Guide to the Human Genome
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Search of human proteins with 13273317

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13273317 homeobox B8 [Homo sapiens]
         (243 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13273317 homeobox B8 [Homo sapiens]                                508   e-144
gi|12056969 homeobox C8 [Homo sapiens]                                295   3e-80
gi|15029506 homeobox D8 [Homo sapiens]                                265   3e-71
gi|85068580 homeobox B7 [Homo sapiens]                                143   2e-34
gi|24497556 homeobox A7 [Homo sapiens]                                141   4e-34
gi|23503237 homeobox B6 [Homo sapiens]                                125   3e-29
gi|4504469 homeobox B5 [Homo sapiens]                                 120   8e-28
gi|13489077 homeobox A6 [Homo sapiens]                                117   1e-26
gi|24497544 homeobox C6 isoform 2 [Homo sapiens]                      115   3e-26
gi|4758554 homeobox C6 isoform 1 [Homo sapiens]                       115   3e-26
gi|24497517 homeobox A5 [Homo sapiens]                                115   3e-26
gi|24497538 homeobox C4 [Homo sapiens]                                110   8e-25
gi|24497540 homeobox C4 [Homo sapiens]                                110   8e-25
gi|11321638 homeobox C5 [Homo sapiens]                                106   2e-23
gi|23397672 homeobox D4 [Homo sapiens]                                100   9e-22
gi|13273315 homeobox B4 [Homo sapiens]                                100   9e-22
gi|148613882 homeobox A4 [Homo sapiens]                                97   1e-20
gi|15029508 homeobox B9 [Homo sapiens]                                 97   1e-20
gi|23510366 homeobox D10 [Homo sapiens]                                96   4e-20
gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]           94   1e-19
gi|24497533 homeobox C10 [Homo sapiens]                                94   1e-19
gi|194363768 homeobox D9 [Homo sapiens]                                93   2e-19
gi|24497547 homeobox C9 [Homo sapiens]                                 92   3e-19
gi|182765442 homeobox A10 isoform a [Homo sapiens]                     91   1e-18
gi|24497551 homeobox A10 isoform b [Homo sapiens]                      90   2e-18
gi|23097236 homeobox A9 [Homo sapiens]                                 89   5e-18
gi|10140847 homeobox A2 [Homo sapiens]                                 85   5e-17
gi|24497513 homeobox A3 isoform a [Homo sapiens]                       84   9e-17
gi|13562112 homeobox A3 isoform a [Homo sapiens]                       84   9e-17
gi|84570137 homeobox B3 [Homo sapiens]                                 83   2e-16

>gi|13273317 homeobox B8 [Homo sapiens]
          Length = 243

 Score =  508 bits (1309), Expect = e-144
 Identities = 243/243 (100%), Positives = 243/243 (100%)

Query: 1   MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHG 60
           MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHG
Sbjct: 1   MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHG 60

Query: 61  PSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGE 120
           PSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGE
Sbjct: 61  PSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGE 120

Query: 121 EAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVS 180
           EAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVS
Sbjct: 121 EAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVS 180

Query: 181 HALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADEGDAQKG 240
           HALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADEGDAQKG
Sbjct: 181 HALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADEGDAQKG 240

Query: 241 DKK 243
           DKK
Sbjct: 241 DKK 243


>gi|12056969 homeobox C8 [Homo sapiens]
          Length = 242

 Score =  295 bits (754), Expect = 3e-80
 Identities = 150/243 (61%), Positives = 180/243 (74%), Gaps = 6/243 (2%)

Query: 1   MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPS-SGGSFQHPSQ-IQEFY 58
           MSSYFVN LFSKYK GESL P YYDC F Q +G    +VYGP  S   FQH S  +Q+F+
Sbjct: 1   MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGPGGSAPGFQHASHHVQDFF 60

Query: 59  H-GPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQ-DPDLVQYADCKLAAAS 116
           H G S +S + YQQNPC+++CHGD   FYGY+ L RQSL+GAQ +  +VQY DCK +A +
Sbjct: 61  HHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANT 120

