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Search of human proteins with 4758410
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758410 fragile X mental retardation syndrome related
protein 2 [Homo sapiens]
(673 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758410 fragile X mental retardation syndrome related protein... 1350 0.0
gi|61835148 fragile X mental retardation-related protein 1 isofo... 734 0.0
gi|61835164 fragile X mental retardation-related protein 1 isofo... 713 0.0
gi|61835172 fragile X mental retardation-related protein 1 isofo... 586 e-167
gi|4503765 fragile X mental retardation 1 [Homo sapiens] 485 e-137
gi|50083281 KIAA1853 protein [Homo sapiens] 53 8e-07
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 52 2e-06
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 51 4e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 50 7e-06
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 49 2e-05
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 49 2e-05
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 49 2e-05
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 48 3e-05
gi|239751791 PREDICTED: hypothetical protein [Homo sapiens] 48 3e-05
gi|239746282 PREDICTED: hypothetical protein XP_002343723 [Homo ... 48 3e-05
gi|169164483 PREDICTED: hypothetical protein [Homo sapiens] 47 4e-05
gi|113414226 PREDICTED: hypothetical protein [Homo sapiens] 47 4e-05
gi|239743051 PREDICTED: hypothetical protein XP_002342747 [Homo ... 47 4e-05
gi|113413437 PREDICTED: hypothetical protein [Homo sapiens] 47 4e-05
gi|60097902 filaggrin [Homo sapiens] 46 1e-04
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 46 1e-04
gi|239757337 PREDICTED: hypothetical protein XP_002345251 [Homo ... 45 2e-04
gi|239751874 PREDICTED: hypothetical protein XP_002348034 [Homo ... 45 2e-04
gi|239754474 PREDICTED: similar to mucin [Homo sapiens] 45 2e-04
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 45 3e-04
gi|50962882 G patch domain containing 8 [Homo sapiens] 45 3e-04
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 44 4e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 44 4e-04
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 44 4e-04
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 44 4e-04
>gi|4758410 fragile X mental retardation syndrome related protein 2
[Homo sapiens]
Length = 673
Score = 1350 bits (3495), Expect = 0.0
Identities = 673/673 (100%), Positives = 673/673 (100%)
Query: 1 MGGLASGGDVEPGLPVEVRGSNGAFYKGFVKDVHEDSVTIFFENNWQSERQIPFGDVRLP 60
MGGLASGGDVEPGLPVEVRGSNGAFYKGFVKDVHEDSVTIFFENNWQSERQIPFGDVRLP
Sbjct: 1 MGGLASGGDVEPGLPVEVRGSNGAFYKGFVKDVHEDSVTIFFENNWQSERQIPFGDVRLP 60
Query: 61 PPADYNKEITEGDEVEVYSRANEQEPCGWWLARVRMMKGDFYVIEYAACDATYNEIVTLE 120
PPADYNKEITEGDEVEVYSRANEQEPCGWWLARVRMMKGDFYVIEYAACDATYNEIVTLE
Sbjct: 61 PPADYNKEITEGDEVEVYSRANEQEPCGWWLARVRMMKGDFYVIEYAACDATYNEIVTLE 120
Query: 121 RLRPVNPNPLATKGSFFKVTMAVPEDLREACSNENVHKEFKKALGANCIFLNITNSELFI 180
RLRPVNPNPLATKGSFFKVTMAVPEDLREACSNENVHKEFKKALGANCIFLNITNSELFI
Sbjct: 121 RLRPVNPNPLATKGSFFKVTMAVPEDLREACSNENVHKEFKKALGANCIFLNITNSELFI 180
Query: 181 LSTTEAPVKRASLLGDMHFRSLRTKLLLMSRNEEATKHLETSKQLAAAFQEEFTVREDLM 240
LSTTEAPVKRASLLGDMHFRSLRTKLLLMSRNEEATKHLETSKQLAAAFQEEFTVREDLM
Sbjct: 181 LSTTEAPVKRASLLGDMHFRSLRTKLLLMSRNEEATKHLETSKQLAAAFQEEFTVREDLM 240
Query: 241 GLAIGTHGANIQQARKVPGVTAIELGEETCTFRIYGETPEACRQARSYLEFSEDSVQVPR 300
GLAIGTHGANIQQARKVPGVTAIELGEETCTFRIYGETPEACRQARSYLEFSEDSVQVPR
Sbjct: 241 GLAIGTHGANIQQARKVPGVTAIELGEETCTFRIYGETPEACRQARSYLEFSEDSVQVPR 300
Query: 301 NLVGKVIGKNGKVIQEIVDKSGVVRVRVEGDNDKKNPREEGMVPFIFVGTRENISNAQAL 360
NLVGKVIGKNGKVIQEIVDKSGVVRVRVEGDNDKKNPREEGMVPFIFVGTRENISNAQAL
Sbjct: 301 NLVGKVIGKNGKVIQEIVDKSGVVRVRVEGDNDKKNPREEGMVPFIFVGTRENISNAQAL 360
Query: 361 LEYHLSYLQEVEQLRLERLQIDEQLRQIGLGFRPPGSGRGSGGSDKAGYSTDESSSSSLH 420
LEYHLSYLQEVEQLRLERLQIDEQLRQIGLGFRPPGSGRGSGGSDKAGYSTDESSSSSLH
Sbjct: 361 LEYHLSYLQEVEQLRLERLQIDEQLRQIGLGFRPPGSGRGSGGSDKAGYSTDESSSSSLH 420
Query: 421 ATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRDPPTRGEES 480
ATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRDPPTRGEES
Sbjct: 421 ATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRDPPTRGEES 480
Query: 481 RRRPTGGRGRGPPPAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPP 540
RRRPTGGRGRGPPPAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPP
Sbjct: 481 RRRPTGGRGRGPPPAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPP 540
Query: 541 ASARRRRSRRRRTDEDRTVMDGGLESDGPNMTENGLEDESRPQRRNRSRRRRNRGNRTDG 600
ASARRRRSRRRRTDEDRTVMDGGLESDGPNMTENGLEDESRPQRRNRSRRRRNRGNRTDG
Sbjct: 541 ASARRRRSRRRRTDEDRTVMDGGLESDGPNMTENGLEDESRPQRRNRSRRRRNRGNRTDG 600
Query: 601 SISGDRQPVTVADYISRAESQSRQSAPLERTKPSEDSLSGQKGDSVSKLPKGPSENGELS 660
SISGDRQPVTVADYISRAESQSRQSAPLERTKPSEDSLSGQKGDSVSKLPKGPSENGELS
Sbjct: 601 SISGDRQPVTVADYISRAESQSRQSAPLERTKPSEDSLSGQKGDSVSKLPKGPSENGELS 660
Query: 661 APLELGSMVNGVS 673
APLELGSMVNGVS
Sbjct: 661 APLELGSMVNGVS 673
>gi|61835148 fragile X mental retardation-related protein 1 isoform
a [Homo sapiens]
Length = 621
Score = 734 bits (1896), Expect = 0.0
Identities = 409/696 (58%), Positives = 478/696 (68%), Gaps = 114/696 (16%)
Query: 14 LPVEVRGSNGAFYKGFVKDVHEDSVTIFFENNWQSERQIPFGDVRLPPPADYNKEITEGD 73
L VEVRGSNGAFYKGF+KDVHEDS+T+ FENNWQ ERQ+PF +VRLPPP D KEI+EGD
Sbjct: 4 LTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEISEGD 63
Query: 74 EVEVYSRANEQEPCGWWLARVRMMKGDFYVIEYAACDATYNEIVTLERLRPVNPNPLATK 133
EVEVYSRAN+QEPCGWWLA+VRMMKG+FYVIEYAACDATYNEIVT ERLRPVN N K
Sbjct: 64 EVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKK 123
Query: 134 GSFFKVTMAVPEDLREACSNENVHKEFKKALGANCIFLNITNSELFILSTTEAPVKRASL 193
+FFK T+ VPEDLREAC+NEN HK+FKKA+GA IF + ++L ILS +EA VKR ++
Sbjct: 124 NTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNI 183
Query: 194 LGDMHFRSLRTKLLLMSRNEEATKHLETSKQLAAAFQEEFTVREDLMGLAIGTHGANIQQ 253
L DMH RS+RTKL+LMSRNEEATKHLE +KQLAAAF EEF VREDLMGLAIGTHG+NIQQ
Sbjct: 184 LSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQ 243
Query: 254 ARKVPGVTAIELGEETCTFRIYGETPEACRQARSYLEFSEDSVQVPRNLVGKVIGKNGKV 313
ARKVPGVTAIEL E+T TFRIYGE+ +A ++AR +LEF ED +QVPRNLVGKVIGKNGKV
Sbjct: 244 ARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKV 303
Query: 314 IQEIVDKSGVVRVRVEGDNDKKNPREEGMVPFIFVGTRENISNAQALLEYHLSYLQEVEQ 373
IQEIVDKSGVVRVR+EGDN+ K PRE+GMVPF+FVGT+E+I N Q LLEYH++YL+EVEQ
Sbjct: 304 IQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQ 363
Query: 374 LRLERLQIDEQLRQIGLGFRPPGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRG 433
LR+ERLQIDEQLRQIG SY GRG
Sbjct: 364 LRMERLQIDEQLRQIG------------------------------------SRSYSGRG 387
Query: 434 RGRRTGGP----AYGPSSDVSTASETESEKREEP---NRAGPGDRDPPTRGEESRRRP-- 484
RGRR GP YG +S++S SETESE+++E + AG DRD +SRRRP
Sbjct: 388 RGRR--GPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRD-SRHQRDSRRRPGG 444
Query: 485 -----TGGRGRGPPPAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPP 539
+GGRGRG P R SSISSVLKDPDSNPYSLLD +E + D++ E
Sbjct: 445 RGRSVSGGRGRGGP-------RGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESH 497
Query: 540 PASARRRRSRRRRTDEDRTVMDGGLESDGPNMTENGLEDESRPQRRNRSRRRRNRGNRTD 599
++ RRRRSRRRRTDED +MDG ESD ++ ENGL
Sbjct: 498 HSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGL----------------------- 534
Query: 600 GSISGDRQPVTVADYISRAESQSRQ----------------SAPLERTKPSEDSLSG--- 640
VTVADYISRAESQSRQ +E PSE +++G
Sbjct: 535 ---------VTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTS 585
Query: 641 QKGDSVSKLPKGPSE---NGELSAPLELGSMVNGVS 673
GD +SKL + P E N + +++NGVS
Sbjct: 586 ASGDDISKLQRTPGEEKINTLKEENTQEAAVLNGVS 621
>gi|61835164 fragile X mental retardation-related protein 1 isoform
b [Homo sapiens]
Length = 539
Score = 713 bits (1840), Expect = 0.0
Identities = 376/577 (65%), Positives = 435/577 (75%), Gaps = 60/577 (10%)
Query: 14 LPVEVRGSNGAFYKGFVKDVHEDSVTIFFENNWQSERQIPFGDVRLPPPADYNKEITEGD 73
L VEVRGSNGAFYKGF+KDVHEDS+T+ FENNWQ ERQ+PF +VRLPPP D KEI+EGD
Sbjct: 4 LTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEISEGD 63
Query: 74 EVEVYSRANEQEPCGWWLARVRMMKGDFYVIEYAACDATYNEIVTLERLRPVNPNPLATK 133
EVEVYSRAN+QEPCGWWLA+VRMMKG+FYVIEYAACDATYNEIVT ERLRPVN N K
Sbjct: 64 EVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKK 123
Query: 134 GSFFKVTMAVPEDLREACSNENVHKEFKKALGANCIFLNITNSELFILSTTEAPVKRASL 193
+FFK T+ VPEDLREAC+NEN HK+FKKA+GA IF + ++L ILS +EA VKR ++
Sbjct: 124 NTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNI 183
Query: 194 LGDMHFRSLRTKLLLMSRNEEATKHLETSKQLAAAFQEEFTVREDLMGLAIGTHGANIQQ 253
L DMH RS+RTKL+LMSRNEEATKHLE +KQLAAAF EEF VREDLMGLAIGTHG+NIQQ
Sbjct: 184 LSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQ 243
Query: 254 ARKVPGVTAIELGEETCTFRIYGETPEACRQARSYLEFSEDSVQVPRNLVGKVIGKNGKV 313
ARKVPGVTAIEL E+T TFRIYGE+ +A ++AR +LEF ED +QVPRNLVGKVIGKNGKV
Sbjct: 244 ARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKV 303
Query: 314 IQEIVDKSGVVRVRVEGDNDKKNPREEGMVPFIFVGTRENISNAQALLEYHLSYLQEVEQ 373
IQEIVDKSGVVRVR+EGDN+ K PRE+GMVPF+FVGT+E+I N Q LLEYH++YL+EVEQ
Sbjct: 304 IQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQ 363
Query: 374 LRLERLQIDEQLRQIGLGFRPPGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRG 433
LR+ERLQIDEQLRQIG SY GRG
Sbjct: 364 LRMERLQIDEQLRQIG------------------------------------SRSYSGRG 387
Query: 434 RGRRTGGP----AYGPSSDVSTASETESEKREEP---NRAGPGDRDPPTRGEESRRRP-- 484
