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Search of human proteins with 4757936
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4757936 cyclin G2 [Homo sapiens]
(344 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4757936 cyclin G2 [Homo sapiens] 697 0.0
gi|40805832 cyclin G1 [Homo sapiens] 295 4e-80
gi|4757934 cyclin G1 [Homo sapiens] 295 4e-80
gi|5802992 cyclin I [Homo sapiens] 123 2e-28
gi|89886237 cyclin I family, member 2 [Homo sapiens] 89 6e-18
gi|153791755 cyclin domain containing [Homo sapiens] 59 8e-09
gi|4757930 cyclin B2 [Homo sapiens] 56 5e-08
gi|17318565 cyclin E2 [Homo sapiens] 54 3e-07
gi|161377472 cyclin A1 isoform c [Homo sapiens] 54 3e-07
gi|161377470 cyclin A1 isoform c [Homo sapiens] 54 3e-07
gi|161377468 cyclin A1 isoform b [Homo sapiens] 54 3e-07
gi|4502611 cyclin A1 isoform a [Homo sapiens] 54 3e-07
gi|4502613 cyclin A [Homo sapiens] 51 1e-06
gi|17318559 cyclin E1 isoform 1 [Homo sapiens] 49 5e-06
gi|17318561 cyclin E1 isoform 2 [Homo sapiens] 49 5e-06
gi|4502617 cyclin D2 [Homo sapiens] 47 2e-05
gi|16950655 cyclin D1 [Homo sapiens] 45 7e-05
gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 45 7e-05
gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho... 43 4e-04
gi|14327896 cyclin B1 [Homo sapiens] 39 0.009
gi|197276676 cyclin J isoform 3 [Homo sapiens] 38 0.015
gi|197276674 cyclin J isoform 1 [Homo sapiens] 38 0.015
gi|40254889 cyclin J isoform 2 [Homo sapiens] 38 0.015
gi|209862835 cyclin D3 isoform 1 [Homo sapiens] 37 0.020
gi|208431829 eukaryotic translation initiation factor 2-alpha ki... 31 1.4
gi|24308527 stereocilin [Homo sapiens] 30 2.4
gi|157426885 organic cation transporter like 4 [Homo sapiens] 30 3.2
gi|55741473 HECT, C2 and WW domain containing E3 ubiquitin prote... 30 4.1
gi|116517325 olfactory receptor, family 4, subfamily S, member 2... 29 5.4
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 29 7.0
>gi|4757936 cyclin G2 [Homo sapiens]
Length = 344
Score = 697 bits (1799), Expect = 0.0
Identities = 344/344 (100%), Positives = 344/344 (100%)
Query: 1 MKDLGAEHLAGHEGVQLLGLLNVYLEQEERFQPREKGLSLIEATPENDNTLCPGLRNAKV 60
MKDLGAEHLAGHEGVQLLGLLNVYLEQEERFQPREKGLSLIEATPENDNTLCPGLRNAKV
Sbjct: 1 MKDLGAEHLAGHEGVQLLGLLNVYLEQEERFQPREKGLSLIEATPENDNTLCPGLRNAKV 60
Query: 61 EDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIP 120
EDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIP
Sbjct: 61 EDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIP 120
Query: 121 STHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTSERKEIL 180
STHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTSERKEIL
Sbjct: 121 STHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTSERKEIL 180
Query: 181 SLDKLEAQLKACNCRLIFSKAKPSVLALCLLNLEVETLKSVELLEILLLVKKHSKINDTE 240
SLDKLEAQLKACNCRLIFSKAKPSVLALCLLNLEVETLKSVELLEILLLVKKHSKINDTE
Sbjct: 181 SLDKLEAQLKACNCRLIFSKAKPSVLALCLLNLEVETLKSVELLEILLLVKKHSKINDTE 240
Query: 241 FFYWRELVSKCLAEYSSPECCKPDLKKLVWIVSRRTAQNLHNSYYSVPELPTIPEGGCFD 300
FFYWRELVSKCLAEYSSPECCKPDLKKLVWIVSRRTAQNLHNSYYSVPELPTIPEGGCFD
Sbjct: 241 FFYWRELVSKCLAEYSSPECCKPDLKKLVWIVSRRTAQNLHNSYYSVPELPTIPEGGCFD 300
Query: 301 ESESEDSCEDMSCGEESLSSSPPSDQECTFFFNFKVAQTLCFPS 344
ESESEDSCEDMSCGEESLSSSPPSDQECTFFFNFKVAQTLCFPS
Sbjct: 301 ESESEDSCEDMSCGEESLSSSPPSDQECTFFFNFKVAQTLCFPS 344
>gi|40805832 cyclin G1 [Homo sapiens]
Length = 295
