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Search of human proteins with 47717112
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47717112 zinc finger, FYVE domain containing 9 isoform 1
[Homo sapiens]
(1366 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Hom... 2782 0.0
gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Hom... 2711 0.0
gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo... 1556 0.0
gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens] 583 e-166
gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens] 583 e-166
gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens] 85 5e-16
gi|189217917 FYVE, RhoGEF and PH domain containing 2 [Homo sapiens] 75 3e-13
gi|198041928 FYVE, RhoGEF and PH domain containing 4 [Homo sapiens] 74 7e-13
gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens] 71 6e-12
gi|13375827 phafin 2 [Homo sapiens] 70 1e-11
gi|24797153 faciogenital dysplasia protein [Homo sapiens] 69 2e-11
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 69 3e-11
gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens] 67 9e-11
gi|217272865 myotubularin related protein 4 [Homo sapiens] 67 9e-11
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 67 1e-10
gi|194018497 FYVE, RhoGEF and PH domain containing 5 [Homo sapiens] 66 3e-10
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 65 3e-10
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 65 3e-10
gi|153791377 apoptosis-inducing protein D [Homo sapiens] 65 3e-10
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 65 6e-10
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 65 6e-10
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 65 6e-10
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 65 6e-10
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens] 59 2e-08
gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens] 59 4e-08
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 59 4e-08
gi|4758528 hepatocyte growth factor-regulated tyrosine kinase su... 58 7e-08
gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Ho... 57 9e-08
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 57 9e-08
gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform... 57 1e-07
>gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Homo
sapiens]
Length = 1366
Score = 2782 bits (7212), Expect = 0.0
Identities = 1366/1366 (100%), Positives = 1366/1366 (100%)
Query: 1 MENYFQAEAYNLDKVLDEFEQNEDETVSSTLLDTKWNKILDPPSHRLSFNPTLASVNESA 60
MENYFQAEAYNLDKVLDEFEQNEDETVSSTLLDTKWNKILDPPSHRLSFNPTLASVNESA
Sbjct: 1 MENYFQAEAYNLDKVLDEFEQNEDETVSSTLLDTKWNKILDPPSHRLSFNPTLASVNESA 60
Query: 61 VSNESQPQLKVFSLAHSAPLTTEEEDHCANGQDCNLNPEIATMWIDENAVAEDQLIKRNY 120
VSNESQPQLKVFSLAHSAPLTTEEEDHCANGQDCNLNPEIATMWIDENAVAEDQLIKRNY
Sbjct: 61 VSNESQPQLKVFSLAHSAPLTTEEEDHCANGQDCNLNPEIATMWIDENAVAEDQLIKRNY 120
Query: 121 SWDDQCSAVEVGEKKCGNLACLPDEKNVLVVAVMHNCDKRTLQNDLQDCNNYNSQSLMDA 180
SWDDQCSAVEVGEKKCGNLACLPDEKNVLVVAVMHNCDKRTLQNDLQDCNNYNSQSLMDA
Sbjct: 121 SWDDQCSAVEVGEKKCGNLACLPDEKNVLVVAVMHNCDKRTLQNDLQDCNNYNSQSLMDA 180
Query: 181 FSCSLDNENRQTDQFSFSINESTEKDMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASV 240
FSCSLDNENRQTDQFSFSINESTEKDMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASV
Sbjct: 181 FSCSLDNENRQTDQFSFSINESTEKDMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASV 240
Query: 241 CSPSQLKDDGSIGRDPSMSAITSLTVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSP 300
CSPSQLKDDGSIGRDPSMSAITSLTVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSP
Sbjct: 241 CSPSQLKDDGSIGRDPSMSAITSLTVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSP 300
Query: 301 RTDLGSPNSFSHMSEGILMKKEPAEESTTEESLRSGLPLLLKPDMPNGSGRNNDCERCSD 360
RTDLGSPNSFSHMSEGILMKKEPAEESTTEESLRSGLPLLLKPDMPNGSGRNNDCERCSD
Sbjct: 301 RTDLGSPNSFSHMSEGILMKKEPAEESTTEESLRSGLPLLLKPDMPNGSGRNNDCERCSD 360
Query: 361 CLVPNEVRADENEGYEHEETLGTTEFLNMTEHFSESQDMTNWKLTKLNEMNDSQVNEEKE 420
CLVPNEVRADENEGYEHEETLGTTEFLNMTEHFSESQDMTNWKLTKLNEMNDSQVNEEKE
Sbjct: 361 CLVPNEVRADENEGYEHEETLGTTEFLNMTEHFSESQDMTNWKLTKLNEMNDSQVNEEKE 420
Query: 421 KFLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDS 480
KFLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDS
Sbjct: 421 KFLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDS 480
Query: 481 YGMQDPGVSFVPKTLPSKEDSVTEEKEIEESKSECYSNIYEQRGNEATEGSGLLLNSTGD 540
YGMQDPGVSFVPKTLPSKEDSVTEEKEIEESKSECYSNIYEQRGNEATEGSGLLLNSTGD
Sbjct: 481 YGMQDPGVSFVPKTLPSKEDSVTEEKEIEESKSECYSNIYEQRGNEATEGSGLLLNSTGD 540
Query: 541 LMKKNYLHNFCSQVPSVLGQSSPKVVASLPSISVPFGGARPKQPSNLKLQIPKPLSDHLQ 600
LMKKNYLHNFCSQVPSVLGQSSPKVVASLPSISVPFGGARPKQPSNLKLQIPKPLSDHLQ
Sbjct: 541 LMKKNYLHNFCSQVPSVLGQSSPKVVASLPSISVPFGGARPKQPSNLKLQIPKPLSDHLQ 600
Query: 601 NDFPANSGNNTKNKNDILGKAKLGENSATNVCSPSLGNISNVDTNGEHLESYEAEISTRP 660
NDFPANSGNNTKNKNDILGKAKLGENSATNVCSPSLGNISNVDTNGEHLESYEAEISTRP
Sbjct: 601 NDFPANSGNNTKNKNDILGKAKLGENSATNVCSPSLGNISNVDTNGEHLESYEAEISTRP 660