RGRR GP YG +S++S SETESE+++E + AG DRD +SRRRP
Sbjct: 388 RGRR--GPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRD-SRHQRDSRRRPGG 444
Query: 485 -----TGGRGRGPPPAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPP 539
+GGRGRG P R SSISSVLKDPDSNPYSLLD +E + D++ E
Sbjct: 445 RGRSVSGGRGRGGP-------RGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESH 497
Query: 540 PASARRRRSRRRRTDEDRTVMDGGLESDGPNMTENGL 576
++ RRRRSRRRRTDED +MDG ESD ++ ENGL
Sbjct: 498 HSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGL 534
>gi|61835172 fragile X mental retardation-related protein 1 isoform
c [Homo sapiens]
Length = 536
Score = 586 bits (1510), Expect = e-167
Identities = 342/614 (55%), Positives = 403/614 (65%), Gaps = 114/614 (18%)
Query: 96 MMKGDFYVIEYAACDATYNEIVTLERLRPVNPNPLATKGSFFKVTMAVPEDLREACSNEN 155
MMKG+FYVIEYAACDATYNEIVT ERLRPVN N K +FFK T+ VPEDLREAC+NEN
Sbjct: 1 MMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANEN 60
Query: 156 VHKEFKKALGANCIFLNITNSELFILSTTEAPVKRASLLGDMHFRSLRTKLLLMSRNEEA 215
HK+FKKA+GA IF + ++L ILS +EA VKR ++L DMH RS+RTKL+LMSRNEEA
Sbjct: 61 AHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEA 120
Query: 216 TKHLETSKQLAAAFQEEFTVREDLMGLAIGTHGANIQQARKVPGVTAIELGEETCTFRIY 275
TKHLE +KQLAAAF EEF VREDLMGLAIGTHG+NIQQARKVPGVTAIEL E+T TFRIY
Sbjct: 121 TKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIY 180
Query: 276 GETPEACRQARSYLEFSEDSVQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRVEGDNDKK 335
GE+ +A ++AR +LEF ED +QVPRNLVGKVIGKNGKVIQEIVDKSGVVRVR+EGDN+ K
Sbjct: 181 GESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENK 240
Query: 336 NPREEGMVPFIFVGTRENISNAQALLEYHLSYLQEVEQLRLERLQIDEQLRQIGLGFRPP 395
PRE+GMVPF+FVGT+E+I N Q LLEYH++YL+EVEQLR+ERLQIDEQLRQIG
Sbjct: 241 LPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIG------ 294
Query: 396 GSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGP----AYGPSSDVST 451
SY GRGRGRR GP YG +S++S
Sbjct: 295 ------------------------------SRSYSGRGRGRR--GPNYTSGYGTNSELSN 322
Query: 452 ASETESEKREEP---NRAGPGDRDPPTRGEESRRRP-------TGGRGRGPPPAPRPTSR 501
SETESE+++E + AG DRD +SRRRP +GGRGRG P R
Sbjct: 323 PSETESERKDELSDWSLAGEDDRD-SRHQRDSRRRPGGRGRSVSGGRGRGGP-------R 374
Query: 502 YNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMD 561
SSISSVLKDPDSNPYSLLD +E + D++ E ++ RRRRSRRRRTDED +MD
Sbjct: 375 GGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMD 434
Query: 562 GGLESDGPNMTENGLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRAESQ 621
G ESD ++ ENGL VTVADYISRAESQ
Sbjct: 435 GMTESDTASVNENGL--------------------------------VTVADYISRAESQ 462
Query: 622 SRQ----------------SAPLERTKPSEDSLSG---QKGDSVSKLPKGPSE---NGEL 659
SRQ +E PSE +++G GD +SKL + P E N
Sbjct: 463 SRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLK 522
Query: 660 SAPLELGSMVNGVS 673
+ +++NGVS
Sbjct: 523 EENTQEAAVLNGVS 536
>gi|4503765 fragile X mental retardation 1 [Homo sapiens]
Length = 632
Score = 485 bits (1249), Expect = e-137
Identities = 237/331 (71%), Positives = 278/331 (83%)
Query: 14 LPVEVRGSNGAFYKGFVKDVHEDSVTIFFENNWQSERQIPFGDVRLPPPADYNKEITEGD 73
L VEVRGSNGAFYK FVKDVHEDS+T+ FENNWQ +RQIPF DVR PPP YNK+I E D
Sbjct: 4 LVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDINESD 63
Query: 74 EVEVYSRANEQEPCGWWLARVRMMKGDFYVIEYAACDATYNEIVTLERLRPVNPNPLATK 133
EVEVYSRANE+EPC WWLA+VRM+KG+FYVIEYAACDATYNEIVT+ERLR VNPN ATK
Sbjct: 64 EVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATK 123
Query: 134 GSFFKVTMAVPEDLREACSNENVHKEFKKALGANCIFLNITNSELFILSTTEAPVKRASL 193
+F K+ + VPEDLR+ C+ E HK+FKKA+GA + + N +L ILS E KRA +
Sbjct: 124 DTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKRAHM 183
Query: 194 LGDMHFRSLRTKLLLMSRNEEATKHLETSKQLAAAFQEEFTVREDLMGLAIGTHGANIQQ 253
L DMHFRSLRTKL L+ RNEEA+K LE+S+QLA+ F E+F VREDLMGLAIGTHGANIQQ
Sbjct: 184 LIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQ 243
Query: 254 ARKVPGVTAIELGEETCTFRIYGETPEACRQARSYLEFSEDSVQVPRNLVGKVIGKNGKV 313
ARKVPGVTAI+L E+TCTF IYGE +A ++ARS+LEF+ED +QVPRNLVGKVIGKNGK+
Sbjct: 244 ARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKL 303
Query: 314 IQEIVDKSGVVRVRVEGDNDKKNPREEGMVP 344
IQEIVDKSGVVRVR+E +N+K P+EE ++P
Sbjct: 304 IQEIVDKSGVVRVRIEAENEKNVPQEEEIMP 334
Score = 129 bits (324), Expect = 9e-30
Identities = 99/307 (32%), Positives = 149/307 (48%), Gaps = 51/307 (16%)
Query: 208 LMSRNEEATKHLETSKQLAAAFQEEFTVREDLMGLAIGTHGANIQQARKVPGVTAIELGE 267
+ +++A K + + A ++ V +L+G IG +G IQ+ GV + +
Sbjct: 264 IYGEDQDAVKKARSFLEFA---EDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEA 320
Query: 268 E------------------TCTFRIYGETPEACRQARSYLEFSEDSVQVPRNLVGKVIGK 309
E + R+ PE + +L+ E+S +
Sbjct: 321 ENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEE----KKHLDIKENSTHFSQ--------P 368
Query: 310 NGKVIQEIVDKSGVVRVRVEGDNDKKNPRE-EGMVPFIFVGTRENISNAQALLEYHLSYL 368
N +Q ++ S VV G++ K + +GMVPF+FVGT+++I+NA LL+YHL+YL
Sbjct: 369 NSTKVQRVLVASSVVA----GESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYHLNYL 424
Query: 369 QEVEQLRLERLQIDEQLRQIGLGFRPPGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGS 428
+EV+QLRLERLQIDEQLRQIG RPP + + Y TD+ +
Sbjct: 425 KEVDQLRLERLQIDEQLRQIGASSRPPPNRT----DKEKSYVTDDGQGMGRGSR-----P 475
Query: 429 YGGRGRGRRTGGPAYGPSSDVSTASETESEKREEPN----RAGPGDRDPPTRGEESRRRP 484
Y RG GRR G G +S+ S ASETES+ R+E + +R+ R + RRR
Sbjct: 476 YRNRGHGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRG 535
Query: 485 TGGRGRG 491
GGRG+G
Sbjct: 536 GGGRGQG 542
>gi|50083281 KIAA1853 protein [Homo sapiens]
Length = 611
Score = 53.1 bits (126), Expect = 8e-07
Identities = 73/246 (29%), Positives = 95/246 (38%), Gaps = 42/246 (17%)
Query: 414 SSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRDP 473
S SSS +TR+ S+ R R P Y S ST+SE S R + G R P
Sbjct: 390 SRSSSYASTRS--SSHSSRSPNPRAS-PRYTQSR--STSSEKRSYSRSPSYSSKSGKRSP 444
Query: 474 PTRGEESRRRPTGGRGRGPPPAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPE----- 528
P+R SRR P+ SRY+ S +DP YS D+ + E
Sbjct: 445 PSRSSRSRRSPS-------------YSRYSPSR----ERDP---KYSEKDSQQRERERAR 484
Query: 529 -------PPVDSEPGEPPPASARRRRSRRRRT---DEDRTVMDGGLESDGPNMTENGLED 578
P P ARR S R+R G L S + +
Sbjct: 485 RRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRS 544
Query: 579 ESRPQRRNRSRRRRNRGNRT-DGSISGDRQPVTVADYISRAESQSR-QSAPLERTKPSED 636
SR R+RSR R R +RT S S R P + SR+ S+SR +S R+ S D
Sbjct: 545 ASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSAD 604
Query: 637 SLSGQK 642
S S +
Sbjct: 605 SYSSTR 610
Score = 30.0 bits (66), Expect = 7.3
Identities = 25/91 (27%), Positives = 35/91 (38%), Gaps = 6/91 (6%)
Query: 392 FRPPGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTG------GPAYGP 445
+RP S GS S + YS+ S S+S +R+ S R RT P+ G
Sbjct: 520 YRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGS 579
Query: 446 SSDVSTASETESEKREEPNRAGPGDRDPPTR 476
S + S + S R + D TR
Sbjct: 580 RSRSRSRSRSRSRSRSQSRSYSSADSYSSTR 610
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 52.0 bits (123), Expect = 2e-06
Identities = 66/269 (24%), Positives = 97/269 (36%), Gaps = 19/269 (7%)
Query: 393 RPPGSGRGSGGSDKAGYSTDESSSS---SLHATRTYGGSYGGRGRG-RRTGGPAYGPSSD 448
R PGS S + + S S S+ S R GGS R R RR + P
Sbjct: 560 RKPGS-HASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPA 618
Query: 449 VSTASETESEKREEPNRAGPGDRDPPTRGEESRRRPTG-GRGRGPPPAPRPT-------- 499
S++S + E+ +R G G + R + +G G + P PAP P+
Sbjct: 619 TSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDR 678
Query: 500 -SRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRT 558
SR + S+ D + +++ T S+P P PA A + E +
Sbjct: 679 DSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPASSPKREVLYDSEGLS 738
Query: 559 VMDGGLESDGPNMTENGLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRA 618
+ G +S + +G S R SRR+ G D DR D S+
Sbjct: 739 GEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRD----RDRSSKK 794
Query: 619 ESQSRQSAPLERTKPSEDSLSGQKGDSVS 647
++SAP P SG S S
Sbjct: 795 ARPPKESAPSSGPPPKPPVSSGSGSSSSS 823
Score = 39.7 bits (91), Expect = 0.009
Identities = 53/230 (23%), Positives = 75/230 (32%), Gaps = 56/230 (24%)
Query: 436 RRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRDPPTRGEESRRRPTGGRGRGPPPA 495
+R+ PA P+ + T + R E R+G E++ + G P P
Sbjct: 496 QRSPSPAPAPAPAAAAGPPTRKKSRRERKRSG-----------EAKEAASSSSGTQPAP- 543
Query: 496 PRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDE 555
P P S ++S S D +PG +SARRR R R+
Sbjct: 544 PAPASPWDSKKHRS---------------------RDRKPGSHASSSARRRSRSRSRSRS 582
Query: 556 DRTVMDGGLESDGPNMTENGLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYI 615
R S +RR SRR R+R R S P T +
Sbjct: 583 TRR------------------RSRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSSSS 624
Query: 616 SRAESQSRQ----SAPLERTKPSEDSLSGQKGDSVSKLP-KGPSENGELS 660
SR E + ++ K S + GD K P P +G S
Sbjct: 625 SRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTS 674
Score = 35.8 bits (81), Expect = 0.13
Identities = 44/167 (26%), Positives = 55/167 (32%), Gaps = 18/167 (10%)
Query: 485 TGGRGRGPPPAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVD--------SEPG 536
TG G PPPAP S S S SS P P + P P D E
Sbjct: 179 TGDGGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAY 238
Query: 537 EPPPASARRR---RSRRRRTDEDRTVMDGGLESDGPNMTENGLEDESRPQRRNRSRRRRN 593
PPPA ++ E + E EDE + ++S R +
Sbjct: 239 SPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRIS 298
Query: 594 R---GNRTDGSISGDRQPVTVADYISRAESQSRQSAPLERTKPSEDS 637
G D S+S D D R ++Q Q P T P DS
