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Search of human proteins with 13376212
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13376212 ubiquitin-activating enzyme 5 isoform 1 [Homo
sapiens]
(404 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13376212 ubiquitin-activating enzyme 5 isoform 1 [Homo sapiens] 802 0.0
gi|38327032 ubiquitin-activating enzyme 5 isoform 2 [Homo sapiens] 697 0.0
gi|7657339 molybdenum cofactor synthesis 3 [Homo sapiens] 67 3e-11
gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens] 62 1e-09
gi|23510338 ubiquitin-activating enzyme E1 [Homo sapiens] 52 1e-06
gi|23510340 ubiquitin-activating enzyme E1 [Homo sapiens] 52 1e-06
gi|150417996 ubiquitin-activating enzyme E1-like 2 [Homo sapiens] 52 1e-06
gi|38045948 ubiquitin-like modifier activating enzyme 7 [Homo sa... 50 3e-06
gi|38045942 ubiquitin-activating enzyme 3 isoform 1 [Homo sapiens] 48 2e-05
gi|38045944 ubiquitin-activating enzyme 3 isoform 2 [Homo sapiens] 47 4e-05
gi|33946313 ninein isoform 4 [Homo sapiens] 37 0.032
gi|33946321 ninein isoform 5 [Homo sapiens] 37 0.032
gi|148536871 ninein isoform 1 [Homo sapiens] 37 0.032
gi|148536869 ninein isoform 2 [Homo sapiens] 37 0.032
gi|225543288 SUMO1 activating enzyme subunit 1 isoform c [Homo s... 35 0.16
gi|225543285 SUMO1 activating enzyme subunit 1 isoform b [Homo s... 35 0.16
gi|4885585 SUMO1 activating enzyme subunit 1 isoform a [Homo sap... 35 0.16
gi|7705473 SUMO1 activating enzyme subunit 1 isoform a [Homo sap... 35 0.16
gi|87298939 hypothetical protein LOC131831 [Homo sapiens] 33 0.46
gi|221219020 NYD-SP11 protein [Homo sapiens] 33 0.60
gi|150170670 piccolo isoform 2 [Homo sapiens] 32 0.78
gi|150378539 piccolo isoform 1 [Homo sapiens] 32 0.78
gi|110349719 titin isoform N2-A [Homo sapiens] 32 1.0
gi|4826724 zygin 1 isoform 1 [Homo sapiens] 31 1.7
gi|16418451 hypothetical protein LOC116328 [Homo sapiens] 31 1.7
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 31 2.3
gi|66363686 NEDD8 activating enzyme E1 subunit 1 isoform b [Homo... 31 2.3
gi|4502169 NEDD8 activating enzyme E1 subunit 1 isoform a [Homo ... 31 2.3
gi|53831997 suppressor of cytokine signaling 7 [Homo sapiens] 31 2.3
gi|94536811 NEDD4-like ubiquitin-protein ligase 1 [Homo sapiens] 30 3.0
>gi|13376212 ubiquitin-activating enzyme 5 isoform 1 [Homo sapiens]
Length = 404
Score = 802 bits (2072), Expect = 0.0
Identities = 404/404 (100%), Positives = 404/404 (100%)
Query: 1 MAESVERLQQRVQELERELAQERSLQVPRSGDGGGGRVRIEKMSSEVVDSNPYSRLMALK 60
MAESVERLQQRVQELERELAQERSLQVPRSGDGGGGRVRIEKMSSEVVDSNPYSRLMALK
Sbjct: 1 MAESVERLQQRVQELERELAQERSLQVPRSGDGGGGRVRIEKMSSEVVDSNPYSRLMALK 60
Query: 61 RMGIVSDYEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLFFQP 120
RMGIVSDYEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLFFQP
Sbjct: 61 RMGIVSDYEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLFFQP 120
Query: 121 HQAGLSKVQAAEHTLRNINPDVLFEVHNYNITTVENFQHFMDRISNGGLEEGKPVDLVLS 180
HQAGLSKVQAAEHTLRNINPDVLFEVHNYNITTVENFQHFMDRISNGGLEEGKPVDLVLS
