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Search of human proteins with 4758710
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758710 mesenchyme homeobox 1 isoform 1 [Homo sapiens]
(254 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758710 mesenchyme homeobox 1 isoform 1 [Homo sapiens] 532 e-151
gi|7710150 mesenchyme homeobox 1 isoform 2 [Homo sapiens] 334 4e-92
gi|91208415 mesenchyme homeobox 1 isoform 3 [Homo sapiens] 283 1e-76
gi|84105335 mesenchyme homeobox 2 [Homo sapiens] 185 4e-47
gi|149588930 gastrulation brain homeo box 1 [Homo sapiens] 90 2e-18
gi|194363768 homeobox D9 [Homo sapiens] 88 8e-18
gi|24497517 homeobox A5 [Homo sapiens] 85 5e-17
gi|24497533 homeobox C10 [Homo sapiens] 85 7e-17
gi|23097236 homeobox A9 [Homo sapiens] 84 9e-17
gi|45593144 gastrulation brain homeo box 2 [Homo sapiens] 84 9e-17
gi|15029508 homeobox B9 [Homo sapiens] 84 1e-16
gi|24497513 homeobox A3 isoform a [Homo sapiens] 84 2e-16
gi|13562112 homeobox A3 isoform a [Homo sapiens] 84 2e-16
gi|24497538 homeobox C4 [Homo sapiens] 84 2e-16
gi|24497540 homeobox C4 [Homo sapiens] 84 2e-16
gi|24497515 homeobox A3 isoform b [Homo sapiens] 83 3e-16
gi|84570137 homeobox B3 [Homo sapiens] 82 3e-16
gi|5031759 homeobox A11 [Homo sapiens] 82 5e-16
gi|4504465 homeobox B2 [Homo sapiens] 81 8e-16
gi|89257348 homeo box HB9 [Homo sapiens] 81 1e-15
gi|13273315 homeobox B4 [Homo sapiens] 81 1e-15
gi|148613882 homeobox A4 [Homo sapiens] 80 1e-15
gi|23397672 homeobox D4 [Homo sapiens] 80 2e-15
gi|85068580 homeobox B7 [Homo sapiens] 80 2e-15
gi|4885127 caudal type homeobox 4 [Homo sapiens] 80 2e-15
gi|19923391 homeobox D3 [Homo sapiens] 79 3e-15
gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens] 79 3e-15
gi|5031761 homeobox A1 isoform a [Homo sapiens] 79 3e-15
gi|14149760 orthopedia homeobox [Homo sapiens] 79 3e-15
gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens] 78 6e-15
>gi|4758710 mesenchyme homeobox 1 isoform 1 [Homo sapiens]
Length = 254
Score = 532 bits (1371), Expect = e-151
Identities = 254/254 (100%), Positives = 254/254 (100%)
Query: 1 MDPAASSCMRSLQPPAPVWGCLRNPHSEGNGASGLPHYPPTPFSFHQKPDFLATATAAYP 60
MDPAASSCMRSLQPPAPVWGCLRNPHSEGNGASGLPHYPPTPFSFHQKPDFLATATAAYP
Sbjct: 1 MDPAASSCMRSLQPPAPVWGCLRNPHSEGNGASGLPHYPPTPFSFHQKPDFLATATAAYP 60
Query: 61 DFSASCLAATPHSLPQEEHIFTEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSS 120
DFSASCLAATPHSLPQEEHIFTEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSS
Sbjct: 61 DFSASCLAATPHSLPQEEHIFTEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSS 120
Query: 121 LGLVDTTGGPGDDYGVLGSTANETEKKSSRRRKESSDNQENRGKPEGSSKARKERTAFTK 180
LGLVDTTGGPGDDYGVLGSTANETEKKSSRRRKESSDNQENRGKPEGSSKARKERTAFTK
Sbjct: 121 LGLVDTTGGPGDDYGVLGSTANETEKKSSRRRKESSDNQENRGKPEGSSKARKERTAFTK 180
Query: 181 EQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPISPNGQ 240
EQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPISPNGQ
Sbjct: 181 EQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPISPNGQ 240
Query: 241 DPEDGDSTASPSSE 254
DPEDGDSTASPSSE
Sbjct: 241 DPEDGDSTASPSSE 254
