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Search of human proteins with 4758502
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758502 hyaluronan binding protein 2 preproprotein [Homo
sapiens]
(560 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758502 hyaluronan binding protein 2 preproprotein [Homo sapi... 1219 0.0
gi|4504383 HGF activator preproprotein [Homo sapiens] 307 2e-83
gi|4505861 plasminogen activator, tissue isoform 1 preproprotein... 278 1e-74
gi|14702169 plasminogen activator, tissue isoform 3 preproprotei... 278 1e-74
gi|145275213 coagulation factor XII precursor [Homo sapiens] 249 4e-66
gi|222537759 plasminogen activator, urokinase isoform 2 [Homo sa... 246 3e-65
gi|4505863 plasminogen activator, urokinase isoform 1 preproprot... 246 3e-65
gi|4505881 plasminogen [Homo sapiens] 211 1e-54
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens] 191 1e-48
gi|4506143 neurotrypsin precursor [Homo sapiens] 162 8e-40
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 159 8e-39
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 159 8e-39
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 157 2e-38
gi|4503649 coagulation factor IX preproprotein [Homo sapiens] 155 9e-38
gi|118498341 chymotrypsin B1 [Homo sapiens] 152 1e-36
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 150 4e-36
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] 149 9e-36
gi|148613878 acrosin precursor [Homo sapiens] 148 1e-35
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 148 1e-35
gi|4506153 prostasin preproprotein [Homo sapiens] 147 3e-35
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 147 3e-35
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 146 4e-35
gi|118498350 chymotrypsin B2 [Homo sapiens] 146 4e-35
gi|4758508 transmembrane protease, serine 11D [Homo sapiens] 146 4e-35
gi|68508970 tryptase beta 2 precursor [Homo sapiens] 145 1e-34
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa... 144 2e-34
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap... 144 2e-34
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 142 1e-33
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 141 2e-33
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 141 2e-33
>gi|4758502 hyaluronan binding protein 2 preproprotein [Homo
sapiens]
Length = 560
Score = 1219 bits (3154), Expect = 0.0
Identities = 560/560 (100%), Positives = 560/560 (100%)
Query: 1 MFARMSDLHVLLLMALVGKTACGFSLMSLLESLDPDWTPDQYDYSYEDYNQEENTSSTLT 60
MFARMSDLHVLLLMALVGKTACGFSLMSLLESLDPDWTPDQYDYSYEDYNQEENTSSTLT
Sbjct: 1 MFARMSDLHVLLLMALVGKTACGFSLMSLLESLDPDWTPDQYDYSYEDYNQEENTSSTLT 60
Query: 61 HAENPDWYYTEDQADPCQPNPCEHGGDCLVHGSTFTCSCLAPFSGNKCQKVQNTCKDNPC 120
HAENPDWYYTEDQADPCQPNPCEHGGDCLVHGSTFTCSCLAPFSGNKCQKVQNTCKDNPC
Sbjct: 61 HAENPDWYYTEDQADPCQPNPCEHGGDCLVHGSTFTCSCLAPFSGNKCQKVQNTCKDNPC 120
Query: 121 GRGQCLITQSPPYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGATCSRHKRRSKFTCACPD 180
GRGQCLITQSPPYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGATCSRHKRRSKFTCACPD
Sbjct: 121 GRGQCLITQSPPYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGATCSRHKRRSKFTCACPD 180
Query: 181 QFKGKFCEIGSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGI 240
QFKGKFCEIGSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGI
Sbjct: 181 QFKGKFCEIGSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGI 240
Query: 241 GEHNFCRNPDADEKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDS 300
GEHNFCRNPDADEKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDS
Sbjct: 241 GEHNFCRNPDADEKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDS 300
Query: 301 CGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTA 360
CGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTA
Sbjct: 301 CGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTA 360
Query: 361 AHCTDIKTRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPV 420
AHCTDIKTRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPV
Sbjct: 361 AHCTDIKTRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPV 420
Query: 421 DGHCALESKYVKTVCLPDGSFPSGSECHISGWGVTETGKGSRQLLDAKVKLIANTLCNSR 480
DGHCALESKYVKTVCLPDGSFPSGSECHISGWGVTETGKGSRQLLDAKVKLIANTLCNSR
Sbjct: 421 DGHCALESKYVKTVCLPDGSFPSGSECHISGWGVTETGKGSRQLLDAKVKLIANTLCNSR 480
Query: 481 QLYDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECGKRPGVY 540
QLYDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECGKRPGVY
Sbjct: 481 QLYDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECGKRPGVY 540
Query: 541 TQVTKFLNWIKATIKSESGF 560
TQVTKFLNWIKATIKSESGF
Sbjct: 541 TQVTKFLNWIKATIKSESGF 560
>gi|4504383 HGF activator preproprotein [Homo sapiens]
Length = 655
Score = 307 bits (786), Expect = 2e-83
Identities = 178/498 (35%), Positives = 260/498 (52%), Gaps = 30/498 (6%)
Query: 75 DPCQPNPCEHGGDC--LVHGSTFTCSCLAPFSGNKC---QKVQNTCKDNPCGRGQCLITQ 129
DPC PC +GG C ++ CSC F+G C + T + G + +
Sbjct: 162 DPCASGPCLNGGSCSNTQDPQSYHCSCPRAFTGKDCGTEKCFDETRYEYLEGGDRWARVR 221
Query: 130 SPPYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEI 189
+C C T ++ C +PC NG TC CACP F G+ C I
Sbjct: 222 QGHVEQCECFGGRTWCEGTRHT-ACLSSPCLNGGTCHLIVATGTTVCACPPGFAGRLCNI 280
Query: 190 GSDD-CYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRN 248
D+ C++G+G YRG + + + +CL WNS LL QE + + A G+G H +CRN
Sbjct: 281 EPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRN 340
Query: 249 PDADEKPWCFIKVTNDKVKWEYCDVSACSA--QDVAYPEESPTEPSTKLPGFDSCGKTEI 306
PD DE+PWC++ V + + WEYC + AC + + P+ T P PG +CG+
Sbjct: 341 PDNDERPWCYV-VKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQACGRRHK 399
Query: 307 AERKIK-RIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCTD 365
++ RI GG S G HPW A++ FC G+L+H CWV++AAHC
Sbjct: 400 KRTFLRPRIIGGSSSLPGSHPWLAAIYIG---------DSFCAGSLVHTCWVVSAAHCFS 450
Query: 366 IKTRH--LKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGH 423
+ VVLG + Q+F +EK Y+ Y+ + H D+ L++LK
Sbjct: 451 HSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDH-DLVLIRLKKKGDR 509
Query: 424 CALESKYVKTVCLPD--GSFPSGSECHISGWG-VTETGKG-SRQLLDAKVKLIANTLCNS 479
CA S++V+ +CLP+ +FP+G +C I+GWG + E G S L +A V L+A+ C+S
Sbjct: 510 CATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSS 569
Query: 480 RQLYDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECGK--RP 537
++Y I +M+CAG D CQGDSGGPL CEK+G Y+YGI+SWG CG+ +P
Sbjct: 570 PEVYGADISPNMLCAGYFDCK-SDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKP 628
Query: 538 GVYTQVTKFLNWIKATIK 555
GVYT+V +++WI I+
Sbjct: 629 GVYTRVANYVDWINDRIR 646
Score = 44.7 bits (104), Expect = 2e-04
Identities = 37/133 (27%), Positives = 51/133 (38%), Gaps = 24/133 (18%)
Query: 70 TEDQADPCQPNPCEHGGDCLVHGSTFTCSCLAPFSGNKCQKVQNTCKDNPCGRGQCLITQ 129
TED PC+ P +GG L C+ C N +D G C+
Sbjct: 102 TED-GRPCR-FPFRYGGRML-----HACTSEGSAHRKWCATTHNYDRDRAWG--YCVEAT 152
Query: 130 SPPYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEI 189
PP GP+ + C PC NG +CS + + C+CP F GK C
Sbjct: 153 PPP----------GGPAA---LDPCASGPCLNGGSCSNTQDPQSYHCSCPRAFTGKDC-- 197
Query: 190 GSDDCYVGDGYSY 202
G++ C+ Y Y
Sbjct: 198 GTEKCFDETRYEY 210
>gi|4505861 plasminogen activator, tissue isoform 1 preproprotein
[Homo sapiens]
Length = 562
Score = 278 bits (710), Expect = 1e-74