Sbjct: 121 HQAGLSKVQAAEHTLRNINPDVLFEVHNYNITTVENFQHFMDRISNGGLEEGKPVDLVLS 180
Query: 181 CVDNFEARMTINTACNELGQTWMESGVSENAVSGHIQLIIPGESACFACAPPLVVAANID 240
CVDNFEARMTINTACNELGQTWMESGVSENAVSGHIQLIIPGESACFACAPPLVVAANID
Sbjct: 181 CVDNFEARMTINTACNELGQTWMESGVSENAVSGHIQLIIPGESACFACAPPLVVAANID 240
Query: 241 EKTLKREGVCAASLPTTMGVVAGILVQNVLKFLLNFGTVSFYLGYNAMQDFFPTMSMKPN 300
EKTLKREGVCAASLPTTMGVVAGILVQNVLKFLLNFGTVSFYLGYNAMQDFFPTMSMKPN
Sbjct: 241 EKTLKREGVCAASLPTTMGVVAGILVQNVLKFLLNFGTVSFYLGYNAMQDFFPTMSMKPN 300
Query: 301 PQCDDRNCRKQQEEYKKKVAALPKQEVIQEEEEIIHEDNEWGIELVSEVSEEELKNFSGP 360
PQCDDRNCRKQQEEYKKKVAALPKQEVIQEEEEIIHEDNEWGIELVSEVSEEELKNFSGP
Sbjct: 301 PQCDDRNCRKQQEEYKKKVAALPKQEVIQEEEEIIHEDNEWGIELVSEVSEEELKNFSGP 360
Query: 361 VPDLPEGITVAYTIPKKQEDSVTELTVEDSGESLEDLMAKMKNM 404
VPDLPEGITVAYTIPKKQEDSVTELTVEDSGESLEDLMAKMKNM
Sbjct: 361 VPDLPEGITVAYTIPKKQEDSVTELTVEDSGESLEDLMAKMKNM 404
>gi|38327032 ubiquitin-activating enzyme 5 isoform 2 [Homo sapiens]
Length = 348
Score = 697 bits (1799), Expect = 0.0
Identities = 348/348 (100%), Positives = 348/348 (100%)
Query: 57 MALKRMGIVSDYEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRL 116
MALKRMGIVSDYEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRL
Sbjct: 1 MALKRMGIVSDYEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRL 60
Query: 117 FFQPHQAGLSKVQAAEHTLRNINPDVLFEVHNYNITTVENFQHFMDRISNGGLEEGKPVD 176
FFQPHQAGLSKVQAAEHTLRNINPDVLFEVHNYNITTVENFQHFMDRISNGGLEEGKPVD
Sbjct: 61 FFQPHQAGLSKVQAAEHTLRNINPDVLFEVHNYNITTVENFQHFMDRISNGGLEEGKPVD 120
Query: 177 LVLSCVDNFEARMTINTACNELGQTWMESGVSENAVSGHIQLIIPGESACFACAPPLVVA 236
LVLSCVDNFEARMTINTACNELGQTWMESGVSENAVSGHIQLIIPGESACFACAPPLVVA
Sbjct: 121 LVLSCVDNFEARMTINTACNELGQTWMESGVSENAVSGHIQLIIPGESACFACAPPLVVA 180
Query: 237 ANIDEKTLKREGVCAASLPTTMGVVAGILVQNVLKFLLNFGTVSFYLGYNAMQDFFPTMS 296
ANIDEKTLKREGVCAASLPTTMGVVAGILVQNVLKFLLNFGTVSFYLGYNAMQDFFPTMS
Sbjct: 181 ANIDEKTLKREGVCAASLPTTMGVVAGILVQNVLKFLLNFGTVSFYLGYNAMQDFFPTMS 240
Query: 297 MKPNPQCDDRNCRKQQEEYKKKVAALPKQEVIQEEEEIIHEDNEWGIELVSEVSEEELKN 356
MKPNPQCDDRNCRKQQEEYKKKVAALPKQEVIQEEEEIIHEDNEWGIELVSEVSEEELKN
Sbjct: 241 MKPNPQCDDRNCRKQQEEYKKKVAALPKQEVIQEEEEIIHEDNEWGIELVSEVSEEELKN 300
Query: 357 FSGPVPDLPEGITVAYTIPKKQEDSVTELTVEDSGESLEDLMAKMKNM 404
FSGPVPDLPEGITVAYTIPKKQEDSVTELTVEDSGESLEDLMAKMKNM
Sbjct: 301 FSGPVPDLPEGITVAYTIPKKQEDSVTELTVEDSGESLEDLMAKMKNM 348
>gi|7657339 molybdenum cofactor synthesis 3 [Homo sapiens]
Length = 460
Score = 67.0 bits (162), Expect = 3e-11
Identities = 60/214 (28%), Positives = 90/214 (42%), Gaps = 25/214 (11%)
Query: 53 YSRLMALKRMGIVSDYEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELAN 112
YSR + L +G+ ++ T V IVG GG+G A+ L G+G+L L DYD VE++N
Sbjct: 63 YSRQLVLPELGVHGQL-RLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGLVDYDVVEMSN 121
Query: 113 MNRLFFQPHQ-AGLSKVQAAEHTLRNINPDVLFEVHNYNITTVENFQHFMDRISNGGLEE 171
+ R AG +K +A +LR +N V + +T L+
Sbjct: 122 LARQVLHGEALAGQAKAFSAAASLRRLNSAVECVPYTQALTPAT------------ALDL 169
Query: 172 GKPVDLVLSCVDNFEARMTINTACNELGQTWMESGVSENAVSGHIQLIIPGESACFACAP 231