Query: 117 GLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRR 176
              E      Q+ SP+ +FPWMRP A  GRR GRQTYSRYQTLELEKEFLFNPYLTRKRR
Sbjct: 121 NSSEGQGHLNQNSSPSLMFPWMRPHAP-GRRSGRQTYSRYQTLELEKEFLFNPYLTRKRR 179

Query: 177 IEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADEGD 236
           IEVSHALGLTERQVKIWFQNRRMKWKKENNKDK P ++ ++E++E++  E   +  +E +
Sbjct: 180 IEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGAR-DEEKVEEEGNEEEEKEEEEKE 238

Query: 237 AQK 239
             K
Sbjct: 239 ENK 241


>gi|15029506 homeobox D8 [Homo sapiens]
          Length = 290

 Score =  265 bits (677), Expect = 3e-71
 Identities = 147/276 (53%), Positives = 176/276 (63%), Gaps = 53/276 (19%)

Query: 1   MSSYFVNSLFSKYKT--------GESLRPNYYDCGFAQDLGGRPTV------VYGPSSGG 46
           MSSYFVN L+SKYK         GE++ P YYDC FA ++GGR         +YG S+ G
Sbjct: 1   MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG 60

Query: 47  ---------SFQHPS-------------QIQEFYHGPSSLSTAPYQQNP----------- 73
                    +  HPS             + QE++H       A YQ  P           
Sbjct: 61  FPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPP 120

Query: 74  ---CA-VACHGDPGNFYGYDPLQRQSLFGAQ-DPDLVQYADCKLAAASGLGEEAEGSEQS 128
              C  +ACHG+P  FYGYD LQRQ +F  Q + +LVQY DCK +++  +GE+ +   QS
Sbjct: 121 PPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCK-SSSGNIGEDPDHLNQS 179

Query: 129 PSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTER 188
            SP+Q+FPWMRPQAA GRRRGRQTYSR+QTLELEKEFLFNPYLTRKRRIEVSHAL LTER
Sbjct: 180 SSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTER 239

Query: 189 QVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQK 224
           QVKIWFQNRRMKWKKENNKDKFP S+ E ++ E +K
Sbjct: 240 QVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKK 275


>gi|85068580 homeobox B7 [Homo sapiens]
          Length = 217

 Score =  143 bits (360), Expect = 2e-34
 Identities = 92/230 (40%), Positives = 126/230 (54%), Gaps = 20/230 (8%)

Query: 2   SSYFVNSLFSKYKTGESLR-----PNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQE 56
           S Y+ N+LFSKY    S+      P    C FA +   RP   YG  SG SF   + +Q 
Sbjct: 3   SLYYANTLFSKYPASSSVFATGAFPEQTSCAFASN-PQRPG--YGAGSGASFA--ASMQG 57

Query: 57  FYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAAS 116
            Y G   ++     Q+   V   G     YG +P          + +L        A A+
Sbjct: 58  LYPGGGGMAG----QSAAGVYAAG-----YGLEPSSFNMHCAPFEQNLSGVCPGDSAKAA 108

Query: 117 GLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRR 176
           G  E+ +    + S  +++PWMR  +   R+RGRQTY+RYQTLELEKEF +N YLTR+RR
Sbjct: 109 GAKEQRDSDLAAESNFRIYPWMR-SSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRR 167

Query: 177 IEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLE 226
           IE++H L LTERQ+KIWFQNRRMKWKKEN      ++  ++ E E+++ E
Sbjct: 168 IEIAHTLCLTERQIKIWFQNRRMKWKKENKTAGPGTTGQDRAEAEEEEEE 217


>gi|24497556 homeobox A7 [Homo sapiens]
          Length = 230

 Score =  141 bits (356), Expect = 4e-34
 Identities = 99/246 (40%), Positives = 132/246 (53%), Gaps = 28/246 (11%)

Query: 2   SSYFVNSLFSKYKTGESLRPNYY--DCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYH 59
           SSY+VN+LFSKY  G SL  N     C FA +        YG  +G      S +   Y+
Sbjct: 3   SSYYVNALFSKYTAGASLFQNAEPTSCSFAPN---SQRSGYGAGAGA---FASTVPGLYN 56