Identities = 178/513 (34%), Positives = 257/513 (50%), Gaps = 71/513 (13%)
Query: 77 CQPNPCEHGGDC--LVHGSTFTCSCLAPFSGNKCQ-KVQNTCKDNP--CGRGQCLITQSP 131
C C +GG C ++ S F C C F+G C+ + TC ++ RG +S
Sbjct: 86 CSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGTWSTAESG 145
Query: 132 PYYR-----CVCKHPYTGPSCSQVVPVCRPNPCQNGAT----CSRHKRRSKFTCAC--PD 180
+ + PY+G RP+ + G C R SK C
Sbjct: 146 AECTNWNSSALAQKPYSGR---------RPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAG 196
Query: 181 QFKGKFCEI-----GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDA 235
++ +FC G+ DCY G+G +YRG + T + +CL WNS +L+ + Y A
Sbjct: 197 KYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSA 256
Query: 236 ETHGIGEHNFCRNPDADEKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKL 295
+ G+G+HN+CRNPD D KPWC + + N ++ WEYCDV +CS
Sbjct: 257 QALGLGKHNYCRNPDGDAKPWCHV-LKNRRLTWEYCDVPSCS------------------ 297
Query: 296 PGFDSCGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPC 355
+CG + ++ + RI GG + HPWQA++ + S + CGG LI C
Sbjct: 298 ----TCGLRQYSQPQF-RIKGGLFADIASHPWQAAIFAK--HRRSPGERFLCGGILISSC 350
Query: 356 WVLTAAHCTD--IKTRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIA 413
W+L+AAHC HL V+LG EQ F VEK + ++ D+ NDIA
Sbjct: 351 WILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFD--DDTYDNDIA 408
Query: 414 LLKLKPVDGHCALESKYVKTVCLP--DGSFPSGSECHISGWGVTETGKG--SRQLLDAKV 469
LL+LK CA ES V+TVCLP D P +EC +SG+G E S +L +A V
Sbjct: 409 LLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHV 468
Query: 470 KLIANTLCNSRQLYDHMIDDSMICAGNLQKPG-----QDTCQGDSGGPLTCEKDGTYYVY 524
+L ++ C S+ L + + D+M+CAG+ + G D CQGDSGGPL C DG +
Sbjct: 469 RLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLV 528
Query: 525 GIVSWGLECGKR--PGVYTQVTKFLNWIKATIK 555
GI+SWGL CG++ PGVYT+VT +L+WI+ ++
Sbjct: 529 GIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMR 561
Score = 108 bits (271), Expect = 1e-23
Identities = 59/145 (40%), Positives = 73/145 (50%), Gaps = 7/145 (4%)
Query: 136 CVCKHPYTGPSCSQVVPV--CRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEIGS-D 192
C C +G + VPV C C NG TC + S F C CP+ F GK CEI +
Sbjct: 69 CWCN---SGRAQCHSVPVKSCSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCEIDTRA 125
Query: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252
CY G SYRG + + C WNS L Q+ Y+ DA G+G HN+CRNPD D
Sbjct: 126 TCYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRD 185
Query: 253 EKPWCFIKVTNDKVKWEYCDVSACS 277
KPWC++ K E+C ACS
Sbjct: 186 SKPWCYV-FKAGKYSSEFCSTPACS 209
>gi|14702169 plasminogen activator, tissue isoform 3 preproprotein
[Homo sapiens]
Length = 516
Score = 278 bits (710), Expect = 1e-74
Identities = 178/513 (34%), Positives = 257/513 (50%), Gaps = 71/513 (13%)
Query: 77 CQPNPCEHGGDC--LVHGSTFTCSCLAPFSGNKCQ-KVQNTCKDNP--CGRGQCLITQSP 131
C C +GG C ++ S F C C F+G C+ + TC ++ RG +S
Sbjct: 40 CSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGTWSTAESG 99
Query: 132 PYYR-----CVCKHPYTGPSCSQVVPVCRPNPCQNGAT----CSRHKRRSKFTCAC--PD 180
+ + PY+G RP+ + G C R SK C
Sbjct: 100 AECTNWNSSALAQKPYSGR---------RPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAG 150
Query: 181 QFKGKFCEI-----GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDA 235
++ +FC G+ DCY G+G +YRG + T + +CL WNS +L+ + Y A
Sbjct: 151 KYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSA 210
Query: 236 ETHGIGEHNFCRNPDADEKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKL 295
+ G+G+HN+CRNPD D KPWC + + N ++ WEYCDV +CS
Sbjct: 211 QALGLGKHNYCRNPDGDAKPWCHV-LKNRRLTWEYCDVPSCS------------------ 251
Query: 296 PGFDSCGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPC 355
+CG + ++ + RI GG + HPWQA++ + S + CGG LI C
Sbjct: 252 ----TCGLRQYSQPQF-RIKGGLFADIASHPWQAAIFAK--HRRSPGERFLCGGILISSC 304
Query: 356 WVLTAAHCTD--IKTRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIA 413
W+L+AAHC HL V+LG EQ F VEK + ++ D+ NDIA
Sbjct: 305 WILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFD--DDTYDNDIA 362
Query: 414 LLKLKPVDGHCALESKYVKTVCLP--DGSFPSGSECHISGWGVTETGKG--SRQLLDAKV 469
LL+LK CA ES V+TVCLP D P +EC +SG+G E S +L +A V
Sbjct: 363 LLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHV 422
Query: 470 KLIANTLCNSRQLYDHMIDDSMICAGNLQKPG-----QDTCQGDSGGPLTCEKDGTYYVY 524
+L ++ C S+ L + + D+M+CAG+ + G D CQGDSGGPL C DG +
Sbjct: 423 RLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLV 482
Query: 525 GIVSWGLECGKR--PGVYTQVTKFLNWIKATIK 555
GI+SWGL CG++ PGVYT+VT +L+WI+ ++
Sbjct: 483 GIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMR 515
>gi|145275213 coagulation factor XII precursor [Homo sapiens]
Length = 615
Score = 249 bits (637), Expect = 4e-66
Identities = 182/542 (33%), Positives = 251/542 (46%), Gaps = 103/542 (19%)
Query: 80 NPCEHGGDCLVHGSTFTCSCLAPFSGNKCQKVQNTCKDNPCGRGQCLI----------TQ 129
+PC+ GG C+ S C C +GN CQK + C Q L T+
Sbjct: 102 SPCQKGGTCVNMPSGPHCLCPQHLTGNHCQKEK-------CFEPQLLRFFHKNEIWYRTE 154
Query: 130 SPPYYRCVCKHPYTGPSCSQVVP-VCRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCE 188
RC CK P C ++ CR NPC +G C + C CP + G FC+
Sbjct: 155 QAAVARCQCKGP--DAHCQRLASQACRTNPCLHGGRCLEVEGHR--LCHCPVGYTGAFCD 210
Query: 189 IGSD-DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCR 247
+ + CY G G SYRG T++ C W S + N+ E A G+G H FCR
Sbjct: 211 VDTKASCYDGRGLSYRGLARTTLSGAPCQPWASEATYR---NVTAEQARNWGLGGHAFCR 267
Query: 248 NPDADEKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEE--SPT---------------E 290
NPD D +PWCF+ + D++ WEYCD++ C A P SP +
Sbjct: 268 NPDNDIRPWCFV-LNRDRLSWEYCDLAQCQTPTQAAPPTPVSPRLHVPLMPAQPAPPKPQ 326
Query: 291 PSTKLP----------------------GFDSCG-KTEIAERKIKRIYGGFKSTAGKHPW 327
P+T+ P G SCG + + + R+ GG + G HP+
Sbjct: 327 PTTRTPPQSQTPGALPAKREQPPSLTRNGPLSCGQRLRKSLSSMTRVVGGLVALRGAHPY 386
Query: 328 QASLQSSLPLTISMPQGH-FCGGALIHPCWVLTAAHCTDIK--TRHLKVVLGDQDLKK-- 382
A+L GH FC G+LI PCWVLTAAHC + L VVLG +
Sbjct: 387 IAALY----------WGHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQERRNHSC 436
Query: 383 ---EEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKL-KPVDGHCALESKYVKTVCLPD 438
+ +S+R+ + F Y +D+ALL+L + DG CAL S YV+ VCLP
Sbjct: 437 EPCQTLAVRSYRLHEAFSPVSY-------QHDLALLRLQEDADGSCALLSPYVQPVCLPS 489
Query: 439 GSF-PSGSE-CHISGWGVTETG--KGSRQLLDAKVKLIANTLCNSRQLYDHMIDDSMICA 494
G+ PS + C ++GWG G + + L +A+V ++ C++ ++ I M+CA
Sbjct: 490 GAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCA 549
Query: 495 GNLQKPGQDTCQGDSGGPLTCEKDGT---YYVYGIVSWGLECGKR--PGVYTQVTKFLNW 549
G L+ G D CQGDSGGPL CE + GI+SWG CG R PGVYT V +L W
Sbjct: 550 GFLE-GGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLAW 608
Query: 550 IK 551
I+
Sbjct: 609 IR 610
Score = 37.0 bits (84), Expect = 0.048
Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 4/84 (4%)
Query: 41 QYDYSYEDYNQEENTSSTLTHAENPDWYYTEDQADPCQPNPCEHGGDCLVHGSTFTCSCL 100
++ + E + + E + + PD + + C+ NPC HGG CL C C
Sbjct: 142 RFFHKNEIWYRTEQAAVARCQCKGPDAHCQRLASQACRTNPCLHGGRCLEVEGHRLCHCP 201
Query: 101 APFSGNKCQ-KVQNTCKDNPCGRG 123
++G C + +C D GRG
Sbjct: 202 VGYTGAFCDVDTKASCYD---GRG 222
>gi|222537759 plasminogen activator, urokinase isoform 2 [Homo
sapiens]
Length = 414
Score = 246 bits (629), Expect = 3e-65
Identities = 153/413 (37%), Positives = 210/413 (50%), Gaps = 29/413 (7%)
Query: 159 CQNGATCSRHKRRSKFT-CACPDQFKGKFCEIG-SDDCYVGDGYSYRGKMNRTVNQHACL 216
