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Search of human proteins with 4757900
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4757900 calreticulin precursor [Homo sapiens]
(417 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4757900 calreticulin precursor [Homo sapiens] 883 0.0
gi|187608348 calreticulin 3 [Homo sapiens] 393 e-109
gi|66933005 calnexin precursor [Homo sapiens] 280 2e-75
gi|10716563 calnexin precursor [Homo sapiens] 280 2e-75
gi|194578888 calmegin [Homo sapiens] 256 3e-68
gi|4758004 calmegin [Homo sapiens] 256 3e-68
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 65 1e-10
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 65 1e-10
gi|17975763 myelin transcription factor 1 [Homo sapiens] 64 3e-10
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 60 5e-09
gi|215422388 death-domain associated protein isoform a [Homo sap... 60 5e-09
gi|215422366 death-domain associated protein isoform b [Homo sap... 60 5e-09
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 59 6e-09
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 58 1e-08
gi|4505999 protein phosphatase 1G [Homo sapiens] 57 2e-08
gi|29826282 protein phosphatase 1G [Homo sapiens] 57 2e-08
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 57 3e-08
gi|55956788 nucleolin [Homo sapiens] 56 5e-08
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 56 5e-08
gi|4504425 high-mobility group box 1 [Homo sapiens] 56 7e-08
gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo ... 56 7e-08
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 55 2e-07
gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens] 55 2e-07
gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens] 55 2e-07
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 55 2e-07
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 55 2e-07
gi|224586804 DNA-directed DNA polymerase epsilon 3 [Homo sapiens] 54 2e-07
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 54 3e-07
gi|13654270 LAS1-like [Homo sapiens] 54 3e-07
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens] 53 4e-07
>gi|4757900 calreticulin precursor [Homo sapiens]
Length = 417
Score = 883 bits (2282), Expect = 0.0
Identities = 417/417 (100%), Positives = 417/417 (100%)
Query: 1 MLLSVPLLLGLLGLAVAEPAVYFKEQFLDGDGWTSRWIESKHKSDFGKFVLSSGKFYGDE 60
MLLSVPLLLGLLGLAVAEPAVYFKEQFLDGDGWTSRWIESKHKSDFGKFVLSSGKFYGDE
Sbjct: 1 MLLSVPLLLGLLGLAVAEPAVYFKEQFLDGDGWTSRWIESKHKSDFGKFVLSSGKFYGDE 60
Query: 61 EKDKGLQTSQDARFYALSASFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQT 120
EKDKGLQTSQDARFYALSASFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQT
Sbjct: 61 EKDKGLQTSQDARFYALSASFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQT 120
Query: 121 DMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDN 180
DMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDN
Sbjct: 121 DMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDN 180
Query: 181 TYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPE 240
TYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPE
Sbjct: 181 TYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPE 240
Query: 241 HIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYS 300
HIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYS
Sbjct: 241 HIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYS 300
