+ ++ I +EG E ITL GPT + A I + + +D+ +
Sbjct: 28 IIGKKGESVKKMREESG-ARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSS 86
Query: 435 MDY----------VEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPD---SEKSNLI 481
M + + + LIGK G I I++ V++ D + I
Sbjct: 87 MTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAI 146
Query: 482 RIEGDPQGVQQAKREL 497
I G PQ + + +++
Sbjct: 147 TIAGIPQSIIECVKQI 162
Score = 33.9 bits (76), Expect = 1.0
Identities = 62/319 (19%), Positives = 121/319 (37%), Gaps = 57/319 (17%)
Query: 450 LIGKSGANINRIKDQYKVSVRIPPDSEKSNLIRIEGDPQGVQQAKRELLE-----LASRM 504
+IGK G ++ +++++ + I + +I + G + +A +++ ++S M
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSM 87
Query: 505 ENER-------TKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPD--PAQKSDIVQ 555
N T L++ ++IG+ G +I+EIR+ + D P +
Sbjct: 88 TNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAIT 147
Query: 556 LRGPKNEVEKCTKYMQKMVADLVENSYSISVPIF-KQFHKNIIGKGGANIKKIREES--- 611
+ G + +C K Q V L +++P K +I GG + +S
Sbjct: 148 IAGIPQSIIECVK--QICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASF 205
Query: 612 -----NTKIDLPAENSNSETIIITGKRANCEAARSRI--LSIQKD--------------- 649
+ ++ E E I G+ A + +++ L++Q+
Sbjct: 206 PHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIE 265
Query: 650 --------------LANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGG-VHIHFPVEG 694
A E++IP L +IG +G I I + G + I PVEG
Sbjct: 266 SSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEG 325
Query: 695 SGSDTVVIRGPSSDVEKAK 713
S V I G ++ + A+
Sbjct: 326 STDRQVTITGSAASISLAQ 344
Score = 33.5 bits (75), Expect = 1.3
Identities = 34/157 (21%), Positives = 60/157 (38%), Gaps = 17/157 (10%)
Query: 165 VIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQD---- 220
+IGK GE ++ + ++ +I I + P I + G I KA +++ E+D
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKA-FAMIIDKLEEDISSS 86
Query: 221 ---------KRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPP---PSVNRTEI 268
RL V + + G + EI + TG ++ + P+ I
Sbjct: 87 MTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAI 146
Query: 269 VFTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKS 305
G + + + V +I + E K TI K S
Sbjct: 147 TIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPS 183
Score = 30.8 bits (68), Expect = 8.6
Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 152 SATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPS--NQIKITGTKEGIEKAR 209
S + IP + +IG+ G K+ ++ + +I+I P + S Q+ ITG+ I A+
Sbjct: 285 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 344
Query: 210 H 210
+
Sbjct: 345 Y 345
>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
Length = 318
Score = 49.7 bits (117), Expect = 2e-05
Identities = 71/307 (23%), Positives = 121/307 (39%), Gaps = 72/307 (23%)
Query: 521 TIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKC----TKYMQKMVAD 576
+IIG+KGE ++++R++ IN + I+ L GP N + K +++ ++
Sbjct: 27 SIIGKKGESVKKMREE-SGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISS 85
Query: 577 LVENSYSISVP-------IFKQFHKNIIGKGGANIKKIREESNTKIDLPAE---NSNSET 626
+ NS + S P + ++IGKGG IK+IRE + ++ + + NS
Sbjct: 86 SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERA 145
Query: 627 IIITGKRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGV 686
I I G SI + + I V + P K GV
Sbjct: 146 ITIAGIPQ----------SIIECVKQICVVMLESPPK---------------------GV 174
Query: 687 HIHF-------PVEGSGSDTVVIRG----PSSDVEKAKKQLLHLAEEKQTKSFT-----V 730
I + PV +G I+G P D+ K + + + T T +
Sbjct: 175 TIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGL 234
Query: 731 DIRAKPEYHKF---------LIGKGGGKIRKVRDSTGARV-IFPAAEDKDQDLITIIGKE 780
D A+ H+ +IG+ G KI ++R +GA++ I E +TI G
Sbjct: 235 DASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSA 294
Query: 781 DAVREAQ 787
++ AQ
Sbjct: 295 ASISLAQ 301
Score = 48.5 bits (114), Expect = 4e-05
Identities = 47/192 (24%), Positives = 81/192 (42%), Gaps = 18/192 (9%)
Query: 573 MVADLVENSYSISVPIFKQFHK----NIIGKGGANIKKIREESNTKIDLPAENSNSETII 628
M ++E ++++ I H +IIGK G ++KK+REES +I++ N I
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 629 ITG-KRANCEAARSRILSIQKDLANI-----------AEVEVSIPAKLHNSLIGTKGRLI 676
+ G A +A I +++D+++ + + +PA SLIG G I
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 677 RSIMEECGG-VHIHFP-VEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRA 734
+ I E G V + + S + I G + + KQ+ + E K T+ R
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 735 KPEYHKFLIGKG 746
KP + G
Sbjct: 181 KPSSSPVIFAGG 192
Score = 48.1 bits (113), Expect = 5e-05
Identities = 38/137 (27%), Positives = 62/137 (45%), Gaps = 14/137 (10%)
Query: 667 SLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTK 726
S+IG KG ++ + EE G I+ + + GP++ + KA ++ EE +
Sbjct: 27 SIIGKKGESVKKMREE-SGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISS 85
Query: 727 SFTVDIRAK-----------PEYHKFLIGKGGGKIRKVRDSTGARVIFPA--AEDKDQDL 773
S T A LIGKGG KI+++R+STGA+V + +
Sbjct: 86 SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERA 145
Query: 774 ITIIGKEDAVREAQKEL 790
ITI G ++ E K++
Sbjct: 146 ITIAGIPQSIIECVKQI 162
Score = 44.3 bits (103), Expect = 8e-04
Identities = 61/293 (20%), Positives = 116/293 (39%), Gaps = 48/293 (16%)
Query: 450 LIGKSGANINRIKDQYKVSVRIPPDSEKSNLIRIEGDPQGVQQAKRELL-----ELASRM 504
+IGK G ++ +++++ + I + +I + G + +A ++ +++S M
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSM 87
Query: 505 ENER-------TKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPD--PAQKSDIVQ 555
N T L++ ++IG+ G +I+EIR+ + D P +
Sbjct: 88 TNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAIT 147
Query: 556 LRGPKNEVEKCTKYMQKMVADLVENSYSISVPIF-KQFHKNIIGKGG------------- 601
+ G + +C K Q V L +++P K +I GG
Sbjct: 148 IAGIPQSIIECVK--QICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQ 205