>gi|7710150 mesenchyme homeobox 1 isoform 2 [Homo sapiens]
Length = 184
Score = 334 bits (857), Expect = 4e-92
Identities = 161/177 (90%), Positives = 166/177 (93%), Gaps = 1/177 (0%)
Query: 1 MDPAASSCMRSLQPPAPVWGCLRNPHSEGNGASGLPHYPPTPFSFHQKPDFLATATAAYP 60
MDPAASSCMRSLQPPAPVWGCLRNPHSEGNGASGLPHYPPTPFSFHQKPDFLATATAAYP
Sbjct: 1 MDPAASSCMRSLQPPAPVWGCLRNPHSEGNGASGLPHYPPTPFSFHQKPDFLATATAAYP 60
Query: 61 DFSASCLAATPHSLPQEEHIFTEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSS 120
DFSASCLAATPHSLPQEEHIFTEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSS
Sbjct: 61 DFSASCLAATPHSLPQEEHIFTEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSS 120
Query: 121 LGLVDTTGGPGDDYGVLGSTANETEKKSSRRRKESSDNQENRGKPEGSSKARKERTA 177
LGLVDTTGGPGDDYGVLGSTANETEKKSSRRRKESS Q +P+ +A + R+A
Sbjct: 121 LGLVDTTGGPGDDYGVLGSTANETEKKSSRRRKESS-GQSVVPEPKDEVEACEGRSA 176
>gi|91208415 mesenchyme homeobox 1 isoform 3 [Homo sapiens]
Length = 139
Score = 283 bits (723), Expect = 1e-76
Identities = 139/139 (100%), Positives = 139/139 (100%)
Query: 116 MGTSSLGLVDTTGGPGDDYGVLGSTANETEKKSSRRRKESSDNQENRGKPEGSSKARKER 175
MGTSSLGLVDTTGGPGDDYGVLGSTANETEKKSSRRRKESSDNQENRGKPEGSSKARKER
Sbjct: 1 MGTSSLGLVDTTGGPGDDYGVLGSTANETEKKSSRRRKESSDNQENRGKPEGSSKARKER 60
Query: 176 TAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPI 235
TAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPI
Sbjct: 61 TAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPI 120
Query: 236 SPNGQDPEDGDSTASPSSE 254
SPNGQDPEDGDSTASPSSE
Sbjct: 121 SPNGQDPEDGDSTASPSSE 139
>gi|84105335 mesenchyme homeobox 2 [Homo sapiens]
Length = 304
Score = 185 bits (469), Expect = 4e-47
Identities = 120/255 (47%), Positives = 144/255 (56%), Gaps = 47/255 (18%)
Query: 17 PVWGCLRNPHSEGNGASGLPHYPPTPFSFHQKPDFLATATAAYPDFSASCLAATPHSLPQ 76
P++GCLR+PH+ A GL + + + H + D ++ YP+ S S + P
Sbjct: 4 PLFGCLRSPHAT---AQGLHPFSQSSLALHGRSDHMS-----YPELSTSSSSCIIAGYPN 55
Query: 77 EEHIFTEQHPAFPQ-------------------SPNWHFPV-----SDARRRPNSGP-AG 111
EE +F QH NWH P S AR P +G
Sbjct: 56 EEGMFASQHHRGHHHHHHHHHHHHHQQQQHQALQTNWHLPQMSSPPSAARHSLCLQPDSG 115
Query: 112 GSKEMGTS---------SLGLVDTTGG---PGDDYGVLGSTANETEKKSSRRRK-ESSDN 158
G E+G+S SLG TG PGD YG + E EK+S +RK +SSD+
Sbjct: 116 GPPELGSSPPVLCSNSSSLGSSTPTGAACAPGD-YGRQALSPAEAEKRSGGKRKSDSSDS 174
Query: 159 QENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVW 218
QE K E +SK RKERTAFTKEQ+RELEAEFAHHNYLTRLRRYEIAVNLDL+ERQVKVW
Sbjct: 175 QEGNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVW 234
Query: 219 FQNRRMKWKRVKGGQ 233
FQNRRMKWKRVKGGQ
Sbjct: 235 FQNRRMKWKRVKGGQ 249
>gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]
Length = 363
Score = 90.1 bits (222), Expect = 2e-18
Identities = 80/270 (29%), Positives = 107/270 (39%), Gaps = 53/270 (19%)
Query: 12 LQPPAPVWGCLRNPHSEGNG---------ASGLPHYPPTPFSFHQKPDFLATATAAYPDF 62
L P A G L N G G + LP + P +F+ + A A AA
Sbjct: 73 LAPLASFAGRLTNTFCAGLGQAVPSMVALTTALPSFAEPPDAFYGPQELAAAAAAA---- 128
Query: 63 SASCLAATPHS--------------LPQEEHI----------FTEQHPAFPQSPNWHFPV 98
+A+ P LP E + F+E P+ P +
