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Search of human proteins with 13375930
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo
sapiens]
(350 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens] 738 0.0
gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens] 435 e-122
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 155 5e-38
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 155 5e-38
gi|224465233 euchromatic histone-lysine N-methyltransferase 1 is... 150 2e-36
gi|194306650 SET domain and mariner transposase fusion [Homo sap... 130 2e-30
gi|27477095 nuclear receptor binding SET domain protein 1 isofor... 109 4e-24
gi|19923586 nuclear receptor binding SET domain protein 1 isofor... 109 4e-24
gi|197313748 SET domain containing 2 [Homo sapiens] 104 1e-22
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 101 1e-21
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 101 1e-21
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 101 1e-21
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor... 101 1e-21
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens] 97 2e-20
gi|19923202 enhancer of zeste homolog 1 [Homo sapiens] 96 4e-20
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens] 96 4e-20
gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens] 94 2e-19
gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens] 94 2e-19
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 90 3e-18
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 84 1e-16
gi|224177467 SET domain, bifurcated 1 isoform 1 [Homo sapiens] 81 2e-15
gi|210032580 SET domain containing 1B [Homo sapiens] 81 2e-15
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 80 4e-15
gi|224177469 SET domain, bifurcated 1 isoform 2 [Homo sapiens] 79 5e-15
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 75 9e-14
gi|55741677 SET domain containing 1A [Homo sapiens] 74 2e-13
gi|238624099 SET domain, bifurcated 2 isoform b [Homo sapiens] 66 4e-11
gi|238624095 SET domain, bifurcated 2 isoform a [Homo sapiens] 66 4e-11
gi|45356743 SET domain-containing 8 [Homo sapiens] 64 3e-10
gi|122937492 SET domain containing 5 [Homo sapiens] 50 2e-06
>gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens]
Length = 350
Score = 738 bits (1905), Expect = 0.0
Identities = 350/350 (100%), Positives = 350/350 (100%)
Query: 1 MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQQFSNDKHNYLSQVKKGKAITPKDNNKTLK 60
MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQQFSNDKHNYLSQVKKGKAITPKDNNKTLK
Sbjct: 1 MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQQFSNDKHNYLSQVKKGKAITPKDNNKTLK 60
Query: 61 PAIAEYIVKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPG 120
PAIAEYIVKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPG
Sbjct: 61 PAIAEYIVKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPG 120
Query: 121 ISLVNEATFGCSCTDCFFQKCCPAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCGPDCP 180
ISLVNEATFGCSCTDCFFQKCCPAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCGPDCP
Sbjct: 121 ISLVNEATFGCSCTDCFFQKCCPAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCGPDCP 180
Query: 181 NRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNK 240
NRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNK
Sbjct: 181 NRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNK 240
Query: 241 GITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTR 300
GITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTR
Sbjct: 241 GITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTR 300
Query: 301 TINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN 350
TINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN
Sbjct: 301 TINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN 350
>gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens]
Length = 412
Score = 435 bits (1118), Expect = e-122
