Guide to the Human Genome
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Search of human proteins with 4885185

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4885185 distal-less homeobox 3 [Homo sapiens]
         (287 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4885185 distal-less homeobox 3 [Homo sapiens]                      600   e-172
gi|4885187 distal-less homeobox 5 [Homo sapiens]                      259   2e-69
gi|4758168 distal-less homeobox 2 [Homo sapiens]                      216   1e-56
gi|82659115 distal-less homeobox 6 [Homo sapiens]                     139   4e-33
gi|64225290 distal-less homeobox 1 isoform 1 [Homo sapiens]           137   1e-32
gi|20143962 distal-less homeobox 4 isoform a [Homo sapiens]           124   1e-28
gi|20143960 distal-less homeobox 4 isoform b [Homo sapiens]           120   1e-27
gi|14149728 BarH-like homeobox 1 [Homo sapiens]                        86   4e-17
gi|6633798 BarH-like homeobox 2 [Homo sapiens]                         82   4e-16
gi|27886557 msh homeobox 2 [Homo sapiens]                              82   7e-16
gi|147901462 brain specific homeobox [Homo sapiens]                    79   4e-15
gi|118582284 msh homeobox 1 [Homo sapiens]                             79   5e-15
gi|210147470 NK2 transcription factor related, locus 6 [Homo sap...    79   5e-15
gi|39930383 BarH-like homeobox 2 [Homo sapiens]                        77   1e-14
gi|153218470 BarH-like homeobox 1 [Homo sapiens]                       77   2e-14
gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]    76   3e-14
gi|148746211 NK2 transcription factor related, locus 3 [Homo sap...    76   3e-14
gi|24497515 homeobox A3 isoform b [Homo sapiens]                       76   4e-14
gi|24497513 homeobox A3 isoform a [Homo sapiens]                       76   4e-14
gi|13562112 homeobox A3 isoform a [Homo sapiens]                       76   4e-14
gi|126116581 retina and anterior neural fold homeobox [Homo sapi...    74   1e-13
gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]                  73   3e-13
gi|5031761 homeobox A1 isoform a [Homo sapiens]                        73   3e-13
gi|70608170 H6 family homeobox 2 [Homo sapiens]                        72   4e-13
gi|4505401 NK2 transcription factor related, locus 2 [Homo sapiens]    72   4e-13
gi|226437602 NK1 homeobox 2 [Homo sapiens]                             72   6e-13
gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  72   6e-13
gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  72   6e-13
gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  72   6e-13
gi|7110735 ventral anterior homeobox 2 [Homo sapiens]                  72   6e-13

>gi|4885185 distal-less homeobox 3 [Homo sapiens]
          Length = 287

 Score =  600 bits (1548), Expect = e-172
 Identities = 287/287 (100%), Positives = 287/287 (100%)

Query: 1   MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESSVTDLGYYSAPQHDYYSGQPYGQTV 60
           MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESSVTDLGYYSAPQHDYYSGQPYGQTV
Sbjct: 1   MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESSVTDLGYYSAPQHDYYSGQPYGQTV 60

Query: 61  NPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYGAYREQPLPAQDPVSVKEEPEAEVR 120
           NPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYGAYREQPLPAQDPVSVKEEPEAEVR
Sbjct: 61  NPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYGAYREQPLPAQDPVSVKEEPEAEVR 120

Query: 121 MVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNR 180
           MVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNR
Sbjct: 121 MVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNR 180

Query: 181 RSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLPPPLPYSAS 240
           RSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLPPPLPYSAS
Sbjct: 181 RSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLPPPLPYSAS 240

Query: 241 PSYLDDPTNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPPNPGAVY 287
           PSYLDDPTNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPPNPGAVY
Sbjct: 241 PSYLDDPTNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPPNPGAVY 287


>gi|4885187 distal-less homeobox 5 [Homo sapiens]
          Length = 289

 Score =  259 bits (662), Expect = 2e-69
 Identities = 151/287 (52%), Positives = 184/287 (64%), Gaps = 21/287 (7%)

Query: 1   MSGSFDRKLSSILTD-----ISSSLSCHAGSKDSPTLPESSVTDLGYYS----APQHDYY 51
           M+G FDR++ SI +        +S + H  S++SPTLPESS TD  YYS    AP H Y 
Sbjct: 1   MTGVFDRRVPSIRSGDFQAPFQTSAAMHHPSQESPTLPESSATDSDYYSPTGGAP-HGYC 59