C NG TC +K S C CP +F G+ CEI S CY G+G+ YRGK + CL
Sbjct: 16 CLNGGTCVSNKYFSNIHWCNCPKKFGGQHCEIDKSKTCYEGNGHFYRGKASTDTMGRPCL 75
Query: 217 YWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDADEKPWCFIKVTNDKVKWEYCDVSAC 276
WNS +LQ+ Y+ DA G+G+HN+CRNPD +PWC+++V + V C
Sbjct: 76 PWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRRRPWCYVQVGLKPL------VQEC 129
Query: 277 SAQDVAYPEESPTEPSTKLPGFDSCGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLP 336
D A + P+ P +L CG+ + R +I GG +T PW A++
Sbjct: 130 MVHDCA-DGKKPSSPPEELK--FQCGQKTLRPR--FKIIGGEFTTIENQPWFAAIYRR-- 182
Query: 337 LTISMPQGHFCGGALIHPCWVLTAAHC--TDIKTRHLKVVLGDQDLKKEEFHEQSFRVEK 394
+ CGG+LI PCWV++A HC K V LG L E F VE
Sbjct: 183 -HRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVEN 241
Query: 395 IFKYSHYNERDEIPHNDIALLKLKPVDGHCALESKYVKTVCLP----DGSFPSGSECHIS 450
+ + Y+ HNDIALLK++ +G CA S+ ++T+CLP D F G+ C I+
Sbjct: 242 LILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQF--GTSCEIT 299
Query: 451 GWGVTETGK--GSRQLLDAKVKLIANTLCNSRQLYDHMIDDSMICAGNLQKPGQDTCQGD 508
G+G + QL VKLI++ C Y + M+CA + Q D+CQGD
Sbjct: 300 GFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWK-TDSCQGD 358
Query: 509 SGGPLTCEKDGTYYVYGIVSWGLECG--KRPGVYTQVTKFLNWIKATIKSESG 559
SGGPL C G + GIVSWG C +PGVYT+V+ FL WI++ K E+G
Sbjct: 359 SGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKEENG 411
>gi|4505863 plasminogen activator, urokinase isoform 1 preproprotein
[Homo sapiens]
Length = 431
Score = 246 bits (629), Expect = 3e-65
Identities = 153/413 (37%), Positives = 210/413 (50%), Gaps = 29/413 (7%)
Query: 159 CQNGATCSRHKRRSKFT-CACPDQFKGKFCEIG-SDDCYVGDGYSYRGKMNRTVNQHACL 216
C NG TC +K S C CP +F G+ CEI S CY G+G+ YRGK + CL
Sbjct: 33 CLNGGTCVSNKYFSNIHWCNCPKKFGGQHCEIDKSKTCYEGNGHFYRGKASTDTMGRPCL 92
Query: 217 YWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDADEKPWCFIKVTNDKVKWEYCDVSAC 276
WNS +LQ+ Y+ DA G+G+HN+CRNPD +PWC+++V + V C
Sbjct: 93 PWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRRRPWCYVQVGLKPL------VQEC 146
Query: 277 SAQDVAYPEESPTEPSTKLPGFDSCGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLP 336
D A + P+ P +L CG+ + R +I GG +T PW A++
Sbjct: 147 MVHDCA-DGKKPSSPPEELK--FQCGQKTLRPR--FKIIGGEFTTIENQPWFAAIYRR-- 199
Query: 337 LTISMPQGHFCGGALIHPCWVLTAAHC--TDIKTRHLKVVLGDQDLKKEEFHEQSFRVEK 394
+ CGG+LI PCWV++A HC K V LG L E F VE
Sbjct: 200 -HRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVEN 258
Query: 395 IFKYSHYNERDEIPHNDIALLKLKPVDGHCALESKYVKTVCLP----DGSFPSGSECHIS 450
+ + Y+ HNDIALLK++ +G CA S+ ++T+CLP D F G+ C I+
Sbjct: 259 LILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQF--GTSCEIT 316
Query: 451 GWGVTETGK--GSRQLLDAKVKLIANTLCNSRQLYDHMIDDSMICAGNLQKPGQDTCQGD 508
G+G + QL VKLI++ C Y + M+CA + Q D+CQGD
Sbjct: 317 GFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWK-TDSCQGD 375
Query: 509 SGGPLTCEKDGTYYVYGIVSWGLECG--KRPGVYTQVTKFLNWIKATIKSESG 559
SGGPL C G + GIVSWG C +PGVYT+V+ FL WI++ K E+G
Sbjct: 376 SGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKEENG 428
>gi|4505881 plasminogen [Homo sapiens]
Length = 810
Score = 211 bits (537), Expect = 1e-54
Identities = 131/373 (35%), Positives = 189/373 (50%), Gaps = 50/373 (13%)
Query: 192 DDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDA 251
+DC G+G YRGK TV C W + +++F + E N+CRNPD
Sbjct: 479 EDCMFGNGKGYRGKRATTVTGTPCQDWAAQE--PHRHSIFTPETNPRAGLEKNYCRNPDG 536
Query: 252 DEK-PWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDSCGKTEIAERK 310
D PWC+ TN + ++YCDV C+A P FD CGK ++ +K
Sbjct: 537 DVGGPWCY--TTNPRKLYDYCDVPQCAA-----------------PSFD-CGKPQVEPKK 576
Query: 311 IK-RIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCTDIKTR 369
R+ GG + PWQ SL++ + HFCGG LI P WVLTAAHC + R
Sbjct: 577 CPGRVVGGCVAHPHSWPWQVSLRTRFGM-------HFCGGTLISPEWVLTAAHCLEKSPR 629
Query: 370 --HLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGHCALE 427
KV+LG E H Q V ++F E DIALLKL A+
Sbjct: 630 PSSYKVILGAHQEVNLEPHVQEIEVSRLFL--------EPTRKDIALLKLSSP----AVI 677
Query: 428 SKYVKTVCLPDGSF--PSGSECHISGWGVTETGKGSRQLLDAKVKLIANTLCNSRQLYDH 485
+ V CLP ++ +EC I+GWG T+ G+ L +A++ +I N +CN + +
Sbjct: 678 TDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNG 737
Query: 486 MIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECGK--RPGVYTQV 543
+ + +CAG+L G D+CQGDSGGPL C + Y + G+ SWGL C + +PGVY +V
Sbjct: 738 RVQSTELCAGHLAG-GTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRV 796
Query: 544 TKFLNWIKATIKS 556
++F+ WI+ +++
Sbjct: 797 SRFVTWIEGVMRN 809
Score = 79.3 bits (194), Expect = 8e-15
Identities = 40/111 (36%), Positives = 56/111 (50%), Gaps = 7/111 (6%)
Query: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252
DCY GDG SYRG + T C W+S + + E+ G+ N+CRNPDAD
Sbjct: 376 DCYHGDGQSYRGTSSTTTTGKKCQSWSS--MTPHRHQKTPENYPNAGL-TMNYCRNPDAD 432
Query: 253 EKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTE--PSTKLPGFDSC 301
+ PWCF T+ V+WEYC++ CS + + P P + P + C
Sbjct: 433 KGPWCF--TTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDC 481
Score = 78.6 bits (192), Expect = 1e-14
Identities = 37/108 (34%), Positives = 55/108 (50%), Gaps = 5/108 (4%)
Query: 194 CYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDADE 253
C G G +YRG + TV+ H C +W++ +N E+ + E N+CRNPD
Sbjct: 275 CLKGTGENYRGNVAVTVSGHTCQHWSAQT--PHTHNRTPENFPCKNLDE-NYCRNPDGKR 331
Query: 254 KPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDSC 301
PWC TN +V+WEYC + +C + V+ + +PT P P C
Sbjct: 332 APWCH--TTNSQVRWEYCKIPSCDSSPVSTEQLAPTAPPELTPVVQDC 377
Score = 60.8 bits (146), Expect = 3e-09
Identities = 30/88 (34%), Positives = 51/88 (57%), Gaps = 6/88 (6%)
Query: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252
+C G+G +YRG M++T N C W+S + ++ +E G+ E N+CRNPD D
Sbjct: 102 ECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSE--GL-EENYCRNPDND 158
Query: 253 -EKPWCFIKVTNDKVKWEYCDVSACSAQ 279
+ PWC+ T+ + +++YCD+ C +
Sbjct: 159 PQGPWCY--TTDPEKRYDYCDILECEEE 184
Score = 58.5 bits (140), Expect = 2e-08
Identities = 33/123 (26%), Positives = 59/123 (47%), Gaps = 10/123 (8%)
Query: 186 FCEI--GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEH 243
+C+I ++C G +Y GK+++T++ C W+S + + ++ + +
Sbjct: 175 YCDILECEEECMHCSGENYDGKISKTMSGLECQAWDSQ---SPHAHGYIPSKFPNKNLKK 231
Query: 244 NFCRNPDADEKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDSCGK 303
N+CRNPD + +PWCF T+ +WE CD+ C+ P PT K G + G
Sbjct: 232 NYCRNPDRELRPWCF--TTDPNKRWELCDIPRCTTPP---PSSGPTYQCLKGTGENYRGN 286
Query: 304 TEI 306
+
Sbjct: 287 VAV 289
>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
Length = 2040
Score = 191 bits (486), Expect = 1e-48
Identities = 142/432 (32%), Positives = 203/432 (46%), Gaps = 70/432 (16%)
Query: 138 CKHPY--TGPSCSQVVPVCRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEIG---SD 192
C++P TGP C + P R C N CS ++ T P + +G
Sbjct: 1665 CRNPDADTGPWCFTMDPSIRWEYC-NLTRCSD----TEGTVVAPPTVI-QVPSLGPPSEQ 1718
Query: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252
DC G+G YRGK TV C W + ++ F+ E N+CRNPD D
Sbjct: 1719 DCMFGNGKGYRGKKATTVTGTPCQEWAAQE--PHRHSTFIPGTNKWAGLEKNYCRNPDGD 1776
Query: 253 -EKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDSCGKTEIAERKI 311
PWC+ N + ++YCD+ C++ FD CGK ++ +K
Sbjct: 1777 INGPWCY--TMNPRKLFDYCDIPLCASSS-----------------FD-CGKPQVEPKKC 1816
Query: 312 K-RIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCTDIKTR- 369
