Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 48675813
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|48675813 transportin 2 (importin 3, karyopherin beta 2b)
isoform 2 [Homo sapiens]
(887 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209969836 transportin 2 (importin 3, karyopherin beta 2b) iso... 1800 0.0
gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isof... 1800 0.0
gi|209969838 transportin 2 (importin 3, karyopherin beta 2b) iso... 1792 0.0
gi|23510381 transportin 1 isoform 2 [Homo sapiens] 1566 0.0
gi|133925811 transportin 1 isoform 1 [Homo sapiens] 1566 0.0
gi|19923142 karyopherin beta 1 [Homo sapiens] 120 6e-27
gi|24797086 importin 5 [Homo sapiens] 67 6e-11
gi|62460637 importin 4 [Homo sapiens] 66 1e-10
gi|45331213 RAN binding protein 6 [Homo sapiens] 65 2e-10
gi|198041777 Ran binding protein 11 isoform 1 [Homo sapiens] 47 6e-05
gi|39725950 Ran binding protein 11 isoform 2 [Homo sapiens] 47 6e-05
gi|21361659 importin 9 [Homo sapiens] 47 6e-05
gi|29029559 CSE1 chromosome segregation 1-like protein [Homo sap... 43 0.001
gi|122937211 KIAA0368 protein [Homo sapiens] 39 0.021
gi|4507943 exportin 1 [Homo sapiens] 38 0.048
gi|4504901 karyopherin alpha 4 [Homo sapiens] 38 0.048
gi|55956788 nucleolin [Homo sapiens] 37 0.062
gi|6912478 karyopherin alpha 6 [Homo sapiens] 37 0.081
gi|4507397 transcription factor 2 [Homo sapiens] 36 0.14
gi|54607053 GCN1 general control of amino-acid synthesis 1-like ... 36 0.14
gi|21361794 TIP120 protein [Homo sapiens] 36 0.18
gi|32455246 beta isoform of regulatory subunit A, protein phosph... 35 0.24
gi|32455244 beta isoform of regulatory subunit A, protein phosph... 35 0.24
gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription facto... 35 0.24
gi|154350213 hypothetical protein LOC79591 [Homo sapiens] 35 0.40
gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens] 34 0.69
gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens] 34 0.69
gi|89886480 zinedin isoform 2 [Homo sapiens] 34 0.69
gi|89886477 zinedin isoform 1 [Homo sapiens] 34 0.69
gi|54112117 splicing factor 3b, subunit 1 isoform 1 [Homo sapiens] 34 0.69
>gi|209969836 transportin 2 (importin 3, karyopherin beta 2b)
isoform 3 [Homo sapiens]
Length = 887
Score = 1800 bits (4662), Expect = 0.0
Identities = 887/887 (100%), Positives = 887/887 (100%)
Query: 1 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDE 60
MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDE
Sbjct: 1 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDE 60
Query: 61 PTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGE 120
PTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGE
Sbjct: 61 PTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGE 120
Query: 121 LQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQF 180
LQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQF
Sbjct: 121 LQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQF 180
Query: 181 FKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVML 240
FKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVML
Sbjct: 181 FKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVML 240
Query: 241 LEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIP 300
LEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIP
Sbjct: 241 LEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIP 300
Query: 301 ILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAED 360
ILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAED
Sbjct: 301 ILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAED 360
Query: 361 DDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA 420
DDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA
Sbjct: 361 DDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA 420
Query: 421 IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT 480
IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT
Sbjct: 421 IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT 480
Query: 481 ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD 540
ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD
Sbjct: 481 ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD 540
Query: 541 AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP 600
AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP
Sbjct: 541 AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP 600
Query: 601 YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV 660
YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV
Sbjct: 601 YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV 660
Query: 661 ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS 720
ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS
Sbjct: 661 ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS 720
Query: 721 VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCP 780
VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCP
Sbjct: 721 VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCP 780
Query: 781 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWV 840
QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWV
Sbjct: 781 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWV 840
Query: 841 SPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV 887
SPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV
Sbjct: 841 SPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV 887
>gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isoform
2 [Homo sapiens]
Length = 887
Score = 1800 bits (4662), Expect = 0.0
Identities = 887/887 (100%), Positives = 887/887 (100%)
Query: 1 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDE 60
MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDE
Sbjct: 1 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDE 60
Query: 61 PTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGE 120
PTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGE
Sbjct: 61 PTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGE 120
Query: 121 LQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQF 180
LQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQF
Sbjct: 121 LQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQF 180