Query: 52  S--GQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYG-AYREQPLPAQDP 108
           S     YG+ +NPY Y +   +NG AG+      ++Y+Y +SY QYG AY   P     P
Sbjct: 60  SPTSASYGKALNPYQYQYH-GVNGSAGSYPAKAYADYSYASSYHQYGGAYNRVPSATNQP 118

Query: 109 VSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGL 168
              KE  E EVRMVNGKPKKVRKPRTIYSS+QLAALQRRFQK QYLALPERAELAA LGL
Sbjct: 119 E--KEVTEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGL 176

Query: 169 TQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPAR 228
           TQTQVKIWFQN+RSK KK+ KNGE+P EHSP++SD MACNSP SPA+W+    S      
Sbjct: 177 TQTQVKIWFQNKRSKIKKIMKNGEMPPEHSPSSSDPMACNSPQSPAVWEPQGSSRSLSHH 236

Query: 229 SQLPPPLP-YSASPSYLDDPTNSWYHAQNLSGPHLQQQPPQPATLHH 274
               PP    S + SYL++ + SWY +   +   +    P P +L H
Sbjct: 237 PHAHPPTSNQSPASSYLEN-SASWYTS---AASSINSHLPPPGSLQH 279


>gi|4758168 distal-less homeobox 2 [Homo sapiens]
          Length = 328

 Score =  216 bits (551), Expect = 1e-56
 Identities = 141/295 (47%), Positives = 170/295 (57%), Gaps = 32/295 (10%)

Query: 17  SSSLSCHAGSKDSPTLPESSVTDLGYYSAPQHDYYSGQPYGQTVNPYTY--HHQFNLNGL 74
           SSS S H   ++SPTLP S+ TD  YY+  QH    G   G   +PY +   +Q+  +GL
Sbjct: 42  SSSSSLHK-PQESPTLPVSTATDSSYYTNQQHPAGGGGGGG---SPYAHMGSYQYQASGL 97

Query: 75  AGTGAYSPKSEYTYG--ASYRQYGAYREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKP 132
                YS KS Y  G  A+Y  Y  Y     PA +    KE+ E E+R+VNGKPKKVRKP
Sbjct: 98  NNV-PYSAKSSYDLGYTAAYTSYAPYGTSSSPANNEPE-KEDLEPEIRIVNGKPKKVRKP 155

Query: 133 RTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGE 192
           RTIYSS+QLAALQRRFQK QYLALPERAELAA LGLTQTQVKIWFQNRRSKFKK++K+GE
Sbjct: 156 RTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKMWKSGE 215

Query: 193 VPLEHSPNNSDSMACNSPP--SPALWD------TSSHSTPAPARSQL--PPPLPYSASPS 242
           +P E  P  S S  C SPP  +PA WD       +    P    S        P SA+ +
Sbjct: 216 IPSEQHPGASASPPCASPPVSAPASWDFGVPQRMAGGGGPGSGGSGAGSSGSSPSSAASA 275

Query: 243 YLDDPTNSWYHAQNLSGPHLQ--------QQPPQP--ATLHHASPGPPPNPGAVY 287
           +L +    WYH  + S  HLQ         Q PQP     HH   G P + G ++
Sbjct: 276 FLGN--YPWYHQTSGSASHLQATAPLLHPTQTPQPHHHHHHHGGGGAPVSAGTIF 328


>gi|82659115 distal-less homeobox 6 [Homo sapiens]
          Length = 265

 Score =  139 bits (349), Expect = 4e-33
 Identities = 101/240 (42%), Positives = 123/240 (51%), Gaps = 35/240 (14%)

Query: 46  PQHDYYSGQPYGQTVNPYTYHHQFNLNGL----AGTGAYSPKSEYTYG-ASYRQYG---- 96
           P H  +S        + + +HHQ + +G      G  +Y+ +S   Y   S+ Q+     
Sbjct: 42  PLHCLHSAAAAAAAGSHHHHHHQHHHHGSPYASGGGNSYNHRSLAAYPYMSHSQHSPYLQ 101

Query: 97  AYREQPLPAQ------DPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQK 150
           +Y      AQ      D          E+R  NGK KK+RKPRTIYSS QL AL  RFQ+
Sbjct: 102 SYHNSSAAAQTRGDDTDQQKTTVIENGEIRF-NGKGKKIRKPRTIYSSLQLQALNHRFQQ 160