I GG + PWQ SL++ HFCGG LI P WVLTAAHC +R
Sbjct: 1817 PGSIVGGCVAHPHSWPWQVSLRTRFGK-------HFCGGTLISPEWVLTAAHCLKKSSRP 1869
Query: 370 -HLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGHCALES 428
KV+LG E H Q V ++F E DIALLKL A+ +
Sbjct: 1870 SSYKVILGAHQEVNLESHVQEIEVSRLFL--------EPTQADIALLKLS----RPAVIT 1917
Query: 429 KYVKTVCLPDGSF--PSGSECHISGWGVTETGKGSRQLLDAKVKLIANTLCNSRQLYDHM 486
V CLP + + +EC+I+GWG T+ G+ L +A++ +I N +CN +
Sbjct: 1918 DKVMPACLPSPDYMVTARTECYITGWGETQGTFGTGLLKEAQLLVIENEVCNHYKY---- 1973
Query: 487 IDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECGK--RPGVYTQVT 544
ICA +L + G D+CQGDSGGPL C + Y + G+ SWGL C + +PGVY +V+
Sbjct: 1974 -----ICAEHLAR-GTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVS 2027
Query: 545 KFLNWIKATIKS 556
+F+ WI+ +++
Sbjct: 2028 RFVTWIEGMMRN 2039
Score = 79.7 bits (195), Expect = 6e-15
Identities = 41/110 (37%), Positives = 58/110 (52%), Gaps = 12/110 (10%)
Query: 190 GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249
G DCY GDG SYRG + TV C W+S + +++ + +G N+CRNP
Sbjct: 1164 GVQDCYHGDGQSYRGSFSTTVTGRTCQSWSS---MTPHWHQRTTEYYPNGGLTRNYCRNP 1220
Query: 250 DADEKPWCFIKVTNDKVKWEYCDVSACS-------AQDVAYPEESPTEPS 292
DA+ PWC+ N V+WEYC+++ C A A E++PTE S
Sbjct: 1221 DAEISPWCYTMDPN--VRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQS 1268
Score = 77.4 bits (189), Expect = 3e-14
Identities = 39/107 (36%), Positives = 59/107 (55%), Gaps = 9/107 (8%)
Query: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252
DCY GDG SYRG + TV C W+S + +++ + +G N+CRNPDA+
Sbjct: 1273 DCYHGDGQSYRGSFSTTVTGRTCQSWSS---MTPHWHQRTTEYYPNGGLTRNYCRNPDAE 1329
Query: 253 EKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPEESPTEPSTKLP 296
+PWC+ + V+WEYC+++ C + + P P PST+LP
Sbjct: 1330 IRPWCY--TMDPSVRWEYCNLTQCPVMESTLLTTPTVVPV-PSTELP 1373
Score = 76.6 bits (187), Expect = 5e-14
Identities = 39/113 (34%), Positives = 58/113 (51%), Gaps = 5/113 (4%)
Query: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252
DCY GDG SYRG + TV C W+S ++ + E+ G+ E N+CRNPD+
Sbjct: 1501 DCYHGDGRSYRGISSTTVTGRTCQSWSS--MIPHWHQRTPENYPNAGLTE-NYCRNPDSG 1557
Query: 253 EKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDSCGKTE 305
++PWC+ T+ V+WEYC+++ CS + E P + TE
Sbjct: 1558 KQPWCY--TTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTE 1608
Score = 73.6 bits (179), Expect = 5e-13
Identities = 44/121 (36%), Positives = 64/121 (52%), Gaps = 17/121 (14%)
Query: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252
DCY GDG SYRG + TV C W+S + +N E+ G+ N+CRNPDA
Sbjct: 27 DCYHGDGQSYRGTYSTTVTGRTCQAWSS--MTPHQHNRTTENYPNAGL-IMNYCRNPDAV 83
Query: 253 EKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPE-------ESPTE--PSTKLPGFDS 300
P+C+ + + V+WEYC+++ CS + VA P E+P+E P+ + PG
Sbjct: 84 AAPYCYTR--DPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQE 141
Query: 301 C 301
C
Sbjct: 142 C 142
Score = 73.6 bits (179), Expect = 5e-13
Identities = 37/110 (33%), Positives = 60/110 (54%), Gaps = 9/110 (8%)
Query: 190 GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249
G DCY GDG SYRG ++ T+ C W+S + +++ + + N+CRNP
Sbjct: 1384 GVQDCYRGDGQSYRGTLSTTITGRTCQSWSS---MTPHWHRRIPLYYPNAGLTRNYCRNP 1440
Query: 250 DADEKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPEESPTEPSTKLP 296
DA+ +PWC+ + V+WEYC+++ C + + P +P PST+ P
Sbjct: 1441 DAEIRPWCY--TMDPSVRWEYCNLTRCPVTESSVLTTPTVAPV-PSTEAP 1487
Score = 72.4 bits (176), Expect = 1e-12
Identities = 42/127 (33%), Positives = 60/127 (47%), Gaps = 23/127 (18%)
Query: 190 GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249
G DCY G SYRG + TV C W+S + ++ E+ G+ N+CRNP
Sbjct: 1050 GVQDCYYHYGQSYRGTYSTTVTGRTCQAWSS--MTPHQHSRTPENYPNAGL-TRNYCRNP 1106
Query: 250 DADEKPWCFIKVTNDKVKWEYCDVSACSAQD---------------VAYPEESPTEPSTK 294
DA+ +PWC+ + V+WEYC+++ C + A EE+PTE S
Sbjct: 1107 DAEIRPWCY--TMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQS-- 1162
Query: 295 LPGFDSC 301
PG C
Sbjct: 1163 -PGVQDC 1168
Score = 72.4 bits (176), Expect = 1e-12
Identities = 39/110 (35%), Positives = 54/110 (49%), Gaps = 7/110 (6%)
Query: 194 CYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDADE 253
CY G+G SYRG + TV C W+S + + E+ G+ N+CRNPDAD
Sbjct: 1616 CYHGNGQSYRGTFSTTVTGRTCQSWSS--MTPHRHQRTPENYPNDGL-TMNYCRNPDADT 1672
Query: 254 KPWCFIKVTNDKVKWEYCDVSACSAQD--VAYPEESPTEPSTKLPGFDSC 301
PWCF + ++WEYC+++ CS + V P PS P C
Sbjct: 1673 GPWCF--TMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDC 1720
Score = 68.2 bits (165), Expect = 2e-11
Identities = 42/124 (33%), Positives = 65/124 (52%), Gaps = 17/124 (13%)
Query: 190 GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249
G +CY G+G SYRG + TV C W+S + +++ E G+ N+CRNP
Sbjct: 138 GVQECYHGNGQSYRGTYSTTVTGRTCQAWSS--MTPHSHSRTPEYYPNAGL-IMNYCRNP 194
Query: 250 DADEKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPE-------ESPTE--PSTKLPG 297
DA P+C+ + + V+WEYC+++ CS + VA P E+P+E P+ + PG
Sbjct: 195 DAVAAPYCYTR--DPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 252
Query: 298 FDSC 301
C
Sbjct: 253 VQEC 256
Score = 68.2 bits (165), Expect = 2e-11
Identities = 42/124 (33%), Positives = 65/124 (52%), Gaps = 17/124 (13%)
Query: 190 GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249
G +CY G+G SYRG + TV C W+S + +++ E G+ N+CRNP
Sbjct: 252 GVQECYHGNGQSYRGTYSTTVTGRTCQAWSS--MTPHSHSRTPEYYPNAGL-IMNYCRNP 308
Query: 250 DADEKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPE-------ESPTE--PSTKLPG 297
DA P+C+ + + V+WEYC+++ CS + VA P E+P+E P+ + PG
Sbjct: 309 DAVAAPYCYTR--DPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 366
Query: 298 FDSC 301
C
Sbjct: 367 VQEC 370
Score = 68.2 bits (165), Expect = 2e-11
Identities = 42/124 (33%), Positives = 65/124 (52%), Gaps = 17/124 (13%)
Query: 190 GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249
G +CY G+G SYRG + TV C W+S + +++ E G+ N+CRNP
Sbjct: 366 GVQECYHGNGQSYRGTYSTTVTGRTCQAWSS--MTPHSHSRTPEYYPNAGL-IMNYCRNP 422
Query: 250 DADEKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPE-------ESPTE--PSTKLPG 297
DA P+C+ + + V+WEYC+++ CS + VA P E+P+E P+ + PG
Sbjct: 423 DAVAAPYCYTR--DPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 480
Query: 298 FDSC 301
C
Sbjct: 481 VQEC 484
Score = 68.2 bits (165), Expect = 2e-11
Identities = 42/124 (33%), Positives = 65/124 (52%), Gaps = 17/124 (13%)
Query: 190 GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249
G +CY G+G SYRG + TV C W+S + +++ E G+ N+CRNP
Sbjct: 480 GVQECYHGNGQSYRGTYSTTVTGRTCQAWSS--MTPHSHSRTPEYYPNAGL-IMNYCRNP 536
Query: 250 DADEKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPE-------ESPTE--PSTKLPG 297
DA P+C+ + + V+WEYC+++ CS + VA P E+P+E P+ + PG
Sbjct: 537 DAVAAPYCYTR--DPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 594
Query: 298 FDSC 301
C
Sbjct: 595 VQEC 598
Score = 68.2 bits (165), Expect = 2e-11
Identities = 42/124 (33%), Positives = 65/124 (52%), Gaps = 17/124 (13%)
Query: 190 GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249
G +CY G+G SYRG + TV C W+S + +++ E G+ N+CRNP
Sbjct: 594 GVQECYHGNGQSYRGTYSTTVTGRTCQAWSS--MTPHSHSRTPEYYPNAGL-IMNYCRNP 650
Query: 250 DADEKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPE-------ESPTE--PSTKLPG 297
DA P+C+ + + V+WEYC+++ CS + VA P E+P+E P+ + PG