Query: 602 ANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIAEVEVSIP 661
++ K+ + + + P + N TG A +A+ A E++IP
Sbjct: 206 PDLTKLHQLAMQQSHFPMTHGN------TGFSAGLDAS-----------AQTTSHELTIP 248
Query: 662 AKLHNSLIGTKGRLIRSIMEECGG-VHIHFPVEGSGSDTVVIRGPSSDVEKAK 713
L +IG +G I I + G + I PVEGS V I G ++ + A+
Sbjct: 249 NDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 301
Score = 40.0 bits (92), Expect = 0.014
Identities = 53/299 (17%), Positives = 114/299 (38%), Gaps = 47/299 (15%)
Query: 98 GEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVA- 156
G++ + ++ + +GA + +S I ++G +A+ KA I+ +L+ S+++
Sbjct: 30 GKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTN 89
Query: 157 --------------IPKEHHRFVIGKNGEKLQDLELKTATKIQIP---RPDDPSNQIKIT 199
+P +IGK G K++++ T ++Q+ P+ I I
Sbjct: 90 STAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIA 149
Query: 200 GTKEGIEKARHEVLLISAEQDKRAVE---RLEVEKAFHPFIAGPYNRLVGEIMQETGTRI 256
G + I + ++ ++ E + V R + + F G + G+
Sbjct: 150 GIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYA------- 202
Query: 257 NIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYE--------EKKKKTTTIAVEVKKSQHK 308
IP P + + QLA + + + +TT+ + +
Sbjct: 203 -IPQPDLTKL--------HQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHELTIPNDLIG 253
Query: 309 YVIGPKGNSLQEILERTGVSVEI--PPSDSISETVILRGEPEKLGQALTEVYAKANSFT 365
+IG +G + EI + +G ++I P S V + G + A + + +S T
Sbjct: 254 CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 312
Score = 38.5 bits (88), Expect = 0.041
Identities = 29/123 (23%), Positives = 54/123 (43%), Gaps = 4/123 (3%)
Query: 987 VIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQE 1046
+IG+KG ++KM +E I++ II + G + +A A ++++++E +
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSM 87
Query: 1047 DRALRSFKLSVT----VDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQIT 1102
+ + + VT V +IG+ G I +IR +Q N + IT
Sbjct: 88 TNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAIT 147
Query: 1103 ITG 1105
I G
Sbjct: 148 IAG 150
Score = 36.6 bits (83), Expect = 0.16
Identities = 58/281 (20%), Positives = 111/281 (39%), Gaps = 31/281 (11%)
Query: 165 VIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQD---- 220
+IGK GE ++ + ++ +I I + P I + G I KA +++ E+D
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKA-FAMIIDKLEEDISSS 86
Query: 221 ---------KRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPP---PSVNRTEI 268
RL V + + G + EI + TG ++ + P+ I
Sbjct: 87 MTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAI 146
Query: 269 VFTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVI-GPKGNSLQEILERTGV 327
G + + + V +I + E K TI K S + G + ++Q
Sbjct: 147 TIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQ-----GQY 201
Query: 328 SVEIPPSDSISETVILRGE-PEKLGQALTEVYAKANSFTVS-SVAAPSWLHRFIIGKKGQ 385
++ P + + + + P G A++ T S + P+ L IIG++G
Sbjct: 202 AIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHELTIPNDLIGCIIGRQGA 261
Query: 386 NLAKITQQMPKVHIEF---TEG--EDKITLEGPTEDVNVAQ 421
+ +I +QM I+ EG + ++T+ G +++AQ
Sbjct: 262 KINEI-RQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 301
>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
Length = 331
Score = 48.5 bits (114), Expect = 4e-05
Identities = 47/192 (24%), Positives = 81/192 (42%), Gaps = 18/192 (9%)
Query: 573 MVADLVENSYSISVPIFKQFHK----NIIGKGGANIKKIREESNTKIDLPAENSNSETII 628
M ++E ++++ I H +IIGK G ++KK+REES +I++ N I
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 629 ITG-KRANCEAARSRILSIQKDLANI-----------AEVEVSIPAKLHNSLIGTKGRLI 676
+ G A +A I +++D+++ + + +PA SLIG G I
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 677 RSIMEECGG-VHIHFP-VEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRA 734
+ I E G V + + S + I G + + KQ+ + E K T+ R
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 735 KPEYHKFLIGKG 746
KP + G
Sbjct: 181 KPSSSPVIFAGG 192
Score = 48.1 bits (113), Expect = 5e-05
Identities = 38/137 (27%), Positives = 62/137 (45%), Gaps = 14/137 (10%)
Query: 667 SLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTK 726
S+IG KG ++ + EE G I+ + + GP++ + KA ++ EE +
Sbjct: 27 SIIGKKGESVKKMREE-SGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISS 85
Query: 727 SFTVDIRAK-----------PEYHKFLIGKGGGKIRKVRDSTGARVIFPA--AEDKDQDL 773
S T A LIGKGG KI+++R+STGA+V + +
Sbjct: 86 SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERA 145
Query: 774 ITIIGKEDAVREAQKEL 790
ITI G ++ E K++
Sbjct: 146 ITIAGIPQSIIECVKQI 162
Score = 47.4 bits (111), Expect = 9e-05
Identities = 65/294 (22%), Positives = 117/294 (39%), Gaps = 33/294 (11%)
Query: 521 TIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKC----TKYMQKMVAD 576
+IIG+KGE ++++R++ IN + I+ L GP N + K +++ ++
Sbjct: 27 SIIGKKGESVKKMREE-SGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISS 85
Query: 577 LVENSYSISVP-------IFKQFHKNIIGKGGANIKKIREESNTKIDLPAE---NSNSET 626
+ NS + S P + ++IGKGG IK+IRE + ++ + + NS
Sbjct: 86 SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERA 145
Query: 627 IIITGKRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIR--------- 677
I I G + +I + + P + +I G+
Sbjct: 146 ITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQ 205
Query: 678 ---SIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRA 734
+ + + HFP+ + I S +V K L QT S + I
Sbjct: 206 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEV---KGYWAGLDASAQTTSHELTI-- 260
Query: 735 KPEYHKFLIGKGGGKIRKVRDSTGARV-IFPAAEDKDQDLITIIGKEDAVREAQ 787
+ +IG+ G KI ++R +GA++ I E +TI G ++ AQ
Sbjct: 261 PNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 314
Score = 45.1 bits (105), Expect = 4e-04
Identities = 70/300 (23%), Positives = 119/300 (39%), Gaps = 51/300 (17%)
Query: 379 IIGKKGQNLAKITQQMPKVHIEFTEG---EDKITLEGPTEDVNVAQEQ-IEGMVKDLINR 434
IIGKKG+++ K+ ++ I +EG E ITL GPT + A I+ + +D+ +