Score = 295 bits (755), Expect = 4e-80
Identities = 153/290 (52%), Positives = 209/290 (72%), Gaps = 1/290 (0%)
Query: 7 EHLAGHEGVQLLGLLNVYLEQEERFQPREKGLSLIEATPENDNTLCPGLRNAKVEDLRSL 66
E L + +LL LN LEQE R QP+ GL LIE+ +N + LR+ +V+DL SL
Sbjct: 3 EVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSL 62
Query: 67 ANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVI 126
FFG TETF LAVN+LDRFL+ MKV+PKHL C+G+ F LA + +EE+ N+P D+I
Sbjct: 63 TQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLI 122
Query: 127 RISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTS-ERKEILSLDKL 185
RISQ + T SD+ RMEKI+ EK+ ++++ATTA FL LY++++ + ER+ ++ ++L
Sbjct: 123 RISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERL 182
Query: 186 EAQLKACNCRLIFSKAKPSVLALCLLNLEVETLKSVELLEILLLVKKHSKINDTEFFYWR 245
EAQLKAC+CR+IFSKAKPSVLAL ++ LE++ K VEL E + ++KHSKIN + +W+
Sbjct: 183 EAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRDLTFWQ 242
Query: 246 ELVSKCLAEYSSPECCKPDLKKLVWIVSRRTAQNLHNSYYSVPELPTIPE 295
ELVSKCL EYSS +C KP+++KL WIVS RTA+ L +SYY + LPTIPE
Sbjct: 243 ELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPE 292
>gi|4757934 cyclin G1 [Homo sapiens]
Length = 295
Score = 295 bits (755), Expect = 4e-80
Identities = 153/290 (52%), Positives = 209/290 (72%), Gaps = 1/290 (0%)
Query: 7 EHLAGHEGVQLLGLLNVYLEQEERFQPREKGLSLIEATPENDNTLCPGLRNAKVEDLRSL 66
E L + +LL LN LEQE R QP+ GL LIE+ +N + LR+ +V+DL SL
Sbjct: 3 EVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSL 62
Query: 67 ANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVI 126
FFG TETF LAVN+LDRFL+ MKV+PKHL C+G+ F LA + +EE+ N+P D+I
Sbjct: 63 TQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLI 122
Query: 127 RISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTS-ERKEILSLDKL 185
RISQ + T SD+ RMEKI+ EK+ ++++ATTA FL LY++++ + ER+ ++ ++L
Sbjct: 123 RISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERL 182
Query: 186 EAQLKACNCRLIFSKAKPSVLALCLLNLEVETLKSVELLEILLLVKKHSKINDTEFFYWR 245
EAQLKAC+CR+IFSKAKPSVLAL ++ LE++ K VEL E + ++KHSKIN + +W+
Sbjct: 183 EAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRDLTFWQ 242
Query: 246 ELVSKCLAEYSSPECCKPDLKKLVWIVSRRTAQNLHNSYYSVPELPTIPE 295
ELVSKCL EYSS +C KP+++KL WIVS RTA+ L +SYY + LPTIPE
Sbjct: 243 ELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPE 292
>gi|5802992 cyclin I [Homo sapiens]
Length = 377
Score = 123 bits (309), Expect = 2e-28
Identities = 81/227 (35%), Positives = 126/227 (55%), Gaps = 15/227 (6%)
Query: 41 IEATPENDNTLCPGLRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSC 100
+ P N N + P R+ ++ L L F ETF LA ++LDRFLA +K PK+LSC
Sbjct: 31 VRKMPSNQN-VSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSC 89
Query: 101 IGVCSFLLAARIVEEDCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALN 160
I + F LAA+ VEED IP + R S C C++S+I RME+II +KL+++L T L+
Sbjct: 90 IAISCFFLAAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLD 149
Query: 161 FLHLYHTII----------LCHTSERKEILSLDKLEAQLKACNCRLIFSKAKPSVLALCL 210
FLH++H I L S + + L K ACN L F + S+LAL +
Sbjct: 150 FLHIFHAIAVSTRPQLLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQF---RGSMLALAM 206
Query: 211 LNLEVETLKSVELLEILLLVKKHSKINDTEFFYWRELVSKCLAEYSS 257
++LE+E L + L + + + + ++++ ++ + RELV+ L+ S
Sbjct: 207 VSLEMEKL-IPDWLSLTIELLQKAQMDSSQLIHCRELVAHHLSTLQS 252
>gi|89886237 cyclin I family, member 2 [Homo sapiens]
Length = 369
