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Search of human proteins with 48255891
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo
sapiens]
(525 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap... 1088 0.0
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap... 1069 0.0
gi|221219020 NYD-SP11 protein [Homo sapiens] 72 1e-12
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 69 8e-12
gi|4505257 moesin [Homo sapiens] 64 3e-10
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 64 4e-10
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 64 4e-10
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 63 8e-10
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 62 2e-09
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 60 4e-09
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 60 4e-09
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 60 5e-09
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 60 6e-09
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 59 8e-09
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 59 8e-09
gi|148746195 trichohyalin [Homo sapiens] 59 1e-08
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 58 2e-08
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 58 2e-08
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 57 3e-08
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 57 4e-08
gi|4506467 radixin [Homo sapiens] 57 5e-08
gi|14249738 N-acetylglucosamine-1-phosphotransferase, gamma subu... 57 5e-08
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 56 9e-08
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 56 9e-08
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 55 1e-07
gi|17975763 myelin transcription factor 1 [Homo sapiens] 55 1e-07
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 55 2e-07
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 55 2e-07
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens] 55 2e-07
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 55 2e-07
>gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo
sapiens]
Length = 525
Score = 1088 bits (2814), Expect = 0.0
Identities = 525/525 (100%), Positives = 525/525 (100%)
Query: 1 MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKD 60
MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKD
Sbjct: 1 MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKD 60
Query: 61 GSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG 120
GSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG
Sbjct: 61 GSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG 120
Query: 121 RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK 180
RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK
Sbjct: 121 RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK 180
Query: 181 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL 240
EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL
Sbjct: 181 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL 240
Query: 241 DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP 300
DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP
Sbjct: 241 DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP 300
Query: 301 KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQT 360
KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQT
Sbjct: 301 KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQT 360
Query: 361 QAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTTNEY 420
QAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTTNEY
Sbjct: 361 QAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTTNEY 420
Query: 421 VYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTTVRL 480
VYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTTVRL
Sbjct: 421 VYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTTVRL 480
Query: 481 LCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL 525
LCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL
Sbjct: 481 LCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL 525
>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
sapiens]
Length = 528
Score = 1069 bits (2765), Expect = 0.0
Identities = 519/528 (98%), Positives = 520/528 (98%), Gaps = 3/528 (0%)
Query: 1 MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKD 60
MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKD
Sbjct: 1 MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKD 60
Query: 61 GSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG 120
GSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG
Sbjct: 61 GSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG 120
Query: 121 RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK 180
RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK
Sbjct: 121 RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK 180
Query: 181 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL 240
EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL
Sbjct: 181 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL 240
Query: 241 DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP 300
DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP
Sbjct: 241 DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP 300
Query: 301 KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQG---EQPKPASPAEEDKMPPYD 357
KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSE P+PASPAEEDKMPPYD
Sbjct: 301 KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYD 360
Query: 358 EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTT 417
EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTT
Sbjct: 361 EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTT 420
Query: 418 NEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTT 477
NEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTT
Sbjct: 421 NEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTT 480
Query: 478 VRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL 525
VRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL
Sbjct: 481 VRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL 528
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 72.0 bits (175), Expect = 1e-12
Identities = 75/295 (25%), Positives = 139/295 (47%), Gaps = 34/295 (11%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQ--KKLIELQAGKKSLEDQVE 174
++ + R+ +++ +++E +L KIL K R+E++ ++ I++ K++L +
Sbjct: 2050 RKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKER 2109
Query: 175 MLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTEL 234
L + + + E + E+ +L +++ A+ Q++ LA + ++ + T ++L
Sbjct: 2110 RLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRK--LANKMRRMINKEEKMTEEESKL 2167
Query: 235 -QTHPE--LDTDGDGALSEAEAQALLS-----------GDTQTDATSFYDRVWAAIRDKY 280
+ H E LD + +G + E E L GD + F +V +++
Sbjct: 2168 ARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKE--KFSSQVDEVESEEH 2225
Query: 281 RSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGE 340
SE + + L + E+Q + S EE EEEEE EEEE EEEEE E +GE
Sbjct: 2226 FSEEMES---------LLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGE 2276
Query: 341 QPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDME-ESIRNLEQE 394
+ K EE+K E+ + + QE FEE E + + E ES+ + E+E
Sbjct: 2277 E-KQVEKEEEEKKKKKKEKKK---EEVQEKEEVFEEKEEIMSEEETESLSDEEEE 2327
Score = 44.7 bits (104), Expect = 2e-04
Identities = 58/291 (19%), Positives = 128/291 (43%), Gaps = 42/291 (14%)
Query: 122 KERESLQQMAEVTREGFRLKKILIEDWKKARE--EKQKKLIELQAGKKSLEDQVEMLRTV 179
KE + ++ +E+T++ +L + + K R K++K+ E ++ K E++
Sbjct: 2121 KEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEES--KLARKHSEVILDD 2178
Query: 180 KEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPE 239
+EE E E ++ W ++ A + + +E + V E+++
Sbjct: 2179 EEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSS-------------QVDEVESEEH 2225
Query: 240 LDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTE 299
+ + L E E Q LS + + + +R +R++ E
Sbjct: 2226 FSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEE-----------------E 2268
Query: 300 PKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQ 359
KEE+ +EEEE++++++E+ +EE +E++ EV E+ + S E + + +E+
Sbjct: 2269 RKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKE-EVFEEKEEIMSEEETESLSDEEEE 2327
Query: 360 TQAF-----IDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFG-PNGE 404
++ +D +E K E+ + + +S+R E+ +S G P+G+
Sbjct: 2328 EESCSLEEEVDREKEILKK-EKQFKLQEQRRKSLRGRERVLSILRGVPHGK 2377
Score = 44.3 bits (103), Expect = 3e-04
Identities = 60/290 (20%), Positives = 114/290 (39%), Gaps = 48/290 (16%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
KE+ K+ E + EV+REG EEK++++ E Q + ++++ +
Sbjct: 1534 KEQQYKDEEEVTLEEEVSREG---------------EEKEQQVTEEQ---RHIQEEHKWA 1575
Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAK----AQQEQELAADAFKELDDDMDGTVSVT 232
R ++ A ++ A+E+ + EE+ A + AQ+E++LA K DD +
Sbjct: 1576 RIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDRE------ 1629
Query: 233 ELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAP 292
+G ++ E G+ + + + K+ A + A
Sbjct: 1630 --------MAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAK 1681
Query: 293 SAPDLTEPKE------EQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPAS 346
L E K E+ P + +E+E +E EE E + EE + + +
Sbjct: 1682 KGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGK 1741
Query: 347 PAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEIS 396
EE K +E+ A+ R K E E L EE + +++++
Sbjct: 1742 LVEEKKKLAEEEEALAW------QREKLSEEETKLAQEEELLIQEKEKLA 1785
Score = 41.2 bits (95), Expect = 0.002
Identities = 67/302 (22%), Positives = 123/302 (40%), Gaps = 61/302 (20%)
Query: 133 VTREGFRLKKILIED----WKKARE-----------EKQKKLIELQAGKKSLEDQVEMLR 177
VT+E R K+++ + KKAR+ +K KK+I L+ G ++ ++
Sbjct: 1332 VTQEVIRHKEVMPREEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEIS--- 1388
Query: 178 TVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTH 237
K+E +K +++ +Q +K +++ K ++E ++ D + V E+ T
Sbjct: 1389 --KKEEKKTFQKSPKQGRKAVQKERKVGKIKREMT---------KEERDMSEEVEEMATL 1437
Query: 238 PELDTDGDGALSEAEAQALLSG-----DTQTDATSFYDRVWAAIRDKYRSEALPTDLPAP 292
E +G L E D + W A ++++ L +
Sbjct: 1438 EEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLH 1497
Query: 293 SAPDLTEPKEEQ----------------PPVPSSPTEEEEEEEEEE---EEEAEEEEEEE 333
A + P+EE + SS ++E++ ++EEE EEE E EE+
Sbjct: 1498 QAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEK 1557
Query: 334 DSEVQGEQPKPASPAEEDKMPP-YDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLE 392
+ +V EQ EE K + ++ +A AQE R +E E+ + + R L
Sbjct: 1558 EQQVTEEQ---RHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEK----LAQEERQLA 1610
Query: 393 QE 394
QE
Sbjct: 1611 QE 1612
Score = 35.8 bits (81), Expect = 0.099
Identities = 72/320 (22%), Positives = 127/320 (39%), Gaps = 61/320 (19%)
Query: 117 KEKGRKERESLQQMAE--------VTREGFRLKKILIE------DWKKAREEKQKKLIEL 162
+E ++ER+ +++ E V +EG K ++IE DWKKA +E ++ E
Sbjct: 1418 REMTKEERDMSEEVEEMATLEEKVVKQEG---KLVMIERTPSWQDWKKAWDEWKQVHGET 1474
Query: 163 QAGKKSLEDQVEMLRTVKEE-----AEK--PEREAKEQHQKL-WEEQLAAAKAQQEQELA 214
+ K+ +++ E +EE EK PE E ++ +KL WEE K E L+
Sbjct: 1475 RKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEW----KQVWENMLS 1530
Query: 215 ADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWA 274
+ + ++ D + E+ E+ +G+ E E Q T+ + WA
Sbjct: 1531 SKSKEQQYKDEE------EVTLEEEVSREGE----EKEQQV-----TEEQRHIQEEHKWA 1575
Query: 275 AIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEED 334
I K R+ A E K Q +EEE+ +EE + A+EE +
Sbjct: 1576 RIHRK-RARA--------------EKKRAQEE--RKLAQEEEKLAQEERQLAQEERKLAQ 1618
Query: 335 SEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 394
+ V+ Q E K +E + + K + + L E + E++
Sbjct: 1619 AYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEK 1678
Query: 395 ISFDFGPNGEFAYLYSQCYE 414
++ G E + +Q E
Sbjct: 1679 LAKKGGKLAEVKNILAQKVE 1698
Score = 30.8 bits (68), Expect = 3.2
Identities = 25/110 (22%), Positives = 54/110 (49%), Gaps = 14/110 (12%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
+E+ R+E E ++ E R ++ E+ + +EE++KK KK E +
Sbjct: 2247 EEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKK-------KKKKEKK---- 2295
Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMD 226
KEE ++ E +E+ + + EE+ + ++E+E + +E+D + +
Sbjct: 2296 ---KEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKE 2342
Score = 30.0 bits (66), Expect = 5.4
Identities = 21/102 (20%), Positives = 54/102 (52%)
Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQ 172
E +E+ +E++ ++ E ++ KK +++ ++ EEK++ + E + S E++
Sbjct: 2267 EERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEE 2326
Query: 173 VEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELA 214
E +++EE ++ + K++ Q +EQ + +E+ L+
Sbjct: 2327 EEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERVLS 2368
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 69.3 bits (168), Expect = 8e-12
Identities = 79/308 (25%), Positives = 135/308 (43%), Gaps = 50/308 (16%)
Query: 118 EKGRKERESLQQMAEVTREGFR--LKKILIEDWKKAREEKQ--KKLIELQAGKKSLEDQV 173
EK KE+E + ++ T + + L K+ E+ ++ REE++ K+L EL+A +K E
Sbjct: 324 EKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEE--- 380
Query: 174 EMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTE 233
R +E+ E+ +++ KE+ ++L +E K+Q+E A+A +L V V
Sbjct: 381 ---RLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQG--VEVPS 435
Query: 234 LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPS 293
+ P+ + E + + + ++ S + AA+ + + P P
Sbjct: 436 KDSLPK-----KRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPV 490
Query: 294 APDLTEPKEE-----------------------QPPVPSSPTEEEEEEEEEEEEEAEEEE 330
P+ E E+ V +P EEEEEEEEEEE+E EEE
Sbjct: 491 EPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEE 550
Query: 331 EEEDSEVQG----EQPKPASPAEE-----DKMPPYDEQTQAFIDAAQEARNKFEEAERSL 381
EEE+ E +G E+ + S ++ DK P + + + D + + R K E A
Sbjct: 551 EEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYD-SDDDRTKEERAYDKA 609
Query: 382 KDMEESIR 389
K E R
Sbjct: 610 KRRIEKRR 617
Score = 38.9 bits (89), Expect = 0.012
Identities = 58/282 (20%), Positives = 110/282 (39%), Gaps = 77/282 (27%)
Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQ 172
E+ K KER + E G + L + + +K K +++G + +
Sbjct: 166 EDEDNSKKIKERSRINSSGE---SGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDAS 222
Query: 173 VEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVT 232
++ +++AEK ERE K++ +E+ A + +E+E
Sbjct: 223 FKIKTVAQKKAEKKERERKKR-----DEEKAKLRKLKEKE-------------------- 257
Query: 233 ELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAP 292
EL+T + E+Q +T + V +PA
Sbjct: 258 ------ELETGKKDQSKQKESQRKFEEETVKSKVTVDTGV----------------IPA- 294
Query: 293 SAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDK 352
+E K E P E +++++++++++ E+EE+E+ E+ K
Sbjct: 295 -----SEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEK---------------EKKK 334
Query: 353 MPPYDEQTQAFIDAAQEARNKF-EEAERSLKDMEESIRNLEQ 393
P ++A + A QEA K EE ER ++ EE I+ LE+
Sbjct: 335 GP-----SKATVKAMQEALAKLKEEEERQKREEEERIKRLEE 371
Score = 34.7 bits (78), Expect = 0.22
Identities = 61/317 (19%), Positives = 124/317 (39%), Gaps = 40/317 (12%)
Query: 117 KEKGRKERES----------LQQMAEVTREGFRLKK----ILIEDWKKAREE---KQKKL 159
K KG+K++E L+++ E++ E +K + ++ + EE K KK
Sbjct: 39 KSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKK 98
Query: 160 IELQAGKKSLED----QVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAA 215
+ K+S +D ++E + ++ KP+ E + KA+ + + +
Sbjct: 99 KGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSN 158
Query: 216 DAFKELDDDMDGTVSVTE---LQTHPELDTDGDGALSEAEAQA----------LLSGDTQ 262
+ ++D D + + E + + E + D L + Q + SG+
Sbjct: 159 KKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNED 218
Query: 263 TDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEE 322
DA+ V +K E D L E KEE ++++E + + E
Sbjct: 219 DDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKE-KEELETGKKDQSKQKESQRKFE 277