Sbjct: 28 IIGKKGESVKKMREE-SGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSS 86
Query: 435 MD----------YVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPD---SEKSNLI 481
M + + + LIGK G I I++ V++ D + I
Sbjct: 87 MTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAI 146
Query: 482 RIEGDPQGVQQAKRE----LLELASR------MENERTKDLIIEQRFHRTIIGQ------ 525
I G PQ + + ++ +LE + + +I TI GQ
Sbjct: 147 TIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQP 206
Query: 526 ---KGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSY 582
K ++ + FP N +S +++G Y + A S+
Sbjct: 207 DLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKG----------YWAGLDASAQTTSH 256
Query: 583 SISVPIFKQFHKNIIGKGGANIKKIREESNTKIDL--PAENSNSETIIITGKRANCEAAR 640
+++P IIG+ GA I +IR+ S +I + P E S + ITG A+ A+
Sbjct: 257 ELTIP--NDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 314
Score = 43.1 bits (100), Expect = 0.002
Identities = 61/292 (20%), Positives = 110/292 (37%), Gaps = 39/292 (13%)
Query: 237 IAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEK----- 291
I G V ++ +E+G RINI + I G + +A A I EE
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSM 87
Query: 292 ------KKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPS---DSISETVI 342
+ T+ + V SQ +IG G ++EI E TG V++ +S +
Sbjct: 88 TNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAIT 147
Query: 343 LRGEPEKLGQALTEV-----YAKANSFTVSSVAAPSWLHRFIIGK-----KGQ------N 386
+ G P+ + + + ++ + T+ PS G +GQ +
Sbjct: 148 IAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPD 207
Query: 387 LAKITQ-QMPKVHIEFTEGEDKIT-LEGPTEDVNVAQEQIEGMVKDLINRMDYVEINIDH 444
L K+ Q M + H T G + +E + +V ++ + + E+ I +
Sbjct: 208 LTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSH-----ELTIPN 262
Query: 445 KFHRHLIGKSGANINRIKDQYKVSVRI--PPDSEKSNLIRIEGDPQGVQQAK 494
+IG+ GA IN I+ ++I P + + I G + A+
Sbjct: 263 DLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 314
Score = 42.4 bits (98), Expect = 0.003
Identities = 58/293 (19%), Positives = 117/293 (39%), Gaps = 35/293 (11%)
Query: 450 LIGKSGANINRIKDQYKVSVRIPPDSEKSNLIRIEGDPQGVQQAKRELL-----ELASRM 504
+IGK G ++ +++++ + I + +I + G + +A ++ +++S M
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSM 87
Query: 505 ENER-------TKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPD--PAQKSDIVQ 555
N T L++ ++IG+ G +I+EIR+ + D P +
Sbjct: 88 TNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAIT 147
Query: 556 LRGPKNEVEKCTKYMQKMVADLVENSYSISVPIF-KQFHKNIIGKGG------------- 601
+ G + +C K Q V L +++P K +I GG
Sbjct: 148 IAGIPQSIIECVK--QICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQ 205
Query: 602 ANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIAEVEVSIP 661
++ K+ + + + P + N+ +G ++ + + A E++IP
Sbjct: 206 PDLTKLHQLAMQQSHFPMTHGNTG---FSGIESSSPEVKGYWAGLDAS-AQTTSHELTIP 261
Query: 662 AKLHNSLIGTKGRLIRSIMEECGG-VHIHFPVEGSGSDTVVIRGPSSDVEKAK 713
L +IG +G I I + G + I PVEGS V I G ++ + A+
Sbjct: 262 NDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 314
Score = 38.5 bits (88), Expect = 0.041
Identities = 29/123 (23%), Positives = 54/123 (43%), Gaps = 4/123 (3%)
Query: 987 VIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQE 1046
+IG+KG ++KM +E I++ II + G + +A A ++++++E +
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSM 87
Query: 1047 DRALRSFKLSVT----VDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQIT 1102
+ + + VT V +IG+ G I +IR +Q N + IT
Sbjct: 88 TNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAIT 147
Query: 1103 ITG 1105
I G
Sbjct: 148 IAG 150
Score = 37.7 bits (86), Expect = 0.070
Identities = 49/296 (16%), Positives = 115/296 (38%), Gaps = 28/296 (9%)
Query: 98 GEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVA- 156
G++ + ++ + +GA + +S I ++G +A+ KA I+ +L+ S+++
Sbjct: 30 GKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTN 89
Query: 157 --------------IPKEHHRFVIGKNGEKLQDLELKTATKIQIP---RPDDPSNQIKIT 199
+P +IGK G K++++ T ++Q+ P+ I I
Sbjct: 90 STAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIA 149
Query: 200 GTKEGIEKARHEVLLISAEQDKRAVE---RLEVEKAFHPFIAGPYNRLVGEIMQETGTRI 256
G + I + ++ ++ E + V R + + F G + G+
Sbjct: 150 GIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLT 209
Query: 257 NIPPPSVNRTEIVFTGEK---EQLAQAVARIKKIYE--EKKKKTTTIAVEVKKSQHKYVI 311
+ ++ ++ T + + +K + + +TT+ + + +I
Sbjct: 210 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCII 269
Query: 312 GPKGNSLQEILERTGVSVEI--PPSDSISETVILRGEPEKLGQALTEVYAKANSFT 365
G +G + EI + +G ++I P S V + G + A + + +S T
Sbjct: 270 GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 325
Score = 33.5 bits (75), Expect = 1.3
Identities = 34/157 (21%), Positives = 60/157 (38%), Gaps = 17/157 (10%)
Query: 165 VIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQD---- 220
+IGK GE ++ + ++ +I I + P I + G I KA +++ E+D
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKA-FAMIIDKLEEDISSS 86
Query: 221 ---------KRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPP---PSVNRTEI 268
RL V + + G + EI + TG ++ + P+ I
Sbjct: 87 MTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAI 146
Query: 269 VFTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKS 305
G + + + V +I + E K TI K S
Sbjct: 147 TIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPS 183
>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
Length = 365
Score = 47.8 bits (112), Expect = 7e-05
Identities = 70/323 (21%), Positives = 130/323 (40%), Gaps = 57/323 (17%)
Query: 521 TIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKC----TKYMQKMVAD 576
+IIG+KGE ++++R++ IN + I+ L GP N + K +++ ++
Sbjct: 27 SIIGKKGESVKKMREE-SGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISS 85
Query: 577 LVENSYSISVP-------IFKQFHKNIIGKGGANIKKIREESNTKIDLPAE---NSNSET 626