Sbjct: 651 DAVAAPYCYTR--DPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 708
Query: 298 FDSC 301
C
Sbjct: 709 VQEC 712
Score = 68.2 bits (165), Expect = 2e-11
Identities = 42/124 (33%), Positives = 65/124 (52%), Gaps = 17/124 (13%)
Query: 190 GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249
G +CY G+G SYRG + TV C W+S + +++ E G+ N+CRNP
Sbjct: 708 GVQECYHGNGQSYRGTYSTTVTGRTCQAWSS--MTPHSHSRTPEYYPNAGL-IMNYCRNP 764
Query: 250 DADEKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPE-------ESPTE--PSTKLPG 297
DA P+C+ + + V+WEYC+++ CS + VA P E+P+E P+ + PG
Sbjct: 765 DAVAAPYCYTR--DPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 822
Query: 298 FDSC 301
C
Sbjct: 823 VQEC 826
Score = 67.0 bits (162), Expect = 4e-11
Identities = 41/124 (33%), Positives = 64/124 (51%), Gaps = 17/124 (13%)
Query: 190 GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249
G +CY G+G SYRG + TV C W+S + +++ E G+ N+CRNP
Sbjct: 822 GVQECYHGNGQSYRGTYSTTVTGRTCQAWSS--MTPHSHSRTPEYYPNAGL-IMNYCRNP 878
Query: 250 DADEKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPE-------ESPTE--PSTKLPG 297
D P+C+ + + V+WEYC+++ CS + VA P E+P+E P+ + PG
Sbjct: 879 DPVAAPYCYTR--DPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPG 936
Query: 298 FDSC 301
C
Sbjct: 937 VQEC 940
Score = 62.4 bits (150), Expect = 1e-09
Identities = 31/88 (35%), Positives = 48/88 (54%), Gaps = 5/88 (5%)
Query: 190 GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249
G +CY G+G SY+G TV C W+S + +++ G+ + N+CRNP
Sbjct: 936 GVQECYHGNGQSYQGTYFITVTGRTCQAWSS--MTPHSHSRTPAYYPNAGLIK-NYCRNP 992
Query: 250 DADEKPWCFIKVTNDKVKWEYCDVSACS 277
D PWC+ T+ V+WEYC+++ CS
Sbjct: 993 DPVAAPWCY--TTDPSVRWEYCNLTRCS 1018
>gi|4506143 neurotrypsin precursor [Homo sapiens]
Length = 875
Score = 162 bits (410), Expect = 8e-40
Identities = 107/267 (40%), Positives = 143/267 (53%), Gaps = 23/267 (8%)
Query: 301 CGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHF-CGGALIHPCWVLT 359
CG + R+ KRI GG S G PWQ SL+ L S G CG L+ CWVLT
Sbjct: 619 CG-LRLLHRRQKRIIGGKNSLRGGWPWQVSLR----LKSSHGDGRLLCGATLLSSCWVLT 673
Query: 360 AAHCTDI---KTRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLK 416
AAHC TR V +GD E E+ V++I + Y R + DIAL++
Sbjct: 674 AAHCFKRYGNSTRSYAVRVGDYHTLVPEEFEEEIGVQQIVIHREY--RPDRSDYDIALVR 731
Query: 417 LKPVDGHCALESKYVKTVCLP---DGSFPSGSECHISGWGVTETGKG-SRQLLDAKVKLI 472
L+ + CA S +V CLP + + S C+I+GWG +TG+ SR L A + L+
Sbjct: 732 LQGPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWG--DTGRAYSRTLQQAAIPLL 789
Query: 473 ANTLCNSRQLYDHMIDDSMICAGNLQKPGQ-DTCQGDSGGPLTCEKDG-TYYVYGIVSWG 530
C R Y M+CAGNL + + D+CQGDSGGPL CE+ G ++ VYG+ SWG
Sbjct: 790 PKRFCEER--YKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWG 847
Query: 531 LECGKR--PGVYTQVTKFLNWIKATIK 555
CG + PGVYT+V+ F+ WIK+ K
Sbjct: 848 YGCGVKDSPGVYTKVSAFVPWIKSVTK 874
Score = 47.4 bits (111), Expect = 4e-05
Identities = 17/30 (56%), Positives = 19/30 (63%)
Query: 243 HNFCRNPDADEKPWCFIKVTNDKVKWEYCD 272
HNFCR+PD +PWCF KV W YCD
Sbjct: 135 HNFCRSPDGAGRPWCFYGDARGKVDWGYCD 164
>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
Length = 529
Score = 159 bits (401), Expect = 8e-39
Identities = 103/266 (38%), Positives = 145/266 (54%), Gaps = 25/266 (9%)
Query: 300 SCGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLT 359
+CG + R+ RI GG + G PWQ SL + H CGG++I P W++T
Sbjct: 280 ACGVNLNSSRQ-SRIVGGESALPGAWPWQVSLH--------VQNVHVCGGSIITPEWIVT 330
Query: 360 AAHCTDIKTRHLKVVLGDQDLKKEEF--HEQSFRVEKIFKYSHYNERDEIPHNDIALLKL 417
AAHC + + + ++ F + ++VEK+ + +Y+ + + +NDIAL+KL
Sbjct: 331 AAHCVEKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTK--NNDIALMKL 388
Query: 418 -KPVDGHCALESKYVKTVCLPDGSFPSGSE--CHISGWGVTET-GKGSRQLLDAKVKLIA 473
KP+ + VK VCLP+ E C ISGWG TE GK S L AKV LI
Sbjct: 389 QKPLTFN-----DLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIE 443
Query: 474 NTLCNSRQLYDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLEC 533
CNSR +YD++I +MICAG LQ D+CQGDSGGPL K+ +++ G SWG C
Sbjct: 444 TQRCNSRYVYDNLITPAMICAGFLQ-GNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGC 502
Query: 534 GK--RPGVYTQVTKFLNWIKATIKSE 557
K RPGVY V F +WI ++++
Sbjct: 503 AKAYRPGVYGNVMVFTDWIYRQMRAD 528
>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
sapiens]
Length = 492
Score = 159 bits (401), Expect = 8e-39
Identities = 103/266 (38%), Positives = 145/266 (54%), Gaps = 25/266 (9%)
Query: 300 SCGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLT 359
+CG + R+ RI GG + G PWQ SL + H CGG++I P W++T
Sbjct: 243 ACGVNLNSSRQ-SRIVGGESALPGAWPWQVSLH--------VQNVHVCGGSIITPEWIVT 293
Query: 360 AAHCTDIKTRHLKVVLGDQDLKKEEF--HEQSFRVEKIFKYSHYNERDEIPHNDIALLKL 417
AAHC + + + ++ F + ++VEK+ + +Y+ + + +NDIAL+KL
Sbjct: 294 AAHCVEKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTK--NNDIALMKL 351
Query: 418 -KPVDGHCALESKYVKTVCLPDGSFPSGSE--CHISGWGVTET-GKGSRQLLDAKVKLIA 473
KP+ + VK VCLP+ E C ISGWG TE GK S L AKV LI
Sbjct: 352 QKPLTFN-----DLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIE 406
Query: 474 NTLCNSRQLYDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLEC 533
CNSR +YD++I +MICAG LQ D+CQGDSGGPL K+ +++ G SWG C
Sbjct: 407 TQRCNSRYVYDNLITPAMICAGFLQ-GNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGC 465
Query: 534 GK--RPGVYTQVTKFLNWIKATIKSE 557
K RPGVY V F +WI ++++
Sbjct: 466 AKAYRPGVYGNVMVFTDWIYRQMRAD 491
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 157 bits (398), Expect = 2e-38
Identities = 106/249 (42%), Positives = 142/249 (57%), Gaps = 31/249 (12%)
Query: 313 RIYGGFKSTAGKHPWQASLQSSLPLTISMPQG-HFCGGALIHPCWVLTAAHCT-DI---K 367
RI GG S + PWQASLQ QG H CGG++I P W++TAAHC D+ K
Sbjct: 216 RIVGGNMSLLSQWPWQASLQF---------QGYHLCGGSVITPLWIITAAHCVYDLYLPK 266
Query: 368 TRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGHCALE 427
+ ++V L + + S VEKI +S Y + NDIAL+KL G
Sbjct: 267 SWTIQVGL----VSLLDNPAPSHLVEKIVYHSKYKPKRL--GNDIALMKLA---GPLTF- 316
Query: 428 SKYVKTVCLPDG--SFPSGSECHISGWGVTETGKG--SRQLLDAKVKLIANTLCNSRQLY 483
++ ++ VCLP+ +FP G C SGWG TE G G S L A V LI+N +CN R +Y
Sbjct: 317 NEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVY 376
Query: 484 DHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECGK--RPGVYT 541
+I SM+CAG L G D+CQGDSGGPL C++ + + G S+G+ C + +PGVYT
Sbjct: 377 GGIISPSMLCAGYLTG-GVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYT 435
Query: 542 QVTKFLNWI 550
+VT FL+WI
Sbjct: 436 RVTSFLDWI 444
>gi|4503649 coagulation factor IX preproprotein [Homo sapiens]
Length = 461
Score = 155 bits (392), Expect = 9e-38
Identities = 115/410 (28%), Positives = 188/410 (45%), Gaps = 55/410 (13%)
Query: 154 CRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEIGSDDCYVGDGYSYRGKMNRTVNQH 213
C NPC NG +C + + C CP F+GK CE+ C + +G + N N+
Sbjct: 97 CESNPCLNGGSCKDDI--NSYECWCPFGFEGKNCELDVT-CNIKNGRCEQFCKNSADNKV 153
Query: 214 ACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDADEKPWCFIKVTNDKVKWEYCDV 273
C E Y + A+ + C V +
Sbjct: 154 VCS-------CTEGYRL--------------------AENQKSCEPAVPFPCGRVSVSQT 186
Query: 274 SACSAQDVAYPEESPTEPSTKLPGFDSCGKTEIAERKIKRIYGGFKSTAGKHPWQASLQS 333
S + + +P+ + D+ ++ + R+ GG + G+ PWQ L
Sbjct: 187 SKLTRAETVFPDVDYVNSTEAETILDNITQSTQSFNDFTRVVGGEDAKPGQFPWQVVLNG 246
Query: 334 SLPLTISMPQGHFCGGALIHPCWVLTAAHCTDIKTRHLKVVLGDQDLKKEEFHEQSFRVE 393