+ D+V C DN R +N AC G+ + + S G I + C+ C
Sbjct: 170 VRRYDVVADCSDNVPTRYLVNDACVLAGRPLVSA--SALRFEGQITVYHYDGGPCYRCIF 227
Query: 232 PLVVAANIDEKTLKREGVCAASLPTTMGVVAGIL 265
P A E V + +GVV G+L
Sbjct: 228 PQPPPA---------ETVTNCADGGVLGVVTGVL 252
>gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens]
Length = 640
Score = 61.6 bits (148), Expect = 1e-09
Identities = 45/161 (27%), Positives = 71/161 (44%), Gaps = 22/161 (13%)
Query: 76 VAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLF-FQPHQAGLSKVQAAEHT 134
V +VG GG+G + L G + L D D ++++N+NR F FQ G SK Q A+ +
Sbjct: 20 VLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKES 79
Query: 135 LRNINPDVLFEVHNYNIT----TVENFQHFMDRISNGGLEEGKPVDLVLSCVDNFEARMT 190
+ P ++ +I VE F+ F+ LV++ +DN AR
Sbjct: 80 VLQFYPKANIVAYHDSIMNPDYNVEFFRQFI---------------LVMNALDNRAARNH 124
Query: 191 INTACNELGQTWMESGVSENAVSGHIQLIIPGESACFACAP 231
+N C +ESG + G + I G + C+ C P
Sbjct: 125 VNRMCLAADVPLIESGTA--GYLGQVTTIKKGVTECYECHP 163
>gi|23510338 ubiquitin-activating enzyme E1 [Homo sapiens]
Length = 1058
Score = 52.0 bits (123), Expect = 1e-06
Identities = 40/159 (25%), Positives = 70/159 (44%), Gaps = 16/159 (10%)
Query: 69 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIG-----KLLLFDYDKVELANMNRLF-FQPHQ 122
EK+ +VG G +G + G+G ++++ D D +E +N+NR F F+P
Sbjct: 464 EKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRPWD 523
Query: 123 AGLSKVQAAEHTLRNINPDVLFEVHNYNITTVENFQHFMDRISNGGLEEGKPVDLVLSCV 182
K A +R +NP + H + + D N +D V + +
Sbjct: 524 VTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQN--------LDGVANAL 575
Query: 183 DNFEARMTINTACNELGQTWMESGVSENAVSGHIQLIIP 221
DN +ARM ++ C + +ESG G++Q++IP
Sbjct: 576 DNVDARMYMDRRCVYYRKPLLESGTL--GTKGNVQVVIP 612
>gi|23510340 ubiquitin-activating enzyme E1 [Homo sapiens]
Length = 1058
Score = 52.0 bits (123), Expect = 1e-06
Identities = 40/159 (25%), Positives = 70/159 (44%), Gaps = 16/159 (10%)
Query: 69 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIG-----KLLLFDYDKVELANMNRLF-FQPHQ 122
EK+ +VG G +G + G+G ++++ D D +E +N+NR F F+P
Sbjct: 464 EKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRPWD 523
Query: 123 AGLSKVQAAEHTLRNINPDVLFEVHNYNITTVENFQHFMDRISNGGLEEGKPVDLVLSCV 182
K A +R +NP + H + + D N +D V + +
Sbjct: 524 VTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQN--------LDGVANAL 575
Query: 183 DNFEARMTINTACNELGQTWMESGVSENAVSGHIQLIIP 221
DN +ARM ++ C + +ESG G++Q++IP
Sbjct: 576 DNVDARMYMDRRCVYYRKPLLESGTL--GTKGNVQVVIP 612
>gi|150417996 ubiquitin-activating enzyme E1-like 2 [Homo sapiens]
Length = 1052
Score = 51.6 bits (122), Expect = 1e-06
Identities = 37/164 (22%), Positives = 72/164 (43%), Gaps = 25/164 (15%)
Query: 69 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGK------LLLFDYDKVELANMNRLF-FQPH 121
+K++ + +VG G +G + G+G + + D D +E +N+NR F F+PH
Sbjct: 456 QKLQNLNIFLVGCGAIGCEMLKNFALLGVGTSKEKGMITVTDPDLIEKSNLNRQFLFRPH 515
Query: 122 QAGLSKVQAAEHTLRNINPDVLFEVHNYNIT----TVENFQHFMDRISNGGLEEGKPVDL 177
K A IN + + H + T+ N + + + D+