+ NS + S P + ++IGKGG IK+IRE + ++ + + NS
Sbjct: 86 SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERA 145
Query: 627 IIITG-KRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNS-----LIGTKGRL----- 675
I I G ++ E + + + + L+ V+IP + S G + R
Sbjct: 146 ITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSD 205
Query: 676 IRSIMEECGGVHIHFPVEGSGSDTVVIRG----PSSDVEKAKKQLLHLAEEKQTKSFT-- 729
S + ++ +EG + I+G P D+ K + + + T T
Sbjct: 206 SASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGF 265
Query: 730 ---------------VDIRAKPEYHKF---------LIGKGGGKIRKVRDSTGARV-IFP 764
+D A+ H+ +IG+ G KI ++R +GA++ I
Sbjct: 266 SGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIAN 325
Query: 765 AAEDKDQDLITIIGKEDAVREAQ 787
E +TI G ++ AQ
Sbjct: 326 PVEGSTDRQVTITGSAASISLAQ 348
Score = 47.0 bits (110), Expect = 1e-04
Identities = 87/388 (22%), Positives = 140/388 (36%), Gaps = 75/388 (19%)
Query: 573 MVADLVENSYSISVPIFKQFHK----NIIGKGGANIKKIREESNTKIDLPAENSNSETII 628
M ++E ++++ I H +IIGK G ++KK+REES +I++ N I
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 629 ITG-KRANCEAARSRILSIQKDLANI-----------AEVEVSIPAKLHNSLIGTKGRLI 676
+ G A +A I +++D+++ + + +PA SLIG G I
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 677 RSIMEECGG-VHIHFP-VEGSGSDTVVIRG-PSSDVEKAKK---QLLHLAEEKQTKSFTV 730
+ I E G V + + S + I G P S +E K+ +L + K T+
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
Query: 731 DIRAKPEYHKFLIGKGGGKIRKVRDS------TGARVIFPAAEDKDQDLITIIGKEDAVR 784
R KP + G + DS T + + P E + TI G+ +
Sbjct: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
Query: 785 EAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQS 844
+L L HF + G SG +S
Sbjct: 241 PDLTKLHQLAM---------------QQSHFPMTHGNT---------------GFSGIES 270
Query: 845 DKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTL-ECAIPQKFHRSVMGPKGSRIQQITRDF 903
+KG D AQ T E IP ++G +G++I +I +
Sbjct: 271 SSPEVKGYWGL-------------DASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMS 317
Query: 904 SVQIKFPDREENAVHSTEPVVQENGDEA 931
QIK + E ST+ V G A
Sbjct: 318 GAQIKIANPVEG---STDRQVTITGSAA 342
Score = 40.4 bits (93), Expect = 0.011
Identities = 34/156 (21%), Positives = 68/156 (43%), Gaps = 5/156 (3%)
Query: 987 VIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQE 1046
+IG+KG ++KM +E I++ II + G + +A A ++++++E +
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSM 87
Query: 1047 DRALRSFKLSVT----VDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQIT 1102
+ + + VT V +IG+ G I +IR +Q N + IT
Sbjct: 88 TNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAIT 147
Query: 1103 ITGYEKN-TEAARDAILRIVGELEQMVSEDVPLDHR 1137
I G ++ E + + ++ L Q + V + +R
Sbjct: 148 IAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYR 183
Score = 39.3 bits (90), Expect = 0.024
Identities = 82/360 (22%), Positives = 134/360 (37%), Gaps = 64/360 (17%)
Query: 379 IIGKKGQNLAKITQQMPKVHIEFTEG---EDKITLEGPTEDVNVAQEQI-EGMVKDLINR 434
IIGKKG+++ K+ ++ I +EG E ITL GPT + A I + + +D+ +
Sbjct: 28 IIGKKGESVKKMREESG-ARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSS 86
Query: 435 MDY----------VEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPD---SEKSNLI 481
M + + + LIGK G I I++ V++ D + I
Sbjct: 87 MTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAI 146
Query: 482 RIEGDPQGVQQAKREL-LELASRMENERTKDLIIEQR---FHRTII---GQKGERIREIR 534
I G PQ + + +++ + + + K + I R +I GQ
Sbjct: 147 TIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDS 206
Query: 535 DKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHK 594
FP P D L GP E A ++ Y+I P + H+
Sbjct: 207 ASFPHTT---PSMCLNPD---LEGPPLE------------AYTIQGQYAIPQPDLTKLHQ 248
Query: 595 NIIGKGGANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIA 654
+ + + NT E+S+ E G A+ A
Sbjct: 249 LAMQQSHFPM----THGNTGFS-GIESSSPEVKGYWGLDAS---------------AQTT 288
Query: 655 EVEVSIPAKLHNSLIGTKGRLIRSIMEECGG-VHIHFPVEGSGSDTVVIRGPSSDVEKAK 713
E++IP L +IG +G I I + G + I PVEGS V I G ++ + A+
Sbjct: 289 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 348
Score = 38.5 bits (88), Expect = 0.041
Identities = 32/135 (23%), Positives = 56/135 (41%), Gaps = 14/135 (10%)
Query: 237 IAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEK----- 291
I G V ++ +E+G RINI + I G + +A A I EE
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSM 87
Query: 292 ------KKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPS---DSISETVI 342
+ T+ + V SQ +IG G ++EI E TG V++ +S +
Sbjct: 88 TNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAIT 147
Query: 343 LRGEPEKLGQALTEV 357
+ G P+ + + + ++
Sbjct: 148 IAGIPQSIIECVKQI 162
Score = 35.8 bits (81), Expect = 0.27
Identities = 26/139 (18%), Positives = 61/139 (43%), Gaps = 18/139 (12%)
Query: 98 GEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVA- 156
G++ + ++ + +GA + +S I ++G +A+ KA I+ +L+ S+++
Sbjct: 30 GKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTN 89
Query: 157 --------------IPKEHHRFVIGKNGEKLQDLELKTATKIQIP---RPDDPSNQIKIT 199
+P +IGK G K++++ T ++Q+ P+ I I
Sbjct: 90 STAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIA 149
Query: 200 GTKEGIEKARHEVLLISAE 218
G + I + ++ ++ E
Sbjct: 150 GIPQSIIECVKQICVVMLE 168
Score = 30.8 bits (68), Expect = 8.6
Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 152 SATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPS--NQIKITGTKEGIEKAR 209
S + IP + +IG+ G K+ ++ + +I+I P + S Q+ ITG+ I A+
Sbjct: 289 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 348
Query: 210 H 210
+
Sbjct: 349 Y 349
>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 47.4 bits (111), Expect = 9e-05
Identities = 87/388 (22%), Positives = 143/388 (36%), Gaps = 74/388 (19%)
Query: 573 MVADLVENSYSISVPIFKQFHK----NIIGKGGANIKKIREESNTKIDLPAENSNSETII 628
M ++E ++++ I H +IIGK G ++KK+REES +I++ N I