+ FCGG++++ W++TAAHC + + + VV G+ ++++ E EQ V
Sbjct: 247 KVDA--------FCGGSIVNEKWIVTAAHCVETGVK-ITVVAGEHNIEETEHTEQKRNVI 297
Query: 394 KIFKYSHYNERDEIPHNDIALLKLKPVDGHCALESKYVKTVCLPDGSFPS-----GSECH 448
+I + +YN ++DIALL+L D L S YV +C+ D + + GS +
Sbjct: 298 RIIPHHNYNAAINKYNHDIALLEL---DEPLVLNS-YVTPICIADKEYTNIFLKFGSG-Y 352
Query: 449 ISGWG-VTETGKGSRQLLDAKVKLIANTLCNSRQLYDHMIDDSMICAGNLQKPGQDTCQG 507
+SGWG V G+ + L +V L+ C + I ++M CAG + G+D+CQG
Sbjct: 353 VSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFT--IYNNMFCAG-FHEGGRDSCQG 409
Query: 508 DSGGPLTCEKDGTYYVYGIVSWGLECGKRP--GVYTQVTKFLNWIKATIK 555
DSGGP E +GT ++ GI+SWG EC + G+YT+V++++NWIK K
Sbjct: 410 DSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK 459
Score = 36.6 bits (83), Expect = 0.063
Identities = 17/65 (26%), Positives = 29/65 (44%), Gaps = 10/65 (15%)
Query: 75 DPCQPNPCEHGGDCLVHGSTFTCSCLAPFSGNKCQ----------KVQNTCKDNPCGRGQ 124
D C+ NPC +GG C +++ C C F G C+ + + CK++ +
Sbjct: 95 DQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELDVTCNIKNGRCEQFCKNSADNKVV 154
Query: 125 CLITQ 129
C T+
Sbjct: 155 CSCTE 159
>gi|118498341 chymotrypsin B1 [Homo sapiens]
Length = 263
Score = 152 bits (383), Expect = 1e-36
Identities = 98/247 (39%), Positives = 135/247 (54%), Gaps = 26/247 (10%)
Query: 311 IKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCTDIKTRH 370
+ RI G + G PWQ SLQ HFCGG+LI WV+TAAHC ++T
Sbjct: 31 LSRIVNGEDAVPGSWPWQVSLQDKTGF-------HFCGGSLISEDWVVTAAHC-GVRTSD 82
Query: 371 LKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGHCALESKY 430
+ VV G+ D +E + Q ++ K+FK ++ +NDI LLKL A S+
Sbjct: 83 V-VVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTV--NNDITLLKLATP----ARFSQT 135
Query: 431 VKTVCLP--DGSFPSGSECHISGWGVTE--TGKGSRQLLDAKVKLIANTLCNSRQLYDHM 486
V VCLP D FP+G+ C +GWG T+ K +L A + L++N C ++ +
Sbjct: 136 VSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAEC--KKSWGRR 193
Query: 487 IDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLE-CG-KRPGVYTQVT 544
I D MICAG G +C GDSGGPL C+KDG + + GIVSWG + C PGVY +VT
Sbjct: 194 ITDVMICAG---ASGVSSCMGDSGGPLVCQKDGAWTLVGIVSWGSDTCSTSSPGVYARVT 250
Query: 545 KFLNWIK 551
K + W++
Sbjct: 251 KLIPWVQ 257
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 150 bits (378), Expect = 4e-36
Identities = 98/271 (36%), Positives = 141/271 (52%), Gaps = 26/271 (9%)
Query: 295 LPGFDSCGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHP 354
+P CG E K R+ GGF + +G+ PWQ SL+ HFCG ++
Sbjct: 486 VPKLQECGARPAME-KPTRVVGGFGAASGEVPWQVSLKEG--------SRHFCGATVVGD 536
Query: 355 CWVLTAAHCTD-IKTRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIA 413
W+L+AAHC + K ++ LG L + ++ + YN I D+A
Sbjct: 537 RWLLSAAHCFNHTKVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPG--ILDFDLA 594
Query: 414 LLKLKPVDGHCALESKYVKTVCLPDG--SFPSGSECHISGWGVTETGKGSRQ--LLDAKV 469
+L+L +KY++ VCLP FP G +C ISGWG T+ G ++ L A V
Sbjct: 595 VLELASPLAF----NKYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASV 650
Query: 470 KLIANTLCNSRQLYDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEK-DGTYYVYGIVS 528
+I C+ LY+ + D MICAG L+ D+CQGDSGGPL CE+ G +Y+ GIVS
Sbjct: 651 GIIDQKTCSV--LYNFSLTDRMICAGFLEGK-VDSCQGDSGGPLACEEAPGVFYLAGIVS 707
Query: 529 WGLECG--KRPGVYTQVTKFLNWIKATIKSE 557
WG+ C K+PGVYT++T+ WI + S+
Sbjct: 708 WGIGCAQVKKPGVYTRITRLKGWILEIMSSQ 738
Score = 144 bits (364), Expect = 2e-34
Identities = 101/267 (37%), Positives = 147/267 (55%), Gaps = 30/267 (11%)
Query: 301 CGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTA 360
CG + A R RI GG +++ G+ PWQASL+ + + HFCG A+I+ W+++A
Sbjct: 191 CG-LQPAWRMAGRIVGGMEASPGEFPWQASLREN--------KEHFCGAAIINARWLVSA 241
Query: 361 AHCTDIKTRHLKVV--LGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKL- 417
AHC + K V +G L E +V +I K+ YN + D+A+L+L
Sbjct: 242 AHCFNEFQDPTKWVAYVGATYLSGSEASTVRAQVVQIVKHPLYNA--DTADFDVAVLELT 299
Query: 418 KPVDGHCALESKYVKTVCLPDGS--FPSGSECHISGWGVTETG--KGSRQLLDAKVKLIA 473
P+ ++++ VCLP + FP +C ISGWG + L A V+L+
Sbjct: 300 SPLP-----FGRHIQPVCLPAATHIFPPSKKCLISGWGYLKEDFLVKPEVLQKATVELLD 354
Query: 474 NTLCNSRQLYDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEK-DGTYYVYGIVSWGLE 532
LC S LY H + D M+CAG L D+CQGDSGGPL CE+ G +++ GIVSWG+
Sbjct: 355 QALCAS--LYGHSLTDRMVCAGYLDGK-VDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIG 411
Query: 533 C--GKRPGVYTQVTKFLNWI-KATIKS 556
C +RPGVY +VT+ +WI +AT K+
Sbjct: 412 CAEARRPGVYARVTRLRDWILEATTKA 438
Score = 141 bits (355), Expect = 2e-33
Identities = 106/305 (34%), Positives = 147/305 (48%), Gaps = 34/305 (11%)
Query: 255 PWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDSCGKTEIAERKIKRI 314
P +VT VS + +P+ T+LP CG +A + RI
Sbjct: 774 PGAASRVTGQPANSTLSAVSTTARGQTPFPDAPEATTHTQLP---DCG---LAPAALTRI 827
Query: 315 YGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCTDI--KTRHLK 372
GG + G+ PWQ SL + H CG L+ W+L+AAHC D+ +
Sbjct: 828 VGGSAAGRGEWPWQVSLWLRR-------REHRCGAVLVAERWLLSAAHCFDVYGDPKQWA 880
Query: 373 VVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLK-PVDGHCALESKYV 431
LG L E Q RV +I+K+ YN D+ALL+L PV S+ V
Sbjct: 881 AFLGTPFLSGAE--GQLERVARIYKHPFYNL--YTLDYDVALLELAGPV-----RRSRLV 931
Query: 432 KTVCLPDGS--FPSGSECHISGWG-VTETGKGSRQLLDAKVKLIANTLCNSRQLYDHMID 488
+ +CLP+ + P G+ C I+GWG V E G +RQL A V+L++ C R+ Y I
Sbjct: 932 RPICLPEPAPRPPDGTRCVITGWGSVREGGSMARQLQKAAVRLLSEQTC--RRFYPVQIS 989
Query: 489 DSMICAGNLQKPGQDTCQGDSGGPLTC-EKDGTYYVYGIVSWGLECGKR--PGVYTQVTK 545
M+CAG + G D+C GD+GGPL C E G + + G+ SWG CG+ PGVYT+V
Sbjct: 990 SRMLCAG-FPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAA 1048
Query: 546 FLNWI 550
WI
Sbjct: 1049 VRGWI 1053
>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
Length = 275
Score = 149 bits (375), Expect = 9e-36
Identities = 99/255 (38%), Positives = 141/255 (55%), Gaps = 36/255 (14%)
Query: 314 IYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCT--DIKT-RH 370
I GG ++ K PWQ SL+ P + HFCGG+LIHP WVLTAAHC D+K
Sbjct: 31 IVGGQEAPRSKWPWQVSLRVHGPYWM-----HFCGGSLIHPQWVLTAAHCVGPDVKDLAA 85
Query: 371 LKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLK-PVDGHCALESK 429
L+V L +Q L + +Q V +I + + DIALL+L+ PV+ S
Sbjct: 86 LRVQLREQHLY---YQDQLLPVSRIIVHPQFYTAQI--GADIALLELEEPVN-----VSS 135
Query: 430 YVKTVCLPDGS--FPSGSECHISGWGVTETGKGSRQ---LLDAKVKLIANTLCNSRQLYD 484
+V TV LP S FP G C ++GWG + + L KV ++ N +C+++
Sbjct: 136 HVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLG 195
Query: 485 -------HMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECGK-- 535
++ D M+CAGN ++ D+CQGDSGGPL C+ +GT+ G+VSWG C +
Sbjct: 196 AYTGDDVRIVRDDMLCAGNTRR---DSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPN 252
Query: 536 RPGVYTQVTKFLNWI 550
RPG+YT+VT +L+WI
Sbjct: 253 RPGIYTRVTYYLDWI 267
>gi|148613878 acrosin precursor [Homo sapiens]
Length = 421
Score = 148 bits (373), Expect = 1e-35
Identities = 103/263 (39%), Positives = 141/263 (53%), Gaps = 28/263 (10%)
Query: 313 RIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCTDIK--TRH 370
RI GG + G PW SLQ T + + H CGG+L++ WVLTAAHC K
Sbjct: 42 RIVGGKAAQHGAWPWMVSLQI---FTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHD 98
Query: 371 LKVVLGDQDL-----KKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGHCA 425
++V G +++ K + Q VEKI + YN E NDIAL+++ P C
Sbjct: 99 WRLVFGAKEITYGNNKPVKAPLQERYVEKIIIHEKYNSATE--GNDIALVEITPPIS-C- 154