Query: 301 PDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDK 360
PDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDK
Sbjct: 301 PDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDK 360
Query: 361 QDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL 417
QDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL
Sbjct: 361 QDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL 417
>gi|187608348 calreticulin 3 [Homo sapiens]
Length = 384
Score = 393 bits (1010), Expect = e-109
Identities = 192/370 (51%), Positives = 254/370 (68%), Gaps = 21/370 (5%)
Query: 14 LAVAEPAVYFKEQFLDGDGWTSRWIESKHKSDFGKFVLSSGKFYGDEEKDKGLQTSQDAR 73
L VA VYF+E+FLDG+ W +RW++S + S FG F LSSGKFYG +EKDKGLQT+Q+ R
Sbjct: 14 LRVALATVYFQEEFLDGEHWRNRWLQSTNDSRFGHFRLSSGKFYGHKEKDKGLQTTQNGR 73
Query: 74 FYALSASFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQTDMHGDSEYNIMFG 133
FYA+SA F+PFSNKG+TLV+Q+TVKHEQ +DCGGGY+K+FP +DQ +++G S+Y IMFG
Sbjct: 74 FYAISARFKPFSNKGKTLVIQYTVKHEQKMDCGGGYIKVFPADIDQKNLNGKSQYYIMFG 133
Query: 134 PDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVES 193
PDICG KKVHVI ++K K K IRCK D FTHLYTLI+RPD +Y+VKID +ES
Sbjct: 134 PDICGFDIKKVHVILHFKNKYHENKKLIRCKVDGFTHLYTLILRPDLSYDVKIDGQSIES 193
Query: 194 GSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDW 253
GS+E DW+ KK P SK DW++ D+K +DW+K H D K DW
Sbjct: 194 GSIEYDWNLTSLKKETSPAESK--DWEQ------TKDNKAQDWEK--HFLDASTSKQSDW 243
Query: 254 DEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDPSIYAYDNFGV 313
+ ++DG+W P++Q P Y+ KP I +K W+H ++ N +Y + ++N G
Sbjct: 244 NGDLDGDWPAPMLQKPPYQDGLKPEGI----HKDVWLHRKMKNTDYLTQYDLSEFENIGA 299
Query: 314 LGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEED 373
+GL+LWQV+SGTIFDNFLIT+DE YA+ FG TWG TK E++M ++ +EE
Sbjct: 300 IGLELWQVRSGTIFDNFLITDDEEYADNFGKATWGETKGPEREM-------DAIQAKEEM 352
Query: 374 KKRKEEEEAE 383
KK +EEEE E
Sbjct: 353 KKAREEEEEE 362
>gi|66933005 calnexin precursor [Homo sapiens]
Length = 592
Score = 280 bits (715), Expect = 2e-75
Identities = 179/514 (34%), Positives = 249/514 (48%), Gaps = 120/514 (23%)
Query: 21 VYFKEQFLDGDGWTSRWIESKHKSDF--GKFVLSSGKFYGDEEK------DKGLQTSQDA 72
VYF + F G S WI SK K D + GK+ +E K DKGL A
Sbjct: 69 VYFADSF--DRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRA 126
Query: 73 RFYALSASF-EPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNS--LDQTDMHGDSEYN 129
+ +A+SA +PF + L+VQ+ V + I+CGG YVKL + L+ H + Y
Sbjct: 127 KHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYT 186
Query: 130 IMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCK----------DDEFTHLYTLIVRPD 179
IMFGPD CG K +H IF +K I ++ K D+ THLYTLI+ PD
Sbjct: 187 IMFGPDKCGEDYK-LHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTLILNPD 245
Query: 180 NTYEVKIDNSQVESGSLEDDWD--FLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWD 237
N++E+ +D S V SG+L +D P ++I+DP+ KPEDWDER KI DP KP+DWD
Sbjct: 246 NSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVKPDDWD 305
Query: 238 K---------------------PEHIPDPDAKKPEDWDEEMDGEWEPP------------ 264
+ PE++PDPDA+KPEDWDE+MDGEWE P
Sbjct: 306 EDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRCESAPG 365
Query: 265 -------VIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDPSIYAYDNFGVLGLD 317
VI NP YKG+WKP IDNP Y+G W +I NP++ D + F +GL+
Sbjct: 366 CGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLE 425