Identities = 215/360 (59%), Positives = 261/360 (72%), Gaps = 18/360 (5%)
Query: 2 EYYLVKWKGWPDSTNTWEPLQNLKCPLLLQQFSNDKHNYLSQVKKGKAITPKDNNKTLKP 61
EYYLVKW+G+PDS +TWEP QNLKC +L+QF D L + + ++ TP+ L P
Sbjct: 58 EYYLVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLR-RHHRSKTPRH----LDP 112
Query: 62 AIAEYIVKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPGI 121
++A Y+V+KAKQR AL+RW+ ELN +++H G I VEN VDL+GPP F YINEY+ GI
Sbjct: 113 SLANYLVQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGI 172
Query: 122 SLVNEATFGCSCTDCFFQK---CCPAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCGPD 178
+L N+ GC C DC + CCP + AYN Q+++ G PIYECNSRC+CG D
Sbjct: 173 TL-NQVAVGCECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCGYD 231
Query: 179 CPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYD 238
CPNR+VQKG +Y LCIFRT +GRGWGV+TL KI++ SFVMEYVGE+ITSEEAERRGQ YD
Sbjct: 232 CPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYD 291
Query: 239 NKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFS 298
+G TYLFDLDY D +TVDAA YGN+SHFVNHSCDPNLQV+NVFIDNLD RLPRIA F+
Sbjct: 292 RQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFA 351
Query: 299 TRTINAGEELTFDYQMK-GSGDISSDSIDHS--------PAKKRVRTVCKCGAVTCRGYL 349
TRTI AGEELTFDY M+ D+ S +D + KKRVR CKCG +CR YL
Sbjct: 352 TRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYL 411
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2 isoform
b [Homo sapiens]
Length = 1176
Score = 155 bits (392), Expect = 5e-38
Identities = 98/258 (37%), Positives = 137/258 (53%), Gaps = 29/258 (11%)
Query: 98 NTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCT---DCFFQKCCPAEAGVLLAYNK 154
N VD E P D+ YI+E +++ T CT DC C + + Y+K
Sbjct: 905 NGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDK 964
Query: 155 NQQI-----KIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLV 209
+ ++ KI P I+ECN C C +C NR+VQ G + L ++RT+ GWGV+ L
Sbjct: 965 DGRLLQEFNKIEPPL-IFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAK-MGWGVRALQ 1022
Query: 210 KIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDE-FTVDAARYGNVSHF 268
I + +F+ EYVGE+I+ EA+ R + +YLFDLD + E + +DA YGN+S F
Sbjct: 1023 TIPQGTFICEYVGELISDAEADVR------EDDSYLFDLDNKDGEVYCIDARYYGNISRF 1076
Query: 269 VNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHS 328
+NH CDPN+ VF+ + D R PRIA FS+R I GEEL FDY GD D
Sbjct: 1077 INHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDY-----GDRFWDI---- 1127
Query: 329 PAKKRVRTVCKCGAVTCR 346
K C+CG+ C+
Sbjct: 1128 ---KSKYFTCQCGSEKCK 1142
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2 isoform
a [Homo sapiens]
Length = 1210
Score = 155 bits (392), Expect = 5e-38
Identities = 98/258 (37%), Positives = 137/258 (53%), Gaps = 29/258 (11%)
Query: 98 NTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCT---DCFFQKCCPAEAGVLLAYNK 154
N VD E P D+ YI+E +++ T CT DC C + + Y+K
Sbjct: 939 NGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDK 998
Query: 155 NQQI-----KIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLV 209
+ ++ KI P I+ECN C C +C NR+VQ G + L ++RT+ GWGV+ L
Sbjct: 999 DGRLLQEFNKIEPPL-IFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAK-MGWGVRALQ 1056
Query: 210 KIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDE-FTVDAARYGNVSHF 268
I + +F+ EYVGE+I+ EA+ R + +YLFDLD + E + +DA YGN+S F
Sbjct: 1057 TIPQGTFICEYVGELISDAEADVR------EDDSYLFDLDNKDGEVYCIDARYYGNISRF 1110
Query: 269 VNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHS 328
+NH CDPN+ VF+ + D R PRIA FS+R I GEEL FDY GD D
Sbjct: 1111 INHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDY-----GDRFWDI---- 1161
Query: 329 PAKKRVRTVCKCGAVTCR 346
K C+CG+ C+
Sbjct: 1162 ---KSKYFTCQCGSEKCK 1176
>gi|224465233 euchromatic histone-lysine N-methyltransferase 1 isoform
1 [Homo sapiens]
Length = 1298
Score = 150 bits (379), Expect = 2e-36
Identities = 95/257 (36%), Positives = 136/257 (52%), Gaps = 27/257 (10%)