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 629 ITG-KRANCEAARSRILSIQKDLANI-----------AEVEVSIPAKLHNSLIGTKGRLI 676
+ G A +A I +++D+++ + + +PA SLIG G I
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 677 RSIMEECGG-VHIHFP-VEGSGSDTVVIRG-PSSDVEKAKK---QLLHLAEEKQTKSFTV 730
+ I E G V + + S + I G P S +E K+ +L + K T+
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
Query: 731 DIRAKPEYHKFLIGKGGGKIRKVRDS------TGARVIFPAAEDKDQDLITIIGKEDAVR 784
R KP + G + DS T + + P E + TI G+ +
Sbjct: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
Query: 785 EAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQS 844
+L L HF + G SG +S
Sbjct: 241 PDLTKLHQLAM---------------QQSHFPMTHGNT---------------GFSGIES 270
Query: 845 DKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTL-ECAIPQKFHRSVMGPKGSRIQQITRDF 903
+KG ++A+ AQ T E IP ++G +G++I +I +
Sbjct: 271 SSPEVKGYWAGLDAS------------AQTTSHELTIPNDLIGCIIGRQGAKINEIRQMS 318
Query: 904 SVQIKFPDREENAVHSTEPVVQENGDEA 931
QIK + E ST+ V G A
Sbjct: 319 GAQIKIANPVEG---STDRQVTITGSAA 343
Score = 47.4 bits (111), Expect = 9e-05
Identities = 70/324 (21%), Positives = 130/324 (40%), Gaps = 58/324 (17%)
Query: 521 TIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKC----TKYMQKMVAD 576
+IIG+KGE ++++R++ IN + I+ L GP N + K +++ ++
Sbjct: 27 SIIGKKGESVKKMREE-SGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISS 85
Query: 577 LVENSYSISVP-------IFKQFHKNIIGKGGANIKKIREESNTKIDLPAE---NSNSET 626
+ NS + S P + ++IGKGG IK+IRE + ++ + + NS
Sbjct: 86 SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERA 145
Query: 627 IIITG-KRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNS-----LIGTKGRL----- 675
I I G ++ E + + + + L+ V+IP + S G + R
Sbjct: 146 ITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSD 205
Query: 676 IRSIMEECGGVHIHFPVEGSGSDTVVIRG----PSSDVEKAKKQLLHLAEEKQTKSFT-- 729
S + ++ +EG + I+G P D+ K + + + T T
Sbjct: 206 SASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGF 265
Query: 730 ----------------VDIRAKPEYHKF---------LIGKGGGKIRKVRDSTGARV-IF 763
+D A+ H+ +IG+ G KI ++R +GA++ I
Sbjct: 266 SGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIA 325
Query: 764 PAAEDKDQDLITIIGKEDAVREAQ 787
E +TI G ++ AQ
Sbjct: 326 NPVEGSTDRQVTITGSAASISLAQ 349
Score = 41.6 bits (96), Expect = 0.005
Identities = 83/360 (23%), Positives = 137/360 (38%), Gaps = 63/360 (17%)
Query: 379 IIGKKGQNLAKITQQMPKVHIEFTEG---EDKITLEGPTEDVNVAQEQI-EGMVKDLINR 434
IIGKKG+++ K+ ++ I +EG E ITL GPT + A I + + +D+ +
Sbjct: 28 IIGKKGESVKKMREESG-ARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSS 86
Query: 435 MDY----------VEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPD---SEKSNLI 481
M + + + LIGK G I I++ V++ D + I
Sbjct: 87 MTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAI 146
Query: 482 RIEGDPQGVQQAKREL-LELASRMENERTKDLIIEQR---FHRTII---GQKGERIREIR 534
I G PQ + + +++ + + + K + I R +I GQ
Sbjct: 147 TIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDS 206
Query: 535 DKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHK 594
FP P D L GP E A ++ Y+I P + H+
Sbjct: 207 ASFPHTT---PSMCLNPD---LEGPPLE------------AYTIQGQYAIPQPDLTKLHQ 248
Query: 595 NIIGKGGANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIA 654
+ + + NT E+S+ E + G A +A+ A
Sbjct: 249 LAMQQSHFPM----THGNTGFS-GIESSSPE---VKGYWAGLDAS-----------AQTT 289
Query: 655 EVEVSIPAKLHNSLIGTKGRLIRSIMEECGG-VHIHFPVEGSGSDTVVIRGPSSDVEKAK 713
E++IP L +IG +G I I + G + I PVEGS V I G ++ + A+
Sbjct: 290 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 349
Score = 40.4 bits (93), Expect = 0.011
Identities = 34/156 (21%), Positives = 68/156 (43%), Gaps = 5/156 (3%)
Query: 987 VIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQE 1046
+IG+KG ++KM +E I++ II + G + +A A ++++++E +
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSM 87
Query: 1047 DRALRSFKLSVT----VDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQIT 1102
+ + + VT V +IG+ G I +IR +Q N + IT
Sbjct: 88 TNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAIT 147
Query: 1103 ITGYEKN-TEAARDAILRIVGELEQMVSEDVPLDHR 1137
I G ++ E + + ++ L Q + V + +R
Sbjct: 148 IAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYR 183
Score = 38.5 bits (88), Expect = 0.041
Identities = 32/135 (23%), Positives = 56/135 (41%), Gaps = 14/135 (10%)
Query: 237 IAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEK----- 291
I G V ++ +E+G RINI + I G + +A A I EE
Sbjct: 28 IIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSM 87
Query: 292 ------KKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPS---DSISETVI 342
+ T+ + V SQ +IG G ++EI E TG V++ +S +
Sbjct: 88 TNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAIT 147
Query: 343 LRGEPEKLGQALTEV 357
+ G P+ + + + ++
Sbjct: 148 IAGIPQSIIECVKQI 162
Score = 35.8 bits (81), Expect = 0.27
Identities = 26/139 (18%), Positives = 61/139 (43%), Gaps = 18/139 (12%)
Query: 98 GEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVA- 156
G++ + ++ + +GA + +S I ++G +A+ KA I+ +L+ S+++
Sbjct: 30 GKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTN 89
Query: 157 --------------IPKEHHRFVIGKNGEKLQDLELKTATKIQIP---RPDDPSNQIKIT 199
+P +IGK G K++++ T ++Q+ P+ I I
Sbjct: 90 STAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIA 149
Query: 200 GTKEGIEKARHEVLLISAE 218
G + I + ++ ++ E
Sbjct: 150 GIPQSIIECVKQICVVMLE 168
Score = 30.8 bits (68), Expect = 8.6
Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 152 SATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPS--NQIKITGTKEGIEKAR 209
S + IP + +IG+ G K+ ++ + +I+I P + S Q+ ITG+ I A+
Sbjct: 290 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 349
Query: 210 H 210
+
Sbjct: 350 Y 350
>gi|147902746 MEX3A protein [Homo sapiens]
Length = 520
Score = 47.0 bits (110), Expect = 1e-04
Identities = 48/196 (24%), Positives = 80/196 (40%), Gaps = 12/196 (6%)