Query: 318 LWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTK----------------AAEK------ 355
LW + S FDNF+I D +++ N+ WG+ K AAE+
Sbjct: 426 LWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWV 485
Query: 356 ---------------------------QMKDKQDEEQRLKEEEEDKKRK-----EEEEAE 383
+ K + +KEEEE+K+ + EEEE E
Sbjct: 486 VYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGE 545
Query: 384 DKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL 417
+K +++ K + EED ++EE+ P +DE+
Sbjct: 546 EKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579
>gi|10716563 calnexin precursor [Homo sapiens]
Length = 592
Score = 280 bits (715), Expect = 2e-75
Identities = 179/514 (34%), Positives = 249/514 (48%), Gaps = 120/514 (23%)
Query: 21 VYFKEQFLDGDGWTSRWIESKHKSDF--GKFVLSSGKFYGDEEK------DKGLQTSQDA 72
VYF + F G S WI SK K D + GK+ +E K DKGL A
Sbjct: 69 VYFADSF--DRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRA 126
Query: 73 RFYALSASF-EPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNS--LDQTDMHGDSEYN 129
+ +A+SA +PF + L+VQ+ V + I+CGG YVKL + L+ H + Y
Sbjct: 127 KHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYT 186
Query: 130 IMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCK----------DDEFTHLYTLIVRPD 179
IMFGPD CG K +H IF +K I ++ K D+ THLYTLI+ PD
Sbjct: 187 IMFGPDKCGEDYK-LHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTLILNPD 245
Query: 180 NTYEVKIDNSQVESGSLEDDWD--FLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWD 237
N++E+ +D S V SG+L +D P ++I+DP+ KPEDWDER KI DP KP+DWD
Sbjct: 246 NSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVKPDDWD 305
Query: 238 K---------------------PEHIPDPDAKKPEDWDEEMDGEWEPP------------ 264
+ PE++PDPDA+KPEDWDE+MDGEWE P
Sbjct: 306 EDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRCESAPG 365
Query: 265 -------VIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDPSIYAYDNFGVLGLD 317
VI NP YKG+WKP IDNP Y+G W +I NP++ D + F +GL+
Sbjct: 366 CGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLE 425
Query: 318 LWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTK----------------AAEK------ 355
LW + S FDNF+I D +++ N+ WG+ K AAE+
Sbjct: 426 LWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWV 485
Query: 356 ---------------------------QMKDKQDEEQRLKEEEEDKKRK-----EEEEAE 383
+ K + +KEEEE+K+ + EEEE E
Sbjct: 486 VYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGE 545
Query: 384 DKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL 417
+K +++ K + EED ++EE+ P +DE+
Sbjct: 546 EKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579
>gi|194578888 calmegin [Homo sapiens]
Length = 610
Score = 256 bits (654), Expect = 3e-68
Identities = 172/507 (33%), Positives = 250/507 (49%), Gaps = 123/507 (24%)
Query: 21 VYFKEQFLDGDGWTSRWIESKHKSDFGKFVLS--SGKFYGDEEK------DKGLQTSQDA 72
VYF E F G + W+ SK K D +S G++ +E K D+GL A
Sbjct: 60 VYFAETF--DSGRLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDRGLVLKSRA 117
Query: 73 RFYALSASF-EPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQT--DMHGDSEYN 129
+ +A+SA +PF + L+VQ+ V + IDCGG Y+KL ++ D + + + Y
Sbjct: 118 KHHAISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILENFYDKTSYI 177
Query: 130 IMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKD----------DEFTHLYTLIVRPD 179
IMFGPD CG K +H IF +K + ++ K D THLYTL++ PD
Sbjct: 178 IMFGPDKCGEDYK-LHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPD 236