Query: 323 EEEAEEEEEEED-----SEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEA 377
EE + + + SE + E P A E D++ + +E K +
Sbjct: 278 EETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPS 337
Query: 378 ERSLKDMEESIRNLEQE 394
+ ++K M+E++ L++E
Sbjct: 338 KATVKAMQEALAKLKEE 354
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 63.9 bits (154), Expect = 3e-10
Identities = 75/306 (24%), Positives = 127/306 (41%), Gaps = 39/306 (12%)
Query: 86 YIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKGRKERESLQQMAEVTREGFRLKKI-- 143
Y P R+N + C G E + + + +QQM RE K++
Sbjct: 270 YAPRLRINKRILALCMGNHELYM---------RRRKPDTIEVQQMKAQAREEKHQKQMER 320
Query: 144 -LIEDWKKARE--EKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEE 200
++E+ KK RE EK+K+ IE + E+ +E L+ ++E+ +K ++E +EQ ++ E
Sbjct: 321 AMLENEKKKREMAEKEKEKIE-----REKEELMERLKQIEEQTKKAQQELEEQTRRALEL 375
Query: 201 QLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGD 260
+ +AQ E E A +E ++ + + + Q T AL AE A +S
Sbjct: 376 EQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQK----KTQEQLALEMAELTARIS-- 429
Query: 261 TQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSA-PDLTEPKEEQPPVPSSPTEEEEEEE 319
Q + R K SEA+ A DL + + E S+P E E
Sbjct: 430 -QLEMA----------RQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAEN 478
Query: 320 EEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDA-AQEARNKFEEAE 378
E++E++ E D K S E +E+ Q + A E N +E++
Sbjct: 479 EQDEQDENGAEASADLRADA-MAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESK 537
Query: 379 RSLKDM 384
++ DM
Sbjct: 538 KTANDM 543
Score = 36.6 bits (83), Expect = 0.058
Identities = 20/73 (27%), Positives = 37/73 (50%)
Query: 315 EEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKF 374
E E+++ E E E+E+ E + E E+ K + +EQT+ ++ QE +
Sbjct: 324 ENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQ 383
Query: 375 EEAERSLKDMEES 387
EAE+ K+ +E+
Sbjct: 384 SEAEKLAKERQEA 396
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 63.5 bits (153), Expect = 4e-10
Identities = 65/247 (26%), Positives = 110/247 (44%), Gaps = 20/247 (8%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKARE-EKQKKLIELQAGKKSLEDQVEM 175
K++ RKE++ + + E RE R K+ E K RE E+QK+ + + D++E
Sbjct: 101 KDEKRKEKKHAR-VKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQ 159
Query: 176 LRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQ---ELAADAFKELDDDMDGTVSVT 232
L +E K + KEQ ++ E+ A + ++ + E++A + + +D V +
Sbjct: 160 LERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH-HRTMREDYSDKVKAS 218
Query: 233 ELQTHP-----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPT 287
P E GDG + + + D +D D ++ S A +
Sbjct: 219 HWSRSPPRPPRERFELGDGR-KPVKEEKMEERDLLSDLQDISD------SERKTSSAESS 271
Query: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEE--EEEEEDSEVQGEQPKPA 345
+ S + E +EE+ S +EE EEEEEEEEEE EE EE SE E+
Sbjct: 272 SAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEE 331
Query: 346 SPAEEDK 352
+E+++
Sbjct: 332 EMSEDEE 338
Score = 36.6 bits (83), Expect = 0.058
Identities = 44/180 (24%), Positives = 75/180 (41%), Gaps = 22/180 (12%)
Query: 117 KEKGRKERE---SLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQV 173
KE+ +ER+ LQ +++ R+ + E + EE++++ E + G S E +
Sbjct: 242 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE- 300
Query: 174 EMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTE 233
EE E+ E E +E E +A+ E+E++ D +E ++
Sbjct: 301 -------EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENEN---------H 344
Query: 234 LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRV--WAAIRDKYRSEALPTDLPA 291
L PE D D SE + + G Q+ A + D V A+ + LP LPA
Sbjct: 345 LLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPA 404
Score = 30.0 bits (66), Expect = 5.4
Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%)
Query: 51 VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110
+ +DY D S + P G KP+ D + D D +D
Sbjct: 207 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 266
Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170
E++ E G E ++ E EG ++ E+ ++ EE++ +A ++S E
Sbjct: 267 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 326
Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194
+ E EE + E E H
Sbjct: 327 EVSE------EEMSEDEERENENH 344
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 63.5 bits (153), Expect = 4e-10
Identities = 65/247 (26%), Positives = 110/247 (44%), Gaps = 20/247 (8%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKARE-EKQKKLIELQAGKKSLEDQVEM 175
K++ RKE++ + + E RE R K+ E K RE E+QK+ + + D++E
Sbjct: 67 KDEKRKEKKHAR-VKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQ 125
Query: 176 LRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQ---ELAADAFKELDDDMDGTVSVT 232
L +E K + KEQ ++ E+ A + ++ + E++A + + +D V +
Sbjct: 126 LERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH-HRTMREDYSDKVKAS 184
Query: 233 ELQTHP-----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPT 287
P E GDG + + + D +D D ++ S A +
Sbjct: 185 HWSRSPPRPPRERFELGDGR-KPVKEEKMEERDLLSDLQDISD------SERKTSSAESS 237
Query: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEE--EEEEEDSEVQGEQPKPA 345
+ S + E +EE+ S +EE EEEEEEEEEE EE EE SE E+
Sbjct: 238 SAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEE 297
Query: 346 SPAEEDK 352
+E+++
Sbjct: 298 EMSEDEE 304
Score = 36.6 bits (83), Expect = 0.058
Identities = 44/180 (24%), Positives = 75/180 (41%), Gaps = 22/180 (12%)
Query: 117 KEKGRKERE---SLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQV 173
KE+ +ER+ LQ +++ R+ + E + EE++++ E + G S E +
Sbjct: 208 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE- 266
Query: 174 EMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTE 233
EE E+ E E +E E +A+ E+E++ D +E ++
Sbjct: 267 -------EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENEN---------H 310
Query: 234 LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRV--WAAIRDKYRSEALPTDLPA 291
L PE D D SE + + G Q+ A + D V A+ + LP LPA
Sbjct: 311 LLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPA 370
Score = 30.0 bits (66), Expect = 5.4
Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%)
Query: 51 VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110
+ +DY D S + P G KP+ D + D D +D
Sbjct: 173 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 232
Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170
E++ E G E ++ E EG ++ E+ ++ EE++ +A ++S E
Sbjct: 233 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 292
Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194
+ E EE + E E H
Sbjct: 293 EVSE------EEMSEDEERENENH 310
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 62.8 bits (151), Expect = 8e-10
Identities = 44/121 (36%), Positives = 59/121 (48%), Gaps = 10/121 (8%)
Query: 283 EALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQP 342
+ +P P P E + SS EEEEEEEEEEEEE EEEEEEED E + E
Sbjct: 859 QLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEE-EEEEEEEDFEEEEED- 916
Query: 343 KPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPN 402
EE+ +E+ + F + +E + EE E ++ EE LE+ +FG
Sbjct: 917 ------EEEYFEEEEEEEEEFEEEFEEEEGELEEEEE--EEDEEEEEELEEVEDLEFGTA 968
Query: 403 G 403
G
Sbjct: 969 G 969
Score = 49.7 bits (117), Expect = 7e-06
Identities = 55/247 (22%), Positives = 100/247 (40%), Gaps = 30/247 (12%)
Query: 165 GKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDD 224
G +LE+ + ++ + E+ E E +E+ ++ EE+ ++E+E + F+E +++
Sbjct: 870 GPPALEEDLTVININSSDEEEEEEEEEEEEEE--EEEEEEEDFEEEEEDEEEYFEEEEEE 927
Query: 225 MDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEA 284
E + E + + +G L E E + + + + D + + A
Sbjct: 928 --------EEEFEEEFEEE-EGELEEEEEEE--DEEEEEELEEVEDLEFGTAGGEVEEGA 976
Query: 285 -----LPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEA-----EEEEEEED 334
LP LP P +P +P+ E P EE EEE + A E + +
Sbjct: 977 PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGE 1036
Query: 335 SEVQGEQPKPASP-----AEEDKMPP--YDEQTQAFIDAAQEARNKFEEAERSLKDMEES 387
E +GE P P EE PP +E+T+ D Q E E + E+
Sbjct: 1037 VEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEA 1096
Query: 388 IRNLEQE 394
++ EQ+
Sbjct: 1097 LQEKEQD 1103
Score = 47.4 bits (111), Expect = 3e-05
Identities = 64/265 (24%), Positives = 101/265 (38%), Gaps = 38/265 (14%)
Query: 110 VICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSL 169
VI N+ E+ +E E ++ E E ED+++ E++++ E + ++
Sbjct: 880 VININSSDEEEEEEEEEEEEEEEEEEEE--------EDFEEEEEDEEEYFEEEEEEEEEF 931
Query: 170 EDQVEMLRTVKEEAEKPEREAKEQHQKLWE-EQLAAAKAQQEQELAADAFKELDDDMDGT 228
E++ E EE E E E +E+ ++L E E L A E E A L +
Sbjct: 932 EEEFEEEEGELEEEE--EEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPP 989
Query: 229 VSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTD 288
S ++Q PE + G L E E A + + + R P
Sbjct: 990 ESPPKVQPEPEPEP---GLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAA 1046
Query: 289 LPAPSAPDLTEPKEEQPPV--------------PSSPTEEEEEEEEEEEEEAEEEEEEED 334
P P +L E + PP P T EEE E E E EA +E+E++D
Sbjct: 1047 GPPPQ--ELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDD 1104
Query: 335 S--------EVQGEQPKPASPAEED 351
+ + + KP P E D
Sbjct: 1105 TAAMLADFIDCPPDDEKPPPPTEPD 1129
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 61.6 bits (148), Expect = 2e-09
Identities = 69/342 (20%), Positives = 142/342 (41%), Gaps = 26/342 (7%)
Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRLKKILIE----DWKKAREEKQKKLIELQAGKKS 168
E +E+ +K RE + M E + + ++ + E +W++ R +QK+ + Q +
Sbjct: 391 EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE 450
Query: 169 LEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQ---EQELAADAFKELDDDM 225
E+++ +EE + + E Q +K+W ++ + Q ++E D +++ D
Sbjct: 451 QEEKI----WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 506
Query: 226 DGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEAL 285
+ E E + + E + TQ +D+ +K R E
Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQ-----EEKMREEER 561
Query: 286 PTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPA 345
+ + +E++ + EE+ E+EE+ E EE+ +E++ ++ ++ K
Sbjct: 562 MREREKKMREEEEMMREQEEKMQEQ--EEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 619
Query: 346 SPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEF 405
EEDKM +E + QE K E E +++ EE +R E+++ G+
Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM------QGQE 673
Query: 406 AYLYSQCYELTTNEYVYRLCPFKLVSQKPKLGGSPTSLGTWG 447
+ Q ++ E R K+ Q+ K+ G + WG
Sbjct: 674 EKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKM--WG 713
Score = 54.7 bits (130), Expect = 2e-07
Identities = 54/285 (18%), Positives = 123/285 (43%), Gaps = 71/285 (24%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
KE+ +E++ + Q E RE + ++ + W + EEK ++ ++ +K + ++ EM+
Sbjct: 519 KEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQ--EEKMREEERMREREKKMREEEEMM 576
Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQT 236
R +E+ ++ E + +EQ +K+WE++ + QEQE + E ++ M ++Q
Sbjct: 577 REQEEKMQEQEEKMREQEEKMWEQE----EKMQEQE---EKMWEQEEKMWEQEEEDKMQE 629
Query: 237 HPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPD 296
E+ + + + E E +++W
Sbjct: 630 QEEMMWEQEEKMQEQE-----------------EKMW----------------------- 649
Query: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPY 356
E+EE+ E+EE+ E+EE+ + E + + + +E+KM
Sbjct: 650 ----------------EQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQ 693
Query: 357 DEQTQAFIDA--AQEARNKFEE----AERSLKDMEESIRNLEQEI 395
+E+ + + QE + +E + +++ EE IR+ ++++
Sbjct: 694 EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKM 738
Score = 52.4 bits (124), Expect = 1e-06
Identities = 59/292 (20%), Positives = 125/292 (42%), Gaps = 19/292 (6%)
Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQ 172
E +E+ K E ++M E + +R ++ L E K+ RE++QK ++ ++ + +Q
Sbjct: 309 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK----MRDQEERMWEQ 364
Query: 173 VEMLRTVKEEAEKPEREAKEQHQKLWEEQL---AAAKAQQEQELAADAFKELDDDMDGTV 229
E LR KEE + + + EQ +K+ EE+ K ++E+E + +++ +
Sbjct: 365 DERLRE-KEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 423
Query: 230 SVTELQTHPELDTDGDGALSEAEAQALLSGD--TQTDATSFYDRVWAAIRDKYRSEALPT 287
E + + + L E E Q + + +W + +R E +
Sbjct: 424 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM-- 481
Query: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEE---EEEDSEVQGEQPKP 344
+ E +E+ ++EE E++E E+EE E++ Q E+ +
Sbjct: 482 ---REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE 538
Query: 345 ASPAEEDKMPPYD-EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 395
+E + +D E+ + +E K E E +++ EE ++ E+++
Sbjct: 539 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 590
Score = 51.2 bits (121), Expect = 2e-06
Identities = 61/299 (20%), Positives = 130/299 (43%), Gaps = 22/299 (7%)
Query: 114 NTCKEKGRKERESLQQMAEVTREG----FRLKKILIEDWKKAREEKQKKLIE---LQAGK 166
NT +E+ ++ E L++ + R+ +R ++ L E K RE+++K + L+ +
Sbjct: 230 NTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQE 289
Query: 167 KSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMD 226
K L +Q + LR K+ E+ E + +EQ +K+WE++ +QE+++ + + +
Sbjct: 290 KELREQEKELREQKKLREQ-EEQMQEQEEKMWEQE--EKMREQEEKMWRQEERLWEQEKQ 346
Query: 227 GTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALP 286
+++ E + D L E E + + R+K E
Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEE 406
Query: 287 T-----DLPAPSAPDLTEPKEEQPPVPSSPTE-----EEEEEEEEEEEEAEEEEEEEDSE 336
T + ++ E +E++ P + E+E+ +E+EE+ E+EE+ D E
Sbjct: 407 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 466
Query: 337 VQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 395
Q K ++KM ++Q + ++ K + E + + +E +R E+ +
Sbjct: 467 EMWGQEK--KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERM 523
Score = 49.7 bits (117), Expect = 7e-06
Identities = 58/274 (21%), Positives = 112/274 (40%), Gaps = 43/274 (15%)
Query: 129 QMAEVTREGFRLKKILIEDWKKAREEKQK-----KLIELQAGKKSLEDQVEMLRTVKEEA 183
Q + E +R ++ L E KK R++++K + + Q GK + +Q E +R ++
Sbjct: 228 QTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGK--MREQEEKMRRQEKRL 285
Query: 184 EKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTD 243
+ E+E +EQ ++L E++ + +Q QE +++ + +++ E
Sbjct: 286 REQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEE----------KMREQEEKMWR 335
Query: 244 GDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEE 303
+ L E E Q D +R+W + KEE
Sbjct: 336 QEERLWEQEKQMREQEQKMRDQE---ERMW-------------------EQDERLREKEE 373
Query: 304 QPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAF 363
+ E+EE+ +EEE E++ E+ E EQ + EE+ +++ Q
Sbjct: 374 RMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ 433
Query: 364 IDAAQEAR----NKFEEAERSLKDMEESIRNLEQ 393
Q+ + K +E E + + EE IR+ E+
Sbjct: 434 RLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEE 467
Score = 32.0 bits (71), Expect = 1.4
Identities = 21/89 (23%), Positives = 40/89 (44%), Gaps = 13/89 (14%)
Query: 307 VPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDA 366
+P T +EE +EEE E+E++ + E+KM +E+ +
Sbjct: 224 LPQVQTNTLQEEMWRQEEELREQEKKIRKQ-------------EEKMWRQEERLREQEGK 270
Query: 367 AQEARNKFEEAERSLKDMEESIRNLEQEI 395
+E K E+ L++ E+ +R E+E+
Sbjct: 271 MREQEEKMRRQEKRLREQEKELREQEKEL 299
Score = 31.2 bits (69), Expect = 2.4
Identities = 23/93 (24%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Query: 305 PPVPSSPTEEE--EEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQA 362
P V ++ +EE +EEE E+E + ++EE Q E+ + +E KM +E+ +
Sbjct: 225 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLR----EQEGKMREQEEKMRR 280
Query: 363 FIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 395
+E + E E+ L++ ++ +R E+++
Sbjct: 281 QEKRLREQEKELREQEKELRE-QKKLREQEEQM 312
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 60.5 bits (145), Expect = 4e-09
Identities = 70/302 (23%), Positives = 124/302 (41%), Gaps = 47/302 (15%)
Query: 107 NSGVICENTCKEKGRKERESL-----QQMAEVTREGFRLKKILIEDWKKAREEKQKKLIE 161
NS E++ +++G +E +SL QQM+ R +K+ +K +E+++ +