Score = 89.0 bits (219), Expect = 6e-18
Identities = 66/205 (32%), Positives = 102/205 (49%), Gaps = 8/205 (3%)
Query: 63 LRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPST 122
L L N F TF LA+ I R L +KVK K+L C + S LAA++ EE+ IP
Sbjct: 157 LLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQV 216
Query: 123 HDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILC---HTSE---- 175
D + + +++ RME I ++LH++L T L+FL ++H +++ H E
Sbjct: 217 KDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELLPQ 276
Query: 176 RKEILSLDKLEAQLKACNCRLIFSKAKPSVLALCLLNLEVETLKSVELLEILLLVKKHSK 235
R L + L QL+ C + K S LAL ++ LE+E L I L+KK ++
Sbjct: 277 RNPSLHVASLTRQLQHCMAGHQLLQFKGSTLALVIITLELERLMPGWCAPISDLLKK-AQ 335
Query: 236 INDTEFFYWRELVSKCLAEYSSPEC 260
+ D ++ +ELV + L S C
Sbjct: 336 VGDMQYSCCKELVMQQLRSLQSSSC 360
>gi|153791755 cyclin domain containing [Homo sapiens]
Length = 350
Score = 58.5 bits (140), Expect = 8e-09
Identities = 57/197 (28%), Positives = 82/197 (41%), Gaps = 16/197 (8%)
Query: 27 QEERFQPREKGLSLIEATPENDNTLCPGLRNAKVEDLRSLANFFGSCTETFVLAVNILDR 86
QE F PRE + T E+ R + L + FG E+ L VN LDR
Sbjct: 112 QESHFHPREALARQPQVTAES--------RCKLLSWLIPVHRQFGLSFESLCLTVNTLDR 163
Query: 87 FLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVIRISQCKCTASDIKRMEKIIS 146
FL V +GV S L+A + VE + P ++ + + + +E I+
Sbjct: 164 FLTTTPVAADCFQLLGVTSLLIACKQVE--VHPPRVKQLLALCCGAFSRQQLCNLECIVL 221
Query: 147 EKLHYELEATTALNFL-HLYHTIILCHTSERKEILSLDKLE---AQLKACNCRLIFSKAK 202
KLH+ L A T FL H H + +E E L L A+L + F+
Sbjct: 222 HKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLAD--YAFTSYS 279
Query: 203 PSVLALCLLNLEVETLK 219
PS+LA+C L L L+
Sbjct: 280 PSLLAICCLALADRMLR 296
>gi|4757930 cyclin B2 [Homo sapiens]
Length = 398
Score = 55.8 bits (133), Expect = 5e-08
Identities = 35/108 (32%), Positives = 58/108 (53%), Gaps = 2/108 (1%)
Query: 55 LRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVE 114
+R V+ L + + F ET + V I+DRFL + V K L +G+ + LLA++
Sbjct: 165 MRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKY-- 222
Query: 115 EDCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFL 162
E+ P+ D + I+ T+S I+ ME +I ++L +EL L+FL
Sbjct: 223 EEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFL 270
>gi|17318565 cyclin E2 [Homo sapiens]
Length = 404
Score = 53.5 bits (127), Expect = 3e-07
Identities = 33/114 (28%), Positives = 59/114 (51%), Gaps = 3/114 (2%)
Query: 53 PGLRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMK-VKPKHLSCIGVCSFLLAAR 111
P +R+ ++ L + + ETF LA + DRF+ K + L IG+ S +A++
Sbjct: 139 PQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASK 198
Query: 112 IVEEDCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLY 165
+ E+ P + ++ C+ DI RME II + L +EL T +++L+L+
Sbjct: 199 L--EEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLF 250
>gi|161377472 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 53.5 bits (127), Expect = 3e-07
Identities = 50/168 (29%), Positives = 75/168 (44%), Gaps = 16/168 (9%)
Query: 54 GLRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIV 113
G+R V+ L + + ET LAVN LDRFL+ M V L +G + LLA++
Sbjct: 198 GMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY- 256
Query: 114 EEDCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLY-HTIILCH 172
E+ P + + I+ T + +ME ++ + L ++L T FL Y +C
Sbjct: 257 -EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCV 315