Query: 98 NTVDLEGPPSDFYYINEYKPAPGISLVNEATF--GCSCTD-CFFQKCCPAEAGVLLAYNK 154
N VD E PS++ Y+++ +++ T C C D C C + + Y+K
Sbjct: 1027 NAVDSEPCPSNYKYVSQNCVTSPMNIDRNITHLQYCVCIDDCSSSNCMCGQLSMRCWYDK 1086
Query: 155 NQQI----KIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVK 210
+ ++ + I+ECN C C +C NR+VQ G + L ++RT + GWGV++L
Sbjct: 1087 DGRLLPEFNMAEPPLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTRD-MGWGVRSLQD 1145
Query: 211 IKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDE-FTVDAARYGNVSHFV 269
I +FV EYVGE+I+ EA+ R + +YLFDLD + E + +DA YGNVS F+
Sbjct: 1146 IPPGTFVCEYVGELISDSEADVREED------SYLFDLDNKDGEVYCIDARFYGNVSRFI 1199
Query: 270 NHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSP 329
NH C+PNL VF+ + D R PRIA FSTR I AGE+L FDY + DI
Sbjct: 1200 NHHCEPNLVPVRVFMAHQDLRFPRIAFFSTRLIEAGEQLGFDYGER-FWDIKGKLFS--- 1255
Query: 330 AKKRVRTVCKCGAVTCR 346
C+CG+ CR
Sbjct: 1256 --------CRCGSPKCR 1264
>gi|194306650 SET domain and mariner transposase fusion [Homo
sapiens]
Length = 684
Score = 130 bits (327), Expect = 2e-30
Identities = 88/261 (33%), Positives = 134/261 (51%), Gaps = 27/261 (10%)
Query: 106 PSDFYYINEYKPAPGISL-VNEATF-GCSC--TDCFFQKCCPAEAGVLLAYNKNQQIK-I 160
P+ F Y ++ PG + + TF GC C T C C G Y+ N ++ I
Sbjct: 48 PAPFQYTPDHVVGPGADIDPTQITFPGCICVKTPCLPGTCSCLRHGE--NYDDNSCLRDI 105
Query: 161 PPG----TPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSF 216
G P++ECN C+C C NR+VQKG Q+ +F+T + +GWG++TL I + F
Sbjct: 106 GSGGKYAEPVFECNVLCRCSDHCRNRVVQKGLQFHFQVFKT-HKKGWGLRTLEFIPKGRF 164
Query: 217 VMEYVGEVITSEEAERRGQFYDNKGITYLFDL-----DYESDEFTVDAARYGNVSHFVNH 271
V EY GEV+ E +RR Y+ + + + E VD GN+ F+NH
Sbjct: 165 VCEYAGEVLGFSEVQRRIHLQTKSDSNYIIAIREHVYNGQVMETFVDPTYIGNIGRFLNH 224
Query: 272 SCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSG-DISSDS--IDHS 328
SC+PNL + V ID++ +P++ALF+ + I EEL++DY + +S D +DH
Sbjct: 225 SCEPNLLMIPVRIDSM---VPKLALFAAKDIVPEEELSYDYSGRYLNLTVSEDKERLDHG 281
Query: 329 PAKKRVRTVCKCGAVTCRGYL 349
++R C CGA +C +L
Sbjct: 282 ----KLRKPCYCGAKSCTAFL 298
>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
[Homo sapiens]
Length = 2427
Score = 109 bits (272), Expect = 4e-24
Identities = 69/185 (37%), Positives = 94/185 (50%), Gaps = 21/185 (11%)
Query: 166 IYECNSR-CQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEV 224
+YEC+ C G C N+ K + IFRT RGWG++T IK+ FV EYVGE+
Sbjct: 1648 LYECHPTVCPAGGRCQNQCFSKRQYPEVEIFRTLQ-RGWGLRTKTDIKKGEFVNEYVGEL 1706
Query: 225 ITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFI 284
I EE R ++ IT + L + D +DA GN + F+NH C PN + +
Sbjct: 1707 IDEEECRARIRYAQEHDITNFYMLTLDKDRI-IDAGPKGNYARFMNHCCQPNCETQKWSV 1765
Query: 285 DNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVT 344
N DT R+ LF+ I AG ELTF+Y ++ G+ +TVCKCGA
Sbjct: 1766 -NGDT---RVGLFALSDIKAGTELTFNYNLECLGN--------------GKTVCKCGAPN 1807
Query: 345 CRGYL 349
C G+L
Sbjct: 1808 CSGFL 1812
>gi|19923586 nuclear receptor binding SET domain protein 1 isoform b
[Homo sapiens]
Length = 2696
Score = 109 bits (272), Expect = 4e-24
Identities = 69/185 (37%), Positives = 94/185 (50%), Gaps = 21/185 (11%)
Query: 166 IYECNSR-CQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEV 224
+YEC+ C G C N+ K + IFRT RGWG++T IK+ FV EYVGE+
Sbjct: 1917 LYECHPTVCPAGGRCQNQCFSKRQYPEVEIFRTLQ-RGWGLRTKTDIKKGEFVNEYVGEL 1975
Query: 225 ITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFI 284
I EE R ++ IT + L + D +DA GN + F+NH C PN + +
Sbjct: 1976 IDEEECRARIRYAQEHDITNFYMLTLDKDRI-IDAGPKGNYARFMNHCCQPNCETQKWSV 2034
Query: 285 DNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVT 344
N DT R+ LF+ I AG ELTF+Y ++ G+ +TVCKCGA
Sbjct: 2035 -NGDT---RVGLFALSDIKAGTELTFNYNLECLGN--------------GKTVCKCGAPN 2076
Query: 345 CRGYL 349
C G+L
Sbjct: 2077 CSGFL 2081
>gi|197313748 SET domain containing 2 [Homo sapiens]
Length = 2564
Score = 104 bits (259), Expect = 1e-22
Identities = 65/183 (35%), Positives = 97/183 (53%), Gaps = 22/183 (12%)