Sbjct: 299 ETLAGIYDDNSLSQD----FPGDESPRPDAQPTQPTPAPGTPPQVDS 341
Score = 34.7 bits (78), Expect = 0.29
Identities = 26/86 (30%), Positives = 36/86 (41%), Gaps = 2/86 (2%)
Query: 426 GGSYGGRG--RGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRDPPTRGEESRRR 483
G GG+ + RR G A SS S ++ + +R DRD +++R
Sbjct: 739 GEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPP 798
Query: 484 PTGGRGRGPPPAPRPTSRYNSSSISS 509
GPPP P +S SSS SS
Sbjct: 799 KESAPSSGPPPKPPVSSGSGSSSSSS 824
Score = 30.4 bits (67), Expect = 5.6
Identities = 48/227 (21%), Positives = 71/227 (31%), Gaps = 32/227 (14%)
Query: 437 RTGGPAYGPSSDVSTASETESEKREEPNRAGPGDR----DPPTRGEESRRRPTGGRGRGP 492
R GG A P+ S + + RA GD + GE + + G P
Sbjct: 411 RPGGRAARPTPAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAP 470
Query: 493 PPAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRR 552
P A SR+ + + Y S P + PP RR +R
Sbjct: 471 PAA---DSRWGGLDLRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSG 527
Query: 553 TDEDRTVMDGGLESDGP-------------NMTENGLEDESRPQRRNRSRRR----RNRG 595
++ G + P + G S +RR+RSR R R R
Sbjct: 528 EAKEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRS 587
Query: 596 NRTDGSISGDRQPVTVADYISRAESQSRQSAPLERTKPSEDSLSGQK 642
TD G R+ SR+ + R+ P+ S S +
Sbjct: 588 RSTDRRRGGSRR--------SRSREKRRRRRRSASPPPATSSSSSSR 626
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 50.8 bits (120), Expect = 4e-06
Identities = 59/233 (25%), Positives = 87/233 (37%), Gaps = 46/233 (19%)
Query: 389 GLGFRPPGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSD 448
G GFR GRG G + R+Y G GRG TGGP + P+
Sbjct: 1035 GRGFRGTYGGRGRGARSRE--------------FRSYREFRGDDGRGGGTGGPNHPPAPR 1080
Query: 449 VSTASETESE----------KREEPNRAG---------PGDRDPPTRGEESRRR-PTGGR 488
TASET SE +R+ + G P D++ PT E + + P
Sbjct: 1081 GRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPP 1140
Query: 489 GRGPPPAPRP---TSR----YNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPP-- 539
G PP+P P T+R + + S P + P P +PP
Sbjct: 1141 PPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTG 1200
Query: 540 PASARRRRSRRRRTDEDRTVMDGGLESDGPNMTENGLEDESRPQRRNRSRRRR 592
P + + + + + G + G N+ G+ED RP+RR R ++
Sbjct: 1201 PLPPSKEPLKEKLIPGPLSPVARGGSNGGSNV---GMEDGERPRRRRHGRAQQ 1250
Score = 34.7 bits (78), Expect = 0.29
Identities = 49/198 (24%), Positives = 74/198 (37%), Gaps = 30/198 (15%)
Query: 396 GSGRGSGGSDKAGYST----DESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVST 451
G+ G GG G S D S + + R++ G R R GP S S+
Sbjct: 1352 GTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSS 1411
Query: 452 ASETESEKREEPNRAGPGDRDPPTRGE-------ESRRRPTGGRGRG---PPPAPRPTSR 501
+ GPG R P RG+ ++R RP R G PPP P ++
Sbjct: 1412 SGG---------GGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAV 1462
Query: 502 YNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPG----EPPPASARRRRSRRRRTDEDR 557
+ + + +P +L S + V + G +P A + S R T +
Sbjct: 1463 FRLDQV--IHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQGPSPRPPTRYEP 1520
Query: 558 TVMDGGLESDGPNMTENG 575
++ GL SD P+ E G
Sbjct: 1521 QRVNSGLSSD-PHFEEPG 1537
Score = 31.2 bits (69), Expect = 3.3
Identities = 28/104 (26%), Positives = 38/104 (36%), Gaps = 11/104 (10%)
Query: 445 PSSDVSTASETESEKREEPNRAGPGDRDPPTRGEESRRRPTGGRGRGPPPAPRPTSRY-- 502
P SD +T K+E P P + +R +GG+G PP PR SR
Sbjct: 868 PGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQG---PPPPRRESRTET 924
Query: 503 ------NSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPP 540
SS ++P + P +P PP E P P
Sbjct: 925 RWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKP 968
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 50.1 bits (118), Expect = 7e-06
Identities = 70/273 (25%), Positives = 92/273 (33%), Gaps = 42/273 (15%)
Query: 394 PPGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTAS 453
PP S GS S + + S R S R R + SS T S
Sbjct: 1662 PPKSRTARRGSRS---SPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRS 1718
Query: 454 ETESEKREEPNRAGPGDRDPPTRGEESRRR---------PTGGRGRGPPPAPRPTSRYNS 504
T R P+ + P +P + SRRR T RGR P P PR R S
Sbjct: 1719 RTPPRHRRSPSVSSP---EPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRS 1775
Query: 505 SSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGL 564
S + S G S RR+RSR R R G
Sbjct: 1776 RSRREKTRTTRRRDRS---------------GSSQSTSRRRQRSRSRSRVTRRRRGGSGY 1820
Query: 565 ESDGPNMTENGLEDESR--------PQRRNRSRRRRN----RGNRTDGSISGDRQPVTVA 612
S P E+ R P R RSR R + + +R+ S + R+ +
Sbjct: 1821 HSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRT 1880
Query: 613 DYISRAESQSRQSAPLERTKPSEDSLSGQKGDS 645
ISR S+SR S R S S++ ++ S
Sbjct: 1881 PLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRS 1913
Score = 45.4 bits (106), Expect = 2e-04
Identities = 57/220 (25%), Positives = 83/220 (37%), Gaps = 31/220 (14%)
Query: 393 RPPGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTA 452
+P + R GSD S+ E + + A S G +GR GPS + S++
Sbjct: 1607 KPRAAPRAQSGSD----SSPEPKAPAPRALPRRSRS-GSSSKGR-------GPSPEGSSS 1654
Query: 453 SETESEKREEPNRAGPGDRDPPTRGEESRRRPTGGRGRGPPPAPRPT-----SRYNSSSI 507
+E+ E + A G R P +SR P R P R SR SSS
Sbjct: 1655 TESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSP 1714
Query: 508 SSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGLESD 567
+ + P + S S PEP + + R SRRRR+
Sbjct: 1715 ETRSRTPPRHRRSP-SVSSPEP------------AEKSRSSRRRRSASSPRTKTTSRRGR 1761
Query: 568 GPNMTENGLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQ 607
P+ GL+ RR ++R R R +R+ S S R+
Sbjct: 1762 SPSPKPRGLQRSRSRSRREKTRTTRRR-DRSGSSQSTSRR 1800
Score = 43.9 bits (102), Expect = 5e-04
Identities = 53/219 (24%), Positives = 80/219 (36%), Gaps = 32/219 (14%)
Query: 395 PGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASE 454
P R S S + S+ SSSSS ++ + G S S + E
Sbjct: 2526 PAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD------------SEGSSLPVQPE 2573
Query: 455 TESEKREEPNRA---GPGDRDPPTRGEESRRRPTGGRGRGPPPAPRPTSRYNSSSISSVL 511
++ P A + PP R+R + + +S +SSS SS
Sbjct: 2574 VALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSS 2633
Query: 512 KDPDSNPYSLLDTSEPEP--------PVDSEPGEPPPASARRRRSRRRRTD---EDRTVM 560
S+ S +S P P P + P +PPP RR RS R+ D + R++
Sbjct: 2634 SSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGE-RRSRSPRKPIDSLRDSRSLS 2692
Query: 561 DGGLESDGPNMTENGLEDESRPQRRNRSRRRRNRGNRTD 599
+E P+ + R Q+ + S R RG R D
Sbjct: 2693 YSPVERRRPSP-----QPSPRDQQSSSSERGSRRGQRGD 2726
Score = 41.6 bits (96), Expect = 0.002
Identities = 64/281 (22%), Positives = 102/281 (36%), Gaps = 37/281 (13%)
Query: 401 SGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETESEKR 460
S S S S+++ H T G S GRR G A P S+ T S
Sbjct: 268 SASSSDTSRSRSRSAAAKTHTTALAGRS-PSPASGRRGEGDA--PFSEPGTTSTQRPSSP 324
Query: 461 EEPNR--AGPGDRDPPTRGEESRRRPTGGRGR---GP-PPAPRP--TSRYNSS----SIS 508
E + + P + + E+S RP+ R GP PPAP P R+ S + +
Sbjct: 325 ETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATT 384
Query: 509 SVLKDPDSNPYSLLDTSEPEPP-----------VDSEPGEPPPASARRRRSRRRRTDEDR 557
+ ++P + P T + PP +S P P P R S + +
Sbjct: 385 PLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPA 444
Query: 558 TVMDGGLE-SDGPNMTENGLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYIS 616
E S P S+ + R++R ++ + + R P T S
Sbjct: 445 PAPGSHREISSSPT---------SKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRS 495
Query: 617 RAESQSRQSAPLERTKPSEDSLSGQK-GDSVSKLPKGPSEN 656
R+ + +++ R+ S S Q+ G S S +G S +
Sbjct: 496 RSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRS 536
Score = 40.4 bits (93), Expect = 0.005
Identities = 54/230 (23%), Positives = 77/230 (33%), Gaps = 22/230 (9%)
Query: 410 STDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVS-------TASETESEKREE 462
S +SS S TRT R R R P S +S ++ E + + R
Sbjct: 1557 SESDSSPDSKAKTRT-----PLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAA 1611
Query: 463 PNRAGPGDRDPPTRGEESRRRPTGGRGRGPPPAPRPTSRYNSSSISSVLKDPDSNPYSLL 522
P D P + R P R P+ +SS+ SS P S
Sbjct: 1612 PRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRG 1671
Query: 523 DTSEPEPPVDSEPGEPPPASARR------RRSRRRRTDEDRTVMDGGLESDGPNMTENGL 576
S PEP S PP + R R++R R + P +
Sbjct: 1672 SRSSPEPKTKSR--TPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPS 1729
Query: 577 EDESRPQRRNRSRRRRNRGN--RTDGSISGDRQPVTVADYISRAESQSRQ 624
P ++RS RRR + RT + R P + R+ S+SR+
Sbjct: 1730 VSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRR 1779
Score = 39.3 bits (90), Expect = 0.012
Identities = 57/246 (23%), Positives = 87/246 (35%), Gaps = 21/246 (8%)
Query: 399 RGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETESE 458
R S +++ + + + L A R +GGS + P PS T + +
Sbjct: 349 RPSPSPERSSTGPEPPAPTPLLAER-HGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPK 407
Query: 459 KREEPNRAGPGDRDPPTRGEESRRRPTGGRGRGPPPAPRPTSRYNSSSISSVLKDPDSNP 518
E+ ++ + PP+ R P PAP P S S SS S+
Sbjct: 408 SPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREIS--SSPTSKNRSHG 465
Query: 519 YSLLDTSEPEPPVDSEPGEPPPASARRRRSRRR--------RTDEDRTVMDGGLESDGPN 570
+ D S P PA+A+R RSR R R+ + + G +
Sbjct: 466 RAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRS 525
Query: 571 MTENGLEDESRPQR----RNRSRRRRNRGNRTDGSISGDRQPVTVADYISRAESQSRQSA 626
+ PQR R+R+ +RR R S R P T R S+SR A
Sbjct: 526 RSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPAT------RGRSRSRTPA 579
Query: 627 PLERTK 632
R++
Sbjct: 580 RRGRSR 585
Score = 38.1 bits (87), Expect = 0.027