Query: 181 FKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVML 240
FKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVML
Sbjct: 181 FKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVML 240
Query: 241 LEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIP 300
LEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIP
Sbjct: 241 LEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIP 300
Query: 301 ILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAED 360
ILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAED
Sbjct: 301 ILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAED 360
Query: 361 DDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA 420
DDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA
Sbjct: 361 DDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA 420
Query: 421 IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT 480
IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT
Sbjct: 421 IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT 480
Query: 481 ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD 540
ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD
Sbjct: 481 ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD 540
Query: 541 AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP 600
AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP
Sbjct: 541 AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP 600
Query: 601 YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV 660
YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV
Sbjct: 601 YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV 660
Query: 661 ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS 720
ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS
Sbjct: 661 ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS 720
Query: 721 VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCP 780
VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCP
Sbjct: 721 VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCP 780
Query: 781 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWV 840
QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWV
Sbjct: 781 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWV 840
Query: 841 SPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV 887
SPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV
Sbjct: 841 SPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV 887
>gi|209969838 transportin 2 (importin 3, karyopherin beta 2b)
isoform 1 [Homo sapiens]
Length = 897
Score = 1792 bits (4641), Expect = 0.0
Identities = 887/897 (98%), Positives = 887/897 (98%), Gaps = 10/897 (1%)
Query: 1 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDE 60
MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDE
Sbjct: 1 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDE 60
Query: 61 PTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGE 120
PTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGE
Sbjct: 61 PTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGE 120
Query: 121 LQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQF 180
LQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQF
Sbjct: 121 LQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQF 180
Query: 181 FKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVML 240
FKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVML
Sbjct: 181 FKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVML 240
Query: 241 LEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIP 300
LEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIP
Sbjct: 241 LEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIP 300
Query: 301 ILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAED 360
ILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAED
Sbjct: 301 ILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAED 360
Query: 361 DDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA 420
DDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA
Sbjct: 361 DDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA 420
Query: 421 IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT 480
IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT
Sbjct: 421 IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT 480
Query: 481 ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD 540
ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD
Sbjct: 481 ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD 540
Query: 541 AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP 600
AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP
Sbjct: 541 AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP 600
Query: 601 YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV 660
YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV
Sbjct: 601 YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV 660
Query: 661 ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS 720
ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS
Sbjct: 661 ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS 720
Query: 721 VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENT----------AI 770
VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENT AI
Sbjct: 721 VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTGRLTSPSAIPAI 780
Query: 771 TIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFI 830
TIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFI
Sbjct: 781 TIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFI 840
Query: 831 FFCDAVASWVSPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV 887
FFCDAVASWVSPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV
Sbjct: 841 FFCDAVASWVSPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV 897
>gi|23510381 transportin 1 isoform 2 [Homo sapiens]
Length = 890
Score = 1566 bits (4055), Expect = 0.0
Identities = 758/887 (85%), Positives = 830/887 (93%), Gaps = 1/887 (0%)
Query: 2 DWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDEP 61
+W+PDEQGLQQ+LQLLK+SQSP+T QR VQ KL+QLNQ+PDFNNYLIFVLT+LKSEDEP
Sbjct: 4 EWKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSEDEP 63