Query: 173 TSER--KEILSLDKLEAQLKACNCRLIFSKAKPSVL---ALCLLNLEV 215
+E K + L LEA F K PS++ A CL N V
Sbjct: 316 RTENLAKYVAELSLLEAD--------PFLKYLPSLIAAAAFCLANYTV 355
>gi|161377470 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 53.5 bits (127), Expect = 3e-07
Identities = 50/168 (29%), Positives = 75/168 (44%), Gaps = 16/168 (9%)
Query: 54 GLRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIV 113
G+R V+ L + + ET LAVN LDRFL+ M V L +G + LLA++
Sbjct: 198 GMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY- 256
Query: 114 EEDCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLY-HTIILCH 172
E+ P + + I+ T + +ME ++ + L ++L T FL Y +C
Sbjct: 257 -EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCV 315
Query: 173 TSER--KEILSLDKLEAQLKACNCRLIFSKAKPSVL---ALCLLNLEV 215
+E K + L LEA F K PS++ A CL N V
Sbjct: 316 RTENLAKYVAELSLLEAD--------PFLKYLPSLIAAAAFCLANYTV 355
>gi|161377468 cyclin A1 isoform b [Homo sapiens]
Length = 464
Score = 53.5 bits (127), Expect = 3e-07
Identities = 50/168 (29%), Positives = 75/168 (44%), Gaps = 16/168 (9%)
Query: 54 GLRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIV 113
G+R V+ L + + ET LAVN LDRFL+ M V L +G + LLA++
Sbjct: 241 GMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY- 299
Query: 114 EEDCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLY-HTIILCH 172
E+ P + + I+ T + +ME ++ + L ++L T FL Y +C
Sbjct: 300 -EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCV 358
Query: 173 TSER--KEILSLDKLEAQLKACNCRLIFSKAKPSVL---ALCLLNLEV 215
+E K + L LEA F K PS++ A CL N V
Sbjct: 359 RTENLAKYVAELSLLEAD--------PFLKYLPSLIAAAAFCLANYTV 398
>gi|4502611 cyclin A1 isoform a [Homo sapiens]
Length = 465
Score = 53.5 bits (127), Expect = 3e-07
Identities = 50/168 (29%), Positives = 75/168 (44%), Gaps = 16/168 (9%)
Query: 54 GLRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIV 113
G+R V+ L + + ET LAVN LDRFL+ M V L +G + LLA++
Sbjct: 242 GMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY- 300
Query: 114 EEDCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLY-HTIILCH 172
E+ P + + I+ T + +ME ++ + L ++L T FL Y +C
Sbjct: 301 -EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCV 359
Query: 173 TSER--KEILSLDKLEAQLKACNCRLIFSKAKPSVL---ALCLLNLEV 215
+E K + L LEA F K PS++ A CL N V
Sbjct: 360 RTENLAKYVAELSLLEAD--------PFLKYLPSLIAAAAFCLANYTV 399
>gi|4502613 cyclin A [Homo sapiens]
Length = 432
Score = 51.2 bits (121), Expect = 1e-06
Identities = 41/146 (28%), Positives = 71/146 (48%), Gaps = 10/146 (6%)
Query: 21 LNVYL-EQEERFQPREKGLSLIEATPENDNTLCPGLRNAKVEDLRSLANFFGSCTETFVL 79
++ YL E E + +P+ + ++ P+ N++ R V+ L + + ET L
Sbjct: 182 IHTYLREMEVKCKPK---VGYMKKQPDITNSM----RAILVDWLVEVGEEYKLQNETLHL 234
Query: 80 AVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVIRISQCKCTASDIK 139
AVN +DRFL+ M V L +G + LLA++ E+ P + + I+ T +
Sbjct: 235 AVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKF--EEIYPPEVAEFVYITDDTYTKKQVL 292
Query: 140 RMEKIISEKLHYELEATTALNFLHLY 165
RME ++ + L ++L A T FL Y
Sbjct: 293 RMEHLVLKVLTFDLAAPTVNQFLTQY 318
>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
Length = 410
Score = 49.3 bits (116), Expect = 5e-06
Identities = 33/121 (27%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Query: 46 ENDNTLCPGLRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMK-VKPKHLSCIGVC 104
E L P +R ++ L + + ETF LA + DR++A + V L IG+