Query: 60  GPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLG 119
             S L  +P+         +G   + YG  P    + +    P L     C   A     
Sbjct: 57  VNSPLYQSPFASG------YGLGADAYGNLPC---ASYDQNIPGL-----CSDLAKGACD 102

Query: 120 EEAEGSEQSPSPT--QLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRI 177
           +  EG+    +    +++PWMR  +   R+RGRQTY+RYQTLELEKEF FN YLTR+RRI
Sbjct: 103 KTDEGALHGAAEANFRIYPWMR-SSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRI 161

Query: 178 EVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADEGDA 237
           E++HAL LTERQ+KIWFQNRRMKWKKE +KD+ P++    E         A  AAD+ D 
Sbjct: 162 EIAHALCLTERQIKIWFQNRRMKWKKE-HKDEGPTAAAAPEGAVPS--AAATAAADKADE 218

Query: 238 QKGDKK 243
           +  D++
Sbjct: 219 EDDDEE 224


>gi|23503237 homeobox B6 [Homo sapiens]
          Length = 224

 Score =  125 bits (314), Expect = 3e-29
 Identities = 94/234 (40%), Positives = 117/234 (50%), Gaps = 23/234 (9%)

Query: 1   MSSYFVNSLFS-KYKTGESL---RPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQE 56
           MSSYFVNS F     +G+     +   Y  G+A  L   P   YGP  G   Q       
Sbjct: 1   MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAP-YGPGPG---QDKGFATS 56

Query: 57  FYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAAS 116
            Y+ P+      Y +   A  C   P   +  +     +L GA +         K   A 
Sbjct: 57  SYYPPAG---GGYGR---AAPCDYGPAPAFYREKESACALSGADEQPPFHPEPRKSDCAQ 110

Query: 117 GLGEEAEGSEQSPSPTQLFPWMRPQAAAGR-------RRGRQTYSRYQTLELEKEFLFNP 169
                 E  EQ  S T ++PWM+   +          RRGRQTY+RYQTLELEKEF +N 
Sbjct: 111 DKSVFGETEEQKCS-TPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNR 169

Query: 170 YLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQ 223
           YLTR+RRIE++HAL LTERQ+KIWFQNRRMKWKKE+          E+EE EKQ
Sbjct: 170 YLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEE-EKQ 222


>gi|4504469 homeobox B5 [Homo sapiens]
          Length = 269

 Score =  120 bits (302), Expect = 8e-28
 Identities = 90/259 (34%), Positives = 113/259 (43%), Gaps = 60/259 (23%)

Query: 1   MSSYFVNSLFSKYKTGESLRPNYYDCGFA-----QDLGGRPTVVYGPSSGG--------- 46
           MSSYFVNS   +Y  G   +   Y  G +     +D     T  YG +  G         
Sbjct: 1   MSSYFVNSFSGRYPNGPDYQLLNYGSGSSLSGSYRDPAAMHTGSYGYNYNGMDLSVNRSS 60

Query: 47  --------------SFQHPSQIQEFYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDP-L 91
                         +F  P+Q   F    SS S +  +  PC        G+ +G  P  
Sbjct: 61  ASSSHFGAVGESSRAFPAPAQEPRFRQAASSCSLSSPESLPCT------NGDSHGAKPSA 114

Query: 92  QRQSLFGAQDPDLVQYADCKLAAASGLGEEAEGSEQSPS-------------------PT 132
              S           + +   A+AS   EEA     SPS                     
Sbjct: 115 SSPSDQATSASSSANFTEIDEASASSEPEEAASQLSSPSLARAQPEPMATSTAAPEGQTP 174

Query: 133 QLFPWMRP------QAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLT 186
           Q+FPWMR             +R R  Y+RYQTLELEKEF FN YLTR+RRIE++HAL L+
Sbjct: 175 QIFPWMRKLHISHDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLS 234

Query: 187 ERQVKIWFQNRRMKWKKEN 205
           ERQ+KIWFQNRRMKWKK+N
Sbjct: 235 ERQIKIWFQNRRMKWKKDN 253


>gi|13489077 homeobox A6 [Homo sapiens]
          Length = 233

 Score =  117 bits (292), Expect = 1e-26
 Identities = 95/232 (40%), Positives = 123/232 (53%), Gaps = 45/232 (19%)