Query: 62 TRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGEL 121
TRSLSGLILKNNVKAH+Q+FP V DFIK ECLNNIGD+S LIRAT+GILITTIASKGEL
Sbjct: 64 TRSLSGLILKNNVKAHFQNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIASKGEL 123
Query: 122 QMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQFF 181
Q WP+LLP+LC+LL+SEDYNTCEGAFGALQKICEDS+E+LDSD L+RPLNIMIPKFLQFF
Sbjct: 124 QNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNIMIPKFLQFF 183
Query: 182 KHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVMLL 241
KH SPKIRSHA+ACVNQFI+ R QALM +ID+FIE+LFALA D++PEVRKNVCRALVMLL
Sbjct: 184 KHSSPKIRSHAVACVNQFIISRTQALMLHIDSFIENLFALAGDEEPEVRKNVCRALVMLL 243
Query: 242 EVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIPI 301
EVR+DRL+PHMH+I++YMLQRTQD DENVALEACEFWLTLAEQPICK+VL HL +LIP+
Sbjct: 244 EVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQPICKDVLVRHLPKLIPV 303
Query: 302 LVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAEDD 361
LVNGMKYS+IDIILLKGDVEEDE +PDSEQDI+PRFH+SRTV H+ + + +D +D+
Sbjct: 304 LVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHDEDGIEEEDDDDDE 363
Query: 362 -DDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA 420
DDDD +SDWNLRKCSAAALDVLANV+R+ELLPH+LPLLK LLFH EWVVKESGILVLGA
Sbjct: 364 IDDDDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLGA 423
Query: 421 IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT 480
IAEGCMQGM+PYLPELIPHLIQCLSDKKALVRSI CWTLSRYAHWVVSQPPD +LKPLMT
Sbjct: 424 IAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMT 483
Query: 481 ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD 540
ELLKRILD NKRVQEAACSAFATLEEEACTELVPYL+YILDTLVFAF KYQHKNLLILYD
Sbjct: 484 ELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYD 543
Query: 541 AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP 600
AIGTLADSVGHHLN+PEYIQ LMPPLIQKWN LKDEDKDLFPLLECLSSVATALQSGFLP
Sbjct: 544 AIGTLADSVGHHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECLSSVATALQSGFLP 603
Query: 601 YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV 660
YCEPVYQRCV LVQKTLAQAM+ P+QYEAPDKDFMIVALDLLSGLAEGLGG++EQLV
Sbjct: 604 YCEPVYQRCVNLVQKTLAQAMLNNAQPDQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLV 663
Query: 661 ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS 720
ARSNI+TL++QCMQD MPEVRQSSFALLGDLTKACF HVKPCIA+FMPILGTNLNPEFIS
Sbjct: 664 ARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPEFIS 723
Query: 721 VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCP 780
VCNNATWAIGEI +QMG EMQPY+ MVL+ LVEIINRPNTPKTLLENTAITIGRLGYVCP
Sbjct: 724 VCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIINRPNTPKTLLENTAITIGRLGYVCP 783
Query: 781 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWV 840
QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGIC MI VNP GV+QDFIFFCDAVASW+
Sbjct: 784 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMISVNPSGVIQDFIFFCDAVASWI 843
Query: 841 SPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV 887
+PKDDLRDMF KILHGFK+QVG++NW++FS+QFP LKERLAAFYGV
Sbjct: 844 NPKDDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAFYGV 890
>gi|133925811 transportin 1 isoform 1 [Homo sapiens]
Length = 898
Score = 1566 bits (4055), Expect = 0.0
Identities = 758/887 (85%), Positives = 830/887 (93%), Gaps = 1/887 (0%)
Query: 2 DWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDEP 61
+W+PDEQGLQQ+LQLLK+SQSP+T QR VQ KL+QLNQ+PDFNNYLIFVLT+LKSEDEP
Sbjct: 12 EWKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSEDEP 71
Query: 62 TRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGEL 121
TRSLSGLILKNNVKAH+Q+FP V DFIK ECLNNIGD+S LIRAT+GILITTIASKGEL
Sbjct: 72 TRSLSGLILKNNVKAHFQNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIASKGEL 131
Query: 122 QMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQFF 181
Q WP+LLP+LC+LL+SEDYNTCEGAFGALQKICEDS+E+LDSD L+RPLNIMIPKFLQFF
Sbjct: 132 QNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNIMIPKFLQFF 191
Query: 182 KHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVMLL 241
KH SPKIRSHA+ACVNQFI+ R QALM +ID+FIE+LFALA D++PEVRKNVCRALVMLL
Sbjct: 192 KHSSPKIRSHAVACVNQFIISRTQALMLHIDSFIENLFALAGDEEPEVRKNVCRALVMLL 251
Query: 242 EVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIPI 301
EVR+DRL+PHMH+I++YMLQRTQD DENVALEACEFWLTLAEQPICK+VL HL +LIP+
Sbjct: 252 EVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQPICKDVLVRHLPKLIPV 311
Query: 302 LVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAEDD 361
LVNGMKYS+IDIILLKGDVEEDE +PDSEQDI+PRFH+SRTV H+ + + +D +D+
Sbjct: 312 LVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHDEDGIEEEDDDDDE 371
Query: 362 -DDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA 420
DDDD +SDWNLRKCSAAALDVLANV+R+ELLPH+LPLLK LLFH EWVVKESGILVLGA
Sbjct: 372 IDDDDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLGA 431
Query: 421 IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT 480
IAEGCMQGM+PYLPELIPHLIQCLSDKKALVRSI CWTLSRYAHWVVSQPPD +LKPLMT
Sbjct: 432 IAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMT 491
Query: 481 ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD 540
ELLKRILD NKRVQEAACSAFATLEEEACTELVPYL+YILDTLVFAF KYQHKNLLILYD
Sbjct: 492 ELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYD 551
Query: 541 AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP 600
AIGTLADSVGHHLN+PEYIQ LMPPLIQKWN LKDEDKDLFPLLECLSSVATALQSGFLP
Sbjct: 552 AIGTLADSVGHHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECLSSVATALQSGFLP 611
Query: 601 YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV 660
YCEPVYQRCV LVQKTLAQAM+ P+QYEAPDKDFMIVALDLLSGLAEGLGG++EQLV
Sbjct: 612 YCEPVYQRCVNLVQKTLAQAMLNNAQPDQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLV 671
Query: 661 ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS 720
ARSNI+TL++QCMQD MPEVRQSSFALLGDLTKACF HVKPCIA+FMPILGTNLNPEFIS
Sbjct: 672 ARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPEFIS 731
Query: 721 VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCP 780
VCNNATWAIGEI +QMG EMQPY+ MVL+ LVEIINRPNTPKTLLENTAITIGRLGYVCP
Sbjct: 732 VCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIINRPNTPKTLLENTAITIGRLGYVCP 791
