Guide to the Human Genome
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Search of human proteins with 4759154

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4759154 synaptosomal-associated protein 29 [Homo sapiens]
         (258 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4759154 synaptosomal-associated protein 29 [Homo sapiens]          513   e-146
gi|18765735 synaptosomal-associated protein 25 isoform SNAP25B [...    58   9e-09
gi|18765733 synaptosomal-associated protein 25 isoform SNAP25A [...    56   4e-08
gi|18765729 synaptosomal-associated protein 23 isoform SNAP23A [...    53   3e-07
gi|224465202 synaptosomal-associated protein, 47kDa [Homo sapiens]     40   0.003
gi|4759188 syntaxin 8 [Homo sapiens]                                   38   0.008
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]    38   0.010
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    36   0.038
gi|18765731 synaptosomal-associated protein 23 isoform SNAP23B [...    36   0.038
gi|115511012 coiled-coil domain containing 136 [Homo sapiens]          36   0.038
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s...    34   0.11 
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa...    34   0.11 
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    33   0.19 
gi|5454166 vesicle transport through interaction with t-SNAREs 1...    33   0.19 
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]     33   0.25 
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     33   0.25 
gi|156104874 envoplakin [Homo sapiens]                                 33   0.32 
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        32   0.42 
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        32   0.42 
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         32   0.42 
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         32   0.42 
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                         32   0.42 
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         32   0.42 
gi|41322912 plectin 1 isoform 2 [Homo sapiens]                         32   0.42 
gi|47607492 plectin 1 isoform 1 [Homo sapiens]                         32   0.42 
gi|40538794 coiled-coil domain containing 21 [Homo sapiens]            32   0.42 
gi|238908495 similar to pleckstrin homology domain protein (5V32...    32   0.55 
gi|71061468 centromere protein E [Homo sapiens]                        32   0.55 
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...    32   0.55 
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    32   0.55 

>gi|4759154 synaptosomal-associated protein 29 [Homo sapiens]
          Length = 258

 Score =  513 bits (1320), Expect = e-146
 Identities = 258/258 (100%), Positives = 258/258 (100%)

Query: 1   MSAYPKSYNPFDDDGEDEGARPAPWRDARDLPDGPDAPADRQQYLRQEVLRRAEATAAST 60
           MSAYPKSYNPFDDDGEDEGARPAPWRDARDLPDGPDAPADRQQYLRQEVLRRAEATAAST
Sbjct: 1   MSAYPKSYNPFDDDGEDEGARPAPWRDARDLPDGPDAPADRQQYLRQEVLRRAEATAAST 60

Query: 61  SRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKMDQDLKISQKHINSIKSVFGGLV 120
           SRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKMDQDLKISQKHINSIKSVFGGLV
Sbjct: 61  SRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKMDQDLKISQKHINSIKSVFGGLV 120

Query: 121 NYFKSKPVETPPEQNGTLTSQPNNRLKEAISTSKEQEAKYQASHPNLRKLDDTDPVPRGA 180
           NYFKSKPVETPPEQNGTLTSQPNNRLKEAISTSKEQEAKYQASHPNLRKLDDTDPVPRGA
Sbjct: 121 NYFKSKPVETPPEQNGTLTSQPNNRLKEAISTSKEQEAKYQASHPNLRKLDDTDPVPRGA 180

Query: 181 GSAMSTDAYPKNPHLRAYHQKIDSNLDELSMGLGRLKDIALGMQTEIEEQDDILDRLTTK 240
           GSAMSTDAYPKNPHLRAYHQKIDSNLDELSMGLGRLKDIALGMQTEIEEQDDILDRLTTK
Sbjct: 181 GSAMSTDAYPKNPHLRAYHQKIDSNLDELSMGLGRLKDIALGMQTEIEEQDDILDRLTTK 240

Query: 241 VDKLDVNIKSTERKVRQL 258
           VDKLDVNIKSTERKVRQL
Sbjct: 241 VDKLDVNIKSTERKVRQL 258


>gi|18765735 synaptosomal-associated protein 25 isoform SNAP25B
           [Homo sapiens]
          Length = 206

 Score = 57.8 bits (138), Expect = 9e-09
 Identities = 57/222 (25%), Positives = 99/222 (44%), Gaps = 41/222 (18%)

Query: 47  QEVLRRAEATA----ASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKMDQDL 102
           +E+ RRA+  A     ST R L L+ ES+  G+ +   L  Q   LER E+ +D++++D+
Sbjct: 12  EEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDM 71

Query: 103 KISQKHINSIKSVFGGLV---NYFKSKPVETPP---EQNGTLTSQPNNRLKEAISTSKEQ 156
           K ++K++  +    G  V   N  KS           Q+G + SQP   + E     +EQ
Sbjct: 72  KEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDE-----REQ 126

Query: 157 EAKYQASHPNLRKLDDTDPVPRGAGSAMSTDAYPKNPHLRAYHQKIDSNLDELSMGLGRL 216
            A                 +  G    ++ DA            ++D NL+++S  +G L
Sbjct: 127 MA-----------------ISGGFIRRVTNDAR---------ENEMDENLEQVSGIIGNL 160

Query: 217 KDIALGMQTEIEEQDDILDRLTTKVDKLDVNIKSTERKVRQL 258
           + +AL M  EI+ Q+  +DR+  K D     I    ++  ++
Sbjct: 161 RHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKM 202


>gi|18765733 synaptosomal-associated protein 25 isoform SNAP25A
           [Homo sapiens]
          Length = 206

 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 55/222 (24%), Positives = 98/222 (44%), Gaps = 41/222 (18%)

Query: 47  QEVLRRAEATA----ASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKMDQDL 102
           +E+ RRA+  A     ST R L L+ ES+  G+ +   L  Q   L+R E+ ++ ++QD+
Sbjct: 12  EEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLDRVEEGMNHINQDM 71

Query: 103 KISQKHINSIKSVFGGLV---NYFKSKPVETPP---EQNGTLTSQPNNRLKEAISTSKEQ 156
           K ++K++  +    G  +   N  KS           Q+G + SQP   + E     +EQ
Sbjct: 72  KEAEKNLKDLGKCCGLFICPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDE-----REQ 126