Query: 168 ECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITS 227
EC+SRC G C NR Q+ + + T +GWG++ + +FV+EY GEV+
Sbjct: 1528 ECSSRCPNGDYCSNRRFQRKQHADVEVILTEK-KGWGLRAAKDLPSNTFVLEYCGEVLDH 1586
Query: 228 EEAERRGQFY-DNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDN 286
+E + R + Y NK I Y F + ++DE +DA + GN S F+NHSC+PN + ++
Sbjct: 1587 KEFKARVKEYARNKNIHYYF-MALKNDEI-IDATQKGNCSRFMNHSCEPNCETQKWTVNG 1644
Query: 287 LDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCR 346
R+ F+T+ + +G ELTFDYQ + G A+K C CG+ CR
Sbjct: 1645 ----QLRVGFFTTKLVPSGSELTFDYQFQRYG---------KEAQK-----CFCGSANCR 1686
Query: 347 GYL 349
GYL
Sbjct: 1687 GYL 1689
>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 101 bits (251), Expect = 1e-21
Identities = 65/185 (35%), Positives = 93/185 (50%), Gaps = 21/185 (11%)
Query: 166 IYECNSR-CQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEV 224
++EC+ + C G C N+ K I +T +G+GWG+ I++ FV EYVGE+
Sbjct: 1038 MFECHPQVCPAGEFCQNQCFTKRQYPETKIIKT-DGKGWGLVAKRDIRKGEFVNEYVGEL 1096
Query: 225 ITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFI 284
I EE R + IT+ + L + D +DA GN S F+NHSC PN + +
Sbjct: 1097 IDEEECMARIKHAHENDITHFYMLTIDKDRI-IDAGPKGNYSRFMNHSCQPNCETLKWTV 1155
Query: 285 DNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVT 344
N DT R+ LF+ I AG ELTF+Y + G+ +TVC+CGA
Sbjct: 1156 -NGDT---RVGLFAVCDIPAGTELTFNYNLDCLGN--------------EKTVCRCGASN 1197
Query: 345 CRGYL 349
C G+L
Sbjct: 1198 CSGFL 1202
>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 101 bits (251), Expect = 1e-21
Identities = 65/185 (35%), Positives = 93/185 (50%), Gaps = 21/185 (11%)
Query: 166 IYECNSR-CQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEV 224
++EC+ + C G C N+ K I +T +G+GWG+ I++ FV EYVGE+
Sbjct: 1038 MFECHPQVCPAGEFCQNQCFTKRQYPETKIIKT-DGKGWGLVAKRDIRKGEFVNEYVGEL 1096
Query: 225 ITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFI 284
I EE R + IT+ + L + D +DA GN S F+NHSC PN + +
Sbjct: 1097 IDEEECMARIKHAHENDITHFYMLTIDKDRI-IDAGPKGNYSRFMNHSCQPNCETLKWTV 1155
Query: 285 DNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVT 344
N DT R+ LF+ I AG ELTF+Y + G+ +TVC+CGA
Sbjct: 1156 -NGDT---RVGLFAVCDIPAGTELTFNYNLDCLGN--------------EKTVCRCGASN 1197
Query: 345 CRGYL 349
C G+L
Sbjct: 1198 CSGFL 1202
>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 101 bits (251), Expect = 1e-21
Identities = 65/185 (35%), Positives = 93/185 (50%), Gaps = 21/185 (11%)
Query: 166 IYECNSR-CQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEV 224
++EC+ + C G C N+ K I +T +G+GWG+ I++ FV EYVGE+
Sbjct: 1038 MFECHPQVCPAGEFCQNQCFTKRQYPETKIIKT-DGKGWGLVAKRDIRKGEFVNEYVGEL 1096
Query: 225 ITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFI 284
I EE R + IT+ + L + D +DA GN S F+NHSC PN + +
Sbjct: 1097 IDEEECMARIKHAHENDITHFYMLTIDKDRI-IDAGPKGNYSRFMNHSCQPNCETLKWTV 1155
Query: 285 DNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVT 344
N DT R+ LF+ I AG ELTF+Y + G+ +TVC+CGA
Sbjct: 1156 -NGDT---RVGLFAVCDIPAGTELTFNYNLDCLGN--------------EKTVCRCGASN 1197
Query: 345 CRGYL 349
C G+L
Sbjct: 1198 CSGFL 1202
>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 101 bits (251), Expect = 1e-21
Identities = 65/185 (35%), Positives = 93/185 (50%), Gaps = 21/185 (11%)
Query: 166 IYECNSR-CQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEV 224
++EC+ + C G C N+ K I +T +G+GWG+ I++ FV EYVGE+
Sbjct: 1038 MFECHPQVCPAGEFCQNQCFTKRQYPETKIIKT-DGKGWGLVAKRDIRKGEFVNEYVGEL 1096
Query: 225 ITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFI 284
I EE R + IT+ + L + D +DA GN S F+NHSC PN + +
Sbjct: 1097 IDEEECMARIKHAHENDITHFYMLTIDKDRI-IDAGPKGNYSRFMNHSCQPNCETLKWTV 1155
Query: 285 DNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVT 344
N DT R+ LF+ I AG ELTF+Y + G+ +TVC+CGA
Sbjct: 1156 -NGDT---RVGLFAVCDIPAGTELTFNYNLDCLGN--------------EKTVCRCGASN 1197
Query: 345 CRGYL 349
C G+L
Sbjct: 1198 CSGFL 1202