Query: 180 NTYEVKIDNSQVESGSLEDDW--DFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWD 237
+T+EV +D + V GSL +D PPK+I+DP+ KPE+WDERAKI DP+ KPEDWD
Sbjct: 237 DTFEVLVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWD 296
Query: 238 K---------------------PEHIPDPDAKKPEDWDEEMDGEWE-------------- 262
+ P+ IPDP+A+KP+DW+E+ DGEWE
Sbjct: 297 ESEPAQIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNPACRIGCG 356
Query: 263 ---PPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDPSIYAYDNFGVLGLDLW 319
PP+I NP+YKG W+P +DNP+Y+G W +I NP+Y D + +F LGL+LW
Sbjct: 357 EWKPPMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELW 416
Query: 320 QVKSGTIFDNFLITNDEAYAEEFGNETW------------GVTK----AAE--------- 354
+ S FDNF+I +++ A+ + + W GV K AAE
Sbjct: 417 SMTSDIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAEGHPWLWLIY 476
Query: 355 ------------------KQMKDKQDEEQR------------LKEEEEDKKRKEEE---- 380
K K +D E + L++EE+++K E+
Sbjct: 477 LVTAGVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDL 536
Query: 381 EAEDKEDDEDKDEDEEDEEDKEEDEEE 407
E E K++D + E EE+ E +E+ EEE
Sbjct: 537 EEEKKQNDGEMLEKEEESEPEEKSEEE 563
Score = 36.6 bits (83), Expect = 0.043
Identities = 21/73 (28%), Positives = 41/73 (56%), Gaps = 1/73 (1%)
Query: 345 ETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEED 404
+T GV + EK+ K ++ L+EE++ + E+ E+ E +E +E+ E E +EE
Sbjct: 514 QTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEES 573
Query: 405 EEEDVPGQAKDEL 417
+ + G ++DE+
Sbjct: 574 NQSNKSG-SEDEM 585
Score = 34.3 bits (77), Expect = 0.22
Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 4/70 (5%)
Query: 340 EEFGNETWGVTKAAEKQMKDKQDEEQRL-KEEEEDKKRKEEEEAEDKEDDEDKDEDEE-- 396
+E E + K + + + KQ++ + L KEEE + + K EEE E E E+ ++ +
Sbjct: 521 QEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSG 580
Query: 397 -DEEDKEEDE 405
++E KE DE
Sbjct: 581 SEDEMKEADE 590
>gi|4758004 calmegin [Homo sapiens]
Length = 610
Score = 256 bits (654), Expect = 3e-68
Identities = 172/507 (33%), Positives = 250/507 (49%), Gaps = 123/507 (24%)
Query: 21 VYFKEQFLDGDGWTSRWIESKHKSDFGKFVLS--SGKFYGDEEK------DKGLQTSQDA 72
VYF E F G + W+ SK K D +S G++ +E K D+GL A
Sbjct: 60 VYFAETF--DSGRLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDRGLVLKSRA 117
Query: 73 RFYALSASF-EPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQT--DMHGDSEYN 129
+ +A+SA +PF + L+VQ+ V + IDCGG Y+KL ++ D + + + Y
Sbjct: 118 KHHAISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILENFYDKTSYI 177
Query: 130 IMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKD----------DEFTHLYTLIVRPD 179
IMFGPD CG K +H IF +K + ++ K D THLYTL++ PD
Sbjct: 178 IMFGPDKCGEDYK-LHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPD 236
Query: 180 NTYEVKIDNSQVESGSLEDDW--DFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWD 237
+T+EV +D + V GSL +D PPK+I+DP+ KPE+WDERAKI DP+ KPEDWD
Sbjct: 237 DTFEVLVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWD 296
Query: 238 K---------------------PEHIPDPDAKKPEDWDEEMDGEWE-------------- 262
+ P+ IPDP+A+KP+DW+E+ DGEWE
Sbjct: 297 ESEPAQIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNPACRIGCG 356
Query: 263 ---PPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDPSIYAYDNFGVLGLDLW 319
PP+I NP+YKG W+P +DNP+Y+G W +I NP+Y D + +F LGL+LW
Sbjct: 357 EWKPPMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELW 416