Query: 151 AQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSP-NNSDSMACNS 209
            QYLALPERAELAA LGLTQTQVKIWFQN+RSKFKKL K G  P E  P   S +++  S
Sbjct: 161 TQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLKQGSNPHESDPLQGSAALSPRS 220

Query: 210 PPSPALWDTSSHSTPAPARSQLPPPLPYSASPSYLDDPTNSWYHAQNLSGPHLQ-QQPPQ 268
           P  P +WD S     A A+    PP  Y   P Y     + WY     S PH    Q PQ
Sbjct: 221 PALPPVWDVS-----ASAKGVSMPPNSY--MPGY-----SHWY-----SSPHQDTMQRPQ 263


>gi|64225290 distal-less homeobox 1 isoform 1 [Homo sapiens]
          Length = 255

 Score =  137 bits (344), Expect = 1e-32
 Identities = 98/224 (43%), Positives = 120/224 (53%), Gaps = 23/224 (10%)

Query: 43  YSAPQHDYYSGQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYGAYREQP 102
           +S P   Y S   + +   P  Y +  +++  A +   S    Y   AS  Q  +  E P
Sbjct: 50  HSQPDGAYSSASSFSR---PLGYPYVNSVSSHASSPYISSVQSYPGSASLAQ--SRLEDP 104

Query: 103 LPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAEL 162
               +  +V E    EVR  NGK KK+RKPRTIYSS QL AL RRFQ+ QYLALPERAEL
Sbjct: 105 GADSEKSTVVEG--GEVRF-NGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAEL 161

Query: 163 AAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSP-NNSDSMACNSPPSPALWDTSSH 221
           AA LGLTQTQVKIWFQN+RSKFKKL K G   LE S   N  +++  SPP P  W+ +S 
Sbjct: 162 AASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGWNPNSS 221

Query: 222 STPAPARSQLPPPLPYSASPSYLDDPTNSWY---HAQNLSGPHL 262
           S      +        S  PSY      SWY   H + +  P L
Sbjct: 222 SGKGSGGN------AGSYIPSY-----TSWYPSAHQEAMQQPQL 254


>gi|20143962 distal-less homeobox 4 isoform a [Homo sapiens]
          Length = 240

 Score =  124 bits (311), Expect = 1e-28
 Identities = 83/179 (46%), Positives = 98/179 (54%), Gaps = 28/179 (15%)

Query: 73  GLAGTGAYSPKSEYTY----------------GASYR--QYGAYREQPL--PAQDPVSVK 112
           GL+ T A SP   Y+                 G SY   Q  A   QPL  PA+ P  ++
Sbjct: 34  GLSPTTAASPNLSYSRPYGHLLSYPYTEPANPGDSYLSCQQPAALSQPLCGPAEHPQELE 93

Query: 113 EE-------PEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQ 165
            +       PE   R      KK+RKPRTIYSS QL  L +RFQ  QYLALPERA+LAAQ
Sbjct: 94  ADSEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQ 153

Query: 166 LGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHS-PNNSDSMACNSPPSPALWDTSSHST 223
           LGLTQTQVKIWFQN+RSK+KKL K      E   P  + S++  SPP P+LWD     T
Sbjct: 154 LGLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGT 212


>gi|20143960 distal-less homeobox 4 isoform b [Homo sapiens]
          Length = 168

 Score =  120 bits (302), Expect = 1e-27
 Identities = 65/110 (59%), Positives = 74/110 (67%), Gaps = 1/110 (0%)

Query: 115 PEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVK 174
           PE   R      KK+RKPRTIYSS QL  L +RFQ  QYLALPERA+LAAQLGLTQTQVK
Sbjct: 31  PEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVK 90

Query: 175 IWFQNRRSKFKKLYKNGEVPLEHS-PNNSDSMACNSPPSPALWDTSSHST 223
           IWFQN+RSK+KKL K      E   P  + S++  SPP P+LWD     T
Sbjct: 91  IWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGT 140


>gi|14149728 BarH-like homeobox 1 [Homo sapiens]
          Length = 327

 Score = 85.9 bits (211), Expect = 4e-17
 Identities = 58/159 (36%), Positives = 78/159 (49%), Gaps = 33/159 (20%)