Sbjct: 516 HIQKPKSYTAADATLKINSQIKIDAHLNKVCPTTETIYNDEFYTKQ------------DV 563
Query: 178 VLSCVDNFEARMTINTACNELGQTWMESGVSENAVSGHIQLIIP 221
+++ +DN EAR +++ C + ++SG GH ++I+P
Sbjct: 564 IITALDNVEARRYVDSRCLANLRPLLDSGTM--GTKGHTEVIVP 605
Score = 31.6 bits (70), Expect = 1.3
Identities = 19/70 (27%), Positives = 35/70 (50%)
Query: 69 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLFFQPHQAGLSKV 128
+K+ V + G+GG+G A+ L GI + + D +K + ++ FF ++K
Sbjct: 57 QKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQAWDLGTNFFLSEDDVVNKR 116
Query: 129 QAAEHTLRNI 138
AE L++I
Sbjct: 117 NRAEAVLKHI 126
>gi|38045948 ubiquitin-like modifier activating enzyme 7 [Homo
sapiens]
Length = 1012
Score = 50.4 bits (119), Expect = 3e-06
Identities = 40/149 (26%), Positives = 66/149 (44%), Gaps = 20/149 (13%)
Query: 69 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGK-----LLLFDYDKVELANMNRLF-FQPHQ 122
EK+R +VG G +G ++ G+G L + D D +E +N++R F F+
Sbjct: 428 EKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQD 487
Query: 123 AGLSKVQAAEHTLRNINPDVLFEVHNYNIT-TVENF--QHFMDRISNGGLEEGKPVDLVL 179
G K + A R +NPD+ Y + T E+ +F R VD V
Sbjct: 488 VGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSR-----------VDGVA 536
Query: 180 SCVDNFEARMTINTACNELGQTWMESGVS 208
+ +D+F+AR + C + +E+G S
Sbjct: 537 AALDSFQARRYVAARCTHYLKPLLEAGTS 565
Score = 35.0 bits (79), Expect = 0.12
Identities = 28/110 (25%), Positives = 53/110 (48%), Gaps = 4/110 (3%)
Query: 44 SSEVVDSNPYSRLMALKRMGIVSDYEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLF 103
+S+++D YSR + + + ++I+ V + G+ G+G+ A+ L G+G L L
Sbjct: 6 ASKLLDEELYSRQLYVLGSPAM---QRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLH 62
Query: 104 DYDKVELANMNRLFFQPHQ-AGLSKVQAAEHTLRNINPDVLFEVHNYNIT 152
D +++ F Q S+ +A++ L +N V VH +IT
Sbjct: 63 DPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDIT 112
>gi|38045942 ubiquitin-activating enzyme 3 isoform 1 [Homo sapiens]
Length = 463
Score = 47.8 bits (112), Expect = 2e-05
Identities = 61/258 (23%), Positives = 104/258 (40%), Gaps = 56/258 (21%)
Query: 3 ESVERLQQRVQELERELAQERSLQVPRSGDGGGGRVRIEKMSSEVVDSNPYSRLMALKRM 62
E E+ ++R++EL LA++ ++ GD G R + + S P++
Sbjct: 5 EEPEKKRRRIEEL---LAEKMAVD-GGCGDTGDWEGRWNHVKKFLERSGPFTH------- 53
Query: 63 GIVSDYEK--------IRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMN 114
D+E + T V ++G GG+G + L G ++ + D D ++++N+N
Sbjct: 54 ---PDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLN 110
Query: 115 RLF-FQPHQAGLSKVQAAEHTLRNINPDVLFEVHNYNITTVEN-FQHFMDRISNGGLEEG 172
R F F+P G K + A L + V N N+ N Q F D
Sbjct: 111 RQFLFRPKDIGRPKAEVAAEFLND-------RVPNCNVVPHFNKIQDFNDTFY------- 156
Query: 173 KPVDLVLSCVDNFEARMTINTACNELGQTWMESGVSE------------NAVSGHIQLII 220
+ +++ +D+ AR IN L E GV + G+ ++I+
Sbjct: 157 RQFHIIVCGLDSIIARRWINGMLISLLN--YEDGVLDPSSIVPLIDGGTEGFKGNARVIL 214
Query: 221 PGESACFACA----PPLV 234
PG +AC C PP V
Sbjct: 215 PGMTACIECTLELYPPQV 232
>gi|38045944 ubiquitin-activating enzyme 3 isoform 2 [Homo sapiens]
Length = 449
Score = 46.6 bits (109), Expect = 4e-05