Query: 157 EAKYQASHPNLRKLDDTDPVPRGAGSAMSTDAYPKNPHLRAYHQKIDSNLDELSMGLGRL 216
            A                 +  G    ++ DA            ++D NL+++S  +G L
Sbjct: 127 MA-----------------ISGGFIRRVTNDAR---------ENEMDENLEQVSGIIGNL 160

Query: 217 KDIALGMQTEIEEQDDILDRLTTKVDKLDVNIKSTERKVRQL 258
           + +AL M  EI+ Q+  +DR+  K D     I    ++  ++
Sbjct: 161 RHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKM 202


>gi|18765729 synaptosomal-associated protein 23 isoform SNAP23A
           [Homo sapiens]
          Length = 211

 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 50/201 (24%), Positives = 86/201 (42%), Gaps = 20/201 (9%)

Query: 47  QEVLRRA----EATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKMDQDL 102
           +E+ +RA    + +  ST R L L  ES+  G+ +   L  Q+  L R E+ +D++++D+
Sbjct: 7   EEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDM 66

Query: 103 KISQKHINSIKSVFGGLV-NYFKSKPVETPPEQNGTLTSQPNNRLKEAISTSKEQEAKYQ 161
           + ++K +  +    G  V    ++K  E+      T      N     +S         Q
Sbjct: 67  RETEKTLTELNKCCGLCVCPCNRTKNFESGKAYKTTWGDGGENSPCNVVSKQPGPVTNGQ 126

Query: 162 ASHPNLRKLDDTDPVPRGAGSAMSTDAYPKNPHLRAYHQKIDSNLDELSMGLGRLKDIAL 221
              P             GA S      Y K     A   +++ NL ++   LG LKD+AL
Sbjct: 127 LQQPTT-----------GAASG----GYIKRITNDAREDEMEENLTQVGSILGNLKDMAL 171

Query: 222 GMQTEIEEQDDILDRLTTKVD 242
            +  EI+ Q+  + R+T K D
Sbjct: 172 NIGNEIDAQNPQIKRITDKAD 192



 Score = 29.3 bits (64), Expect = 3.6
 Identities = 16/63 (25%), Positives = 35/63 (55%), Gaps = 3/63 (4%)

Query: 199 HQKIDSNLDELSMGLG---RLKDIALGMQTEIEEQDDILDRLTTKVDKLDVNIKSTERKV 255
           HQ  D +L+     LG     +D  +   T ++EQ + L+R+   +D+++ +++ TE+ +
Sbjct: 14  HQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDMRETEKTL 73

Query: 256 RQL 258
            +L
Sbjct: 74  TEL 76


>gi|224465202 synaptosomal-associated protein, 47kDa [Homo sapiens]
          Length = 464

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 18/56 (32%), Positives = 35/56 (62%)

Query: 203 DSNLDELSMGLGRLKDIALGMQTEIEEQDDILDRLTTKVDKLDVNIKSTERKVRQL 258
           +++  EL+  L R+K +AL  ++E+E QD+ LD +   VD+  + I    R++++L
Sbjct: 408 EADTQELTQILRRMKGLALEAESELERQDEALDGVAAAVDRATLTIDKHNRRMKRL 463



 Score = 28.5 bits (62), Expect = 6.1
 Identities = 26/106 (24%), Positives = 52/106 (49%), Gaps = 7/106 (6%)

Query: 42  QQYLRQEVLRRAEATA-ASTSRS-----LALMYESEKVGVASSEELARQRGVLERTEKMV 95
           + + R+ +L +  A A AS  R+       LM  S+K    ++  L  Q   L+   + +
Sbjct: 140 EHFWRELLLSQPGAVADASVPRTRGEELTGLMAGSQKRLEDTARVLHHQGQQLDSVMRGL 199

Query: 96  DKMDQDLKISQKHINSIKS-VFGGLVNYFKSKPVETPPEQNGTLTS 140
           DKM+ DL+++ + +  ++S  +    +     P ET P ++ ++TS
Sbjct: 200 DKMESDLEVADRLLTELESPAWWPFSSKLWKTPPETKPREDVSMTS 245


>gi|4759188 syntaxin 8 [Homo sapiens]
          Length = 236

 Score = 38.1 bits (87), Expect = 0.008
 Identities = 21/68 (30%), Positives = 37/68 (54%), Gaps = 4/68 (5%)

Query: 195 LRAYHQKI----DSNLDELSMGLGRLKDIALGMQTEIEEQDDILDRLTTKVDKLDVNIKS 250
           +R   QKI    D+ LD LS  + R K +   +  E++EQ++I+D L   V+  D  +++
Sbjct: 140 IRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRN 199

Query: 251 TERKVRQL 258
             R+V  +
Sbjct: 200 ETRRVNMV 207


>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
          Length = 1233

 Score = 37.7 bits (86), Expect = 0.010
 Identities = 47/224 (20%), Positives = 92/224 (41%), Gaps = 11/224 (4%)

Query: 39  ADRQQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKM 98
           ADR Q L+ EV+R      A     L  +Y +E      ++ELA +   +E+ +K +DK+
Sbjct: 206 ADRYQRLKDEVVR------AQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKV 259

Query: 99  DQDLKISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTSQPNNRLKEAISTSKEQEA 158
           + +LK  +K +  +      +    K K  E   ++   + ++ N   K     + ++  
Sbjct: 260 EDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSL 319

Query: 159 KYQASHPNLRKLDDTDPVPRGAGSAMSTDAYPKNPHLRAYHQKIDSNLDELSM-GLGRLK 217
           +    H   RK D  +          +   + +     +  Q  D  L+E  +    RLK
Sbjct: 320 QNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLK 379

Query: 218 DIALGMQTEIEEQDDILDR-LTTKVDKLDVNIK---STERKVRQ 257
           + A      + ++ +  +R      D+LD+  +    TE K++Q
Sbjct: 380 EEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQ 423