Query: 661 CLALAPDSPDNDLRAGQFGISARKPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHH 720
CLALAPDSPDNDLRAGQFGISARKPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHH
Sbjct: 661 CLALAPDSPDNDLRAGQFGISARKPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHH 720
Query: 721 CRACGKVFCASCCSLKCKLLYMDRKEARVCVICHSVLMNVAQPREQRRVWFADGILPNGE 780
CRACGKVFCASCCSLKCKLLYMDRKEARVCVICHSVLMNVAQPREQRRVWFADGILPNGE
Sbjct: 721 CRACGKVFCASCCSLKCKLLYMDRKEARVCVICHSVLMNVAQPREQRRVWFADGILPNGE 780
Query: 781 VADAAKLTMNGTSSAGTLAVSHDPVKPVTTSPLPAETDICLFSGSITQVGSPVGSAMNLI 840
VADAAKLTMNGTSSAGTLAVSHDPVKPVTTSPLPAETDICLFSGSITQVGSPVGSAMNLI
Sbjct: 781 VADAAKLTMNGTSSAGTLAVSHDPVKPVTTSPLPAETDICLFSGSITQVGSPVGSAMNLI 840
Query: 841 PEDGLPPILISTGVKGDYAVEEKPSQISVMQQLEDGGPDPLVFVLNANLLSMVKIVNYVN 900
PEDGLPPILISTGVKGDYAVEEKPSQISVMQQLEDGGPDPLVFVLNANLLSMVKIVNYVN
Sbjct: 841 PEDGLPPILISTGVKGDYAVEEKPSQISVMQQLEDGGPDPLVFVLNANLLSMVKIVNYVN 900
Query: 901 RKCWCFTTKGMHAVGQSEIVILLQCLPDEKCLPKDIFNHFVQLYRDALAGNVVSNLGHSF 960
RKCWCFTTKGMHAVGQSEIVILLQCLPDEKCLPKDIFNHFVQLYRDALAGNVVSNLGHSF
Sbjct: 901 RKCWCFTTKGMHAVGQSEIVILLQCLPDEKCLPKDIFNHFVQLYRDALAGNVVSNLGHSF 960
Query: 961 FSQSFLGSKEHGGFLYVTSTYQSLQDLVLPTPPYLFGILIQKWETPWAKVFPIRLMLRLG 1020
FSQSFLGSKEHGGFLYVTSTYQSLQDLVLPTPPYLFGILIQKWETPWAKVFPIRLMLRLG
Sbjct: 961 FSQSFLGSKEHGGFLYVTSTYQSLQDLVLPTPPYLFGILIQKWETPWAKVFPIRLMLRLG 1020
Query: 1021 AEYRLYPCPLFSVRFRKPLFGETGHTIMNLLADFRNYQYTLPVVQGLVVDMEVRKTSIKI 1080
AEYRLYPCPLFSVRFRKPLFGETGHTIMNLLADFRNYQYTLPVVQGLVVDMEVRKTSIKI
Sbjct: 1021 AEYRLYPCPLFSVRFRKPLFGETGHTIMNLLADFRNYQYTLPVVQGLVVDMEVRKTSIKI 1080
Query: 1081 PSNRYNEMMKAMNKSNEHVLAGGACFNEKADSHLVCVQNDDGNYQTQAISIHNQPRKVTG 1140
PSNRYNEMMKAMNKSNEHVLAGGACFNEKADSHLVCVQNDDGNYQTQAISIHNQPRKVTG
Sbjct: 1081 PSNRYNEMMKAMNKSNEHVLAGGACFNEKADSHLVCVQNDDGNYQTQAISIHNQPRKVTG 1140
Query: 1141 ASFFVFSGALKSSSGYLAKSSIVEDGVMVQITAENMDSLRQALREMKDFTITCGKADAEE 1200
ASFFVFSGALKSSSGYLAKSSIVEDGVMVQITAENMDSLRQALREMKDFTITCGKADAEE
Sbjct: 1141 ASFFVFSGALKSSSGYLAKSSIVEDGVMVQITAENMDSLRQALREMKDFTITCGKADAEE 1200
Query: 1201 PQEHIHIQWVDDDKNVSKGVVSPIDGKSMETITNVKIFHGSEYKANGKVIRWTEVFFLEN 1260
PQEHIHIQWVDDDKNVSKGVVSPIDGKSMETITNVKIFHGSEYKANGKVIRWTEVFFLEN
Sbjct: 1201 PQEHIHIQWVDDDKNVSKGVVSPIDGKSMETITNVKIFHGSEYKANGKVIRWTEVFFLEN 1260
Query: 1261 DDQHNCLSDPADHSRLTEHVAKAFCLALCPHLKLLKEDGMTKLGLRVTLDSDQVGYQAGS 1320
DDQHNCLSDPADHSRLTEHVAKAFCLALCPHLKLLKEDGMTKLGLRVTLDSDQVGYQAGS
Sbjct: 1261 DDQHNCLSDPADHSRLTEHVAKAFCLALCPHLKLLKEDGMTKLGLRVTLDSDQVGYQAGS 1320
Query: 1321 NGQPLPSQYMNDLDSALVPVIHGGACQLSEGPVVMELIFYILENIV 1366
NGQPLPSQYMNDLDSALVPVIHGGACQLSEGPVVMELIFYILENIV
Sbjct: 1321 NGQPLPSQYMNDLDSALVPVIHGGACQLSEGPVVMELIFYILENIV 1366
>gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Homo
sapiens]
Length = 1425
Score = 2711 bits (7028), Expect = 0.0
Identities = 1352/1425 (94%), Positives = 1355/1425 (95%), Gaps = 59/1425 (4%)
Query: 1 MENYFQAEAYNLDKVLDEFEQNEDETVSSTLLDTKWNKILDPPSHRLSFNPTLASVNESA 60
MENYFQAEAYNLDKVLDEFEQNEDETVSSTLLDTKWNKILDPPSHRLSFNPTLASVNESA
Sbjct: 1 MENYFQAEAYNLDKVLDEFEQNEDETVSSTLLDTKWNKILDPPSHRLSFNPTLASVNESA 60
Query: 61 VSNESQPQLKVFSLAHSAPLTTEEEDHCANGQDCNLNPEIATMWIDENAVAEDQLIKRNY 120
VSNESQPQLKVFSLAHSAPLTTEEEDHCANGQDCNLNPEIATMWIDENAVAEDQLIKRNY
Sbjct: 61 VSNESQPQLKVFSLAHSAPLTTEEEDHCANGQDCNLNPEIATMWIDENAVAEDQLIKRNY 120
Query: 121 SWDDQCSAVEVGEKKCGNLACLPDEKNVLVVAVMHNCDKRTLQNDLQDCNNYNSQSLMDA 180
SWDDQCSAVEVGEKKCGNLACLPDEKNVLVVAVMHNCDKRTLQNDLQDCNNYNSQSLMDA
Sbjct: 121 SWDDQCSAVEVGEKKCGNLACLPDEKNVLVVAVMHNCDKRTLQNDLQDCNNYNSQSLMDA 180
Query: 181 FSCSLDNENRQTDQFSFSINESTEKDMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASV 240
FSCSLDNENRQTDQFSFSINESTEKDMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASV
Sbjct: 181 FSCSLDNENRQTDQFSFSINESTEKDMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASV 240
Query: 241 CSPSQLKDDGSIGRDPSMSAITSLTVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSP 300
CSPSQLKDDGSIGRDPSMSAITSLTVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSP
Sbjct: 241 CSPSQLKDDGSIGRDPSMSAITSLTVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSP 300
Query: 301 RTDLGSPNSFSHMSEGILMKKEPAEESTTEESLRSGLPLLLKPDMPNGSGRNNDCERCSD 360
RTDLGSPNSFSHMSEGILMKKEPAEESTTEESLRSGLPLLLKPDMPNGSGRNNDCERCSD
Sbjct: 301 RTDLGSPNSFSHMSEGILMKKEPAEESTTEESLRSGLPLLLKPDMPNGSGRNNDCERCSD 360
Query: 361 CLVPNEVRADENEGYEHEETLGTTEFLNMTEHFSESQDMTNWKLTKLNEMNDSQVNEEKE 420
CLVPNEVRADENEGYEHEETLGTTEFLNMTEHFSESQDMTNWKLTKLNEMNDSQVNEEKE
Sbjct: 361 CLVPNEVRADENEGYEHEETLGTTEFLNMTEHFSESQDMTNWKLTKLNEMNDSQVNEEKE 420
Query: 421 KFLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDS 480
KFLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDS
Sbjct: 421 KFLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDS 480
Query: 481 YGMQDPGVSFVPKTLPSKEDSVTEEKEIEESKSECYSNIYEQRGNEATEGSGLLLNSTGD 540
YGMQDPGVSFVPKTLPSKEDSVTEEKEIEESKSECYSNIYEQRGNEATEGSGLLLNSTGD
Sbjct: 481 YGMQDPGVSFVPKTLPSKEDSVTEEKEIEESKSECYSNIYEQRGNEATEGSGLLLNSTGD 540