Query: 1   MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHG 60
           MSSYFVN  F          P     G    LG  P    G  +   F  P+      +G
Sbjct: 1   MSSYFVNPTF----------PGSLPSGQDSFLGQLPLYQAGYDALRPF--PAS-----YG 43

Query: 61  PSSLS----TAP--YQQNPCAVACHG-----DPGNFYGYDPLQRQSLFGAQDP----DLV 105
            SSL     T+P  YQQ+   +AC+          FY    L   S  G+       D +
Sbjct: 44  ASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYL 103

Query: 106 QYA---DCKLAAASGLGEEA--EGSEQSPSPTQLFPWM-RPQAAAGR------RRGRQTY 153
            ++     K  ++SG G+    EG+++  + + ++PWM R  + AG       RRGRQTY
Sbjct: 104 HFSPEQQYKPDSSSGQGKALHDEGADRKYT-SPVYPWMQRMNSCAGAVYGSHGRRGRQTY 162

Query: 154 SRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKEN 205
           +RYQTLELEKEF FN YLTR+RRIE+++AL LTERQ+KIWFQNRRMKWKKEN
Sbjct: 163 TRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKEN 214


>gi|24497544 homeobox C6 isoform 2 [Homo sapiens]
          Length = 153

 Score =  115 bits (289), Expect = 3e-26
 Identities = 56/81 (69%), Positives = 66/81 (81%), Gaps = 7/81 (8%)

Query: 133 QLFPWMRPQAA-------AGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGL 185
           Q++PWM+   +       A RRRGRQ YSRYQTLELEKEF FN YLTR+RRIE+++AL L
Sbjct: 39  QIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCL 98

Query: 186 TERQVKIWFQNRRMKWKKENN 206
           TERQ+KIWFQNRRMKWKKE+N
Sbjct: 99  TERQIKIWFQNRRMKWKKESN 119


>gi|4758554 homeobox C6 isoform 1 [Homo sapiens]
          Length = 235

 Score =  115 bits (289), Expect = 3e-26
 Identities = 56/81 (69%), Positives = 66/81 (81%), Gaps = 7/81 (8%)

Query: 133 QLFPWMRPQAA-------AGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGL 185
           Q++PWM+   +       A RRRGRQ YSRYQTLELEKEF FN YLTR+RRIE+++AL L
Sbjct: 121 QIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCL 180

Query: 186 TERQVKIWFQNRRMKWKKENN 206
           TERQ+KIWFQNRRMKWKKE+N
Sbjct: 181 TERQIKIWFQNRRMKWKKESN 201


>gi|24497517 homeobox A5 [Homo sapiens]
          Length = 270

 Score =  115 bits (288), Expect = 3e-26
 Identities = 90/255 (35%), Positives = 114/255 (44%), Gaps = 51/255 (20%)

Query: 1   MSSYFVNSLFSKYKTGESLR-PNYYDCGFAQDL--------GGRPTVVY-------GPSS 44
           MSSYFVNS   +Y  G   +  NY D     +          GR    Y       G S 
Sbjct: 1   MSSYFVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSG 60

Query: 45  GGSFQHPSQIQEFYHGPSSLSTAPYQQNPCAVACH----------------GDPGNFYGY 88
            G F    + + +    S+    P    P A + H                G   +  G 
Sbjct: 61  SGHFGSGERARSYAASASAAPAEPRYSQP-ATSTHSPQPDPLPCSAVAPSPGSDSHHGGK 119

Query: 89  DPLQRQSLFGAQDPDLVQYADCKLAAASGLGEEAEGS--------EQSPSPT---QLFPW 137
           + L   S   A        +   +  ASG  E+A  S        E SP+P    Q++PW
Sbjct: 120 NSLSNSSGASADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYPW 179

Query: 138 MRPQ-------AAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQV 190
           MR              +R R  Y+RYQTLELEKEF FN YLTR+RRIE++HAL L+ERQ+
Sbjct: 180 MRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQI 239