Sbjct: 129 AATAARNNPEPGGRRPEGGLEADELLPAREKVAEPPPPPPPHFSETFPSLPAEGKVYSSD 188
Query: 99 SDARRRPNSGPAGGSKEMGTSSLGLVDTTGGPGDDYGVLGSTAN--------ETEKKSSR 150
+ PAG +E + +GG +D G L S+A + + K S
Sbjct: 189 EEKLEASAGDPAGSEQEE--------EGSGGDSEDDGFLDSSAGGPGALLGPKPKLKGSL 240
Query: 151 RRKESSDNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDL 210
G K+R+ RTAFT EQL ELE EF YL+ R +IA L L
Sbjct: 241 GTGAEEGAPVTAGVTAPGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKL 300
Query: 211 SERQVKVWFQNRRMKWKRVKGGQPISPNGQ 240
SE QVK+WFQNRR KWKR+K G S +G+
Sbjct: 301 SEVQVKIWFQNRRAKWKRIKAGNVSSRSGE 330
>gi|194363768 homeobox D9 [Homo sapiens]
Length = 352
Score = 87.8 bits (216), Expect = 8e-18
Identities = 69/210 (32%), Positives = 98/210 (46%), Gaps = 17/210 (8%)
Query: 29 GNGASGLPHYPPTPFSFHQKPDFLAT---ATAAYPDFSASCLAATPHSLPQEEHIFTEQH 85
G G S P P + KP+ A ATAA S+S ++ + Q
Sbjct: 142 GRGPSPGPSGPANGRHYGIKPETRAAPAPATAASTTSSSSTSLSSSSKRTECSVARESQG 201
Query: 86 PAFPQ-SPNWHFPVSDARRRPNSGPAGGSKEMGTSSLGLVDTTGGPGD-----DYGVLGS 139
+ P+ S N A +GP G +G TGG + D+ + G
Sbjct: 202 SSGPEFSCNSFLQEKAAAATGGTGPGAG--------IGAATGTGGSSEPSACSDHPIPGC 253
Query: 140 TANETEKKSSRRRKESSDNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRL 199
+ E EK+ S+ +++ D + RK+R +TK Q ELE EF + YLTR
Sbjct: 254 SLKEEEKQHSQPQQQQLDPNNPAANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRD 313
Query: 200 RRYEIAVNLDLSERQVKVWFQNRRMKWKRV 229
RRYE+A L+L+ERQVK+WFQNRRMK K++
Sbjct: 314 RRYEVARILNLTERQVKIWFQNRRMKMKKM 343
>gi|24497517 homeobox A5 [Homo sapiens]
Length = 270
Score = 85.1 bits (209), Expect = 5e-17
Identities = 69/210 (32%), Positives = 100/210 (47%), Gaps = 26/210 (12%)
Query: 31 GASGLPHYPPTPFSFHQKPDFLATATAAYPDFSASCLAATPHSLPQEEHIFTEQHPAFPQ 90
G SG H+ S + + A+A+AA + S A + HS PQ + + P
Sbjct: 57 GRSGSGHFG----SGERARSYAASASAAPAEPRYSQPATSTHS-PQPDPLPCSAVAPSPG 111
Query: 91 SPNWHFPVSDARRRPNSGPAGGSKEMGTSSLGL---VDTTGGPGDDYGVLGSTANETEKK 147
S + H + S +G S + G++ + V T G +D A+ +
Sbjct: 112 SDSHH-----GGKNSLSNSSGASADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEP 166
Query: 148 SSRR---------RKESSDNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTR 198
S ++ + +N G PEG ++ RTA+T+ Q ELE EF + YLTR
Sbjct: 167 SPAPPAQPQIYPWMRKLHISHDNIGGPEG----KRARTAYTRYQTLELEKEFHFNRYLTR 222
Query: 199 LRRYEIAVNLDLSERQVKVWFQNRRMKWKR 228
RR EIA L LSERQ+K+WFQNRRMKWK+
Sbjct: 223 RRRIEIAHALCLSERQIKIWFQNRRMKWKK 252
>gi|24497533 homeobox C10 [Homo sapiens]
Length = 342
Score = 84.7 bits (208), Expect = 7e-17
Identities = 57/193 (29%), Positives = 80/193 (41%), Gaps = 7/193 (3%)
Query: 37 HYPPTPFSFHQKPDFLATATAAYPDFSASCLAATPHSLPQEEHIFTEQHPAFPQSPNWHF 96
H P P + P + A D + C A P E+ +SP
Sbjct: 141 HEVPVPSYYRASPSYSAL------DKTPHCSGANDFEAPFEQRASLNPRAEHLESPQLGG 194
Query: 97 PVSDARRRPNSGPAGGSKEMGTSSLGLVDTTGGPGDDYGVLGSTANETEKKSSRRRKESS 156
VS + E+ T L G P + A+ + S KE
Sbjct: 195 KVSFPETPKSDSQTPSPNEIKTEQ-SLAGPKGSPSESEKERAKAADSSPDTSDNEAKEEI 253
Query: 157 DNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVK 216
+ G + RK+R +TK Q ELE EF + YLTR RR EI+ ++L++RQVK
Sbjct: 254 KAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVK 313