Query: 541 LMKKNYLHNFCSQVPSVLGQSSPKVVASLPSISVPFGGARPKQPSNLKLQIPKPLSDHLQ 600
LMKKNYLHNFCSQVPSVLGQSSPKVVASLPSISVPFGGARPKQPSNLKLQIPKPLSDHLQ
Sbjct: 541 LMKKNYLHNFCSQVPSVLGQSSPKVVASLPSISVPFGGARPKQPSNLKLQIPKPLSDHLQ 600
Query: 601 NDFPANSGNNTKNKNDILGKAKLGENSATNVCSPSLGNISNVDTNGEHLESYEAEISTRP 660
NDFPANSGNNTKNKNDILGKAKLGENSATNVCSPSLGNISNVDTNGEHLESYEAEISTRP
Sbjct: 601 NDFPANSGNNTKNKNDILGKAKLGENSATNVCSPSLGNISNVDTNGEHLESYEAEISTRP 660
Query: 661 CLALAPDSPDNDLRAGQFGISARKPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHH 720
CLALAPDSPDNDLRAGQFGISARKPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHH
Sbjct: 661 CLALAPDSPDNDLRAGQFGISARKPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHH 720
Query: 721 CRACGKVFCASCCSLKCKLLYMDRKEARVCVICHSVLMN--------------------- 759
CRACGKVFCASCCSLKCKLLYMDRKEARVCVICHSVLMN
Sbjct: 721 CRACGKVFCASCCSLKCKLLYMDRKEARVCVICHSVLMNAQAWENMMSASSQSPNPNNPA 780
Query: 760 ----VAQPREQRR-----------VWFADGIL--PNGEVA-------------------- 782
P +Q + V G+L P EVA
Sbjct: 781 EYCSTIPPLQQAQASGALSSPPPTVMVPVGVLKHPGAEVAQPREQRRVWFADGILPNGEV 840
Query: 783 -DAAKLTMNGTSSAGTLAVSHDPVKPVTTSPLPAETDICLFSGSITQVGSPVGSAMNLIP 841
DAAKLTMNGTSSAGTLAVSHDPVKPVTTSPLPAETDICLFSGSITQVGSPVGSAMNLIP
Sbjct: 841 ADAAKLTMNGTSSAGTLAVSHDPVKPVTTSPLPAETDICLFSGSITQVGSPVGSAMNLIP 900
Query: 842 EDGLPPILISTGVKGDYAVEEKPSQISVMQQLEDGGPDPLVFVLNANLLSMVKIVNYVNR 901
EDGLPPILISTGVKGDYAVEEKPSQISVMQQLEDGGPDPLVFVLNANLLSMVKIVNYVNR
Sbjct: 901 EDGLPPILISTGVKGDYAVEEKPSQISVMQQLEDGGPDPLVFVLNANLLSMVKIVNYVNR 960
Query: 902 KCWCFTTKGMHAVGQSEIVILLQCLPDEKCLPKDIFNHFVQLYRDALAGNVVSNLGHSFF 961
KCWCFTTKGMHAVGQSEIVILLQCLPDEKCLPKDIFNHFVQLYRDALAGNVVSNLGHSFF
Sbjct: 961 KCWCFTTKGMHAVGQSEIVILLQCLPDEKCLPKDIFNHFVQLYRDALAGNVVSNLGHSFF 1020
Query: 962 SQSFLGSKEHGGFLYVTSTYQSLQDLVLPTPPYLFGILIQKWETPWAKVFPIRLMLRLGA 1021
SQSFLGSKEHGGFLYVTSTYQSLQDLVLPTPPYLFGILIQKWETPWAKVFPIRLMLRLGA
Sbjct: 1021 SQSFLGSKEHGGFLYVTSTYQSLQDLVLPTPPYLFGILIQKWETPWAKVFPIRLMLRLGA 1080
Query: 1022 EYRLYPCPLFSVRFRKPLFGETGHTIMNLLADFRNYQYTLPVVQGLVVDMEVRKTSIKIP 1081
EYRLYPCPLFSVRFRKPLFGETGHTIMNLLADFRNYQYTLPVVQGLVVDMEVRKTSIKIP
Sbjct: 1081 EYRLYPCPLFSVRFRKPLFGETGHTIMNLLADFRNYQYTLPVVQGLVVDMEVRKTSIKIP 1140
Query: 1082 SNRYNEMMKAMNKSNEHVLAGGACFNEKADSHLVCVQNDDGNYQTQAISIHNQPRKVTGA 1141
SNRYNEMMKAMNKSNEHVLAGGACFNEKADSHLVCVQNDDGNYQTQAISIHNQPRKVTGA
Sbjct: 1141 SNRYNEMMKAMNKSNEHVLAGGACFNEKADSHLVCVQNDDGNYQTQAISIHNQPRKVTGA 1200
Query: 1142 SFFVFSGALKSSSGYLAKSSIVEDGVMVQITAENMDSLRQALREMKDFTITCGKADAEEP 1201
SFFVFSGALKSSSGYLAKSSIVEDGVMVQITAENMDSLRQALREMKDFTITCGKADAEEP
Sbjct: 1201 SFFVFSGALKSSSGYLAKSSIVEDGVMVQITAENMDSLRQALREMKDFTITCGKADAEEP 1260
Query: 1202 QEHIHIQWVDDDKNVSKGVVSPIDGKSMETITNVKIFHGSEYKANGKVIRWTEVFFLEND 1261
QEHIHIQWVDDDKNVSKGVVSPIDGKSMETITNVKIFHGSEYKANGKVIRWTEVFFLEND
Sbjct: 1261 QEHIHIQWVDDDKNVSKGVVSPIDGKSMETITNVKIFHGSEYKANGKVIRWTEVFFLEND 1320
Query: 1262 DQHNCLSDPADHSRLTEHVAKAFCLALCPHLKLLKEDGMTKLGLRVTLDSDQVGYQAGSN 1321
DQHNCLSDPADHSRLTEHVAKAFCLALCPHLKLLKEDGMTKLGLRVTLDSDQVGYQAGSN
Sbjct: 1321 DQHNCLSDPADHSRLTEHVAKAFCLALCPHLKLLKEDGMTKLGLRVTLDSDQVGYQAGSN 1380
Query: 1322 GQPLPSQYMNDLDSALVPVIHGGACQLSEGPVVMELIFYILENIV 1366
GQPLPSQYMNDLDSALVPVIHGGACQLSEGPVVMELIFYILENIV
Sbjct: 1381 GQPLPSQYMNDLDSALVPVIHGGACQLSEGPVVMELIFYILENIV 1425
>gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo
sapiens]
Length = 762
Score = 1556 bits (4030), Expect = 0.0
Identities = 759/759 (100%), Positives = 759/759 (100%)
Query: 1 MENYFQAEAYNLDKVLDEFEQNEDETVSSTLLDTKWNKILDPPSHRLSFNPTLASVNESA 60
MENYFQAEAYNLDKVLDEFEQNEDETVSSTLLDTKWNKILDPPSHRLSFNPTLASVNESA
Sbjct: 1 MENYFQAEAYNLDKVLDEFEQNEDETVSSTLLDTKWNKILDPPSHRLSFNPTLASVNESA 60
Query: 61 VSNESQPQLKVFSLAHSAPLTTEEEDHCANGQDCNLNPEIATMWIDENAVAEDQLIKRNY 120
VSNESQPQLKVFSLAHSAPLTTEEEDHCANGQDCNLNPEIATMWIDENAVAEDQLIKRNY
Sbjct: 61 VSNESQPQLKVFSLAHSAPLTTEEEDHCANGQDCNLNPEIATMWIDENAVAEDQLIKRNY 120
Query: 121 SWDDQCSAVEVGEKKCGNLACLPDEKNVLVVAVMHNCDKRTLQNDLQDCNNYNSQSLMDA 180
SWDDQCSAVEVGEKKCGNLACLPDEKNVLVVAVMHNCDKRTLQNDLQDCNNYNSQSLMDA
Sbjct: 121 SWDDQCSAVEVGEKKCGNLACLPDEKNVLVVAVMHNCDKRTLQNDLQDCNNYNSQSLMDA 180
Query: 181 FSCSLDNENRQTDQFSFSINESTEKDMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASV 240
FSCSLDNENRQTDQFSFSINESTEKDMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASV
Sbjct: 181 FSCSLDNENRQTDQFSFSINESTEKDMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASV 240
Query: 241 CSPSQLKDDGSIGRDPSMSAITSLTVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSP 300
CSPSQLKDDGSIGRDPSMSAITSLTVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSP
Sbjct: 241 CSPSQLKDDGSIGRDPSMSAITSLTVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSP 300
Query: 301 RTDLGSPNSFSHMSEGILMKKEPAEESTTEESLRSGLPLLLKPDMPNGSGRNNDCERCSD 360
RTDLGSPNSFSHMSEGILMKKEPAEESTTEESLRSGLPLLLKPDMPNGSGRNNDCERCSD
Sbjct: 301 RTDLGSPNSFSHMSEGILMKKEPAEESTTEESLRSGLPLLLKPDMPNGSGRNNDCERCSD 360
Query: 361 CLVPNEVRADENEGYEHEETLGTTEFLNMTEHFSESQDMTNWKLTKLNEMNDSQVNEEKE 420