Sbjct: 30 NSPYRREDSMEDRG-EEDDSLAIKPPQQMS-------RKEKVHHRKDEKRKEKRRHRSHS 81
Query: 162 LQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKEL 221
+ GK + + E + E K RE +++ ++ WE Q A++ D ++L
Sbjct: 82 AEGGKHARVKEKER----EHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQL 137
Query: 222 DDDMDGTVSVTELQTHP----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAI- 276
+ + + E Q E + + E EA+ +S +T + D+V A+
Sbjct: 138 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 197
Query: 277 ----------------------RDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPS---SP 311
+K L +DL S + E S S
Sbjct: 198 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 257
Query: 312 TEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEAR 371
EEEEEEEEEEE EE EEE+ E + E+ + S +EE +E ++ + +E
Sbjct: 258 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 317
Query: 372 NK 373
N+
Sbjct: 318 NE 319
Score = 30.0 bits (66), Expect = 5.4
Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%)
Query: 51 VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110
+ +DY D S + P G KP+ D + D D +D
Sbjct: 184 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 243
Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170
E++ E G E ++ E EG ++ E+ ++ EE++ +A ++S E
Sbjct: 244 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 303
Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194
+ E EE + E E H
Sbjct: 304 EVSE------EEMSEDEERENENH 321
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 60.5 bits (145), Expect = 4e-09
Identities = 70/302 (23%), Positives = 124/302 (41%), Gaps = 47/302 (15%)
Query: 107 NSGVICENTCKEKGRKERESL-----QQMAEVTREGFRLKKILIEDWKKAREEKQKKLIE 161
NS E++ +++G +E +SL QQM+ R +K+ +K +E+++ +
Sbjct: 64 NSPYRREDSMEDRG-EEDDSLAIKPPQQMS-------RKEKVHHRKDEKRKEKRRHRSHS 115
Query: 162 LQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKEL 221
+ GK + + E + E K RE +++ ++ WE Q A++ D ++L
Sbjct: 116 AEGGKHARVKEKER----EHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQL 171
Query: 222 DDDMDGTVSVTELQTHP----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAI- 276
+ + + E Q E + + E EA+ +S +T + D+V A+
Sbjct: 172 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 231
Query: 277 ----------------------RDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPS---SP 311
+K L +DL S + E S S
Sbjct: 232 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 291
Query: 312 TEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEAR 371
EEEEEEEEEEE EE EEE+ E + E+ + S +EE +E ++ + +E
Sbjct: 292 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 351
Query: 372 NK 373
N+
Sbjct: 352 NE 353
Score = 30.0 bits (66), Expect = 5.4
Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%)
Query: 51 VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110
+ +DY D S + P G KP+ D + D D +D
Sbjct: 218 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 277
Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170
E++ E G E ++ E EG ++ E+ ++ EE++ +A ++S E
Sbjct: 278 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 337
Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194
+ E EE + E E H
Sbjct: 338 EVSE------EEMSEDEERENENH 355
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 60.1 bits (144), Expect = 5e-09
Identities = 66/279 (23%), Positives = 114/279 (40%), Gaps = 13/279 (4%)
Query: 107 NSGVICENTCKEKGRKERESL-----QQMAEVTREGFRLKKILIEDWK----KAREEKQK 157
NS E++ +++G +E +SL QQM+ + R + E WK K RE +++
Sbjct: 64 NSPYRREDSMEDRG-EEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERR 122
Query: 158 KLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADA 217
K + K E + + R + E + ER+ EQ ++ E + + Q+EQ +
Sbjct: 123 KRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKER 182
Query: 218 FKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIR 277
+ ++ + E+ H + +A + + D
Sbjct: 183 ERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKE 242
Query: 278 DKYRSEALPTDLPAPSAPDLTEPKEEQPPVPS---SPTEEEEEEEEEEEEEAEEEEEEED 334
+K L +DL S + E S S EEEEEEEEEEE EE EEE+
Sbjct: 243 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 302
Query: 335 SEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNK 373
E + E+ + S +EE +E ++ + +E N+
Sbjct: 303 EEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 341
Score = 30.0 bits (66), Expect = 5.4
Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%)
Query: 51 VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110
+ +DY D S + P G KP+ D + D D +D
Sbjct: 206 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 265
Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170
E++ E G E ++ E EG ++ E+ ++ EE++ +A ++S E
Sbjct: 266 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 325
Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194
+ E EE + E E H
Sbjct: 326 EVSE------EEMSEDEERENENH 343
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 59.7 bits (143), Expect = 6e-09
Identities = 56/276 (20%), Positives = 124/276 (44%), Gaps = 21/276 (7%)
Query: 122 KERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKE 181
K RE +++ E ++ +R ++ + E K EEK+++ E+ ++ + +Q E+ R KE
Sbjct: 438 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQ-KE 496
Query: 182 EAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELD 241
+ + E + ++Q +K+W ++ K ++++E + +++ + E+ E
Sbjct: 497 KMHEQEEKIRKQEEKVWRQE---EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKM 553
Query: 242 TDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPK 301
+ + E + Q D++W +K R + + E +
Sbjct: 554 HEQEKIWEEEKRQEQ------------EDKMWRQ-EEKIREQEEKVWRQEEKIREQEEKR 600
Query: 302 EEQPPVPSSPTEE-EEEEEEEEEEE---AEEEEEEEDSEVQGEQPKPASPAEEDKMPPYD 357
+EQ E+ E+EE+ +E+E E+EE+ + E ++ + +E+KM +
Sbjct: 601 QEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE 660
Query: 358 EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 393
E+ Q + K E E+ +++ EE IR E+
Sbjct: 661 EKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
Score = 51.6 bits (122), Expect = 2e-06
Identities = 57/296 (19%), Positives = 131/296 (44%), Gaps = 18/296 (6%)
Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREE--KQKKLI----ELQAGK 166
E +E+ K RE ++M + +KI E+ ++ +EE +Q++ I E+ K
Sbjct: 436 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQK 495
Query: 167 KSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMD 226
+ + +Q E +R +E+ + E + +EQ +K+ E++ + +++ + ++E ++ M
Sbjct: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE-EEKMH 554
Query: 227 GTVSVTELQTHPELDTD---GDGALSEAEAQALLSGDT----QTDATSFYDRVWAAIRDK 279
+ E + E + + + E E + + + +++W +K
Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ-EEK 613
Query: 280 YRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQG 339
R + + E EQ + E+EE+ E+EE+ E+EE+ ++ E
Sbjct: 614 IREQEEKIQEQEEKIREQEEKIREQEEMTQ---EQEEKMGEQEEKMCEQEEKMQEQEETM 670
Query: 340 EQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 395
+ + +E K+ +E+ + + QE K E E + + EE ++ E+++
Sbjct: 671 WRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 726
Score = 50.4 bits (119), Expect = 4e-06
Identities = 58/311 (18%), Positives = 136/311 (43%), Gaps = 41/311 (13%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWK-KAREEKQKKLIELQAGKKSLEDQVEM 175
+EK R++ E + + E RE L++ + E K + +EEK+++ +++ +K E + +M
Sbjct: 376 EEKMRRQEEMMWEKEEKIRE---LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 432
Query: 176 LRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDM----DGTVSV 231
R +E+ + E + +EQ +K+W ++ K +++++ + ++ ++M +
Sbjct: 433 WRQ-EEKIREQEEKIREQEKKMWRQE---EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQ 488
Query: 232 TELQTHPELDTDGDGALSEAEAQALLSGDT-----------------QTDATSFYDRVWA 274
E+ E + + + + E + + Q + + +W
Sbjct: 489 EEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWR 548
Query: 275 AIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEE-EEEEEEEAEEEEE-- 331
+ E + + D +EE+ +EE+ E+EE+ E+EE+
Sbjct: 549 EEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMW 608
Query: 332 -------EEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDM 384
E++ ++Q ++ K +E+K+ +E TQ + E K E E +++
Sbjct: 609 KQEEKIREQEEKIQEQEEKIRE--QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 666
Query: 385 EESIRNLEQEI 395
EE++ E++I
Sbjct: 667 EETMWRQEEKI 677
Score = 47.8 bits (112), Expect = 3e-05
Identities = 52/292 (17%), Positives = 123/292 (42%), Gaps = 22/292 (7%)
Query: 113 ENTCKEKGRKERESLQQMAEVTREG---FRLKKILIEDWKKAREEKQKKLIELQAGKKSL 169
E +E+ R+E+E + + E E +R K+ + E +K R++++K + ++ +
Sbjct: 464 EKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEK----VWRQEEKI 519
Query: 170 EDQVEMLRTVKEEAEKPEREAKEQHQ------------KLWEEQLAAAKAQQEQELAADA 217
+Q E +R +E+ + E + +EQ + K+WEE+ + +QE ++
Sbjct: 520 REQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEE---KRQEQEDKMWRQE 576
Query: 218 FKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIR 277
K + + +++ E + + + + E + + + IR
Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR 636
Query: 278 DKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEV 337
++ + + E +E+ + +EE+ E+E++ E+EE+ + E
Sbjct: 637 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
Query: 338 QGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIR 389
++ + +E+KM +E+ Q + + K E E L+ EE ++
Sbjct: 697 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
Score = 37.4 bits (85), Expect = 0.034
Identities = 22/83 (26%), Positives = 41/83 (49%)
Query: 313 EEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARN 372
E+EE+ E+EE+ E+EE+ E + + +E+ M +E+ + + E
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 377
Query: 373 KFEEAERSLKDMEESIRNLEQEI 395
K E + + EE IR LE+++
Sbjct: 378 KMRRQEEMMWEKEEKIRELEEKM 400
Score = 36.6 bits (83), Expect = 0.058
Identities = 57/300 (19%), Positives = 115/300 (38%), Gaps = 53/300 (17%)
Query: 105 EYNSGVICENTCKEKGRKERESLQ-----------QMAEVTREGFRLKKILIEDWKKARE 153
E I + KEK K +E LQ + E+ R+ R K +L + +A
Sbjct: 208 ELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA 267
Query: 154 EKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQEL 213
+ K ELQ+ L+ QVE E E R ++Q +K+W ++ + +++ +
Sbjct: 268 DHLGK--ELQSVSAKLQAQVE-------ENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 318
Query: 214 AADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVW 273
+ +E ++ + +++ E+ + + + E + +W
Sbjct: 319 QEEKIREQEEKI--REQEEKMRRQEEMMWEKEEKMRRQE-----------------EMMW 359
Query: 274 AAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEE 333
R E + + KEE+ E+EE+ E EE+ E+E+
Sbjct: 360 EKEEKMRRQEEMMWE------------KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 407
Query: 334 DSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 393
+ E + ++ + E++K + + + +E K E E+ + EE I E+
Sbjct: 408 EQEEKRQEEEKI--REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK 465
Score = 36.2 bits (82), Expect = 0.075
Identities = 53/285 (18%), Positives = 114/285 (40%), Gaps = 21/285 (7%)
Query: 115 TCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVE 174
T K+K + E L + + I E+ K+ + Q+KL +++ K ++ V+
Sbjct: 186 TQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVK 245
Query: 175 MLRTVKEEAEK--PEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVT 232
L+ E A+ P+++ + + L +E + + Q Q + + L+ + +
Sbjct: 246 ELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQ 305
Query: 233 E--LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLP 290
E +Q E + + + E E + + + + +W R E +
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIR---EQEEKMRRQEEMMWEKEEKMRRQEEM----- 357
Query: 291 APSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEE 350
+ E +E+ E+EE+ +EE E+EE+ + E + + + EE
Sbjct: 358 ------MWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 411
Query: 351 DKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 395
+ +E+ + QE K E +++ EE IR E+++
Sbjct: 412 KRQ---EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM 453
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 59.3 bits (142), Expect = 8e-09
Identities = 64/250 (25%), Positives = 106/250 (42%), Gaps = 22/250 (8%)
Query: 117 KEKGRKERESLQ--QMAEVTREGFRLKKILIEDWKKAREE--KQKKLIELQAGKKSLEDQ 172
KEK R S + + A V +K E+ KAR E +QK+ + + D+
Sbjct: 106 KEKCRHHSHSAEGGKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDR 165
Query: 173 VEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQ---ELAADAFKELDDDMDGTV 229
+E L +E K + KEQ ++ E+ A + ++ + E++A + + +D V
Sbjct: 166 LEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH-HRTMREDYSDKV 224
Query: 230 SVTELQTHP-----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEA 284
+ P E GDG + + + D +D D ++ S A
Sbjct: 225 KASHWSRSPPRPPRERFELGDGR-KPVKEEKMEERDLLSDLQDISD------SERKTSSA 277
Query: 285 LPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEE--EEEEEDSEVQGEQP 342
+ + S + E +EE+ S +EE EEEEEEEEEE EE EE SE E+
Sbjct: 278 ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEV 337
Query: 343 KPASPAEEDK 352
+E+++
Sbjct: 338 SEEEMSEDEE 347
Score = 56.2 bits (134), Expect = 7e-08
Identities = 53/224 (23%), Positives = 88/224 (39%), Gaps = 30/224 (13%)
Query: 180 KEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHP- 238
+ E K RE +++ ++ WE Q A++ D ++L+ + + E Q
Sbjct: 128 EHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQR 187
Query: 239 ---ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAI------------------- 276
E + + E EA+ +S +T + D+V A+
Sbjct: 188 EQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGR 247
Query: 277 ----RDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPS---SPTEEEEEEEEEEEEEAEEE 329
+K L +DL S + E S S EEEEEEEEEEE EE
Sbjct: 248 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 307
Query: 330 EEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNK 373
EEE+ E + E+ + S +EE +E ++ + +E N+
Sbjct: 308 SEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 351
Score = 36.2 bits (82), Expect = 0.075
Identities = 44/180 (24%), Positives = 75/180 (41%), Gaps = 22/180 (12%)
Query: 117 KEKGRKERE---SLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQV 173
KE+ +ER+ LQ +++ R+ + E + EE++++ E + G S E +
Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE- 309
Query: 174 EMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTE 233
EE E+ E E +E E +A+ E+E++ D +E ++
Sbjct: 310 -------EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENEN---------H 353
Query: 234 LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRV--WAAIRDKYRSEALPTDLPA 291
L PE D D SE + + G Q+ A + D V A+ + LP LPA
Sbjct: 354 LLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPA 413
Score = 30.0 bits (66), Expect = 5.4
Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%)
Query: 51 VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110
+ +DY D S + P G KP+ D + D D +D
Sbjct: 216 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 275
Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170
E++ E G E ++ E EG ++ E+ ++ EE++ +A ++S E
Sbjct: 276 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 335
Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194
+ E EE + E E H
Sbjct: 336 EVSE------EEMSEDEERENENH 353
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 59.3 bits (142), Expect = 8e-09
Identities = 58/283 (20%), Positives = 123/283 (43%), Gaps = 41/283 (14%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIE--LQAGKKSLEDQVE 174
KE+ +E+E + + E RE +K + E KK R++++K E ++ +K + ++ E
Sbjct: 409 KEERMREQEKMWEQVEKMRE----EKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEE 464
Query: 175 MLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQ--EQELAADAFKELDDDMDGTVSVT 232
+R +E+ +K E EQ +K W++Q + ++ EQE
Sbjct: 465 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE-------------------- 504
Query: 233 ELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAP 292
++Q E + + + + E + G + ++W ++K R +
Sbjct: 505 KMQEQEEKIWEQEEKIRDQEE---MWGQEK--------KMWR--QEKMREQEDQMWEQEE 551
Query: 293 SAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDK 352
