Guide to the Human Genome
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Search of human proteins with 48675811

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|48675811 immediate early response 2 [Homo sapiens]
         (223 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|48675811 immediate early response 2 [Homo sapiens]                 444   e-125
gi|142976757 immediate early response 5 [Homo sapiens]                 83   2e-16
gi|148727370 immediate early response 5-like [Homo sapiens]            55   6e-08
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo...    41   7e-04
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo...    41   7e-04
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         40   0.001
gi|223972704 hypothetical protein LOC284418 [Homo sapiens]             39   0.004
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    39   0.005
gi|4502175 apical protein of Xenopus-like [Homo sapiens]               39   0.005
gi|195947369 junction-mediating and regulatory protein [Homo sap...    38   0.006
gi|169162152 PREDICTED: hypothetical protein [Homo sapiens]            38   0.008
gi|169161145 PREDICTED: hypothetical protein [Homo sapiens]            38   0.008
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    37   0.014
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    37   0.014
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    37   0.014
gi|24307909 ral guanine nucleotide dissociation stimulator isofo...    37   0.018
gi|108796058 ral guanine nucleotide dissociation stimulator isof...    37   0.018
gi|156564384 deltex 2 isoform a [Homo sapiens]                         37   0.018
gi|156564382 deltex 2 isoform a [Homo sapiens]                         37   0.018
gi|156564380 deltex 2 isoform a [Homo sapiens]                         37   0.018
gi|189181750 human immunodeficiency virus type I enhancer bindin...    37   0.018
gi|116089331 human immunodeficiency virus type I enhancer bindin...    37   0.018
gi|115511030 hypothetical protein LOC115004 [Homo sapiens]             37   0.018
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    36   0.023
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    36   0.023
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    36   0.023
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ...    36   0.023
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    36   0.030
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ...    36   0.030
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]      35   0.039

>gi|48675811 immediate early response 2 [Homo sapiens]
          Length = 223

 Score =  444 bits (1142), Expect = e-125
 Identities = 223/223 (100%), Positives = 223/223 (100%)

Query: 1   MEVQKEAQRIMTLSVWKMYHSRMQRGGLRLHRSLQLSLVMRSARELYLSAKVEALEPEVS 60
           MEVQKEAQRIMTLSVWKMYHSRMQRGGLRLHRSLQLSLVMRSARELYLSAKVEALEPEVS
Sbjct: 1   MEVQKEAQRIMTLSVWKMYHSRMQRGGLRLHRSLQLSLVMRSARELYLSAKVEALEPEVS 60

Query: 61  LPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSACCAPRPAKVSR 120
           LPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSACCAPRPAKVSR
Sbjct: 61  LPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSACCAPRPAKVSR 120

Query: 121 KRRSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPPAQAEGAFPNLARVLQR 180
           KRRSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPPAQAEGAFPNLARVLQR
Sbjct: 121 KRRSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPPAQAEGAFPNLARVLQR 180

Query: 181 RFSGLLNCSPAAPPTAPPACEAKPACRPADSMLNVLVRAVVAF 223
           RFSGLLNCSPAAPPTAPPACEAKPACRPADSMLNVLVRAVVAF
Sbjct: 181 RFSGLLNCSPAAPPTAPPACEAKPACRPADSMLNVLVRAVVAF 223


>gi|142976757 immediate early response 5 [Homo sapiens]
          Length = 327

 Score = 83.2 bits (204), Expect = 2e-16
 Identities = 65/213 (30%), Positives = 100/213 (46%), Gaps = 17/213 (7%)

Query: 1   MEVQKEAQRIMTLSVWKMYHSRMQRGGLRLHRSLQLSLVMRSARELYLSAKVEALEPEVS 60
           ME + EA RI+++S+ K+Y+SR+QRGG++LH++L +SLV+RSAR++YLS     L   ++
Sbjct: 1   MEFKLEAHRIVSISLGKIYNSRVQRGGIKLHKNLLVSLVLRSARQVYLSDPCPGL--YLA 58

Query: 61  LPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSACCAPR---PAK 117
            PA  P+ P    P E  +       +   P       +  P  E +S   APR      
Sbjct: 59  GPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVP 118

Query: 118 VSRKRRSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPPAQAEGAFPNLARV 177
           V+       +  GG+A    +  +R+E          + A R     A   G FP ++R 
Sbjct: 119 VATVTGVGDVFQGGEADATEAAWSRVE-------GPRQAAAREAEGTAGGWGVFPEVSRA 171

Query: 178 LQRRFSGLLN-----CSPAAPPTAPPACEAKPA 205
            +R     L       +PAA P A   C  +PA
Sbjct: 172 ARRPCGCPLGGEDPPGTPAATPRAACCCAPQPA 204



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 49/191 (25%), Positives = 73/191 (38%), Gaps = 43/191 (22%)

Query: 70  RLHPPREAESTAETATPDGEHPFPE-----------PMDTQEAP----TAEETSACCAPR 114
           R+  PR+A +     T  G   FPE           P+  ++ P         + CCAP+
Sbjct: 143 RVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQ 202

Query: 115 PAK--------VSRKRRSSSLSDGGDAGL-----VPSKKARLEEKEEEEGASSEVADRLQ 161
           PA+        V  ++R ++   GG AG       P KK R   ++   G   + A+ ++
Sbjct: 203 PAEDEPPAPPAVCPRKRCAAGVGGGPAGCPAPGSTPLKKPRRNLEQPPSGGEDDDAEEME 262

Query: 162 PPPAQAEGAFPNLARVLQRRFSGLLNCSPA-------APPTAPPACEAKPAC--RPADSM 212
                  G   NL  +    FSGLL  SP           + P A E    C  +P    
Sbjct: 263 ------TGNVANLISIFGSSFSGLLRKSPGGGREEEEGEESGPEAAEPGQICCDKPVLRD 316