Query: 781 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWV 840
QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGIC MI VNP GV+QDFIFFCDAVASW+
Sbjct: 792 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMISVNPSGVIQDFIFFCDAVASWI 851
Query: 841 SPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV 887
+PKDDLRDMF KILHGFK+QVG++NW++FS+QFP LKERLAAFYGV
Sbjct: 852 NPKDDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAFYGV 898
>gi|19923142 karyopherin beta 1 [Homo sapiens]
Length = 876
Score = 120 bits (301), Expect = 6e-27
Identities = 172/794 (21%), Positives = 314/794 (39%), Gaps = 110/794 (13%)
Query: 12 QVLQLLKDSQSPNTATQRIVQDKLKQ--LNQFPDFNNYLIFVLTRLKSEDEPTRSLSGLI 69
+++ +L+ + SP+ Q L++ + P F L VL + R +GL
Sbjct: 2 ELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLAN-PGNSQVARVAAGLQ 60
Query: 70 LKNN-------VKAHYQ----SFPPPVADFIKQECLNNIGDA----SSLIRATIGILITT 114
+KN+ +KA YQ + +K L +G SS + GI
Sbjct: 61 IKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAE 120
Query: 115 IASKGELQMWPELLPQL-CNLLN-SEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNI 172
I + WPEL+PQL N+ N + + E A+ IC+D +D + L N
Sbjct: 121 IP----VNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQD----IDPEQLQDKSNE 172
Query: 173 MIPKFLQFFKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVD------DD 226
++ +Q + P + +A N +++ + N D E F + V D
Sbjct: 173 ILTAIIQGMRKEEPS-NNVKLAATNA-LLNSLEFTKANFDKESERHFIMQVVCEATQCPD 230
Query: 227 PEVRKNVCRALVMLLEVRIDRLIPHMH-SIIQYMLQRTQDHDENVALEACEFWLTLAEQP 285
VR + LV ++ + + +M ++ ++ + + VAL+ EFW + ++
Sbjct: 231 TRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDE- 289
Query: 286 ICKEVLASHLVQLIPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTL 345
E+D+ + + E P+ + K L
Sbjct: 290 ------------------------EMDLAIEASEAAEQGRPPEHTSKF---YAKGALQYL 322
Query: 346 PHEAERPDGSEDAEDDDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFH 405
+ +D DDDDD WN K + L +LA ++++PH+LP +K + +
Sbjct: 323 VPILTQTLTKQDENDDDDD-----WNPCKAAGVCLMLLATCCEDDIVPHVLPFIKEHIKN 377
Query: 406 PEWVVKESGILVLGAIAEGCMQGMV-PYLPELIPHLIQCLSDKKALVRSIACWTLSRYAH 464
P+W +++ ++ G I EG + P + + +P LI+ + D +VR A WT+ R
Sbjct: 378 PDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRICE 437
Query: 465 WVVSQP-PDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTL 523
+ D++L PL+ L++ L RV C AF++L EA E +
Sbjct: 438 LLPEAAINDVYLAPLLQCLIEG-LSAEPRVASNVCWAFSSL-AEAAYEAADVADDQEEPA 495
Query: 524 VFAFGKYQHKNLLILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPL 583
+ LI+ + T GH N + + ++ K+ KD +P
Sbjct: 496 TYCLSSSFE---LIVQKLLETTDRPDGHQNNLRSSAYESLMEIV------KNSAKDCYPA 546
Query: 584 LECLSSV-------ATALQSGFLPYCEPV-YQRCVTLVQKTLAQAMMYTQHPEQYEAPDK 635
++ + V ++S + + + +L+ TL + QH + + D
Sbjct: 547 VQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDALQISDV 606
Query: 636 DFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLL----FQCMQDSMP------------E 679
M L + A G + L+A S ++ +L + M+ P +
Sbjct: 607 -VMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKNYAEYQ 665
Query: 680 VRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFI--SVCNNATWAIGEICMQMG 737
V ++ L+GDL +A ++ P E M +L NL E + SV G+I + +G
Sbjct: 666 VCLAAVGLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDIALAIG 725
Query: 738 AEMQPYVQMVLNNL 751
E + Y+++VLN L
Sbjct: 726 GEFKKYLEVVLNTL 739
>gi|24797086 importin 5 [Homo sapiens]
Length = 1115
Score = 67.4 bits (163), Expect = 6e-11
Identities = 132/616 (21%), Positives = 243/616 (39%), Gaps = 88/616 (14%)
Query: 11 QQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSED--EPTRSLSGL 68
QQ LL + SP+ ++ ++ + + + + F+L +++ E R ++ +
Sbjct: 27 QQFYLLLGNLLSPDNVVRKQAEETYENIPG----QSKITFLLQAIRNTTAAEEARQMAAV 82
Query: 69 ILKNNVKAH----YQSFPPPVADFIKQECLNNIG--DASSLIRATIGI---LITTIASKG 119
+L+ + + Y + P V IK E L I SS+ + I L + +
Sbjct: 83 LLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQSSMRKKVCDIAAELARNLIDED 142
Query: 120 ELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKI--CEDSSELLDSDALNRPLNIMIPKF 177
WPE L L + ++S++ E A + + D + R M+ +
Sbjct: 143 GNNQWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIFGNQQQHYLDVIKR----MLVQC 198
Query: 178 LQFFKHCSPKIRSHAIACVNQFIM--DRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCR 235
+Q +H P IR+ + FI+ + AL + + D + +V +
Sbjct: 199 MQDQEH--PSIRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLK 256
Query: 236 ALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALE--ACEFWLTLAEQPICKEVLAS 293
+LV + + L PH+ + +Q L+ D N A E +TL+E +L
Sbjct: 257 SLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEVIVTLSETAAA--MLRK 314
Query: 294 H---LVQLIPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAE 350
H + Q IP ++ + D+EEDE +
Sbjct: 315 HTNIVAQTIP-----------QMLAMMVDLEEDE-------------------------D 338
Query: 351 RPDGSEDAEDDDDDDALSDWNLRKCSAAALDVLANVFREEL-LPHLLPLLKGLLFHPEWV 409
+ E +DD D +A++ +ALD +A +L LP + + +L +P+W
Sbjct: 339 WANADELEDDDFDSNAVA-------GESALDRMACGLGGKLVLPMIKEHIMQMLQNPDWK 391
Query: 410 VKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQ 469
+ +G++ L AI EGC Q M L E++ ++ L D VR AC + + A
Sbjct: 392 YRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPG 451
Query: 470 PPDMHLKPLMTELLKRILD-GNKRVQEAACSAFATLEEEACTE--LVPYL----SYILDT 522
+ ++ LL+ + D GN+RVQ A +A E+ C + L+PYL ++
Sbjct: 452 FQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTED-CPKSLLIPYLDNLVKHLHSI 510
Query: 523 LVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQP--EYIQKLMPPLIQKWNELKDEDKDL 580
+V + K ++ + + T SV + Y MP L ++ L
Sbjct: 511 MVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQKELRL 570
Query: 581 F--PLLECLSSVATAL 594
+EC+S + A+
Sbjct: 571 LRGKTIECISLIGLAV 586
>gi|62460637 importin 4 [Homo sapiens]
Length = 1081
Score = 66.2 bits (160), Expect = 1e-10
Identities = 102/438 (23%), Positives = 185/438 (42%), Gaps = 55/438 (12%)
Query: 349 AERPDGSEDAEDDDDDDALSDWNL-----RKCSAAALDVLA-NVFREELLPHLLPLLKGL 402
AE P G D ED D ++ + L + + +D+LA ++ E+L P L+P+L+
Sbjct: 301 AEPPPGQLDPEDQDSEEEELEIELMGETPKHFAVQVVDMLALHLPPEKLCPQLMPMLEEA 360
Query: 403 LFHPEWVVKESGILVLGAIAEGCMQGMVP-YLPELIPHLIQCLSDKKALVRSIACWTLSR 461
L +++G+LVL +++G + LP L+ + + L D +VR+ A + L +