Sbjct: 135 EQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGIS 194
Query: 105 SFLLAARIVEEDCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHL 164
S +AA++ E+ P H ++ C+ +I ME +I + L + L T +++L++
Sbjct: 195 SLFIAAKL--EEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNV 252
Query: 165 Y 165
Y
Sbjct: 253 Y 253
>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
Length = 395
Score = 49.3 bits (116), Expect = 5e-06
Identities = 33/121 (27%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Query: 46 ENDNTLCPGLRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMK-VKPKHLSCIGVC 104
E L P +R ++ L + + ETF LA + DR++A + V L IG+
Sbjct: 120 EQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGIS 179
Query: 105 SFLLAARIVEEDCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHL 164
S +AA++ E+ P H ++ C+ +I ME +I + L + L T +++L++
Sbjct: 180 SLFIAAKL--EEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNV 237
Query: 165 Y 165
Y
Sbjct: 238 Y 238
>gi|4502617 cyclin D2 [Homo sapiens]
Length = 289
Score = 47.0 bits (110), Expect = 2e-05
Identities = 51/178 (28%), Positives = 82/178 (46%), Gaps = 25/178 (14%)
Query: 75 ETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVIRI-SQCKC 133
E F LA+N LDRFLA + HL +G LA+++ E P T + + I +
Sbjct: 75 EVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETS---PLTAEKLCIYTDNSI 131
Query: 134 TASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTSERKEILSLDKLEAQ--LKA 191
++ E ++ KL + L A T +F+ IL +++E LSL + AQ +
Sbjct: 132 KPQELLEWELVVLGKLKWNLAAVTPHDFIE----HILRKLPQQREKLSLIRKHAQTFIAL 187
Query: 192 CNCRLIFSKAKPSVL-------ALCLL--NLEVETLKSVELLEILLLVKKHSKINDTE 240
C F+ PS++ A+C L + EV +L L E+L +KI +T+
Sbjct: 188 CATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELL------AKITNTD 239
>gi|16950655 cyclin D1 [Homo sapiens]
Length = 295
Score = 45.4 bits (106), Expect = 7e-05
Identities = 36/134 (26%), Positives = 63/134 (47%), Gaps = 6/134 (4%)
Query: 75 ETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVIRI-SQCKC 133
E F LA+N LDRFL+L VK L +G +A+++ E IP T + + I +
Sbjct: 76 EVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKE---TIPLTAEKLCIYTDNSI 132
Query: 134 TASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTSERKEILSLDKLEAQLKACN 193
++ +ME ++ KL + L A T +F+ H + +E + + + + C
Sbjct: 133 RPEELLQMELLLVNKLKWNLAAMTPHDFIE--HFLSKMPEAEENKQIIRKHAQTFVALCA 190
Query: 194 CRLIFSKAKPSVLA 207
+ F PS++A
Sbjct: 191 TDVKFISNPPSMVA 204
>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
Length = 292
Score = 45.4 bits (106), Expect = 7e-05
Identities = 56/223 (25%), Positives = 96/223 (43%), Gaps = 24/223 (10%)
Query: 16 QLLG---LLNVYLEQEERFQPREKGLSLIEATPENDNTLCPGLRNAKVEDLRSLANFFGS 72
+LLG +L L EER+ PR ++ + P +R + +
Sbjct: 20 RLLGDQRVLQSLLRLEERYVPRASYFQCVQ------REIKPHMRKMLAYWMLEVCEEQRC 73
Query: 73 CTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVIRI-SQC 131
E F LA+N LDR+L+ + + L +G LLA+++ E P T + + I +
Sbjct: 74 EEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRE---TTPLTIEKLCIYTDH 130
Query: 132 KCTASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTSERKEILSLDKLEAQ--L 189
+ ++ E ++ KL ++L A A +FL IL S ++ +L K AQ L
Sbjct: 131 AVSPRQLRDWEVLVLGKLKWDLAAVIAHDFL----AFILHRLSLPRDRQALVKKHAQTFL 186
Query: 190 KACNCRLIFSKAKPSVLALCLLNLEVE-----TLKSVELLEIL 227
C F+ PS++A + V+ ++ EL E+L
Sbjct: 187 ALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELL 229
>gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo
sapiens]
Length = 307
Score = 43.1 bits (100), Expect = 4e-04
Identities = 26/101 (25%), Positives = 52/101 (51%), Gaps = 2/101 (1%)
Query: 53 PGLRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARI 112
P +R V+ L + + G +T LAV++LD +L+ +V+ L +GV +A ++
Sbjct: 105 PEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKM 164
Query: 113 VEEDCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYEL 153
E+C +P + +S + +++ R E+ I +L + L
Sbjct: 165 --EECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRL 203
>gi|14327896 cyclin B1 [Homo sapiens]
Length = 433
Score = 38.5 bits (88), Expect = 0.009
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Query: 75 ETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVIRISQCKCT 134
ET + V+I+DRF+ V K L +GV + +A++ E+ P D ++ T
Sbjct: 221 ETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKY--EEMYPPEIGDFAFVTDNTYT 278
Query: 135 ASDIKRMEKIISEKLHYELEATTALNFL 162
I++ME I L++ L L+FL
Sbjct: 279 KHQIRQMEMKILRALNFGLGRPLPLHFL 306
>gi|197276676 cyclin J isoform 3 [Homo sapiens]
Length = 371
Score = 37.7 bits (86), Expect = 0.015
Identities = 26/116 (22%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 55 LRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVE 114
LR + + ++N F C LAV +LD F+ + + L + + LLA++ E
Sbjct: 39 LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEE 98
Query: 115 EDCNIPSTHDVIRIS-----QCKCTASDIKRMEKIISEKLHYELEATTALNFLHLY 165
++ ++P + + T ++ ME ++ E + L TA +F+ Y
Sbjct: 99 KEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYY 154
>gi|197276674 cyclin J isoform 1 [Homo sapiens]
Length = 383
Score = 37.7 bits (86), Expect = 0.015
Identities = 26/116 (22%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 55 LRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVE 114
LR + + ++N F C LAV +LD F+ + + L + + LLA++ E
Sbjct: 39 LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEE 98
Query: 115 EDCNIPSTHDVIRIS-----QCKCTASDIKRMEKIISEKLHYELEATTALNFLHLY 165
++ ++P + + T ++ ME ++ E + L TA +F+ Y
Sbjct: 99 KEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYY 154
>gi|40254889 cyclin J isoform 2 [Homo sapiens]
Length = 372
Score = 37.7 bits (86), Expect = 0.015
Identities = 26/116 (22%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 55 LRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVE 114
LR + + ++N F C LAV +LD F+ + + L + + LLA++ E
Sbjct: 39 LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEE 98
Query: 115 EDCNIPSTHDVIRIS-----QCKCTASDIKRMEKIISEKLHYELEATTALNFLHLY 165
++ ++P + + T ++ ME ++ E + L TA +F+ Y
Sbjct: 99 KEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYY 154
>gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
Length = 211
Score = 37.4 bits (85), Expect = 0.020
Identities = 40/155 (25%), Positives = 71/155 (45%), Gaps = 15/155 (9%)
Query: 81 VNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVIRI-SQCKCTASDIK 139
+N LDR+L+ + + L +G LLA+++ E P T + + I + + ++
Sbjct: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRE---TTPLTIEKLCIYTDHAVSPRQLR 57
Query: 140 RMEKIISEKLHYELEATTALNFLHLYHTIILCHTSERKEILSLDKLEAQ--LKACNCRLI 197
E ++ KL ++L A A +FL IL S ++ +L K AQ L C
Sbjct: 58 DWEVLVLGKLKWDLAAVIAHDFL----AFILHRLSLPRDRQALVKKHAQTFLALCATDYT 113
Query: 198 FSKAKPSVLALCLLNLEVE-----TLKSVELLEIL 227
F+ PS++A + V+ ++ EL E+L