D + +Q T+E+E++ ++EE+ EEE + E + + + +E+K
Sbjct: 552 KMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK 611
Query: 353 MPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 395
M +E+ Q + E K +E E + + EE + E+++
Sbjct: 612 MQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM 654
Score = 58.9 bits (141), Expect = 1e-08
Identities = 58/291 (19%), Positives = 124/291 (42%), Gaps = 17/291 (5%)
Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKA--REEKQKKLIELQAGKKSLE 170
E+ E+ K R+ Q+M + R++K E KK +EEK ++ ++ +K +
Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEE---RMEKKTQEQEKKTWDQEEKMREEERMREREKKMR 599
Query: 171 DQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVS 230
++ EM+R +E+ ++ E + +EQ +K+WE++ + +++ + E ++ M
Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659
Query: 231 VTE----LQTHPELDTDGDGALSEAEA--QALLSGDTQTDATSFYDRVWAAIRDKYRSEA 284
+ E L H ++ E + Q + TQ +D+ +K R E
Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQ------EKMREEE 713
Query: 285 LPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKP 344
+ + +E++ + + +E+EEE E+E + E+EE Q P+
Sbjct: 714 SMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQ 773
Query: 345 ASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 395
E + E+ + ++ K E ++ EE +R E+++
Sbjct: 774 KEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKM 824
Score = 56.6 bits (135), Expect = 5e-08
Identities = 56/299 (18%), Positives = 131/299 (43%), Gaps = 24/299 (8%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEM- 175
+EK +K+ E++ + E + RL + + W++ + ++Q++ I Q K + DQ EM
Sbjct: 470 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK--IRDQEEMW 527
Query: 176 -----------LRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAA-DAFKELDD 223
+R +++ + E + ++Q QK+W+++ K QEQE D +++ +
Sbjct: 528 GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMRE 587
Query: 224 DMDGTVSVTELQTHPELDTDGDGALSEAEA----QALLSGDTQTDATSFYDRVWAAIRDK 279
+ +++ E+ + + + E E Q + + +++W
Sbjct: 588 EERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKM 647
Query: 280 YRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQG 339
+ E + P+ E E + +E+EE+ E+E+ E++ +E++ +
Sbjct: 648 WEQEEKMWE--QQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWD 705
Query: 340 EQP---KPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 395
++ + + E KM +E + + QE K +E E + + EE + E+++
Sbjct: 706 QEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKM 764
Score = 50.4 bits (119), Expect = 4e-06
Identities = 63/291 (21%), Positives = 123/291 (42%), Gaps = 25/291 (8%)
Query: 123 ERESLQ-QMAEVTREGFRLKKILIE-DWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK 180
E+ +Q + E+ R+ R K +L + +EE ++ EL+ +K + Q E + +
Sbjct: 240 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQE 299
Query: 181 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL 240
E + E + +EQ +K+W ++ +QE+EL + KEL + + ++Q E
Sbjct: 300 ERLREQEGKMREQEEKMWRQE--KRLREQEKEL-REQEKELREQKELREQEEQMQEQEEK 356
Query: 241 DTDGDGALSEAE-----------AQALLSGDTQTDATSFYDRVW---AAIRDKYRSEALP 286
+ + + E E Q + + +R+W +R+K
Sbjct: 357 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK-EERMRE 415
Query: 287 TDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPAS 346
+ + E K+ Q + +EE+ +EEE E E++ EE+ E EQ +
Sbjct: 416 QEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEE-ETMREQEEKMQ 474
Query: 347 PAEEDKMPPYDEQTQAFIDAAQEAR----NKFEEAERSLKDMEESIRNLEQ 393
EE+ +++ Q Q+ + K +E E + + EE IR+ E+
Sbjct: 475 KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEE 525
Score = 46.6 bits (109), Expect = 6e-05
Identities = 54/301 (17%), Positives = 124/301 (41%), Gaps = 36/301 (11%)
Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKA--REEKQKKLIELQAGKKSLE 170
E +E+ K +E ++M E + + ++ + E +K +EEK + E ++ L
Sbjct: 602 EEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 661
Query: 171 DQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVS 230
+Q E L + E + + + +EQ +K+WE++ K Q++++ D K +++
Sbjct: 662 EQKEKLW--EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE-SMRER 718
Query: 231 VTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLP 290
+++ E+ + + + E E + + + + +++W + + LP
Sbjct: 719 EKKMREEEEMMREQEEKMQEQEEKMQ---EQEEEMWEQEEKMWEQEEKMWEQQRLPEQ-- 773
Query: 291 APSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAE- 349
L E ++ Q EE+ ++EE+ EE+ ++ +++G++ K E
Sbjct: 774 ---KEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEK 830
Query: 350 ----------------------EDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEES 387
E+KM +E+ + + + K E E ++ EE
Sbjct: 831 MWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Query: 388 I 388
I
Sbjct: 891 I 891
Score = 46.2 bits (108), Expect = 7e-05
Identities = 59/287 (20%), Positives = 121/287 (42%), Gaps = 39/287 (13%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
+EK +E++ L++ E +E ++ + E +K RE+++K + ++ L +Q + +
Sbjct: 333 QEKELREQKELREQEEQMQEQ---EEKMWEQEEKMREQEEK----MWRQEERLWEQEKQM 385
Query: 177 RTVKEEAEKPEREAKEQHQKL--WEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTEL 234
R +++ E EQ ++L EE++ + EQ K++ + T E
Sbjct: 386 REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445
Query: 235 QTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSA 294
E + + + E E + + + +W +++ + LP
Sbjct: 446 MQEEERIREREKKMREEEE---TMREQEEKMQKQEENMWEQEEKEWQQQRLP-------- 494
Query: 295 PDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPK----PASPAEE 350
E KE+ E+E+ +E+EE+ +EE+ + E+ G++ K +E
Sbjct: 495 ----EQKEKL-------WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 543
Query: 351 DKMPPYDE----QTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 393
D+M +E Q Q D + K +E E+ D EE +R E+
Sbjct: 544 DQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEER 590
Score = 40.4 bits (93), Expect = 0.004
Identities = 56/287 (19%), Positives = 117/287 (40%), Gaps = 49/287 (17%)
Query: 118 EKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLR 177
E+ KER++L E+ R I E+ KK E Q+KL ++ K ++ V+ L+
Sbjct: 200 EELTKERDALS--LELYRN-----TITNEELKKKNAELQEKLPLAESEKSEIQLNVKELK 252
Query: 178 TVKEEAE--KPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQ 235
E A+ P+ + +++W +QE+EL K + ++
Sbjct: 253 RKLERAKFLLPQVQTNTLQEEMW---------RQEEELREQEKKIRKQE-------EKMW 296
Query: 236 THPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRD--KYRSEALPTDLPAPS 293
E + +G + E E +++W + + E +
Sbjct: 297 RQEERLREQEGKMREQE-----------------EKMWRQEKRLREQEKELREQEKELRE 339
Query: 294 APDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKM 353
+L E +E+ E+EE+ E+EE+ +EE + E Q + + +E++M
Sbjct: 340 QKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM 399
Query: 354 PPYDEQTQAFIDAAQEARNKFEEA-----ERSLKDMEESIRNLEQEI 395
DE+ + + +E +E+ E+ +++ E+ R+ E+++
Sbjct: 400 WEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKM 446
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 58.5 bits (140), Expect = 1e-08
Identities = 68/306 (22%), Positives = 129/306 (42%), Gaps = 22/306 (7%)
Query: 113 ENTCKEKGRKERESLQQMAEVTR-EGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLED 171
E K + + R+ L++ E R E R K+ L D ++ R E+ KL E + ++ E
Sbjct: 444 EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEE-EERREQQER 502
Query: 172 QVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSV 231
+ + LR +EE + + +E+ ++L + + + ++EQE + + +++
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562
Query: 232 TELQTHPELDTDGDGAL--SEAEAQALLSGDTQTDATSFYDR--VWAAIRDKYRSEALPT 287
E + E + D L E Q L + + R V +++ R + L
Sbjct: 563 REQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKR 622
Query: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEE-------EEEEEEEAEE------EEEEED 334
+ P EEQ E++E EEEEE E+ EEE +
Sbjct: 623 EEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERRE 682
Query: 335 SEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQE---ARNKFEEAERSLKDMEESIRNL 391
E+ E+ + A + ++P + Q ++ DA Q +R + +E +R ++ EE R
Sbjct: 683 QELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRR 742
Query: 392 EQEISF 397
E E+ +
Sbjct: 743 ESELQW 748
Score = 49.7 bits (117), Expect = 7e-06
Identities = 55/285 (19%), Positives = 119/285 (41%), Gaps = 16/285 (5%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
K++ R+ER+ E +E + + +L ++ +K +EE+ ++ ELQ E++ ++
Sbjct: 226 KQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ------EEEEQLR 279
Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQT 236
+ ++E + +E ++Q Q+L EQ K ++E+ + +E + + E Q
Sbjct: 280 KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQL 339
Query: 237 HPELDTDGDGAL----SEAEAQALLSGDTQTDATSFYDRVWAAIRDKY---RSEALPTDL 289
E + + L E + L + + + R +R + R + L +
Sbjct: 340 RREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQ 399
Query: 290 PAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAE 349
L ++ + ++ E+EEE E + E+E + ++ EQ + +
Sbjct: 400 QLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLK 459
Query: 350 EDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 394
++ EQ + Q R++ EE +EE R +QE
Sbjct: 460 REEETERHEQERR---KQQLKRDQEEERRERWLKLEEEERREQQE 501
Score = 48.5 bits (114), Expect = 1e-05
Identities = 60/289 (20%), Positives = 121/289 (41%), Gaps = 21/289 (7%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
KE+ + + E Q+ E+ E +L+K+ ++ ++ R+E++++ L+ ++ L + E
Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR-EQQLRRKQEEE 313
Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQT 236
R ++E + ++E +EQ ++ E+QL + +QE+ +E +++ E Q
Sbjct: 314 RREQQEERREQQERREQQEERREQQL---RREQEERREQQLRREQEEER------REQQL 364
Query: 237 HPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPD 296
E + + E Q + + ++ + R + L +
Sbjct: 365 RREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 424
Query: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEE------AEEEEEEEDSEVQGEQPKPASPAEE 350
L +EE+ E E+ + E+EE EEE E + E + +Q K E
Sbjct: 425 LRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEER 484
Query: 351 D----KMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 395
K+ + + Q Q R + E E+ LK EE R L+Q +
Sbjct: 485 RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEER-LQQRL 532
Score = 48.5 bits (114), Expect = 1e-05
Identities = 67/282 (23%), Positives = 120/282 (42%), Gaps = 45/282 (15%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
+E+ R+ERE QQ++ R+ +K +E+ K R+E+++K +ED+ ++
Sbjct: 1560 EEQLRQEREE-QQLSRQERD----RKFRLEEQKVRRQEQERKF---------MEDEQQLR 1605
Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQT 236
R ++ + ER+ K + +EQL + +Q+ K L+++ + +
Sbjct: 1606 RQEGQQQLRQERDRKFRE----DEQLLQEREEQQLHRQERDRKFLEEE----PQLRRQER 1657
Query: 237 HPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPD 296
+L D D E E Q L G+ Q DR K+R E
Sbjct: 1658 EQQLRHDRDRKFRE-EEQLLQEGEEQQLRRQERDR-------KFREEEQQLRRQERERKF 1709
Query: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPY 356
L E ++ + +E E + EEE+ +E E+E Q + EE+++ P
Sbjct: 1710 LQEEQQLR--------RQELERKFREEEQLRQETEQEQLR---RQERYRKILEEEQLRPE 1758
Query: 357 DEQTQAFIDAAQEARNKFEEAERSLKDMEE-SIRNLEQEISF 397
E+ Q QE KF E E+ ++ EE +R+ E + F
Sbjct: 1759 REEQQL---RRQERDRKFREEEQLRQEREEQQLRSQESDRKF 1797
Score = 46.6 bits (109), Expect = 6e-05
Identities = 60/293 (20%), Positives = 126/293 (43%), Gaps = 22/293 (7%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQ-----KKLIELQAGKKSLED 171
+E+ RKE++ LQ+ E + R K+ E ++ REE+Q ++L+ + K+ ++
Sbjct: 896 QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE 955
Query: 172 QVEMLRT-----VKEE---AEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDD 223
+ R KEE E+PE+ +++ +K + E+ + ++EQ L + K
Sbjct: 956 RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE-EELQQEEEQLLREEREKRRRQ 1014
Query: 224 DMDGTVSVTELQTHPELDTDGDGAL-SEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRS 282
+ + + + EL + + L E E + L + Q + + + R
Sbjct: 1015 EWE-----RQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERE 1069
Query: 283 EALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQP 342
+L + +EE+ + P + +E E + E EE ++EE+ ++ E+
Sbjct: 1070 TRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREERE 1129
Query: 343 KPASPAEEDKMPPYDE--QTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 393
K E + +E Q + + + + + +E ER ++ EE + EQ
Sbjct: 1130 KRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQ 1182
Score = 44.7 bits (104), Expect = 2e-04
Identities = 60/281 (21%), Positives = 122/281 (43%), Gaps = 30/281 (10%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
+ + +K R L++ + R K L E +K ++ Q++ ELQ ++ + E
Sbjct: 868 QRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQE 927
Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAAD-AFKELDDDMDGTVSVTELQ 235
R +EE E+ +E+ Q L EE+ + ++E++ D ++ ++ + G +
Sbjct: 928 RQYREE----EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR 983
Query: 236 THPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAP 295
E + L + E Q LL + + ++R +YR + +L
Sbjct: 984 QEREKKYREEEELQQEEEQ-LLREEREKRRRQEWER-------QYRKK---DELQQEEEQ 1032
Query: 296 DLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEE---EDSEVQGEQPKPASPAEEDK 352
L E +E++ +E E + EEEE ++EEE+ E+ E + Q +E++
Sbjct: 1033 LLREEREKR-------RLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
Query: 353 MPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 393
+ +EQ + + + + +E ER ++ EE + EQ
Sbjct: 1086 LQQEEEQ----LLREEPEKRRRQERERQCREEEELQQEEEQ 1122
Score = 43.9 bits (102), Expect = 4e-04
Identities = 65/310 (20%), Positives = 125/310 (40%), Gaps = 61/310 (19%)
Query: 121 RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK 180
RKE E Q+ ++ RE E K+ R+E++++ E ++ L+ + E L ++
Sbjct: 1081 RKEEELQQEEEQLLRE---------EPEKRRRQERERQCRE----EEELQQEEEQL--LR 1125
Query: 181 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL 240
EE EK R+ E+ + EE + ++EQ L + K +++ + + EL
Sbjct: 1126 EEREKRRRQELERQYREEEE----VQQEEEQLLREEPEKRRRQELE-----RQYREEEEL 1176
Query: 241 DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP 300
+ + L E + + + Q R + +YR E +DL P+
Sbjct: 1177 QQEEEQLLREEQEKRRQERERQYREEEELQR--QKRKQRYRDEDQRSDLKWQWEPEKENA 1234
Query: 301 --------------------------KEEQPPVPSSPTEEEEEEEEEEEEEAEE------ 328
++ Q + E++E + E+E ++
Sbjct: 1235 VRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFP 1294
Query: 329 EEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEES- 387
EEE+ + E Q E + ++E+K +E+ + QE KF E E+ L++ EE
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEK--RRRQETDRKFREEEQLLQEREEQP 1352
Query: 388 IRNLEQEISF 397
+R E++ F
Sbjct: 1353 LRRQERDRKF 1362
Score = 43.1 bits (100), Expect = 6e-04
Identities = 58/270 (21%), Positives = 111/270 (41%), Gaps = 33/270 (12%)
Query: 121 RKERESLQQMAEVTREGFRLKKILIEDWKKA---REEKQKKLIELQAGKKSLEDQVEMLR 177
R +RE ++++ + R RLK+ E+ ++ + E+Q++ + Q ++ E + + L+
Sbjct: 601 RLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLK 660
Query: 178 TVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFK--------ELDDDMDGTV 229
+EE E+ E+ K +H+ EE+ A++EQE A + K +L+ + D
Sbjct: 661 R-EEEEERLEQRLKREHE---EERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQ 716
Query: 230 SVT-----------ELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAI-- 276
S Q E + L E + + + + W A
Sbjct: 717 SKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEK 776
Query: 277 --RDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEE--E 332
R + R A P L L + +Q P EEE+E+ + E E+E + E
Sbjct: 777 SERGRQRLSARPP-LREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLE 835
Query: 333 EDSEVQGEQPKPASPAEEDKMPPYDEQTQA 362
E+ ++Q + EED + E+ ++
Sbjct: 836 EEEQLQRRERAQQLQEEEDGLQEDQERRRS 865
Score = 42.4 bits (98), Expect = 0.001
Identities = 55/237 (23%), Positives = 97/237 (40%), Gaps = 43/237 (18%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIE-----LQAGKKSLED 171
+E+ RK RE QQ+ RE +K L E+ + R+E ++K E + ++ L
Sbjct: 1687 QERDRKFREEEQQLRRQERE----RKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRR 1742