Query: 213 LNVLVRAVVAF 223
           +N    A+VAF
Sbjct: 317 MNPWSTAIVAF 327


>gi|148727370 immediate early response 5-like [Homo sapiens]
          Length = 404

 Score = 54.7 bits (130), Expect = 6e-08
 Identities = 25/55 (45%), Positives = 42/55 (76%)

Query: 1  MEVQKEAQRIMTLSVWKMYHSRMQRGGLRLHRSLQLSLVMRSARELYLSAKVEAL 55
          ME   +AQ ++++S+ K++ SR QRGG++LH++L +S V+R+AR+LYLS +   L
Sbjct: 1  MECALDAQSLISISLRKIHSSRTQRGGIKLHKNLLVSYVLRNARQLYLSERYAEL 55


>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
           sapiens]
          Length = 870

 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 40/152 (26%), Positives = 55/152 (36%), Gaps = 24/152 (15%)

Query: 57  PEVSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQE------APTAEETSAC 110
           P  S  A  PS  +  P  ++  T E  +P    P P P    E      AP+     A 
Sbjct: 690 PPGSEAAPSPSKRKRTPSDKSAHTVEHGSPRTRDPTPRPPGLPEEATALAAPSPPRARAR 749

Query: 111 CAPRPAKVSRKRRSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQP-PPAQAEG 169
            APRP     +RRS +      + L    + +       E A      R +P PP +A+ 
Sbjct: 750 AAPRPLGAHGRRRSPAKRAEAASMLAADVRGKTRSLGRAEVALGAQGPREKPAPPQKAKR 809

Query: 170 AFPNLARVLQRRFSGLLNCSPAAPPTAPPACE 201
           + P                 PA+P  APPA E
Sbjct: 810 SVP-----------------PASPARAPPATE 824


>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
           sapiens]
          Length = 865

 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 40/152 (26%), Positives = 55/152 (36%), Gaps = 24/152 (15%)

Query: 57  PEVSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQE------APTAEETSAC 110
           P  S  A  PS  +  P  ++  T E  +P    P P P    E      AP+     A 
Sbjct: 685 PPGSEAAPSPSKRKRTPSDKSAHTVEHGSPRTRDPTPRPPGLPEEATALAAPSPPRARAR 744

Query: 111 CAPRPAKVSRKRRSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQP-PPAQAEG 169
            APRP     +RRS +      + L    + +       E A      R +P PP +A+ 
Sbjct: 745 AAPRPLGAHGRRRSPAKRAEAASMLAADVRGKTRSLGRAEVALGAQGPREKPAPPQKAKR 804

Query: 170 AFPNLARVLQRRFSGLLNCSPAAPPTAPPACE 201
           + P                 PA+P  APPA E
Sbjct: 805 SVP-----------------PASPARAPPATE 819


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 51/176 (28%), Positives = 70/176 (39%), Gaps = 42/176 (23%)

Query: 59   VSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAE---------ETSA 109
            + LP +  SD  L  P EA+ T+E  T + + P   P   QE  TAE          TS+
Sbjct: 2652 LELPPSAASDEPLQEPLEADRTSEELT-EAKTPTSSPEKPQELVTAEVAAPSTSSSATSS 2710

Query: 110  CCAPRPAKVSRKRRSSSLSDGGDA----GLVPSKKAR----------LEEKE------EE 149
               P PA+  R+R S+ +   G      G  P  K            +EEKE      ++
Sbjct: 2711 PEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQ 2770

Query: 150  EGASSEVADRLQPPPAQAEGAFPNLARVLQRRFSGLLNCSPAAPPTAPPACEAKPA 205
             GA+S +      P      A P    V  R  SG      ++PP   P CEA P+
Sbjct: 2771 RGAASTLV-----PGVSETSASPGSPSV--RSMSG----PESSPPIGGP-CEAAPS 2814


>gi|223972704 hypothetical protein LOC284418 [Homo sapiens]
          Length = 922

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 51/165 (30%), Positives = 64/165 (38%), Gaps = 15/165 (9%)

Query: 48  LSAKVEALEPEVSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEET 107
           LS+    L P    PAA  S P    PR  E     A P G H  P P   Q+AP+   T
Sbjct: 355 LSSAASGLAPYP--PAACLSTPYSSIPRGREK----AGPMGSHQGPGPPPCQKAPSGLVT 408

Query: 108 SACCAPRPAKVSRKRRSSSLSD-GGDAGLVPSKKARL----EEKEEEEGASSEVADRLQP 162
           S C AP     S+K  +   S      GL P +KA        K     A S+ A  + P
Sbjct: 409 S-CKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAV-P 466

Query: 163 PPAQAEGAFPNLARVLQRRFSGLLNCS--PAAPPTAPPACEAKPA 205
            P+Q   A P  +R      +     S  PA P   PP  +  P+
Sbjct: 467 APSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPS 511


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 35/160 (21%), Positives = 64/160 (40%), Gaps = 9/160 (5%)

Query: 57  PEVSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSACCAPRPA 116
           PE S  +  P +  + PP   E +  +  P+    FP   ++  +P  EE+     P  +
Sbjct: 567 PEASRLSPPPEESPMSPP--PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEAS 624

Query: 117 KVSRKRRSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPPAQAE-GAFPNLA 175
           ++S     S +S        P +       E    +   V  RL PPP ++     P  +
Sbjct: 625 RLSPPPEDSPMSPP------PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEES 678

Query: 176 RVLQRRFSGLLNCSPAAPPTAPPACEAKPACRPADSMLNV 215
                  +  L+  P   PT+PP  ++  +  P DS++++
Sbjct: 679 PTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSL 718



 Score = 36.2 bits (82), Expect = 0.023
 Identities = 44/171 (25%), Positives = 64/171 (37%), Gaps = 16/171 (9%)

