Search of human proteins with 4759310

Search of human proteins with 4759310

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4759310 bestrophin 1 isoform 1 [Homo sapiens]
         (585 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4759310 bestrophin 1 isoform 1 [Homo sapiens]                     1206   0.0  
gi|212720889 bestrophin 1 isoform 2 [Homo sapiens]                   1079   0.0  
gi|115527104 vitelliform macular dystrophy 2-like 3 isoform 1 [H...   512   e-145
gi|119703742 vitelliform macular dystrophy 2-like 1 [Homo sapiens]    499   e-141
gi|23397576 bestrophin 4 [Homo sapiens]                               459   e-129
gi|115527106 vitelliform macular dystrophy 2-like 3 isoform 2 [H...   184   2e-46
gi|224451082 cytospin A [Homo sapiens]                                 36   0.086
gi|224451080 cytospin A [Homo sapiens]                                 36   0.086
gi|50345877 arginyltransferase 1 isoform 1 [Homo sapiens]              36   0.086
gi|61675704 hypothetical protein LOC347487 [Homo sapiens]              35   0.15 
gi|119220605 ubiquitin specific protease 10 [Homo sapiens]             35   0.15 
gi|157785645 SPEG complex locus [Homo sapiens]                         34   0.33 
gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ...    32   1.2  
gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ...    32   1.2  
gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ...    32   1.2  
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ...    32   1.2  
gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ...    32   1.2  
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]        31   3.6  
gi|27886651 potassium voltage-gated channel, subfamily H, member...    30   4.7  
gi|150170670 piccolo isoform 2 [Homo sapiens]                          30   8.0  
gi|150378539 piccolo isoform 1 [Homo sapiens]                          30   8.0  
gi|24307933 transcription factor EB [Homo sapiens]                     30   8.0  

>gi|4759310 bestrophin 1 isoform 1 [Homo sapiens]
          Length = 585

 Score = 1206 bits (3120), Expect = 0.0
 Identities = 585/585 (100%), Positives = 585/585 (100%)

Query: 1   MTITYTSQVANARLGSFSRLLLCWRGSIYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQL 60
           MTITYTSQVANARLGSFSRLLLCWRGSIYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQL
Sbjct: 1   MTITYTSQVANARLGSFSRLLLCWRGSIYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQL 60

Query: 61  MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ 120
           MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ
Sbjct: 61  MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ 120

Query: 121 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM 180
           GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM
Sbjct: 121 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM 180

Query: 181 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV 240
           FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV
Sbjct: 181 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV 240

Query: 241 TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGE 300
           TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGE
Sbjct: 241 TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGE 300

Query: 301 DDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFM 360
           DDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFM
Sbjct: 301 DDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFM 360

Query: 361 GSTFNISLNKEEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESL 420
           GSTFNISLNKEEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESL
Sbjct: 361 GSTFNISLNKEEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESL 420

Query: 421 LHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFP 480
           LHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFP
Sbjct: 421 LHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFP 480

Query: 481 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN 540
           LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN
Sbjct: 481 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN 540

Query: 541 LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRDEAHS 585
           LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRDEAHS
Sbjct: 541 LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRDEAHS 585


>gi|212720889 bestrophin 1 isoform 2 [Homo sapiens]
          Length = 604

 Score = 1079 bits (2790), Expect = 0.0
 Identities = 521/524 (99%), Positives = 521/524 (99%)

Query: 61  MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ 120
           MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ
Sbjct: 1   MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ 60

Query: 121 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM 180
           GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM
Sbjct: 61  GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM 120

Query: 181 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV 240
           FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV
Sbjct: 121 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV 180

Query: 241 TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGE 300
           TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGE
Sbjct: 181 TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGE 240

Query: 301 DDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFM 360
           DDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFM
Sbjct: 241 DDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFM 300

Query: 361 GSTFNISLNKEEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESL 420
           GSTFNISLNKEEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESL
Sbjct: 301 GSTFNISLNKEEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESL 360

Query: 421 LHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFP 480
           LHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFP
Sbjct: 361 LHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFP 420

Query: 481 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN 540
           LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN
Sbjct: 421 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN 480

Query: 541 LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRDEAH 584
           LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENR   H
Sbjct: 481 LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRSVLH 524