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
            sapiens]
          Length = 2363

 Score = 35.8 bits (81), Expect = 0.038
 Identities = 46/230 (20%), Positives = 94/230 (40%), Gaps = 30/230 (13%)

Query: 29   RDLPDGPDAPADRQQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVL 88
            R L    +    R Q L +E+ R      A  +RS A +  ++ +  +  E+L + R   
Sbjct: 1355 RKLLSEKEVHTKRIQQLTEEIGR----LKAEIARSNASLTNNQNLIQSLKEDLNKVRTEK 1410

Query: 89   ERTEKMVDKMDQDLKISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTSQPNNRLKE 148
            E  +K +D    D++   K I  +K +       +K++  E   +Q+            +
Sbjct: 1411 ETIQKDLDAKIIDIQEKVKTITQVKKIG----RRYKTQYEELKAQQD------------K 1454

Query: 149  AISTSKEQEAKYQASHPNLRKLDDTDPVPRGAGSAMSTDAYPKNPHLRAYHQKIDSNLDE 208
             + TS +    +Q  H +++++ +               A  K+  L +  + +   L E
Sbjct: 1455 VMETSAQSSGDHQEQHVSVQEMQELKET--------LNQAETKSKSLESQVENLQKTLSE 1506

Query: 209  LSMGLGRLKDIALGMQTEIEE-QDDILDRLTTKVDKLDVNIKSTERKVRQ 257
                   L++  + +Q+E+   + D+ DR TT+ ++L   I   E K R+
Sbjct: 1507 KETEARNLQEQTVQLQSELSRLRQDLQDR-TTQEEQLRQQITEKEEKTRK 1555


>gi|18765731 synaptosomal-associated protein 23 isoform SNAP23B
           [Homo sapiens]
          Length = 158

 Score = 35.8 bits (81), Expect = 0.038
 Identities = 17/46 (36%), Positives = 28/46 (60%)

Query: 197 AYHQKIDSNLDELSMGLGRLKDIALGMQTEIEEQDDILDRLTTKVD 242
           A   +++ NL ++   LG LKD+AL +  EI+ Q+  + R+T K D
Sbjct: 94  AREDEMEENLTQVGSILGNLKDMALNIGNEIDAQNPQIKRITDKAD 139



 Score = 29.3 bits (64), Expect = 3.6
 Identities = 16/63 (25%), Positives = 35/63 (55%), Gaps = 3/63 (4%)

Query: 199 HQKIDSNLDELSMGLG---RLKDIALGMQTEIEEQDDILDRLTTKVDKLDVNIKSTERKV 255
           HQ  D +L+     LG     +D  +   T ++EQ + L+R+   +D+++ +++ TE+ +
Sbjct: 14  HQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDMRETEKTL 73

Query: 256 RQL 258
            +L
Sbjct: 74  TEL 76


>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
          Length = 1154

 Score = 35.8 bits (81), Expect = 0.038
 Identities = 35/138 (25%), Positives = 61/138 (44%), Gaps = 25/138 (18%)

Query: 40  DRQQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGV-------LERTE 92
           +RQQ L++E L+  EA       ++A   ES +    +  +L   + +       LER +
Sbjct: 441 ERQQQLQEE-LQCHEAELQHLRDTVASFKESNEKDTETHAQLQEMKQLYQASKDELERQK 499

Query: 93  KMVDKMDQDLKISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTSQPNNRLKEAIST 152
            M D+++QDL + Q  +  +K+          S P+   PE  G       N+    +S 
Sbjct: 500 HMYDQLEQDLLLCQLELKELKA----------SHPI---PEDKGKCA----NKCDTLLSR 542

Query: 153 SKEQEAKYQASHPNLRKL 170
             E + KY+AS   + +L
Sbjct: 543 LTELQEKYKASQKEMGQL 560


>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
            sapiens]
          Length = 3118

 Score = 34.3 bits (77), Expect = 0.11
 Identities = 37/195 (18%), Positives = 82/195 (42%), Gaps = 41/195 (21%)

Query: 85   RGVLERTEKMVD---KMDQDLKISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTSQ 141
            +G L+++ ++++   K+  D+K ++ H+N +K+             +E    +NG L   
Sbjct: 1968 KGCLQKSFRILNEAKKLANDVKENEDHLNGLKT------------RIENADARNGDLLRT 2015

Query: 142  PNNRLKEAISTSKEQEAKYQASHPNLRKLDDT---------------DPVPRG----AGS 182
             N+ L +  +   +  AK QA     R+ +DT               D + +     A S
Sbjct: 2016 LNDTLGKLSAIPNDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADS 2075

Query: 183  AMSTDAYPKNPHLR-------AYHQKIDSNLDELSMGLGRLKDIALGMQTEIEEQDDILD 235
               T+A  K+P          A  + ++   D L   L  +K++   ++  I E  ++++
Sbjct: 2076 VAKTNAVVKDPSKNKIIADADATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELIN 2135

Query: 236  RLTTKVDKLDVNIKS 250
            +   + + + V++ S
Sbjct: 2136 QARKQANSIKVSVSS 2150


>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
            sapiens]
          Length = 3122

 Score = 34.3 bits (77), Expect = 0.11
 Identities = 37/195 (18%), Positives = 82/195 (42%), Gaps = 41/195 (21%)

Query: 85   RGVLERTEKMVD---KMDQDLKISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTSQ 141
            +G L+++ ++++   K+  D+K ++ H+N +K+             +E    +NG L   
Sbjct: 1968 KGCLQKSFRILNEAKKLANDVKENEDHLNGLKT------------RIENADARNGDLLRT 2015

Query: 142  PNNRLKEAISTSKEQEAKYQASHPNLRKLDDT---------------DPVPRG----AGS 182
             N+ L +  +   +  AK QA     R+ +DT               D + +     A S
Sbjct: 2016 LNDTLGKLSAIPNDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADS 2075

Query: 183  AMSTDAYPKNPHLR-------AYHQKIDSNLDELSMGLGRLKDIALGMQTEIEEQDDILD 235
               T+A  K+P          A  + ++   D L   L  +K++   ++  I E  ++++
Sbjct: 2076 VAKTNAVVKDPSKNKIIADADATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELIN 2135