Query: 217 VWFQNRRMKWKRV 229
+WFQNRRMK K++
Sbjct: 314 IWFQNRRMKLKKM 326
>gi|23097236 homeobox A9 [Homo sapiens]
Length = 272
Score = 84.3 bits (207), Expect = 9e-17
Identities = 78/246 (31%), Positives = 105/246 (42%), Gaps = 49/246 (19%)
Query: 3 PAASSCMRSLQPPAPVWGCLRNPHSEGNGASGLP-----HYPPTPFSFHQKPDFLATATA 57
P S C S Q A V+G NP GA+ +P H+ P+ Q P A
Sbjct: 49 PDFSPC--SFQSKATVFGASWNP-VHAAGANAVPAAVYHHHHHHPYVHPQAP-----VAA 100
Query: 58 AYPD--FSASCLAATPHSLPQEEHIFTEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSKE 115
A PD + S L TP +L P S + + P S G
Sbjct: 101 AAPDGRYMRSWLEPTPGAL---------SFAGLPSSRPYGI-----KPEPLSARRGDCPT 146
Query: 116 MGTSSLGLVD-TTGGPGDDYGVLGSTANETEKKSSRRRKESSDNQENRGKPE-------- 166
+ T +L L D G P D E + + +++N+ KP
Sbjct: 147 LDTHTLSLTDYACGSPPVD--------REKQPSEGAFSENNAENESGGDKPPIDPNNPAA 198
Query: 167 ---GSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRR 223
+ RK+R +TK Q ELE EF + YLTR RRYE+A L+L+ERQVK+WFQNRR
Sbjct: 199 NWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRR 258
Query: 224 MKWKRV 229
MK K++
Sbjct: 259 MKMKKI 264
>gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]
Length = 348
Score = 84.3 bits (207), Expect = 9e-17
Identities = 48/108 (44%), Positives = 61/108 (56%), Gaps = 1/108 (0%)
Query: 133 DYGVLGSTANETEKKSSRRRKESSDNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAH 192
D + G A++ E+ +E+ + G + K R+ RTAFT EQL ELE EF
Sbjct: 210 DDNLTGQAAHK-EEDPGHALEETPPSSGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHC 268
Query: 193 HNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPISPNGQ 240
YL+ R +IA L LSE QVK+WFQNRR KWKRVK G S G+
Sbjct: 269 KKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAGNANSKTGE 316
>gi|15029508 homeobox B9 [Homo sapiens]
Length = 250
Score = 84.0 bits (206), Expect = 1e-16
Identities = 66/195 (33%), Positives = 92/195 (47%), Gaps = 25/195 (12%)
Query: 60 PDFSASCLAATPH---SLPQEEHIFTEQHPAFPQSPN----WHFPVSDARRRPNSGPAGG 112
P F AS +PH SLP H + + P W P P G A
Sbjct: 57 PVFGASWAPLSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAV 116
Query: 113 SKEMGTSSLGLVDTTGGPGDDYGVLGSTANETEKKSSRRRKESSDNQ-----ENRGKPEG 167
E + G + G P +Y + T+ E S +R DN+ E++ +P+
Sbjct: 117 KAEPLLGAPGELLKQGTP--EYSL--ETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQ 172
Query: 168 SS---------KARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVW 218
++ +RK+R +TK Q ELE EF + YLTR RR+E+A L+LSERQVK+W
Sbjct: 173 TNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIW 232
Query: 219 FQNRRMKWKRVKGGQ 233
FQNRRMK K++ Q
Sbjct: 233 FQNRRMKMKKMNKEQ 247
>gi|24497513 homeobox A3 isoform a [Homo sapiens]
Length = 443
Score = 83.6 bits (205), Expect = 2e-16
Identities = 53/161 (32%), Positives = 82/161 (50%), Gaps = 16/161 (9%)
Query: 86 PAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSSLGLVDTTGGPGDDYGVLGSTANETE 145
PA P P+ P +A P A S + + ++ + E+
Sbjct: 116 PAAPPPPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQ------------IFPWMKESR 163
Query: 146 KKSSRRRKESSDNQENRG--KPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYE 203