>gi|115527104 vitelliform macular dystrophy 2-like 3 isoform 1 [Homo
           sapiens]
          Length = 668

 Score =  512 bits (1319), Expect = e-145
 Identities = 248/414 (59%), Positives = 302/414 (72%), Gaps = 5/414 (1%)

Query: 1   MTITYTSQVANARLGSFSRLLLCWRGSIYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQL 60
           MT+TY+S+VANA    F RLLL WRGSIYKLLY EF++F + Y  I  +YRL LT  Q+ 
Sbjct: 1   MTVTYSSKVANATFFGFHRLLLKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGVQKR 60

Query: 61  MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ 120
            FEKL++YCD Y + IP++FVLGFYVTLVV RWWNQ+ NLPWPDRLM L+S  V G DE 
Sbjct: 61  YFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISSSVHGSDEH 120

Query: 121 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM 180
           GRLLRRTL+RY NL ++LI RSVSTAVYKRFP+  H+V+AGFMT  E K    L  PH  
Sbjct: 121 GRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTTDERKLFNHLKSPHLK 180

Query: 181 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV 240
           +WVP++WF NL+ KA   GRIRD + LQSL+ EMN  R+ C  L+ YDW+ IPLVYTQVV
Sbjct: 181 YWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYTQVV 240

Query: 241 TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGE 300
           T+AVY+FF  CL+GRQFL+P K Y GH+LDL +P+FT LQFFFY GWLKVAEQLINPFGE
Sbjct: 241 TLAVYTFFFACLIGRQFLDPTKGYAGHDLDLYIPIFTLLQFFFYAGWLKVAEQLINPFGE 300

Query: 301 DDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFM 360
           DDDDFETNW +DRNLQVSLLAVDEMH  LP+M+ D+YW+    +PPYT A+A +   SF+
Sbjct: 301 DDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARPPYTLAAADYCIPSFL 360

Query: 361 GSTFNISLNKEEM---EFQPNQEDEEDAHAGI--IGRFLGLQSHDHHPPRANSR 409
           GST  + L+  +    E+  + E     H+ I  + RFL    H   P R + R
Sbjct: 361 GSTVQMGLSGSDFPDEEWLWDYEKHGHRHSMIRRVKRFLSAHEHPSSPRRRSYR 414


>gi|119703742 vitelliform macular dystrophy 2-like 1 [Homo sapiens]
          Length = 509

 Score =  499 bits (1286), Expect = e-141
 Identities = 240/377 (63%), Positives = 296/377 (78%), Gaps = 1/377 (0%)

Query: 1   MTITYTSQVANARLGSFSRLLLCWRGSIYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQL 60
           MT+TYT++VANAR G FS+LLL WRGSIYKLL+ E L FL  Y  +   YR  LTE Q+ 
Sbjct: 1   MTVTYTARVANARFGGFSQLLLLWRGSIYKLLWRELLCFLGFYMALSAAYRFVLTEGQKR 60

Query: 61  MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ 120
            FEKL +YCD Y  LIP+SFVLGFYVTLVV RWW+QY  +P PD LM +V+G V G+D++
Sbjct: 61  YFEKLVIYCDQYASLIPVSFVLGFYVTLVVNRWWSQYLCMPLPDALMCVVAGTVHGRDDR 120

Query: 121 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM 180
           GRL RRTL+RYA L  VLILRSVSTAV+KRFP+  H+V+AGFMT  E K+ E L+  +N 
Sbjct: 121 GRLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFENLNSSYNK 180

Query: 181 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV 240
           +WVP VWF+NL+ +A   GRIRD   L+ LL E+N  R +CG L+ YDWIS+PLVYTQVV
Sbjct: 181 YWVPCVWFSNLAAQARREGRIRDNSALKLLLEELNVFRGKCGMLFHYDWISVPLVYTQVV 240

Query: 241 TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGE 300
           T+A+YS+FL CL+GRQFL+PA+ Y  H+LDL VP+FT LQFFFY GWLKVAEQLINPFGE
Sbjct: 241 TIALYSYFLACLIGRQFLDPAQGYKDHDLDLCVPIFTLLQFFFYAGWLKVAEQLINPFGE 300