Query: 236  RLTTKVDKLDVNIKS 250
            +   + + + V++ S
Sbjct: 2136 QARKQANSIKVSVSS 2150


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
           sapiens]
          Length = 1935

 Score = 33.5 bits (75), Expect = 0.19
 Identities = 42/183 (22%), Positives = 77/183 (42%), Gaps = 21/183 (11%)

Query: 82  ARQRGVLERTE--KMVDKMDQDLKISQKHINSIKSV--FGGLVNYFKSKPVETPPEQNGT 137
           A+ RGVL R E  K++++ D  L + Q +I +   V  +  +  YFK KP+    E+   
Sbjct: 790 AQSRGVLARMEYKKLLERRDS-LLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKE 848

Query: 138 LTSQPNN--RLKEAISTSKEQEAKYQASHPNLRKLDDTDPVPRGAGSAMSTDAYPKNPHL 195
           + S      RLKEA+  S+ +  + +    +L +  +   +   A      DA       
Sbjct: 849 MASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADA------- 901

Query: 196 RAYHQKIDSNLDELSMGLGRLKDIALGMQTEIEEQDDILDRLTTKVDKLDVNIKSTERKV 255
                  +   D+L     +L+     M   +E+++++   LT K  KL+      +R +
Sbjct: 902 -------EERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 954

Query: 256 RQL 258
             L
Sbjct: 955 DDL 957



 Score = 30.0 bits (66), Expect = 2.1
 Identities = 34/187 (18%), Positives = 74/187 (39%), Gaps = 28/187 (14%)

Query: 80   ELARQRGVLERTEKMVDKMDQDLKISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLT 139
            EL   R V+E+TE+     +Q+L  + + +  + S    L+N  K    +          
Sbjct: 1684 ELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDAD---------L 1734

Query: 140  SQPNNRLKEAISTSKEQEAKYQASHPNLRKLDDTDPVPRGAGSAMSTDAYPKNPHLRAYH 199
            SQ    ++EA+   +  E K +      + + D   +         T A     HL    
Sbjct: 1735 SQLQTEVEEAVQECRNAEEKAK------KAITDAAMMAEELKKEQDTSA-----HLERMK 1783

Query: 200  QKIDSNLDELSMGLGRLKDIAL--------GMQTEIEEQDDILDRLTTKVDKLDVNIKST 251
            + ++  + +L   L   + IAL         ++  + E ++ L+    +  +    ++ +
Sbjct: 1784 KNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKS 1843

Query: 252  ERKVRQL 258
            ER++++L
Sbjct: 1844 ERRIKEL 1850


>gi|5454166 vesicle transport through interaction with t-SNAREs 1B
           [Homo sapiens]
          Length = 232

 Score = 33.5 bits (75), Expect = 0.19
 Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 40  DRQQYLRQEVLRRAEATAASTS---RSLALMYESEKVGVASSEELARQRGVLERTEKMVD 96
           +R Q  R  +L+  E+   +T    RS  +  E++++G    EEL  QR  LERT+  + 
Sbjct: 123 NRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSRLV 182

Query: 97  KMDQDLKISQKHINSI 112
              ++L  S+K + S+
Sbjct: 183 NTSENLSKSRKILRSM 198


>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
          Length = 3664

 Score = 33.1 bits (74), Expect = 0.25
 Identities = 22/109 (20%), Positives = 49/109 (44%), Gaps = 10/109 (9%)

Query: 41   RQQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKMDQ 100
            + + + +E L+R+ +      + L L  E+EK+   +S+  A            ++  + 
Sbjct: 1843 KSERIDREKLKRSNSPRGEAQKLLELKMEAEKITRTASKNSAAD----------LEHPEP 1892

Query: 101  DLKISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTSQPNNRLKEA 149
             L +S+    +++SV+  + ++    PV+ P EQ      +    L+EA
Sbjct: 1893 SLPLSRTRRRNVRSVYATMGDHENRSPVKEPVEQPRVTRKRLERELQEA 1941


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 33.1 bits (74), Expect = 0.25
 Identities = 41/193 (21%), Positives = 79/193 (40%), Gaps = 51/193 (26%)

Query: 69  ESEKVGVASSEELARQRGVLERTEKMVDKMDQDLKISQKHINSIKSVFGGLVNYFKSKPV 128
           E EK  +   +E+  Q  + E  EK ++K+D    + Q  + S+ S    ++        
Sbjct: 650 EQEKETLLKDKEIIFQAHIEEMNEKTLEKLD----VKQTELESLSSELSEVL-------- 697

Query: 129 ETPPEQNGTLTSQPNNRLKEAISTSKEQEAKYQASHPNLRKLDDTDPVPRGAGSAMSTDA 188
                       +  ++L+E +S  K+Q  K +       K+D+                
Sbjct: 698 ------------KARHKLEEELSVLKDQTDKMKQELE--AKMDEQ--------------- 728

Query: 189 YPKNPHLRAYHQKIDSNLDELSMGLGR----LKDIALGMQTEIEEQDDILDRLTTKVDKL 244
             KN H     Q++DS + E  + + R    LKD    ++  ++E+D  L      V+ L
Sbjct: 729 --KNHH----QQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENL 782

Query: 245 DVNIKSTERKVRQ 257
           + +IK +E +++Q
Sbjct: 783 EADIKRSEGELQQ 795


>gi|156104874 envoplakin [Homo sapiens]
          Length = 2033

 Score = 32.7 bits (73), Expect = 0.32
 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 11/71 (15%)

Query: 191  KNPHLRAYHQKIDSNLDELSMGLGRLKDIALGMQ---TEIEEQDDILDRLTTKVDKLDVN 247
            K+P LR  H ++  +LDE    +GR + + L +Q     +EEQ+ +L     +  KL V 
Sbjct: 1380 KDPKLREEHSRLSGSLDE---EVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAV- 1435