Query: 191 KIWFQNRRMKWKKEN 205
           KIWFQNRRMKWKK+N
Sbjct: 240 KIWFQNRRMKWKKDN 254


>gi|24497538 homeobox C4 [Homo sapiens]
          Length = 264

 Score =  110 bits (276), Expect = 8e-25
 Identities = 82/233 (35%), Positives = 114/233 (48%), Gaps = 33/233 (14%)

Query: 1   MSSYFVNSLF--SKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFY 58
           MSSY ++S +   K+   E    N Y       +       YG +    FQH  Q  E Y
Sbjct: 3   MSSYLMDSNYIDPKFPPCEEYSQNSY-------IPEHSPEYYGRTRESGFQHHHQ--ELY 53

Query: 59  HGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGL 118
             P    + P +Q  C  +  G PGN  G+ P Q       +   L + A    A+AS  
Sbjct: 54  PPPPPRPSYPERQYSCT-SLQG-PGNSRGHGPAQAGHHHPEKSQSLCEPAPLSGASASPS 111

Query: 119 GEEAEGSEQSPSPTQ--------LFPWMR--------PQAAAGR-RRGRQTYSRYQTLEL 161
                 S+ +P            ++PWM+        P    G  +R R  Y+R Q LEL
Sbjct: 112 PAPPACSQPAPDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLEL 171

Query: 162 EKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSK 214
           EKEF +N YLTR+RRIE++H+L L+ERQ+KIWFQNRRMKWKK++   + P++K
Sbjct: 172 EKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDH---RLPNTK 221


>gi|24497540 homeobox C4 [Homo sapiens]
          Length = 264

 Score =  110 bits (276), Expect = 8e-25
 Identities = 82/233 (35%), Positives = 114/233 (48%), Gaps = 33/233 (14%)

Query: 1   MSSYFVNSLF--SKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFY 58
           MSSY ++S +   K+   E    N Y       +       YG +    FQH  Q  E Y
Sbjct: 3   MSSYLMDSNYIDPKFPPCEEYSQNSY-------IPEHSPEYYGRTRESGFQHHHQ--ELY 53

Query: 59  HGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGL 118
             P    + P +Q  C  +  G PGN  G+ P Q       +   L + A    A+AS  
Sbjct: 54  PPPPPRPSYPERQYSCT-SLQG-PGNSRGHGPAQAGHHHPEKSQSLCEPAPLSGASASPS 111

Query: 119 GEEAEGSEQSPSPTQ--------LFPWMR--------PQAAAGR-RRGRQTYSRYQTLEL 161
                 S+ +P            ++PWM+        P    G  +R R  Y+R Q LEL
Sbjct: 112 PAPPACSQPAPDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLEL 171

Query: 162 EKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSK 214
           EKEF +N YLTR+RRIE++H+L L+ERQ+KIWFQNRRMKWKK++   + P++K
Sbjct: 172 EKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDH---RLPNTK 221


>gi|11321638 homeobox C5 [Homo sapiens]
          Length = 222

 Score =  106 bits (265), Expect = 2e-23
 Identities = 50/85 (58%), Positives = 64/85 (75%), Gaps = 3/85 (3%)

Query: 124 GSEQSPSPTQLFPWMRPQAAAGR---RRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVS 180
           G  Q P+P Q++PWM     +     +R R +Y+RYQTLELEKEF FN YLTR+RRIE++
Sbjct: 130 GLSQPPAPPQIYPWMTKLHMSHETDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIA 189

Query: 181 HALGLTERQVKIWFQNRRMKWKKEN 205
           + L L ERQ+KIWFQNRRMKWKK++
Sbjct: 190 NNLCLNERQIKIWFQNRRMKWKKDS 214


>gi|23397672 homeobox D4 [Homo sapiens]
          Length = 255

 Score =  100 bits (250), Expect = 9e-22
 Identities = 76/225 (33%), Positives = 103/225 (45%), Gaps = 19/225 (8%)

Query: 1   MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHG 60
           MSSY VNS +   K        Y   G+  + G       G + G  FQ P        G
Sbjct: 3   MSSYMVNSKYVDPKFPPC--EEYLQGGYLGEQGA--DYYGGGAQGADFQPPGLYPRPDFG 58