Query: 301 DDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASA-QFRRASF 359
           DDDDFETN+++DRN QVS+LAVDEM+ DL  +E D+YW+  E + PYTAA+  Q R+ SF
Sbjct: 301 DDDDFETNFLIDRNFQVSMLAVDEMYDDLAVLEKDLYWDAAEARAPYTAATVFQLRQPSF 360

Query: 360 MGSTFNISLNKEEMEFQ 376
            GSTF+I+L KE+M+FQ
Sbjct: 361 QGSTFDITLAKEDMQFQ 377


>gi|23397576 bestrophin 4 [Homo sapiens]
          Length = 473

 Score =  459 bits (1182), Expect = e-129
 Identities = 235/418 (56%), Positives = 295/418 (70%), Gaps = 22/418 (5%)

Query: 1   MTITYTSQVANARLGSFSRLLLCWRGSIYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQL 60
           MT++YT +VA AR G FS LLL WRGSIYKLLY EFL+F   Y ++   YRL LT+EQ+ 
Sbjct: 1   MTVSYTLKVAEARFGGFSGLLLRWRGSIYKLLYKEFLLFGALYAVLSITYRLLLTQEQRY 60

Query: 61  MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ 120
           ++ ++  YC+    LIP+SFVLGFYVTLVV RWW+QY ++P PD+LM ++S  V G D++
Sbjct: 61  VYAQVARYCNRSADLIPLSFVLGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQR 120

Query: 121 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM 180
           GRLLRRTLIRYANL +VL+LRSVST V KRFP+ +H+V AGFM+  E K+ E L    N 
Sbjct: 121 GRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESLKSDFNK 180

Query: 181 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV 240
           +WVP VWF NL+ +A   GRIRD I L  LL E+N  R +C  L+ YDWISIPLVYTQVV
Sbjct: 181 YWVPCVWFTNLAAQARRDGRIRDDIALCLLLEELNKYRAKCSMLFHYDWISIPLVYTQVV 240

Query: 241 TVAVYSFFLTCLVGRQFLNPAKA--------YPGHE-------LDLVVPVFTFLQFFFYV 285
           T+AVYSFF   LVGRQF+ P            PG E        D+ VP+ T LQFFFY 
Sbjct: 241 TIAVYSFFALSLVGRQFVEPEAGAAKPQKLLKPGQEPAPALGDPDMYVPLTTLLQFFFYA 300

Query: 286 GWLKVAEQLINPFGEDDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQP 345
           GWLKVAEQ+INPFGEDDDDFETN ++DRNLQVSLL+VDEM+Q+LP  E D YW++ +PQP
Sbjct: 301 GWLKVAEQIINPFGEDDDDFETNQLIDRNLQVSLLSVDEMYQNLPPAEKDQYWDEDQPQP 360

Query: 346 PYT-AASAQFRRASFMGSTFNISLNKE-----EMEFQPNQ-EDEEDAHAGIIGRFLGL 396
           PYT A +A+  R SF+GSTFN+ ++ +     ++E  P        A   ++GRFLG+
Sbjct: 361 PYTVATAAESLRPSFLGSTFNLRMSDDPEQSLQVEASPGSGRPAPAAQTPLLGRFLGV 418


>gi|115527106 vitelliform macular dystrophy 2-like 3 isoform 2 [Homo
           sapiens]
          Length = 455

 Score =  184 bits (467), Expect = 2e-46
 Identities = 105/252 (41%), Positives = 131/252 (51%), Gaps = 56/252 (22%)

Query: 163 MTPAEHKQLEKLSLPHNMFWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCG 222
           MT  E K    L  PH  +WVP++WF NL+ KA   GRIRD + LQSL+ EMN  R+ C 
Sbjct: 1   MTTDERKLFNHLKSPHLKYWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCS 60

Query: 223 HLYAYDWISIPLVYTQVVTVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFF 282
            L+ YDW+ IPLVYTQ                                            
Sbjct: 61  LLFGYDWVGIPLVYTQ-------------------------------------------- 76

Query: 283 FYVGWLKVAEQLINPFGEDDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPE 342
                  VAEQLINPFGEDDDDFETNW +DRNLQVSLLAVDEMH  LP+M+ D+YW+   
Sbjct: 77  -------VAEQLINPFGEDDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSA 129