Query: 172 QVEMLRTVKEEAEKPEREAK-----EQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMD 226
Q + ++EE +PERE + E+ +K EE+ + +++Q + ++ ++ ++
Sbjct: 1743 QERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQ 1802
Query: 227 GTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALP 286
E Q P+ DG E Q L Q R+ +YR+E
Sbjct: 1803 LRQEREEQQLRPQ---QRDGKYRWEEEQLQLEEQEQ--------RLRQERDRQYRAE--- 1848
Query: 287 TDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPK 343
E+ S EE+E +EEE++ +E E + E Q K
Sbjct: 1849 ---------------EQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQK 1890
Score = 42.0 bits (97), Expect = 0.001
Identities = 57/284 (20%), Positives = 119/284 (41%), Gaps = 21/284 (7%)
Query: 116 CKEKGRKERESLQQMAEVTREGFR-LKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVE 174
CK + ++ L+ R+ + L+ +L E ++ RE+++++ Q + ++ +
Sbjct: 1242 CKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRW---QQRDRHFPEEEQ 1298
Query: 175 MLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTEL 234
+ R ++EA++ +R+++E+ Q L EE+ + Q+ + + L + + + E
Sbjct: 1299 LEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQER 1358
Query: 235 QT---HPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPA 291
EL G E Q L + + + + +R + R + L D
Sbjct: 1359 DRKFREEELRHQEQGRKFLEEEQRLRRQERERK----FLKEEQQLRCQEREQQLRQDRDR 1414
Query: 292 PSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEED 351
+EE+ + + + EEE++ E E + + E Q Q + EE+
Sbjct: 1415 KF-------REEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEE 1467
Query: 352 KMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 395
++ E+ Q QE KF E E+ L+ E + EQE+
Sbjct: 1468 QLLQEREEQQLH---RQERDRKFLEEEQQLRRQERDRKFREQEL 1508
Score = 41.6 bits (96), Expect = 0.002
Identities = 62/283 (21%), Positives = 117/283 (41%), Gaps = 34/283 (12%)
Query: 122 KERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKE 181
+ER QQ E R F W+ EEK ++ + + + L +Q E +E
Sbjct: 751 EERAHRQQQEEEQRRDFT--------WQWQAEEKSERGRQRLSARPPLREQRERQLRAEE 802
Query: 182 EAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPE-L 240
++ +R E+ +K EQ + ++E+EL F E ++ + +LQ + L
Sbjct: 803 RQQREQRFLPEEEEK---EQRRRQRREREKELQ---FLEEEEQLQRRERAQQLQEEEDGL 856
Query: 241 DTDGDGALSEAEAQAL-----LSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAP 295
D + S+ + + L + + + Y + A++++ R E L
Sbjct: 857 QEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAK--PALQEQLRKEQ---QLLQEEEE 911
Query: 296 DLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEE-EEEDSEVQGEQPKPASPAEEDKMP 354
+L + E+ E+E + EEE+ + EEE+ E+ E + Q + ++ K+
Sbjct: 912 ELQREEREK----RRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
Query: 355 PYDEQ---TQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 394
+EQ + QE K+ E E L+ EE + E+E
Sbjct: 968 QKEEQLLGEEPEKRRRQEREKKYRE-EEELQQEEEQLLREERE 1009
Score = 41.6 bits (96), Expect = 0.002
Identities = 73/308 (23%), Positives = 122/308 (39%), Gaps = 37/308 (12%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAR----EEKQKKLIELQAGKKSLEDQ 172
+EK +E E LQQ E ++L E+ +K R E + +K ELQ ++ L +
Sbjct: 986 REKKYREEEELQQEEE---------QLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE 1036
Query: 173 VEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQ--QEQELAADAFKELDDDMDGTVS 230
R ++E E+ RE +E Q+ EEQL + + + QEL KE + +
Sbjct: 1037 EREKRRLQER-ERQYREEEELQQE--EEQLLGEERETRRRQELERQYRKEEELQQEEEQL 1093
Query: 231 VTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLP 290
+ E PE + E + L + Q R + +YR E
Sbjct: 1094 LRE---EPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEE 1150
Query: 291 APSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEE----------EDSEVQGE 340
+ EP++ + EEEE ++EEE+ EE+E+ E+ E+Q +
Sbjct: 1151 EQLLRE--EPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208
Query: 341 QPKPASPAEED----KMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEIS 396
+ K E+ K E+ A D + + E R L+D + R +Q++
Sbjct: 1209 KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQ 1268
Query: 397 FDFGPNGE 404
G E
Sbjct: 1269 HLLGEQQE 1276
Score = 40.8 bits (94), Expect = 0.003
Identities = 53/282 (18%), Positives = 113/282 (40%), Gaps = 11/282 (3%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
+++ R E Q E +E R + E+ + REE+++K + +K E++ +
Sbjct: 1287 QQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQ 1346
Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAAD--AFKELDDDMDGTVSVTEL 234
++ + ER+ K + ++L ++ ++EQ L K L ++ E
Sbjct: 1347 EREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQ 1406
Query: 235 QTHPELD---TDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPA 291
Q + D + + LS E + Q +R + + R E
Sbjct: 1407 QLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE---RHRKF 1463
Query: 292 PSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEED 351
L + +EEQ + + + EEE++ E + + + E++ ++P+ EE
Sbjct: 1464 REEEQLLQEREEQ-QLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQ 1522
Query: 352 KMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 393
++ Q + F+ Q+ R + E ++ +D + R EQ
Sbjct: 1523 QLHRQQRQ-RKFLQEEQQLRRQ-ERGQQRRQDRDRKFREEEQ 1562
Score = 40.8 bits (94), Expect = 0.003
Identities = 64/297 (21%), Positives = 114/297 (38%), Gaps = 46/297 (15%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLI--ELQAGKKSLEDQVE 174
+E+ RK RE E R + +K L E+ + R+E+++K + E Q + E Q+
Sbjct: 1356 QERDRKFRE------EELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLR 1409
Query: 175 MLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTEL 234
R K E+ + +E+ +K EE+ + ++E++ F E + +
Sbjct: 1410 QDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERK-----FLEEEQQLR-------- 1456
Query: 235 QTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRD-KYRSEALPTDLPAPS 293
Q + + L E E Q L + ++ RD K+R + L + P
Sbjct: 1457 QERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERK 1516
Query: 294 APDLTEPKEEQPPVPSSPTEE---------------------EEEEEEEEEEEAEEEEEE 332
+ + Q EE EEE+ +E EE + +E
Sbjct: 1517 FLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQE 1576
Query: 333 EDSEVQGEQPKPASPAEEDKMPPYDEQ---TQAFIDAAQEARNKFEEAERSLKDMEE 386
D + + E+ K +E K ++Q + QE KF E E+ L++ EE
Sbjct: 1577 RDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREE 1633
Score = 38.9 bits (89), Expect = 0.012
Identities = 59/265 (22%), Positives = 108/265 (40%), Gaps = 42/265 (15%)
Query: 145 IEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAA 204
+++ K+AR + ++ L++ ++ EDQ ++ E+P + +++ Q+ E +LA
Sbjct: 95 LDEEKRARCDGKESLLQ---DRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQ-ERELAE 150
Query: 205 AKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQT- 263
+ Q E++ + D + E Q E + E + Q+ +T+
Sbjct: 151 GEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAE------EEQLQSCKGHETEEF 204
Query: 264 -DATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEE-- 320
D R +R K R E K++Q +EEEE+E
Sbjct: 205 PDEEQLRRRELLELRRKGREE-----------------KQQQRRERQDRVFQEEEEKEWR 247
Query: 321 -------EEEEEAEEEEEEEDSEVQ--GEQPKPASPAEEDKMPPYDEQTQAFIDAAQEAR 371
+EEE+ +EEE + E+Q EQ + E + +EQ Q + Q+ R
Sbjct: 248 KRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLR 307
Query: 372 NKFEEAERSLKD--MEESIRNLEQE 394
K EE R ++ E+ R +QE
Sbjct: 308 RKQEEERREQQEERREQQERREQQE 332
Score = 37.0 bits (84), Expect = 0.044
Identities = 52/268 (19%), Positives = 109/268 (40%), Gaps = 30/268 (11%)
Query: 141 KKILIEDWKKAREEKQ----KKLIELQAGKKSLEDQVEMLRTV---KEEAEKPEREAKEQ 193
K+ L++D ++ ++++ + +E + G++ + + E R + +E++EK ER +
Sbjct: 106 KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRD 165
Query: 194 HQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEA 253
Q+ EE + QE+E + +++ + E + P+ + L E
Sbjct: 166 RQRRDEELWRQRQEWQERE-----ERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRR 220
Query: 254 QALLSGDTQTDATSFYDRVWAAIRDK---YRSEALPTDLPAPSAPDLTEPKEEQPPVPSS 310
+ + Q DRV+ +K R L + E +E+ P
Sbjct: 221 KG--REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKE---------EEKLQEEEPQRQR 269
Query: 311 PTEEEEEE----EEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDA 366
+EEEE+ E +E +EEE++ ++ EQ EE + + + Q
Sbjct: 270 ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE 329
Query: 367 AQEARNKFEEAERSLKDMEESIRNLEQE 394
QE R + + + E+ +R ++E
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEE 357
Score = 35.4 bits (80), Expect = 0.13
Identities = 63/308 (20%), Positives = 117/308 (37%), Gaps = 29/308 (9%)
Query: 113 ENTCKEKGRKERESLQQMAEVTREG-FRLKKILIEDWKKAREEKQKKLIELQAGKKSLED 171
E +E+ + + L++ ++ RE R ++ L + + RE++ ++ +L+ ++ +
Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428
Query: 172 QVEMLRTVKEEAEKPEREAK--EQHQKLW------------EEQLAAAKAQQEQELAADA 217
Q E K E E+ E+ K ++ ++ W E + K QE+E
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488
Query: 218 FKELDDDMDGTVSVTELQTHPELDTDGDGALSEAE----------AQALLSGDTQTDATS 267
K +++ E Q E + + L E ++ L + +
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ 548
Query: 268 FYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAE 327
R ++ R E L + +EE+ +EE E+ + EE E
Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVE 608
Query: 328 EEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEES 387
E+EE E ++ K P EE + + Q Q R + E E+ LK EE
Sbjct: 609 RLEQEERRE---QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEE 665
Query: 388 IRNLEQEI 395
R LEQ +
Sbjct: 666 ER-LEQRL 672
Score = 33.9 bits (76), Expect = 0.37
Identities = 27/121 (22%), Positives = 52/121 (42%), Gaps = 1/121 (0%)
Query: 278 DKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEV 337
D+ R E L + ++EQ + E+ E++E E+ + + +EE +
Sbjct: 118 DQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQR 177
Query: 338 QGEQPKPASPAEEDKMPP-YDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEIS 396
Q Q + AEE+++ +T+ F D Q R + E R ++ ++ R Q+
Sbjct: 178 QEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRV 237
Query: 397 F 397
F
Sbjct: 238 F 238
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 57.8 bits (138), Expect = 2e-08
Identities = 60/258 (23%), Positives = 118/258 (45%), Gaps = 19/258 (7%)
Query: 140 LKKILIEDWKKAREEKQKKLIE-LQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLW 198
+++ +ED K EE + E L K + + + + EAE+ E AK+ K
Sbjct: 457 IEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKAT 516
Query: 199 EEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLS 258
++ + ++E+E + +E +++ +G S E ++ +G+ SE E
Sbjct: 517 APEVKEEEGEKEEE---EGQEEEEEEDEGAKS----DQAEEGGSEKEGS-SEKEEGEQEE 568
Query: 259 GDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEE 318
G+T+ +A + + +SE + T + + +P++ + PVP SP EE+ +
Sbjct: 569 GETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKS 628
Query: 319 ---EEEEEEEAEEEEEEEDSEVQGEQPKPASPAEE-DKMP----PYDEQTQAFI--DAAQ 368
+ EE+ + + E +G+ P P SP EE K P P +E+ ++ + +
Sbjct: 629 PVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVE 688
Query: 369 EARNKFEEAERSLKDMEE 386
EA++K E + K+ EE
Sbjct: 689 EAKSKAEVGKGEQKEEEE 706
Score = 53.5 bits (127), Expect = 5e-07
Identities = 70/313 (22%), Positives = 125/313 (39%), Gaps = 61/313 (19%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILI---------EDWKKAREEKQKKLIELQAGKK 167
KE+ ++ E ++ E E KK + E+ +K EE Q++ E G K
Sbjct: 485 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAK 544
Query: 168 SLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDG 227
S DQ E + KE + + E +E+ + E + A+A++E+++ +
Sbjct: 545 S--DQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS---------- 592
Query: 228 TVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPT 287
E+ T EL D E + + S + + + +K +S +
Sbjct: 593 ----EEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPK--SPVEEKGKSPVPKS 646
Query: 288 DL------PAPSAPDLTEPKEEQP------------PVPSSPTEEEE--------EEEEE 321
+ P P +P E K + P PVP SP EE + E++EE
Sbjct: 647 PVEEKGKSPVPKSP--VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEE 704
Query: 322 EEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSL 381
EE+E +E +EE E + E+PK ++ + P +E + + + E
Sbjct: 705 EEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLE------ 758
Query: 382 KDMEESIRNLEQE 394
K+ +E + L+QE
Sbjct: 759 KETKEEGKPLQQE 771
Score = 51.6 bits (122), Expect = 2e-06
Identities = 64/305 (20%), Positives = 122/305 (40%), Gaps = 35/305 (11%)
Query: 127 LQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEM--------LRT 178
L + AE +E R K I ++++ + K +L ++ K+SLE Q+ L +
Sbjct: 299 LTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSS 358
Query: 179 VKEEAEKPEREAK------EQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTV--S 230
++ ++ E E + +H + +++ L A + A E ++ T S
Sbjct: 359 YQDTIQQLENELRGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFAGS 418
Query: 231 VT-ELQTH-PELDTDGDGALSEAEA----------QALLSGDTQTDATSFYDRVWAAIRD 278
+T L TH P + + EA + ++ D S + AI +
Sbjct: 419 ITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITE 478
Query: 279 KY-------RSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEE 331
+ + EA P A + ++ P ++P +EEE E+EEEE EEEEE
Sbjct: 479 ELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEE 538
Query: 332 EEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNL 391
E++ + + S E EQ + +A E + E+ +++ E +
Sbjct: 539 EDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATK 598
Query: 392 EQEIS 396
E+ ++
Sbjct: 599 EELVA 603
Score = 42.0 bits (97), Expect = 0.001
Identities = 44/151 (29%), Positives = 67/151 (44%), Gaps = 14/151 (9%)
Query: 250 EAEAQALLSGDTQTDATSFYDRVWAAIRDKYRS-EALPTDLPAPSAPDLTEPKEEQPPVP 308
++E + L+ T+ A S + A +K EA ++ A +P K P V
Sbjct: 466 KSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSP----VKATAPEVK 521
Query: 309 SSPTEEEEEE-EEEEEEEAE----EEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAF 363
E+EEEE +EEEEEE E ++ EE SE +G K EE + E +A
Sbjct: 522 EEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEA- 580
Query: 364 IDAAQEARNKFEEAERSLKDMEESIRNLEQE 394
+A +E K EE + EE + + + E
Sbjct: 581 -EAKEE--KKVEEKSEEVATKEELVADAKVE 608
Score = 41.6 bits (96), Expect = 0.002
Identities = 41/198 (20%), Positives = 80/198 (40%), Gaps = 16/198 (8%)
Query: 178 TVKEEAEKPEREA---KEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTEL 234
T+ + +KP+ EA K QH K EE + K + E+ +A + +++ ++ +
Sbjct: 431 TISSKIQKPKVEAPKLKVQH-KFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKK 489
Query: 235 QTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSA 294
+ E + + + +E E A + A + ++ + E D A
Sbjct: 490 EAAEEKEEEPE---AEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGA--- 543
Query: 295 PDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMP 354
K +Q S E E+EE E+EE E E E E E + ++ K E+
Sbjct: 544 ------KSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVAT 597
Query: 355 PYDEQTQAFIDAAQEARN 372
+ A ++ ++A++
Sbjct: 598 KEELVADAKVEKPEKAKS 615
Score = 36.6 bits (83), Expect = 0.058
Identities = 57/267 (21%), Positives = 109/267 (40%), Gaps = 42/267 (15%)
Query: 146 EDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKL-------- 197
E+W K R K + + E E +R+ KEE + R+ + + +L
Sbjct: 289 EEWFKCRYAKLTE---------AAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKE 339
Query: 198 -WEEQLAAAKAQQEQELAA--DAFKELDDDMDGTV--SVTELQTHPELDTDGDGALSEAE 252
E QL+ + + +L++ D ++L++++ GT L+ + +L E
Sbjct: 340 SLERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQDLLNVKMALDIEIA 399
Query: 253 AQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPS--APDLTEPKEEQPPVPSS 310
A L +T ++F + + + + + P AP L K + V
Sbjct: 400 AYRKLLEGEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPKL---KVQHKFVEEI 456
Query: 311 PTEEEEEEEEEEEEEA-----------EEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQ 359
E + E+E+ E EEA +EE++E +E + E+P+ AEE+++
Sbjct: 457 IEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPE----AEEEEVAAKKSP 512
Query: 360 TQAFIDAAQEARNKFEEAERSLKDMEE 386
+A +E + EE E ++ EE
Sbjct: 513 VKATAPEVKEEEGEKEEEEGQEEEEEE 539
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 57.8 bits (138), Expect = 2e-08
Identities = 63/267 (23%), Positives = 121/267 (45%), Gaps = 37/267 (13%)