CLVPNEVRADENEGYEHEETLGTTEFLNMTEHFSESQDMTNWKLTKLNEMNDSQVNEEKE
Sbjct: 361 CLVPNEVRADENEGYEHEETLGTTEFLNMTEHFSESQDMTNWKLTKLNEMNDSQVNEEKE 420
Query: 421 KFLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDS 480
KFLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDS
Sbjct: 421 KFLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDS 480
Query: 481 YGMQDPGVSFVPKTLPSKEDSVTEEKEIEESKSECYSNIYEQRGNEATEGSGLLLNSTGD 540
YGMQDPGVSFVPKTLPSKEDSVTEEKEIEESKSECYSNIYEQRGNEATEGSGLLLNSTGD
Sbjct: 481 YGMQDPGVSFVPKTLPSKEDSVTEEKEIEESKSECYSNIYEQRGNEATEGSGLLLNSTGD 540
Query: 541 LMKKNYLHNFCSQVPSVLGQSSPKVVASLPSISVPFGGARPKQPSNLKLQIPKPLSDHLQ 600
LMKKNYLHNFCSQVPSVLGQSSPKVVASLPSISVPFGGARPKQPSNLKLQIPKPLSDHLQ
Sbjct: 541 LMKKNYLHNFCSQVPSVLGQSSPKVVASLPSISVPFGGARPKQPSNLKLQIPKPLSDHLQ 600
Query: 601 NDFPANSGNNTKNKNDILGKAKLGENSATNVCSPSLGNISNVDTNGEHLESYEAEISTRP 660
NDFPANSGNNTKNKNDILGKAKLGENSATNVCSPSLGNISNVDTNGEHLESYEAEISTRP
Sbjct: 601 NDFPANSGNNTKNKNDILGKAKLGENSATNVCSPSLGNISNVDTNGEHLESYEAEISTRP 660
Query: 661 CLALAPDSPDNDLRAGQFGISARKPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHH 720
CLALAPDSPDNDLRAGQFGISARKPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHH
Sbjct: 661 CLALAPDSPDNDLRAGQFGISARKPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHH 720
Query: 721 CRACGKVFCASCCSLKCKLLYMDRKEARVCVICHSVLMN 759
CRACGKVFCASCCSLKCKLLYMDRKEARVCVICHSVLMN
Sbjct: 721 CRACGKVFCASCCSLKCKLLYMDRKEARVCVICHSVLMN 759
>gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 583 bits (1504), Expect = e-166
Identities = 311/608 (51%), Positives = 419/608 (68%), Gaps = 28/608 (4%)
Query: 777 PNGEVADAAKLTMNG------TSSAGTL-----AVSHDPVKPV-----TTSPLPAETDIC 820
P +V KL+MN TS + TL A + +P P + P+ + +D
Sbjct: 940 PISQVPSVEKLSMNTGNEGLPTSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYR 999
Query: 821 LFSGSITQVGSPVGSAMNLIP--EDGLPPILISTGVKGDY-AVEEKPSQISVMQQLEDGG 877
L + + V + ++L+P ED LPP+L+++G KG VEE PS ++ LE G
Sbjct: 1000 L----LCDINKYVCNKISLLPNDEDSLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEG 1055
Query: 878 PDPLVFVLNANLLSMVKIVNYVNRKCWCFTTKGMHAVGQSEIVILLQCLPDEKCLPKDIF 937
P+ FVLNANLL VK + Y + K W F+T G+H +GQ+EI+ILL CLP+E +PKDIF
Sbjct: 1056 FHPVTFVLNANLLVNVKFIFYSSDKYWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIF 1115
Query: 938 NHFVQLYRDALAGNVVSNLGHSFFSQSFLGSKEHGGFLYVTSTYQSLQDLVLPTPPYLFG 997
F+ +Y+DAL G + NL + F++SFL SK+HGGFL++T T+Q L DL LP+ P+L G
Sbjct: 1116 RLFITIYKDALKGKYIENLDNITFTESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCG 1175
Query: 998 ILIQKWETPWAKVFPIRLMLRLGAEYRLYPCPLFSVRFRKPLFGETGHTIMNLLADFRNY 1057
ILIQK E PWAKVFP+RLMLRLGAEY+ YP PL S+R RKPLFGE GHTIMNLL D RNY
Sbjct: 1176 ILIQKLEIPWAKVFPMRLMLRLGAEYKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNY 1235
Query: 1058 QYTLPVVQGLVVDMEVRKTSIKIPSNRYNEMMKAMNKSNEHVLAGGACFNEKADSHLVCV 1117
QYTL + L++ ME+ K+ IKIP +Y+++MK +N SNEHV++ GA F+ +ADSHLVC+
Sbjct: 1236 QYTLHNIDQLLIHMEMGKSCIKIPRKKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCI 1295
Query: 1118 QNDDGNYQTQAISIHNQPRKVTGASFFVFSGALKSSSGYLAKSSIVEDGVMVQITAENMD 1177
QN DG Y+TQA S PRKVTGASF VF+GALK+SSG+LAKSSIVEDG+MVQIT E M+
Sbjct: 1296 QN-DGIYETQANSATGHPRKVTGASFVVFNGALKTSSGFLAKSSIVEDGLMVQITPETMN 1354
Query: 1178 SLRQALREMKDFTITCGKADAEEPQEHIHIQWVDDDKNVSKGVVSPIDGKSMETITNVKI 1237
LR ALRE KDF ITCGK DA + +E++ I WVD ++ +KGV+S +DG S++ + KI
Sbjct: 1355 GLRLALREQKDFKITCGKVDAVDLREYVDICWVDAEEKGNKGVISSVDGISLQGFPSEKI 1414
Query: 1238 FHGSEYKANGKVIRWTEVFFLENDDQHNCLSDPADHSRLTEHVAKAFCLALCPHLKLLKE 1297
++++ + K+++ TEVF+ D + LS + + +A A ALCPHLK LK
Sbjct: 1415 KLEADFETDEKIVKCTEVFYFLKDQDLSILS---TSYQFAKEIAMACSAALCPHLKTLKS 1471
Query: 1298 DGMTKLGLRVTLDSDQVGYQAGSNGQPLPSQYMNDLDSALVPVIHGGACQLSEGPVVMEL 1357
+GM K+GLRV++D+D V +QAGS GQ LP Y+NDLDSAL+PVIHGG S P+ +EL
Sbjct: 1472 NGMNKIGLRVSIDTDMVEFQAGSEGQLLPQHYLNDLDSALIPVIHGGTSN-SSLPLEIEL 1530
Query: 1358 IFYILENI 1365
+F+I+E++
Sbjct: 1531 VFFIIEHL 1538
Score = 155 bits (392), Expect = 2e-37
Identities = 227/958 (23%), Positives = 373/958 (38%), Gaps = 205/958 (21%)
Query: 1 MENYFQAEAYNLDKVLDEFEQNEDE----------------TVSSTLLDTKWNKILDPP- 43
M++YF+A +LDK+LD+FEQN DE +VSS L ++ +L
Sbjct: 1 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 60
Query: 44 -------SHRLSFNPTLASVNESAV----SNESQPQLKVFSLAHSAPLTTEEE------D 86
S S+ +S+NE + S +++ + L S T +E
Sbjct: 61 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 120
Query: 87 HCANGQDCNLNPEIATMWIDENAVAEDQLIKRNYSWDDQCSAVEVGEKKCGNLACLPDEK 146
C+ C+L ++ + +A ++ IK+ D + +A + +++ P
Sbjct: 121 RCSK-PICDLISDMGNL---VHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTP--- 173
Query: 147 NVLVVAVMHNCDK-RTLQNDLQDCNNYNSQSLMDAFSCSLDNENRQTDQFSFSINESTEK 205
V + H+ D R QND+ + +D + +S + N +K
Sbjct: 174 --CVSSTDHDSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKK 231
Query: 206 DMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASVCSP-SQLKDDGSIGRDPSMSAITSL 264
N + + N R + + + D L P LKD G + + ++ IT+