Query: 111 VKEEPEAEVRMVNGKP----KKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQL 166
           VKEE + E+      P    KK RK RT ++ +QLA L+R F++ +YL++ +R ELAA L
Sbjct: 156 VKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASL 215

Query: 167 GLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNS-------------DSMACNSPPSP 213
            LT TQVK W+QNRR+K+K+    G   L  + N S              S+  N  P  
Sbjct: 216 NLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGA 275

Query: 214 ALWDTSSHSTPAPA----------------RSQLPPPLP 236
           AL+     S P PA                 S+ PPPLP
Sbjct: 276 ALYLYRGPSAPPPALQRPLVPRILIHGLQGASEPPPPLP 314



 Score = 33.5 bits (75), Expect = 0.22
 Identities = 31/94 (32%), Positives = 37/94 (39%), Gaps = 5/94 (5%)

Query: 194 PLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLPPPLPYSASPSYLDDPTNS-WY 252
           PLE SP +  S  C+SP SP   D     TP P  +   P L     P  L  P  S   
Sbjct: 35  PLELSPRSESSSDCSSPASPGR-DCLETGTPRPGGAS-GPGLDSHLQPGQLSAPAQSRTV 92

Query: 253 HAQNLSGPHLQQQPPQPATLHHASPGPP--PNPG 284
            +  L    L    P  A   ++S G P  P PG
Sbjct: 93  TSSFLIRDILADCKPLAACAPYSSSGQPAAPEPG 126


>gi|6633798 BarH-like homeobox 2 [Homo sapiens]
          Length = 279

 Score = 82.4 bits (202), Expect = 4e-16
 Identities = 55/171 (32%), Positives = 78/171 (45%), Gaps = 18/171 (10%)

Query: 116 EAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKI 175
           E+E      + KK R+ RTI++  QL  L+++FQK +YL+ P+R +LA  LGLTQ QVK 
Sbjct: 120 ESETEQPTPRQKKPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKT 179

Query: 176 WFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLPP-- 233
           W+QNRR K+KK+   G       P        + P S  +      ++ A  + QL P  
Sbjct: 180 WYQNRRMKWKKMVLKGGQEAPTKPKGRPKKN-SIPTSEEIEAEEKMNSQAQGQEQLEPSQ 238

Query: 234 ---PLPYSASPSYLDDPTNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPP 281
               L  +  P   D P              + + P  P  L   S  PPP
Sbjct: 239 GQEELCEAQEPKARDVPL------------EMAEPPDPPQELPIPSSEPPP 277


>gi|27886557 msh homeobox 2 [Homo sapiens]
          Length = 267

 Score = 81.6 bits (200), Expect = 7e-16
 Identities = 51/121 (42%), Positives = 73/121 (60%), Gaps = 4/121 (3%)

Query: 125 KPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKF 184
           K K  RKPRT +++ QL AL+R+F++ QYL++ ERAE ++ L LT+TQVKIWFQNRR+K 
Sbjct: 138 KHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKA 197

Query: 185 KKLYKN--GEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAP-ARSQLP-PPLPYSAS 240
           K+L +    ++ +   P    S +   P S  L   S +    P  R  LP PP+   A+
Sbjct: 198 KRLQEAELEKLKMAAKPMLPSSFSLPFPISSPLQAASIYGASYPFHRPVLPIPPVGLYAT 257

Query: 241 P 241
           P
Sbjct: 258 P 258


>gi|147901462 brain specific homeobox [Homo sapiens]
          Length = 233

 Score = 79.3 bits (194), Expect = 4e-15
 Identities = 55/152 (36%), Positives = 77/152 (50%), Gaps = 19/152 (12%)

Query: 115 PEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVK 174
           P  +   + GK  + RK RT++S  QL+ L++RF+  +YL+ PER ELA  L L++TQVK
Sbjct: 96  PHPQHAELPGKHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVK 155

Query: 175 IWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSH-STPAPARSQLPP 233
            WFQNRR K KK  +  +          +  A + P SP      S  +T A AR  LP 
Sbjct: 156 TWFQNRRMKHKKQLRKSQ---------DEPKAPDGPESPEGSPRGSEAATAAEARLSLP- 205

Query: 234 PLPYSASPSYLDDPTNS---WYHAQNLSGPHL 262
                A P  L +P +        +  SGPH+
Sbjct: 206 -----AGPFVLTEPEDEVDIGDEGELGSGPHV 232