Sbjct: 361 LRSESPYQRKAGLLVLAVLSDGAGDHIRQRLLPPLLQIVCKGLEDPSQVVRNAALFALGQ 420
Query: 462 YAHWVVSQPP----DMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLS 517
++ + QP + PL+ LK + G+ AC A E ++ PYL
Sbjct: 421 FSENL--QPHISSYSREVMPLLLAYLKSVPLGHTHHLAKACYALENFVENLGPKVQPYLP 478
Query: 518 YILDTLVFAF---GKYQHKNLLILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNE-L 573
+++ ++ + K L + A+G +A + L P +++ E L
Sbjct: 479 ELMECMLQLLRNPSSPRAKELAV--SALGAIATAAQASL------LPYFPAIMEHLREFL 530
Query: 574 KDEDKDLFPL----LECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQ 629
+DL P+ LE L +A A+ P E Q + L +Q
Sbjct: 531 LTGREDLQPVQIQSLETLGVLARAVGEPMRPLAEECCQLGLGLC--------------DQ 576
Query: 630 YEAPDKDFMIVAL-DLLSGL-AEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFAL 687
+ PD +L LSGL EGL H+EQ+ + +M L + + +P+ SS L
Sbjct: 577 VDDPDLRRCTYSLFAALSGLMGEGLAPHLEQI---TTLMLLSLRSTEGIVPQYDGSSSFL 633
Query: 688 LGDLTKACFIHVKPCIAEFMP------ILGTNLNPEFISVCNNATWAIGEICMQMGAEMQ 741
L D ++ + + E + I G ++ F + A+GEI +
Sbjct: 634 LFD-DESDGEEEEELMDEDVEEEDDSEISGYSVENAFFDEKEDTCAAVGEISVNTSVAFL 692
Query: 742 PYVQMVLNNLVEIINRPN 759
PY++ V + +++ P+
Sbjct: 693 PYMESVFEEVFKLLECPH 710
Score = 53.9 bits (128), Expect = 6e-07
Identities = 90/443 (20%), Positives = 186/443 (41%), Gaps = 48/443 (10%)
Query: 376 SAAALDVLANVFREELL---PHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPY 432
S + + A +FR+E L P LL LL+ P +E G+L+L + + P+
Sbjct: 97 SLSLAQLSATIFRKEGLEAWPQLLQLLQHSTHSPHSPEREMGLLLLSVVVTSRPEAFQPH 156
Query: 433 LPELIPHLIQCLSDKKA---LVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDG 489
EL+ L + L + + L S+ TL+ A ++ ++ D+ L ++ L +
Sbjct: 157 HRELLRLLNETLGEVGSPGLLFYSLR--TLTTMAPYLSTE--DVPLARMLVPKLIMAMQT 212
Query: 490 NKRVQEA-ACSAFATLEEEACTE---LVPYLSYILDTLV-----FAFGK-YQHKNLLILY 539
+ EA AC A L+E +E + PYLS +L + A G + + L L
Sbjct: 213 LIPIDEAKACEALEALDELLESEVPVITPYLSEVLTFCLEVARNVALGNAIRIRILCCLT 272
Query: 540 DAIGTLADSVGHHLNQPEYIQKLMP---------PLIQKWNELKDEDKDLFPLLECLSSV 590
+ + ++ + P + L P L + + ++E+ ++ + E
Sbjct: 273 FLVKVKSKALLKNRLLPPLLHTLFPIVAAEPPPGQLDPEDQDSEEEELEIELMGETPKHF 332
Query: 591 ATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAE 650
A + + P +K Q M + + E+P + L +L+ L++
Sbjct: 333 AVQVVDMLALHLPP---------EKLCPQLMPMLEEALRSESPYQ--RKAGLLVLAVLSD 381
Query: 651 GLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPIL 710
G G H+ Q + ++ ++ + ++D VR ++ LG ++ H+ E MP+L
Sbjct: 382 GAGDHIRQRLL-PPLLQIVCKGLEDPSQVVRNAALFALGQFSENLQPHISSYSREVMPLL 440
Query: 711 GTNLNPEFISVCNN---ATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLEN 767
L + ++ A +A+ +G ++QPY+ ++ +++++ P++P+
Sbjct: 441 LAYLKSVPLGHTHHLAKACYALENFVENLGPKVQPYLPELMECMLQLLRNPSSPRA---- 496
Query: 768 TAITIGRLGYVCPQEVAPMLQQF 790
+ + LG + A +L F
Sbjct: 497 KELAVSALGAIATAAQASLLPYF 519
>gi|45331213 RAN binding protein 6 [Homo sapiens]
Length = 1105
Score = 65.5 bits (158), Expect = 2e-10
Identities = 76/281 (27%), Positives = 124/281 (44%), Gaps = 49/281 (17%)
Query: 343 VTLPHEAERPDGSEDAEDDDDDDALSDWNLRKCSAAALDVLA-NVFREELLPHLLPLLKG 401
V L + + + E EDD D +A++ + +ALD LA + + +LP +
Sbjct: 321 VDLQDDEDWVNADEMEEDDFDSNAVA-------AESALDRLACGLGGKVVLPMTKEHIMQ 373
Query: 402 LLFHPEWVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSR 461
+L P+W + +G++ L AI EGC Q M L E + ++ L D VR+ AC TL +
Sbjct: 374 MLQSPDWKYRHAGLMALSAIGEGCHQQMESILDETVNSVLLFLQDPHPRVRAAACTTLGQ 433
Query: 462 YAHWVVSQPPDMHLKPLMTELLKRILD-GNKRVQEAACSAFATLEEEACTELVPYLSYIL 520
A + ++ LL+ + + GN+RVQ A SA E+
Sbjct: 434 MATDFAPNFQKKFHETVIAALLRTMENQGNQRVQSHAASALIIFIEDC------------ 481
Query: 521 DTLVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDL 580
K+LL+LY DS+ +L+ I+ + LI+ +L E
Sbjct: 482 -----------PKSLLVLY------VDSMVKNLHSVLVIK--LQELIRNGTKLALEQ--- 519
Query: 581 FPLLECLSSVATALQSGFLPYCE---PVYQRCVTL-VQKTL 617
L+ ++SVA ++ F+PY + P + V L VQK L
Sbjct: 520 --LVTTIASVADTIEEKFVPYYDIFMPSLKHIVELAVQKEL 558
Score = 32.7 bits (73), Expect = 1.5
Identities = 39/189 (20%), Positives = 74/189 (39%), Gaps = 23/189 (12%)
Query: 95 NNIGDASSLIRATIGILITTIASKGELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKIC 154
N + S+L R G+ G + P + +L S D+ AL I
Sbjct: 343 NAVAAESALDRLACGL--------GGKVVLPMTKEHIMQMLQSPDWKYRHAGLMALSAIG 394
Query: 155 EDSSELLDSDALNRPLNIMIPKFLQFFKHCSPKIRSHAIACVNQFIMDRAQALMDNI-DT 213
E + ++S L+ + L F + P++R+ A + Q D A +T
Sbjct: 395 EGCHQQMESI-----LDETVNSVLLFLQDPHPRVRAAACTTLGQMATDFAPNFQKKFHET 449
Query: 214 FIEHLF-ALAVDDDPEVRKNVCRALVMLLE--------VRIDRLIPHMHSIIQYMLQRTQ 264
I L + + V+ + AL++ +E + +D ++ ++HS++ LQ
Sbjct: 450 VIAALLRTMENQGNQRVQSHAASALIIFIEDCPKSLLVLYVDSMVKNLHSVLVIKLQELI 509
Query: 265 DHDENVALE 273
+ +ALE
Sbjct: 510 RNGTKLALE 518
Score = 30.0 bits (66), Expect = 9.9
Identities = 18/64 (28%), Positives = 31/64 (48%), Gaps = 2/64 (3%)
Query: 628 EQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFAL 687
+ ++PD + L LS + EG +E ++ + LLF +QD P VR ++
Sbjct: 373 QMLQSPDWKYRHAGLMALSAIGEGCHQQMESILDETVNSVLLF--LQDPHPRVRAAACTT 430
Query: 688 LGDL 691
LG +
Sbjct: 431 LGQM 434
>gi|198041777 Ran binding protein 11 isoform 1 [Homo sapiens]
Length = 1015
Score = 47.4 bits (111), Expect = 6e-05
Identities = 33/132 (25%), Positives = 61/132 (46%), Gaps = 6/132 (4%)
Query: 13 VLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDEPTRSLSGLILKN 72
VLQ+L + S +TA + +++LKQ P F + L+ + T + D R L+ L K+
Sbjct: 50 VLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTN-HTLDINVRWLAVLYFKH 108
Query: 73 NVKAHYQSFPPPVAD-----FIKQECLNNIGDASSLIRATIGILITTIASKGELQMWPEL 127
+ +++ P ++ + N + + I I +LI +A + WPEL
Sbjct: 109 GIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPEL 168
Query: 128 LPQLCNLLNSED 139
+P L + +D
Sbjct: 169 IPTLIESVKVQD 180
>gi|39725950 Ran binding protein 11 isoform 2 [Homo sapiens]
Length = 975
Score = 47.4 bits (111), Expect = 6e-05
Identities = 33/132 (25%), Positives = 61/132 (46%), Gaps = 6/132 (4%)
Query: 13 VLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDEPTRSLSGLILKN 72
VLQ+L + S +TA + +++LKQ P F + L+ + T + D R L+ L K+
Sbjct: 10 VLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTN-HTLDINVRWLAVLYFKH 68
Query: 73 NVKAHYQSFPPPVAD-----FIKQECLNNIGDASSLIRATIGILITTIASKGELQMWPEL 127