Query: 140 LKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWE 199
+++ +ED K EE + E E+ ++KEE +K E KE+ + E
Sbjct: 81 IEETKVEDEKSEMEEALTAITE------------ELAVSMKEE-KKEAAEEKEEEPEAEE 127
Query: 200 EQLAAAKA----------QQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALS 249
E++AA K+ ++E E + +E +++ D + + E ++ +G+ S
Sbjct: 128 EEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE---EGGSEKEGS-S 183
Query: 250 EAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPS 309
E E G+T+ +A + + +SE + T + + +P++ + PVP
Sbjct: 184 EKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPK 243
Query: 310 SPTEEEEEE---EEEEEEEAEEEEEEEDSEVQGEQPKPASPAEE-DKMP----PYDEQTQ 361
SP EE+ + + EE+ + + E +G+ P P SP EE K P P +E+ +
Sbjct: 244 SPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAK 303
Query: 362 AFI--DAAQEARNKFEEAERSLKDMEE 386
+ + +EA++K E + K+ EE
Sbjct: 304 SPVPKSPVEEAKSKAEVGKGEQKEEEE 330
Score = 53.5 bits (127), Expect = 5e-07
Identities = 70/313 (22%), Positives = 125/313 (39%), Gaps = 61/313 (19%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILI---------EDWKKAREEKQKKLIELQAGKK 167
KE+ ++ E ++ E E KK + E+ +K EE Q++ E G K
Sbjct: 109 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAK 168
Query: 168 SLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDG 227
S DQ E + KE + + E +E+ + E + A+A++E+++ +
Sbjct: 169 S--DQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS---------- 216
Query: 228 TVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPT 287
E+ T EL D E + + S + + + +K +S +
Sbjct: 217 ----EEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPK--SPVEEKGKSPVPKS 270
Query: 288 DL------PAPSAPDLTEPKEEQP------------PVPSSPTEEEE--------EEEEE 321
+ P P +P E K + P PVP SP EE + E++EE
Sbjct: 271 PVEEKGKSPVPKSP--VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEE 328
Query: 322 EEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSL 381
EE+E +E +EE E + E+PK ++ + P +E + + + E
Sbjct: 329 EEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLE------ 382
Query: 382 KDMEESIRNLEQE 394
K+ +E + L+QE
Sbjct: 383 KETKEEGKPLQQE 395
Score = 48.5 bits (114), Expect = 1e-05
Identities = 29/116 (25%), Positives = 52/116 (44%)
Query: 281 RSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGE 340
+ EA P A + ++ P ++P +EEE E+EEEE EEEEEE++ +
Sbjct: 112 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQ 171
Query: 341 QPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEIS 396
+ S E EQ + +A E + E+ +++ E + E+ ++
Sbjct: 172 AEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVA 227
Score = 42.0 bits (97), Expect = 0.001
Identities = 44/151 (29%), Positives = 67/151 (44%), Gaps = 14/151 (9%)
Query: 250 EAEAQALLSGDTQTDATSFYDRVWAAIRDKYRS-EALPTDLPAPSAPDLTEPKEEQPPVP 308
++E + L+ T+ A S + A +K EA ++ A +P K P V
Sbjct: 90 KSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSP----VKATAPEVK 145
Query: 309 SSPTEEEEEE-EEEEEEEAE----EEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAF 363
E+EEEE +EEEEEE E ++ EE SE +G K EE + E +A
Sbjct: 146 EEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEA- 204
Query: 364 IDAAQEARNKFEEAERSLKDMEESIRNLEQE 394
+A +E K EE + EE + + + E
Sbjct: 205 -EAKEE--KKVEEKSEEVATKEELVADAKVE 232
Score = 41.6 bits (96), Expect = 0.002
Identities = 41/198 (20%), Positives = 80/198 (40%), Gaps = 16/198 (8%)
Query: 178 TVKEEAEKPEREA---KEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTEL 234
T+ + +KP+ EA K QH K EE + K + E+ +A + +++ ++ +
Sbjct: 55 TISSKIQKPKVEAPKLKVQH-KFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKK 113
Query: 235 QTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSA 294
+ E + + + +E E A + A + ++ + E D A
Sbjct: 114 EAAEEKEEEPE---AEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGA--- 167
Query: 295 PDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMP 354
K +Q S E E+EE E+EE E E E E E + ++ K E+
Sbjct: 168 ------KSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVAT 221
Query: 355 PYDEQTQAFIDAAQEARN 372
+ A ++ ++A++
Sbjct: 222 KEELVADAKVEKPEKAKS 239
Score = 30.0 bits (66), Expect = 5.4
Identities = 29/115 (25%), Positives = 50/115 (43%), Gaps = 22/115 (19%)
Query: 290 PAPSAPDLTEPKEEQPPVPSSPTEEEE-------EEEEEEEEEA-----------EEEEE 331
P + + +PK E P + EE E+E+ E EEA +EE+
Sbjct: 53 PITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEK 112
Query: 332 EEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEE 386
+E +E + E+P+ AEE+++ +A +E + EE E ++ EE
Sbjct: 113 KEAAEEKEEEPE----AEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEE 163
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 57.4 bits (137), Expect = 3e-08
Identities = 78/304 (25%), Positives = 124/304 (40%), Gaps = 30/304 (9%)
Query: 101 DGTDEYNSGVICENTCKEKGRKERESLQQM-AEV-TREGFRLKKILIEDWKKAREEKQKK 158
+G + S VI +E+ + E E ++ + EV T+E + ED + E + +
Sbjct: 1951 EGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQ 2010
Query: 159 LIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQE-LAADA 217
E +A +S D VE +P+ E +E + E Q AQ E + + A
Sbjct: 2011 EAEEEAQPES--DGVEA---------QPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPE 2059
Query: 218 FKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIR 277
+E + +G V E + HPE + D D +E EAQ G +A +
Sbjct: 2060 AEEEAQEAEGEVQEAEGEAHPESE-DVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEA 2118
Query: 278 DKYRSEALPTD--LPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDS 335
+ EA P + AP A +P+ E + E + E E E +EAEEE + E
Sbjct: 2119 PETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELE 2178
Query: 336 EVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFE-----EAERSLKDMEESIRN 390
V+ +P E + P E +A +A EA+ + E EAE + E +
Sbjct: 2179 GVE-------APEAEGEAQPESEGIEA-PEAEGEAQPELEGVEAPEAEEEAQPEPEGVET 2230
Query: 391 LEQE 394
E E
Sbjct: 2231 PEAE 2234
Score = 56.2 bits (134), Expect = 7e-08
Identities = 62/229 (27%), Positives = 90/229 (39%), Gaps = 24/229 (10%)
Query: 181 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL 240
E+ E PE E + Q + E A Q + A+A + + T SV L+T E
Sbjct: 1872 EDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGED 1931
Query: 241 DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRS----EALPTDLPAPSAPD 296
+ + +GA ++ +A + QT S A + EAL ++ A
Sbjct: 1932 EPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEG 1991
Query: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEE----------EEEEDSEVQGEQPKPAS 346
+P+ E P E E E +E EEEA+ E E EE EV+GE K
Sbjct: 1992 EAQPESEDVEAP-----EAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQK--- 2043
Query: 347 PAEEDKMPPYD-EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 394
E D P D + + AQEA + +EAE E + E E
Sbjct: 2044 -TEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAE 2091
Score = 47.0 bits (110), Expect = 4e-05
Identities = 52/238 (21%), Positives = 101/238 (42%), Gaps = 16/238 (6%)
Query: 150 KAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQ 209
+A +E Q + ++A + ED+ E +EAE+ +EA+ Q Q E + + +A++
Sbjct: 1910 EAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPE-SEVIESQEAEE 1968
Query: 210 EQELAADAFKELDDDMDGTVSVTELQTHPE--LDTDGDGALSEAEAQALLSGDTQTDATS 267
E + ++ + L+ +++ + E Q E + +G + EAE +A ++D
Sbjct: 1969 EAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEA----QPESDGVE 2024
Query: 268 FYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAE 327
+ + E T+ A D E E EEE +E E E +EAE
Sbjct: 2025 AQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPE---------AEEEAQEAEGEVQEAE 2075
Query: 328 EEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDME 385
E E +V ++ + + E + + + + +A EA EA+ + +E
Sbjct: 2076 GEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIE 2133
Score = 42.7 bits (99), Expect = 8e-04
Identities = 52/220 (23%), Positives = 88/220 (40%), Gaps = 9/220 (4%)
Query: 146 EDWKKAREEKQKKLIELQAGKKSLE--DQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLA 203
E+ ++ E QK + Q +E + E + + E ++ E EA + + + + Q A
Sbjct: 2032 EEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDV-DAQEA 2090
Query: 204 AAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDG-DGALSEAEAQALLSGDTQ 262
+AQ E E E + + E + + +++G + +E EAQ G
Sbjct: 2091 EGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEA 2150
Query: 263 TDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEE 322
DA I + E +L AP+ + + +P E E + E E
Sbjct: 2151 QDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELE 2210
Query: 323 EEEAEEEEEEEDSEVQG-EQPKPASPAEEDKMPPYDEQTQ 361
EA E EEE E +G E P+ AE + P + +TQ
Sbjct: 2211 GVEAPEAEEEAQPEPEGVETPE----AEGEAQPESEGETQ 2246
Score = 42.4 bits (98), Expect = 0.001
Identities = 49/195 (25%), Positives = 78/195 (40%), Gaps = 21/195 (10%)
Query: 200 EQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSG 259
E + A +A+ E + ++ + + + D + E Q E D + A EA+ + S
Sbjct: 1833 EGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESE-DVEAPEAEGEAQPE---SE 1888
Query: 260 DTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEE 319
D +T W + +EA P A KE QP S E E E+
Sbjct: 1889 DVETPEAE-----WEVQPESEGAEA-------PEAE-----KEAQPETESVEALETEGED 1931
Query: 320 EEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAER 379
E E E AE +E EE ++ Q +P S E + + Q ++ A E + +EAE
Sbjct: 1932 EPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEG 1991
Query: 380 SLKDMEESIRNLEQE 394
+ E + E E
Sbjct: 1992 EAQPESEDVEAPEAE 2006
Score = 40.8 bits (94), Expect = 0.003
Identities = 57/225 (25%), Positives = 90/225 (40%), Gaps = 23/225 (10%)
Query: 150 KAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAE-KPEREAKEQHQKLWEEQLAAA--- 205
+A EE Q+ E+Q + + E + + E E +PE E E + E Q A
Sbjct: 2059 EAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEA 2118
Query: 206 -----KAQQEQE--LAADAFKELDDDMDGTVSVTELQTHPELDTDG-DGALSEAEAQALL 257
+AQ E E A +A E + +G V + + + +++G + +E EAQ L
Sbjct: 2119 PETEGEAQPESEGIEAPEAEGEAQPESEG-VEAQDAEGEAQPESEGIEAQEAEEEAQPEL 2177
Query: 258 SGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEE 317
G +A I +L AP E +EE P P E E
Sbjct: 2178 EGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAP---EAEEEAQPEPEGVETPEAE 2234
Query: 318 EEEEEEEEAEEEEEEEDS------EVQGEQ-PKPASPAEEDKMPP 355
E + E E E + E++ S + Q E+ + +SP ED+ P
Sbjct: 2235 GEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTP 2279
Score = 38.9 bits (89), Expect = 0.012
Identities = 42/165 (25%), Positives = 64/165 (38%), Gaps = 20/165 (12%)
Query: 242 TDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPT--DLPAPSAPDLTE 299
+DG + EA+ G+ Q ++ + EA P D+ AP A +
Sbjct: 1829 SDGAEGIEAPEAE----GEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQ 1884
Query: 300 PKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQ 359
P+ E P + E E + E E EA E E+E E E + ED+ +
Sbjct: 1885 PESEDVETPEA---EWEVQPESEGAEAPEAEKEAQPET--ESVEALETEGEDEPESEGAE 1939
Query: 360 TQAFIDAAQEARN---------KFEEAERSLKDMEESIRNLEQEI 395
Q +AAQEA + +EAE + E + LE E+
Sbjct: 1940 AQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEV 1984
Score = 37.7 bits (86), Expect = 0.026
Identities = 51/221 (23%), Positives = 84/221 (38%), Gaps = 43/221 (19%)
Query: 181 EEAEKPEREAKEQHQKLWEEQLAAAKAQQE------QELAADAFKELDDDMDGTVSVTEL 234
E+ E +R +++ KL E + A ++E + A E + + +G +
Sbjct: 1744 EDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEG------I 1797
Query: 235 QTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSA 294
E G G + +A GD +D +S+ + AP A
Sbjct: 1798 SERGETGGQGSGHEDNLQGEAAAGGD----------------QDPGQSDGAE-GIEAPEA 1840
Query: 295 PDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEED-KM 353
+P+ E P E E + +E E E E E+ E E +GE A P ED +
Sbjct: 1841 EGEAQPESEGVEAP----EAEGDAQEAEGEAQPESEDVEAPEAEGE----AQPESEDVET 1892
Query: 354 PPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 394
P + + Q + A+ EAE+ + ES+ LE E
Sbjct: 1893 PEAEWEVQPESEGAEA-----PEAEKEAQPETESVEALETE 1928
Score = 34.7 bits (78), Expect = 0.22
Identities = 44/204 (21%), Positives = 75/204 (36%), Gaps = 23/204 (11%)
Query: 153 EEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQE 212
E++ ++ E Q +LE E TV+EE + E + + + L EE + + + E+
Sbjct: 1273 EDEAERDSEEQRASSNLEQLAE--NTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEG 1330
Query: 213 LAADAFK-ELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDR 271
L + + E + +G E E++ G L E Q +
Sbjct: 1331 LQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQL--------------EE 1376
Query: 272 VWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEE 331
V + EAL L P+ ++ SSP + +E++ +EE
Sbjct: 1377 VKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEE------ 1430
Query: 332 EEDSEVQGEQPKPASPAEEDKMPP 355
E +P PA EE PP
Sbjct: 1431 EAGRASASAEPCPAEGTEEPTEPP 1454
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 57.0 bits (136), Expect = 4e-08
Identities = 56/288 (19%), Positives = 128/288 (44%), Gaps = 17/288 (5%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQ---KKLIELQAGKKSLEDQV 173
+EK R++ E +++ E R R ++++ E +K R +++ +K +++ ++ + ++
Sbjct: 381 EEKIREQEEKIREQEEKMR---RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 437
Query: 174 EMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTE 233
E +R ++E+ + E+ +++ ++ EE++ + +QEQE +E + + + E
Sbjct: 438 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 497
Query: 234 --LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWA------AIRDKYRSEAL 285
+ E + + E + Q Q + + +W +K R +
Sbjct: 498 EKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEE 557
Query: 286 PTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPA 345
D E EQ +EE+ E+EE+ E+EE+ + E ++ +
Sbjct: 558 KMWRQEEKMHDQEEKIREQ---EEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEK 614
Query: 346 SPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 393
+E+KM +E+ Q + + K E E+ +++ EE IR E+
Sbjct: 615 MGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 662
Score = 54.7 bits (130), Expect = 2e-07
Identities = 50/281 (17%), Positives = 117/281 (41%), Gaps = 30/281 (10%)
Query: 122 KERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKE 181
+E E ++ + E ++ I++W++ +E+++K+ E + + + +Q E +R +E
Sbjct: 347 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE---EKIREQEEKMRRQEE 403
Query: 182 EAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELD 241
+ E + + Q + +WE++ + ++ + +EL++ M + E + + +
Sbjct: 404 MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE 463
Query: 242 TDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPK 301
E +A ++W +K R + E
Sbjct: 464 EKIREQEKRQEQEA---------------KMWRQ-EEKIREQEEKIREQEEKMWRQEEKI 507
Query: 302 EEQPPVPSSPTEEEEEEEEEEEEEAEEEEE---------EEDSEVQGEQPKPASPAEEDK 352
EQ + +E+EE +EE+ E+EE E++ +++ ++ K +E+K
Sbjct: 508 HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEK--MWRQEEK 565
Query: 353 MPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 393
M +E+ + + K E E +++ EE IR E+
Sbjct: 566 MHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE 606
Score = 51.2 bits (121), Expect = 2e-06
Identities = 57/302 (18%), Positives = 128/302 (42%), Gaps = 27/302 (8%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWK-KAREEKQKKLIELQAGKKSLEDQVEM 175
+EK R++ E + + E RE L++ + E K + +EEK+++ +++ +K E + +M
Sbjct: 423 EEKMRRQEEMMWEKEEKIRE---LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 479
Query: 176 LRTVKEEAEKPEREAKEQHQKLW--------EEQLAAAKAQQEQE---LAADAFKELDDD 224
R +E+ + E + +EQ +K+W +E++ + +QEQE + +E ++
Sbjct: 480 WRQ-EEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 538
Query: 225 MDGTVSVTELQT-----------HPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVW 273
+ E + E D + + E E + + +
Sbjct: 539 WRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE 598
Query: 274 AAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEE 333
IR++ + + E +E+ +EE+ E+E++ E+EE+
Sbjct: 599 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIR 658
Query: 334 DSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 393
+ E ++ + +E+KM +E+ Q + + K E E L+ EE ++ ++