Query: 61  PSSLS-TAPYQQNPCAVACHG-DPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGL 118
                 + P   +      HG +PG   G+     +       P        +  + S  
Sbjct: 59  EQPFGGSGPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPPAPPPAPLPGARAYSQSDP 118

Query: 119 GEEAEGSEQSPSPTQLFPWMR--------PQAAAGR-RRGRQTYSRYQTLELEKEFLFNP 169
            +   G+     P  ++PWM+        P    G  +R R  Y+R Q LELEKEF FN 
Sbjct: 119 KQPPSGTALK-QPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNR 177

Query: 170 YLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSK 214
           YLTR+RRIE++H L L+ERQ+KIWFQNRRMKWKK++   K P++K
Sbjct: 178 YLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDH---KLPNTK 219


>gi|13273315 homeobox B4 [Homo sapiens]
          Length = 251

 Score =  100 bits (250), Expect = 9e-22
 Identities = 53/102 (51%), Positives = 69/102 (67%), Gaps = 19/102 (18%)

Query: 129 PSPTQ-------LFPWMR--------PQAAAGR-RRGRQTYSRYQTLELEKEFLFNPYLT 172
           PSP+        ++PWMR        P  A G  +R R  Y+R Q LELEKEF +N YLT
Sbjct: 129 PSPSHSACKEPVVYPWMRKVHVSTVNPNYAGGEPKRSRTAYTRQQVLELEKEFHYNRYLT 188

Query: 173 RKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSK 214
           R+RR+E++HAL L+ERQ+KIWFQNRRMKWKK++   K P++K
Sbjct: 189 RRRRVEIAHALCLSERQIKIWFQNRRMKWKKDH---KLPNTK 227


>gi|148613882 homeobox A4 [Homo sapiens]
          Length = 320

 Score = 97.4 bits (241), Expect = 1e-20
 Identities = 50/90 (55%), Positives = 63/90 (70%), Gaps = 12/90 (13%)

Query: 134 LFPWMR--------PQAAAGR-RRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALG 184
           ++PWM+        P    G  +R R  Y+R Q LELEKEF FN YLTR+RRIE++H L 
Sbjct: 194 VYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLC 253

Query: 185 LTERQVKIWFQNRRMKWKKENNKDKFPSSK 214
           L+ERQVKIWFQNRRMKWKK++   K P++K
Sbjct: 254 LSERQVKIWFQNRRMKWKKDH---KLPNTK 280


>gi|15029508 homeobox B9 [Homo sapiens]
          Length = 250

 Score = 97.1 bits (240), Expect = 1e-20
 Identities = 82/241 (34%), Positives = 113/241 (46%), Gaps = 35/241 (14%)

Query: 1   MSSYFVNSLFS---------KYKTGE---SLRPNYYDCGFAQDLGGRPTV-VYGPSSGGS 47
           +SSY+V+S+ S         K+ +G+   S +P + +         +P   V+G S    
Sbjct: 7   LSSYYVDSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGASWAPL 66

Query: 48  FQHPS-QIQEFYHG---PSSLSTAP--YQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQD 101
             H S  +   YH    P  +  A   Y +     A  G+     G   ++ + L GA  
Sbjct: 67  SPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEPLLGAPG 126

Query: 102 PDLVQYADCKLAAASGLGEEA---------------EGSEQSPSPTQLFPWMRPQAAAGR 146
            +L++    + +  +  G EA               EGSE    P Q  P      A   
Sbjct: 127 -ELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWLHARSS 185

Query: 147 RRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENN 206
           R+ R  Y++YQTLELEKEFLFN YLTR RR EV+  L L+ERQVKIWFQNRRMK KK N 
Sbjct: 186 RKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNK 245

Query: 207 K 207
           +
Sbjct: 246 E 246


>gi|23510366 homeobox D10 [Homo sapiens]
          Length = 340

 Score = 95.5 bits (236), Expect = 4e-20
 Identities = 62/170 (36%), Positives = 92/170 (54%), Gaps = 19/170 (11%)

Query: 55  QEFYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYAD----- 109
           QE+ + P   ST   Q NP   A           +    + + G Q+P  V   +     
Sbjct: 164 QEYNNSPEGSSTVMLQLNPRGAAKPQLSAAQLQMEKKMNEPVSG-QEPTKVSQVESPEAK 222