Identities = 60/242 (24%), Positives = 77/242 (31%), Gaps = 19/242 (7%)
Query: 431 GRGRGRRTG-----GPAYGPSSDVSTASETESEKREEPNRAGPGDRDPPTRGEESRRRPT 485
GR R R G PA S T + + P R R P R SR
Sbjct: 552 GRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPAR 611
Query: 486 GGRGRGPPPAPRPTS-----RYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPG---- 536
GR R PA R + R S S S + S + + G
Sbjct: 612 RGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRS 671
Query: 537 EPPPASARRRRSR---RRRTDEDRTVMDGGLESDGPNMTENGLEDESRPQRRNRSRRRRN 593
P + R RSR RR RT G S ++ G PQRR RS
Sbjct: 672 RTPARRSGRSRSRTPARRGRSRSRTPRRG--RSRSRSLVRRGRSHSRTPQRRGRSGSSSE 729
Query: 594 RGNRTDGSISGDRQPVTVADYISRAESQSRQSAPLERTKPSEDSLSGQKGDSVSKLPKGP 653
R N++ S R + SR S+ +S R+K + S PK
Sbjct: 730 RKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQK 789
Query: 654 SE 655
S+
Sbjct: 790 SQ 791
Score = 37.0 bits (84), Expect = 0.059
Identities = 58/218 (26%), Positives = 79/218 (36%), Gaps = 39/218 (17%)
Query: 447 SDVSTASETESEKREEP-NRAGPGDRDPPTRGEESRRRPTGGRGRG---PPPAPRPTSRY 502
S S S S R P R R P TR R P R R PP R SR
Sbjct: 1913 SRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRS 1972
Query: 503 NSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRR------RRTDED 556
+S I+ ++P + + PV + RRRSR RR
Sbjct: 1973 RTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRS 2032
Query: 557 RTVMDGGLESDGPNMTENGLEDESRPQRRNRSR-----RRRNRGNRTDGSISGDRQPVTV 611
RT + P++R+RSR RRR+R +RT + G R +T
Sbjct: 2033 RTPL--------------------LPRKRSRSRSPLAIRRRSR-SRTPRTARGKRS-LTR 2070
Query: 612 ADYISRAESQSRQSAPLER--TKPSEDSLSGQKGDSVS 647
+ R S S S+ R T P+ + SG + V+
Sbjct: 2071 SPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVA 2108
Score = 33.9 bits (76), Expect = 0.50
Identities = 59/270 (21%), Positives = 89/270 (32%), Gaps = 31/270 (11%)
Query: 409 YSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTA-----SETESEKREEP 463
YS SSSS T + RGRR+ + S+ SE+ES+KR+
Sbjct: 171 YSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKH- 229
Query: 464 NRAGPGDRDPPTRGEESRRRPTGGRGRGPPPAPRPTSRYNSSSISSVLKDPDSNPYSLLD 523
R P + + + R R PAP+ + S+S S S S
Sbjct: 230 -------RSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSA 282
Query: 524 TSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGLESDGPNMTENGLEDESRPQ 583
++ P PAS RR ++ G + P+ E + S P
Sbjct: 283 AAKTHTTA-LAGRSPSPASGRRGEGDAPFSE------PGTTSTQRPSSPETATKQPSSPY 335
Query: 584 RRNRSRRRRNRGNR----TDGSISGDRQPVTVADYISR--AESQSRQSAPLER---TKPS 634
++ R + S +G P R Q + PL + PS
Sbjct: 336 EDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPS 395
Query: 635 EDSLSGQKG--DSVSKLPKGPSENGELSAP 662
E S + + S KLP+ S +P
Sbjct: 396 EASPTRDRSPPKSPEKLPQSSSSESSPPSP 425
Score = 33.5 bits (75), Expect = 0.66
Identities = 55/236 (23%), Positives = 82/236 (34%), Gaps = 27/236 (11%)
Query: 444 GPSSDVSTASETESEKREEPNRAGPGDRDPPTRGEESRRRPTGGRGRGPPPAPRP----T 499
G SS+ S +S P+R P + R P+ G P R
Sbjct: 1395 GMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTP 1454
Query: 500 SRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPAS--------------ARR 545
SR++ S S +KD P + P + P P P S +R
Sbjct: 1455 SRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQR 1514
Query: 546 RRSRRRRTDEDRTVMDG--GLESDGPNMTENGLEDESRPQRRNRS-----RRRRNRGNRT 598
RS + + +TV G S + E ++ + PQ R+ S + + R
Sbjct: 1515 ERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLR 1574
Query: 599 DGSISGDRQPVTVADYISRAESQSRQSAPLERTKPSEDSLSGQKGDSVSKLPKGPS 654
S SG V +S S+S S+P + KP + Q G S PK P+
Sbjct: 1575 QRSRSGSSPEVDSKSRLSPRRSRS-GSSPEVKDKP-RAAPRAQSGSDSSPEPKAPA 1628
Score = 31.6 bits (70), Expect = 2.5
Identities = 65/287 (22%), Positives = 95/287 (33%), Gaps = 32/287 (11%)
Query: 399 RGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETESE 458
RG S S + + +R+ + GR R R S V S + S
Sbjct: 581 RGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSP 640
Query: 459 KREEPNRAGPGDRDPPTRGEESRRRPTGGRGRGPPPAPRPTSRYNSS--------SISSV 510
R R+G P R SR R RGR P S + S S S
Sbjct: 641 AR----RSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRT 696
Query: 511 LKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGLESDGPN 570
+ S SL+ G +S R+ +S RT + R+ + E
Sbjct: 697 PRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKS---RTSQRRSRSNSSPEMKKSR 753
Query: 571 MTENGLEDESRPQRRNRSR---RRRNRGNR----------TDGSISGDRQPVTVADYISR 617
++ S P+ + +SR RR G+ S SG QP + R
Sbjct: 754 ISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR 813
Query: 618 AESQSRQSAPLERTK-PSEDSLSGQKGDSVSKLPKG-PSENGELSAP 662
S P +++K PS S S K+ G P G +++P
Sbjct: 814 RSRSSSSPPPKQKSKTPSRQSHSSSSPH--PKVKSGTPPRQGSITSP 858
Score = 31.6 bits (70), Expect = 2.5
Identities = 47/229 (20%), Positives = 73/229 (31%), Gaps = 46/229 (20%)
Query: 446 SSDVSTASETESEKREEPNRAGPGDRDP-----PTRGEESRRR-------PTGGRGRGPP 493
SS S++S + S + +G D P + E + +R P G P
Sbjct: 2536 SSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRP 2595
Query: 494 PAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRT 553
P P P R SS SS S+ S +S S +S+ S +
Sbjct: 2596 PEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAK-- 2653
Query: 554 DEDRTVMDGGLESDGPNMTENGLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVAD 613
GP + P RSR R+P+
Sbjct: 2654 -------------PGPQALPKPASPKKPPPGERRSR--------------SPRKPID--- 2683
Query: 614 YISRAESQSRQSAPLERTKPSEDSLSGQKGDSVSKLPKGPSENGELSAP 662
S +S+S +P+ER +PS + S S+ + G+ +P
Sbjct: 2684 --SLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSP 2730
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 48.9 bits (115), Expect = 2e-05
Identities = 66/289 (22%), Positives = 107/289 (37%), Gaps = 38/289 (13%)
Query: 386 RQIGLGFRPPGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGP 445
+++G+ P + R S + +++ S SSS + +Y GS R R R + +Y
Sbjct: 527 KKLGVSVSPSRARRRRKTSASSASASNSSRSSS--RSSSYSGSGSSRSRSRSSSYSSYSS 584
Query: 446 -SSDVSTASETESEKREEPNRAGPGDRDPP------TRGEESRRRPTGGRGRGPPPAPRP 498
SS S+ S + S R + P P T+GE + G PAP P
Sbjct: 585 RSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPP 644
Query: 499 TSRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRT 558
+ + + V PEP ++PG+P A RR+ R RT R
Sbjct: 645 APPQATKTTAPV----------------PEP---TKPGDPREA---RRKERPARTPPRRR 682
Query: 559 VMDGGLESDGPNMTENGLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRA 618
+ G G + + + S S + + S+ + +A +S A
Sbjct: 683 TLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSA 742
Query: 619 ESQSRQSAPLERTKPSEDSLSG-----QKGDSVSKLPKG--PSENGELS 660
S+S A + K G +K DS ++ PK P G+ S
Sbjct: 743 SSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSS 791
Score = 42.7 bits (99), Expect = 0.001
Identities = 59/272 (21%), Positives = 97/272 (35%), Gaps = 36/272 (13%)
Query: 396 GSGRGSGGSDKAGYSTDES---SSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTA 452
GSG GSG S S S SS S ++ T S P S S+
Sbjct: 686 GSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSR 745
Query: 453 SETESEKREEPNRAGPGD--------RDPPTRGEESRRRPTGGRG--------RGPPPAP 496
S ++ R+E ++ D RD T+ +S + P GG+ + PP P
Sbjct: 746 SPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQP 805
Query: 497 RPTSRYNSSSISSVLKDPDSNP-----YSLLDTSEPEPPVDSEPGEPPPASARRRRSRRR 551
+ + I L + ++ Y D PP P P +R R+S
Sbjct: 806 QQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKS-GG 864
Query: 552 RTDEDRTVMDGGLESDGPNMTENGLEDESRPQRRNRSRRRRNRGNRTDGSISGD-RQPVT 610
R + G S P + P R R +++ + S+ G P
Sbjct: 865 RLGSPKPERQRGQNSKAP----------AAPADRKRQLSPQSKSSSKVTSVPGKASDPGA 914
Query: 611 VADYISRAESQSRQSAPLERTKPSEDSLSGQK 642
+ +A + SR+ L++ K ED+++ ++
Sbjct: 915 ASTKSGKASTLSRREELLKQLKAVEDAIARKR 946
Score = 30.8 bits (68), Expect = 4.3
Identities = 19/86 (22%), Positives = 33/86 (38%)
Query: 573 ENGLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRAESQSRQSAPLERTK 632
EN + R + R+R R RR R + D++ + R ++ + R +
Sbjct: 411 ENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDR 470
Query: 633 PSEDSLSGQKGDSVSKLPKGPSENGE 658
E +KG + P+ PS E
Sbjct: 471 DREKEREKEKGKPKPRSPQPPSRQAE 496
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 48.5 bits (114), Expect = 2e-05
Identities = 64/309 (20%), Positives = 112/309 (36%), Gaps = 19/309 (6%)
Query: 362 EYHLSYLQEVEQLRLERLQIDEQLRQIGL------GFRPPGSGRGSGGSDKAGYSTDESS 415
E L +E ++L +R Q E+ + I + + G G G K G DE
Sbjct: 862 EKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFV 921
Query: 416 SSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRDPPT 475
+ + + RR G + D + ++R P D D
Sbjct: 922 NDDTDDDLPIS-----KKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETE 976
Query: 476 RGEESRRR--PTGGRGRGPPPAPRPTSRYNSSSISSVLKDPD-SNPYSLLDTSEPEPPVD 532
G + ++R P + + P P P S +++ D S+ L ++ P +
Sbjct: 977 NGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRN 1036
Query: 533 SEPGEPPPASARRRRSRRRRTDEDRTVMDGGLESDGPNMTENGLEDESRPQRRNRSRRRR 592
S +R++ +D D G E+ P D+ + +RR
Sbjct: 1037 SNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRP 1096
Query: 593 NRGNRTDG-SISGDRQPVTVADYISRAESQSRQSAPLERTKPSEDSLSGQKGDSVSKLPK 651
+ ++D S+ R V++ SR S S +S E + S++ SGQ + S+ P+
Sbjct: 1097 SGSEQSDNESVQSGRSHSGVSENDSRPASPSAES-DHESERGSDNEGSGQGSGNESE-PE 1154
Query: 652 GPSENGELS 660
G N E S
Sbjct: 1155 G--SNNEAS 1161
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 48.5 bits (114), Expect = 2e-05
Identities = 51/207 (24%), Positives = 80/207 (38%), Gaps = 23/207 (11%)
Query: 441 PAYGPSSDVSTAS-----ETESEKREEPNRAGPGDRDPPTRGEESRRRPTGGRGRGPPPA 495
P PS +TAS + E +E P+ AGP D+ R + + P PA