>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
Length = 2964
Score = 97.1 bits (240), Expect = 2e-20
Identities = 91/323 (28%), Positives = 152/323 (47%), Gaps = 51/323 (15%)
Query: 34 SNDKHNYLSQVKKGKA-ITPKDNNKTLKPA---IAEYIVKKAKQRIALQRWQDELNRRKN 89
+ D + L Q+KK K TP ++ L PA + +Y+ +K RI Q D L + K+
Sbjct: 2001 TTDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHVGKYLRQK---RIDFQLPYDILWQWKH 2057
Query: 90 HKGMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQKCCPAEAGVL 149
++ ++ + V L Y+ + KP G T C D +K C +
Sbjct: 2058 NQ--LYKKPDVPLYKKIRSNVYV-DVKPLSGYEAT---TCNCKKPDDDTRKGCVDDC--- 2108
Query: 150 LAYNKNQQIKIPPGTPIYECN-SRCQCGPDCPNRIVQKGTQYSLCIFR-TSNGRGWGVKT 207
N+ I EC+ + C CG C N+ +Q+ ++ C+ R + +GWG++T
Sbjct: 2109 ----LNRMI-------FAECSPNTCPCGEQCCNQRIQRH-EWVQCLERFRAEEKGWGIRT 2156
Query: 208 LVKIKRMSFVMEYVGEVITSEEAERRG-QFYDNKGITYLFDLDYESDEFTVDAARYGNVS 266
+K F++EY+GEV++ +E R + Y N Y +LD +D+ R GN +
Sbjct: 2157 KEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLD---SGMVIDSYRMGNEA 2213
Query: 267 HFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSID 326
F+NHSCDPN ++ ++ + RI L++ + + AG ELT+DY
Sbjct: 2214 RFINHSCDPNCEMQKWSVNG----VYRIGLYALKDMPAGTELTYDYNF------------ 2257
Query: 327 HSPAKKRVRTVCKCGAVTCRGYL 349
HS ++ + +CKCG CRG +
Sbjct: 2258 HSFNVEK-QQLCKCGFEKCRGII 2279
>gi|19923202 enhancer of zeste homolog 1 [Homo sapiens]
Length = 747
Score = 96.3 bits (238), Expect = 4e-20
Identities = 79/272 (29%), Positives = 126/272 (46%), Gaps = 47/272 (17%)
Query: 72 KQRIALQRWQDEL---NRRKNHKGMIFVENT--VDLEGPPSDFYYINEYKPAPGISLVNE 126
K+ + L+ DEL +++K K ++ + + L+ S N Y+P +
Sbjct: 474 KESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYN-YQPCDHPDRPCD 532
Query: 127 ATFGCSCTDCFFQKCCPAEAGVLLAYNKNQQIKIPPGTPIYECNSR---C-----QCGPD 178
+T C T F +K C N + Q + P +CN++ C +C PD
Sbjct: 533 STCPCIMTQNFCEKFCQC--------NPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPD 584
Query: 179 -----------------CPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYV 221
C N +Q+G + L + S+ GWG +++ F+ EY
Sbjct: 585 LCLTCGASEHWDCKVVSCKNCSIQRGLKKHL-LLAPSDVAGWGTFIKESVQKNEFISEYC 643
Query: 222 GEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFN 281
GE+I+ +EA+RRG+ YD ++LF+L +++F VDA R GN F NHS +PN
Sbjct: 644 GELISQDEADRRGKVYDKYMSSFLFNL---NNDFVVDATRKGNKIRFANHSVNPNCYAKV 700
Query: 282 VFIDNLDTRLPRIALFSTRTINAGEELTFDYQ 313
V ++ RI +F+ R I AGEEL FDY+
Sbjct: 701 VMVNGDH----RIGIFAKRAIQAGEELFFDYR 728
>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
Length = 1437
Score = 96.3 bits (238), Expect = 4e-20
Identities = 66/184 (35%), Positives = 88/184 (47%), Gaps = 21/184 (11%)
Query: 167 YECNSR-CQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVI 225
YEC+ + C G C N+ K I +T RGWG++T IK+ FV EYVGE+I
Sbjct: 1121 YECHPQVCPAGDRCQNQCFTKRLYPDAEIIKTER-RGWGLRTKRSIKKGEFVNEYVGELI 1179
Query: 226 TSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFID 285
EE R + +T + L D +DA GN S F+NHSC+PN + +
Sbjct: 1180 DEEECRLRIKRAHENSVTNFYMLTVTKDRI-IDAGPKGNYSRFMNHSCNPNCET-QKWTV 1237
Query: 286 NLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTC 345
N D R+ LF+ I AG ELTF+Y + G+ RT C CGA C
Sbjct: 1238 NGDV---RVGLFALCDIPAGMELTFNYNLDCLGN--------------GRTECHCGADNC 1280
Query: 346 RGYL 349
G+L
Sbjct: 1281 SGFL 1284
>gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens]
Length = 707
Score = 94.0 bits (232), Expect = 2e-19
Identities = 53/135 (39%), Positives = 80/135 (59%), Gaps = 8/135 (5%)
Query: 179 CPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYD 238
C N +Q+G++ L + S+ GWG+ +++ F+ EY GE+I+ +EA+RRG+ YD
Sbjct: 562 CKNCSIQRGSKKHL-LLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYD 620
Query: 239 NKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFS 298
++LF+L +++F VDA R GN F NHS +PN V + N D RI +F+
Sbjct: 621 KYMCSFLFNL---NNDFVVDATRKGNKIRFANHSVNPNCYA-KVMMVNGD---HRIGIFA 673
Query: 299 TRTINAGEELTFDYQ 313
R I GEEL FDY+