Query: 343 PQPPYTAASAQFRRASFMGSTFNISLNKEEM---EFQPNQEDEEDAHAGI--IGRFLGLQ 397
            +PPYT A+A +   SF+GST  + L+  +    E+  + E     H+ I  + RFL   
Sbjct: 130 ARPPYTLAAADYCIPSFLGSTVQMGLSGSDFPDEEWLWDYEKHGHRHSMIRRVKRFLSAH 189

Query: 398 SHDHHPPRANSR 409
            H   P R + R
Sbjct: 190 EHPSSPRRRSYR 201


>gi|224451082 cytospin A [Homo sapiens]
          Length = 1117

 Score = 36.2 bits (82), Expect = 0.086
 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 1/58 (1%)

Query: 450 VDAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPS-APSKLHSVTGIDTKDKSLKTVS 506
           + +F SA     P   + P+TPLSP+PM  P   + +P + HS++G  +  K L  +S
Sbjct: 845 IKSFDSASQVPNPAAAAIPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTALS 902


>gi|224451080 cytospin A [Homo sapiens]
          Length = 1117

 Score = 36.2 bits (82), Expect = 0.086
 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 1/58 (1%)

Query: 450 VDAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPS-APSKLHSVTGIDTKDKSLKTVS 506
           + +F SA     P   + P+TPLSP+PM  P   + +P + HS++G  +  K L  +S
Sbjct: 845 IKSFDSASQVPNPAAAAIPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTALS 902


>gi|50345877 arginyltransferase 1 isoform 1 [Homo sapiens]
          Length = 518

 Score = 36.2 bits (82), Expect = 0.086
 Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 7/103 (6%)

Query: 391 GRFLGLQSHDHHPPRANSRTKLLWPKR-ESLLHEGLPKN--HKAAKQNVRGQEDNKAWKL 447
           G   G Q+  H P     + K   PK  E L+ E LP+N  HK   + VR    +  +K 
Sbjct: 227 GELEGFQAQGHPPSLFPPKAKSNQPKSLEDLIFESLPENASHKLEVRVVRSSPPSSQFKA 286

Query: 448 KAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFF----PLEPSAP 486
             +++++    YQ   + + P TP       F    PLE   P
Sbjct: 287 TLLESYQVYKRYQMVIHKNPPDTPTESQFTRFLCSSPLEAETP 329


>gi|61675704 hypothetical protein LOC347487 [Homo sapiens]
          Length = 361

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 50/191 (26%), Positives = 81/191 (42%), Gaps = 28/191 (14%)

Query: 403 PPRANSRTKLLWPKR--ESLLHEGLPKNHKAAKQNVRGQED-----NKAWKLKAVDAFKS 455
           P  A   T+  +PKR  +S   + L K+    K + +G  +     + A KL + D    
Sbjct: 149 PNSAGKLTRPSYPKRSSKSSCSKKLSKSSHLEKAHKKGSLEKLCKLDYACKLASSDKPVR 208

Query: 456 APLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFEL 515
            P   +P Y S PQ  +SP+  F P E + P K  +           ++VS G      L
Sbjct: 209 PPQLFKPLYSSHPQNEISPSKPFGPQELAKPPKHFN---------PKRSVSLGRA---AL 256

Query: 516 LSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPLEQSPTNIHTT--LKDHMDP 573
           LS S+ A     E  Q  +K      T  P +  N + E  E++  N+H +  +K     
Sbjct: 257 LSNSELA-----ETCQPYKKKHLVAKTYRPLV--NDISEAKEKNTQNLHVSSKVKSSSRS 309

Query: 574 YWALENRDEAH 584
           +  L++R+ A+
Sbjct: 310 FRKLDSRNNAY 320


>gi|119220605 ubiquitin specific protease 10 [Homo sapiens]
          Length = 798

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 31/119 (26%), Positives = 47/119 (39%), Gaps = 18/119 (15%)

Query: 337 YWNKPEPQPPYTAASAQFRRASFMGSTFN-------ISLNKEEMEFQPNQEDEEDAHAGI 389
           + N P P  P  A   +  R    G+ F        +++NK  +  +  QED E+     
Sbjct: 472 FTNMPVPPKPRQALGDKIVRDIRPGAAFEPTYIYRLLTVNKSSLSEKGRQEDAEE----- 526