+ +++ P ++ + N + + I I +LI +A + WPEL
Sbjct: 69 GIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPEL 128
Query: 128 LPQLCNLLNSED 139
+P L + +D
Sbjct: 129 IPTLIESVKVQD 140
>gi|21361659 importin 9 [Homo sapiens]
Length = 1041
Score = 47.4 bits (111), Expect = 6e-05
Identities = 43/165 (26%), Positives = 75/165 (45%), Gaps = 11/165 (6%)
Query: 5 PDEQGLQQVL-QLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDEPTR 63
P QGL++ L L SP + ++++K L +F +L LT R
Sbjct: 16 PVAQGLKEALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLA-ELTVDPQGALAIR 74
Query: 64 SLSGLILKNNVKAHY----QSFPPPV----ADFIKQECL-NNIGDASSLIRATIGILITT 114
L+ +ILK V+ H+ + F PP A + +E L N + ++ S +R+++ ++
Sbjct: 75 QLASVILKQYVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSA 134
Query: 115 IASKGELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSE 159
IA + WP+L L +L S D N GA L + + ++
Sbjct: 135 IAHWDWPEAWPQLFNLLMEMLVSGDLNAVHGAMRVLTEFTREVTD 179
>gi|29029559 CSE1 chromosome segregation 1-like protein [Homo
sapiens]
Length = 971
Score = 43.1 bits (100), Expect = 0.001
Identities = 38/179 (21%), Positives = 77/179 (43%), Gaps = 11/179 (6%)
Query: 7 EQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRL-KSEDEPTRSL 65
+ LQ + + LK + P+ A +R + K L NY + +LT L KS+D +
Sbjct: 5 DANLQTLTEYLKKTLDPDPAIRRPAE---KFLESVEGNQNYPLLLLTLLEKSQDNVIKVC 61
Query: 66 SGLILKNNVKAHY---QSFPPPVADF----IKQECLNNIGDASSLIRATIGILITTIASK 118
+ + KN +K ++ + P + + IK ++ + + I+ + I+ I +
Sbjct: 62 ASVTFKNYIKRNWRIVEDEPNKICEADRVAIKANIVHLMLSSPEQIQKQLSDAISIIGRE 121
Query: 119 GELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKF 177
Q WP+LL ++ N S D++ G + + S+ L + +++ F
Sbjct: 122 DFPQKWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAF 180
>gi|122937211 KIAA0368 protein [Homo sapiens]
Length = 2017
Score = 38.9 bits (89), Expect = 0.021
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 12/144 (8%)
Query: 370 WNLRKCSAAALDVLANVFREEL---LPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCM 426
WN RK +A +V+A E+L LP L+P L F P ++++ + A+
Sbjct: 1267 WNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNALVTD-- 1324
Query: 427 QGMV-PYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPD--MHLKPLMTELL 483
+ MV YL E++ L++ L+ VR +C L+ +P D + P + E L
Sbjct: 1325 KSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLLR---GRPLDDIIDKLPEIWETL 1381
Query: 484 KRILDGNKR-VQEAACSAFATLEE 506
R+ D K V++AA A TL +
Sbjct: 1382 FRVQDDIKESVRKAAELALKTLSK 1405
Score = 37.7 bits (86), Expect = 0.048
Identities = 29/120 (24%), Positives = 51/120 (42%), Gaps = 3/120 (2%)
Query: 405 HPEWVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAH 464
H W ++ IA + + P+LP+L+P L + D +R T A
Sbjct: 1264 HAMWNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQ--AMTSIWNAL 1321
Query: 465 WVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAF-ATLEEEACTELVPYLSYILDTL 523
D +LK ++ +L+K + RV+E++C A L +++ L I +TL
Sbjct: 1322 VTDKSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLLRGRPLDDIIDKLPEIWETL 1381
Score = 36.2 bits (82), Expect = 0.14
Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 5/118 (4%)
Query: 392 LPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCL-----SD 446
L L+ + + L W +K G + + +IA+ + PYL ++ L+Q L +
Sbjct: 1697 LQELITITQKALQSQSWKMKAQGAIAMASIAKQTSSLVPPYLGMILTALLQGLAGRTWAG 1756
Query: 447 KKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATL 504
K+ L+++IAC + A S P ++ +LK N + + A S A +
Sbjct: 1757 KEELLKAIACVVTACSAELEKSVPNQPSTNEILQAVLKECSKENVKYKIVAISCAADI 1814
>gi|4507943 exportin 1 [Homo sapiens]
Length = 1071
Score = 37.7 bits (86), Expect = 0.048
Identities = 30/141 (21%), Positives = 61/141 (43%), Gaps = 20/141 (14%)
Query: 446 DKKALVRSIACWTLSRY-----AHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSA 500
D KA++ S + + +Y AHW LK ++ +L + + + + VQ+ AC
Sbjct: 535 DNKAIIASNIMYIVGQYPRFLRAHW-------KFLKTVVNKLFEFMHETHDGVQDMACDT 587
Query: 501 FATLEEEA--------CTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHH 552
F + ++ E++P++ IL+ + Q + + Y+A+G + +
Sbjct: 588 FIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQ 647
Query: 553 LNQPEYIQKLMPPLIQKWNEL 573
Q I+K M Q W+ +
Sbjct: 648 TVQEHLIEKYMLLPNQVWDSI 668
>gi|4504901 karyopherin alpha 4 [Homo sapiens]
Length = 521
Score = 37.7 bits (86), Expect = 0.048
Identities = 55/227 (24%), Positives = 93/227 (40%), Gaps = 27/227 (11%)
Query: 370 WNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGC-MQG 428
W L + A + + V ++PHL+PLL H E V+ + + +G I G Q
Sbjct: 264 WALSYLTDAGNEQIQMVIDSGIVPHLVPLLS----HQEVKVQTAALRAVGNIVTGTDEQT 319
Query: 429 MVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYA---HWVVSQPPDMHLKPLMTELLKR 485
V + + H L+ K + A W LS V D +L P++ LL +
Sbjct: 320 QVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDK 379
Query: 486 ILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDA--IG 543
G+ Q+ A A + L + V YL I ++ F NLL + DA +
Sbjct: 380 ---GDFGTQKEAAWAISNLTISGRKDQVAYL--IQQNVIPPF-----CNLLTVKDAQVVQ 429
Query: 544 TLADSVGHHLNQPEYIQKLMPPLIQKWNELK-------DEDKDLFPL 583
+ D + + L E + + LI++ L+ E++D++ L
Sbjct: 430 VVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHENEDIYKL 476
Score = 31.6 bits (70), Expect = 3.4
Identities = 31/144 (21%), Positives = 64/144 (44%), Gaps = 7/144 (4%)
Query: 662 RSNIMTLLFQCMQ-DSMPEVRQSSFALLGDLTKACFIHVKPCI-AEFMPILGTNLNPEFI 719
+S I+ +L C++ D P ++ + L ++ + + + +P+ L+
Sbjct: 112 KSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQ 171
Query: 720 SVCNNATWAIGEICMQMGAEMQPYVQM--VLNNLVEIINRPNTPKTLLEN-TAITIGRLG 776
+VC A WA+G I + G + + YV V+ L+ I+ P+ P T L N T + +
Sbjct: 172 NVCEQAVWALGNI-IGDGPQCRDYVISLGVVKPLLSFIS-PSIPITFLRNVTWVMVNLCR 229
Query: 777 YVCPQEVAPMLQQFIRPWCTSLRN 800
+ P +Q+ + C + +
Sbjct: 230 HKDPPPPMETIQEILPALCVLIHH 253
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 37.4 bits (85), Expect = 0.062
Identities = 18/47 (38%), Positives = 25/47 (53%)
Query: 319 DVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAEDDDDDD 365
D E+DE + E +I+P K+ E E + ED EDDDDD+
Sbjct: 156 DEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDE 202
>gi|6912478 karyopherin alpha 6 [Homo sapiens]
Length = 536