Query: 320 QVKSGTIFDNFLITNDEAYAEEFGNETW------------GVTK----AAE--------- 354
+ S FDNF+I +++ A+ + + W GV K AAE
Sbjct: 417 SMTSDIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAEGHPWLWLIY 476
Query: 355 ------------------KQMKDKQDEEQR------------LKEEEEDKKRKEEE---- 380
K K +D E + L++EE+++K E+
Sbjct: 477 LVTAGVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDL 536
Query: 381 EAEDKEDDEDKDEDEEDEEDKEEDEEE 407
E E K++D + E EE+ E +E+ EEE
Sbjct: 537 EEEKKQNDGEMLEKEEESEPEEKSEEE 563
Score = 36.6 bits (83), Expect = 0.043
Identities = 21/73 (28%), Positives = 41/73 (56%), Gaps = 1/73 (1%)
Query: 345 ETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEED 404
+T GV + EK+ K ++ L+EE++ + E+ E+ E +E +E+ E E +EE
Sbjct: 514 QTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEES 573
Query: 405 EEEDVPGQAKDEL 417
+ + G ++DE+
Sbjct: 574 NQSNKSG-SEDEM 585
Score = 34.3 bits (77), Expect = 0.22
Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 4/70 (5%)
Query: 340 EEFGNETWGVTKAAEKQMKDKQDEEQRL-KEEEEDKKRKEEEEAEDKEDDEDKDEDEE-- 396
+E E + K + + + KQ++ + L KEEE + + K EEE E E E+ ++ +
Sbjct: 521 QEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSG 580
Query: 397 -DEEDKEEDE 405
++E KE DE
Sbjct: 581 SEDEMKEADE 590
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 64.7 bits (156), Expect = 1e-10
Identities = 30/85 (35%), Positives = 60/85 (70%), Gaps = 1/85 (1%)
Query: 333 TNDEAYAEEFGNE-TWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDK 391
+ +E +EE+G++ G + ++++Q + ++EE+ ++E+ E+ + EE+ ED+E DED
Sbjct: 170 SKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDG 229
Query: 392 DEDEEDEEDKEEDEEEDVPGQAKDE 416
+E+EE+EE++EE+EEE+ +DE
Sbjct: 230 EEEEEEEEEEEEEEEEEEEEYEQDE 254
Score = 56.2 bits (134), Expect = 5e-08
Identities = 24/76 (31%), Positives = 49/76 (64%)
Query: 333 TNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKD 392
T ++E GN T + E+ +++ ++ E+ +E+EE + EEEE E++E++E+++
Sbjct: 185 TGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEE 244
Query: 393 EDEEDEEDKEEDEEED 408
E+EE+ E E D++E+
Sbjct: 245 EEEEEYEQDERDQKEE 260
Score = 47.0 bits (110), Expect = 3e-05
Identities = 24/70 (34%), Positives = 42/70 (60%)
Query: 334 NDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDE 393
N+E EE E V + AE+ + +D E+ +EEEE+++ +EEEE E ++D+ D+ E
Sbjct: 200 NEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKE 259
Query: 394 DEEDEEDKEE 403
+ D + + E
Sbjct: 260 EGNDYDTRSE 269
Score = 36.2 bits (82), Expect = 0.057
Identities = 19/71 (26%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Query: 339 AEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDK-DEDEED 397
+E G E + + K++ + E+ + E +E+ + E++E+ +ED E+
Sbjct: 152 SERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEE 211
Query: 398 EEDKEEDEEED 408
+E+ EED EED
Sbjct: 212 DEEVEEDAEED 222
Score = 35.0 bits (79), Expect = 0.13
Identities = 30/104 (28%), Positives = 39/104 (37%), Gaps = 41/104 (39%)
Query: 354 EKQMKDKQDEEQRLKEEEED-----------------KKRKEEEEAEDKEDD-------- 388
EK K+D E+R K D + KEE +E+ D
Sbjct: 131 EKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGS 190
Query: 389 ----------------EDKDEDEEDEEDKEEDEEEDVPGQAKDE 416
ED +EDEE EED EEDEE D G+ ++E
Sbjct: 191 SDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEE 234
Score = 32.7 bits (73), Expect = 0.63