Query: 248  IKSTERKVRQL 258
                ER++RQL
Sbjct: 1436 ----ERELRQL 1442


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 32.3 bits (72), Expect = 0.42
 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 24/106 (22%)

Query: 76   ASSEELARQRGVLERTEKMVDKMDQDLKISQKHINSIKSVFGGLVNYFK-----SKPVET 130
            A  E+L +++ +LE  E+  +K+++  + ++++IN+IK     LV Y       + P + 
Sbjct: 1243 AVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKK 1302

Query: 131  PPEQNG-------------------TLTSQPNNRLKEAISTSKEQE 157
            P  Q+G                   TLTSQ    + E +   +E+E
Sbjct: 1303 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEE 1348



 Score = 32.0 bits (71), Expect = 0.55
 Identities = 15/77 (19%), Positives = 42/77 (54%)

Query: 42   QQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKMDQD 101
            QQ +++EV+RR EA   +  +  ++  E +++  +S  E+  +    E  E+   +++++
Sbjct: 1394 QQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEE 1453

Query: 102  LKISQKHINSIKSVFGG 118
            +++ +  + + +   GG
Sbjct: 1454 IRVVRLQLEATERQRGG 1470



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 29/133 (21%), Positives = 59/133 (44%), Gaps = 10/133 (7%)

Query: 39   ADRQQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKM 98
            A RQ+ L  E  RR         +SLA   E+ +   A+ EE+ R +  +E   ++ ++ 
Sbjct: 1969 AARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERA 2028

Query: 99   DQD--------LKISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTSQPNNRLKEAI 150
            +Q+         + +QK + + +      V   K + ++   +Q  ++  Q     + A 
Sbjct: 2029 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ-KEQELQQTLQQEQSVLDQLRGEAEAAR 2087

Query: 151  STSKE-QEAKYQA 162
              ++E +EA+ QA
Sbjct: 2088 RAAEEAEEARVQA 2100


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 32.3 bits (72), Expect = 0.42
 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 24/106 (22%)

Query: 76   ASSEELARQRGVLERTEKMVDKMDQDLKISQKHINSIKSVFGGLVNYFK-----SKPVET 130
            A  E+L +++ +LE  E+  +K+++  + ++++IN+IK     LV Y       + P + 
Sbjct: 1247 AVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKK 1306

Query: 131  PPEQNG-------------------TLTSQPNNRLKEAISTSKEQE 157
            P  Q+G                   TLTSQ    + E +   +E+E
Sbjct: 1307 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEE 1352



 Score = 32.0 bits (71), Expect = 0.55
 Identities = 15/77 (19%), Positives = 42/77 (54%)

Query: 42   QQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKMDQD 101
            QQ +++EV+RR EA   +  +  ++  E +++  +S  E+  +    E  E+   +++++
Sbjct: 1398 QQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEE 1457

Query: 102  LKISQKHINSIKSVFGG 118
            +++ +  + + +   GG
Sbjct: 1458 IRVVRLQLEATERQRGG 1474



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 29/133 (21%), Positives = 59/133 (44%), Gaps = 10/133 (7%)

Query: 39   ADRQQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKM 98
            A RQ+ L  E  RR         +SLA   E+ +   A+ EE+ R +  +E   ++ ++ 
Sbjct: 1973 AARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERA 2032

Query: 99   DQD--------LKISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTSQPNNRLKEAI 150
            +Q+         + +QK + + +      V   K + ++   +Q  ++  Q     + A 
Sbjct: 2033 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ-KEQELQQTLQQEQSVLDQLRGEAEAAR 2091

Query: 151  STSKE-QEAKYQA 162
              ++E +EA+ QA
Sbjct: 2092 RAAEEAEEARVQA 2104


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 32.3 bits (72), Expect = 0.42
 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 24/106 (22%)

Query: 76   ASSEELARQRGVLERTEKMVDKMDQDLKISQKHINSIKSVFGGLVNYFK-----SKPVET 130
            A  E+L +++ +LE  E+  +K+++  + ++++IN+IK     LV Y       + P + 
Sbjct: 1243 AVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKK 1302

Query: 131  PPEQNG-------------------TLTSQPNNRLKEAISTSKEQE 157
            P  Q+G                   TLTSQ    + E +   +E+E
Sbjct: 1303 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEE 1348



 Score = 32.0 bits (71), Expect = 0.55
 Identities = 15/77 (19%), Positives = 42/77 (54%)

Query: 42   QQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKMDQD 101
            QQ +++EV+RR EA   +  +  ++  E +++  +S  E+  +    E  E+   +++++
Sbjct: 1394 QQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEE 1453

Query: 102  LKISQKHINSIKSVFGG 118
            +++ +  + + +   GG
Sbjct: 1454 IRVVRLQLEATERQRGG 1470



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 29/133 (21%), Positives = 59/133 (44%), Gaps = 10/133 (7%)

Query: 39   ADRQQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKM 98
            A RQ+ L  E  RR         +SLA   E+ +   A+ EE+ R +  +E   ++ ++ 
Sbjct: 1969 AARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERA 2028

Query: 99   DQD--------LKISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTSQPNNRLKEAI 150
            +Q+         + +QK + + +      V   K + ++   +Q  ++  Q     + A 
Sbjct: 2029 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ-KEQELQQTLQQEQSVLDQLRGEAEAAR 2087

Query: 151  STSKE-QEAKYQA 162
              ++E +EA+ QA
Sbjct: 2088 RAAEEAEEARVQA 2100


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 32.3 bits (72), Expect = 0.42
 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 24/106 (22%)

Query: 76   ASSEELARQRGVLERTEKMVDKMDQDLKISQKHINSIKSVFGGLVNYFK-----SKPVET 130
            A  E+L +++ +LE  E+  +K+++  + ++++IN+IK     LV Y       + P + 
Sbjct: 1211 AVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKK 1270

Query: 131  PPEQNG-------------------TLTSQPNNRLKEAISTSKEQE 157
            P  Q+G                   TLTSQ    + E +   +E+E
Sbjct: 1271 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEE 1316