Identities = 46/180 (25%), Positives = 74/180 (41%), Gaps = 34/180 (18%)
Query: 73 TFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLF-FQPHQAGLSKVQAA 131
T V ++G GG+G + L G ++ + D D ++++N+NR F F+P G K + A
Sbjct: 55 TCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVA 114
Query: 132 EHTLRNINPDVLFEVHNYNITTVEN-FQHFMDRISNGGLEEGKPVDLVLSCVDNFEARMT 190
L + V N N+ N Q F D + +++ +D+ AR
Sbjct: 115 AEFLND-------RVPNCNVVPHFNKIQDFNDTFY-------RQFHIIVCGLDSIIARRW 160
Query: 191 INTACNELGQTWMESGVSE------------NAVSGHIQLIIPGESACFACA----PPLV 234
IN L E GV + G+ ++I+PG +AC C PP V
Sbjct: 161 INGMLISLLN--YEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQV 218
>gi|33946313 ninein isoform 4 [Homo sapiens]
Length = 2096
Score = 37.0 bits (84), Expect = 0.032
Identities = 18/48 (37%), Positives = 32/48 (66%), Gaps = 1/48 (2%)
Query: 304 DDRNCRKQQEEYKKKVAALPKQEVIQEEEEIIHEDNEWGIELVSEVSE 351
++ N RK EEYK+++AAL K E+ +E E+I+ + + +EL E+ +
Sbjct: 421 NEYNLRKLDEEYKERIAAL-KNELRKEREQILQQAGKQRLELEQEIEK 467
Score = 28.9 bits (63), Expect = 8.7
Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 4/69 (5%)
Query: 1 MAESVERLQQRVQELERELAQERSLQVPRSGDGGGGRVRIEKMSSEVVDSNPYSRLMALK 60
MA + RLQQR+Q+LE L L P + G + E + N ++ +
Sbjct: 1090 MATEISRLQQRLQKLEPGLVMSSCLDEPATEFFGNTAEQTEPF----LQQNRTKQVEGVT 1145
Query: 61 RMGIVSDYE 69
R ++SD E
Sbjct: 1146 RRHVLSDLE 1154
>gi|33946321 ninein isoform 5 [Homo sapiens]
Length = 2090
Score = 37.0 bits (84), Expect = 0.032
Identities = 18/48 (37%), Positives = 32/48 (66%), Gaps = 1/48 (2%)
Query: 304 DDRNCRKQQEEYKKKVAALPKQEVIQEEEEIIHEDNEWGIELVSEVSE 351
++ N RK EEYK+++AAL K E+ +E E+I+ + + +EL E+ +
Sbjct: 415 NEYNLRKLDEEYKERIAAL-KNELRKEREQILQQAGKQRLELEQEIEK 461
Score = 28.9 bits (63), Expect = 8.7
Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 4/69 (5%)
Query: 1 MAESVERLQQRVQELERELAQERSLQVPRSGDGGGGRVRIEKMSSEVVDSNPYSRLMALK 60
MA + RLQQR+Q+LE L L P + G + E + N ++ +
Sbjct: 1084 MATEISRLQQRLQKLEPGLVMSSCLDEPATEFFGNTAEQTEPF----LQQNRTKQVEGVT 1139
Query: 61 RMGIVSDYE 69
R ++SD E
Sbjct: 1140 RRHVLSDLE 1148
>gi|148536871 ninein isoform 1 [Homo sapiens]
Length = 2046
Score = 37.0 bits (84), Expect = 0.032
Identities = 18/48 (37%), Positives = 32/48 (66%), Gaps = 1/48 (2%)
Query: 304 DDRNCRKQQEEYKKKVAALPKQEVIQEEEEIIHEDNEWGIELVSEVSE 351
++ N RK EEYK+++AAL K E+ +E E+I+ + + +EL E+ +
Sbjct: 415 NEYNLRKLDEEYKERIAAL-KNELRKEREQILQQAGKQRLELEQEIEK 461
Score = 28.9 bits (63), Expect = 8.7
Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 4/69 (5%)
Query: 1 MAESVERLQQRVQELERELAQERSLQVPRSGDGGGGRVRIEKMSSEVVDSNPYSRLMALK 60
MA + RLQQR+Q+LE L L P + G + E + N ++ +
Sbjct: 1084 MATEISRLQQRLQKLEPGLVMSSCLDEPATEFFGNTAEQTEPF----LQQNRTKQVEGVT 1139
Query: 61 RMGIVSDYE 69
R ++SD E
Sbjct: 1140 RRHVLSDLE 1148
>gi|148536869 ninein isoform 2 [Homo sapiens]
Length = 2133
Score = 37.0 bits (84), Expect = 0.032
Identities = 18/48 (37%), Positives = 32/48 (66%), Gaps = 1/48 (2%)
Query: 304 DDRNCRKQQEEYKKKVAALPKQEVIQEEEEIIHEDNEWGIELVSEVSE 351
++ N RK EEYK+++AAL K E+ +E E+I+ + + +EL E+ +