Query: 390 IGRFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKA--AKQNVRGQEDNKAWK 446
              +LG   +  H    N + KLL P  E L     PKNH     +Q  +G+     W+
Sbjct: 527 ---YLGFILNGLHEEMLNLK-KLLSPSNEKLTISNGPKNHSVNEEEQEEQGEGSEDEWE 581


>gi|157785645 SPEG complex locus [Homo sapiens]
          Length = 3267

 Score = 34.3 bits (77), Expect = 0.33
 Identities = 35/140 (25%), Positives = 54/140 (38%), Gaps = 18/140 (12%)

Query: 426  PKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPSA 485
            P ++ + K  VRG +D+ A    A    + AP+  RP     P +P S  P   P  P+ 
Sbjct: 2758 PFSNSSEKVFVRGTQDSSAVPSAA---HQEAPVTSRPARARPPDSPTSLAPPLAPAAPTP 2814

Query: 486  PSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFNLTDMP 545
            PS       +     S  T  S A  S +       A+   P+    R + ++      P
Sbjct: 2815 PS-------VTVSPSSPPTPPSQALSSLK-------AVGPPPQTPPRRHRGLQAARPAEP 2860

Query: 546  EIPENHLKEPLEQSPTNIHT 565
             +P  H+  P E  P  + T
Sbjct: 2861 TLPSTHV-TPSEPKPFVLDT 2879


>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
           isoform 1 [Homo sapiens]
          Length = 1599

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 28/161 (17%), Positives = 61/161 (37%), Gaps = 5/161 (3%)

Query: 426 PKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPG-----YYSAPQTPLSPTPMFFP 480
           P+     +    G+    A  ++  D  + A +  RPG     +  +   P SP+P   P
Sbjct: 209 PQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP 268

Query: 481 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN 540
                P    ++  +     ++ T+    ++S  +  E+       PE + +    +E  
Sbjct: 269 SPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVE 328

Query: 541 LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRD 581
           +T    +PE+       Q+PT + +   +  +P   + + D
Sbjct: 329 VTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 369


>gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
           isoform 2 [Homo sapiens]
          Length = 1512

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 28/161 (17%), Positives = 61/161 (37%), Gaps = 5/161 (3%)

Query: 426 PKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPG-----YYSAPQTPLSPTPMFFP 480
           P+     +    G+    A  ++  D  + A +  RPG     +  +   P SP+P   P
Sbjct: 122 PQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP 181

Query: 481 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN 540
                P    ++  +     ++ T+    ++S  +  E+       PE + +    +E  
Sbjct: 182 SPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVE 241

Query: 541 LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRD 581
           +T    +PE+       Q+PT + +   +  +P   + + D
Sbjct: 242 VTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 282


>gi|38201625 eukaryotic translation initiation factor 4 gamma, 1
           isoform 3 [Homo sapiens]
          Length = 1435

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 28/161 (17%), Positives = 61/161 (37%), Gaps = 5/161 (3%)

Query: 426 PKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPG-----YYSAPQTPLSPTPMFFP 480
           P+     +    G+    A  ++  D  + A +  RPG     +  +   P SP+P   P
Sbjct: 45  PQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP 104

Query: 481 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN 540
                P    ++  +     ++ T+    ++S  +  E+       PE + +    +E  
Sbjct: 105 SPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVE 164

Query: 541 LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRD 581
           +T    +PE+       Q+PT + +   +  +P   + + D
Sbjct: 165 VTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 205


>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
           isoform 1 [Homo sapiens]
          Length = 1599

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 28/161 (17%), Positives = 61/161 (37%), Gaps = 5/161 (3%)

Query: 426 PKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPG-----YYSAPQTPLSPTPMFFP 480
           P+     +    G+    A  ++  D  + A +  RPG     +  +   P SP+P   P
Sbjct: 209 PQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP 268

Query: 481 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN 540
                P    ++  +     ++ T+    ++S  +  E+       PE + +    +E  
Sbjct: 269 SPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVE 328

Query: 541 LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRD 581
           +T    +PE+       Q+PT + +   +  +P   + + D
Sbjct: 329 VTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 369


>gi|38201619 eukaryotic translation initiation factor 4 gamma, 1
           isoform 4 [Homo sapiens]
          Length = 1403

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 28/161 (17%), Positives = 61/161 (37%), Gaps = 5/161 (3%)