Sbjct: 232 IFNQLESIVDFNMSSALTRQSSKMFH-AKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAA 290
Query: 265 TVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSPRTDLGSPNSFSHMSEGILMKKEPA 324
+ +G +N EDL S+ R + FS + ++K+
Sbjct: 291 ---ECLKEEGKTSALTCSLPKN----EDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQ 343
Query: 325 EESTTEE--------SLRSGLPLLLKPDMPNGSGRNNDCERCSDCLVPNEVRADENEGYE 376
E+S + + S L + K D+P+ L+ ++ R D +E
Sbjct: 344 EDSKSLDLKDNDVIQDSSSALHVSSK-DVPSSLSCLPASGSMCGSLIESKARGDFLPQHE 402
Query: 377 HEETLGTT-----EFLNMT----EHFSESQDMTNWKLTKL------NEMNDSQVNEEKEK 421
H++ + E N E F E+ + K + M D +++ ++
Sbjct: 403 HKDNIQDAVTIHEEIQNSVVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQT- 461
Query: 422 FLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDSY 481
+ + E +G V + GL GT + ES +C I+T ++N + Y
Sbjct: 462 ---VIRAESLDGGDTSSTVVESQEGLS--GTHVPESSDC-CEGFINTFSSNDMDGQDLDY 515
Query: 482 GMQDPGVSFVPKTLPSKEDS-VTE-----------EKEIEESKSECYSNIYEQRGNEATE 529
D G P ++ D+ +TE E+ + +SKS+ N + +G +
Sbjct: 516 FNIDEGAKSGPLISDAELDAFLTEQYLQTTNIKSFEENVNDSKSQM--NQIDMKGLDDGN 573
Query: 530 GSGLLLNS-TGDLMKKNYLHNFCSQVPSV--------LGQSSP-KVVASLPSI------- 572
+ + N+ G + + + ++ C V LG+ S V LP+
Sbjct: 574 INNIYFNAEAGAIGESHGINIICETVDKQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQ 633
Query: 573 -------SVPFGGARPKQPSNLKLQIPKPLSDHLQNDFPANSGNNTKNKNDILGKAKLGE 625
S GGARPKQ +L + + D + D P + + ++ +
Sbjct: 634 LSVSDINSQSVGGARPKQLFSLPSRT-RSSKDLNKPDVPDTIESEPSTADTVVPITCAID 692
Query: 626 NSATNVCSPSLGNISNVDTNGEHLESYEAEISTRPCLALAPDSPDNDLRAGQFGISARKP 685
++A S + N ++++N E S+ A P+N + G
Sbjct: 693 STADPQVSFN-SNYIDIESNSEGGSSFVT--------ANEDSVPENTCKEG--------- 734
Query: 686 FTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRK 745
LG+ P WVPDS+APNCM C+ +FTFTKRRHHCRACGKVFC CC+ KCKL Y++ K
Sbjct: 735 -LVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLE-K 792
Query: 746 EARVCVIC------------------------HSVLMNVAQP------------------ 763
EARVCV+C HS QP
Sbjct: 793 EARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQTSSIPSPATLPVS 852
Query: 764 ------------REQRRVWFADGILPNGEVADAAKLTMNGTSSAGTLAVSHD--PVKP 807
+EQ+RVWFADGILPNGEVAD KL S+G+ S D P+ P
Sbjct: 853 ALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKL------SSGSKRCSEDFSPLSP 904
>gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 583 bits (1504), Expect = e-166
Identities = 311/608 (51%), Positives = 419/608 (68%), Gaps = 28/608 (4%)
Query: 777 PNGEVADAAKLTMNG------TSSAGTL-----AVSHDPVKPV-----TTSPLPAETDIC 820
P +V KL+MN TS + TL A + +P P + P+ + +D
Sbjct: 940 PISQVPSVEKLSMNTGNEGLPTSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYR 999
Query: 821 LFSGSITQVGSPVGSAMNLIP--EDGLPPILISTGVKGDY-AVEEKPSQISVMQQLEDGG 877
L + + V + ++L+P ED LPP+L+++G KG VEE PS ++ LE G
Sbjct: 1000 L----LCDINKYVCNKISLLPNDEDSLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEG 1055
Query: 878 PDPLVFVLNANLLSMVKIVNYVNRKCWCFTTKGMHAVGQSEIVILLQCLPDEKCLPKDIF 937
P+ FVLNANLL VK + Y + K W F+T G+H +GQ+EI+ILL CLP+E +PKDIF
Sbjct: 1056 FHPVTFVLNANLLVNVKFIFYSSDKYWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIF 1115
Query: 938 NHFVQLYRDALAGNVVSNLGHSFFSQSFLGSKEHGGFLYVTSTYQSLQDLVLPTPPYLFG 997
F+ +Y+DAL G + NL + F++SFL SK+HGGFL++T T+Q L DL LP+ P+L G
Sbjct: 1116 RLFITIYKDALKGKYIENLDNITFTESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCG 1175
Query: 998 ILIQKWETPWAKVFPIRLMLRLGAEYRLYPCPLFSVRFRKPLFGETGHTIMNLLADFRNY 1057
ILIQK E PWAKVFP+RLMLRLGAEY+ YP PL S+R RKPLFGE GHTIMNLL D RNY
Sbjct: 1176 ILIQKLEIPWAKVFPMRLMLRLGAEYKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNY 1235
Query: 1058 QYTLPVVQGLVVDMEVRKTSIKIPSNRYNEMMKAMNKSNEHVLAGGACFNEKADSHLVCV 1117
QYTL + L++ ME+ K+ IKIP +Y+++MK +N SNEHV++ GA F+ +ADSHLVC+
Sbjct: 1236 QYTLHNIDQLLIHMEMGKSCIKIPRKKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCI 1295
Query: 1118 QNDDGNYQTQAISIHNQPRKVTGASFFVFSGALKSSSGYLAKSSIVEDGVMVQITAENMD 1177
QN DG Y+TQA S PRKVTGASF VF+GALK+SSG+LAKSSIVEDG+MVQIT E M+
Sbjct: 1296 QN-DGIYETQANSATGHPRKVTGASFVVFNGALKTSSGFLAKSSIVEDGLMVQITPETMN 1354
Query: 1178 SLRQALREMKDFTITCGKADAEEPQEHIHIQWVDDDKNVSKGVVSPIDGKSMETITNVKI 1237
LR ALRE KDF ITCGK DA + +E++ I WVD ++ +KGV+S +DG S++ + KI
Sbjct: 1355 GLRLALREQKDFKITCGKVDAVDLREYVDICWVDAEEKGNKGVISSVDGISLQGFPSEKI 1414
Query: 1238 FHGSEYKANGKVIRWTEVFFLENDDQHNCLSDPADHSRLTEHVAKAFCLALCPHLKLLKE 1297
++++ + K+++ TEVF+ D + LS + + +A A ALCPHLK LK
Sbjct: 1415 KLEADFETDEKIVKCTEVFYFLKDQDLSILS---TSYQFAKEIAMACSAALCPHLKTLKS 1471
Query: 1298 DGMTKLGLRVTLDSDQVGYQAGSNGQPLPSQYMNDLDSALVPVIHGGACQLSEGPVVMEL 1357
+GM K+GLRV++D+D V +QAGS GQ LP Y+NDLDSAL+PVIHGG S P+ +EL
Sbjct: 1472 NGMNKIGLRVSIDTDMVEFQAGSEGQLLPQHYLNDLDSALIPVIHGGTSN-SSLPLEIEL 1530
Query: 1358 IFYILENI 1365
+F+I+E++
Sbjct: 1531 VFFIIEHL 1538
Score = 155 bits (392), Expect = 2e-37
Identities = 227/958 (23%), Positives = 373/958 (38%), Gaps = 205/958 (21%)
Query: 1 MENYFQAEAYNLDKVLDEFEQNEDE----------------TVSSTLLDTKWNKILDPP- 43