Query: 838 PRSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFH-RSVMGPKGSRI 896
P + T KGA D A + E+ + T +P H ++G +G +I
Sbjct: 96 PAAQTPQPPTAPKGASDAKLCALYKEAELRLKGSSNTTECVPVPTSEHVAEIVGRQGCKI 155
Query: 897 QQITRDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGREAKDCDPGSPRRCDIIIISGR 956
+ + + IK P R E EPV G ++ + +I
Sbjct: 156 KALRAKTNTYIKTPVRGE------EPVFMVTGRREDVATARREIISAAEH---FSMIRAS 206
Query: 957 KEKCEAAKEALEALV-PVTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQS 1015
+ K AA AL VTI V VP+ + V+G KG+ I+++ + I P+ + +
Sbjct: 207 RNKSGAAFGVAPALPGQVTIRVRVPYRVVGLVVGPKGATIKRIQQQTNTYIITPSRD-RD 265
Query: 1016 DIIAITGLAANLDRAK 1031
+ ITG N++RA+
Sbjct: 266 PVFEITGAPGNVERAR 281
Score = 43.5 bits (101), Expect = 0.001
Identities = 39/183 (21%), Positives = 78/183 (42%), Gaps = 27/183 (14%)
Query: 561 NEVEKCTKYMQKMVADLVENSYSISVPIFKQFH-KNIIGKGGANIKKIREESNTKIDLPA 619
++ + C Y + + ++ + VP+ H I+G+ G IK +R ++NT I P
Sbjct: 111 SDAKLCALYKEAELRLKGSSNTTECVPVPTSEHVAEIVGRQGCKIKALRAKTNTYIKTPV 170
Query: 620 ENSNSETIIITGKRANCEAARSRILSIQKDLANI--------------------AEVEVS 659
++TG+R + AR I+S + + I + V
Sbjct: 171 -RGEEPVFMVTGRREDVATARREIISAAEHFSMIRASRNKSGAAFGVAPALPGQVTIRVR 229
Query: 660 IPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVV-IRGPSSDVEKAKKQL-L 717
+P ++ ++G KG I+ I ++ + + D V I G +VE+A++++
Sbjct: 230 VPYRVVGLVVGPKGATIKRIQQQ---TNTYIITPSRDRDPVFEITGAPGNVERAREEIET 286
Query: 718 HLA 720
H+A
Sbjct: 287 HIA 289
Score = 43.5 bits (101), Expect = 0.001
Identities = 37/143 (25%), Positives = 63/143 (44%), Gaps = 26/143 (18%)
Query: 141 KDIVARLQTQASATVAIP---KEHHRFVIGKNGEKLQDLELKTATKIQIP-RPDDPSNQI 196
K+ RL+ ++ T +P EH ++G+ G K++ L KT T I+ P R ++P
Sbjct: 120 KEAELRLKGSSNTTECVPVPTSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEP--VF 177
Query: 197 KITGTKEGIEKARHEVL-------LISAEQDK-------------RAVERLEVEKAFHPF 236
+TG +E + AR E++ +I A ++K + R+ V
Sbjct: 178 MVTGRREDVATARREIISAAEHFSMIRASRNKSGAAFGVAPALPGQVTIRVRVPYRVVGL 237
Query: 237 IAGPYNRLVGEIMQETGTRINIP 259
+ GP + I Q+T T I P
Sbjct: 238 VVGPKGATIKRIQQQTNTYIITP 260
Score = 37.0 bits (84), Expect = 0.12
Identities = 37/145 (25%), Positives = 62/145 (42%), Gaps = 26/145 (17%)
Query: 1066 KIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILR------ 1119
+I+GR+G I +R + + I+ P + G +P +TG ++ AR I+
Sbjct: 146 EIVGRQGCKIKALRAKTNTYIKTPVR--GEEPV--FMVTGRREDVATARREIISAAEHFS 201
Query: 1120 --------------IVGELEQMVSEDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQ 1165
+ L V+ V + +RV ++G +G I++I + I P
Sbjct: 202 MIRASRNKSGAAFGVAPALPGQVTIRVRVPYRVVGLVVGPKGATIKRIQQQTNTYIITP- 260
Query: 1166 SGAPDPNCVTVTGLPENVEEAIDHI 1190
S DP +TG P NVE A + I
Sbjct: 261 SRDRDP-VFEITGAPGNVERAREEI 284
>gi|165905613 ring finger and KH domain containing 1 [Homo sapiens]
Length = 651
Score = 45.4 bits (106), Expect = 3e-04
Identities = 35/156 (22%), Positives = 67/156 (42%), Gaps = 29/156 (18%)
Query: 586 VPIFKQFH-KNIIGKGGANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRIL 644
VP+ H I+G+ G IK +R ++NT I P I+TG++ + E A+ IL
Sbjct: 183 VPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPV-RGEEPVFIVTGRKEDVEMAKREIL 241
Query: 645 SIQK-----------------------DLANIAEVEVSIPAKLHNSLIGTKGRLIRSIME 681
S + +L ++V +P ++ ++G KG I+ I +
Sbjct: 242 SAAEHFSIIRATRSKAGGLPGAAQGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQ 301
Query: 682 ECGGVHIHFPVEGSGSDTV-VIRGPSSDVEKAKKQL 716
H + G + V + G +V++A++++
Sbjct: 302 R---THTYIVTPGRDKEPVFAVTGMPENVDRAREEI 334
Score = 43.1 bits (100), Expect = 0.002
Identities = 39/180 (21%), Positives = 80/180 (44%), Gaps = 28/180 (15%)
Query: 638 AARSRILSIQKDLANIAEVEVSIPAKLHNS-LIGTKGRLIRSIMEECGGVHIHFPVEGSG 696
A + ++ +K N+ E V +P+ H + ++G +G I+++ + +I PV G
Sbjct: 164 ADQMSVIGSRKKSVNMTEC-VPVPSSEHVAEIVGRQGCKIKALRAKTN-TYIKTPVRGE- 220
Query: 697 SDTVVIRGPSSDVEKAKKQLLHLAEE----KQTKS------------------FTVDIRA 734
++ G DVE AK+++L AE + T+S T+ +R
Sbjct: 221 EPVFIVTGRKEDVEMAKREILSAAEHFSIIRATRSKAGGLPGAAQGPPNLPGQTTIQVRV 280
Query: 735 KPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAEDKDQDLITIIGKEDAVREAQKELEALI 794
++G G I++++ T ++ P + + + + G + V A++E+EA I
Sbjct: 281 PYRVVGLVVGPKGATIKRIQQRTHTYIVTPGRD--KEPVFAVTGMPENVDRAREEIEAHI 338
Score = 42.7 bits (99), Expect = 0.002
Identities = 51/221 (23%), Positives = 82/221 (37%), Gaps = 57/221 (25%)
Query: 143 IVARLQTQASATVAIP---KEHHRFVIGKNGEKLQDLELKTATKIQIP-RPDDPSNQIKI 198
++ + + T +P EH ++G+ G K++ L KT T I+ P R ++P +
Sbjct: 169 VIGSRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEP--VFIV 226
Query: 199 TGTKEGIEKARHEVLLISAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINI 258
TG KE +E A+ E+L A E + +A G G
Sbjct: 227 TGRKEDVEMAKREIL--------SAAEHFSIIRATRSKAGGLPGAAQG------------ 266
Query: 259 PPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSL 318
PP++ TTI V V V+GPKG ++
Sbjct: 267 -PPNL-----------------------------PGQTTIQVRVPYRVVGLVVGPKGATI 296
Query: 319 QEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYA 359
+ I +RT + P D + G PE + +A E+ A
Sbjct: 297 KRIQQRTHTYIVTPGRDK-EPVFAVTGMPENVDRAREEIEA 336
Score = 40.0 bits (92), Expect = 0.014
Identities = 39/161 (24%), Positives = 69/161 (42%), Gaps = 16/161 (9%)
Query: 877 ECA-IPQKFH-RSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQENGDEAGEG 934
EC +P H ++G +G +I+ + + IK P R E EPV G +
Sbjct: 181 ECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGE------EPVFIVTGRKEDVE 234
Query: 935 REAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVPV----TIEVEVPFDLHRYVIGQ 990
++ + II + K A + + TI+V VP+ + V+G
Sbjct: 235 MAKREILSAAEH---FSIIRATRSKAGGLPGAAQGPPNLPGQTTIQVRVPYRVVGLVVGP 291
Query: 991 KGSGIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAK 1031
KG+ I+++ I P + + + A+TG+ N+DRA+
Sbjct: 292 KGATIKRIQQRTHTYIVTPGRD-KEPVFAVTGMPENVDRAR 331