Query: 57  PEVSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSACCAPRPA 116
           PE S P+     P L PP EA   +         P PE + T   P A   S    P  +
Sbjct: 523 PEESPPSPALETP-LSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSP--PPEES 579

Query: 117 KVSRKRRSSSLSDGGDAGLV--PSKKARLEEKEEEEGAS-SEVADRLQPPPAQAE----- 168
            +S     S +S   +A  +  P +++ L    EE   S    A RL PPP  +      
Sbjct: 580 PMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPP 639

Query: 169 -----GAFPNLARVLQRRFSGLLNCSPAAPPTAPPACEAKPACRPADSMLN 214
                   P ++R+        L+  P   P +PP  E+  +  P  S L+
Sbjct: 640 EESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLS 690



 Score = 35.8 bits (81), Expect = 0.030
 Identities = 53/216 (24%), Positives = 76/216 (35%), Gaps = 34/216 (15%)

Query: 28  LRLHRSLQLSLVMRSARELYLSAKVEAL------EPEVSLPAALPSDPRLHPPREAESTA 81
           L L R L+ S +     E  LS   E+       E  +S P   P  P L  P      A
Sbjct: 483 LHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEA 542

Query: 82  ETATPDGEH----PFPEPMDTQEAPTAEETSACCAPRPAKVSRKRRSSSLSDGGDAGLV- 136
              +P  E     P PE + T   P A   S    P  + +S     S +S   +A  + 
Sbjct: 543 SPLSPPFEESPLSPPPEELPTSPPPEASRLSP--PPEESPMSPPPEESPMSPPPEASRLF 600

Query: 137 -PSKKARLEEKEEEEGASSEV-ADRLQPPPAQAE-------------------GAFPNLA 175
            P +++ L    EE   S    A RL PPP  +                       P ++
Sbjct: 601 PPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS 660

Query: 176 RVLQRRFSGLLNCSPAAPPTAPPACEAKPACRPADS 211
           R+        L+  P   PT+PP   ++ +  P DS
Sbjct: 661 RLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDS 696



 Score = 33.1 bits (74), Expect = 0.20
 Identities = 36/149 (24%), Positives = 57/149 (38%), Gaps = 18/149 (12%)

Query: 56  EPEVSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSACCAPRP 115
           +PE     A+P +P L P  +AE    +  P+  H  P+  +   +P  EE      P  
Sbjct: 773 QPEEPCLCAVPEEPHLSP--QAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEE 830

Query: 116 AKVSRKRRSSSLSDGGDAGLV------PSKKARLEEKEEEEGASSEVAD-RLQPPPAQAE 168
           + +S +     LS   +   +      P    R E+  EE G      +  L PPP +  
Sbjct: 831 SHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGE-- 888

Query: 169 GAFPNLARVLQRRFSGLLNCSPAAPPTAP 197
              P+L+ +L           P  PP +P
Sbjct: 889 ---PSLSPLLGEPALS----EPGEPPLSP 910



 Score = 32.7 bits (73), Expect = 0.26
 Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 7/78 (8%)

Query: 57  PEVSLPAALPSDPRLHPPRE-------AESTAETATPDGEHPFPEPMDTQEAPTAEETSA 109
           PEVS  + LP   RL PP E        E +  +  P+     P P D+  +P  E++ A
Sbjct: 648 PEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPA 707

Query: 110 CCAPRPAKVSRKRRSSSL 127
              P  + +S     S L
Sbjct: 708 SPPPEDSLMSLPLEESPL 725



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 40/175 (22%), Positives = 62/175 (35%), Gaps = 33/175 (18%)

Query: 55  LEPEVSLPA-------ALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEET 107
           LEP++  P          P +  L PP E   T+           P P  ++ +P  EE 
Sbjct: 426 LEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTS-----------PPPEASRLSPPPEEL 474

Query: 108 SACCAPRPAKVSRKRRSSSLSDGGDAGLV--PSKKARLEEKEE------EEGASSEVADR 159
            A   P    +SR    S LS   +   +  P + +     EE      EE   S   + 
Sbjct: 475 PASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET 534

Query: 160 LQPPPAQAEGAFPNLARVLQRRFSGLLNCSPAAPPTAPPACEAKPACRPADSMLN 214
              PP +A    P             L+  P   PT+PP   ++ +  P +S ++
Sbjct: 535 PLSPPPEASPLSPPFE-------ESPLSPPPEELPTSPPPEASRLSPPPEESPMS 582



 Score = 28.5 bits (62), Expect = 4.8
 Identities = 20/51 (39%), Positives = 25/51 (49%), Gaps = 3/51 (5%)

Query: 93   PEP-MDTQEAPTAEETSACCAPRPAKVSRKRRSSSLSDGGDAGLVPSKKAR 142
            P+P M TQ  P A       AP  A VS +    S   GG AGLVP + ++
Sbjct: 3326 PQPLMPTQ--PPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQ 3374


>gi|4502175 apical protein of Xenopus-like [Homo sapiens]
          Length = 1616

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 46/172 (26%), Positives = 70/172 (40%), Gaps = 33/172 (19%)

Query: 56   EPEVSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSAC-CAPR 114
            EP   LP+A+ ++     PR+A++     +P G    P        PT  E S C  AP 
Sbjct: 945  EPREELPSAVRAEEGQSTPRQADAQCREGSP-GSQQHPPSQKAPNPPTFSELSHCRGAPE 1003

Query: 115  PAKVSRKRRSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPP--PAQAEG--A 170
              +  R          G AG +P      + +  EE   +++  R Q P  P  A G  +
Sbjct: 1004 LPREGR----------GRAGTLPR-----DYRYSEESTPADLGPRAQSPGSPLHARGQDS 1048