+ + ++ SS + G P G + +++ RTA+T QL ELE EF + YL R RR E
Sbjct: 164 QNTKQKTSSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVE 223
Query: 204 IAVNLDLSERQVKVWFQNRRMKWKRVKGGQPI--SPNGQDP 242
+A L+L+ERQ+K+WFQNRRMK+K+ + G+ + S GQ P
Sbjct: 224 MANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSP 264
>gi|13562112 homeobox A3 isoform a [Homo sapiens]
Length = 443
Score = 83.6 bits (205), Expect = 2e-16
Identities = 53/161 (32%), Positives = 82/161 (50%), Gaps = 16/161 (9%)
Query: 86 PAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSSLGLVDTTGGPGDDYGVLGSTANETE 145
PA P P+ P +A P A S + + ++ + E+
Sbjct: 116 PAAPPPPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQ------------IFPWMKESR 163
Query: 146 KKSSRRRKESSDNQENRG--KPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYE 203
+ + ++ SS + G P G + +++ RTA+T QL ELE EF + YL R RR E
Sbjct: 164 QNTKQKTSSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVE 223
Query: 204 IAVNLDLSERQVKVWFQNRRMKWKRVKGGQPI--SPNGQDP 242
+A L+L+ERQ+K+WFQNRRMK+K+ + G+ + S GQ P
Sbjct: 224 MANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSP 264
>gi|24497538 homeobox C4 [Homo sapiens]
Length = 264
Score = 83.6 bits (205), Expect = 2e-16
Identities = 67/208 (32%), Positives = 93/208 (44%), Gaps = 49/208 (23%)
Query: 33 SGLPH-----YPPTPFSFHQKPDFLATATAAYPDFSASCLA------ATPHSLPQEEHIF 81
SG H YPP P +YP+ SC + + H Q H
Sbjct: 43 SGFQHHHQELYPPPP------------PRPSYPERQYSCTSLQGPGNSRGHGPAQAGH-- 88
Query: 82 TEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSSLGLVDTTGGPGDDYGVLGSTA 141
HP QS P+S A P+ P S+ P D+ ++
Sbjct: 89 --HHPEKSQSLCEPAPLSGASASPSPAPPACSQ---------------PAPDHPSSAASK 131
Query: 142 NETEKKSSRRRKESSDNQE-NRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLR 200
++ S+ N N G+P ++ RTA+T++Q+ ELE EF ++ YLTR R
Sbjct: 132 QPIVYPWMKKIHVSTVNPNYNGGEP------KRSRTAYTRQQVLELEKEFHYNRYLTRRR 185
Query: 201 RYEIAVNLDLSERQVKVWFQNRRMKWKR 228
R EIA +L LSERQ+K+WFQNRRMKWK+
Sbjct: 186 RIEIAHSLCLSERQIKIWFQNRRMKWKK 213
>gi|24497540 homeobox C4 [Homo sapiens]
Length = 264
Score = 83.6 bits (205), Expect = 2e-16
Identities = 67/208 (32%), Positives = 93/208 (44%), Gaps = 49/208 (23%)
Query: 33 SGLPH-----YPPTPFSFHQKPDFLATATAAYPDFSASCLA------ATPHSLPQEEHIF 81
SG H YPP P +YP+ SC + + H Q H
Sbjct: 43 SGFQHHHQELYPPPP------------PRPSYPERQYSCTSLQGPGNSRGHGPAQAGH-- 88
Query: 82 TEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSSLGLVDTTGGPGDDYGVLGSTA 141
HP QS P+S A P+ P S+ P D+ ++
Sbjct: 89 --HHPEKSQSLCEPAPLSGASASPSPAPPACSQ---------------PAPDHPSSAASK 131
Query: 142 NETEKKSSRRRKESSDNQE-NRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLR 200
++ S+ N N G+P ++ RTA+T++Q+ ELE EF ++ YLTR R
Sbjct: 132 QPIVYPWMKKIHVSTVNPNYNGGEP------KRSRTAYTRQQVLELEKEFHYNRYLTRRR 185
Query: 201 RYEIAVNLDLSERQVKVWFQNRRMKWKR 228
R EIA +L LSERQ+K+WFQNRRMKWK+
Sbjct: 186 RIEIAHSLCLSERQIKIWFQNRRMKWKK 213
>gi|24497515 homeobox A3 isoform b [Homo sapiens]
Length = 285
Score = 82.8 bits (203), Expect = 3e-16
Identities = 44/104 (42%), Positives = 66/104 (63%), Gaps = 4/104 (3%)
Query: 143 ETEKKSSRRRKESSDNQENRG--KPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLR 200