Score = 38.1 bits (87), Expect = 0.054
Identities = 36/148 (24%), Positives = 61/148 (41%), Gaps = 29/148 (19%)
Query: 1066 KIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGE-- 1123
+I+GR+G I +R + + I+ P + G +P +TG +++ E A+ IL
Sbjct: 193 EIVGRQGCKIKALRAKTNTYIKTPVR--GEEPV--FIVTGRKEDVEMAKREILSAAEHFS 248
Query: 1124 ---------------------LEQMVSEDVPLDHRVHARIIGARGKAIRKIMDEFKVDIR 1162
L + V + +RV ++G +G I++I I
Sbjct: 249 IIRATRSKAGGLPGAAQGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQRTHTYIV 308
Query: 1163 FPQSGAPDPNCVTVTGLPENVEEAIDHI 1190
P G VTG+PENV+ A + I
Sbjct: 309 TP--GRDKEPVFAVTGMPENVDRAREEI 334
Score = 35.0 bits (79), Expect = 0.46
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 869 DLEAQVTLECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQENG 928
+L Q T++ +P + V+GPKG+ I++I + I P R++ V + + EN
Sbjct: 269 NLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQRTHTYIVTPGRDKEPVFAVTG-MPENV 327
Query: 929 DEAGEGREA 937
D A E EA
Sbjct: 328 DRAREEIEA 336
>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 43.9 bits (102), Expect = 0.001
Identities = 46/198 (23%), Positives = 81/198 (40%), Gaps = 39/198 (19%)
Query: 413 PTEDVNVAQEQIEGMVKDLINRMDYVEINI--DHKFHRHLIGKSGANINRIKDQYKVSVR 470
P ED+ Q K N + VE+ I K +IGK G NI ++ Y SV
Sbjct: 23 PAEDMEEEQA-----FKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVS 77
Query: 471 IPPDSEKSNLIRIEGDPQGVQQAKREL-------LELAS-------RMENERTK------ 510
+P S ++ I D + + + +++ L+L S +E++ +
Sbjct: 78 VPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQH 137
Query: 511 ----------DLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPD--PAQKSDIVQLRG 558
L+I Q IIG KG +I+E+R+ I F + P +V + G
Sbjct: 138 YKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGG 197
Query: 559 PKNEVEKCTKYMQKMVAD 576
+ V +C K + ++++
Sbjct: 198 KPDRVVECIKIILDLISE 215
Score = 43.5 bits (101), Expect = 0.001
Identities = 28/70 (40%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 586 VPIFKQFHKNIIGKGGANIKKIREES--NTKIDLPAENSNSETIIITGKRANCEAARSRI 643
V I K +IIGKGG IK+IR ES + KID P E S I ITG + + A+ +
Sbjct: 392 VTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLL 451
Query: 644 LSIQKDLANI 653
+ K A++
Sbjct: 452 QNSVKQYADV 461
Score = 38.5 bits (88), Expect = 0.041
Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Query: 742 LIGKGGGKIRKVRDSTGARV-IFPAAEDKDQDLITIIGKEDAVREAQKELEALIQNLDNV 800
+IGKGG +I+++R +GA + I E + +ITI G +D ++ AQ L+ ++ +V
Sbjct: 402 IIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYADV 461
Score = 37.7 bits (86), Expect = 0.070
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 653 IAEVEVSIPAKLHNSLIGTKGRLIRSIMEECG-GVHIHFPVEGSGSDTVVIRGPSSDVEK 711
I +V+IP L S+IG G+ I+ I E G + I P+EGS + I G ++
Sbjct: 387 IITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQN 446
Query: 712 AK 713
A+
Sbjct: 447 AQ 448
Score = 37.0 bits (84), Expect = 0.12
Identities = 19/58 (32%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Query: 155 VAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQ--IKITGTKEGIEKARH 210
V IPK+ +IGK G++++ + ++ I+I P + S I ITGT++ I+ A++
Sbjct: 392 VTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQY 449
Score = 35.0 bits (79), Expect = 0.46
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 17/73 (23%)
Query: 596 IIGKGGANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIAE 655
+IGKGG NIK +R + N + +P ++S E RILSI D+ I E
Sbjct: 57 VIGKGGKNIKALRTDYNASVSVP-DSSGPE----------------RILSISADIETIGE 99
Query: 656 VEVSIPAKLHNSL 668
+ I L L
Sbjct: 100 ILKKIIPTLEEGL 112
>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
[Homo sapiens]
Length = 463
Score = 43.9 bits (102), Expect = 0.001
Identities = 46/198 (23%), Positives = 81/198 (40%), Gaps = 39/198 (19%)
Query: 413 PTEDVNVAQEQIEGMVKDLINRMDYVEINI--DHKFHRHLIGKSGANINRIKDQYKVSVR 470
P ED+ Q K N + VE+ I K +IGK G NI ++ Y SV
Sbjct: 23 PAEDMEEEQA-----FKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVS 77
Query: 471 IPPDSEKSNLIRIEGDPQGVQQAKREL-------LELAS-------RMENERTK------ 510
+P S ++ I D + + + +++ L+L S +E++ +
Sbjct: 78 VPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQH 137
Query: 511 ----------DLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPD--PAQKSDIVQLRG 558
L+I Q IIG KG +I+E+R+ I F + P +V + G
Sbjct: 138 YKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGG 197
Query: 559 PKNEVEKCTKYMQKMVAD 576
+ V +C K + ++++
Sbjct: 198 KPDRVVECIKIILDLISE 215
Score = 41.6 bits (96), Expect = 0.005
Identities = 26/57 (45%), Positives = 32/57 (56%), Gaps = 2/57 (3%)
Query: 586 VPIFKQFHKNIIGKGGANIKKIREES--NTKIDLPAENSNSETIIITGKRANCEAAR 640
V I K +IIGKGG IK+IR ES + KID P E S I ITG + + A+
Sbjct: 392 VTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQ 448
Score = 39.7 bits (91), Expect = 0.018
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 1/77 (1%)
Query: 653 IAEVEVSIPAKLHNSLIGTKGRLIRSIMEECG-GVHIHFPVEGSGSDTVVIRGPSSDVEK 711
I +V+IP L S+IG G+ I+ I E G + I P+EGS + I G ++
Sbjct: 387 IITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQN 446
Query: 712 AKKQLLHLAEEKQTKSF 728
A+ L + ++ K F
Sbjct: 447 AQYLLQNSVKQYSGKFF 463
Score = 37.7 bits (86), Expect = 0.070
Identities = 19/51 (37%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
Query: 742 LIGKGGGKIRKVRDSTGARV-IFPAAEDKDQDLITIIGKEDAVREAQKELE 791
+IGKGG +I+++R +GA + I E + +ITI G +D ++ AQ L+
Sbjct: 402 IIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQ 452
Score = 37.0 bits (84), Expect = 0.12
Identities = 19/58 (32%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Query: 155 VAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQ--IKITGTKEGIEKARH 210
V IPK+ +IGK G++++ + ++ I+I P + S I ITGT++ I+ A++
Sbjct: 392 VTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQY 449