Query: 171  FPNLARVLQRRFSGLLNCSPAAPPTAPPACEAK----PACRPADSMLNVLVR 218
            +P  + +L +R       +P  PP  PP  E +        PAD+ + VL R
Sbjct: 1049 WPVSSALLSKR------PAPQRPP--PPKREPRRYRATDGAPADAPVGVLGR 1092


>gi|195947369 junction-mediating and regulatory protein [Homo
           sapiens]
          Length = 988

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 9/104 (8%)

Query: 64  ALPSDPRLHPPREAESTAETATPDGEHPFP--EPMDTQEAPTAEETSACCAPRPAKVSRK 121
           +L  DPRL  P    + +   +P    P P  +  +  +A  A   +A  APR A+VS  
Sbjct: 121 SLLGDPRLRSPGSKGAESRLRSPVRAKPIPGQKTSEADDAAGAAAAAARPAPREAQVSSV 180

Query: 122 RRSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPPA 165
           R  S+      +G V S++  + E  +E+ A   ++D  QPPPA
Sbjct: 181 RIVSA------SGTV-SEEIEVLEMVKEDEAPLALSDAEQPPPA 217


>gi|169162152 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 520

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 37/145 (25%), Positives = 53/145 (36%), Gaps = 8/145 (5%)

Query: 62  PAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEA-PTAEETSACCAPRPAKVSR 120
           P  L +   LH PRE       + P    P P+      A P    +      +P + + 
Sbjct: 139 PQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAW 198

Query: 121 KRRSSSL--SDGGDAGLVPSKKARLEEK-----EEEEGASSEVADRLQPPPAQAEGAFPN 173
           ++RSS     +G  A L+PS K     +      EE  A S      + P A+     P 
Sbjct: 199 EQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPP 258

Query: 174 LARVLQRRFSGLLNCSPAAPPTAPP 198
           LAR+L      L      +PP   P
Sbjct: 259 LARLLLASAVSLAASLARSPPPLQP 283


>gi|169161145 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 520

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 37/145 (25%), Positives = 53/145 (36%), Gaps = 8/145 (5%)

Query: 62  PAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEA-PTAEETSACCAPRPAKVSR 120
           P  L +   LH PRE       + P    P P+      A P    +      +P + + 
Sbjct: 139 PQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAW 198

Query: 121 KRRSSSL--SDGGDAGLVPSKKARLEEK-----EEEEGASSEVADRLQPPPAQAEGAFPN 173
           ++RSS     +G  A L+PS K     +      EE  A S      + P A+     P 
Sbjct: 199 EQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPP 258

Query: 174 LARVLQRRFSGLLNCSPAAPPTAPP 198
           LAR+L      L      +PP   P
Sbjct: 259 LARLLLASAVSLAASLARSPPPLQP 283


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 37.0 bits (84), Expect = 0.014
 Identities = 32/127 (25%), Positives = 55/127 (43%), Gaps = 13/127 (10%)

Query: 48   LSAKVEALEPEVSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEET 107
            +S +   +EP VS+P A    P++      + + ET  P  + P PE    +E   AE  
Sbjct: 1182 VSTQACVIEPIVSIPKA-GRKPKI------QESEETVEPKEDMPLPEERKEEEEMQAEAE 1234

Query: 108  SACCAPRPAKVSRKRRSSSLSDGGDAGLVPSKKARLEEKE------EEEGASSEVADRLQ 161
             A         S +  ++S +D  ++    +K+  +EE+E      EE+  S E    L+
Sbjct: 1235 EAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELE 1294

Query: 162  PPPAQAE 168
             P  + E
Sbjct: 1295 EPEPEEE 1301


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 37.0 bits (84), Expect = 0.014
 Identities = 32/127 (25%), Positives = 55/127 (43%), Gaps = 13/127 (10%)

Query: 48   LSAKVEALEPEVSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEET 107
            +S +   +EP VS+P A    P++      + + ET  P  + P PE    +E   AE  
Sbjct: 1182 VSTQACVIEPIVSIPKA-GRKPKI------QESEETVEPKEDMPLPEERKEEEEMQAEAE 1234

Query: 108  SACCAPRPAKVSRKRRSSSLSDGGDAGLVPSKKARLEEKE------EEEGASSEVADRLQ 161
             A         S +  ++S +D  ++    +K+  +EE+E      EE+  S E    L+
Sbjct: 1235 EAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELE 1294

Query: 162  PPPAQAE 168
             P  + E
Sbjct: 1295 EPEPEEE 1301


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 37.0 bits (84), Expect = 0.014
 Identities = 32/127 (25%), Positives = 55/127 (43%), Gaps = 13/127 (10%)

Query: 48   LSAKVEALEPEVSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEET 107
            +S +   +EP VS+P A    P++      + + ET  P  + P PE    +E   AE  
Sbjct: 1182 VSTQACVIEPIVSIPKA-GRKPKI------QESEETVEPKEDMPLPEERKEEEEMQAEAE 1234

Query: 108  SACCAPRPAKVSRKRRSSSLSDGGDAGLVPSKKARLEEKE------EEEGASSEVADRLQ 161
             A         S +  ++S +D  ++    +K+  +EE+E      EE+  S E    L+
Sbjct: 1235 EAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELE 1294

Query: 162  PPPAQAE 168
             P  + E
Sbjct: 1295 EPEPEEE 1301


>gi|24307909 ral guanine nucleotide dissociation stimulator isoform
           1 [Homo sapiens]
          Length = 914

 Score = 36.6 bits (83), Expect = 0.018
 Identities = 36/129 (27%), Positives = 49/129 (37%), Gaps = 11/129 (8%)

Query: 48  LSAKVEALEPEVSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPT---A 104
           L A++E  EP  + P AL   P L P  E E     A      P P P + + APT    
Sbjct: 244 LLAQLEHSEPIEAEPEALSPVPALKPTPELELALTPARAPSPVPAPAP-EPEPAPTPAPG 302