 Score = 32.0 bits (71), Expect = 0.55
 Identities = 15/77 (19%), Positives = 42/77 (54%)

Query: 42   QQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKMDQD 101
            QQ +++EV+RR EA   +  +  ++  E +++  +S  E+  +    E  E+   +++++
Sbjct: 1362 QQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEE 1421

Query: 102  LKISQKHINSIKSVFGG 118
            +++ +  + + +   GG
Sbjct: 1422 IRVVRLQLEATERQRGG 1438



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 29/133 (21%), Positives = 59/133 (44%), Gaps = 10/133 (7%)

Query: 39   ADRQQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKM 98
            A RQ+ L  E  RR         +SLA   E+ +   A+ EE+ R +  +E   ++ ++ 
Sbjct: 1937 AARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERA 1996

Query: 99   DQD--------LKISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTSQPNNRLKEAI 150
            +Q+         + +QK + + +      V   K + ++   +Q  ++  Q     + A 
Sbjct: 1997 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ-KEQELQQTLQQEQSVLDQLRGEAEAAR 2055

Query: 151  STSKE-QEAKYQA 162
              ++E +EA+ QA
Sbjct: 2056 RAAEEAEEARVQA 2068


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score = 32.3 bits (72), Expect = 0.42
 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 24/106 (22%)

Query: 76   ASSEELARQRGVLERTEKMVDKMDQDLKISQKHINSIKSVFGGLVNYFK-----SKPVET 130
            A  E+L +++ +LE  E+  +K+++  + ++++IN+IK     LV Y       + P + 
Sbjct: 1380 AVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKK 1439

Query: 131  PPEQNG-------------------TLTSQPNNRLKEAISTSKEQE 157
            P  Q+G                   TLTSQ    + E +   +E+E
Sbjct: 1440 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEE 1485



 Score = 32.0 bits (71), Expect = 0.55
 Identities = 15/77 (19%), Positives = 42/77 (54%)

Query: 42   QQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKMDQD 101
            QQ +++EV+RR EA   +  +  ++  E +++  +S  E+  +    E  E+   +++++
Sbjct: 1531 QQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEE 1590

Query: 102  LKISQKHINSIKSVFGG 118
            +++ +  + + +   GG
Sbjct: 1591 IRVVRLQLEATERQRGG 1607



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 29/133 (21%), Positives = 59/133 (44%), Gaps = 10/133 (7%)

Query: 39   ADRQQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKM 98
            A RQ+ L  E  RR         +SLA   E+ +   A+ EE+ R +  +E   ++ ++ 
Sbjct: 2106 AARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERA 2165

Query: 99   DQD--------LKISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTSQPNNRLKEAI 150
            +Q+         + +QK + + +      V   K + ++   +Q  ++  Q     + A 
Sbjct: 2166 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ-KEQELQQTLQQEQSVLDQLRGEAEAAR 2224

Query: 151  STSKE-QEAKYQA 162
              ++E +EA+ QA
Sbjct: 2225 RAAEEAEEARVQA 2237


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 32.3 bits (72), Expect = 0.42
 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 24/106 (22%)

Query: 76   ASSEELARQRGVLERTEKMVDKMDQDLKISQKHINSIKSVFGGLVNYFK-----SKPVET 130
            A  E+L +++ +LE  E+  +K+++  + ++++IN+IK     LV Y       + P + 
Sbjct: 1221 AVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKK 1280

Query: 131  PPEQNG-------------------TLTSQPNNRLKEAISTSKEQE 157
            P  Q+G                   TLTSQ    + E +   +E+E
Sbjct: 1281 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEE 1326



 Score = 32.0 bits (71), Expect = 0.55
 Identities = 15/77 (19%), Positives = 42/77 (54%)

Query: 42   QQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKMDQD 101
            QQ +++EV+RR EA   +  +  ++  E +++  +S  E+  +    E  E+   +++++
Sbjct: 1372 QQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEE 1431

Query: 102  LKISQKHINSIKSVFGG 118
            +++ +  + + +   GG
Sbjct: 1432 IRVVRLQLEATERQRGG 1448



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 29/133 (21%), Positives = 59/133 (44%), Gaps = 10/133 (7%)

Query: 39   ADRQQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKM 98
            A RQ+ L  E  RR         +SLA   E+ +   A+ EE+ R +  +E   ++ ++ 
Sbjct: 1947 AARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERA 2006

Query: 99   DQD--------LKISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTSQPNNRLKEAI 150
            +Q+         + +QK + + +      V   K + ++   +Q  ++  Q     + A 
Sbjct: 2007 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ-KEQELQQTLQQEQSVLDQLRGEAEAAR 2065

Query: 151  STSKE-QEAKYQA 162
              ++E +EA+ QA
Sbjct: 2066 RAAEEAEEARVQA 2078


>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
          Length = 4533

 Score = 32.3 bits (72), Expect = 0.42
 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 24/106 (22%)

Query: 76   ASSEELARQRGVLERTEKMVDKMDQDLKISQKHINSIKSVFGGLVNYFK-----SKPVET 130
            A  E+L +++ +LE  E+  +K+++  + ++++IN+IK     LV Y       + P + 
Sbjct: 1229 AVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKK 1288

Query: 131  PPEQNG-------------------TLTSQPNNRLKEAISTSKEQE 157
            P  Q+G                   TLTSQ    + E +   +E+E
Sbjct: 1289 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEE 1334



 Score = 32.0 bits (71), Expect = 0.55
 Identities = 15/77 (19%), Positives = 42/77 (54%)

Query: 42   QQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKMDQD 101
            QQ +++EV+RR EA   +  +  ++  E +++  +S  E+  +    E  E+   +++++
Sbjct: 1380 QQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEE 1439

Query: 102  LKISQKHINSIKSVFGG 118
            +++ +  + + +   GG
Sbjct: 1440 IRVVRLQLEATERQRGG 1456



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 29/133 (21%), Positives = 59/133 (44%), Gaps = 10/133 (7%)