E+ + + ++ SS + G P G + +++ RTA+T QL ELE EF + YL R R
Sbjct: 3 ESRQNTKQKTSSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPR 62
Query: 201 RYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPI--SPNGQDP 242
R E+A L+L+ERQ+K+WFQNRRMK+K+ + G+ + S GQ P
Sbjct: 63 RVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSP 106
>gi|84570137 homeobox B3 [Homo sapiens]
Length = 431
Score = 82.4 bits (202), Expect = 3e-16
Identities = 48/93 (51%), Positives = 61/93 (65%), Gaps = 9/93 (9%)
Query: 165 PEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRM 224
P GS+ +++ RTA+T QL ELE EF + YL R RR E+A L+LSERQ+K+WFQNRRM
Sbjct: 182 PPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRM 241
Query: 225 KWK---RVKG-----GQPISPNGQDPEDGDSTA 249
K+K + KG G P SP G P+ STA
Sbjct: 242 KYKKDQKAKGLASSSGGP-SPAGSPPQPMQSTA 273
>gi|5031759 homeobox A11 [Homo sapiens]
Length = 313
Score = 82.0 bits (201), Expect = 5e-16
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 13/136 (9%)
Query: 107 SGPAGGSKEMGTSSLGLVDTTGGPGDDYGVLGS------TANETEKKSSRRRKESSDNQE 160
S G TS+ TG P G TA E+K RRR ESS + E
Sbjct: 164 SAEKGPPAATATSAAAAAAATGAPATSSSDSGGGGGCRETAAAAEEKERRRRPESSSSPE 223
Query: 161 NRG-----KPEGSS--KARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSER 213
+ K GSS + RK+R +TK Q+RELE EF Y+ + +R +++ L+L++R
Sbjct: 224 SSSGHTEDKAGGSSGQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDR 283
Query: 214 QVKVWFQNRRMKWKRV 229
QVK+WFQNRRMK K++
Sbjct: 284 QVKIWFQNRRMKEKKI 299
>gi|4504465 homeobox B2 [Homo sapiens]
Length = 356
Score = 81.3 bits (199), Expect = 8e-16
Identities = 52/119 (43%), Positives = 66/119 (55%), Gaps = 24/119 (20%)
Query: 145 EKKSSRRRKESSDNQ----------------ENRGKPE-GSSKARKERTAFTKEQLRELE 187
EKKS+++ +S+ + + G PE G AR+ RTA+T QL ELE
Sbjct: 100 EKKSAKKPSQSATSPSPAASAVPASGVGSPADGLGLPEAGGGGARRLRTAYTNTQLLELE 159
Query: 188 AEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPISPNGQDPEDGD 246
EF + YL R RR EIA LDL+ERQVKVWFQNRRMK KR ++P DG+
Sbjct: 160 KEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR-------QTQHREPPDGE 211
>gi|89257348 homeo box HB9 [Homo sapiens]
Length = 401
Score = 80.9 bits (198), Expect = 1e-15
Identities = 37/61 (60%), Positives = 48/61 (78%)
Query: 170 KARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRV 229
K R+ RTAFT +QL ELE +F + YL+R +R+E+A +L L+E QVK+WFQNRRMKWKR
Sbjct: 240 KCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRS 299
Query: 230 K 230
K
Sbjct: 300 K 300
>gi|13273315 homeobox B4 [Homo sapiens]
Length = 251
Score = 80.9 bits (198), Expect = 1e-15
Identities = 42/84 (50%), Positives = 53/84 (63%), Gaps = 16/84 (19%)
Query: 172 RKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKR--- 228
++ RTA+T++Q+ ELE EF ++ YLTR RR EIA L LSERQ+K+WFQNRRMKWK+
Sbjct: 163 KRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKKDHK 222
Query: 229 -------------VKGGQPISPNG 239
GG P PNG
Sbjct: 223 LPNTKIRSGGAAGSAGGPPGRPNG 246
>gi|148613882 homeobox A4 [Homo sapiens]
Length = 320
Score = 80.5 bits (197), Expect = 1e-15