Query: 105 EETSACCAPRPAKVSRKRRSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPP 164
            E     AP P        +  L         P+    LE   E++ A S+  + L+P P
Sbjct: 303 SELEVAPAPAPELQQAPEPAVGLES------APAPALELEPAPEQDPAPSQTLE-LEPAP 355

Query: 165 AQAEGAFPN 173
           A      P+
Sbjct: 356 APVPSLQPS 364


>gi|108796058 ral guanine nucleotide dissociation stimulator isoform
           2 [Homo sapiens]
          Length = 859

 Score = 36.6 bits (83), Expect = 0.018
 Identities = 36/129 (27%), Positives = 49/129 (37%), Gaps = 11/129 (8%)

Query: 48  LSAKVEALEPEVSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPT---A 104
           L A++E  EP  + P AL   P L P  E E     A      P P P + + APT    
Sbjct: 189 LLAQLEHSEPIEAEPEALSPVPALKPTPELELALTPARAPSPVPAPAP-EPEPAPTPAPG 247

Query: 105 EETSACCAPRPAKVSRKRRSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPP 164
            E     AP P        +  L         P+    LE   E++ A S+  + L+P P
Sbjct: 248 SELEVAPAPAPELQQAPEPAVGLES------APAPALELEPAPEQDPAPSQTLE-LEPAP 300

Query: 165 AQAEGAFPN 173
           A      P+
Sbjct: 301 APVPSLQPS 309


>gi|156564384 deltex 2 isoform a [Homo sapiens]
          Length = 622

 Score = 36.6 bits (83), Expect = 0.018
 Identities = 39/136 (28%), Positives = 50/136 (36%), Gaps = 9/136 (6%)

Query: 72  HPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSACCAPRPAKVSRKRRSSSLSDGG 131
           HPP    S   T      +  P     + AP    T+A  A  P+  S+    SSLS  G
Sbjct: 229 HPPHRTASVFGTHQAFAPYNKPSLSGARSAPRLNTTNAWGAAPPSLGSQPLYRSSLSHLG 288

Query: 132 DAGLVPSK------KARLEEKEEEEGASSEVADRLQ-PPPAQAEGAFPNLARVLQRRFSG 184
              L P         A L         S      +Q P P++ + A   +  VL     G
Sbjct: 289 PQHLPPGSSTSGAVSASLPSGPSSSPGSVPATVPMQMPKPSRVQQALAGMTSVLMSAI-G 347

Query: 185 LLNCSPAAP-PTAPPA 199
           L  C   AP PT+PPA
Sbjct: 348 LPVCLSRAPQPTSPPA 363


>gi|156564382 deltex 2 isoform a [Homo sapiens]
          Length = 622

 Score = 36.6 bits (83), Expect = 0.018
 Identities = 39/136 (28%), Positives = 50/136 (36%), Gaps = 9/136 (6%)

Query: 72  HPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSACCAPRPAKVSRKRRSSSLSDGG 131
           HPP    S   T      +  P     + AP    T+A  A  P+  S+    SSLS  G
Sbjct: 229 HPPHRTASVFGTHQAFAPYNKPSLSGARSAPRLNTTNAWGAAPPSLGSQPLYRSSLSHLG 288

Query: 132 DAGLVPSK------KARLEEKEEEEGASSEVADRLQ-PPPAQAEGAFPNLARVLQRRFSG 184
              L P         A L         S      +Q P P++ + A   +  VL     G
Sbjct: 289 PQHLPPGSSTSGAVSASLPSGPSSSPGSVPATVPMQMPKPSRVQQALAGMTSVLMSAI-G 347

Query: 185 LLNCSPAAP-PTAPPA 199
           L  C   AP PT+PPA
Sbjct: 348 LPVCLSRAPQPTSPPA 363


>gi|156564380 deltex 2 isoform a [Homo sapiens]
          Length = 622

 Score = 36.6 bits (83), Expect = 0.018
 Identities = 39/136 (28%), Positives = 50/136 (36%), Gaps = 9/136 (6%)

Query: 72  HPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSACCAPRPAKVSRKRRSSSLSDGG 131
           HPP    S   T      +  P     + AP    T+A  A  P+  S+    SSLS  G
Sbjct: 229 HPPHRTASVFGTHQAFAPYNKPSLSGARSAPRLNTTNAWGAAPPSLGSQPLYRSSLSHLG 288

Query: 132 DAGLVPSK------KARLEEKEEEEGASSEVADRLQ-PPPAQAEGAFPNLARVLQRRFSG 184
              L P         A L         S      +Q P P++ + A   +  VL     G
Sbjct: 289 PQHLPPGSSTSGAVSASLPSGPSSSPGSVPATVPMQMPKPSRVQQALAGMTSVLMSAI-G 347

Query: 185 LLNCSPAAP-PTAPPA 199
           L  C   AP PT+PPA
Sbjct: 348 LPVCLSRAPQPTSPPA 363


>gi|189181750 human immunodeficiency virus type I enhancer binding
            protein 3 b [Homo sapiens]
          Length = 2405

 Score = 36.6 bits (83), Expect = 0.018
 Identities = 45/151 (29%), Positives = 57/151 (37%), Gaps = 22/151 (14%)

Query: 76   EAESTAETATPDGEHPFPEPMDTQEA---------PTAEETSACCAPRPAKVSRKRR--- 123
            E ES  E + P  E P P P     A         P     S   A R + VS   R   
Sbjct: 1867 EEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTA 1926

Query: 124  -SSSLSDGGDAGLVPSKKARLEEKEEEEGAS---SEVADRLQPPPAQAEGAFPNLAR--V 177
             S S+S     GL     A L   E++ G++     V+ R    P++  G+ P LAR   
Sbjct: 1927 SSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHS 1986