Query: 39   ADRQQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKM 98
            A RQ+ L  E  RR         +SLA   E+ +   A+ EE+ R +  +E   ++ ++ 
Sbjct: 1955 AARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERA 2014

Query: 99   DQD--------LKISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTSQPNNRLKEAI 150
            +Q+         + +QK + + +      V   K + ++   +Q  ++  Q     + A 
Sbjct: 2015 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ-KEQELQQTLQQEQSVLDQLRGEAEAAR 2073

Query: 151  STSKE-QEAKYQA 162
              ++E +EA+ QA
Sbjct: 2074 RAAEEAEEARVQA 2086


>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
          Length = 4574

 Score = 32.3 bits (72), Expect = 0.42
 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 24/106 (22%)

Query: 76   ASSEELARQRGVLERTEKMVDKMDQDLKISQKHINSIKSVFGGLVNYFK-----SKPVET 130
            A  E+L +++ +LE  E+  +K+++  + ++++IN+IK     LV Y       + P + 
Sbjct: 1270 AVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKK 1329

Query: 131  PPEQNG-------------------TLTSQPNNRLKEAISTSKEQE 157
            P  Q+G                   TLTSQ    + E +   +E+E
Sbjct: 1330 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEE 1375



 Score = 32.0 bits (71), Expect = 0.55
 Identities = 15/77 (19%), Positives = 42/77 (54%)

Query: 42   QQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKMDQD 101
            QQ +++EV+RR EA   +  +  ++  E +++  +S  E+  +    E  E+   +++++
Sbjct: 1421 QQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEE 1480

Query: 102  LKISQKHINSIKSVFGG 118
            +++ +  + + +   GG
Sbjct: 1481 IRVVRLQLEATERQRGG 1497



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 29/133 (21%), Positives = 59/133 (44%), Gaps = 10/133 (7%)

Query: 39   ADRQQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKM 98
            A RQ+ L  E  RR         +SLA   E+ +   A+ EE+ R +  +E   ++ ++ 
Sbjct: 1996 AARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERA 2055

Query: 99   DQD--------LKISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTSQPNNRLKEAI 150
            +Q+         + +QK + + +      V   K + ++   +Q  ++  Q     + A 
Sbjct: 2056 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ-KEQELQQTLQQEQSVLDQLRGEAEAAR 2114

Query: 151  STSKE-QEAKYQA 162
              ++E +EA+ QA
Sbjct: 2115 RAAEEAEEARVQA 2127


>gi|40538794 coiled-coil domain containing 21 [Homo sapiens]
          Length = 762

 Score = 32.3 bits (72), Expect = 0.42
 Identities = 51/244 (20%), Positives = 101/244 (41%), Gaps = 16/244 (6%)

Query: 21  RPAPWRDARDLPDGPDAPADRQQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSE- 79
           RPAP+ D   L          Q+  R+    RA+    + + S   +   +K+  +  E 
Sbjct: 372 RPAPFGDVCLLR--------LQELQRENTFLRAQFAQKTEALSREKIDLEKKLSASEVEV 423

Query: 80  ELARQ--RGVLERTEKMVDKMDQDLKISQKHINSIKSVF--GGLVNYFKSKPVETPPEQN 135
           +L R+  +  L++  + V K ++ +K   KHIN++K         N  K + +ET     
Sbjct: 424 QLIRESLKVALQKHSEEVKKQEERVKGRDKHINNLKKKCQKESEQNREKQQRIETLERYL 483

Query: 136 GTL-TSQPNNRLKEAISTSKEQEAKYQASHPNLRK-LDDTDPVPRGAGSAMSTDAYPKNP 193
             L T + + +  + +  S+ +  + Q     L   L++T  + R     + +    +  
Sbjct: 484 ADLPTLEDHQKQSQQLKDSELKSTELQEKVTELESLLEETQAICREKEIQLESLRQREAE 543

Query: 194 HLRAYHQKIDSNLDELSMGLGRLKDIALGMQTEIEEQDDILDRLTTKVDKLDVNIKSTER 253
              A H   D    E + G G   ++    Q   +    I+++   K+D+L   ++S E+
Sbjct: 544 FSSAGHSLQDKQSVEETSGEGPEVEME-SWQKRYDSLQKIVEKQQQKMDQLRSQVQSLEQ 602

Query: 254 KVRQ 257
           +V Q
Sbjct: 603 EVAQ 606


>gi|238908495 similar to pleckstrin homology domain protein (5V327)
           [Homo sapiens]
          Length = 506

 Score = 32.0 bits (71), Expect = 0.55
 Identities = 41/196 (20%), Positives = 82/196 (41%), Gaps = 18/196 (9%)

Query: 66  LMYESEKVGVASS--EELARQRGVLERTEKMVDKMDQDLKISQKHINSIKSVFGGLVNYF 123
           LM E+E++ +     EEL R   VLE  ++  +++ Q+L++ Q+ I     +    +   
Sbjct: 170 LMEETEELCLQREQREELERLNQVLEAEKQQFEEVVQELRMEQEQIKRELELTARCL--- 226

Query: 124 KSKPVETPPEQNGTLTSQPNNRLKEAISTSKEQEAKYQASHPNLRKLDDTDPVPRGAGSA 183
             K VE   ++   LT      L+E     K+     + +  +L+ L +    P  +G  
Sbjct: 227 --KGVEQEKKELRHLTESLQQTLEELSIEKKKTLEMLEENENHLQTLANQSEQPPPSGGL 284

Query: 184 MSTDAYPKNPHLRAYHQKIDSNLDELSMGLGRLK---DIALGMQTEIEEQDDILDRLTTK 240
            S        +LR   +K+   L+E  +   R+K   + +  ++ E E        L   
Sbjct: 285 HS--------NLRQIEEKMQQLLEEKLLAEKRMKENEERSRALEEEREFYSSQSQALQNS 336

Query: 241 VDKLDVNIKSTERKVR 256
           + +L    +  ER+++
Sbjct: 337 LQELTAEKQQAERELK 352


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 32.0 bits (71), Expect = 0.55
 Identities = 33/172 (19%), Positives = 72/172 (41%), Gaps = 19/172 (11%)