Sbjct: 415 NEYNLRKLDEEYKERIAAL-KNELRKEREQILQQAGKQRLELEQEIEK 461
Score = 28.9 bits (63), Expect = 8.7
Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 4/69 (5%)
Query: 1 MAESVERLQQRVQELERELAQERSLQVPRSGDGGGGRVRIEKMSSEVVDSNPYSRLMALK 60
MA + RLQQR+Q+LE L L P + G + E + N ++ +
Sbjct: 1084 MATEISRLQQRLQKLEPGLVMSSCLDEPATEFFGNTAEQTEPF----LQQNRTKQVEGVT 1139
Query: 61 RMGIVSDYE 69
R ++SD E
Sbjct: 1140 RRHVLSDLE 1148
>gi|225543288 SUMO1 activating enzyme subunit 1 isoform c [Homo
sapiens]
Length = 266
Score = 34.7 bits (78), Expect = 0.16
Identities = 21/84 (25%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query: 69 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLF-FQPHQAGLSK 127
+++R V +VG+ G+G+ A+ L G+ L + D+++V + F + G ++
Sbjct: 32 KRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNR 91
Query: 128 VQAAEHTLRNINPDVLFEVHNYNI 151
+A+ +N+NP V +V +I
Sbjct: 92 AEASLERAQNLNPMVDVKVDTEDI 115
>gi|225543285 SUMO1 activating enzyme subunit 1 isoform b [Homo
sapiens]
Length = 299
Score = 34.7 bits (78), Expect = 0.16
Identities = 21/84 (25%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query: 69 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLF-FQPHQAGLSK 127
+++R V +VG+ G+G+ A+ L G+ L + D+++V + F + G ++
Sbjct: 32 KRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNR 91
Query: 128 VQAAEHTLRNINPDVLFEVHNYNI 151
+A+ +N+NP V +V +I
Sbjct: 92 AEASLERAQNLNPMVDVKVDTEDI 115
>gi|4885585 SUMO1 activating enzyme subunit 1 isoform a [Homo
sapiens]
Length = 346
Score = 34.7 bits (78), Expect = 0.16
Identities = 21/84 (25%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query: 69 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLF-FQPHQAGLSK 127
+++R V +VG+ G+G+ A+ L G+ L + D+++V + F + G ++
Sbjct: 32 KRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNR 91
Query: 128 VQAAEHTLRNINPDVLFEVHNYNI 151
+A+ +N+NP V +V +I
Sbjct: 92 AEASLERAQNLNPMVDVKVDTEDI 115
>gi|7705473 SUMO1 activating enzyme subunit 1 isoform a [Homo
sapiens]
Length = 346
Score = 34.7 bits (78), Expect = 0.16
Identities = 21/84 (25%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query: 69 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLF-FQPHQAGLSK 127
+++R V +VG+ G+G+ A+ L G+ L + D+++V + F + G ++
Sbjct: 32 KRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNR 91
Query: 128 VQAAEHTLRNINPDVLFEVHNYNI 151
+A+ +N+NP V +V +I
Sbjct: 92 AEASLERAQNLNPMVDVKVDTEDI 115
>gi|87298939 hypothetical protein LOC131831 [Homo sapiens]
Length = 663
Score = 33.1 bits (74), Expect = 0.46
Identities = 17/46 (36%), Positives = 29/46 (63%)
Query: 309 RKQQEEYKKKVAALPKQEVIQEEEEIIHEDNEWGIELVSEVSEEEL 354
+K Q+E ++++ ++E ++EEEE + E+ E E EV EEEL
Sbjct: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEEL 60
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 32.7 bits (73), Expect = 0.60
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 5/59 (8%)
Query: 298 KPNPQCDDRNCRKQQEEYKKKVAALPKQEVIQEEEEIIHEDNEWGIELVSEVSEEELKN 356
K + +++ K++EE KKK K+EV QE+EE+ E E++SE E L +