Identities = 25/111 (22%), Positives = 49/111 (44%), Gaps = 7/111 (6%)
Query: 293 EIDNPEYSPDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKA 352
E+++ EY D + + G + + G D + DE E+ +
Sbjct: 173 EVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEED---VEEDEEVEEDAEEDEEVDEDG 229
Query: 353 AEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEE 403
E++ +++++EE+ +EEEE E++E + KE+ D D E + E
Sbjct: 230 EEEEEEEEEEEEEEEEEEEE----YEQDERDQKEEGNDYDTRSEASDSGSE 276
Score = 32.3 bits (72), Expect = 0.82
Identities = 18/75 (24%), Positives = 34/75 (45%)
Query: 343 GNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKE 402
G+E G+ + +E+ EE + D++ + ++E+E EED E
Sbjct: 151 GSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVE 210
Query: 403 EDEEEDVPGQAKDEL 417
EDEE + + +E+
Sbjct: 211 EDEEVEEDAEEDEEV 225
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 64.7 bits (156), Expect = 1e-10
Identities = 30/85 (35%), Positives = 60/85 (70%), Gaps = 1/85 (1%)
Query: 333 TNDEAYAEEFGNE-TWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDK 391
+ +E +EE+G++ G + ++++Q + ++EE+ ++E+ E+ + EE+ ED+E DED
Sbjct: 170 SKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDG 229
Query: 392 DEDEEDEEDKEEDEEEDVPGQAKDE 416
+E+EE+EE++EE+EEE+ +DE
Sbjct: 230 EEEEEEEEEEEEEEEEEEEEYEQDE 254
Score = 56.2 bits (134), Expect = 5e-08
Identities = 24/76 (31%), Positives = 49/76 (64%)
Query: 333 TNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKD 392
T ++E GN T + E+ +++ ++ E+ +E+EE + EEEE E++E++E+++
Sbjct: 185 TGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEE 244
Query: 393 EDEEDEEDKEEDEEED 408
E+EE+ E E D++E+
Sbjct: 245 EEEEEYEQDERDQKEE 260
Score = 47.0 bits (110), Expect = 3e-05
Identities = 24/70 (34%), Positives = 42/70 (60%)
Query: 334 NDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDE 393
N+E EE E V + AE+ + +D E+ +EEEE+++ +EEEE E ++D+ D+ E
Sbjct: 200 NEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKE 259
Query: 394 DEEDEEDKEE 403
+ D + + E
Sbjct: 260 EGNDYDTRSE 269
Score = 36.2 bits (82), Expect = 0.057
Identities = 19/71 (26%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Query: 339 AEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDK-DEDEED 397
+E G E + + K++ + E+ + E +E+ + E++E+ +ED E+
Sbjct: 152 SERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEE 211
Query: 398 EEDKEEDEEED 408
+E+ EED EED
Sbjct: 212 DEEVEEDAEED 222
Score = 35.0 bits (79), Expect = 0.13
Identities = 30/104 (28%), Positives = 39/104 (37%), Gaps = 41/104 (39%)
Query: 354 EKQMKDKQDEEQRLKEEEED-----------------KKRKEEEEAEDKEDD-------- 388
EK K+D E+R K D + KEE +E+ D
Sbjct: 131 EKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGS 190
Query: 389 ----------------EDKDEDEEDEEDKEEDEEEDVPGQAKDE 416
ED +EDEE EED EEDEE D G+ ++E
Sbjct: 191 SDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEE 234
Score = 32.7 bits (73), Expect = 0.63
Identities = 25/111 (22%), Positives = 49/111 (44%), Gaps = 7/111 (6%)
Query: 293 EIDNPEYSPDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKA 352
E+++ EY D + + G + + G D + DE E+ +
Sbjct: 173 EVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEED---VEEDEEVEEDAEEDEEVDEDG 229
Query: 353 AEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEE 403
E++ +++++EE+ +EEEE E++E + KE+ D D E + E
Sbjct: 230 EEEEEEEEEEEEEEEEEEEE----YEQDERDQKEEGNDYDTRSEASDSGSE 276