>gi|118582284 msh homeobox 1 [Homo sapiens]
          Length = 303

 Score = 79.0 bits (193), Expect = 5e-15
 Identities = 37/63 (58%), Positives = 51/63 (80%)

Query: 125 KPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKF 184
           K K  RKPRT +++ QL AL+R+F++ QYL++ ERAE ++ L LT+TQVKIWFQNRR+K 
Sbjct: 168 KHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKA 227

Query: 185 KKL 187
           K+L
Sbjct: 228 KRL 230


>gi|210147470 NK2 transcription factor related, locus 6 [Homo
           sapiens]
          Length = 219

 Score = 79.0 bits (193), Expect = 5e-15
 Identities = 55/145 (37%), Positives = 73/145 (50%), Gaps = 14/145 (9%)

Query: 125 KPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKF 184
           K ++ RKPR ++S  Q+ AL+RRF++ +YL+ PER  LA+ L LT TQVKIWFQNRR K 
Sbjct: 46  KARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKC 105

Query: 185 KKLYKNGEVPLEHSPNNSDSMACNSPPSPAL-WDTSSHSTPAPARSQLPPPL-----PYS 238
           K+  ++  + L   P     +A      P L  D      P P     P P      PYS
Sbjct: 106 KRQRQDKSLELAGHPLTPRRVAV-----PVLVRDGKPCLGPGPGAPAFPSPYSAAVSPYS 160

Query: 239 ASPSYLDDPTNSWY---HAQNLSGP 260
               Y   P  + Y   +A   SGP
Sbjct: 161 CYGGYSGAPYGAGYGTCYAGAPSGP 185


>gi|39930383 BarH-like homeobox 2 [Homo sapiens]
          Length = 387

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 58/177 (32%), Positives = 82/177 (46%), Gaps = 23/177 (12%)

Query: 112 KEEPEAEVRMVNGKP----KKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLG 167
           KEE + E+      P    KK RK RT +S +QL  L+R F++ +YL++ +R +LAA L 
Sbjct: 211 KEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALN 270

Query: 168 LTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPP---SPALWDTSSHSTP 224
           LT TQVK W+QNRR+K+K+    G   L  + N S        P    P+L  +   +T 
Sbjct: 271 LTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDSTTA 330

Query: 225 APARSQLPPPLPYSASPSYLDDPTNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPP 281
           A A + +     YS           S Y       P LQ+       +H   PG  P
Sbjct: 331 AAAAAAM-----YS-----------SMYRTPPAPHPQLQRPLVPRVLIHGLGPGGQP 371


>gi|153218470 BarH-like homeobox 1 [Homo sapiens]
          Length = 254

 Score = 76.6 bits (187), Expect = 2e-14
 Identities = 34/67 (50%), Positives = 49/67 (73%)

Query: 125 KPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKF 184
           K KK R+ RT+++  QL  L++RF+K +YL+ P+R +LA  LGL+Q QVK W+QNRR K+
Sbjct: 138 KAKKGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKW 197

Query: 185 KKLYKNG 191
           KK+   G
Sbjct: 198 KKIVLQG 204


>gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]
          Length = 324

 Score = 76.3 bits (186), Expect = 3e-14
 Identities = 56/160 (35%), Positives = 82/160 (51%), Gaps = 21/160 (13%)

Query: 102 PLPAQDPVSVKEEPEAEVRMVN-----------GKPKKVRKPRTIYSSYQLAALQRRFQK 150
           P PA+DP + K+E  A  + V             + ++ RKPR ++S  Q+  L+RRF++
Sbjct: 100 PDPAKDPRAEKKELCALQKAVELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQ 159

Query: 151 AQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACN-- 208
            +YL+ PER +LA+ L LT TQVKIWFQNRR K K+  ++  + L   P      A    
Sbjct: 160 QRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIA 219

Query: 209 -----SPPSPALWDTSSHSTPAPARSQLPPPLPYSASPSY 243
                    P L D++ +   APA      P  Y+A P+Y
Sbjct: 220 VPVLVRDGKPCLGDSAPY---APAYGVGLNPYGYNAYPAY 256


>gi|148746211 NK2 transcription factor related, locus 3 [Homo
           sapiens]
          Length = 364

 Score = 76.3 bits (186), Expect = 3e-14
 Identities = 38/76 (50%), Positives = 53/76 (69%), Gaps = 1/76 (1%)