Sbjct: 674 KRAIQTGEELFFDYR 688
>gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens]
Length = 751
Score = 94.0 bits (232), Expect = 2e-19
Identities = 53/135 (39%), Positives = 80/135 (59%), Gaps = 8/135 (5%)
Query: 179 CPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYD 238
C N +Q+G++ L + S+ GWG+ +++ F+ EY GE+I+ +EA+RRG+ YD
Sbjct: 606 CKNCSIQRGSKKHL-LLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYD 664
Query: 239 NKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFS 298
++LF+L +++F VDA R GN F NHS +PN V + N D RI +F+
Sbjct: 665 KYMCSFLFNL---NNDFVVDATRKGNKIRFANHSVNPNCYA-KVMMVNGD---HRIGIFA 717
Query: 299 TRTINAGEELTFDYQ 313
R I GEEL FDY+
Sbjct: 718 KRAIQTGEELFFDYR 732
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 89.7 bits (221), Expect = 3e-18
Identities = 60/171 (35%), Positives = 92/171 (53%), Gaps = 24/171 (14%)
Query: 182 RIVQKGTQYSLCIFRTS-NGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNK 240
R ++K ++ ++ ++R+ +GRG K + M V+EY G VI S + ++R ++YD+K
Sbjct: 3821 RHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEM--VIEYAGNVIRSIQTDKREKYYDSK 3878
Query: 241 GI-TYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFST 299
GI Y+F +D D VDA +GN + F+NHSC+PN + ID I +F+
Sbjct: 3879 GIGCYMFRID---DSEVVDATMHGNAARFINHSCEPNCYSRVINIDG----QKHIVIFAM 3931
Query: 300 RTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN 350
R I GEELT+DY+ D+ + P C CGA CR +LN
Sbjct: 3932 RKIYRGEELTYDYKFP-----IEDASNKLP--------CNCGAKKCRKFLN 3969
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 84.3 bits (207), Expect = 1e-16
Identities = 59/171 (34%), Positives = 91/171 (53%), Gaps = 24/171 (14%)
Query: 182 RIVQKGTQYSLCIFRTS-NGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNK 240
R ++K ++ ++ ++R++ +GRG K + M V+EY G VI S ++R +FYD K
Sbjct: 2567 RHLKKTSKEAVGVYRSAIHGRGLFCKRNIDAGEM--VIEYSGIVIRSVLTDKREKFYDGK 2624
Query: 241 GI-TYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFST 299
GI Y+F +D D VDA +GN + F+NHSC+PN + ++ I +F+
Sbjct: 2625 GIGCYMFRMD---DFDVVDATMHGNAARFINHSCEPNCFSRVIHVEG----QKHIVIFAL 2677
Query: 300 RTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN 350
R I GEELT+DY+ D+ + P C CGA CR +LN
Sbjct: 2678 RRILRGEELTYDYKFP-----IEDASNKLP--------CNCGAKRCRRFLN 2715
>gi|224177467 SET domain, bifurcated 1 isoform 1 [Homo sapiens]
Length = 1291
Score = 80.9 bits (198), Expect = 2e-15
Identities = 50/149 (33%), Positives = 73/149 (48%), Gaps = 23/149 (15%)
Query: 201 RGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAA 260
RG+ +K+ I S M V + ++ + QFYD + Y+ D E
Sbjct: 1165 RGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQFYDGEESCYIIDAKLE--------- 1215
Query: 261 RYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDI 320
GN+ ++NHSC PNL V NVF+D D R P +A F+++ I AG ELT+DY + G +
Sbjct: 1216 --GNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYE-VGSV 1272
Query: 321 SSDSIDHSPAKKRVRTVCKCGAVTCRGYL 349
+ +C CGA+ CRG L
Sbjct: 1273 EGKEL-----------LCCCGAIECRGRL 1290
Score = 79.3 bits (194), Expect = 5e-15
Identities = 55/165 (33%), Positives = 78/165 (47%), Gaps = 25/165 (15%)
Query: 105 PPSDFYYINEYKPAPGISLVNEATF--GCSCTD-CFFQKCCPAEAGVLLAY--------- 152
PP Y E P G+ + F GC C D C + C + A
Sbjct: 701 PPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQIN 760
Query: 153 -NKNQQIK-----IPPGTPIYECNSRCQCGPD-CPNRIVQKGTQYSLCIFRTSNGRGWGV 205
N Q K +P G +YECN RC+C P+ C NR+VQ G Q L +F+T N +GWG+
Sbjct: 761 PNSGYQYKRLEECLPTG--VYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQN-KGWGI 817
Query: 206 KTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDY 250
+ L I + SFV Y G+++T + A++ G G Y +LD+
Sbjct: 818 RCLDDIAKGSFVCIYAGKILTDDFADKEGL---EMGDEYFANLDH 859
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 80.9 bits (198), Expect = 2e-15
Identities = 48/158 (30%), Positives = 83/158 (52%), Gaps = 24/158 (15%)
Query: 195 FRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGI--TYLFDLDYES 252