Query: 426 LESKYVKTVCLP--DGSFPSGSE-CHISGWGVTE--TGKGSRQLLDAKVKLIANTLCNSR 480
+++ CLP P GS+ C ++GWG E + S L++A+V LI LCNS
Sbjct: 155 --GRFIGPGCLPHFKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNST 212
Query: 481 QLYDHMIDDSMICAGNLQKPGQ-DTCQGDSGGPLTCE--KDGTYYVYGIVSWGLEC--GK 535
Q Y+ + + +CAG G+ DTCQGDSGGPL C+ K+ Y V GI SWG+ C K
Sbjct: 213 QWYNGRVQPTNVCAG--YPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAK 270
Query: 536 RPGVYTQVTKFLNWIKATIKSES 558
RPG+YT +LNWI + I S +
Sbjct: 271 RPGIYTATWPYLNWIASKIGSNA 293
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 148 bits (373), Expect = 1e-35
Identities = 99/259 (38%), Positives = 138/259 (53%), Gaps = 30/259 (11%)
Query: 313 RIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCTDIKTRHL- 371
RI GG ++ K PWQ SL H CGG LI WVLTAAHC + +
Sbjct: 325 RIVGGALASDSKWPWQVSLHFGTT--------HICGGTLIDAQWVLTAAHCFFVTREKVL 376
Query: 372 ---KVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKL-KPVDGHCALE 427
KV G +L + E + E I ++ +E D+ DIAL++L KP+
Sbjct: 377 EGWKVYAGTSNL--HQLPEAASIAEIIINSNYTDEEDDY---DIALMRLSKPLT-----L 426
Query: 428 SKYVKTVCLP--DGSFPSGSECHISGWGVTET--GKGSRQLLDAKVKLIANTLCNSRQLY 483
S ++ CLP +F C I+G+G T K S L + +V LI CN +Y
Sbjct: 427 SAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVY 486
Query: 484 DHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECGKR--PGVYT 541
D + M+CAG+L + G+D+CQGDSGGPL CE++ +Y+ G+ SWG CG+R PGVYT
Sbjct: 487 DSYLTPRMMCAGDL-RGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYT 545
Query: 542 QVTKFLNWIKATIKSESGF 560
+VT+ L WI + ++SE F
Sbjct: 546 KVTEVLPWIYSKMESEVRF 564
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 147 bits (371), Expect = 3e-35
Identities = 92/258 (35%), Positives = 136/258 (52%), Gaps = 32/258 (12%)
Query: 313 RIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHC--TDIKTRH 370
RI GG + AG+ PWQ S I+ H CGG+L+ WVL+AAHC ++
Sbjct: 44 RITGGSSAVAGQWPWQVS--------ITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEA 95
Query: 371 LKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKL-KPVDGHCALESK 429
+V LG L + ++ I + Y + E DIALL+L +P+ S+
Sbjct: 96 YEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQ--EGSQGDIALLQLSRPITF-----SR 148
Query: 430 YVKTVCLP--DGSFPSGSECHISGWGVTETGKG---SRQLLDAKVKLIANTLCNSRQLYD 484
Y++ +CLP + SFP+G C ++GWG + L +V LI+ CN D
Sbjct: 149 YIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNID 208
Query: 485 ------HMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECG--KR 536
H + + M+CAG ++ G+D CQGDSGGPL+C +G +Y+ GIVSWG CG R
Sbjct: 209 AKPEEPHFVQEDMVCAGYVEG-GKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNR 267
Query: 537 PGVYTQVTKFLNWIKATI 554
PGVYT + + +WI++ +
Sbjct: 268 PGVYTLASSYASWIQSKV 285
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 147 bits (370), Expect = 3e-35
Identities = 102/253 (40%), Positives = 139/253 (54%), Gaps = 29/253 (11%)
Query: 313 RIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHC----TDIKT 368
RI GG S+ G+ PWQASLQ + H CGGALI WV+TAAHC + T
Sbjct: 576 RIVGGAVSSEGEWPWQASLQ--------VRGRHICGGALIADRWVITAAHCFQEDSMAST 627
Query: 369 RHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGHCALES 428
V LG E SF+V ++ + Y+E D + D+ALL+L H + S
Sbjct: 628 VLWTVFLGKVWQNSRWPGEVSFKVSRLLLHP-YHEEDSHDY-DVALLQL----DHPVVRS 681
Query: 429 KYVKTVCLPDGS--FPSGSECHISGWG-VTETGKGSRQLLDAKVKLIANTLCNSRQLYDH 485
V+ VCLP S F G C I+GWG + E G S L V+LI LC+ ++Y +
Sbjct: 682 AAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCS--EVYRY 739
Query: 486 MIDDSMICAGNLQKPGQDTCQGDSGGPLTCEK-DGTYYVYGIVSWGLECGKRP---GVYT 541
+ M+CAG +K +D CQGDSGGPL C+ G +++ G+VSWGL CG RP GVYT
Sbjct: 740 QVTPRMLCAG-YRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCG-RPNYFGVYT 797
Query: 542 QVTKFLNWIKATI 554
++T ++WI+ +
Sbjct: 798 RITGVISWIQQVV 810
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 146 bits (369), Expect = 4e-35
Identities = 105/319 (32%), Positives = 161/319 (50%), Gaps = 41/319 (12%)
Query: 252 DEKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDSCGKTEIAERKI 311
+EK CF++++ D S +AY + + S +L + G + K
Sbjct: 342 EEKCKCFLRLSMDG-----------SPTRIAYGTQGSSGYSLRLC---NTGDNSVCTTKT 387
Query: 312 K-RIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCTDIKT-- 368
RI GG S+ G+ PWQ SLQ L Q H CGG+LI WVLTAAHC D
Sbjct: 388 STRIVGGTNSSWGEWPWQVSLQVKLTA-----QRHLCGGSLIGHQWVLTAAHCFDGLPLQ 442
Query: 369 ---RHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGHCA 425
R +L D+ K+ Q +++I + +Y + ++DIAL+KL+ +
Sbjct: 443 DVWRIYSGILNLSDITKDTPFSQ---IKEIIIHQNYKVSEG--NHDIALIKLQAPLNY-- 495
Query: 426 LESKYVKTVCLPDGSFPSG--SECHISGWGVT-ETGKGSRQLLDAKVKLIANTLCNSRQL 482
+++ K +CLP S + C ++GWG + E G+ L + L+ N C R
Sbjct: 496 --TEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRY- 552
Query: 483 YDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECGKR--PGVY 540
D+ I M+CAG ++ G+D C+GDSGGPL C+ +G + + GI SWG C +R PGVY
Sbjct: 553 QDYKITQRMVCAG-YKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVY 611
Query: 541 TQVTKFLNWIKATIKSESG 559
T+V ++++WI +S G
Sbjct: 612 TKVAEYMDWILEKTQSSDG 630
>gi|118498350 chymotrypsin B2 [Homo sapiens]
Length = 263
Score = 146 bits (369), Expect = 4e-35
Identities = 96/247 (38%), Positives = 132/247 (53%), Gaps = 26/247 (10%)
Query: 311 IKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCTDIKTRH 370
+ RI G + G PWQ SLQ HFCGG+LI WV+TAAHC ++T
Sbjct: 31 LSRIVNGEDAVPGSWPWQVSLQDKTGF-------HFCGGSLISEDWVVTAAHC-GVRTSD 82
Query: 371 LKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGHCALESKY 430
+ VV G+ D +E + Q ++ K+FK ++ +NDI LLKL A S+
Sbjct: 83 V-VVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTV--NNDITLLKLATP----ARFSQT 135
Query: 431 VKTVCLP--DGSFPSGSECHISGWGVTE--TGKGSRQLLDAKVKLIANTLCNSRQLYDHM 486
V VCLP D FP+G+ C +GWG T+ K +L A + L++N C ++ +
Sbjct: 136 VSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAEC--KKSWGRR 193
Query: 487 IDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLE-CG-KRPGVYTQVT 544
I D MICAG G +C GDSGGPL C+KDG + + GIVSWG C P VY +V
Sbjct: 194 ITDVMICAG---ASGVSSCMGDSGGPLVCQKDGAWTLVGIVSWGSRTCSTTTPAVYARVA 250
Query: 545 KFLNWIK 551
K + W++
Sbjct: 251 KLIPWVQ 257
>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
Length = 418
Score = 146 bits (369), Expect = 4e-35
Identities = 92/248 (37%), Positives = 135/248 (54%), Gaps = 27/248 (10%)
Query: 312 KRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHC--TDIKTR 369
+RI GG ++ G PWQ SL+ + H CGG+LI+ W+LTAAHC ++ R
Sbjct: 185 QRILGGTEAEEGSWPWQVSLR--------LNNAHHCGGSLINNMWILTAAHCFRSNSNPR 236
Query: 370 HLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGHCALESK 429
G F + RV I H N + NDIAL++L+ + +K
Sbjct: 237 DWIATSG----ISTTFPKLRMRVRNIL--IHNNYKSATHENDIALVRLE----NSVTFTK 286
Query: 430 YVKTVCLPDG--SFPSGSECHISGWGVTE-TGKGSRQLLDAKVKLIANTLCNSRQLYDHM 486
+ +VCLP + P GS +++GWG E G +L +V++I+N +CN+ Y+
Sbjct: 287 DIHSVCLPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGA 346
Query: 487 IDDSMICAGNLQKPGQDTCQGDSGGPLTCEKD-GTYYVYGIVSWGLECG--KRPGVYTQV 543
I M+CAG + + G D CQGDSGGPL E +++ GIVSWG +CG +PGVYT+V
Sbjct: 347 ILSGMLCAG-VPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRV 405
Query: 544 TKFLNWIK 551
T +L+WI+
Sbjct: 406 TAYLDWIR 413
>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