Query: 178  LQRRFSGLLNCSPAAPPTA----PPACEAKP 204
            L +  S    CSPA  P A    PP     P
Sbjct: 1987 LTKNDSSPQRCSPAREPQASAPSPPGLHVDP 2017



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 6/77 (7%)

Query: 92  FPEPMDTQEAPTAEETSACCAPRPAKVSRKRRSSSLSDGGDAGLVPSKKARLEEKEEEEG 151
           F EP + +   + EETSA     PA++S + +   LS G     + S  +     E    
Sbjct: 273 FEEPTEGESTDSEEETSATSG-HPAELSPRPKQPLLSSG-----LYSSGSHSSSHERCSL 326

Query: 152 ASSEVADRLQPPPAQAE 168
           + S  A  L+ PP   E
Sbjct: 327 SQSSTAQSLEDPPPFVE 343


>gi|116089331 human immunodeficiency virus type I enhancer binding
            protein 3 [Homo sapiens]
          Length = 2406

 Score = 36.6 bits (83), Expect = 0.018
 Identities = 45/151 (29%), Positives = 57/151 (37%), Gaps = 22/151 (14%)

Query: 76   EAESTAETATPDGEHPFPEPMDTQEA---------PTAEETSACCAPRPAKVSRKRR--- 123
            E ES  E + P  E P P P     A         P     S   A R + VS   R   
Sbjct: 1867 EEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTA 1926

Query: 124  -SSSLSDGGDAGLVPSKKARLEEKEEEEGAS---SEVADRLQPPPAQAEGAFPNLAR--V 177
             S S+S     GL     A L   E++ G++     V+ R    P++  G+ P LAR   
Sbjct: 1927 SSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHS 1986

Query: 178  LQRRFSGLLNCSPAAPPTA----PPACEAKP 204
            L +  S    CSPA  P A    PP     P
Sbjct: 1987 LTKNDSSPQRCSPAREPQASAPSPPGLHVDP 2017



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 6/77 (7%)

Query: 92  FPEPMDTQEAPTAEETSACCAPRPAKVSRKRRSSSLSDGGDAGLVPSKKARLEEKEEEEG 151
           F EP + +   + EETSA     PA++S + +   LS G     + S  +     E    
Sbjct: 273 FEEPTEGESTDSEEETSATSG-HPAELSPRPKQPLLSSG-----LYSSGSHSSSHERCSL 326

Query: 152 ASSEVADRLQPPPAQAE 168
           + S  A  L+ PP   E
Sbjct: 327 SQSSTAQSLEDPPPFVE 343


>gi|115511030 hypothetical protein LOC115004 [Homo sapiens]
          Length = 522

 Score = 36.6 bits (83), Expect = 0.018
 Identities = 34/137 (24%), Positives = 54/137 (39%), Gaps = 15/137 (10%)

Query: 50  AKVEALEPEVSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSA 109
           A ++  E   +  AALP   +  P R++ S  + + PD          TQE P    T A
Sbjct: 30  APMDPTESPAAPEAALPKAGKFGPARKSGSRQKKSAPD----------TQERPPVRATGA 79

Query: 110 CCAPRPAKVSRKRRSSSLSDGGDAGLVP--SKKARLEEKEEEEGASSEVADRLQPPPAQA 167
                P +    + S + S  G  GL P  +++  L          +  + + +PPP   
Sbjct: 80  RAKKAPQRAQDTQPSDATSAPGAEGLEPPAAREPALSRAGSCRQRGARCSTKPRPPPGPW 139

Query: 168 EGAFPNL---ARVLQRR 181
           +   P L   A +L RR
Sbjct: 140 DVPSPGLPVSAPILVRR 156


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
           [Homo sapiens]
          Length = 1451

 Score = 36.2 bits (82), Expect = 0.023
 Identities = 41/170 (24%), Positives = 68/170 (40%), Gaps = 12/170 (7%)

Query: 51  KVEALEPEVSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSAC 110
           KV  + P+V   A  P+     P  E+ES+ E +  + E P       + +    +  A 
Sbjct: 244 KVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAA 303

Query: 111 CAPRPAKVSRKRRSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPP------ 164
            AP         + ++ +  G AG V S+    + +E+ E +S E +D  +  P      
Sbjct: 304 SAPAKGTPG---KGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360

Query: 165 -AQAEGAFPNL-ARVLQRRFSGLLNCSPAAP-PTAPPACEAKPACRPADS 211
            A+A G    + A     + S     +PA P  T P   +A+   R  DS
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDS 410



 Score = 35.8 bits (81), Expect = 0.030
 Identities = 40/153 (26%), Positives = 67/153 (43%), Gaps = 7/153 (4%)

Query: 64  ALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSAC-CAPRPAKVSRKR 122
           A+ S  +   P E   ++   + D E   P      +A  + +TS    A  PAK S  R
Sbjct: 325 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKES-PR 383

Query: 123 RSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPPAQAE--GAFPNL-ARVLQ 179
           + ++ +  G  G   +K    + +E+ + +SSE +D  +  PAQA+  G  P + A    
Sbjct: 384 KGAAPAPPGKTGPAVAKAQAGKREEDSQ-SSSEESDSEEEAPAQAKPSGKAPQVRAASAP 442

Query: 180 RRFSGLLNCSPAAP-PTAPPACEAKPACRPADS 211
            + S     +PA P  T P A + +   +  DS
Sbjct: 443 AKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDS 475



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 29/111 (26%), Positives = 42/111 (37%), Gaps = 26/111 (23%)

Query: 54   ALEPEVSLP--AALPSDPRLHPPREAE--------STAETATPDGEHP------------ 91
            AL P    P   A P+ P    P  A+        S++E +  DGE P            
Sbjct: 899  ALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPP 958