Sbjct: 491 PPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPA 550
Query: 496 PRPTSRYNSSSISSVLKDPDSNPY-SLLDTSEPEPPVDSEPGEPPPASARR--------R 546
P PT + P P + + TS P P P +P + R
Sbjct: 551 PSPTPAPPQKE-----QPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAE 605
Query: 547 RSRRRRTDEDRTVMDGGLESD-GPNMTENGL--EDESRPQRRNRSRRRRNRGNRTDGSIS 603
+ R+ R +R + L+++ M E L E E+R +R +RRR + R
Sbjct: 606 KRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAE 665
Query: 604 GDRQPVTVADYISRAESQSRQSAPLER 630
+ Q + AE++SR+ A +R
Sbjct: 666 QEEQE-RLQKQKEEAEARSREEAERQR 691
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 48.1 bits (113), Expect = 3e-05
Identities = 60/267 (22%), Positives = 87/267 (32%), Gaps = 26/267 (9%)
Query: 393 RPPGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTA 452
R S +G GG G +R+ + RGR R P G S +S A
Sbjct: 367 RSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRA 426
Query: 453 SETESEKREEPNRAGPG-----DRDPPTRGEESRRRPTGGRGRGPPPAPRPTSRYNSSSI 507
+ S+ GPG +R G+ ++ RP R P+P R
Sbjct: 427 -RSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEG 485
Query: 508 SSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGLESD 567
S + P +P S + P S E P S R S ++ D+ D
Sbjct: 486 KSSSRSPGPHPRSWSSSRSPSKS-RSRSAEKRPHSPSRSPSPKKPLSRDK---------D 535
Query: 568 GPNMTENGLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRAESQSRQSAP 627
G + + +R +RR+RS + R S R R S ++ P
Sbjct: 536 GEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPR----------RITSARKRPIP 585
Query: 628 LERTKPSEDSLSGQKGDSVSKLPKGPS 654
R PS S S + PS
Sbjct: 586 YYRPSPSSSSSCLSSDYSTRSHSRSPS 612
Score = 47.0 bits (110), Expect = 6e-05
Identities = 67/268 (25%), Positives = 87/268 (32%), Gaps = 35/268 (13%)
Query: 408 GYSTDESSSSSLHATRTYGGSYGGR-----GRGRRTGGPAYGPSSDVSTASETESEKREE 462
G T SS + GGS G G G+R+G P S S + S
Sbjct: 286 GRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRV 345
Query: 463 PNRAGPGDRDPPTRGEES---RRRPT----GGRGRGPPPAPRPTSRYNSSSISSVLKDPD 515
++A PP RG+ES R P+ GGR G R R S SS
Sbjct: 346 RDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSS------ 399
Query: 516 SNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGLESDGPNMTENG 575
S P P PP + R SR R + + G + GP G
Sbjct: 400 --------ASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDS----GSGRGAPGP-----G 442
Query: 576 LEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRAESQSRQSAPLERTKPSE 635
E S +R + R R + + +S SR P R+ S
Sbjct: 443 PEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSS 502
Query: 636 DSLSGQKGDSVSKLPKGPSENGELSAPL 663
S S + S K P PS + PL
Sbjct: 503 RSPSKSRSRSAEKRPHSPSRSPSPKKPL 530
Score = 35.4 bits (80), Expect = 0.17
Identities = 52/213 (24%), Positives = 78/213 (36%), Gaps = 13/213 (6%)
Query: 395 PGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRG--RGRRTG-GPAYGPSSDVST 451
PGS RG GG K + + +T G++G RG G+ + P P S S+
Sbjct: 445 PGSERGHGGHGKRAKERPPRARPA--STSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSS 502
Query: 452 ASETESEKREEPNRAGPGDRDPPTRGEESRRRPTGGRGRGPPPAPRPTSRYNSSSISSVL 511
S ++S R R R P + SR + GR R A +R S S S +
Sbjct: 503 RSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRAR-HSEAEATRARRRSRSYSPIR 561
Query: 512 KDPDSNPYSLLD----TSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGLESD 567
K +P S ++ TS + P+ P P+S+ S T G
Sbjct: 562 KRRRDSP-SFMEPRRITSARKRPIPYY--RPSPSSSSSCLSSDYSTRSHSRSPSPGHSHG 618
Query: 568 GPNMTENGLEDESRPQRRNRSRRRRNRGNRTDG 600
+ +G +R R S +R + G
Sbjct: 619 SYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
>gi|239751791 PREDICTED: hypothetical protein [Homo sapiens]
Length = 650
Score = 47.8 bits (112), Expect = 3e-05
Identities = 50/157 (31%), Positives = 60/157 (38%), Gaps = 21/157 (13%)
Query: 402 GGSDKAGYSTDESSSSSLHAT---RTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETESE 458
G SD G SSS S G GG G G G A S S E +S+
Sbjct: 125 GVSDWRGSFLKLSSSRSTRGLVLGEGVGVGAGGEGGGEGAAGAASSLSERSSERVELQSD 184
Query: 459 KREEPNRAGPGDRDPPTRGEESRRRPTGGRG----RGPPPA---PRPTSRYNSSSISSVL 511
+ R G R P G S RRP G G RG PA RP+S+ SS S+
Sbjct: 185 TDDSDTRVAEGARPRP--GPTSSRRPWGRAGGLRPRGKRPARGKKRPSSQRRCSSPSAAR 242
Query: 512 KDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRS 548
TS P P S +P A ++RRR+
Sbjct: 243 ASA---------TSAPRPTAPSSVAQPSSARSQRRRA 270
>gi|239746282 PREDICTED: hypothetical protein XP_002343723 [Homo
sapiens]
Length = 725
Score = 47.8 bits (112), Expect = 3e-05
Identities = 50/157 (31%), Positives = 60/157 (38%), Gaps = 21/157 (13%)
Query: 402 GGSDKAGYSTDESSSSSLHAT---RTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETESE 458
G SD G SSS S G GG G G G A S S E +S+
Sbjct: 125 GVSDWRGSFLKLSSSRSTRGLVLGEGVGVGAGGEGGGEGAAGAASSLSERSSERVELQSD 184
Query: 459 KREEPNRAGPGDRDPPTRGEESRRRPTGGRG----RGPPPA---PRPTSRYNSSSISSVL 511
+ R G R P G S RRP G G RG PA RP+S+ SS S+
Sbjct: 185 TDDSDTRVAEGARPRP--GPTSSRRPWGRAGGLRPRGKRPARGKKRPSSQRRCSSPSAAR 242
Query: 512 KDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRS 548
TS P P S +P A ++RRR+
Sbjct: 243 ASA---------TSAPRPTAPSSVAQPSSARSQRRRA 270
>gi|169164483 PREDICTED: hypothetical protein [Homo sapiens]
Length = 324
Score = 47.4 bits (111), Expect = 4e-05
Identities = 40/135 (29%), Positives = 52/135 (38%), Gaps = 16/135 (11%)
Query: 419 LHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRD----PP 474
L A G +G +G G + GGP P S + +++R P R G R P
Sbjct: 124 LSAGAVQKGDFGPKGIGMKGGGPGLPPRGKASGPARDSAQQRRRPTRRPRGTRGGARRPG 183
Query: 475 TRGEESRR-RPTGGRGRGPPPA---PRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPP 530
RG+ + PTG R G PP+ P P R L+ P S P PP
Sbjct: 184 VRGQGAAAVGPTGPRPTGAPPSRRTPPPGPR-------RPLRSPHSGS-GWTPARPPSPP 235
Query: 531 VDSEPGEPPPASARR 545
+ PPAS R
Sbjct: 236 AGAPEALRPPASTTR 250
>gi|113414226 PREDICTED: hypothetical protein [Homo sapiens]
Length = 324
Score = 47.4 bits (111), Expect = 4e-05
Identities = 40/135 (29%), Positives = 52/135 (38%), Gaps = 16/135 (11%)
Query: 419 LHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRD----PP 474
L A G +G +G G + GGP P S + +++R P R G R P
Sbjct: 124 LSAGAVQKGDFGPKGIGMKGGGPGLPPRGKASGPARDSAQQRRRPTRRPRGTRGGARRPG 183
Query: 475 TRGEESRR-RPTGGRGRGPPPA---PRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPP 530
RG+ + PTG R G PP+ P P R L+ P S P PP
Sbjct: 184 VRGQGAAAVGPTGPRPTGAPPSRRTPPPGPR-------RPLRSPHSGS-GWTPARPPSPP 235
Query: 531 VDSEPGEPPPASARR 545
+ PPAS R
Sbjct: 236 AGAPEALRPPASTTR 250
>gi|239743051 PREDICTED: hypothetical protein XP_002342747 [Homo
sapiens]
Length = 306
Score = 47.4 bits (111), Expect = 4e-05
Identities = 54/214 (25%), Positives = 84/214 (39%), Gaps = 19/214 (8%)
Query: 430 GGRGRGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRDPPTRGEESRRRPTGGRG 489
GG G+ R +G PS+D A + E E P G R + ++ +RRP GG G
Sbjct: 45 GGTGQRRGSGS---SPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTG 101
Query: 490 RGPPPAPRPTSRYNSSSISSVLKDPDSN------PYSLLDTSEPEPPVDSEPGEPPPASA 543
+ R SR +SS+ +D + P S +E P + P +
Sbjct: 102 Q------RRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQ-CRPAAGTG 154
Query: 544 RRRRSRRRRTDEDRTVMDGGLESD-GPNMTENGLEDESRPQRRNRSRRRRNRGNRTDGSI 602
+RR S + + + D E+ P T +G E R + + + + G R
Sbjct: 155 QRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRS 214
Query: 603 SGDRQPVTVADYISRAESQSRQSAPLERTKPSED 636
S RQP R S+S SA +R + E+
Sbjct: 215 SPSRQPAGGTG--QRRGSRSSPSADQQRAQDREE 246
Score = 30.8 bits (68), Expect = 4.3
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 3/70 (4%)
Query: 433 GRGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRDPPTRGEESRRRPTGGRG--R 490
G G+R G + PS + + R P+ +D + +RRP GG G R
Sbjct: 205 GTGQRRGSRS-SPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRR 263
Query: 491 GPPPAPRPTS 500
G AP PT+
Sbjct: 264 GTAAAPVPTT 273
>gi|113413437 PREDICTED: hypothetical protein [Homo sapiens]
Length = 324
Score = 47.4 bits (111), Expect = 4e-05
Identities = 40/135 (29%), Positives = 52/135 (38%), Gaps = 16/135 (11%)
Query: 419 LHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRD----PP 474
L A G +G +G G + GGP P S + +++R P R G R P
Sbjct: 124 LSAGAVQKGDFGPKGIGMKGGGPGLPPRGKASGPARDSAQQRRRPTRRPRGTRGGARRPG 183
Query: 475 TRGEESRR-RPTGGRGRGPPPA---PRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPP 530
RG+ + PTG R G PP+ P P R L+ P S P PP
Sbjct: 184 VRGQGAAAVGPTGPRPTGAPPSRRTPPPGPR-------RPLRSPHSGS-GWTPARPPSPP 235
Query: 531 VDSEPGEPPPASARR 545
+ PPAS R
Sbjct: 236 AGAPEALRPPASTTR 250
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 46.2 bits (108), Expect = 1e-04
Identities = 67/264 (25%), Positives = 95/264 (35%), Gaps = 30/264 (11%)
Query: 395 PGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASE 454
PGS RG S D S S H + T +GR + G + GP S S +
Sbjct: 1493 PGSSRGGRQGSYHEQSVDRSGHSGYHHSHT-----TPQGRSDASHGQS-GPRS-ASRQTR 1545
Query: 455 TESEKREEPNRAGPGDRDPPTRGEESRRRPTGGRGRGPPPAPRPTSRYNSSSISSVLKDP 514
E + + +G +P TR SR G+G A TSR SS+S +D
Sbjct: 1546 NEEQSGDGSRHSGSRHHEPSTRAGSSRHSQV-GQGES---AGSKTSRRQGSSVS---QDR 1598
Query: 515 DSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGLE--------- 565
DS +S E + G S R+ R EDR E
Sbjct: 1599 DSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSH-QEDRASHGHSAESSRQSGTRH 1657
Query: 566 ---SDGPNMTENGLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRAESQS 622
S G + + S P R+ SR +++ + TD + V D +R S S
Sbjct: 1658 AETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGS 1717
Query: 623 RQSAPLERTKPSED---SLSGQKG 643