Sbjct: 2270 KEEEEGEEKQVEKEEEEKKKKKKEKKKEEV-QEKEEVFEEKE----EIMSEEETESLSD 2323
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 32.3 bits (72), Expect = 0.78
Identities = 28/111 (25%), Positives = 58/111 (52%), Gaps = 13/111 (11%)
Query: 294 TMSMKPNPQCDDRNCRKQQEEYKK-KVAALPKQEVIQEEEEIIHEDNEWGIELVSEVSEE 352
T+SM+ P + ++++ + +K K +AL +++ + EE+++I E+ E + ++
Sbjct: 1179 TLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEE-----EKIRSEEKK 1233
Query: 353 ELKNFSGPVPD----LPEGITVAYTIPKKQEDSVTELTVEDSGESLEDLMA 399
L P P+ LPE T A P++Q+ + + V+ + E LE +A
Sbjct: 1234 PLLEEKKPTPEDKKLLPEAKTSA---PEEQKHDLLKSQVQIAEEKLEGRVA 1281
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 32.3 bits (72), Expect = 0.78
Identities = 28/111 (25%), Positives = 58/111 (52%), Gaps = 13/111 (11%)
Query: 294 TMSMKPNPQCDDRNCRKQQEEYKK-KVAALPKQEVIQEEEEIIHEDNEWGIELVSEVSEE 352
T+SM+ P + ++++ + +K K +AL +++ + EE+++I E+ E + ++
Sbjct: 1179 TLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEE-----EKIRSEEKK 1233
Query: 353 ELKNFSGPVPD----LPEGITVAYTIPKKQEDSVTELTVEDSGESLEDLMA 399
L P P+ LPE T A P++Q+ + + V+ + E LE +A
Sbjct: 1234 PLLEEKKPTPEDKKLLPEAKTSA---PEEQKHDLLKSQVQIAEEKLEGRVA 1281
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 32.0 bits (71), Expect = 1.0
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 8/78 (10%)
Query: 310 KQQEEYKKKVAALPKQEVIQEEEEIIHEDNEWGIELVSEVSEEEL-------KNFSGPVP 362
+++E ++ LP++E I EEE + + E+ E V EEE+ PVP
Sbjct: 10129 EEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVP 10188
Query: 363 DLPEGIT-VAYTIPKKQE 379
++ + +T IPKK+E
Sbjct: 10189 EIKKKVTEKKVVIPKKEE 10206
Score = 30.4 bits (67), Expect = 3.0
Identities = 16/43 (37%), Positives = 26/43 (60%)
Query: 311 QQEEYKKKVAALPKQEVIQEEEEIIHEDNEWGIELVSEVSEEE 353
Q+EE + +P++EV+ EEEE++ E+ E E + EEE
Sbjct: 10103 QEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEE 10145
Score = 28.9 bits (63), Expect = 8.7
Identities = 20/78 (25%), Positives = 37/78 (47%), Gaps = 20/78 (25%)
Query: 311 QQEEYKKKVAALPKQEVIQEEEEIIHEDNEWGIE---------LVSEVSEEELKNFSGPV 361
++ ++++V ++ +++EEEE IHE+ E+ E V EV + + PV
Sbjct: 9906 EEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPV 9965
Query: 362 PDLPEGITVAYTIPKKQE 379
P +PKK+E
Sbjct: 9966 P-----------VPKKKE 9972
>gi|4826724 zygin 1 isoform 1 [Homo sapiens]
Length = 392
Score = 31.2 bits (69), Expect = 1.7
Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 9/129 (6%)
Query: 270 LKFLLNFGTVSFYLGYNAMQDFFPTMSMKPNPQCDDRNCRKQQEEYKKKVAALPKQEVIQ 329
L L NF S + + +M+D K N C + + +A + Q IQ
Sbjct: 43 LSELENFS--SEIISFKSMEDLVNEFDEKLNV------CFRNYNAKTENLAPVKNQLQIQ 94
Query: 330 EEEEIIHEDNEWGIELVSEVSEEELKNFSGPVPDLPEGITVAYTIPKKQEDSVTELTVED 389
EEEE + ++ W L +++ P + G I +K+E+ E + D
Sbjct: 95 EEEETLQDEEVWD-ALTDNYIPSLSEDWRDPNIEALNGNCSDTEIHEKEEEEFNEKSEND 153
Query: 390 SGESLEDLM 398
SG + E L+
Sbjct: 154 SGINEEPLL 162
>gi|16418451 hypothetical protein LOC116328 [Homo sapiens]
Length = 427
Score = 31.2 bits (69), Expect = 1.7
Identities = 24/100 (24%), Positives = 52/100 (52%), Gaps = 13/100 (13%)