F S+ WG+ + I V+EYVG+ I A+ R + Y+++GI +Y+F +D+++
Sbjct: 1788 FCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHDT 1847
Query: 253 DEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDY 312
+DA + GN + F+NHSC+PN + +++ +I ++S + IN EE+T+DY
Sbjct: 1848 ---IIDATKCGNFARFINHSCNPNCYAKVITVES----QKKIVIYSKQHINVNEEITYDY 1900
Query: 313 QMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN 350
+ + V+ C CG+ CRG LN
Sbjct: 1901 KF---------------PIEDVKIPCLCGSENCRGTLN 1923
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 79.7 bits (195), Expect = 4e-15
Identities = 50/152 (32%), Positives = 79/152 (51%), Gaps = 23/152 (15%)
Query: 201 RGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYD--NKGITYLFDLDYESDEFTVD 258
+G G+ +++ + V+EY+G +I +E A RR + Y+ N+GI Y+F ++ +E +D
Sbjct: 5407 QGLGLYAAKDLEKHTMVIEYIGTIIRNEVANRREKIYEEQNRGI-YMFRIN---NEHVID 5462
Query: 259 AARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSG 318
A G + ++NHSC PN V D D +I + S+R I GEELT+DYQ
Sbjct: 5463 ATLTGGPARYINHSCAPNCVAEVVTFDKED----KIIIISSRRIPKGEELTYDYQFDFED 5518
Query: 319 DISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN 350
D + + C CGA CR ++N
Sbjct: 5519 D-------------QHKIPCHCGAWNCRKWMN 5537
>gi|224177469 SET domain, bifurcated 1 isoform 2 [Homo sapiens]
Length = 1290
Score = 79.3 bits (194), Expect = 5e-15
Identities = 55/165 (33%), Positives = 78/165 (47%), Gaps = 25/165 (15%)
Query: 105 PPSDFYYINEYKPAPGISLVNEATF--GCSCTD-CFFQKCCPAEAGVLLAY--------- 152
PP Y E P G+ + F GC C D C + C + A
Sbjct: 701 PPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQIN 760
Query: 153 -NKNQQIK-----IPPGTPIYECNSRCQCGPD-CPNRIVQKGTQYSLCIFRTSNGRGWGV 205
N Q K +P G +YECN RC+C P+ C NR+VQ G Q L +F+T N +GWG+
Sbjct: 761 PNSGYQYKRLEECLPTG--VYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQN-KGWGI 817
Query: 206 KTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDY 250
+ L I + SFV Y G+++T + A++ G G Y +LD+
Sbjct: 818 RCLDDIAKGSFVCIYAGKILTDDFADKEGL---EMGDEYFANLDH 859
Score = 76.6 bits (187), Expect = 3e-14
Identities = 50/149 (33%), Positives = 73/149 (48%), Gaps = 24/149 (16%)
Query: 201 RGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAA 260
RG+ +K+ I S M V + ++ + QFYD + Y+ D E
Sbjct: 1165 RGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQFYDGEESCYIIDAKLE--------- 1215
Query: 261 RYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDI 320
GN+ ++NHSC PNL V NVF+D D R P +A F+++ I AG ELT+DY + G +
Sbjct: 1216 --GNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASK-IRAGTELTWDYNYE-VGSV 1271
Query: 321 SSDSIDHSPAKKRVRTVCKCGAVTCRGYL 349
+ +C CGA+ CRG L
Sbjct: 1272 EGKEL-----------LCCCGAIECRGRL 1289
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 75.1 bits (183), Expect = 9e-14
Identities = 47/152 (30%), Positives = 79/152 (51%), Gaps = 23/152 (15%)
Query: 201 RGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYD--NKGITYLFDLDYESDEFTVD 258
+G G+ I++ + V+EY+G +I +E A R+ + Y+ N+G+ Y+F +D ++ +D
Sbjct: 4781 QGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGV-YMFRMD---NDHVID 4836
Query: 259 AARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSG 318
A G + ++NHSC PN V + R +I + S+R I GEEL +DY+
Sbjct: 4837 ATLTGGPARYINHSCAPNCVAEVVTFE----RGHKIIISSSRRIQKGEELCYDYKFDFED 4892
Query: 319 DISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN 350
D + + C CGAV CR ++N
Sbjct: 4893 D-------------QHKIPCHCGAVNCRKWMN 4911
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 73.9 bits (180), Expect = 2e-13
Identities = 47/158 (29%), Positives = 77/158 (48%), Gaps = 24/158 (15%)
Query: 195 FRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGI--TYLFDLDYES 252
F S WG+ + I V+EYVG+ I A+ R + Y +GI +YLF +D+++
Sbjct: 1572 FGRSRIHEWGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSYLFRVDHDT 1631
Query: 253 DEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDY 312