Sbjct: 659 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Query: 394 EI 395
+
Sbjct: 719 HL 720
Score = 48.1 bits (113), Expect = 2e-05
Identities = 50/253 (19%), Positives = 115/253 (45%), Gaps = 16/253 (6%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
+EK R++ E +++ E + +R ++ + E K EEK+++ E+ ++ + +Q E+
Sbjct: 483 EEKIREQEEKIREQEE---KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 539
Query: 177 RTVKEEAEKPEREAKEQHQKLW--EEQLAAAKA---QQEQELAADAFKELDDDMDGTVSV 231
R KE+ + E + ++Q +K+W EE++ + +QE+++ K + +
Sbjct: 540 RQ-KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE 598
Query: 232 TELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPA 291
+++ E+ + + + E E + + + R IR++ + +
Sbjct: 599 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEE--- 655
Query: 292 PSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEED 351
+ E +E E+EE+ E+EE+ E+EE+ E + + + +E+
Sbjct: 656 ----KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 711
Query: 352 KMPPYDEQTQAFI 364
KM + E +A I
Sbjct: 712 KMQEHQEHLEAAI 724
Score = 37.7 bits (86), Expect = 0.026
Identities = 22/83 (26%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Query: 313 EEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARN 372
EE+ +E EE+ +E EE+ E++ +++ ++ K +E+ M +E+ + + E
Sbjct: 367 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR--QEEMMWEKEEKMRRQEEMMWEKEE 424
Query: 373 KFEEAERSLKDMEESIRNLEQEI 395
K E + + EE IR LE+++
Sbjct: 425 KMRRQEEMMWEKEEKIRELEEKM 447
Score = 32.3 bits (72), Expect = 1.1
Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 313 EEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARN 372
E+EE+ E+EE+ E+EE+ E + + +E+ M +E+ + + E
Sbjct: 379 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 438
Query: 373 KFEEAERSLKDMEESIRNLEQE 394
K E E + + +E IR E++
Sbjct: 439 KIRELEEKMHE-QEKIREQEEK 459
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 56.6 bits (135), Expect = 5e-08
Identities = 60/260 (23%), Positives = 105/260 (40%), Gaps = 38/260 (14%)
Query: 150 KAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQ 209
+AREEK +K +E + LE++ + ++E E+ ERE +E ++L + + KAQ+
Sbjct: 308 QAREEKHQKQLE----RAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQK 363
Query: 210 EQELAADAFKELDDDMDGTVSVTE-LQTHPELDTDGDGALSEAEAQALLSGD-------- 260
E E ELD + E L+ + A+++ A + + +
Sbjct: 364 ELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAE 423
Query: 261 --------------TQTDATSFYDRVWAAIRDKYRS-EALPTDLPAPSAPDLTEPKEEQP 305
+ +AT + + +AA D ++ E L T + AP P P
Sbjct: 424 FTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMSAPPPP--------PP 475
Query: 306 PVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFID 365
P PTE E +E +E EA E E V + + E K +Q QA
Sbjct: 476 PPVIPPTENEHDEHDENNAEASAELSNEG--VMNHRSEEERVTETQKNERVKKQLQALSS 533
Query: 366 AAQEARNKFEEAERSLKDME 385
+AR++ ++ + + E
Sbjct: 534 ELAQARDETKKTQNDVLHAE 553
Score = 30.8 bits (68), Expect = 3.2
Identities = 21/97 (21%), Positives = 44/97 (45%), Gaps = 3/97 (3%)
Query: 301 KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEED---KMPPYD 357
K + V + EE+ +++ E A+ E E++ E+ ++ + +E+ ++ +
Sbjct: 296 KPDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIE 355
Query: 358 EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 394
EQT +E K E ++ K +E LE+E
Sbjct: 356 EQTIKAQKELEEQTRKALELDQERKRAKEEAERLEKE 392
>gi|14249738 N-acetylglucosamine-1-phosphotransferase, gamma subunit
[Homo sapiens]
Length = 305
Score = 56.6 bits (135), Expect = 5e-08
Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 5/105 (4%)
Query: 408 LYSQCYELTTNEYVYRLCPFKLVSQKPKL---GGSPTSLGTWGSWIGPDHDKFSAMKYEQ 464
L +C+ L + Y Y CPF V+Q + LG W W ++ F+ M
Sbjct: 67 LSGKCFSLVESTYKYEFCPFHNVTQHEQTFRWNAYSGILGIWHEW-EIANNTFTGMWMRD 125
Query: 465 GTGCWQGPNRSTTVRLLCGKETMVTSTTEPSRCEYLMELMTPAAC 509
G C + +R + V L CGK + +EPS C Y + TP C
Sbjct: 126 GDAC-RSRSRQSKVELACGKSNRLAHVSEPSTCVYALTFETPLVC 169
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 55.8 bits (133), Expect = 9e-08
Identities = 60/321 (18%), Positives = 127/321 (39%), Gaps = 25/321 (7%)
Query: 122 KERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKE 181
+E E ++ + E ++ I++W++ +E+++K+ E + + + +Q E +R +E
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE---EKIREQEEKMRRQEE 342
Query: 182 EAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELD 241
+ E + + Q + +WE++ + ++ + +EL++ M + E Q +
Sbjct: 343 MMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIRE-QEEKRQE 401
Query: 242 TDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPK 301
+ + + Q + +++ + +R E E
Sbjct: 402 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE---------------EKI 446
Query: 302 EEQPPVPSSPTEEEEEEEEEEEEEAEEEEE-EEDSEVQGEQPKPASPAE-----EDKMPP 355
EQ + +E+EE +EE+ E+EE E EQ K E E+KM
Sbjct: 447 HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHD 506
Query: 356 YDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYEL 415
+E+ + + K E E +++ EE IR E+ + GE + ++
Sbjct: 507 QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKM 566
Query: 416 TTNEYVYRLCPFKLVSQKPKL 436
E R K+ QK K+
Sbjct: 567 RRQEEKIREQEEKIREQKEKI 587
Score = 55.8 bits (133), Expect = 9e-08
Identities = 60/295 (20%), Positives = 129/295 (43%), Gaps = 26/295 (8%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKARE------EKQKKLIELQAGKKSLE 170
+EK R++ E +++ E R R ++++ E +K R EK++K+ L+ + +
Sbjct: 320 EEKIREQEEKIREQEEKMR---RQEEMMWEKEEKMRRQEEMMWEKEEKMRRLE---EMMW 373
Query: 171 DQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVS 230
++ E +R ++E+ + E+ +++ ++ EE++ + +QEQE +E + + +
Sbjct: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433
Query: 231 VTE--LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEAL-PT 287
E + E + + E + Q Q + + +W + E +
Sbjct: 434 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
Query: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEE---------EEDSEVQ 338
+ + +EE+ +EE+ E+EE+ E+EE +E E
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553
Query: 339 GEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 393
GEQ + E++KM +E+ + + +E + K E E + + EE IR E+
Sbjct: 554 GEQEEKMQ--EQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEE 606
Score = 52.8 bits (125), Expect = 8e-07
Identities = 56/288 (19%), Positives = 129/288 (44%), Gaps = 22/288 (7%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWK-KAREEKQKKLIELQAGKKSLEDQVEM 175
+EK R+ E + + E RE L++ + E K + +EEK+++ +++ +K E + +M
Sbjct: 362 EEKMRRLEEMMWEKEEKIRE---LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 418
Query: 176 LRTVKEEAEKPEREAKEQHQKLW--------EEQLAAAKAQQEQELAADAFKELDDDMDG 227
R +E+ + E + +EQ +K+W +E++ + +QEQE +++ + +
Sbjct: 419 WRQ-EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 477
Query: 228 TVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPT 287
++ ++ + + E D + +++W +K R +
Sbjct: 478 WRQKEKMHEQEKIRKQEEKVWRQEEKMH----DQEEKIREQEEKMWRQ-EEKIREQEEKI 532
Query: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASP 347
+ E +EQ E+EE+ +E+E+ +EE+ + E + + K
Sbjct: 533 REQEEKIREQEEMMQEQ----EEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIR 588
Query: 348 AEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 395
+E+K+ +E+ + + QE K E E + + EE ++ E+++
Sbjct: 589 EQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 636
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/254 (18%), Positives = 118/254 (46%), Gaps = 37/254 (14%)
Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRL--KKILIEDWKKAREEKQKKLIELQAGKKSLE 170
E +E+ R+E+E + + E RE + +K + + +K R++++K + ++ +
Sbjct: 450 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEK----VWRQEEKMH 505
Query: 171 DQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVS 230
DQ E +R +E+ + E + +EQ +K+ E++ K ++++E+ + +++ + +
Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQEEKIREQE---EKIREQEEMMQEQEEKMGEQEEKMQE 562
Query: 231 VTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLP 290
+++ E + + + E + + +++W +K R +
Sbjct: 563 QEKMRRQEEKIREQEEKIREQKEKI----------REQEEKIWEQ-EEKIREQE------ 605
Query: 291 APSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEE 350
++ + +EE+ E+EE+ E+EE+ E+EE+ E + + + +E
Sbjct: 606 -----EMMQEQEEKM------WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 654
Query: 351 DKMPPYDEQTQAFI 364
+KM + E +A I
Sbjct: 655 EKMQEHQEHLEAAI 668
Score = 34.7 bits (78), Expect = 0.22
Identities = 54/272 (19%), Positives = 109/272 (40%), Gaps = 33/272 (12%)
Query: 146 EDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTV--------------KEEAEKPEREAK 191
ED +KA + Q+ L ++ LE QV +R + + ++ E EA+
Sbjct: 108 EDEQKASHQHQEAL------RRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEAR 161
Query: 192 EQHQKLWEEQLAAAKAQQEQELAADAFKELD---DDMDGTVSVTELQTHPELDTDGDGAL 248
+ +L + A + +Q A K+ D +++ L+ + TD +
Sbjct: 162 DLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKE 221
Query: 249 SEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEAL-PTDLPAPSAPDLTEPKEEQPPV 307
A+ Q L +++ + V R R++ L P A L + +
Sbjct: 222 KNAKLQEKLQL-VESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 280
Query: 308 PSSPTEEEE------EEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQ 361
+ EE E +++EE+ EE+ +E + ++Q ++ K +E+K+ +E+ +
Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE--QEEKIREQEEKMR 338
Query: 362 AFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 393
+ E K E + + EE +R LE+
Sbjct: 339 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEE 370
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 55.8 bits (133), Expect = 9e-08
Identities = 62/260 (23%), Positives = 110/260 (42%), Gaps = 12/260 (4%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
K++ RKE++ + + E RE R K+ E K RE +++K E+ E + +
Sbjct: 101 KDEKRKEKKHAR-VKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGV 159
Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQT 236
++ E+ ER+ +E+ +K+ E+Q + ++ + A + KE + + E+
Sbjct: 160 CLFRDRLEQLERK-RERERKMREQQKEQREQKERERRAEERRKERE-------ARREVSA 211
Query: 237 HPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPD 296
H + +A + + D +K L +DL S +
Sbjct: 212 HHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSE 271
Query: 297 LTEPKEEQPPVPS---SPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKM 353
E S S EEEEEEEEEEE EE EEE+ E + E+ + S +EE
Sbjct: 272 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE 331
Query: 354 PPYDEQTQAFIDAAQEARNK 373
+E ++ + +E N+
Sbjct: 332 QSAEEVSEEEMSEDEERENE 351
Score = 37.0 bits (84), Expect = 0.044
Identities = 51/247 (20%), Positives = 98/247 (39%), Gaps = 46/247 (18%)
Query: 91 RVNDGVCDCCDGTDEYNSGVICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKK 150
R NDGVC D ++ + K +ER+ +Q E + R ++ E+ +K
Sbjct: 154 RGNDGVCLFRDRLEQ----------LERKRERERKMREQQKEQREQKERERR--AEERRK 201
Query: 151 AREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQE 210
RE +++ + ++ D+V+ + P R +E+ + + + +E
Sbjct: 202 EREARREVSAHHRTMREDYSDKVK----ASHWSRSPPRPPRERFELGDGRKPVKEEKMEE 257
Query: 211 QELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYD 270
++L +D L D +S +E +T S AE+ + SG +
Sbjct: 258 RDLLSD----LQD-----ISDSERKT------------SSAESSSAESGSGSEEEEE--- 293
Query: 271 RVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEE 330
++ E T + + E +EE+ S E+ EE EEE +E+EE
Sbjct: 294 ------EEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 347
Query: 331 EEEDSEV 337
E ++ +
Sbjct: 348 RENENHL 354
Score = 36.6 bits (83), Expect = 0.058
Identities = 44/180 (24%), Positives = 75/180 (41%), Gaps = 22/180 (12%)
Query: 117 KEKGRKERE---SLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQV 173
KE+ +ER+ LQ +++ R+ + E + EE++++ E + G S E +
Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE- 309
Query: 174 EMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTE 233
EE E+ E E +E E +A+ E+E++ D +E ++
Sbjct: 310 -------EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENEN---------H 353
Query: 234 LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRV--WAAIRDKYRSEALPTDLPA 291
L PE D D SE + + G Q+ A + D V A+ + LP LPA
Sbjct: 354 LLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPA 413
Score = 30.0 bits (66), Expect = 5.4
Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%)
Query: 51 VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110
+ +DY D S + P G KP+ D + D D +D
Sbjct: 216 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 275
Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170
E++ E G E ++ E EG ++ E+ ++ EE++ +A ++S E
Sbjct: 276 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 335
Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194
+ E EE + E E H
Sbjct: 336 EVSE------EEMSEDEERENENH 353
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 55.5 bits (132), Expect = 1e-07
Identities = 64/256 (25%), Positives = 108/256 (42%), Gaps = 37/256 (14%)
Query: 121 RKERESLQQMAEVTR--EGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRT 178
R E+++Q AE+ R + FR + +ED ++++ K + EL+ K++LE QVE ++T
Sbjct: 1483 RALEEAMEQKAELERLNKQFRTE---MEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKT 1539
Query: 179 VKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQEL-----------------AADAFKEL 221
EE E E +A E + E L A KAQ E++L + EL
Sbjct: 1540 QLEELE-DELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAEL 1598
Query: 222 DDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYR 281
+D+ + E+D L + EA + + +A ++ A ++D R
Sbjct: 1599 EDERKQRSMAVAARKKLEMD------LKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMR 1652
Query: 282 SEALPTDLPAPSAPDLTEPKEEQPPVPSSPTE-----EEEEEEEEEEEEAEEEEEEEDSE 336
D A L + KE + + S E EE E + +A++E +E E
Sbjct: 1653 E---LDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADE 1709
Query: 337 VQGEQPKPASPAEEDK 352
+ K A EE +
Sbjct: 1710 IANSSGKGALALEEKR 1725
Score = 46.6 bits (109), Expect = 6e-05
Identities = 73/297 (24%), Positives = 127/297 (42%), Gaps = 33/297 (11%)
Query: 125 ESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAE 184
E+ + A +T + L++I D + EE++++ LQA KK ++ ++ L EE E
Sbjct: 898 EAEELRARLTAKKQELEEIC-HDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 956
Query: 185 KPERE-------AKEQHQKLWEEQLAA----AKAQQEQELAADAFKE----LDDDMDGTV 229
++ + + +KL EEQ+ K +E++L D E L ++ + +
Sbjct: 957 SARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSK 1016
Query: 230 SVTELQT-HPELDTDGDGALSEAEAQ--------ALLSGDTQTDATSFYDRVWAAIRD-K 279
S+ +L+ H + TD + L E Q L GD+ TD + + A I + K
Sbjct: 1017 SLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDS-TDLSDQIAELQAQIAELK 1075
Query: 280 YRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQG 339
+ +L A A EE+ + ++ E E + E E+ E E S +
Sbjct: 1076 MQLAKKEEELQAALA-----RVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKA 1130
Query: 340 EQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSL-KDMEESIRNLEQEI 395
E+ K E + + E T A QE R+K E+ L K +EE + E +I
Sbjct: 1131 EKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQI 1187
Score = 42.0 bits (97), Expect = 0.001
Identities = 61/301 (20%), Positives = 127/301 (42%), Gaps = 33/301 (10%)
Query: 114 NTCKEKGRKERESLQ-QMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQ 172
N +++ K+ LQ QM + RE ++D + +REE + E + KS+E +
Sbjct: 1630 NKNRDEAIKQLRKLQAQMKDCMRE--------LDDTRASREEILAQAKENEKKLKSMEAE 1681
Query: 173 VEMLRTVKEEAEKPEREAKEQHQKLWEE----------------QLAAAKAQQEQELAAD 216
+ L+ AE+ +R+A+++ +L +E +L A AQ E+EL +
Sbjct: 1682 MIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEE 1741
Query: 217 AFK-ELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAA 275
EL +D ++ Q + +L+ + A A+ L + + +
Sbjct: 1742 QGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQE-MEGT 1800
Query: 276 IRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDS 335
++ KY++ T L A A + E ++ + E++ ++ + ++E ++
Sbjct: 1801 VKSKYKASI--TALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNA 1858
Query: 336 EVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 395
E +Q AS ++ Q + + AQ A + +R L+D E+ + +E+