Query: 92   --FPEPMDTQEAPTAE--ETSACCAPRPAKVSRKRRSSSLSDGGDAGLVPS 138
              F +P  +   P A   +  A   PR A+ S     SS S+  D  ++P+
Sbjct: 959  LIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPA 1009


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
           [Homo sapiens]
          Length = 1488

 Score = 36.2 bits (82), Expect = 0.023
 Identities = 41/170 (24%), Positives = 68/170 (40%), Gaps = 12/170 (7%)

Query: 51  KVEALEPEVSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSAC 110
           KV  + P+V   A  P+     P  E+ES+ E +  + E P       + +    +  A 
Sbjct: 244 KVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAA 303

Query: 111 CAPRPAKVSRKRRSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPP------ 164
            AP         + ++ +  G AG V S+    + +E+ E +S E +D  +  P      
Sbjct: 304 SAPAKGTPG---KGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360

Query: 165 -AQAEGAFPNL-ARVLQRRFSGLLNCSPAAP-PTAPPACEAKPACRPADS 211
            A+A G    + A     + S     +PA P  T P   +A+   R  DS
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDS 410



 Score = 35.8 bits (81), Expect = 0.030
 Identities = 40/153 (26%), Positives = 67/153 (43%), Gaps = 7/153 (4%)

Query: 64  ALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSAC-CAPRPAKVSRKR 122
           A+ S  +   P E   ++   + D E   P      +A  + +TS    A  PAK S  R
Sbjct: 325 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKES-PR 383

Query: 123 RSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPPAQAE--GAFPNL-ARVLQ 179
           + ++ +  G  G   +K    + +E+ + +SSE +D  +  PAQA+  G  P + A    
Sbjct: 384 KGAAPAPPGKTGPAVAKAQAGKREEDSQ-SSSEESDSEEEAPAQAKPSGKAPQVRAASAP 442

Query: 180 RRFSGLLNCSPAAP-PTAPPACEAKPACRPADS 211
            + S     +PA P  T P A + +   +  DS
Sbjct: 443 AKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDS 475



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 29/111 (26%), Positives = 42/111 (37%), Gaps = 26/111 (23%)

Query: 54   ALEPEVSLP--AALPSDPRLHPPREAE--------STAETATPDGEHP------------ 91
            AL P    P   A P+ P    P  A+        S++E +  DGE P            
Sbjct: 899  ALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPP 958

Query: 92   --FPEPMDTQEAPTAE--ETSACCAPRPAKVSRKRRSSSLSDGGDAGLVPS 138
              F +P  +   P A   +  A   PR A+ S     SS S+  D  ++P+
Sbjct: 959  LIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPA 1009


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
           [Homo sapiens]
          Length = 1450

 Score = 36.2 bits (82), Expect = 0.023
 Identities = 41/170 (24%), Positives = 68/170 (40%), Gaps = 12/170 (7%)

Query: 51  KVEALEPEVSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSAC 110
           KV  + P+V   A  P+     P  E+ES+ E +  + E P       + +    +  A 
Sbjct: 244 KVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAA 303

Query: 111 CAPRPAKVSRKRRSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPP------ 164
            AP         + ++ +  G AG V S+    + +E+ E +S E +D  +  P      
Sbjct: 304 SAPAKGTPG---KGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360

Query: 165 -AQAEGAFPNL-ARVLQRRFSGLLNCSPAAP-PTAPPACEAKPACRPADS 211
            A+A G    + A     + S     +PA P  T P   +A+   R  DS
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDS 410



 Score = 35.8 bits (81), Expect = 0.030
 Identities = 40/153 (26%), Positives = 67/153 (43%), Gaps = 7/153 (4%)

Query: 64  ALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSAC-CAPRPAKVSRKR 122
           A+ S  +   P E   ++   + D E   P      +A  + +TS    A  PAK S  R
Sbjct: 325 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKES-PR 383

Query: 123 RSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPPAQAE--GAFPNL-ARVLQ 179
           + ++ +  G  G   +K    + +E+ + +SSE +D  +  PAQA+  G  P + A    
Sbjct: 384 KGAAPAPPGKTGPAVAKAQAGKREEDSQ-SSSEESDSEEEAPAQAKPSGKAPQVRAASAP 442

Query: 180 RRFSGLLNCSPAAP-PTAPPACEAKPACRPADS 211
            + S     +PA P  T P A + +   +  DS
Sbjct: 443 AKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDS 475



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 29/111 (26%), Positives = 42/111 (37%), Gaps = 26/111 (23%)

Query: 54   ALEPEVSLP--AALPSDPRLHPPREAE--------STAETATPDGEHP------------ 91
            AL P    P   A P+ P    P  A+        S++E +  DGE P            
Sbjct: 899  ALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPP 958

Query: 92   --FPEPMDTQEAPTAE--ETSACCAPRPAKVSRKRRSSSLSDGGDAGLVPS 138
              F +P  +   P A   +  A   PR A+ S     SS S+  D  ++P+
Sbjct: 959  LIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPA 1009


>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
           [Homo sapiens]
          Length = 958

 Score = 36.2 bits (82), Expect = 0.023
 Identities = 41/170 (24%), Positives = 68/170 (40%), Gaps = 12/170 (7%)

Query: 51  KVEALEPEVSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSAC 110
           KV  + P+V   A  P+     P  E+ES+ E +  + E P       + +    +  A 
Sbjct: 244 KVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAA 303

Query: 111 CAPRPAKVSRKRRSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPP------ 164
            AP         + ++ +  G AG V S+    + +E+ E +S E +D  +  P      
Sbjct: 304 SAPAKGTPG---KGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360

Query: 165 -AQAEGAFPNL-ARVLQRRFSGLLNCSPAAP-PTAPPACEAKPACRPADS 211
            A+A G    + A     + S     +PA P  T P   +A+   R  DS
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDS 410