Query: 125 KPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKF 184
           KP+  RKPR ++S  Q+  L+RRF++ +YL+ PER  LA+ L LT TQVKIWFQNRR K 
Sbjct: 144 KPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKC 203

Query: 185 KKLYKNGEVPL-EHSP 199
           K+  ++  + L  H+P
Sbjct: 204 KRQRQDKSLELGAHAP 219


>gi|24497515 homeobox A3 isoform b [Homo sapiens]
          Length = 285

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 54/154 (35%), Positives = 71/154 (46%), Gaps = 22/154 (14%)

Query: 130 RKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYK 189
           ++ RT Y+S QL  L++ F   +YL  P R E+A  L LT+ Q+KIWFQNRR K+KK  K
Sbjct: 34  KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 93

Query: 190 NGEVPLEHSPNNSDSMACNSPPSPALWDTSSHS--TPAPARSQLPPPLPYSASPSYLDDP 247
            G+  L  S   S S +   PP    +  S HS     P   Q PPP       +Y   P
Sbjct: 94  -GKGMLTSSGGQSPSRS-PVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPP 151

Query: 248 TNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPP 281
            +                   PA+L   +P PPP
Sbjct: 152 AS------------------YPASLPSCAPPPPP 167


>gi|24497513 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 54/154 (35%), Positives = 71/154 (46%), Gaps = 22/154 (14%)

Query: 130 RKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYK 189
           ++ RT Y+S QL  L++ F   +YL  P R E+A  L LT+ Q+KIWFQNRR K+KK  K
Sbjct: 192 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 251

Query: 190 NGEVPLEHSPNNSDSMACNSPPSPALWDTSSHS--TPAPARSQLPPPLPYSASPSYLDDP 247
            G+  L  S   S S +   PP    +  S HS     P   Q PPP       +Y   P
Sbjct: 252 -GKGMLTSSGGQSPSRS-PVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPP 309

Query: 248 TNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPP 281
            +                   PA+L   +P PPP
Sbjct: 310 AS------------------YPASLPSCAPPPPP 325


>gi|13562112 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 54/154 (35%), Positives = 71/154 (46%), Gaps = 22/154 (14%)

Query: 130 RKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYK 189
           ++ RT Y+S QL  L++ F   +YL  P R E+A  L LT+ Q+KIWFQNRR K+KK  K
Sbjct: 192 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 251

Query: 190 NGEVPLEHSPNNSDSMACNSPPSPALWDTSSHS--TPAPARSQLPPPLPYSASPSYLDDP 247
            G+  L  S   S S +   PP    +  S HS     P   Q PPP       +Y   P
Sbjct: 252 -GKGMLTSSGGQSPSRS-PVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPP 309

Query: 248 TNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPP 281
            +                   PA+L   +P PPP
Sbjct: 310 AS------------------YPASLPSCAPPPPP 325


>gi|126116581 retina and anterior neural fold homeobox [Homo
           sapiens]
          Length = 346

 Score = 73.9 bits (180), Expect = 1e-13
 Identities = 70/225 (31%), Positives = 100/225 (44%), Gaps = 28/225 (12%)

Query: 79  AYSPKSEYTYGASY--RQYGAYREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIY 136
           A +P  EY     Y  ++ G  R  P     P +     EA++       KK R+ RT +
Sbjct: 88  APAPAPEYEAPRPYCPKEPGEARPSPGLPVGPAT----GEAKLSEEEQPKKKHRRNRTTF 143

Query: 137 SSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYK--NGEVP 194
           ++YQL  L+R F+K+ Y  +  R ELA ++ L + +V++WFQNRR+K+++  K     + 
Sbjct: 144 TTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKLEVSSMK 203

Query: 195 LEHSPNNSDSMACNSPPSPAL----WDTSSHSTPA----PARSQLPPPLPYSASPSYLDD 246
           L+ SP  S S    SPPS  L        S   PA    P  S L PPLP     + L  
Sbjct: 204 LQDSPLLSFS---RSPPSATLSPLGAGPGSGGGPAGGALPLESWLGPPLP-GGGATALQS 259

Query: 247 PTNSWYHAQNLSGPHLQQQPPQP--------ATLHHASPGPPPNP 283
                  AQ+L   +    PP P          L   +P PP  P
Sbjct: 260 LPGFGPPAQSLPASYTPPPPPPPFLNSPPLGPGLQPLAPPPPSYP 304


>gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 653

 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 55/180 (30%), Positives = 74/180 (41%), Gaps = 19/180 (10%)

Query: 123 NGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRS 182
           + K  K R+ RT ++  QL AL+ +F+  +YL++ ER  LA  L LT+TQVKIWFQNRR+
Sbjct: 91  DSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRT 150

Query: 183 KFKKLYKNGEVPLEHSPNNSDSMACN---------SP--PSPALWDTSSHSTPAPARSQL 231
           K+KK     +                         SP  PSP +        PA   +  
Sbjct: 151 KWKKQNPGADTSAPTGGGGGPGPGAGPGTGLPGGLSPLSPSPPMGAPLGMHGPAGYPAHG 210

Query: 232 PPPLPYSASPSYLDDPT--------NSWYHAQNLSGPHLQQQPPQPATLHHASPGPPPNP 283
           P  L  +A   +L  P         +  Y A     PHL    P         P P P P
Sbjct: 211 PGGLVCAAQLPFLSSPAVLSPFVLGSQTYGAPAFYAPHLLSPVPLXXXXXXXPPRPLPGP 270


>gi|5031761 homeobox A1 isoform a [Homo sapiens]
          Length = 335

 Score = 72.8 bits (177), Expect = 3e-13
 Identities = 64/205 (31%), Positives = 89/205 (43%), Gaps = 26/205 (12%)

Query: 41  GYYSAPQ---HDYYSGQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQY-- 95
           G  S+P    H ++ G   G   +P   HH +     +   A    S     AS+++   
Sbjct: 133 GNLSSPMVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACR 192

Query: 96  GAYREQPLPAQ--DPVSVKEEPEAEVRMVN----GKPKKVRKPRTIYSSYQLAALQRRFQ 149
               E   PAQ  D + VK  P    ++      G+P  VR   T +++ QL  L++ F 
Sbjct: 193 SPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVR---TNFTTKQLTELEKEFH 249

Query: 150 KAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPL------------EH 197
             +YL    R E+AA L L +TQVKIWFQNRR K KK  K G +P+            E 
Sbjct: 250 FNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDEKAEE 309

Query: 198 SPNNSDSMACNSPPSPALWDTSSHS 222
           S   S S  C   P  +  DT + S
Sbjct: 310 SSEKSSSSPCVPSPGSSTSDTLTTS 334


>gi|70608170 H6 family homeobox 2 [Homo sapiens]
          Length = 273

 Score = 72.4 bits (176), Expect = 4e-13
 Identities = 55/169 (32%), Positives = 79/169 (46%), Gaps = 6/169 (3%)

Query: 73  GLAGTGAYSPKSEYTYGASYRQYGAYREQPLPAQDPVSVKEEP-EAEVRMVNGKPKKVRK 131
           G  G+G    +       S+  +   +E+ LPA  P    E P +       G  KK  K
Sbjct: 94  GSGGSGPGGLERTPFLSPSHSDFKEEKERLLPAGSPSPGSERPRDGGAERQAGAAKK--K 151

Query: 132 PRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNG 191
            RT++S  Q+  L+  F   +YL+  ERA LA+ L LT+TQVK WFQNRR+K+K+   + 
Sbjct: 152 TRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKR-QLSA 210

Query: 192 EVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLPPPLPYSAS 240
           E+   +  + S     + P      D+S    P P     P PL Y  S
Sbjct: 211 ELEAANMAHASAQTLVSMP--LVFRDSSLLRVPVPRSLAFPAPLYYPGS 257


>gi|4505401 NK2 transcription factor related, locus 2 [Homo sapiens]
          Length = 273

 Score = 72.4 bits (176), Expect = 4e-13
 Identities = 49/137 (35%), Positives = 68/137 (49%), Gaps = 23/137 (16%)

Query: 56  YGQTVNPYTYHH------QFNLNGLAGTGAYSPKSEYTYGASYRQYGAYREQPLPAQDPV 109
           Y  + NPYT         Q++L+GLA             GA  +   +   +P   + P 
Sbjct: 66  YDSSDNPYTRWLASTEGLQYSLHGLAA------------GAPPQDSSSKSPEPSADESPD 113

Query: 110 SVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLT 169
           + KE P        G   K RK R ++S  Q   L+RRF++ +YL+ PER  LA+ + LT
Sbjct: 114 NDKETPGG-----GGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLT 168