+DA + GN++ F+NH C PN + I++ +I ++S + I EE+T+DY
Sbjct: 1632 ---IIDATKCGNLARFINHCCTPNCYAKVITIES----QKKIVIYSKQPIGVDEEITYDY 1684
Query: 313 QMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN 350
+ + + C CG +CRG LN
Sbjct: 1685 KFPLEDN---------------KIPCLCGTESCRGSLN 1707
>gi|238624099 SET domain, bifurcated 2 isoform b [Homo sapiens]
Length = 707
Score = 66.2 bits (160), Expect = 4e-11
Identities = 35/92 (38%), Positives = 49/92 (53%), Gaps = 12/92 (13%)
Query: 255 FTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQM 314
F +DA + GNV F+NHSC PNL V NVF++ + P +A F+ R + A ELT+DY
Sbjct: 624 FLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGY 683
Query: 315 KGSGDISSDSIDHSPAKKRVRTVCKCGAVTCR 346
+ +G + I C+CG CR
Sbjct: 684 E-AGTVPEKEI-----------FCQCGVNKCR 703
Score = 58.9 bits (141), Expect = 6e-09
Identities = 33/80 (41%), Positives = 46/80 (57%), Gaps = 4/80 (5%)
Query: 154 KNQQIKIPPGTPIYECNSRCQCGPD-CPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIK 212
K Q +IP G IYEC+ C+C C NR+VQ G Q L +F+T +GWGV+ L I
Sbjct: 320 KRLQRQIPTG--IYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQ-KGWGVRCLDDID 376
Query: 213 RMSFVMEYVGEVITSEEAER 232
R +FV Y G +++ E+
Sbjct: 377 RGTFVCIYSGRLLSRANTEK 396
>gi|238624095 SET domain, bifurcated 2 isoform a [Homo sapiens]
Length = 719
Score = 66.2 bits (160), Expect = 4e-11
Identities = 35/92 (38%), Positives = 49/92 (53%), Gaps = 12/92 (13%)
Query: 255 FTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQM 314
F +DA + GNV F+NHSC PNL V NVF++ + P +A F+ R + A ELT+DY
Sbjct: 636 FLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGY 695
Query: 315 KGSGDISSDSIDHSPAKKRVRTVCKCGAVTCR 346
+ +G + I C+CG CR
Sbjct: 696 E-AGTVPEKEI-----------FCQCGVNKCR 715
Score = 58.9 bits (141), Expect = 6e-09
Identities = 33/80 (41%), Positives = 46/80 (57%), Gaps = 4/80 (5%)
Query: 154 KNQQIKIPPGTPIYECNSRCQCGPD-CPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIK 212
K Q +IP G IYEC+ C+C C NR+VQ G Q L +F+T +GWGV+ L I
Sbjct: 332 KRLQRQIPTG--IYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQ-KGWGVRCLDDID 388
Query: 213 RMSFVMEYVGEVITSEEAER 232
R +FV Y G +++ E+
Sbjct: 389 RGTFVCIYSGRLLSRANTEK 408
>gi|45356743 SET domain-containing 8 [Homo sapiens]
Length = 352
Score = 63.5 bits (153), Expect = 3e-10
Identities = 47/134 (35%), Positives = 67/134 (50%), Gaps = 12/134 (8%)
Query: 199 NGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGIT--YLFDLDYESDEFT 256
+G+G GV + R FV+EY G++I +A++R Y T Y++ Y S +
Sbjct: 224 DGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYC 283
Query: 257 VDAARYGN-VSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMK 315
VDA R N + +NHS N Q ID +P + L ++R I AGEEL +DY
Sbjct: 284 VDATRETNRLGRLINHSKCGNCQTKLHDIDG----VPHLILIASRDIAAGEELLYDY--- 336
Query: 316 GSGDISSDSIDHSP 329
GD S SI+ P
Sbjct: 337 --GDRSKASIEAHP 348
>gi|122937492 SET domain containing 5 [Homo sapiens]
Length = 1442
Score = 50.4 bits (119), Expect = 2e-06
Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 6/101 (5%)
Query: 215 SFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCD 274
+ ++EY G+V+ ++ E G F+ LF + E VDA +GN + F+ SC
Sbjct: 296 TLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCT 355
Query: 275 PNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELT--FDYQ 313
PN +V ++ D + + +++ I E+T FDY+
Sbjct: 356 PNAEVRHMIADG----MIHLCIYAVSAITKDAEVTIAFDYE 392
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,045,491
Number of Sequences: 37866
Number of extensions: 627408
Number of successful extensions: 1466
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1297
Number of HSP's gapped (non-prelim): 88
length of query: 350
length of database: 18,247,518
effective HSP length: 103
effective length of query: 247
effective length of database: 14,347,320
effective search space: 3543788040
effective search space used: 3543788040
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.