+ S ++ S+ S GQ G
Sbjct: 1718 QASDSEGHSEESDTQSVSAHGQAG 1741
Score = 40.0 bits (92), Expect = 0.007
Identities = 39/130 (30%), Positives = 52/130 (40%), Gaps = 22/130 (16%)
Query: 395 PGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASE 454
PGS RG S D S S H + T RG+ S S + +
Sbjct: 1817 PGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQ---------SGSRSVSRQ 1867
Query: 455 TESEKREEPNRAGPGDRDPPTRGEESRRRPTGGR----GRGPPPAPRPTSRYNSSSISSV 510
T +EK ++G G R +R E+ R R G+G PR TSR SS+S
Sbjct: 1868 TRNEK-----QSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPR-TSRNQGSSVS-- 1919
Query: 511 LKDPDSNPYS 520
+D DS +S
Sbjct: 1920 -QDSDSQGHS 1928
Score = 38.1 bits (87), Expect = 0.027
Identities = 78/343 (22%), Positives = 119/343 (34%), Gaps = 57/343 (16%)
Query: 352 ENISNAQALLEYHLSYLQEVEQLRLERLQIDEQLRQIGLGFRPPGSG------RGSGGS- 404
EN S QA + + E+ Q + R G+G S RGS GS
Sbjct: 2308 ENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQ 2367
Query: 405 --DKAGYSTDESSSS-SLHAT-----RTYGGSYGGRGRGR--RTGGPAYGPSSDVSTASE 454
D G+S D + S S H +++ S GR GR R+G Y VST +
Sbjct: 2368 ASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLY----QVSTHEQ 2423
Query: 455 TESEKREEPNRAGPGDRDPPTRGEESRRRPTGGRGR-------GPPPAPRPTSRYNS--- 504
+ES G + +S R T G+ G R S Y
Sbjct: 2424 SESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVD 2483
Query: 505 ---------SSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDE 555
S +S + S+ +S ++ + D + G+ S R R D
Sbjct: 2484 RSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADS 2543
Query: 556 DRTVMDGGLESDGPNMTEN------------GLEDESRPQRRNRSRRRRNRGNRTDGSIS 603
G +S+GP + N G ++S +R + S R + G+ +
Sbjct: 2544 SGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDS--ERWSGSASRNHHGSAQEQLRD 2601
Query: 604 GDRQPVTVADYISRA-ESQSRQSAPLERTKPSEDSLSGQKGDS 645
G R P + + RA S S+ T+ ++ S GQ S
Sbjct: 2602 GSRHPRSHQE--DRAGHGHSADSSRQSGTRHTQTSSGGQAASS 2642
Score = 37.7 bits (86), Expect = 0.035
Identities = 50/231 (21%), Positives = 83/231 (35%), Gaps = 27/231 (11%)
Query: 395 PGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASE 454
PGS RG S D S S H + T +GR ++G S S + E
Sbjct: 3762 PGSRRGGRQGSYHEQSVDRSGHSGSHHSHT-------TSQGRSDA--SHGQSGSRSASRE 3812
Query: 455 TESEKREEPNRAGPGDRDPPTRGEESRRRPTGGRGRGPPPAPRPTSRYNSSSISSVLKDP 514
T +E++ +G G R +R E+ + R SR + SSV +D
Sbjct: 3813 TRNEEQ-----SGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDS 3867
Query: 515 DSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGLESD-GPNMTE 573
DS Y P DSE +++R R D + G D ++
Sbjct: 3868 DSEAY----------PEDSE--RRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQS 3915
Query: 574 NGLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRAESQSRQ 624
+ ++ +S + + ++ + I P + + Y ++E RQ
Sbjct: 3916 SPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQ 3966
Score = 37.0 bits (84), Expect = 0.059
Identities = 68/315 (21%), Positives = 108/315 (34%), Gaps = 53/315 (16%)
Query: 378 RLQIDEQLRQIGLGFRPPGSG---------RGSGGSDKAGYSTDESSSSSLHATRTYGGS 428
+LQ + R G+G S GS SD G+S D + S +
Sbjct: 2010 QLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQ 2069
Query: 429 YGGRGRGRRTGGPAYGPSSD----VSTASETESEKREEPNRAGPGDRDPPTRGEESRRRP 484
+ R G + G S VST ++ES + G + ++S R
Sbjct: 2070 QSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHS 2129
Query: 485 TGGRGRGP---PPAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPA 541
G+ P P R S SV + S + TS+ D+ G+
Sbjct: 2130 ASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRS--DASRGQSGSR 2187
Query: 542 SARRRRSRRRRT------------------DEDRTVMDGGLESDGPNMTE---------- 573
SA R+ + ++ D R + G +S GP +
Sbjct: 2188 SASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDS 2247
Query: 574 --NGLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRA-ESQSRQSAPLER 630
G ++S +RR+ S R + G+ + S G R P + + RA S +S+
Sbjct: 2248 DSEGHSEDS--ERRSGSASRNHHGSAQEQSRDGSRHP--RSHHEDRAGHGHSAESSRQSG 2303
Query: 631 TKPSEDSLSGQKGDS 645
T +E+S GQ S
Sbjct: 2304 THHAENSSGGQAASS 2318
Score = 37.0 bits (84), Expect = 0.059
Identities = 53/212 (25%), Positives = 74/212 (34%), Gaps = 26/212 (12%)
Query: 395 PGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASE 454
PG RG S D S S H + T RG+ + S
Sbjct: 2142 PGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQ--------------SGSR 2187
Query: 455 TESEKREEPNRAGPGDRDPPTRGEESRRRPTGGR----GRGPPPAPRPTSRYNSSSISSV 510
+ S K + ++G G R + E+ R G+G PR TSR SS+S
Sbjct: 2188 SASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPR-TSRPRGSSVS-- 2244
Query: 511 LKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRT-DEDRTVMDGGLESDGP 569
+D DS +S + SE S R SR R+ EDR ES
Sbjct: 2245 -QDSDSEGHS--EDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQ 2301
Query: 570 NMTENGLEDESRPQRRNRSRRRRNRGNRTDGS 601
+ T + E+ S Q + + R+ GS
Sbjct: 2302 SGTHHA-ENSSGGQAASSHEQARSSAGERHGS 2332
Score = 32.0 bits (71), Expect = 1.9
Identities = 33/126 (26%), Positives = 47/126 (37%), Gaps = 14/126 (11%)
Query: 395 PGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASE 454
PGS RG +S D S S H + T +GR + G + S+ +T +E
Sbjct: 2790 PGSSRGGRQGYHHEHSVDSSGHSGSHHSHT-----TSQGRSDASRGQSGSRSASRTTRNE 2844
Query: 455 TESEKREEPNRAGPGDRDPPTRGEESRRRPTGGRGRGPPPAPRPTSRYNSSSISSVLKDP 514
+S G G R +R E+ R SR + SSV +D
Sbjct: 2845 EQS---------GDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDS 2895
Query: 515 DSNPYS 520
DS +S
Sbjct: 2896 DSEGHS 2901
Score = 32.0 bits (71), Expect = 1.9
Identities = 33/130 (25%), Positives = 47/130 (36%), Gaps = 22/130 (16%)
Query: 395 PGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASE 454
PGS R S D S S H + T RG+ + S
Sbjct: 3438 PGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQ--------------SGSR 3483
Query: 455 TESEKREEPNRAGPGDRDPPTRGEESRRRPTGGR----GRGPPPAPRPTSRYNSSSISSV 510
+ S + ++G G R + E+ + R G+G PR TSR SS+S
Sbjct: 3484 SASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPR-TSRNQGSSVS-- 3540
Query: 511 LKDPDSNPYS 520
+D DS +S
Sbjct: 3541 -QDSDSQGHS 3549
Score = 31.2 bits (69), Expect = 3.3
Identities = 55/235 (23%), Positives = 81/235 (34%), Gaps = 37/235 (15%)
Query: 386 RQIGLGFRPPG--SGRGSGGSDKAGYSTDESSSSSL--------------HATRTYGGSY 429
RQ R G GS SD G+S +ES + S+ + R + G
Sbjct: 1052 RQASSAVRDSGHWGSSGSQASDSEGHS-EESDTQSVSGHGQDGPHQQSHQESARDWSG-- 1108
Query: 430 GGRGRGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRDPPTRGEESRRRPTGGRG 489
GR R+G Y VST ++ES G + +S R G
Sbjct: 1109 ---GRSGRSGSFIY----QVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEG 1161
Query: 490 RGP---PPAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRR 546
+ P R R S SV + S + TS+ D+ G+
Sbjct: 1162 QDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRS--DASHGQSGS------ 1213
Query: 547 RSRRRRTDEDRTVMDGGLESDGPNMTENGLEDESRPQRRNRSRRRRNRGNRTDGS 601
RS R+T +D+ DG S + D SR + + + +R +R GS
Sbjct: 1214 RSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGS 1268
Score = 30.8 bits (68), Expect = 4.3
Identities = 50/211 (23%), Positives = 72/211 (34%), Gaps = 19/211 (9%)
Query: 400 GSGGSDKAGYSTDESSSSSLHATRTYGGSYGG-----RGRGRRTGGPAYGPSSDVSTASE 454
GS SD G+S +ES + S+ A G RG+ G + VST +
Sbjct: 1716 GSQASDSEGHS-EESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQ 1774
Query: 455 TESEKREEPNRAGPGDRDPPTRGEESRRRPTGGRG----RGPPPAPRPTSRYNSSSISSV 510
+ES G R + +S R G RG P + R R S SV
Sbjct: 1775 SESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRG-GRQGSHYEQSV 1833
Query: 511 LKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGLESDGPN 570
S + TS+ V RS R+T ++ DG S +
Sbjct: 1834 DSSGHSGSHHSHTTSQERSDVSR--------GQSGSRSVSRQTRNEKQSGDGSRHSGSRH 1885
Query: 571 MTENGLEDESRPQRRNRSRRRRNRGNRTDGS 601
+ D SR + + + R +R GS
Sbjct: 1886 HEASSRADSSRHSQVGQGQSSGPRTSRNQGS 1916
Score = 29.6 bits (65), Expect = 9.5
Identities = 32/126 (25%), Positives = 46/126 (36%), Gaps = 14/126 (11%)
Query: 395 PGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASE 454
PGS RG +S D S S H + T +GR + G + S+ +T +E
Sbjct: 3114 PGSSRGGRQGYHHEHSVDSSGHSGSHHSHT-----TSQGRSDASRGQSGSRSASRTTRNE 3168
Query: 455 TESEKREEPNRAGPGDRDPPTRGEESRRRPTGGRGRGPPPAPRPTSRYNSSSISSVLKDP 514
+S G R +R E+ R SR + SSV +D
Sbjct: 3169 EQS---------GDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDS 3219
Query: 515 DSNPYS 520
DS +S
Sbjct: 3220 DSEGHS 3225
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 45.8 bits (107), Expect = 1e-04
Identities = 64/279 (22%), Positives = 92/279 (32%), Gaps = 46/279 (16%)
Query: 414 SSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRDP 473
S S S TR+ S+ R R+ +Y P S +R P R P R
Sbjct: 280 SRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHR 339
Query: 474 PTRGEESRRR------------PTGGRGRGPPPAPRPTSRYNSSSISSVLKDPDSNPYSL 521
+R RRR + R R PP +P R +S + P ++P
Sbjct: 340 RSRSPVRRRRRSSASLSGSSSSSSSSRSRSPP--KKPPKRTSSPPRKTRRLSPSASPPR- 396
Query: 522 LDTSEPEPPVDSEP---GEPPPASARRRRSRRRRTDEDRT----VMDGGLE-------SD 567
P PP P P P + R R R RT G E +
Sbjct: 397 -RRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAP 455
Query: 568 GPNMTENGLEDESR---------PQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRA 618
P E +E + Q+R + RR+ + + GS S ++
Sbjct: 456 KPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNG 515
Query: 619 E-------SQSRQSAPLERTKPSEDSLSGQKGDSVSKLP 650
E S SR ++P R + E S G++ S S P
Sbjct: 516 EVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPP 554
Score = 39.7 bits (91), Expect = 0.009