M++YF+A +LDK+LD+FEQN DE +VSS L ++ +L
Sbjct: 1 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 60
Query: 44 -------SHRLSFNPTLASVNESAV----SNESQPQLKVFSLAHSAPLTTEEE------D 86
S S+ +S+NE + S +++ + L S T +E
Sbjct: 61 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 120
Query: 87 HCANGQDCNLNPEIATMWIDENAVAEDQLIKRNYSWDDQCSAVEVGEKKCGNLACLPDEK 146
C+ C+L ++ + +A ++ IK+ D + +A + +++ P
Sbjct: 121 RCSK-PICDLISDMGNL---VHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTP--- 173
Query: 147 NVLVVAVMHNCDK-RTLQNDLQDCNNYNSQSLMDAFSCSLDNENRQTDQFSFSINESTEK 205
V + H+ D R QND+ + +D + +S + N +K
Sbjct: 174 --CVSSTDHDSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKK 231
Query: 206 DMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASVCSP-SQLKDDGSIGRDPSMSAITSL 264
N + + N R + + + D L P LKD G + + ++ IT+
Sbjct: 232 IFNQLESIVDFNMSSALTRQSSKMFH-AKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAA 290
Query: 265 TVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSPRTDLGSPNSFSHMSEGILMKKEPA 324
+ +G +N EDL S+ R + FS + ++K+
Sbjct: 291 ---ECLKEEGKTSALTCSLPKN----EDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQ 343
Query: 325 EESTTEE--------SLRSGLPLLLKPDMPNGSGRNNDCERCSDCLVPNEVRADENEGYE 376
E+S + + S L + K D+P+ L+ ++ R D +E
Sbjct: 344 EDSKSLDLKDNDVIQDSSSALHVSSK-DVPSSLSCLPASGSMCGSLIESKARGDFLPQHE 402
Query: 377 HEETLGTT-----EFLNMT----EHFSESQDMTNWKLTKL------NEMNDSQVNEEKEK 421
H++ + E N E F E+ + K + M D +++ ++
Sbjct: 403 HKDNIQDAVTIHEEIQNSVVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQT- 461
Query: 422 FLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDSY 481
+ + E +G V + GL GT + ES +C I+T ++N + Y
Sbjct: 462 ---VIRAESLDGGDTSSTVVESQEGLS--GTHVPESSDC-CEGFINTFSSNDMDGQDLDY 515
Query: 482 GMQDPGVSFVPKTLPSKEDS-VTE-----------EKEIEESKSECYSNIYEQRGNEATE 529
D G P ++ D+ +TE E+ + +SKS+ N + +G +
Sbjct: 516 FNIDEGAKSGPLISDAELDAFLTEQYLQTTNIKSFEENVNDSKSQM--NQIDMKGLDDGN 573
Query: 530 GSGLLLNS-TGDLMKKNYLHNFCSQVPSV--------LGQSSP-KVVASLPSI------- 572
+ + N+ G + + + ++ C V LG+ S V LP+
Sbjct: 574 INNIYFNAEAGAIGESHGINIICETVDKQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQ 633
Query: 573 -------SVPFGGARPKQPSNLKLQIPKPLSDHLQNDFPANSGNNTKNKNDILGKAKLGE 625
S GGARPKQ +L + + D + D P + + ++ +
Sbjct: 634 LSVSDINSQSVGGARPKQLFSLPSRT-RSSKDLNKPDVPDTIESEPSTADTVVPITCAID 692
Query: 626 NSATNVCSPSLGNISNVDTNGEHLESYEAEISTRPCLALAPDSPDNDLRAGQFGISARKP 685
++A S + N ++++N E S+ A P+N + G
Sbjct: 693 STADPQVSFN-SNYIDIESNSEGGSSFVT--------ANEDSVPENTCKEG--------- 734
Query: 686 FTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRK 745
LG+ P WVPDS+APNCM C+ +FTFTKRRHHCRACGKVFC CC+ KCKL Y++ K
Sbjct: 735 -LVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLE-K 792
Query: 746 EARVCVIC------------------------HSVLMNVAQP------------------ 763
EARVCV+C HS QP
Sbjct: 793 EARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQTSSIPSPATLPVS 852
Query: 764 ------------REQRRVWFADGILPNGEVADAAKLTMNGTSSAGTLAVSHD--PVKP 807
+EQ+RVWFADGILPNGEVAD KL S+G+ S D P+ P
Sbjct: 853 ALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKL------SSGSKRCSEDFSPLSP 904
>gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens]
Length = 1430
Score = 84.7 bits (208), Expect = 5e-16
Identities = 37/85 (43%), Positives = 50/85 (58%)
Query: 683 RKPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYM 742
++ + LG AP+W+PD++A CM C + FT T RRHHCRACGK+ C +C S K L Y+
Sbjct: 1206 KEEVSPLGSKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYL 1265
Query: 743 DRKEARVCVICHSVLMNVAQPREQR 767
+ ARVC C L + R
Sbjct: 1266 KNQPARVCEHCFQELQKLDHQHSPR 1290
>gi|189217917 FYVE, RhoGEF and PH domain containing 2 [Homo sapiens]
Length = 655
Score = 75.5 bits (184), Expect = 3e-13
Identities = 41/97 (42%), Positives = 52/97 (53%), Gaps = 7/97 (7%)
Query: 689 LGEVAPVWVPDSQAPNCMKCEARFT-FTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEA 747
LG AP WV D CM+C+ F T+RRHHCRACG V CA C + +L Y D +
Sbjct: 448 LGLRAPQWVRDKMVTMCMRCQEPFNALTRRRHHCRACGYVVCARCSDYRAELKYDDNRPN 507
Query: 748 RVCVICHSVLMNVAQP--REQRRVWFADGILPNGEVA 782
RVC+ C++ L P +E +R GIL G A
Sbjct: 508 RVCLHCYAFLTGNVLPEAKEDKR----RGILEKGSSA 540
>gi|198041928 FYVE, RhoGEF and PH domain containing 4 [Homo sapiens]
Length = 766
Score = 74.3 bits (181), Expect = 7e-13
Identities = 33/81 (40%), Positives = 47/81 (58%), Gaps = 1/81 (1%)
Query: 689 LGEVAPVWVPDSQAPNCMKCEARFT-FTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEA 747
LG+ AP W+ D++ CMKC+ F T+RRHHCRACG V C C K +L Y K +
Sbjct: 549 LGKRAPRWIRDNEVTMCMKCKEPFNALTRRRHHCRACGYVVCWKCSDYKAQLEYDGGKLS 608
Query: 748 RVCVICHSVLMNVAQPREQRR 768
+VC C+ ++ E++R
Sbjct: 609 KVCKDCYQIISGFTDSEEKKR 629
>gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens]
Length = 234
Score = 71.2 bits (173), Expect = 6e-12
Identities = 32/70 (45%), Positives = 40/70 (57%), Gaps = 1/70 (1%)
Query: 694 PVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKE-ARVCVI 752