Score = 37.0 bits (84), Expect = 0.081
Identities = 39/160 (24%), Positives = 64/160 (40%), Gaps = 13/160 (8%)
Query: 363 DDDALSD--WNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA 420
D D L+D W L S + + V + L+ LL H ++ V + +G
Sbjct: 265 DSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELL----MHNDYKVASPALRAVGN 320
Query: 421 IAEGC-MQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYA---HWVVSQPPDMHLK 476
I G +Q V +P L+ LS K +R ACWT+S + D ++
Sbjct: 321 IVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIF 380
Query: 477 PLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYL 516
P++ E+L++ R ++ A A E + YL
Sbjct: 381 PVLIEILQK---AEFRTRKEAAWAITNATSGGTPEQIRYL 417
>gi|4507397 transcription factor 2 [Homo sapiens]
Length = 557
Score = 36.2 bits (82), Expect = 0.14
Identities = 29/90 (32%), Positives = 38/90 (42%), Gaps = 13/90 (14%)
Query: 276 EFWLTLAEQPICKEVLASHLVQLIPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKP 335
E L + KEVL L +L+P G+K + + G +E D KP
Sbjct: 11 ELLSALLSSGVTKEVLVQALEELLPSPNFGVKLETLPLSPGSG----------AEPDTKP 60
Query: 336 RFHKSRTVTLPHEAERPDGSEDAEDDDDDD 365
FH T+T H R G E +ED DD D
Sbjct: 61 VFH---TLTNGHAKGRLSGDEGSEDGDDYD 87
>gi|54607053 GCN1 general control of amino-acid synthesis 1-like 1
[Homo sapiens]
Length = 2671
Score = 36.2 bits (82), Expect = 0.14
Identities = 31/121 (25%), Positives = 51/121 (42%), Gaps = 8/121 (6%)
Query: 379 ALDVLANVFREELLPH----LLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPYLP 434
A D A L H +LP L L W K + +LGA+A + + LP
Sbjct: 1478 AADDCAKAVMSNLSAHGVKLVLPSLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLP 1537
Query: 435 ELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQ 494
++P L + L+D V+ L R V+ P + + P+ LL + D +++ Q
Sbjct: 1538 NIVPKLTEVLTDSHVKVQKAGQQAL-RQIGSVIRNPEILAIAPV---LLDALTDPSRKTQ 1593
Query: 495 E 495
+
Sbjct: 1594 K 1594
Score = 31.2 bits (69), Expect = 4.5
Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Query: 373 RKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPY 432
R +A L L E++LP ++P+L+ L + ++ + L I + + V Y
Sbjct: 1942 RTIAARTLGDLVRKLGEKILPEIIPILEEGLRSQKSDERQGVCIGLSEIMKSTSRDAVLY 2001
Query: 433 LPE-LIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNK 491
E L+P + L D VR A T + + Q L+ ++ LLK++ D +
Sbjct: 2002 FSESLVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQA----LEDILPFLLKQLDD--E 2055
Query: 492 RVQEAACSAFATLEEEACTELVPYL 516
V E A + ++PYL
Sbjct: 2056 EVSEFALDGLKQVMAIKSRVVLPYL 2080
>gi|21361794 TIP120 protein [Homo sapiens]
Length = 1230
Score = 35.8 bits (81), Expect = 0.18
Identities = 41/207 (19%), Positives = 82/207 (39%), Gaps = 29/207 (14%)
Query: 188 IRSHAIACVNQFIMDRAQALMDNIDTFIEHLFA-LAVDDDPEVRKNVCRALVMLLEVRID 246
+R I + +M + ++ IEHL + L+ +D + + + +
Sbjct: 191 VRKRTIIALGHLVMSCGNIVFVDL---IEHLLSELSKNDSMSTTRTYIQCIAAISRQAGH 247
Query: 247 RLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIPILVNGM 306
R+ ++ II +++ D+ + + + + + C + + H+ +I I +
Sbjct: 248 RIGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRR--CPKEVYPHVSTIINIC---L 302
Query: 307 KYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAEDDDDDDA 366
KY D D +EDE D++ + GS+D DDDD
Sbjct: 303 KYLTYDPNYNYDDEDEDENAMDADGG----------------DDDDQGSDDEYSDDDD-- 344
Query: 367 LSDWNLRKCSAAALDVLANVFREELLP 393
W +R+ +A LD + + R E+LP
Sbjct: 345 -MSWKVRRAAAKCLDAVVST-RHEMLP 369
Score = 30.8 bits (68), Expect = 5.8
Identities = 38/191 (19%), Positives = 71/191 (37%), Gaps = 28/191 (14%)
Query: 127 LLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQFFKHCSP 186
LLP+L L S A++ D + +D N I FL+ +
Sbjct: 966 LLPRLKGYLISGSSYARSSVVTAVKFTISDHPQPIDPLLKN-----CIGDFLKTLEDPDL 1020
Query: 187 KIRSHAIACVNQFIMDRAQALMDNIDTFIEHL------------------FALAVDDDPE 228
+R A+ N ++ + D +DT + HL F VDD +
Sbjct: 1021 NVRRVALVTFNSAAHNKPSLIRDLLDTVLPHLYNETKVRKELIREVEMGPFKHTVDDGLD 1080
Query: 229 VRKNVCRALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICK 288
+RK + LL+ +DRL + + ++ +DH + ++ F + + +C
Sbjct: 1081 IRKAAFECMYTLLDSCLDRL--DIFEFLNHVEDGLKDHYD---IKMLTFLMLVRLSTLCP 1135
Query: 289 EVLASHLVQLI 299
+ L +L+
Sbjct: 1136 SAVLQRLDRLV 1146
>gi|32455246 beta isoform of regulatory subunit A, protein
phosphatase 2 isoform a [Homo sapiens]
Length = 601
Score = 35.4 bits (80), Expect = 0.24
Identities = 63/285 (22%), Positives = 116/285 (40%), Gaps = 56/285 (19%)
Query: 16 LLKDSQSPNTATQRIVQDK----LKQLNQFPD---FNNYLIFVLTRLKSEDEPTRSLS-- 66
LL ++ T + +V+DK L+Q++Q Y + ++ RL S D T S
Sbjct: 101 LLPPLENLATVEETVVRDKAVESLRQISQEHTPVALEAYFVPLVKRLASGDWFTSRTSAC 160
Query: 67 GLI----------LKNNVKAHYQSFPPPVADFIKQECLNNIGDASSL-----IRATIGIL 111
GL +K ++ ++S +++ + +G+ + + +++ I L
Sbjct: 161 GLFSVCYPRASNAVKAEIRQQFRSLCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPL 220
Query: 112 ITTIASKGELQ---MWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSS---------- 158
T++AS + + E + LL+ +D T L++ ED S
Sbjct: 221 FTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETL--VMPTLRQAAEDKSWRVRYMVADR 278
Query: 159 --ELLDSDALNRPLNIMIPKFLQFFKHCSPKIRSHAIACVNQF-----IMDRAQALMDNI 211
EL + LN +IP F K C ++R+ A V + I DR +M+ I
Sbjct: 279 FSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENLPIEDRETIIMNQI 338
Query: 212 DTFIEHLFALAVDDDPEVRKNVCRALVMLL------EVRIDRLIP 250
+I+ L V D + K+ +++M L E I+ L+P
Sbjct: 339 LPYIKEL----VSDTNQHVKSALASVIMGLSTILGKENTIEHLLP 379
>gi|32455244 beta isoform of regulatory subunit A, protein
phosphatase 2 isoform b [Homo sapiens]
Length = 667
Score = 35.4 bits (80), Expect = 0.24
Identities = 63/285 (22%), Positives = 116/285 (40%), Gaps = 56/285 (19%)
Query: 16 LLKDSQSPNTATQRIVQDK----LKQLNQFPD---FNNYLIFVLTRLKSEDEPTRSLS-- 66
LL ++ T + +V+DK L+Q++Q Y + ++ RL S D T S
Sbjct: 101 LLPPLENLATVEETVVRDKAVESLRQISQEHTPVALEAYFVPLVKRLASGDWFTSRTSAC 160
Query: 67 GLI----------LKNNVKAHYQSFPPPVADFIKQECLNNIGDASSL-----IRATIGIL 111
GL +K ++ ++S +++ + +G+ + + +++ I L
Sbjct: 161 GLFSVCYPRASNAVKAEIRQQFRSLCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPL 220
Query: 112 ITTIASKGELQ---MWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSS---------- 158
T++AS + + E + LL+ +D T L++ ED S
Sbjct: 221 FTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETL--VMPTLRQAAEDKSWRVRYMVADR 278