Score = 32.3 bits (72), Expect = 0.82
Identities = 18/75 (24%), Positives = 34/75 (45%)
Query: 343 GNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKE 402
G+E G+ + +E+ EE + D++ + ++E+E EED E
Sbjct: 151 GSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVE 210
Query: 403 EDEEEDVPGQAKDEL 417
EDEE + + +E+
Sbjct: 211 EDEEVEEDAEEDEEV 225
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 63.9 bits (154), Expect = 3e-10
Identities = 25/52 (48%), Positives = 45/52 (86%)
Query: 359 DKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVP 410
+++DEE+ +EEEE++ +EEEE E++E++E+++E+EE+EE++EE+EEE P
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309
Score = 60.5 bits (145), Expect = 3e-09
Identities = 26/62 (41%), Positives = 49/62 (79%), Gaps = 5/62 (8%)
Query: 352 AAEKQMKDK-----QDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEE 406
A+E+ K K ++E++ +EEEE+++ EEEE E++E++E+++E+EE+EE++EE+EE
Sbjct: 244 ASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303
Query: 407 ED 408
E+
Sbjct: 304 EE 305
Score = 59.7 bits (143), Expect = 5e-09
Identities = 25/66 (37%), Positives = 48/66 (72%)
Query: 340 EEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEE 399
E+ +E K ++ ++EE+ +EEEED++ +EEEE E++E++E+++E+EE+EE
Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300
Query: 400 DKEEDE 405
++EE+E
Sbjct: 301 EEEEEE 306
Score = 59.3 bits (142), Expect = 6e-09
Identities = 27/74 (36%), Positives = 53/74 (71%), Gaps = 3/74 (4%)
Query: 336 EAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDE 395
E A E ++ G+ E+ D+++EE+ +EEE++++ +EEEE E++E++E+++E+E
Sbjct: 241 EDAASEESSKQKGILSHEEE---DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297
Query: 396 EDEEDKEEDEEEDV 409
E+EE++EE+ DV
Sbjct: 298 EEEEEEEEEAAPDV 311
Score = 58.2 bits (139), Expect = 1e-08
Identities = 25/64 (39%), Positives = 47/64 (73%)
Query: 353 AEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQ 412
A + KQ +EE+E+++ +EEEE ED+E++E+++E+EE+EE++EE+EEE+ +
Sbjct: 243 AASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEE 302
Query: 413 AKDE 416
++E
Sbjct: 303 EEEE 306
Score = 57.0 bits (136), Expect = 3e-08
Identities = 22/66 (33%), Positives = 48/66 (72%)
Query: 351 KAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVP 410
++ E ++ +++ + EE+ + +EEEE E++ED+E+++E+EE+EE++EE+EEE+
Sbjct: 238 QSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297
Query: 411 GQAKDE 416
+ ++E
Sbjct: 298 EEEEEE 303
Score = 56.2 bits (134), Expect = 5e-08
Identities = 23/70 (32%), Positives = 50/70 (71%)
Query: 335 DEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDED 394
++A +EE + ++ E + +++++EE+ EEEE+++ +EEEE E++E++E+++E+
Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300
Query: 395 EEDEEDKEED 404
EE+EE+ D
Sbjct: 301 EEEEEEAAPD 310
Score = 50.8 bits (120), Expect = 2e-06
Identities = 20/55 (36%), Positives = 44/55 (80%)
Query: 354 EKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEED 408
E++ +++++EE+ +EEEE+++ +EEEE E++E++E+++E+EE+E + +ED
Sbjct: 262 EEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQED 316
Score = 45.8 bits (107), Expect = 7e-05
Identities = 21/76 (27%), Positives = 45/76 (59%)
Query: 341 EFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEED 400
E E VT + + + E+ +E + K EE +++E++E+++E+E++EE+
Sbjct: 219 EDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEE 278