Sbjct: 114 FAMYPPSMIATGSIGAAVQGLGACSMSGDELTELL 148
>gi|208431829 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform b [Homo sapiens]
Length = 510
Score = 31.2 bits (69), Expect = 1.4
Identities = 19/79 (24%), Positives = 34/79 (43%), Gaps = 5/79 (6%)
Query: 257 SPECCKPDLKKLVWIVSRRTAQNLHNSYYSVPELPTIPEGGC-----FDESESEDSCEDM 311
+P PD+K+ + V +R A+ + + + + GC +D S+DS E
Sbjct: 244 APRFDLPDMKETKYTVDKRKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESS 303
Query: 312 SCGEESLSSSPPSDQECTF 330
E+ +S S +C F
Sbjct: 304 DYDPENSKNSSRSKTKCLF 322
>gi|24308527 stereocilin [Homo sapiens]
Length = 1775
Score = 30.4 bits (67), Expect = 2.4
Identities = 17/42 (40%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 287 VPELPTIPE--GGCFDESESEDSCEDMSCGEESLSSSPPSDQ 326
+P +P P+ GCF E+E+ + CGE SL + PPS+Q
Sbjct: 459 LPPVPLTPDIFWGCFLENET--LWAERLCGEASLQAVPPSNQ 498
>gi|157426885 organic cation transporter like 4 [Homo sapiens]
Length = 594
Score = 30.0 bits (66), Expect = 3.2
Identities = 29/106 (27%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 119 IPSTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTSERKE 178
+P D +R+ +C A+++K M ++ + L AT + FL +T L T R
Sbjct: 457 LPEGEDGLRLKWPRCPATELKSMTILVLMLREFSLAATVTVFFL---YTAELLPTVLRAT 513
Query: 179 ILSLDKLEAQLKACNCRLIFSKAKPSVLAL---CLLNLEVETLKSV 221
L L L + A I S+ PS+L + C+L + +L S+
Sbjct: 514 GLGLVSLASVAGAILSLTIISQT-PSLLPIFLCCVLAIVAFSLSSL 558
>gi|55741473 HECT, C2 and WW domain containing E3 ubiquitin protein
ligase 2 [Homo sapiens]
Length = 1572
Score = 29.6 bits (65), Expect = 4.1
Identities = 19/59 (32%), Positives = 25/59 (42%), Gaps = 6/59 (10%)
Query: 286 SVPELPTIPEGGCFDESESEDSCEDMSCGEESLSSSPPSDQECTFFFNFKVAQTLCFPS 344
SV E T PEG ES+ C D SC E + D C+ + + +T F S
Sbjct: 624 SVSEASTRPEG------ESDLECADSSCNESVTTQLSSVDTRCSSLESARFPETPAFSS 676
>gi|116517325 olfactory receptor, family 4, subfamily S, member 2
[Homo sapiens]
Length = 311
Score = 29.3 bits (64), Expect = 5.4
Identities = 16/34 (47%), Positives = 21/34 (61%), Gaps = 3/34 (8%)
Query: 68 NFFGSCTETFVLAVNILDRFLALMKVKPKHLSCI 101
+FFG CTE F+L V DR++A+ KP H I
Sbjct: 103 HFFG-CTEIFILTVMAYDRYVAI--CKPLHYMTI 133
>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 28.9 bits (63), Expect = 7.0
Identities = 33/157 (21%), Positives = 68/157 (43%), Gaps = 23/157 (14%)
Query: 112 IVEEDCNIPSTHDVIRISQCKCTASDIKRMEKIISE---------------KLHYELEAT 156
+++E+C + + ++R C ++++ K + + KL+ E+
Sbjct: 510 LMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEMITK 569
Query: 157 TA------LNFLHLYHTIILCHTSERKEILSLDKLEAQLKACNCRLIFSKAKPSVLALCL 210
TA LN L +T + + KE S KLEA++++ RL + +K S
Sbjct: 570 TAFWYQQELNDLKAENTRLNSELLKEKE--SKKKLEAEIESYQSRLAAAISKHSENVKTE 627
Query: 211 LNLEVETLKSVELLEILLLVKKHSKINDTEFFYWREL 247
NL++ ++ ++ E + + S+I D F +L
Sbjct: 628 RNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQL 664
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,501,394
Number of Sequences: 37866
Number of extensions: 586300
Number of successful extensions: 1627
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1597
Number of HSP's gapped (non-prelim): 37
length of query: 344
length of database: 18,247,518
effective HSP length: 103
effective length of query: 241
effective length of database: 14,347,320
effective search space: 3457704120
effective search space used: 3457704120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.