P WVPD + CM+C+A+F F R+HHCR CGK FC CCS K L M + R C
Sbjct: 39 PQWVPDKECRRCMQCDAKFDFLTRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQCAE 98
Query: 753 CHSVLMNVAQ 762
C V + A+
Sbjct: 99 CALVSLKEAE 108
>gi|13375827 phafin 2 [Homo sapiens]
Length = 249
Score = 70.5 bits (171), Expect = 1e-11
Identities = 33/72 (45%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
Query: 687 TTLGEVAPVWVPDSQAPNCMKCE-ARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRK 745
T E A VWVPDS+A CM+C+ A+FT RRHHCR CG V C C + L K
Sbjct: 140 TPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSK 199
Query: 746 EARVCVICHSVL 757
R+C C+ +L
Sbjct: 200 PVRICDFCYDLL 211
>gi|24797153 faciogenital dysplasia protein [Homo sapiens]
Length = 961
Score = 69.3 bits (168), Expect = 2e-11
Identities = 30/77 (38%), Positives = 44/77 (57%), Gaps = 1/77 (1%)
Query: 685 PFTTLGEVAPVWVPDSQAPNCMKCEARF-TFTKRRHHCRACGKVFCASCCSLKCKLLYMD 743
P LG+ AP + + + CM+C+ F + TKRRHHC+ACG V C C + +L+Y +
Sbjct: 716 PNVDLGKRAPTPIREKEVTMCMRCQEPFNSITKRRHHCKACGHVVCGKCSEFRARLVYDN 775
Query: 744 RKEARVCVICHSVLMNV 760
+ RVC C+ L V
Sbjct: 776 NRSNRVCTDCYVALHGV 792
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 68.9 bits (167), Expect = 3e-11
Identities = 26/75 (34%), Positives = 41/75 (54%), Gaps = 1/75 (1%)
Query: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMD-RKEARVCVICH 754
W+PDSQ C C +FT +RRHHCR CG++FC+ CC+ + +M + R C C
Sbjct: 155 WMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCR 214
Query: 755 SVLMNVAQPREQRRV 769
+ ++ A + +
Sbjct: 215 KIALSYAHSTDSNSI 229
>gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens]
Length = 887
Score = 67.4 bits (163), Expect = 9e-11
Identities = 30/65 (46%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
Query: 691 EVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKL-LYMDRKEARV 749
E P WVPD C C+A FT +R+HHCR+CGK+FC+ C S L Y K RV
Sbjct: 809 EDPPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRV 868
Query: 750 CVICH 754
C C+
Sbjct: 869 CTHCY 873
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 67.4 bits (163), Expect = 9e-11
Identities = 30/69 (43%), Positives = 39/69 (56%), Gaps = 2/69 (2%)
Query: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEARVCVICHS 755
WVPD A +C C+ F KRRHHCR CG VFCA CC L KL D++ ++C+S
Sbjct: 1111 WVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHL--KLPIPDQQLYDPVLVCNS 1168
Query: 756 VLMNVAQPR 764
++ R
Sbjct: 1169 CYEHIQVSR 1177
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 67.0 bits (162), Expect = 1e-10
Identities = 30/68 (44%), Positives = 40/68 (58%), Gaps = 1/68 (1%)
Query: 691 EVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKE-ARV 749
EV W+PD A +C C++ F R+HHCR CG VFC+SCC+ K + E +RV
Sbjct: 1074 EVMTRWLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRV 1133
Query: 750 CVICHSVL 757
C C+S L
Sbjct: 1134 CKSCYSSL 1141
>gi|194018497 FYVE, RhoGEF and PH domain containing 5 [Homo sapiens]
Length = 1462
Score = 65.9 bits (159), Expect = 3e-10
Identities = 36/96 (37%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 663 ALAPDSPDNDLRAGQFGISARKPF-TTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHHC 721
AL D L A + R+ +LGE P VP + CM C F+ T RRHHC
Sbjct: 1205 ALPEDYKAQALAAFHHSVEIRERLGVSLGERPPTLVPVTHVMMCMNCGCDFSLTLRRHHC 1264
Query: 722 RACGKVFCASCCSLKCKLLYMDRKEARVCVICHSVL 757
ACGK+ C +C K L Y+ + A+VC C L
Sbjct: 1265 HACGKIVCRNCSRNKYPLKYLKDRMAKVCDGCFGEL 1300
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 65.5 bits (158), Expect = 3e-10
Identities = 28/63 (44%), Positives = 38/63 (60%), Gaps = 1/63 (1%)
Query: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKE-ARVCVICH 754
W+PD A +C C++ F R+HHCR CG VFC+SCC+ K + E +RVC C+
Sbjct: 1116 WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCY 1175
Query: 755 SVL 757
S L
Sbjct: 1176 SSL 1178
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 65.5 bits (158), Expect = 3e-10
Identities = 27/64 (42%), Positives = 40/64 (62%), Gaps = 1/64 (1%)
Query: 695 VWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEARVCVICH 754
VW+ D +A +C CE F+ +KR+HHCR CG++FC +C + L K RVC CH
Sbjct: 571 VWLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELP-LPSSPKPVRVCDSCH 629
Query: 755 SVLM 758
++L+
Sbjct: 630 ALLI 633
>gi|153791377 apoptosis-inducing protein D [Homo sapiens]
Length = 279
Score = 65.5 bits (158), Expect = 3e-10
Identities = 36/91 (39%), Positives = 47/91 (51%), Gaps = 6/91 (6%)
Query: 677 QFGISARKPFTTLGEVAPVWVPDSQAPNCMKC-EARFTFTKRRHHCRACGKVFCASCCSL 735
Q + R P T E A W+PD CM+C + RF+ RRHHCR CG V CA C
Sbjct: 133 QLRATGRPPST---EHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQ 189
Query: 736 KCKLLYMDRKEARVCVICHSVLMNVAQPREQ 766
+ L + K RVC +C+ L AQ R++
Sbjct: 190 RFLLPRLSPKPVRVCSLCYREL--AAQQRQE 218
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 64.7 bits (156), Expect = 6e-10
Identities = 26/63 (41%), Positives = 40/63 (63%), Gaps = 1/63 (1%)