Length = 275
Score = 145 bits (366), Expect = 1e-34
Identities = 98/255 (38%), Positives = 140/255 (54%), Gaps = 36/255 (14%)
Query: 314 IYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCT--DIKT-RH 370
I GG ++ K PWQ SL+ + HFCGG+LIHP WVLTAAHC D+K
Sbjct: 31 IVGGQEAPRSKWPWQVSLRVRDRYWM-----HFCGGSLIHPQWVLTAAHCVGPDVKDLAA 85
Query: 371 LKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLK-PVDGHCALESK 429
L+V L +Q L + +Q V +I + + DIALL+L+ PV+ S
Sbjct: 86 LRVQLREQHLY---YQDQLLPVSRIIVHPQFYTAQI--GADIALLELEEPVN-----VSS 135
Query: 430 YVKTVCLPDGS--FPSGSECHISGWGVTETGKGSRQ---LLDAKVKLIANTLCNSRQLYD 484
+V TV LP S FP G C ++GWG + + L KV ++ N +C+++
Sbjct: 136 HVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLG 195
Query: 485 -------HMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECGK-- 535
++ D M+CAGN ++ D+CQGDSGGPL C+ +GT+ G+VSWG C +
Sbjct: 196 AYTGDDVRIVRDDMLCAGNTRR---DSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPN 252
Query: 536 RPGVYTQVTKFLNWI 550
RPG+YT+VT +L+WI
Sbjct: 253 RPGIYTRVTYYLDWI 267
>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
sapiens]
Length = 432
Score = 144 bits (363), Expect = 2e-34
Identities = 102/268 (38%), Positives = 142/268 (52%), Gaps = 36/268 (13%)
Query: 300 SCGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLT 359
+CGK+ K R+ GG +++ PWQ S+Q + H CGG+++ P WVLT
Sbjct: 190 ACGKS----LKTPRVVGGEEASVDSWPWQVSIQYD--------KQHVCGGSILDPHWVLT 237
Query: 360 AAHC----TDIKTRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALL 415
AAHC TD+ + KV G K F + I +++ +D NDIAL+
Sbjct: 238 AAHCFRKHTDV--FNWKVRAGSD--KLGSFPSLAVAKIIIIEFNPMYPKD----NDIALM 289
Query: 416 KLKPVDGHCALESKYVKTVCLP--DGSFPSGSECHISGWGVTET--GKGSRQLLDAKVKL 471
KL+ S V+ +CLP D + I GWG T+ GK S LL A V++
Sbjct: 290 KLQ----FPLTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQV 345
Query: 472 IANTLCNSRQLYDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGL 531
I +T CN+ Y + + M+CAG + + G DTCQGDSGGPL + D ++V GIVSWG
Sbjct: 346 IDSTRCNADDAYQGEVTEKMMCAG-IPEGGVDTCQGDSGGPLMYQSD-QWHVVGIVSWGY 403
Query: 532 ECG--KRPGVYTQVTKFLNWIKATIKSE 557
CG PGVYT+V+ +LNWI K+E
Sbjct: 404 GCGGPSTPGVYTKVSAYLNWIYNVWKAE 431
>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
sapiens]
Length = 437
Score = 144 bits (363), Expect = 2e-34
Identities = 102/268 (38%), Positives = 142/268 (52%), Gaps = 36/268 (13%)
Query: 300 SCGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLT 359
+CGK+ K R+ GG +++ PWQ S+Q + H CGG+++ P WVLT
Sbjct: 195 ACGKS----LKTPRVVGGEEASVDSWPWQVSIQYD--------KQHVCGGSILDPHWVLT 242
Query: 360 AAHC----TDIKTRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALL 415
AAHC TD+ + KV G K F + I +++ +D NDIAL+
Sbjct: 243 AAHCFRKHTDV--FNWKVRAGSD--KLGSFPSLAVAKIIIIEFNPMYPKD----NDIALM 294
Query: 416 KLKPVDGHCALESKYVKTVCLP--DGSFPSGSECHISGWGVTET--GKGSRQLLDAKVKL 471
KL+ S V+ +CLP D + I GWG T+ GK S LL A V++
Sbjct: 295 KLQ----FPLTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQV 350
Query: 472 IANTLCNSRQLYDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGL 531
I +T CN+ Y + + M+CAG + + G DTCQGDSGGPL + D ++V GIVSWG
Sbjct: 351 IDSTRCNADDAYQGEVTEKMMCAG-IPEGGVDTCQGDSGGPLMYQSD-QWHVVGIVSWGY 408
Query: 532 ECG--KRPGVYTQVTKFLNWIKATIKSE 557
CG PGVYT+V+ +LNWI K+E
Sbjct: 409 GCGGPSTPGVYTKVSAYLNWIYNVWKAE 436
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 142 bits (357), Expect = 1e-33
Identities = 96/263 (36%), Positives = 130/263 (49%), Gaps = 30/263 (11%)
Query: 301 CGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTA 360
CG +A R I GG G+ PWQAS +++ H CGG+++ P WV+TA
Sbjct: 209 CGARPLASR----IVGGQSVAPGRWPWQAS--------VALGFRHTCGGSVLAPRWVVTA 256
Query: 361 AHCTD----IKTRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLK 416
AHC + +V G H+ + VE+I + Y+ ++ D+ALL+
Sbjct: 257 AHCMHSFRLARLSSWRVHAGLVSHSAVRPHQGAL-VERIIPHPLYSAQNH--DYDVALLR 313
Query: 417 LKPVDGHCALESKYVKTVCLP--DGSFPSGSECHISGWGVTETGK--GSRQLLDAKVKLI 472
L+ S V VCLP + FP GS C +SGWG T S L D V L
Sbjct: 314 LQTALNF----SDTVGAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLF 369
Query: 473 ANTLCNSRQLYDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLE 532
+ LCNS +Y + M+CAG L D CQGDSGGPL C T+ + G+VSWG
Sbjct: 370 STQLCNSSCVYSGALTPRMLCAGYLDGRA-DACQGDSGGPLVCPDGDTWRLVGVVSWGRG 428
Query: 533 CGK--RPGVYTQVTKFLNWIKAT 553
C + PGVY +V +FL+WI T
Sbjct: 429 CAEPNHPGVYAKVAEFLDWIHDT 451
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 141 bits (355), Expect = 2e-33
Identities = 95/256 (37%), Positives = 140/256 (54%), Gaps = 32/256 (12%)
Query: 307 AERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHF-CGGALIHPCWVLTAAHCTD 365
AE + K ++GG HP+QA+L +S GH CGG LIHP WVLTAAHC
Sbjct: 16 AEEQNKLVHGG-PCDKTSHPYQAALYTS---------GHLLCGGVLIHPLWVLTAAHC-- 63
Query: 366 IKTRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHN-DIALLKLKPVDGHC 424
K +L+V LG +L++ E ++ V + + Y D H+ DI LL+L
Sbjct: 64 -KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDY---DAASHDQDIMLLRL----ARP 115
Query: 425 ALESKYVKTVCLPDGSFPSGSECHISGWGVTETGKGSRQLLDAKVKLIANTLCNSRQLYD 484
A S+ ++ + L + + CHI GWG T G + A + L++ C Y
Sbjct: 116 AKLSELIQPLPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREEC--EHAYP 173
Query: 485 HMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWG-LECG--KRPGVYT 541
I +M+CAG+ +K G+D+CQGDSGGPL C ++ G+VSWG + CG ++PGVYT
Sbjct: 174 GQITQNMLCAGD-EKYGKDSCQGDSGGPLVCGD----HLRGLVSWGNIPCGSKEKPGVYT 228
Query: 542 QVTKFLNWIKATIKSE 557
V ++ NWI+ TI+++
Sbjct: 229 NVCRYTNWIQKTIQAK 244
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 141 bits (355), Expect = 2e-33
Identities = 95/256 (37%), Positives = 140/256 (54%), Gaps = 32/256 (12%)
Query: 307 AERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHF-CGGALIHPCWVLTAAHCTD 365
AE + K ++GG HP+QA+L +S GH CGG LIHP WVLTAAHC
Sbjct: 16 AEEQNKLVHGG-PCDKTSHPYQAALYTS---------GHLLCGGVLIHPLWVLTAAHC-- 63
Query: 366 IKTRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHN-DIALLKLKPVDGHC 424
K +L+V LG +L++ E ++ V + + Y D H+ DI LL+L
Sbjct: 64 -KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDY---DAASHDQDIMLLRL----ARP 115
Query: 425 ALESKYVKTVCLPDGSFPSGSECHISGWGVTETGKGSRQLLDAKVKLIANTLCNSRQLYD 484
A S+ ++ + L + + CHI GWG T G + A + L++ C Y
Sbjct: 116 AKLSELIQPLPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREEC--EHAYP 173
Query: 485 HMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWG-LECG--KRPGVYT 541
I +M+CAG+ +K G+D+CQGDSGGPL C ++ G+VSWG + CG ++PGVYT
Sbjct: 174 GQITQNMLCAGD-EKYGKDSCQGDSGGPLVCGD----HLRGLVSWGNIPCGSKEKPGVYT 228
Query: 542 QVTKFLNWIKATIKSE 557
V ++ NWI+ TI+++
Sbjct: 229 NVCRYTNWIQKTIQAK 244
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,414,403
Number of Sequences: 37866
Number of extensions: 1299701
Number of successful extensions: 6044
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 269
Number of HSP's successfully gapped in prelim test: 162
Number of HSP's that attempted gapping in prelim test: 3002
Number of HSP's gapped (non-prelim): 1458
length of query: 560
length of database: 18,247,518
effective HSP length: 107
effective length of query: 453
effective length of database: 14,195,856
effective search space: 6430722768
effective search space used: 6430722768
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.