Identities = 40/68 (58%), Positives = 50/68 (73%), Gaps = 6/68 (8%)
Query: 161 NRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQ 220
N G+P ++ RTA+T++Q+ ELE EF + YLTR RR EIA L LSERQVK+WFQ
Sbjct: 211 NGGEP------KRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQ 264
Query: 221 NRRMKWKR 228
NRRMKWK+
Sbjct: 265 NRRMKWKK 272
>gi|23397672 homeobox D4 [Homo sapiens]
Length = 255
Score = 79.7 bits (195), Expect = 2e-15
Identities = 36/57 (63%), Positives = 46/57 (80%)
Query: 172 RKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKR 228
++ RTA+T++Q+ ELE EF + YLTR RR EIA L LSERQ+K+WFQNRRMKWK+
Sbjct: 155 KRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKK 211
>gi|85068580 homeobox B7 [Homo sapiens]
Length = 217
Score = 79.7 bits (195), Expect = 2e-15
Identities = 62/208 (29%), Positives = 86/208 (41%), Gaps = 33/208 (15%)
Query: 55 ATAAYPDFSASCLAATPHSLPQEEHIFTEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSK 114
AT A+P+ ++ A+ P Q P + F S P G G
Sbjct: 22 ATGAFPEQTSCAFASNP------------QRPGYGAGSGASFAASMQGLYPGGGGMAGQS 69
Query: 115 EMGTSSLG--------------LVDTTGG--PGDDYGVLGSTANETEKKSSRRRKESSDN 158
G + G G PGD A E++ S ES+
Sbjct: 70 AAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDS----AKAAGAKEQRDSDLAAESNFR 125
Query: 159 QENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVW 218
+ G+ + R +T +T+ Q ELE EF ++ YLTR RR EIA L L+ERQ+K+W
Sbjct: 126 IYPWMRSSGTDRKRGRQT-YTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIW 184
Query: 219 FQNRRMKWKRVKGGQPISPNGQDPEDGD 246
FQNRRMKWK+ GQD + +
Sbjct: 185 FQNRRMKWKKENKTAGPGTTGQDRAEAE 212
>gi|4885127 caudal type homeobox 4 [Homo sapiens]
Length = 284
Score = 79.7 bits (195), Expect = 2e-15
Identities = 78/237 (32%), Positives = 104/237 (43%), Gaps = 35/237 (14%)
Query: 29 GNGASGLP--HYPPTP-FSFHQKPDFLATATAAYPDFSASCLAATPHSLPQEEHIFTEQH 85
G G S +P ++ P FS + + + +P + +P+S P+E+ +
Sbjct: 33 GGGGSPMPASNFAAAPAFSHYMGYPHMPSMDPHWPSLG---VWGSPYSPPREDW---SVY 86
Query: 86 PAFPQSPNWHFPVSDARRRP---------NSGPAGGSKEMGTSSLGLVDTTGGPGDDYGV 136
P P S PV+D P N GP GG GTS L PG G
Sbjct: 87 PG-PSSTMGTVPVNDVTSSPAAFCSTDYSNLGPVGG----GTSGSSL------PGQAGGS 135
Query: 137 LGSTANETEKKSSRRRKESSDNQENRGKPEGSSKAR---KERTAFTKEQLRELEAEFAHH 193
L T K SS R S R + + K R K R +T Q ELE EF +
Sbjct: 136 LVPTDAGAAKASSPSRSRHSPYAWMRKTVQVTGKTRTKEKYRVVYTDHQRLELEKEFHCN 195
Query: 194 NYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRV---KGGQPISPNGQDPEDGDS 247
Y+T R+ E+AVNL LSERQVK+WFQNRR K +++ K Q + G D DS
Sbjct: 196 RYITIQRKSELAVNLGLSERQVKIWFQNRRAKERKMIKKKISQFENSGGSVQSDSDS 252
>gi|19923391 homeobox D3 [Homo sapiens]
Length = 432
Score = 79.3 bits (194), Expect = 3e-15
Identities = 61/164 (37%), Positives = 80/164 (48%), Gaps = 9/164 (5%)
Query: 82 TEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSSLGLVDTTGGPGDDYGVLGSTA 141
+EQ P P P P S PA K G + T + S
Sbjct: 112 SEQQPPQPPPPPPTLPPSSPTNPGGGVPA--KKPKGGPNASSSSATISKQIFPWMKESRQ 169
Query: 142 NETEKKSSRRRKESSDNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRR 201
N +K S ES E++ P +SK + RTA+T QL ELE EF + YL R RR
Sbjct: 170 NSKQKNSCATAGESC---EDKSPPGPASK--RVRTAYTSAQLVELEKEFHFNRYLCRPRR 224