Query: 110 ----------CKLAAASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTL 159
                      +++ +S   +E E  E+  S T    W+   A +GR++ R  Y+++QTL
Sbjct: 223 GGLPEERSCLAEVSVSSPEVQEKESKEEIKSDTPTSNWLT--AKSGRKK-RCPYTKHQTL 279

Query: 160 ELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDK 209
           ELEKEFLFN YLTR+RR+E+S ++ LT+RQVKIWFQNRRMK KK + +++
Sbjct: 280 ELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRENR 329


>gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]
          Length = 283

 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 54/112 (48%), Positives = 68/112 (60%), Gaps = 21/112 (18%)

Query: 119 GEEAEGSE----QSPSPTQL-FPWMRPQAA-------AG---------RRRGRQTYSRYQ 157
           G   EG+E    + P+  QL FPWM+   A       AG          +R R  Y+R Q
Sbjct: 98  GPFPEGAEPGVLEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQ 157

Query: 158 TLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDK 209
            LELEKEFLFN Y++R RR+E++  L LTER +KIWFQNRRMKWKKE +K +
Sbjct: 158 LLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKKR 209


>gi|24497533 homeobox C10 [Homo sapiens]
          Length = 342

 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 54/117 (46%), Positives = 75/117 (64%), Gaps = 4/117 (3%)

Query: 94  QSLFGAQ-DPDLVQYADCKLAAASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQT 152
           QSL G +  P   +    K A +S    + E  E+  +      W+   A +GR++ R  
Sbjct: 218 QSLAGPKGSPSESEKERAKAADSSPDTSDNEAKEEIKAENTTGNWLT--AKSGRKK-RCP 274

Query: 153 YSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDK 209
           Y+++QTLELEKEFLFN YLTR+RR+E+S  + LT+RQVKIWFQNRRMK KK N +++
Sbjct: 275 YTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENR 331


>gi|194363768 homeobox D9 [Homo sapiens]
          Length = 352

 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 55/96 (57%), Positives = 62/96 (64%), Gaps = 6/96 (6%)

Query: 120 EEAEGSEQSPSPTQLFPWMRPQA----AAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKR 175
           +E E     P   QL P   P A    A   R+ R  Y++YQTLELEKEFLFN YLTR R
Sbjct: 256 KEEEKQHSQPQQQQLDP-NNPAANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDR 314

Query: 176 RIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFP 211
           R EV+  L LTERQVKIWFQNRRMK KK  +K+K P
Sbjct: 315 RYEVARILNLTERQVKIWFQNRRMKMKK-MSKEKCP 349


>gi|24497547 homeobox C9 [Homo sapiens]
          Length = 260

 Score = 92.4 bits (228), Expect = 3e-19
 Identities = 51/94 (54%), Positives = 62/94 (65%), Gaps = 4/94 (4%)

Query: 114 AASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTR 173
           A +G   + E ++  PS   +  W+    A   R+ R  Y++YQTLELEKEFLFN YLTR
Sbjct: 164 ALAGSKHKEEKADLDPS-NPVANWIH---ARSTRKKRCPYTKYQTLELEKEFLFNMYLTR 219

Query: 174 KRRIEVSHALGLTERQVKIWFQNRRMKWKKENNK 207
            RR EV+  L LTERQVKIWFQNRRMK KK N +
Sbjct: 220 DRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKE 253


>gi|182765442 homeobox A10 isoform a [Homo sapiens]
          Length = 410

 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 53/107 (49%), Positives = 71/107 (66%), Gaps = 12/107 (11%)

Query: 114 AASGLGEE-----AEGSEQSPSPTQLFPWMRPQAA------AGRRRGRQTYSRYQTLELE 162
           A+S   EE     +E S+ SP    L       AA      +GR++ R  Y+++QTLELE
Sbjct: 294 ASSSAAEELSPAPSESSKASPEKDSLGNSKGENAANWLTAKSGRKK-RCPYTKHQTLELE 352

Query: 163 KEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDK 209
           KEFLFN YLTR+RR+E+S ++ LT+RQVKIWFQNRRMK KK N +++
Sbjct: 353 KEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNRENR 399