 Score = 35.8 bits (81), Expect = 0.030
 Identities = 40/153 (26%), Positives = 67/153 (43%), Gaps = 7/153 (4%)

Query: 64  ALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSAC-CAPRPAKVSRKR 122
           A+ S  +   P E   ++   + D E   P      +A  + +TS    A  PAK S  R
Sbjct: 325 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKES-PR 383

Query: 123 RSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPPAQAE--GAFPNL-ARVLQ 179
           + ++ +  G  G   +K    + +E+ + +SSE +D  +  PAQA+  G  P + A    
Sbjct: 384 KGAAPAPPGKTGPAVAKAQAGKREEDSQ-SSSEESDSEEEAPAQAKPSGKAPQVRAASAP 442

Query: 180 RRFSGLLNCSPAAP-PTAPPACEAKPACRPADS 211
            + S     +PA P  T P A + +   +  DS
Sbjct: 443 AKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDS 475


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
           [Homo sapiens]
          Length = 1412

 Score = 35.8 bits (81), Expect = 0.030
 Identities = 40/153 (26%), Positives = 67/153 (43%), Gaps = 7/153 (4%)

Query: 64  ALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSAC-CAPRPAKVSRKR 122
           A+ S  +   P E   ++   + D E   P      +A  + +TS    A  PAK S  R
Sbjct: 248 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKES-PR 306

Query: 123 RSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPPAQAE--GAFPNL-ARVLQ 179
           + ++ +  G  G   +K    + +E+ + +SSE +D  +  PAQA+  G  P + A    
Sbjct: 307 KGAAPAPPGKTGPAVAKAQAGKREEDSQ-SSSEESDSEEEAPAQAKPSGKAPQVRAASAP 365

Query: 180 RRFSGLLNCSPAAP-PTAPPACEAKPACRPADS 211
            + S     +PA P  T P A + +   +  DS
Sbjct: 366 AKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDS 398



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 29/111 (26%), Positives = 42/111 (37%), Gaps = 26/111 (23%)

Query: 54  ALEPEVSLP--AALPSDPRLHPPREAE--------STAETATPDGEHP------------ 91
           AL P    P   A P+ P    P  A+        S++E +  DGE P            
Sbjct: 822 ALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPP 881

Query: 92  --FPEPMDTQEAPTAE--ETSACCAPRPAKVSRKRRSSSLSDGGDAGLVPS 138
             F +P  +   P A   +  A   PR A+ S     SS S+  D  ++P+
Sbjct: 882 LIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPA 932


>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
           [Homo sapiens]
          Length = 1411

 Score = 35.8 bits (81), Expect = 0.030
 Identities = 40/153 (26%), Positives = 67/153 (43%), Gaps = 7/153 (4%)

Query: 64  ALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSAC-CAPRPAKVSRKR 122
           A+ S  +   P E   ++   + D E   P      +A  + +TS    A  PAK S  R
Sbjct: 248 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKES-PR 306

Query: 123 RSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPPAQAE--GAFPNL-ARVLQ 179
           + ++ +  G  G   +K    + +E+ + +SSE +D  +  PAQA+  G  P + A    
Sbjct: 307 KGAAPAPPGKTGPAVAKAQAGKREEDSQ-SSSEESDSEEEAPAQAKPSGKAPQVRAASAP 365

Query: 180 RRFSGLLNCSPAAP-PTAPPACEAKPACRPADS 211
            + S     +PA P  T P A + +   +  DS
Sbjct: 366 AKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDS 398



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 29/111 (26%), Positives = 42/111 (37%), Gaps = 26/111 (23%)

Query: 54  ALEPEVSLP--AALPSDPRLHPPREAE--------STAETATPDGEHP------------ 91
           AL P    P   A P+ P    P  A+        S++E +  DGE P            
Sbjct: 822 ALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPP 881

Query: 92  --FPEPMDTQEAPTAE--ETSACCAPRPAKVSRKRRSSSLSDGGDAGLVPS 138
             F +P  +   P A   +  A   PR A+ S     SS S+  D  ++P+
Sbjct: 882 LIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPA 932


>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
          Length = 1312

 Score = 35.4 bits (80), Expect = 0.039
 Identities = 47/186 (25%), Positives = 66/186 (35%), Gaps = 29/186 (15%)

Query: 56  EPEVSLPAALPS----------DPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAE 105
           +P +  P A PS          DP    P  + +      PD E P   P  T    TA 
Sbjct: 600 DPAIPAPTATPSARGAVIRQNSDPTSEGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATAL 659

Query: 106 ETSACCAPRPAKVSRKR-RSSS-----LSDGGDAGLVPSKKARLEEKEEEEGASSEVADR 159
            TS     RPA+  R R RS+S     L    + G         +       +S+    R
Sbjct: 660 NTSGAGGSRPAQAVRARPRSNSAWQIYLQRRAERGTPKPPGPPAQPPGPPNASSNPDLRR 719

Query: 160 LQPPPAQAEGAFP------NLARVLQRRFSGLLNCSPAAPPTAPPACEAKP------ACR 207
             P   +++   P        A  L+R   G ++  P + P   P  +AKP        R
Sbjct: 720 SDPGWERSDSVLPASHGHLPQAGSLERNRVG-VSSKPDSSPVLSPGNKAKPDDHRSRPGR 778

Query: 208 PADSML 213
           PAD +L
Sbjct: 779 PADFVL 784


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.127    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,261,704
Number of Sequences: 37866
Number of extensions: 562490
Number of successful extensions: 4227
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 376
Number of HSP's that attempted gapping in prelim test: 3729
Number of HSP's gapped (non-prelim): 831
length of query: 223
length of database: 18,247,518
effective HSP length: 98
effective length of query: 125
effective length of database: 14,536,650
effective search space: 1817081250
effective search space used: 1817081250
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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