Query: 426 PKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPG-----YYSAPQTPLSPTPMFFP 480
           P+     +    G+    A  ++  D  + A +  RPG     +  +   P SP+P   P
Sbjct: 13  PQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP 72

Query: 481 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN 540
                P    ++  +     ++ T+    ++S  +  E+       PE + +    +E  
Sbjct: 73  SPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVE 132

Query: 541 LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRD 581
           +T    +PE+       Q+PT + +   +  +P   + + D
Sbjct: 133 VTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 173


>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
          Length = 1488

 Score = 30.8 bits (68), Expect = 3.6
 Identities = 35/167 (20%), Positives = 54/167 (32%), Gaps = 28/167 (16%)

Query: 311  VDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNK 370
            +D  ++ S+++    HQ +P   P      P P   Y +       +SF+GS F     K
Sbjct: 1162 LDSTIEGSVISSPRPHQRMPPPPP------PPPPEEYKSQRPVSNSSSFLGSLFGSKRGK 1215

Query: 371  EEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHK 430
               +  P    +  A +           H HH    +S   L       +L +G  K   
Sbjct: 1216 GPFQMPPPPTGQASASSSSAS---STHHHHHHHHHGHSHGGL------GVLPDGQSKLQA 1266

Query: 431  AAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPM 477
               Q  +G                + P Y  P   S P  P  P P+
Sbjct: 1267 LHAQYCQGPG-------------PAPPPYLPPQQPSLPPPPQQPPPL 1300


>gi|27886651 potassium voltage-gated channel, subfamily H, member 6
           isoform 2 [Homo sapiens]
          Length = 905

 Score = 30.4 bits (67), Expect = 4.7
 Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 11/86 (12%)

Query: 363 TFNISLNKEEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESLLH 422
           TFN+      +   P Q      H G    FL     D  PP + S    LWP+   LL 
Sbjct: 658 TFNLRDAAGGLHSSPRQAPGSQDHQGF---FLSDNQSDAAPPLSISDASGLWPE---LLQ 711

Query: 423 EGLPKNHKAAKQNVRGQEDNKAWKLK 448
           E +P  H         QED   W LK
Sbjct: 712 E-MPPRHSPQSP----QEDPDCWPLK 732


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 29.6 bits (65), Expect = 8.0
 Identities = 31/120 (25%), Positives = 45/120 (37%), Gaps = 21/120 (17%)

Query: 426 PKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFF------ 479
           PK   A KQ++           KA +  K  PL ++P  + +P       P         
Sbjct: 684 PKKDAAPKQDLS----------KAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733

Query: 480 -PLEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVE 538
            P EPS PS+       D K K  K V    K + +L+S S          S+V+ +  E
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMV----KPTTDLVSSSSATTKPDIPSSKVQSQAEE 789


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 29.6 bits (65), Expect = 8.0
 Identities = 31/120 (25%), Positives = 45/120 (37%), Gaps = 21/120 (17%)

Query: 426 PKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFF------ 479
           PK   A KQ++           KA +  K  PL ++P  + +P       P         
Sbjct: 684 PKKDAAPKQDLS----------KAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733

Query: 480 -PLEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVE 538
            P EPS PS+       D K K  K V    K + +L+S S          S+V+ +  E
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMV----KPTTDLVSSSSATTKPDIPSSKVQSQAEE 789


>gi|24307933 transcription factor EB [Homo sapiens]
          Length = 476

 Score = 29.6 bits (65), Expect = 8.0
 Identities = 21/89 (23%), Positives = 35/89 (39%)

Query: 433 KQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSV 492
           ++  + +E  +  + +AV  +      Q+      P TP   TP+ F   P  P ++  V
Sbjct: 13  REQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKV 72

Query: 493 TGIDTKDKSLKTVSSGAKKSFELLSESDG 521
                   S     S  +K  E LSE+ G
Sbjct: 73  QSYLENPTSYHLQQSQHQKVREYLSETYG 101


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,440,135
Number of Sequences: 37866
Number of extensions: 1097341
Number of successful extensions: 3195
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 3171
Number of HSP's gapped (non-prelim): 31
length of query: 585
length of database: 18,247,518
effective HSP length: 108
effective length of query: 477
effective length of database: 14,157,990
effective search space: 6753361230
effective search space used: 6753361230
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.