Sbjct: 1859 EQYKDQADKAST----RLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREV 1914
Query: 396 S 396
S
Sbjct: 1915 S 1915
Score = 40.4 bits (93), Expect = 0.004
Identities = 65/320 (20%), Positives = 134/320 (41%), Gaps = 46/320 (14%)
Query: 117 KEKGRKERESLQQMAEVTREGFRLKKIL-IEDWKKAREEKQKKLI--ELQAGKKSLEDQV 173
+E+ ++ +L+++ E+ + L++ L E + + EKQK+ + EL+A K LED +
Sbjct: 1093 EEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTL 1152
Query: 174 EMLRTVKEEAEKPEREAKEQHQKLWEE-QLAAAKAQQEQELAADAFKELDDDMDGTVSVT 232
+ +E K E+E + L EE + A+ Q+ ++ + A +EL + ++ T V
Sbjct: 1153 DSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVK 1212
Query: 233 ELQTHPELDTDGDGALSEAEAQALLSGDTQTDAT---------------SFYDRVWAAIR 277
+ + + E + LL G ++ + +RV +
Sbjct: 1213 ANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELA 1272
Query: 278 DKY-------------------RSEALPTDLPAPSAP--DLTEPKEEQPPVPSSPTEEEE 316
DK +S L D A + D E +E+ S + + +
Sbjct: 1273 DKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLK 1332
Query: 317 EEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEE 376
+ E+E+ E+ EEEE+++ E+ A+ M E + ++ A+E + K +
Sbjct: 1333 QVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQ- 1391
Query: 377 AERSLKDMEESIRNLEQEIS 396
KD+E + E++++
Sbjct: 1392 -----KDLEGLSQRHEEKVA 1406
Score = 33.9 bits (76), Expect = 0.37
Identities = 55/288 (19%), Positives = 118/288 (40%), Gaps = 16/288 (5%)
Query: 121 RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRT-- 178
+K+ E E E R + +E + EEK +L+ K L+ +++ L
Sbjct: 1370 KKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDL 1429
Query: 179 --VKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQT 236
++ A E++ K+ Q L EE+ +AK +E++ A +E + E
Sbjct: 1430 DHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAM 1489
Query: 237 HPELDTDGDGALSEAEAQALLSG-DTQTDATSFYDRVWAAIRD-----KYRSEALPTDLP 290
+ + + E + L+S D + ++ A+ K + E L +L
Sbjct: 1490 EQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQ 1549
Query: 291 APSAPDLTEPKEEQPPVP--SSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPA 348
A L Q + +E+ EE++++ + E ++E++ E+ + +
Sbjct: 1550 ATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAV 1609
Query: 349 EEDKMPPYD-EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 395
K D + +A ID+A + R +EA + L+ ++ +++ +E+
Sbjct: 1610 AARKKLEMDLKDLEAHIDSANKNR---DEAIKQLRKLQAQMKDCMREL 1654
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 55.5 bits (132), Expect = 1e-07
Identities = 29/56 (51%), Positives = 35/56 (62%)
Query: 296 DLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEED 351
D E +EE+ EEEEEEEEEEEEE EEEEEEE+ E + E+ P +ED
Sbjct: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQED 316
Score = 53.1 bits (126), Expect = 6e-07
Identities = 26/62 (41%), Positives = 39/62 (62%)
Query: 298 TEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYD 357
+E +Q + S E+EEEEEEEEEEE +EEEEEE+ E + E+ + EE++ +
Sbjct: 245 SEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304
Query: 358 EQ 359
E+
Sbjct: 305 EE 306
Score = 53.1 bits (126), Expect = 6e-07
Identities = 28/58 (48%), Positives = 36/58 (62%)
Query: 313 EEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEA 370
EEEEEE+EEEEEE EEEEEEE+ E + E+ + EE+ P Q +AQ+A
Sbjct: 268 EEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKA 325
Score = 52.8 bits (125), Expect = 8e-07
Identities = 26/68 (38%), Positives = 41/68 (60%)
Query: 313 EEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARN 372
EEE+EEEEEEEEE EE+EEEE+ E + E+ + EE++ +E+ +A D +
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDT 317
Query: 373 KFEEAERS 380
A+++
Sbjct: 318 SHTSAQKA 325
Score = 52.0 bits (123), Expect = 1e-06
Identities = 29/75 (38%), Positives = 41/75 (54%)
Query: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASP 347
DL S D + + S EE+EEEEEEEEEE E+EEEEE+ E + E+ +
Sbjct: 234 DLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEE 293
Query: 348 AEEDKMPPYDEQTQA 362
EE++ +E+ A
Sbjct: 294 EEEEEEEEEEEEEAA 308
Score = 40.4 bits (93), Expect = 0.004
Identities = 36/133 (27%), Positives = 61/133 (45%), Gaps = 12/133 (9%)
Query: 113 ENTCKEKGRK----ERESLQQMAEVTREGFR-LKKILIEDWKKAREEKQKKLIELQAGKK 167
E E+G K + E +++ EVT E + L +ED KQK ++ + +
Sbjct: 203 EGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDE 262
Query: 168 SLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDG 227
E++ E +EE E+ E E +E+ ++ EE+ + ++E+E A D + D
Sbjct: 263 EEEEEEEEEEEDEEEEEEEEEEEEEEEEE-EEEEEEEEEEEEEEEAAPDVIFQED----- 316
Query: 228 TVSVTELQTHPEL 240
S T Q PEL
Sbjct: 317 -TSHTSAQKAPEL 328
Score = 38.9 bits (89), Expect = 0.012
Identities = 22/56 (39%), Positives = 27/56 (48%)
Query: 299 EPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMP 354
E +EE+ EEEEEEEEEEEE A + +ED+ Q P E P
Sbjct: 281 EEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSP 336
Score = 33.1 bits (74), Expect = 0.64
Identities = 17/71 (23%), Positives = 34/71 (47%)
Query: 314 EEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNK 373
E+ EE +++ EEED E + E+ + EE++ +E+ + + +E +
Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300
Query: 374 FEEAERSLKDM 384
EE E + D+
Sbjct: 301 EEEEEEAAPDV 311
Score = 32.3 bits (72), Expect = 1.1
Identities = 20/86 (23%), Positives = 41/86 (47%)
Query: 316 EEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFE 375
EE +++ + EEE+EE+ E + E+ + EE++ +E+ + + +E + E
Sbjct: 246 EESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305
Query: 376 EAERSLKDMEESIRNLEQEISFDFGP 401
EA + E++ Q+ GP
Sbjct: 306 EAAPDVIFQEDTSHTSAQKAPELRGP 331
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 54.7 bits (130), Expect = 2e-07
Identities = 69/268 (25%), Positives = 104/268 (38%), Gaps = 39/268 (14%)
Query: 141 KKILIEDWKK--AREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKP-EREAKEQHQKL 197
KK+L+E+ K + +E E + GKK RT K+ E P + EAK Q
Sbjct: 1235 KKMLLEEIKANLSSDEDGSSDDEPEEGKK---------RTGKQNEENPGDEEAKNQVNSE 1285
Query: 198 WEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL------------DTDGD 245
+ +K + + + D G T+ + H E+ D D
Sbjct: 1286 SDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSD 1345
Query: 246 GALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQP 305
S + S D Q T + A + + RS + ++
Sbjct: 1346 FQESGVSEEVSESEDEQRPRTRSAKK--AELEENQRSYK-----QKKKRRRIKVQEDSSS 1398
Query: 306 PVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQP-----KPASPAEEDKMPPYDEQT 360
S+ EEEEE+EEEEEEE EEEEEEED + P K ++DK+ +T
Sbjct: 1399 ENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKL---RTET 1455
Query: 361 QAFIDAAQEARNKFEEAERSLKDMEESI 388
Q + +E R + E ER + + E I
Sbjct: 1456 QNALKEEEERRKRIAEREREREKLREVI 1483
Score = 37.7 bits (86), Expect = 0.026
Identities = 42/233 (18%), Positives = 90/233 (38%), Gaps = 39/233 (16%)
Query: 139 RLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLW 198
RLK+I + + + ++ K I+ + E+ E + K+ ++ + +K
Sbjct: 1090 RLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKK-- 1147
Query: 199 EEQLAAAKAQQEQELAADAFKELDDDMDGTVS-----------VTE---LQTHPEL-DTD 243
L + +++ ++ + + +++DD ++ VTE L +H +
Sbjct: 1148 RNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSS 1207
Query: 244 GDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEE 303
GD ALS++ + D D ++ + L ++ A + D ++
Sbjct: 1208 GDEALSKSVPVTVDDDDDDNDP-----------ENRIAKKMLLEEIKANLSSDEDGSSDD 1256
Query: 304 QPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPY 356
+P T ++ EE +EE + E DS+ +EE K P Y
Sbjct: 1257 EPEEGKKRTGKQNEENPGDEEAKNQVNSESDSD-----------SEESKKPRY 1298
Score = 30.4 bits (67), Expect = 4.1
Identities = 24/105 (22%), Positives = 48/105 (45%), Gaps = 8/105 (7%)
Query: 298 TEPKEEQPPVPSS----PTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKM 353
T+PKE + + +E+ E+ + +E +EE E ED + + + EE++
Sbjct: 1320 TKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQR 1379
Query: 354 PPYDEQTQAFI----DAAQEARNKFEEAERSLKDMEESIRNLEQE 394
++ + I D++ E ++ EE E ++ EE E+E
Sbjct: 1380 SYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEE 1424
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 54.7 bits (130), Expect = 2e-07
Identities = 69/268 (25%), Positives = 104/268 (38%), Gaps = 39/268 (14%)
Query: 141 KKILIEDWKK--AREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKP-EREAKEQHQKL 197
KK+L+E+ K + +E E + GKK RT K+ E P + EAK Q
Sbjct: 1273 KKMLLEEIKANLSSDEDGSSDDEPEEGKK---------RTGKQNEENPGDEEAKNQVNSE 1323
Query: 198 WEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL------------DTDGD 245
+ +K + + + D G T+ + H E+ D D
Sbjct: 1324 SDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSD 1383
Query: 246 GALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQP 305
S + S D Q T + A + + RS + ++
Sbjct: 1384 FQESGVSEEVSESEDEQRPRTRSAKK--AELEENQRSYK-----QKKKRRRIKVQEDSSS 1436
Query: 306 PVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQP-----KPASPAEEDKMPPYDEQT 360
S+ EEEEE+EEEEEEE EEEEEEED + P K ++DK+ +T
Sbjct: 1437 ENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKL---RTET 1493
Query: 361 QAFIDAAQEARNKFEEAERSLKDMEESI 388
Q + +E R + E ER + + E I
Sbjct: 1494 QNALKEEEERRKRIAEREREREKLREVI 1521
Score = 37.7 bits (86), Expect = 0.026
Identities = 42/233 (18%), Positives = 90/233 (38%), Gaps = 39/233 (16%)
Query: 139 RLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLW 198
RLK+I + + + ++ K I+ + E+ E + K+ ++ + +K
Sbjct: 1128 RLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKK-- 1185
Query: 199 EEQLAAAKAQQEQELAADAFKELDDDMDGTVS-----------VTE---LQTHPEL-DTD 243
L + +++ ++ + + +++DD ++ VTE L +H +
Sbjct: 1186 RNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSS 1245
Query: 244 GDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEE 303
GD ALS++ + D D ++ + L ++ A + D ++
Sbjct: 1246 GDEALSKSVPVTVDDDDDDNDP-----------ENRIAKKMLLEEIKANLSSDEDGSSDD 1294
Query: 304 QPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPY 356
+P T ++ EE +EE + E DS+ +EE K P Y
Sbjct: 1295 EPEEGKKRTGKQNEENPGDEEAKNQVNSESDSD-----------SEESKKPRY 1336
Score = 30.4 bits (67), Expect = 4.1
Identities = 24/105 (22%), Positives = 48/105 (45%), Gaps = 8/105 (7%)
Query: 298 TEPKEEQPPVPSS----PTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKM 353
T+PKE + + +E+ E+ + +E +EE E ED + + + EE++
Sbjct: 1358 TKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQR 1417
Query: 354 PPYDEQTQAFI----DAAQEARNKFEEAERSLKDMEESIRNLEQE 394
++ + I D++ E ++ EE E ++ EE E+E
Sbjct: 1418 SYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEE 1462
>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
Length = 543
Score = 54.7 bits (130), Expect = 2e-07
Identities = 69/270 (25%), Positives = 113/270 (41%), Gaps = 35/270 (12%)
Query: 146 EDWKKAR-----EEKQKKLIELQAGKKSLEDQVEMLR--TVKEEAEKPEREAKE-QHQKL 197
E+W K+R E K ++A K + + +L+ T++ EA + EA E Q Q+L
Sbjct: 277 EEWFKSRFTVLTESAAKNTDAVRAAKDEVSESRRLLKAKTLEIEACRGMNEALEKQLQEL 336
Query: 198 WEEQLAAAKAQQ------EQELA------ADAFKELDDDMDGTVSVT-ELQTHPELDTDG 244
++Q A A Q E EL A KE D ++ +++ E+ + +L
Sbjct: 337 EDKQNADISAMQDTINKLENELRTTKSEMARYLKEYQDLLNVKMALDIEIAAYRKLLEGE 396
Query: 245 DGALSEAEAQALLSGDTQTDA-----------TSFYDRVWAAIRDKYRSEALPTDLPAPS 293
+ LS ++ SG +Q+ TS Y + Y S +
Sbjct: 397 ETRLSFTSVGSITSGYSQSSQVFGRSAYGGLQTSSYLMSTRSFPSYYTSHVQEEQIEVEE 456
Query: 294 APDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKM 353
+ + +E + PS E E EEEE+++EEAEEEE E+ E E+ + A EE
Sbjct: 457 TIEAAKAEEAKDEPPS---EGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAKEEEEGGE 513
Query: 354 PPYDEQTQAFIDAAQEARNKFEEAERSLKD 383
E+T+ + ++ EE KD
Sbjct: 514 GEEGEETKEAEEEEKKVEGAGEEQAAKKKD 543
Score = 29.6 bits (65), Expect = 7.1
Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 317 EEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAA---QEARNK 373
E+E + A E+ E +QGE+ + + Y+E+ + DA EAR
Sbjct: 140 EQEIRDLRLAAEDATNEKQALQGER-EGLEETLRNLQARYEEEVLSREDAEGRLMEARKG 198
Query: 374 FEEAERSLKDMEESIRNLEQEISF 397
+EA + ++E+ I +L EISF
Sbjct: 199 ADEAALARAELEKRIDSLMDEISF 222
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 54.7 bits (130), Expect = 2e-07
Identities = 47/152 (30%), Positives = 68/152 (44%), Gaps = 16/152 (10%)
Query: 234 LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEAL-------P 286
L T PE + D ++ E + G T + V K EAL
Sbjct: 1273 LYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEV------KETGEALLPQEENRR 1326
Query: 287 TDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPAS 346
+ AP +P+ T P E+ P EEEEEEEEEEEEE EEE EEE+ E+ +
Sbjct: 1327 EETCAPVSPN-TSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGA 1385
Query: 347 PAEEDKMPPY--DEQTQAFIDAAQEARNKFEE 376
++E + P +++ A +D +E + EE
Sbjct: 1386 KSQEKEEPEISTEKEDSARLDDHEEEEEEDEE 1417
Score = 53.9 bits (128), Expect = 3e-07
Identities = 29/57 (50%), Positives = 35/57 (61%), Gaps = 3/57 (5%)
Query: 301 KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQP---KPASPAEEDKMP 354
+EE+ EEEEEEEE+EEEE EEEEEEE+ +Q P KP S A + K P
Sbjct: 1070 EEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRP 1126
Score = 49.7 bits (117), Expect = 7e-06
Identities = 24/47 (51%), Positives = 29/47 (61%)
Query: 309 SSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPP 355
S + EEEEEEE+EEEE EEEEEEED E + E+ + PP
Sbjct: 1065 SKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPP 1111
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Query: 296 DLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPP 355
DL +P+EE+ EEEEEEE EEEE E++ D E+ +P E++
Sbjct: 1346 DLIKPEEEEEE-EEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSAR 1404
Query: 356 YDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 395
D+ + + + + N+ +A+ ES ++E+
Sbjct: 1405 LDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEEL 1444
Score = 37.7 bits (86), Expect = 0.026
Identities = 32/123 (26%), Positives = 53/123 (43%), Gaps = 13/123 (10%)
Query: 245 DGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQ 304
+ A+SE E +A + + S ++ K E L T + +P + K +
Sbjct: 994 NAAVSEEEREAEKEAERLMEQASCWE--------KEEQEILSTRANSRQSPAKVQSKNKY 1045
Query: 305 PPVPSS-PTEEEE----EEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQ 359
P S P E E +E EE EEEE+EE+ E + E+ + EE++ +E
Sbjct: 1046 LHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEN 1105
Query: 360 TQA 362
Q+
Sbjct: 1106 IQS 1108
Score = 36.2 bits (82), Expect = 0.075
Identities = 47/252 (18%), Positives = 102/252 (40%), Gaps = 24/252 (9%)
Query: 165 GKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDD 224
G+K +D ++ +EE E+ E E +E+ ++ EE+ +++ + A KE +
Sbjct: 1340 GEKPEDDLIKP----EEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEI 1395
Query: 225 MDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSF--YDRVWAAIRDKYRS 282
L H E + + + + A D+ ++ + + ++ +
Sbjct: 1396 STEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLEN 1455
Query: 283 EALPTDL---PAPSAP--------DLTEPKEEQPPVPSSPTE--EEEEEEEEEEEEAEEE 329
+ DL P S P DLT +P + E E +EE E+A+++
Sbjct: 1456 QETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQ 1515
Query: 330 EEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIR 389
+++ EV E K +PA + D +T + + + ++ ++ + + +E+ R
Sbjct: 1516 DQKNSKEVDTEF-KEGNPATME----IDSETVQAVQSLTQESSEQDDTFQDCAETQEACR 1570
Query: 390 NLEQEISFDFGP 401
+L+ D P
Sbjct: 1571 SLQNYTRADQSP 1582
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.129 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,935,224
Number of Sequences: 37866
Number of extensions: 1463666
Number of successful extensions: 62394
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1386
Number of HSP's successfully gapped in prelim test: 1134
Number of HSP's that attempted gapping in prelim test: 15616
Number of HSP's gapped (non-prelim): 18489
length of query: 525
length of database: 18,247,518
effective HSP length: 107
effective length of query: 418
effective length of database: 14,195,856
effective search space: 5933867808
effective search space used: 5933867808
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.