Query: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEARVCVICHS 755
W+ D +A +C +CE F+ ++R+HHCR CG +FC +C S + L K RVC CH+
Sbjct: 531 WLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYP-KPVRVCDSCHT 589
Query: 756 VLM 758
+L+
Sbjct: 590 LLL 592
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 64.7 bits (156), Expect = 6e-10
Identities = 26/63 (41%), Positives = 40/63 (63%), Gaps = 1/63 (1%)
Query: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEARVCVICHS 755
W+ D +A +C +CE F+ ++R+HHCR CG +FC +C S + L K RVC CH+
Sbjct: 531 WLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYP-KPVRVCDSCHT 589
Query: 756 VLM 758
+L+
Sbjct: 590 LLL 592
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 64.7 bits (156), Expect = 6e-10
Identities = 26/63 (41%), Positives = 40/63 (63%), Gaps = 1/63 (1%)
Query: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEARVCVICHS 755
W+ D +A +C +CE F+ ++R+HHCR CG +FC +C S + L K RVC CH+
Sbjct: 639 WLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYP-KPVRVCDSCHT 697
Query: 756 VLM 758
+L+
Sbjct: 698 LLL 700
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 64.7 bits (156), Expect = 6e-10
Identities = 29/62 (46%), Positives = 35/62 (56%), Gaps = 1/62 (1%)
Query: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEARVCVICHS 755
W D++ NCM C F+ T RRHHCR CG +FCA CS K L +K RVC C +
Sbjct: 1349 WAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAE-CSAKNALTPSSKKPVRVCDACFN 1407
Query: 756 VL 757
L
Sbjct: 1408 DL 1409
>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
Length = 1170
Score = 59.3 bits (142), Expect = 2e-08
Identities = 30/77 (38%), Positives = 40/77 (51%), Gaps = 10/77 (12%)
Query: 691 EVAPVWVPDSQAPNCMKCEARFTFTKRRHHCR---------ACGKVFCASCCSLKCKLLY 741
EV W+PD A +C C++ F R+HHCR CG VFC+SCC+ K +
Sbjct: 1074 EVMTRWLPDHLAAHCYACDSAFWLASRKHHCRDTDRVDQTWNCGNVFCSSCCNQKVPVPS 1133
Query: 742 MDRKE-ARVCVICHSVL 757
E +RVC C+S L
Sbjct: 1134 QQLFEPSRVCKSCYSSL 1150
>gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens]
Length = 2539
Score = 58.5 bits (140), Expect = 4e-08
Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Query: 696 WVPDSQAPNCMKC-EARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEARVCVICH 754
WVPD CM C FT RRHHCR CG++ C+SC + K + ARVC C+
Sbjct: 1809 WVPDETESICMVCCREHFTMFNRRHHCRRCGRLVCSSCSTKKMVVEGCRENPARVCDQCY 1868
Query: 755 S 755
S
Sbjct: 1869 S 1869
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens]
Length = 1478
Score = 58.5 bits (140), Expect = 4e-08
Identities = 24/62 (38%), Positives = 37/62 (59%), Gaps = 1/62 (1%)
Query: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEARVCVICHS 755
W+ D++A +C+ C+ F++ RRHHCR CG++FC CC+ + +KE R C C
Sbjct: 1170 WLGDTEANHCLDCKREFSWMVRRHHCRICGRIFCYYCCNNYVLSKHGGKKE-RCCRACFQ 1228
Query: 756 VL 757
L
Sbjct: 1229 KL 1230
>gi|4758528 hepatocyte growth factor-regulated tyrosine kinase
substrate [Homo sapiens]
Length = 777
Score = 57.8 bits (138), Expect = 7e-08
Identities = 29/73 (39%), Positives = 38/73 (52%), Gaps = 4/73 (5%)
Query: 691 EVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKL-LYMDRKEARV 749
E AP WV A C +C +F R+HHCRACG++FC C S + + KE RV
Sbjct: 155 ERAPDWV---DAEECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRV 211
Query: 750 CVICHSVLMNVAQ 762
C C+ L A+
Sbjct: 212 CEPCYEQLNRKAE 224
>gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Homo
sapiens]
Length = 281
Score = 57.4 bits (137), Expect = 9e-08
Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMD-RKEARVCVICH 754
WV D +C C RF+ T+RRHHCR CG++FC C + ++ + RVC C+
Sbjct: 206 WVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 57.4 bits (137), Expect = 9e-08
Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMD-RKEARVCVICH 754
WV D +C C RF+ T+RRHHCR CG++FC C + ++ + RVC C+
Sbjct: 3451 WVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 3510
>gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform 1
[Homo sapiens]
Length = 1170
Score = 57.0 bits (136), Expect = 1e-07
Identities = 27/65 (41%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 694 PVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMD-RKEARVCVI 752
P W S C +C ARF T R+HHCR CG++ C C + + ++ D K RVC I
Sbjct: 1103 PPWCDGSY---CYECTARFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNI 1159
Query: 753 CHSVL 757
C VL
Sbjct: 1160 CFDVL 1164
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,635,699
Number of Sequences: 37866
Number of extensions: 2712307
Number of successful extensions: 7428
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 51
Number of HSP's that attempted gapping in prelim test: 7270
Number of HSP's gapped (non-prelim): 194
length of query: 1366
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1251
effective length of database: 13,892,928
effective search space: 17380052928
effective search space used: 17380052928
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.