Identities = 44/189 (23%), Positives = 68/189 (35%), Gaps = 44/189 (23%)
Query: 455 TESEKREEPNRAGPGDRDPPTRGEESRRRPTGGR----GRGPPPAPRPTSRYNSSSISSV 510
+ S +R + P R P R E R R R P PAP + SV
Sbjct: 169 SRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSV 228
Query: 511 -LKDPD----SNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGLE 565
+K+P ++ +L +PEP EP EP P ++ + +T
Sbjct: 229 KVKEPSVQEATSTSDILKVPKPEPI--PEPKEPSPEKNSKKEKEKEKT------------ 274
Query: 566 SDGPNMTENGLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRAESQSRQS 625
RP+ R+RS+ R +R+ R+ + SR+ S S +
Sbjct: 275 ---------------RPRSRSRSKSRSRTRSRSPSHTRPRRR------HRSRSRSYSPRR 313
Query: 626 APLERTKPS 634
P R +PS
Sbjct: 314 RPSPRRRPS 322
Score = 37.4 bits (85), Expect = 0.045
Identities = 73/287 (25%), Positives = 89/287 (31%), Gaps = 52/287 (18%)
Query: 410 STDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPG 469
S+D SSSS R GRR + PS S + ++ R
Sbjct: 493 SSDSGSSSSSEDERPKRSHVKNGEVGRRR---RHSPSRSASPSPRKRQKETSPRGRRRRS 549
Query: 470 DRDPPTRGEES---------RRRPTGG---RGRGPPPAPR-PTSRYNSSSISSVLKDPDS 516
PPTR S RR PT R PPP R P+ R S I + S
Sbjct: 550 PSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQR--RYSPS 607
Query: 517 NPYSLLDTSEPEPPVDSEPGEPPP--------------------------ASARRRRSRR 550
P S P PP PPP + R+ S
Sbjct: 608 PPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPS 667
Query: 551 RRTDEDRTVMDGGLESDGPNMTENGLEDESRPQRRNRS---RRRRNRGNRTDGSISGDRQ 607
R T E R+ S P P RR S +RR++ T R
Sbjct: 668 RSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRT 727
Query: 608 PVTVADYISRAESQSRQSAPLERTKPSEDSLSGQKGDSVSKLPKGPS 654
P I +A S S QS R S S+SG + K P PS
Sbjct: 728 P--EPKKIKKAASPSPQSV---RRVSSSRSVSGSPEPAAKKPPAPPS 769
Score = 32.0 bits (71), Expect = 1.9
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 7/75 (9%)
Query: 577 EDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRAESQSRQSAPLERTKPSED 636
E ES ++R RSR R R +R+ P + + R +S +P RTK
Sbjct: 158 EKESSREKRERSRSPRRRKSRSPS-------PRRRSSPVRRERKRSHSRSPRHRTKSRSP 210
Query: 637 SLSGQKGDSVSKLPK 651
S + +K + +LP+
Sbjct: 211 SPAPEKKEKTPELPE 225
>gi|239757337 PREDICTED: hypothetical protein XP_002345251 [Homo
sapiens]
Length = 330
Score = 45.4 bits (106), Expect = 2e-04
Identities = 66/221 (29%), Positives = 80/221 (36%), Gaps = 30/221 (13%)
Query: 411 TDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDV--STASETE---SEKREEPNR 465
T SS S+L R +GG GRG A G ++ + STAS E S ++
Sbjct: 2 TSFSSRSALGRQRAWGGCVPGRGSASGLAAAASGRAASMTPSTASSMEGPRSRWKDSSGS 61
Query: 466 AGPGDRDPPTRGEESRR-RPTG---GRGRGPPP------------APRPTSRYNSSSISS 509
AG G D T G R P G G G GPPP PRPT S S
Sbjct: 62 AGEGAADCGTAGGGGERGAPAGGARGSGGGPPPWRLRNEVSPKASPPRPTCSVCRKSPSG 121
Query: 510 VLKDPDSNPYSLLDTSEPEP-PVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGLESDG 568
D L + P G ++A R S+ R +D DGG G
Sbjct: 122 AEMDRAPRSGRFLGCAGPSCFSTGICEGHGRVSAAPARGSQPRDCSKD----DGGRFPPG 177
Query: 569 PNMTENGLEDESRPQRRNRSRRRRNRGNRTDGSIS-GDRQP 608
P TE S P S+ R N G G GD +P
Sbjct: 178 PARTEITTHSRSGP---TGSQTRGNCGAAGSGDPRWGDPRP 215
>gi|239751874 PREDICTED: hypothetical protein XP_002348034 [Homo
sapiens]
Length = 330
Score = 45.4 bits (106), Expect = 2e-04
Identities = 66/221 (29%), Positives = 80/221 (36%), Gaps = 30/221 (13%)
Query: 411 TDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDV--STASETE---SEKREEPNR 465
T SS S+L R +GG GRG A G ++ + STAS E S ++
Sbjct: 2 TSFSSRSALGRQRAWGGCVPGRGSASGLAAAASGRAASMTPSTASSMEGPRSRWKDSSGS 61
Query: 466 AGPGDRDPPTRGEESRR-RPTG---GRGRGPPP------------APRPTSRYNSSSISS 509
AG G D T G R P G G G GPPP PRPT S S
Sbjct: 62 AGEGAADCGTAGGGGERGAPAGGARGSGGGPPPWRLRNEVSPKASPPRPTCSVCRKSPSG 121
Query: 510 VLKDPDSNPYSLLDTSEPEP-PVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGLESDG 568
D L + P G ++A R S+ R +D DGG G
Sbjct: 122 AEMDRAPRSGRFLGCAGPSCFSTGICEGHGRVSAAPARGSQPRDCSKD----DGGRFPPG 177
Query: 569 PNMTENGLEDESRPQRRNRSRRRRNRGNRTDGSIS-GDRQP 608
P TE S P S+ R N G G GD +P
Sbjct: 178 PARTEITTHSRSGP---TGSQTRGNCGAAGSGDPRWGDPRP 215
>gi|239754474 PREDICTED: similar to mucin [Homo sapiens]
Length = 417
Score = 45.1 bits (105), Expect = 2e-04
Identities = 44/173 (25%), Positives = 68/173 (39%), Gaps = 15/173 (8%)
Query: 433 GRGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRDPPTRGEESRRRPTGG----R 488
G G+R G + PS+D A + E E P G R + ++ +RRP GG R
Sbjct: 117 GTGQRRGSRS-SPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRR 175
Query: 489 GRGPPPAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRS 548
G G P+ + ++ P S + + +P+ P P + +RR S
Sbjct: 176 GSGSSPSADQQGAQDREEEAAAAPAPTSRGHR-TEKRKPQQP----QCRPAGGTGQRRGS 230
Query: 549 RRRRTDEDRTVMDGGLE-SDGPNMTENGLEDESR----PQRRNRSRRRRNRGN 596
R + + + D E + P T G E R PQRR + RG+
Sbjct: 231 RSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGS 283
Score = 42.4 bits (98), Expect = 0.001
Identities = 57/259 (22%), Positives = 93/259 (35%), Gaps = 39/259 (15%)
Query: 396 GSGRGSGGS---DKAGYSTDESSSSSLHATRTYGGSYGGR-----------GRGRRTGGP 441
G RGSG S D+ G E +++ A + G R G G+R G
Sbjct: 172 GQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSR 231
Query: 442 AYGPSSDVSTASETESEKREEPNRAGPGDRDPPTRGEESRRRPTGGRGRGPPPAPRPTSR 501
+ PS+D A + E E P G R + ++ +RRP GG G+ R S
Sbjct: 232 S-SPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQ------RRGSG 284
Query: 502 YNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMD 561
Y+ S+ +D + + P P S+ R +R+R
Sbjct: 285 YSPSADQQGAQDRE----------------EEAAAAPAPTSSGHRTEKRKRLQLQCQPAG 328
Query: 562 GGLESDGPNMTENGLED--ESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRAE 619
G + G + + + + R + + + G+RT+ Q A R
Sbjct: 329 GTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRG 388
Query: 620 SQSRQSAPLERTKPSEDSL 638
S S SA +R + E+ +
Sbjct: 389 SGSSPSADQQRAQDREEEV 407
Score = 35.4 bits (80), Expect = 0.17
Identities = 49/230 (21%), Positives = 79/230 (34%), Gaps = 37/230 (16%)
Query: 432 RGRGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRDPPTRGEESRRRPTGGRGRG 491
+G R A P++D A + E E P G R + + + +P GG G+
Sbjct: 62 QGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQ- 120
Query: 492 PPPAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRR 551
R SR + S+ D + + P P S R +R+
Sbjct: 121 -----RRGSRSSPSA----------------DQQRAQDREEEAAAAPVPTSRGHRTEKRK 159
Query: 552 RTDEDRTVMDGGLESDG----PNMTENGLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQ 607
R R G + G P+ + G +D R + + +RG+RT+ R+
Sbjct: 160 RQQPQRRPAGGTGQRRGSGSSPSADQQGAQD--REEEAAAAPAPTSRGHRTE-----KRK 212
Query: 608 PVTVADYISRAESQSRQSAPLERTKPSEDSLSGQKGDSVSKLPKGPSENG 657
P + Q R S R+ PS D Q + + P+ G
Sbjct: 213 PQQPQCRPAGGTGQRRGS----RSSPSADQQRAQDREEEAAAAPAPTSRG 258
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 44.7 bits (104), Expect = 3e-04
Identities = 58/257 (22%), Positives = 90/257 (35%), Gaps = 12/257 (4%)
Query: 395 PGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASE 454
P S S G+D A +D +SSS A+ S G G + G D + S+
Sbjct: 465 PNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDN-GNGSDSKG---AEDDDSDSTSD 520
Query: 455 TESEKREEPNRAGPGDRDPPTRGE------ESRRRPTGGRGRGPPPAPRPTSRYNSSSIS 508
T + G D D G+ +S + + +S NSSS S
Sbjct: 521 TNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDS 580
Query: 509 SVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGLESDG 568
D DS+ S D+S+ DS S+ S ++D ++ D
Sbjct: 581 DS-SDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSK 639
Query: 569 PNMTENGLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRAESQSRQSAPL 628
+ +++ D S + S N + +D S S D + + S S S S+
Sbjct: 640 SDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN-SSDSSDSSDSSNS 698
Query: 629 ERTKPSEDSLSGQKGDS 645
+ S DS DS
Sbjct: 699 SESSDSSDSSDSDSSDS 715
Score = 41.6 bits (96), Expect = 0.002
Identities = 54/267 (20%), Positives = 88/267 (32%), Gaps = 4/267 (1%)
Query: 397 SGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETE 456
S S SD + S +S SS + + S + SSD S +S +
Sbjct: 607 SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666
Query: 457 SEKREEPNRAGPGDRDPPTRGEESRRRPTGGRGRGPPPAPRPTSRYNSSSISSVLKDPDS 516
+ D + S + + S + SS SS DS
Sbjct: 667 DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDS 726
Query: 517 NPYSLLDTSEPEPPVD-SEPGEPPPASARRRRSRRRRTDEDRTVMDGGLESDGPNMTE-N 574
+ + D+S+ D S+ + +S S + + D SD N ++ N
Sbjct: 727 DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSN 786
Query: 575 GLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRAESQSRQSAPLERTKPS 634
+ S + S N + +D S S D +D S S S S+ + S
Sbjct: 787 DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSD--SSNSSDSSDSSNSSDSSDS 844
Query: 635 EDSLSGQKGDSVSKLPKGPSENGELSA 661
DS G DS ++ S + S+
Sbjct: 845 SDSSDGSDSDSSNRSDSSNSSDSSDSS 871
Score = 39.7 bits (91), Expect = 0.009
Identities = 52/265 (19%), Positives = 86/265 (32%), Gaps = 12/265 (4%)
Query: 397 SGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETE 456
S S SD + S SS+S ++ + S + S S+ S
Sbjct: 770 SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNS 829
Query: 457 SEKREEPNRAGPGDRDPPTRGEESRRRPTGGRGRGPPPAPRPTSRYNSSSISSVLKDPDS 516
S+ + N + D + G +S + S +S S S + S
Sbjct: 830 SDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESS 889
Query: 517 NPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGLESDGPNMTENGL 576
N D+S+ DS+ + +S S + E D SD N +++
Sbjct: 890 NSS---DSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSD 946
Query: 577 EDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRAESQSRQSAPLERTKPSED 636
+ S + N +D S S D +D S + + S S + + S+
Sbjct: 947 SSD--------SSNSSDSSNSSDSSNSSDSSDSNSSD-SSDSSNSSDSSDSSDSSDSSDS 997
Query: 637 SLSGQKGDSVSKLPKGPSENGELSA 661
S S DS S N S+
Sbjct: 998 SDSSNSSDSSDSSDSSDSSNSSDSS 1022
Score = 37.0 bits (84), Expect = 0.059
Identities = 48/251 (19%), Positives = 84/251 (33%), Gaps = 4/251 (1%)
Query: 397 SGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETE 456
S S SD + S +SS S ++ + S + +S S+ S
Sbjct: 923 SSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNS 982
Query: 457 SEKREEPNRAGPGDRDPPTRGEESRRRPTGGRGRGPPPAPRPTSRYNSSSISSVLKDPDS 516
S+ + + + D + +S + + NSS S DS
Sbjct: 983 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042
Query: 517 NPYS-LLDTSEPEPPVD-SEPGEPPPASARRRRSRRRRTDEDRTVMDGGLESDGPNMTEN 574
+ S D+S+ D S+ + +S S + E D SD + +++
Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS 1102
Query: 575 GLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRAESQSRQSAPLERTKPS 634
D S + S + N +D S S D + + S + S S + + S
Sbjct: 1103 --SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSS 1160
Query: 635 EDSLSGQKGDS 645
+ S S DS
Sbjct: 1161 DSSDSSDSSDS 1171
Score = 33.9 bits (76), Expect = 0.50
Identities = 48/267 (17%), Positives = 86/267 (32%), Gaps = 4/267 (1%)
Query: 397 SGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETE 456
S S S+ + S + +SS S +++ + S + S + S
Sbjct: 917 SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDS 976
Query: 457 SEKREEPNRAGPGDRDPPTRGEESRRRPTGGRGRGPPPAPRPTSRYNSSSISSVLKDPDS 516
S+ + + D + +S + + NSS S+ DS
Sbjct: 977 SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS 1036
Query: 517 NPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGLESDGPNMTENGL 576
+ S D+S+ DS S+ S D + ES + + N
Sbjct: 1037 SDSS--DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSS 1094
Query: 577 E--DESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRAESQSRQSAPLERTKPS 634
+ D S + S + + +D S S D + + S + + S S E + S
Sbjct: 1095 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154
Query: 635 EDSLSGQKGDSVSKLPKGPSENGELSA 661
+ S S DS S + S+
Sbjct: 1155 DSSDSSDSSDSSDSSDSSDSSDSSNSS 1181
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 44.7 bits (104), Expect = 3e-04
Identities = 67/302 (22%), Positives = 110/302 (36%), Gaps = 34/302 (11%)
Query: 375 RLERLQIDEQLRQIGLGFRPPGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGR 434
R R Q D Q R + P SG D+ G SSS H R + G
Sbjct: 746 RRRRAQDDSQRRSL------PAEEGSSGKKDEGG----GGSSSQDHGGRKHKGELPPSSC 795
Query: 435 GRRTGGPAYGPSSDVSTASETESEK---------REEPNRAGPGDRDPPTRGEESRRRPT 485
RR G SS S S + + ++ P++ + + + E SR R
Sbjct: 796 QRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSR 855
Query: 486 GGRGRGPPPAPRPTSRYNSSSISSV----------LKDPDSNPYSLLDTSEPEPPVDSEP 535
GR + R + Y+SSS +S D + YS + DS+
Sbjct: 856 SGRRHSSHRSSRRS--YSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDD 913
Query: 536 GEPPPASARRRRSRRRRTDEDRTVMDGGLESDGPNMTENGLEDESRPQRRNRSRRRRNRG 595
+ + R +R + +D+D ++ S + T R + + SR R R
Sbjct: 914 SDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRR 973
Query: 596 NRTDGSISGDRQPVTVADYISRAESQSRQSAPLERT---KPSEDSLSGQKGDSVSKLPKG 652
+R+ + S R D S S++S +R+ + E+ SG++ SK+ +
Sbjct: 974 SRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRS 1033
Query: 653 PS 654
S
Sbjct: 1034 QS 1035
Score = 36.2 bits (82), Expect = 0.10
Identities = 57/264 (21%), Positives = 89/264 (33%), Gaps = 48/264 (18%)
Query: 422 TRTYGGSYGGRGRGRRTGGPAYGPSSDV--------STASETESEKREEPNRAGPGDRDP 473
++ GG R G R PA G + S SETE R P++ +
Sbjct: 614 SKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSH 673
Query: 474 PTRGEESRRRPTGGRGRGPPPAPRPTSRYNSSSISSVLK------DPDSNPYSLLDTSEP 527
+ ++ ++ + + + +S+ S S K + S P +P
Sbjct: 674 RHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKP 733
Query: 528 EPPVDSEPGEPPPASARRRRSRRRRTDEDRTVM--------------DGGLESDGPNMTE 573
EPP P P RR RR + D R + G D
Sbjct: 734 EPPGSGSPAPP-------RRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKH 786
Query: 574 NGLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRAESQSRQSAPLERTKP 633
G S QRR ++R +R+ S SGD +S S L + P
Sbjct: 787 KGELPPSSCQRRAGTKRSSRSSHRSQPS-SGDE------------DSDDASSHRLHQKSP 833
Query: 634 SEDSLSGQKGDSVSKLPKGPSENG 657
S+ S ++ DS S+ + S +G
Sbjct: 834 SQYSEEEEEEDSGSEHSRSRSRSG 857
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 44.3 bits (103), Expect = 4e-04
Identities = 36/114 (31%), Positives = 44/114 (38%), Gaps = 18/114 (15%)
Query: 430 GGRGRGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRDPP-TRGEESRRRPTGGR 488
GGRGRGR G P D P AGPG PP G+ R P G
Sbjct: 200 GGRGRGRFPGAV---PGGD------------RFPGPAGPGGPPPPFPAGQTPPRPPLGPP 244
Query: 489 GRGPPPAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEP--EPPVDSEPGEPPP 540
G PP P P + ++ D P +L +P +PP+ P PPP
Sbjct: 245 GPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPP 298
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 44.3 bits (103), Expect = 4e-04
Identities = 63/287 (21%), Positives = 100/287 (34%), Gaps = 33/287 (11%)
Query: 393 RPPGSGRGSGGSDKAGYSTDESSSSSLHATRTYG--GSYGGRGRGRRTGGPAYGPSSDVS 450
RPPGS R A A R G G+ G + R GG G ++
Sbjct: 28 RPPGSPRPPPPVTPA-------------ALRVLGAAGAVGRKPLAERAGG--IGGATIPE 72
Query: 451 TASETESEKREEPNRAGPGDRDPPTRGEESRRRPTGGRGRG---PPPAPRPTSRYNSSSI 507
+A + P +G G+R PP + + GR G P P + R ++
Sbjct: 73 SAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 132
Query: 508 SSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGLE-- 565
+ K ++ S L PG P PA ARR R+ R
Sbjct: 133 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 192
Query: 566 SDGPNMTENGLEDESRPQRRNRSRRRRNRG----NRTDGSISGDRQPVTVADYISRAESQ 621
++GP + + + S + +RRR + G S+S P++ + S ++
Sbjct: 193 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS-SPARSGPSAR 251
Query: 622 SRQSAPLERTKPSEDSLSGQKGDSVSKLPK------GPSENGELSAP 662
AP ++P L + V+ K GP + L+ P
Sbjct: 252 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 298
Score = 32.7 bits (73), Expect = 1.1
Identities = 29/80 (36%), Positives = 31/80 (38%), Gaps = 17/80 (21%)
Query: 471 RDPPTRGEE---SRRRPTGGRGRGPPPAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEP 527
R PPT G + S R T GPPP P S S SS L PD +S TS P
Sbjct: 548 RRPPTPGPDTSVSGPRLTLALAPGPPPPP-------SRSPSSTLSGPDLAGHSSSATSTP 600
Query: 528 EP-------PVDSEPGEPPP 540
E P PPP
Sbjct: 601 EELRGYDSGPEGGAAASPPP 620
>gi|48255931 hepatoma-derived growth factor-related protein 2
isoform 1 [Homo sapiens]
Length = 671
Score = 44.3 bits (103), Expect = 4e-04
Identities = 73/289 (25%), Positives = 98/289 (33%), Gaps = 60/289 (20%)
Query: 411 TDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGD 470
+D+SS +S +T R R+ + VS + E SE E + D
Sbjct: 146 SDKSSDNSGLKRKTPALKMSVSKRARKASSDL--DQASVSPSEEENSESSSESEKTSDQD 203
Query: 471 RDPPTRG--EESRRRPTGGRGRGPPPA--------------PRPTSRYNSSSISSVLKDP 514
P + RR P GGR + P+ P P + S+S SS
Sbjct: 204 FTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSS----- 258
Query: 515 DSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRR------TDEDRTVMDG------ 562
S+ S D S +PP +P E P R R+ + R +D D +D
Sbjct: 259 SSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSSSSDSDSDEVDRISEWKR 318
Query: 563 -------GLESDGPNMTENGL----EDESRPQRRNRSRRRRNRGNRTDGSISGDR----- 606
LE+ E L E E + R R R R R G SGD
Sbjct: 319 RDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAERGSGGSSGDELREDD 378
Query: 607 QPVTVADYISR-----AESQSRQSAPLERTKPSEDSLSGQKGDSVSKLP 650
+PV R + S S A LER E S +K S S P
Sbjct: 379 EPVKKRGRKGRGRGPPSSSDSEPEAELER----EAKKSAKKPQSSSTEP 423
>gi|14249158 hepatoma-derived growth factor-related protein 2
isoform 2 [Homo sapiens]
Length = 670
Score = 44.3 bits (103), Expect = 4e-04
Identities = 73/289 (25%), Positives = 98/289 (33%), Gaps = 60/289 (20%)
Query: 411 TDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGD 470
+D+SS +S +T R R+ + VS + E SE E + D
Sbjct: 146 SDKSSDNSGLKRKTPALKMSVSKRARKASSDL--DQASVSPSEEENSESSSESEKTSDQD 203
Query: 471 RDPPTRG--EESRRRPTGGRGRGPPPA--------------PRPTSRYNSSSISSVLKDP 514
P + RR P GGR + P+ P P + S+S SS
Sbjct: 204 FTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSS----- 258
Query: 515 DSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRR------TDEDRTVMDG------ 562
S+ S D S +PP +P E P R R+ + R +D D +D
Sbjct: 259 SSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSSSSDSDSDEVDRISEWKR 318
Query: 563 -------GLESDGPNMTENGL----EDESRPQRRNRSRRRRNRGNRTDGSISGDR----- 606
LE+ E L E E + R R R R R G SGD
Sbjct: 319 RDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAERGSGGSSGDELREDD 378
Query: 607 QPVTVADYISR-----AESQSRQSAPLERTKPSEDSLSGQKGDSVSKLP 650
+PV R + S S A LER E S +K S S P
Sbjct: 379 EPVKKRGRKGRGRGPPSSSDSEPEAELER----EAKKSAKKPQSSSTEP 423
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.132 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,132,153
Number of Sequences: 37866
Number of extensions: 1681876
Number of successful extensions: 12140
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 108
Number of HSP's successfully gapped in prelim test: 924
Number of HSP's that attempted gapping in prelim test: 9556
Number of HSP's gapped (non-prelim): 2889
length of query: 673
length of database: 18,247,518
effective HSP length: 109
effective length of query: 564
effective length of database: 14,120,124
effective search space: 7963749936
effective search space used: 7963749936
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.