Query: 95   VDKMDQDLKISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTSQPNNRLKEAISTSK 154
            ++K+   ++     I  + + F   +    ++  E   E++ T++ +    LK     ++
Sbjct: 2282 IEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFE-ERSATISKEWEQDLKSLKEKNE 2340

Query: 155  EQEAKYQASHPNLRKLDDTDPVPRGAGSAMSTDAYPKNPHLRAYHQKIDSN-LDELSMGL 213
            +    YQ    +L      +P          T    KNPH+ +   ++ +  + EL   L
Sbjct: 2341 KLFKNYQTLKTSLASGAQVNP----------TTQDNKNPHVTSRATQLTTEKIRELENSL 2390

Query: 214  GRLKDIALG-------MQTEIEEQDDILDRLTTKVDKLDVNIKSTERKVRQL 258
               K+ A+        MQ E+E  +DI+ +L  KV + +  ++ T+  ++ L
Sbjct: 2391 HEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVL 2442


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score = 32.0 bits (71), Expect = 0.55
 Identities = 46/226 (20%), Positives = 87/226 (38%), Gaps = 32/226 (14%)

Query: 45   LRQEVLRRAEATAASTSRSLALMYES----EKVGVASSEELARQRGVLERTEKMVDKMDQ 100
            L Q  L+  +A      R  A ++E     E+     + EL   R  LE+ E+     +Q
Sbjct: 1694 LMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQ 1753

Query: 101  DLKISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTSQPNNRLKEAISTSKEQEAKY 160
            +L  + + +N + S   GL+N  K    +          +Q +  ++EA    +E E K 
Sbjct: 1754 ELLEATERLNLLHSQNTGLLNQKKKLEAD---------LAQLSGEVEEAAQERREAEEKA 1804

Query: 161  QASHPNLRKLDDTDPVPRGAGSAMSTDAYPKNPHLRAYHQKIDSNLDELSMGLGRLKDIA 220
            +      + + D   +         T A     HL    + ++  + EL   L   +  A
Sbjct: 1805 K------KAITDAAMMAEELKKEQDTSA-----HLERMKKTLEQTVRELQARLEEAEQAA 1853

Query: 221  L--------GMQTEIEEQDDILDRLTTKVDKLDVNIKSTERKVRQL 258
            L         ++ ++ E +  LD    K  +    ++  ER+V++L
Sbjct: 1854 LRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKEL 1899



 Score = 28.5 bits (62), Expect = 6.1
 Identities = 48/225 (21%), Positives = 86/225 (38%), Gaps = 20/225 (8%)

Query: 48   EVLRRAEATAASTSRSLALMYESEKVGVASSEELARQ-------RGVLERTEKMVDKMDQ 100
            E L RA+A+A    R+        K+ V   EEL RQ       RG L+     + ++ +
Sbjct: 1285 ETLTRAKASAEKLCRTYEDQLSEAKIKV---EELQRQLADASTQRGRLQTESGELSRLLE 1341

Query: 101  DLKISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTS-QPNNRLKEAISTSKEQEAK 159
            + +     ++  K++    +   + +  E    ++    + Q      + +    E+EA+
Sbjct: 1342 EKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAE 1401

Query: 160  YQASHPNLRKLDDTDPVPRGAGSAMSTDAYPKNPHLRAYHQKIDSNLDELSMGL------ 213
             QA    L  L   +       S    DA  +   L    +K+   L E   G+      
Sbjct: 1402 AQAELQRL--LSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAK 1459

Query: 214  -GRLKDIALGMQTEIEEQDDILDRLTTKVDKLDVNIKSTERKVRQ 257
               L+   L +QTE E+    L+R T+    LD   +  ER + +
Sbjct: 1460 CSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEE 1504


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 32.0 bits (71), Expect = 0.55
 Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 3/79 (3%)

Query: 180  AGSAMSTDAYPKNPHLRAYHQKIDSNLDELSMGLGRLKDIALGMQTEIEEQDDILDRLTT 239
            AG     +  PK   L+    K + ++  LS  L   +     +QTEI EQ+D++  L T
Sbjct: 1382 AGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHT 1441

Query: 240  KVDKLDVNIKSTERKVRQL 258
               +L++  K  + +++QL
Sbjct: 1442 ---QLEMQAKEHDERIKQL 1457



 Score = 29.3 bits (64), Expect = 3.6
 Identities = 40/215 (18%), Positives = 87/215 (40%), Gaps = 29/215 (13%)

Query: 46   RQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKMDQDLKIS 105
            +Q++ R+ +A   S   +L       K   +  EEL+  RG +ER  K +  ++  +   
Sbjct: 1478 KQQIQRKLQAALISRKEAL-------KENKSLQEELSLARGTIERLTKSLADVESQVSAQ 1530

Query: 106  QKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTSQPNNRLKEAISTSKEQEA---KYQA 162
             K  +++      L             E+   L ++ +  L E  S S   E+     + 
Sbjct: 1531 NKEKDTVLGRLALL------------QEERDKLITEMDRSLLENQSLSSSCESLKLALEG 1578

Query: 163  SHPNLRKLDDTDPVPRGAGSAMSTDAYPKNPHLRAYHQKIDSNLDELSMGLGRLKDIALG 222
               +  KL       + +  A ST+   K+  L+  ++ +  + + +S    R++ +   
Sbjct: 1579 LTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEA 1638

Query: 223  MQTEIEEQDDILDRLTTKVDKLDVNIKSTERKVRQ 257
            ++ E +E       L  K+   + N K TE+++++
Sbjct: 1639 VRQEKQE-------LYGKLRSTEANKKETEKQLQE 1666


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.128    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,702,348
Number of Sequences: 37866
Number of extensions: 432620
Number of successful extensions: 1842
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 1708
Number of HSP's gapped (non-prelim): 192
length of query: 258
length of database: 18,247,518
effective HSP length: 100
effective length of query: 158
effective length of database: 14,460,918
effective search space: 2284825044
effective search space used: 2284825044
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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