Guide to the Human Genome
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Name: SETD8 Sequence: fasta or formatted (352aa) NCBI GI: 45356743
Description:

SET domain-containing 8

Referenced in:

Histones, Related Proteins, and Modifying Enzymes

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            10.2         36           7
 C cysteine            2.0          7           1
 D aspartate           4.8         17           1
 E glutamate           7.7         27           2
 F phenylalanine       2.0          7           1
 G glycine             7.4         26           1
 H histidine           2.3          8           2
 I isoleucine          5.1         18           1
 K lysine             10.5         37           2
 L leucine             5.4         19           2
 M methionine          2.3          8           1
 N asparagine          3.1         11           1
 P proline             6.0         21           2
 Q glutamine           4.3         15           2
 R arginine            8.0         28           2
 S serine              6.8         24           2
 T threonine           4.3         15           1
 V valine              4.0         14           2
 W tryptophan          0.3          1           1
 Y tyrosine            3.7         13           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SET domain-containing 8 
MLL                   0.077   myeloid/lymphoid or mixed-lineage leukemia protein [...
MLL4                  0.066   myeloid/lymphoid or mixed-lineage leukemia 4 
SUV39H1               0.061   suppressor of variegation 3-9 homolog 1 
MLL2                  0.058   myeloid/lymphoid or mixed-lineage leukemia 2 
EZH1                  0.058   enhancer of zeste homolog 1 
EZH2                  0.057   enhancer of zeste 2 isoform b 
EZH2                  0.057   enhancer of zeste 2 isoform a 
SUV39H2               0.057   suppressor of variegation 3-9 homolog 2 
SETD2                 0.054   SET domain containing 2 
WHSC1                 0.051   Wolf-Hirschhorn syndrome candidate 1 protein isoform...
WHSC1                 0.051   Wolf-Hirschhorn syndrome candidate 1 protein isoform...
WHSC1                 0.051   Wolf-Hirschhorn syndrome candidate 1 protein isoform...
WHSC1                 0.051   Wolf-Hirschhorn syndrome candidate 1 protein isofor...
MLL3                  0.048   myeloid/lymphoid or mixed-lineage leukemia 3 
EHMT2                 0.048   euchromatic histone-lysine N-methyltransferase 2 is...
EHMT2                 0.048   euchromatic histone-lysine N-methyltransferase 2 is...
ASH1L                 0.044   absent, small, or homeotic 1-like 
SETD1A                0.042   SET domain containing 1A 
NSD1                  0.041   nuclear receptor binding SET domain protein 1 isofor...
NSD1                  0.041   nuclear receptor binding SET domain protein 1 isofor...
SETD1B                0.039   SET domain containing 1B 
WHSC1L1               0.039   WHSC1L1 protein isoform long 
EHMT1                 0.036   euchromatic histone-lysine N-methyltransferase 1 is...
SETMAR                0.036   SET domain and mariner transposase fusion 
BRD4                  0.020   bromodomain-containing protein 4 isoform short 
BRD4                  0.020   bromodomain-containing protein 4 isoform long 
KDM2B                 0.020   F-box and leucine-rich repeat protein 10 isoform a [...
C10orf12              0.017   hypothetical protein LOC26148 
SFRS11                0.017   splicing factor, arginine/serine-rich 11 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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