Query: 159 --ELLDSDALNRPLNIMIPKFLQFFKHCSPKIRSHAIACVNQF-----IMDRAQALMDNI 211
EL + LN +IP F K C ++R+ A V + I DR +M+ I
Sbjct: 279 FSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENLPIEDRETIIMNQI 338
Query: 212 DTFIEHLFALAVDDDPEVRKNVCRALVMLL------EVRIDRLIP 250
+I+ L V D + K+ +++M L E I+ L+P
Sbjct: 339 LPYIKEL----VSDTNQHVKSALASVIMGLSTILGKENTIEHLLP 379
>gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription
factor-associated, 170kDa [Homo sapiens]
Length = 1849
Score = 35.4 bits (80), Expect = 0.24
Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 17/117 (14%)
Query: 385 NVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCL 444
N+F E++LP L + + V +E I L + E G+VPY+ L+ ++ +
Sbjct: 1143 NIFLEKVLPWLGAI-------DDSVKQEGAIEALACVMEQLDVGIVPYIVLLVVPVLGRM 1195
Query: 445 SDKKALVRSIACWTLSRYAHWV-----VSQPPDM-----HLKPLMTELLKRILDGNK 491
SD+ VR +A + + + PP+M LK L+++LDG K
Sbjct: 1196 SDQTDSVRFMATQCFATLIRLMPLEAGIPDPPNMSAELIQLKAKERHFLEQLLDGKK 1252
Score = 33.9 bits (76), Expect = 0.69
Identities = 30/132 (22%), Positives = 63/132 (47%), Gaps = 7/132 (5%)
Query: 152 KICEDSSELLDSDALNRPLNIM-IPKFLQFFKHCSPKIRSHAIACVNQFIMDRAQALMDN 210
++ E ++ +DS+ PL + +P ++ S +R A CV +M + A M+
Sbjct: 1087 QVFETAAASMDSEL--HPLLVQHLPHLYMCLQYPSTAVRHMAARCVG--VMSKI-ATMET 1141
Query: 211 IDTFIEHLFA-LAVDDDPEVRKNVCRALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDEN 269
++ F+E + L DD ++ AL ++E ++P++ ++ +L R D ++
Sbjct: 1142 MNIFLEKVLPWLGAIDDSVKQEGAIEALACVMEQLDVGIVPYIVLLVVPVLGRMSDQTDS 1201
Query: 270 VALEACEFWLTL 281
V A + + TL
Sbjct: 1202 VRFMATQCFATL 1213
Score = 30.4 bits (67), Expect = 7.6
Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 3/86 (3%)
Query: 431 PYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGN 490
P L + +PHL CL VR +A + + + ++ L+ ++ L I D
Sbjct: 1102 PLLVQHLPHLYMCLQYPSTAVRHMAARCVGVMSKIATMETMNIFLEKVL-PWLGAIDDSV 1160
Query: 491 KRVQEAACSAFATLEEEACTELVPYL 516
K QE A A A + E+ +VPY+
Sbjct: 1161 K--QEGAIEALACVMEQLDVGIVPYI 1184
>gi|154350213 hypothetical protein LOC79591 [Homo sapiens]
Length = 689
Score = 34.7 bits (78), Expect = 0.40
Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 15/124 (12%)
Query: 202 DRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVMLLEVRIDRLIPHMHSIIQYMLQ 261
D+A+ M N+ +E L +L + E K++C L++ L D + ++I++Y++
Sbjct: 131 DKAELCMKNL---MESLDSLLCAEGSESLKSLCLKLLLCLVTVTDNI--SQNTILEYVMI 185
Query: 262 RTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIPILVNGMKYSEIDIILLKGDVE 321
N EA L + P + V L+ +LVN KY ++ ++K +
Sbjct: 186 -------NSIFEAI---LQILSHPPSRREHGYDAVVLLALLVNYRKYESVNPYIVKLSIV 235
Query: 322 EDEA 325
+DEA
Sbjct: 236 DDEA 239
>gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens]
Length = 1236
Score = 33.9 bits (76), Expect = 0.69
Identities = 40/165 (24%), Positives = 69/165 (41%), Gaps = 24/165 (14%)
Query: 380 LDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMV--------- 430
L LA V L H+ L+ G++F + S + A +QG++
Sbjct: 460 LTELAGVLPGSLAEHMPVLVSGIIFS---LADRSSSSTIRMDALAFLQGLLGTEPAEAFH 516
Query: 431 PYLPELIPHLIQCLSDKKALVRSIACWTLSRY--AHWVVSQPPDMHLKPLMTELLK---- 484
P+LP L+P ++ C++D + + A L A W + +P + +P + E+
Sbjct: 517 PHLPILLPPVMACVADSFYKIAAEALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLA 576
Query: 485 --RILDGNKRVQEAACSAF----ATLEEEACTELVPYLSYILDTL 523
R D ++ V+E A S L + +L P L +LD L
Sbjct: 577 RLRATDLDQEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRL 621
>gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens]
Length = 1119
Score = 33.9 bits (76), Expect = 0.69
Identities = 40/165 (24%), Positives = 69/165 (41%), Gaps = 24/165 (14%)
Query: 380 LDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMV--------- 430
L LA V L H+ L+ G++F + S + A +QG++
Sbjct: 367 LTELAGVLPGSLAEHMPVLVSGIIFS---LADRSSSSTIRMDALAFLQGLLGTEPAEAFH 423
Query: 431 PYLPELIPHLIQCLSDKKALVRSIACWTLSRY--AHWVVSQPPDMHLKPLMTELLK---- 484
P+LP L+P ++ C++D + + A L A W + +P + +P + E+
Sbjct: 424 PHLPILLPPVMACVADSFYKIAAEALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLA 483
Query: 485 --RILDGNKRVQEAACSAF----ATLEEEACTELVPYLSYILDTL 523
R D ++ V+E A S L + +L P L +LD L
Sbjct: 484 RLRATDLDQEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRL 528
>gi|89886480 zinedin isoform 2 [Homo sapiens]
Length = 760
Score = 33.9 bits (76), Expect = 0.69
Identities = 16/50 (32%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
Query: 322 EDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAEDDDDDDALSDWN 371
EDE D + ++ HK + V LP +A P+ ++ E+DD +DA+++++
Sbjct: 272 EDED-SDEDDELDSVQHKKQRVKLPSKALVPEMEDEDEEDDSEDAINEFD 320
>gi|89886477 zinedin isoform 1 [Homo sapiens]
Length = 753
Score = 33.9 bits (76), Expect = 0.69
Identities = 16/50 (32%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
Query: 322 EDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAEDDDDDDALSDWN 371
EDE D + ++ HK + V LP +A P+ ++ E+DD +DA+++++
Sbjct: 272 EDED-SDEDDELDSVQHKKQRVKLPSKALVPEMEDEDEEDDSEDAINEFD 320
>gi|54112117 splicing factor 3b, subunit 1 isoform 1 [Homo sapiens]
Length = 1304
Score = 33.9 bits (76), Expect = 0.69
Identities = 33/116 (28%), Positives = 56/116 (48%), Gaps = 11/116 (9%)
Query: 369 DWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPE-WVVKESGILVLG--AIAEGC 425
D +R +A A V+A+ +P LLP LK + + W + +GI ++ AI GC
Sbjct: 621 DEYVRNTTARAFAVVASALG---IPSLLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGC 677
Query: 426 MQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVS---QPPDMHLKPL 478
++P+L L+ + L D++ VR+I+ ++ A + D LKPL
Sbjct: 678 --AILPHLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAATPYGIESFDSVLKPL 731
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,241,237
Number of Sequences: 37866
Number of extensions: 1512218
Number of successful extensions: 5048
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 4833
Number of HSP's gapped (non-prelim): 203
length of query: 887
length of database: 18,247,518
effective HSP length: 111
effective length of query: 776
effective length of database: 14,044,392
effective search space: 10898448192
effective search space used: 10898448192
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.