>gi|24497551 homeobox A10 isoform b [Homo sapiens]
          Length = 94

 Score = 90.1 bits (222), Expect = 2e-18
 Identities = 43/68 (63%), Positives = 58/68 (85%), Gaps = 1/68 (1%)

Query: 142 AAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKW 201
           A +GR++ R  Y+++QTLELEKEFLFN YLTR+RR+E+S ++ LT+RQVKIWFQNRRMK 
Sbjct: 17  AKSGRKK-RCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKL 75

Query: 202 KKENNKDK 209
           KK N +++
Sbjct: 76  KKMNRENR 83


>gi|23097236 homeobox A9 [Homo sapiens]
          Length = 272

 Score = 88.6 bits (218), Expect = 5e-18
 Identities = 46/67 (68%), Positives = 52/67 (77%), Gaps = 1/67 (1%)

Query: 143 AAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWK 202
           A   R+ R  Y+++QTLELEKEFLFN YLTR RR EV+  L LTERQVKIWFQNRRMK K
Sbjct: 203 ARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMK 262

Query: 203 KENNKDK 209
           K  NKD+
Sbjct: 263 K-INKDR 268


>gi|10140847 homeobox A2 [Homo sapiens]
          Length = 376

 Score = 85.1 bits (209), Expect = 5e-17
 Identities = 50/98 (51%), Positives = 59/98 (60%), Gaps = 11/98 (11%)

Query: 142 AAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKW 201
           +  G RR R  Y+  Q LELEKEF FN YL R RR+E++  L LTERQVK+WFQNRRMK 
Sbjct: 139 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH 198

Query: 202 K-----KENN------KDKFPSSKCEQEELEKQKLERA 228
           K     KEN       K    S K E++E EK   E+A
Sbjct: 199 KRQTQCKENQNSEGKCKSLEDSEKVEEDEEEKTLFEQA 236


>gi|24497513 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score = 84.3 bits (207), Expect = 9e-17
 Identities = 46/102 (45%), Positives = 58/102 (56%), Gaps = 27/102 (26%)

Query: 130 SPT---QLFPWMR------------------------PQAAAGRRRGRQTYSRYQTLELE 162
           SPT   Q+FPWM+                        P   A  +R R  Y+  Q +ELE
Sbjct: 148 SPTVAKQIFPWMKESRQNTKQKTSSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELE 207

Query: 163 KEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKE 204
           KEF FN YL R RR+E+++ L LTERQ+KIWFQNRRMK+KK+
Sbjct: 208 KEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKD 249


>gi|13562112 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score = 84.3 bits (207), Expect = 9e-17
 Identities = 46/102 (45%), Positives = 58/102 (56%), Gaps = 27/102 (26%)

Query: 130 SPT---QLFPWMR------------------------PQAAAGRRRGRQTYSRYQTLELE 162
           SPT   Q+FPWM+                        P   A  +R R  Y+  Q +ELE
Sbjct: 148 SPTVAKQIFPWMKESRQNTKQKTSSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELE 207

Query: 163 KEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKE 204
           KEF FN YL R RR+E+++ L LTERQ+KIWFQNRRMK+KK+
Sbjct: 208 KEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKD 249


>gi|84570137 homeobox B3 [Homo sapiens]
          Length = 431

 Score = 82.8 bits (203), Expect = 2e-16
 Identities = 39/74 (52%), Positives = 51/74 (68%)

Query: 140 PQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRM 199
           P  +A  +R R  Y+  Q +ELEKEF FN YL R RR+E+++ L L+ERQ+KIWFQNRRM
Sbjct: 182 PPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRM 241

Query: 200 KWKKENNKDKFPSS 213
           K+KK+       SS
Sbjct: 242 KYKKDQKAKGLASS 255


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,108,591
Number of Sequences: 37866
Number of extensions: 559811
Number of successful extensions: 2398
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 291
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 1986
Number of HSP's gapped (non-prelim): 438
length of query: 243
length of database: 18,247,518
effective HSP length: 99
effective length of query: 144
effective length of database: 14,498,784
effective search space: 2087824896
effective search space used: 2087824896
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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