Score = 35.0 bits (79), Expect = 0.46
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 17/73 (23%)
Query: 596 IIGKGGANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIAE 655
+IGKGG NIK +R + N + +P ++S E RILSI D+ I E
Sbjct: 57 VIGKGGKNIKALRTDYNASVSVP-DSSGPE----------------RILSISADIETIGE 99
Query: 656 VEVSIPAKLHNSL 668
+ I L L
Sbjct: 100 ILKKIIPTLEEGL 112
>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 43.9 bits (102), Expect = 0.001
Identities = 46/198 (23%), Positives = 81/198 (40%), Gaps = 39/198 (19%)
Query: 413 PTEDVNVAQEQIEGMVKDLINRMDYVEINI--DHKFHRHLIGKSGANINRIKDQYKVSVR 470
P ED+ Q K N + VE+ I K +IGK G NI ++ Y SV
Sbjct: 23 PAEDMEEEQA-----FKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVS 77
Query: 471 IPPDSEKSNLIRIEGDPQGVQQAKREL-------LELAS-------RMENERTK------ 510
+P S ++ I D + + + +++ L+L S +E++ +
Sbjct: 78 VPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQH 137
Query: 511 ----------DLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPD--PAQKSDIVQLRG 558
L+I Q IIG KG +I+E+R+ I F + P +V + G
Sbjct: 138 YKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGG 197
Query: 559 PKNEVEKCTKYMQKMVAD 576
+ V +C K + ++++
Sbjct: 198 KPDRVVECIKIILDLISE 215
Score = 43.5 bits (101), Expect = 0.001
Identities = 28/70 (40%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 586 VPIFKQFHKNIIGKGGANIKKIREES--NTKIDLPAENSNSETIIITGKRANCEAARSRI 643
V I K +IIGKGG IK+IR ES + KID P E S I ITG + + A+ +
Sbjct: 392 VTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLL 451
Query: 644 LSIQKDLANI 653
+ K A++
Sbjct: 452 QNSVKQYADV 461
Score = 38.5 bits (88), Expect = 0.041
Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Query: 742 LIGKGGGKIRKVRDSTGARV-IFPAAEDKDQDLITIIGKEDAVREAQKELEALIQNLDNV 800
+IGKGG +I+++R +GA + I E + +ITI G +D ++ AQ L+ ++ +V
Sbjct: 402 IIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYADV 461
Score = 37.7 bits (86), Expect = 0.070
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 653 IAEVEVSIPAKLHNSLIGTKGRLIRSIMEECG-GVHIHFPVEGSGSDTVVIRGPSSDVEK 711
I +V+IP L S+IG G+ I+ I E G + I P+EGS + I G ++
Sbjct: 387 IITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQN 446
Query: 712 AK 713
A+
Sbjct: 447 AQ 448
Score = 37.0 bits (84), Expect = 0.12
Identities = 19/58 (32%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Query: 155 VAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQ--IKITGTKEGIEKARH 210
V IPK+ +IGK G++++ + ++ I+I P + S I ITGT++ I+ A++
Sbjct: 392 VTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQY 449
Score = 35.0 bits (79), Expect = 0.46
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 17/73 (23%)
Query: 596 IIGKGGANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIAE 655
+IGKGG NIK +R + N + +P ++S E RILSI D+ I E
Sbjct: 57 VIGKGGKNIKALRTDYNASVSVP-DSSGPE----------------RILSISADIETIGE 99
Query: 656 VEVSIPAKLHNSL 668
+ I L L
Sbjct: 100 ILKKIIPTLEEGL 112
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 42.7 bits (99), Expect = 0.002
Identities = 127/635 (20%), Positives = 253/635 (39%), Gaps = 96/635 (15%)
Query: 138 KARKDIVARLQTQASATVAIPKEHHRFVIGKNGEKLQDLEL------KTATKIQIPRPDD 191
K R+D+ Q AT A ++ H + + GE++ +L+ K +++++ D
Sbjct: 1177 KMRRDL-EEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDL 1235
Query: 192 PSNQIKITGTKEGIEKARHEV------LLISAEQDKRAVERLEVEKAFHPFIAGPYNRLV 245
SN ++ K +EK + + E+ +R + L ++A +G Y+R
Sbjct: 1236 ASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQ- 1294
Query: 246 GEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKS 305
+ E T ++ ++R + FT + E+L K+ EE+ K + +A ++ S
Sbjct: 1295 ---LDEKDTLVS----QLSRGKQAFTQQIEEL-------KRQLEEEIKAKSALAHALQSS 1340
Query: 306 QH-------KYVIGPKGNS-LQEILERTGVSV----EIPPSDSISETVILRGEPEKLGQA 353
+H +Y + + LQ + + V +D+I T L +KL Q
Sbjct: 1341 RHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400
Query: 354 LTE-------VYAKANSFTVSSVAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFTEGED 406
L + V AK S + + + +I + N A + + + E
Sbjct: 1401 LQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEW 1460
Query: 407 KITLEGPTEDVNVAQEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYK 466
K E ++ +Q++ + +L + E ++D + + N+ Q +
Sbjct: 1461 KQKCEETHAELEASQKESRSLSTELFKIKNAYEESLD---QLETLKRENKNL-----QQE 1512
Query: 467 VSVRIPPDSEKSNLI-RIEGDPQGVQQAKRELL----ELASRMENERTKDLIIEQRFHRT 521
+S +E I +E + V+Q K EL E + +E+E K L I+ ++
Sbjct: 1513 ISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQV 1572
Query: 522 ------IIGQKGERIREIRDKFPEVIINF-----PDPAQKSDIVQLR----GPKNEVEKC 566
I +K E I +++ ++ + + ++D ++L+ G NE+E
Sbjct: 1573 KSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQ 1632
Query: 567 TKYMQKMVADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSET 626
+ +M A+ + N Y + I K ++ + + +E+ ++ + +N
Sbjct: 1633 LNHANRMAAEALRN-YRNTQAILKDTQLHL-----DDALRSQEDLKEQLAMVERRANLLQ 1686
Query: 627 IIITGKRANCE-AARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGG 685
I RA E RSR ++ Q+ L A V + + SLI TK +L I +
Sbjct: 1687 AEIEELRATLEQTERSRKIAEQELLD--ASERVQLLHTQNTSLINTKKKLETDISQ---- 1740
Query: 686 VHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLA 720
++G D +I+ + EKAKK + A
Sbjct: 1741 ------IQGEMED--IIQEARNAEEKAKKAITDAA 1767
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,147,270
Number of Sequences: 37866
Number of extensions: 2134143
Number of successful extensions: 6580
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 70
Number of HSP's that attempted gapping in prelim test: 5481
Number of HSP's gapped (non-prelim): 641
length of query: 1268
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1154
effective length of database: 13,930,794
effective search space: 16076136276
effective search space used: 16076136276
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.