Query: 170 QTQVKIWFQNRRSKFKK 186
            TQVKIWFQN R K K+
Sbjct: 169 PTQVKIWFQNHRYKMKR 185


>gi|226437602 NK1 homeobox 2 [Homo sapiens]
          Length = 310

 Score = 72.0 bits (175), Expect = 6e-13
 Identities = 36/83 (43%), Positives = 50/83 (60%)

Query: 104 PAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELA 163
           P + P      P    R +     K R+ RT ++  QL AL+ +F+  +YL++ ER  LA
Sbjct: 138 PVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLA 197

Query: 164 AQLGLTQTQVKIWFQNRRSKFKK 186
             L LT+TQVKIWFQNRR+K+KK
Sbjct: 198 LSLSLTETQVKIWFQNRRTKWKK 220


>gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 72.0 bits (175), Expect = 6e-13
 Identities = 36/83 (43%), Positives = 50/83 (60%)

Query: 104 PAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELA 163
           P + P      P    R +     K R+ RT ++  QL AL+ +F+  +YL++ ER  LA
Sbjct: 160 PVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLA 219

Query: 164 AQLGLTQTQVKIWFQNRRSKFKK 186
             L LT+TQVKIWFQNRR+K+KK
Sbjct: 220 LSLSLTETQVKIWFQNRRTKWKK 242


>gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 72.0 bits (175), Expect = 6e-13
 Identities = 36/83 (43%), Positives = 50/83 (60%)

Query: 104 PAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELA 163
           P + P      P    R +     K R+ RT ++  QL AL+ +F+  +YL++ ER  LA
Sbjct: 160 PVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLA 219

Query: 164 AQLGLTQTQVKIWFQNRRSKFKK 186
             L LT+TQVKIWFQNRR+K+KK
Sbjct: 220 LSLSLTETQVKIWFQNRRTKWKK 242


>gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 72.0 bits (175), Expect = 6e-13
 Identities = 36/83 (43%), Positives = 50/83 (60%)

Query: 104 PAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELA 163
           P + P      P    R +     K R+ RT ++  QL AL+ +F+  +YL++ ER  LA
Sbjct: 160 PVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLA 219

Query: 164 AQLGLTQTQVKIWFQNRRSKFKK 186
             L LT+TQVKIWFQNRR+K+KK
Sbjct: 220 LSLSLTETQVKIWFQNRRTKWKK 242


>gi|7110735 ventral anterior homeobox 2 [Homo sapiens]
          Length = 290

 Score = 72.0 bits (175), Expect = 6e-13
 Identities = 72/219 (32%), Positives = 101/219 (46%), Gaps = 25/219 (11%)

Query: 74  LAGTGAYSPKSEYTYGASYRQYGAYRE-QPLPAQDP----VSVKEEPEAEVRMVNGKPKK 128
           +AGT A SP       A  R+ GA  + QP P +      + V++       +V  K   
Sbjct: 46  VAGTSASSP-------AGSRESGADSDGQPGPGEADHCRRILVRDAKGTIREIVLPKGLD 98

Query: 129 VRKP---RTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFK 185
           + +P   RT +++ QL  L+  FQ+ QY+   ER ELA QL L++TQVK+WFQNRR+K K
Sbjct: 99  LDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQK 158

Query: 186 KLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLP-----PPLPYSAS 240
              K+    LE   ++S S A  +     L +     +   A S L      P LP S  
Sbjct: 159 ---KDQSRDLEKRASSSASEAFATSNILRLLEQGRLLSVPRAPSLLALTPSLPGLPASHR 215

Query: 241 PSYLDDPTNSWYHAQNLSGPHLQQ--QPPQPATLHHASP 277
            + L DP NS      LS         PP PA    ++P
Sbjct: 216 GTSLGDPRNSSPRLNPLSSASASPPLPPPLPAVCFSSAP 254


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.128    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,936,755
Number of Sequences: 37866
Number of extensions: 900162
Number of successful extensions: 6094
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 322
Number of HSP's successfully gapped in prelim test: 410
Number of HSP's that attempted gapping in prelim test: 4631
Number of HSP's gapped (non-prelim): 1693
length of query: 287
length of database: 18,247,518
effective HSP length: 101
effective length of query: 186
effective length of database: 14,423,052
effective search space: 2682687672
effective search space used: 2682687672
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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