Query: 293 PTMSMKPNPQCDDRNCRKQQEEYKKKVAALPKQEVIQE---------EEEIIHEDNEWGI 343
P S+K P+ ++ ++QQ+++KK +AA+ Q+ + EE+I +ED+ +
Sbjct: 199 PAGSLKMEPK--NKGLKQQQQQHKKLLAAMLSQDSFESIHSPTPSVTEEDIDNEDD--AM 254
Query: 344 ELVSEVSEEELKNFSGPVPDLPEGITVAYTIPKKQEDSVT 383
EL+ ++++ ++ + VP + T P + + VT
Sbjct: 255 ELLEDLNDLRMEGVTTLVPSGSKFNQGRPTYPAEPQAKVT 294
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 30.8 bits (68), Expect = 2.3
Identities = 29/101 (28%), Positives = 45/101 (44%), Gaps = 13/101 (12%)
Query: 309 RKQQEEYKKKVAALPKQEVIQEEEEIIHEDNEWGIELVSEVSEEELKNFSGPVPDLPEGI 368
R Q E K+ + ++E +EEEE E+ E E E EEE +N P L +
Sbjct: 1058 RGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQ 1117
Query: 369 TVA------YTIPKKQ-------EDSVTELTVEDSGESLED 396
+VA + + KK+ SVT T+ ++ E L +
Sbjct: 1118 SVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNE 1158
>gi|66363686 NEDD8 activating enzyme E1 subunit 1 isoform b [Homo
sapiens]
Length = 528
Score = 30.8 bits (68), Expect = 2.3
Identities = 19/75 (25%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 69 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANM-NRLFFQPHQAGLSK 127
E + + V ++ G+ + L GIG + D ++V + N F Q G ++
Sbjct: 20 EALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSSIGKNR 79
Query: 128 VQAAEHTLRNINPDV 142
+AA L+ +N DV
Sbjct: 80 AEAAMEFLQELNSDV 94
>gi|4502169 NEDD8 activating enzyme E1 subunit 1 isoform a [Homo
sapiens]
Length = 534
Score = 30.8 bits (68), Expect = 2.3
Identities = 19/75 (25%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 69 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANM-NRLFFQPHQAGLSK 127
E + + V ++ G+ + L GIG + D ++V + N F Q G ++
Sbjct: 26 EALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSSIGKNR 85
Query: 128 VQAAEHTLRNINPDV 142
+AA L+ +N DV
Sbjct: 86 AEAAMEFLQELNSDV 100
>gi|53831997 suppressor of cytokine signaling 7 [Homo sapiens]
Length = 581
Score = 30.8 bits (68), Expect = 2.3
Identities = 14/43 (32%), Positives = 21/43 (48%)
Query: 5 VERLQQRVQELERELAQERSLQVPRSGDGGGGRVRIEKMSSEV 47
+E L+ + LE E L P G GGGGR+ ++ E+
Sbjct: 117 LEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPEL 159
>gi|94536811 NEDD4-like ubiquitin-protein ligase 1 [Homo sapiens]
Length = 1606
Score = 30.4 bits (67), Expect = 3.0
Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 9/43 (20%)
Query: 3 ESVERLQQRVQELERELAQERSL---------QVPRSGDGGGG 36
+ +E+L +R Q ++R +A ERS Q P G GGGG
Sbjct: 876 QQMEQLNRRYQNIQRTIATERSEEDSGSQSCEQAPAGGGGGGG 918
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,666,766
Number of Sequences: 37866
Number of extensions: 655918
Number of successful extensions: 3203
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 3070
Number of HSP's gapped (non-prelim): 138
length of query: 404
length of database: 18,247,518
effective HSP length: 105
effective length of query: 299
effective length of database: 14,271,588
effective search space: 4267204812
effective search space used: 4267204812
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.