Query: 202 YEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPI--SPNGQDPE 243
E+A L+L+ERQ+K+WFQNRRMK+K+ + + I SP Q PE
Sbjct: 225 VEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPE 268
>gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]
Length = 325
Score = 79.3 bits (194), Expect = 3e-15
Identities = 45/128 (35%), Positives = 66/128 (51%), Gaps = 4/128 (3%)
Query: 107 SGPAGGSKEMGTSSLGLVDTTGGPGDDYGVLGST----ANETEKKSSRRRKESSDNQENR 162
S P G ++ +S + T PG+D +GST A + + + N
Sbjct: 36 SDPGGHPGDLAPNSDPVEGATLLPGEDITTVGSTPASLAVSAKDPDKQPGPQGGPNPSQA 95
Query: 163 GKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNR 222
G+ +G K ++ RT FT QL ELE FA +Y R E+A+ + L+E +V+VWFQNR
Sbjct: 96 GQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNR 155
Query: 223 RMKWKRVK 230
R KWK+ K
Sbjct: 156 RAKWKKRK 163
>gi|5031761 homeobox A1 isoform a [Homo sapiens]
Length = 335
Score = 79.3 bits (194), Expect = 3e-15
Identities = 46/82 (56%), Positives = 53/82 (64%), Gaps = 4/82 (4%)
Query: 175 RTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKR--VKGG 232
RT FT +QL ELE EF + YLTR RR EIA +L L+E QVK+WFQNRRMK K+ +G
Sbjct: 233 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL 292
Query: 233 QPISPNGQDPEDGDSTASPSSE 254
PISP P D A SSE
Sbjct: 293 LPISP--ATPPGNDEKAEESSE 312
>gi|14149760 orthopedia homeobox [Homo sapiens]
Length = 325
Score = 79.3 bits (194), Expect = 3e-15
Identities = 45/128 (35%), Positives = 66/128 (51%), Gaps = 4/128 (3%)
Query: 107 SGPAGGSKEMGTSSLGLVDTTGGPGDDYGVLGST----ANETEKKSSRRRKESSDNQENR 162
S P G ++ +S + T PG+D +GST A + + + N
Sbjct: 36 SDPGGHPGDLAPNSDPVEGATLLPGEDITTVGSTPASLAVSAKDPDKQPGPQGGPNPSQA 95
Query: 163 GKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNR 222
G+ +G K ++ RT FT QL ELE FA +Y R E+A+ + L+E +V+VWFQNR
Sbjct: 96 GQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNR 155
Query: 223 RMKWKRVK 230
R KWK+ K
Sbjct: 156 RAKWKKRK 163
>gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]
Length = 283
Score = 78.2 bits (191), Expect = 6e-15
Identities = 38/88 (43%), Positives = 55/88 (62%), Gaps = 5/88 (5%)
Query: 172 RKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVK- 230
++ RTA+T+ QL ELE EF + Y++R RR E+AV L+L+ER +K+WFQNRRMKWK+ +
Sbjct: 147 KRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEED 206
Query: 231 ----GGQPISPNGQDPEDGDSTASPSSE 254
GG + G + D + E
Sbjct: 207 KKRGGGTAVGGGGVAEPEQDCAVTSGEE 234
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,559,241
Number of Sequences: 37866
Number of extensions: 661012
Number of successful extensions: 3457
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 302
Number of HSP's successfully gapped in prelim test: 139
Number of HSP's that attempted gapping in prelim test: 2863
Number of HSP's gapped (non-prelim): 679
length of query: 254
length of database: 18,247,518
effective HSP length: 100
effective length of query: 154
effective length of database: 14,460,918
effective search space: 2226981372
effective search space used: 2226981372
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.