Query: 401 KEEDEEEDVPGQAKDE 416
+EE+EEE+ + ++E
Sbjct: 279 EEEEEEEEEEEEEEEE 294
Score = 45.8 bits (107), Expect = 7e-05
Identities = 18/64 (28%), Positives = 44/64 (68%)
Query: 354 EKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQA 413
E++ ++++++E+ +EEEE+++ +EEEE E++E++E+++E+E + +++ Q
Sbjct: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQK 324
Query: 414 KDEL 417
EL
Sbjct: 325 APEL 328
Score = 38.5 bits (88), Expect = 0.011
Identities = 21/74 (28%), Positives = 41/74 (55%), Gaps = 3/74 (4%)
Query: 337 AYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEE 396
++ EE E + E + +++++EE+ +EEEE++ EEEE E++E++E+ D
Sbjct: 256 SHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEE---EEEEEEEEEEEEEAAPDVI 312
Query: 397 DEEDKEEDEEEDVP 410
+ED + P
Sbjct: 313 FQEDTSHTSAQKAP 326
Score = 37.0 bits (84), Expect = 0.033
Identities = 21/76 (27%), Positives = 37/76 (48%)
Query: 335 DEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDED 394
DE EE E + E++ +++++EE+ +EEEE+++ +EEE A D ED
Sbjct: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHT 320
Query: 395 EEDEEDKEEDEEEDVP 410
+ + E P
Sbjct: 321 SAQKAPELRGPESPSP 336
Score = 36.6 bits (83), Expect = 0.043
Identities = 20/63 (31%), Positives = 36/63 (57%)
Query: 332 ITNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDK 391
I + E EE E + E++ +++++EE+ +EEEE+++ +EEEE E+ D
Sbjct: 254 ILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIF 313
Query: 392 DED 394
ED
Sbjct: 314 QED 316
Score = 35.8 bits (81), Expect = 0.074
Identities = 17/57 (29%), Positives = 35/57 (61%)
Query: 331 LITNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKED 387
+++++E EE E E++ +++++EE+ +EEEE+++ +EEEE E D
Sbjct: 254 ILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPD 310
Score = 33.5 bits (75), Expect = 0.37
Identities = 17/61 (27%), Positives = 33/61 (54%)
Query: 356 QMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKD 415
Q +D ++ + E +D + E+A +E + K +EED+EE+EEE+ + ++
Sbjct: 217 QPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEE 276
Query: 416 E 416
E
Sbjct: 277 E 277
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 59.7 bits (143), Expect = 5e-09
Identities = 29/73 (39%), Positives = 46/73 (63%), Gaps = 2/73 (2%)
Query: 343 GNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKE 402
G + G A+ + D+ DEE EEEE+++ +EEEEA D E++ED ++ +E +ED E
Sbjct: 421 GMASQGCPSASRAETDDEDDEES--DEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDE 478
Query: 403 EDEEEDVPGQAKD 415
E++EE+ KD
Sbjct: 479 EEDEEEEAAAGKD 491
Score = 38.1 bits (87), Expect = 0.015
Identities = 13/34 (38%), Positives = 27/34 (79%)
Query: 384 DKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL 417
+ +D++D++ DEE+EE++EE+EEE + +++L
Sbjct: 434 ETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDL 467
Score = 34.3 bits (77), Expect = 0.22
Identities = 13/35 (37%), Positives = 25/35 (71%)
Query: 382 AEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDE 416
A E D++ DE+ ++EE++EE+EEE+ +++E
Sbjct: 430 ASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEE 464
Score = 31.6 bits (70), Expect = 1.4
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 12/71 (16%)
Query: 335 DEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDED 394
D+ EE E + E++ D EEEED E+ E +EDDE++DE+
Sbjct: 436 DDEDDEESDEEEEEEEEEEEEEATD--------SEEEEDL----EQMQEGQEDDEEEDEE 483
Query: 395 EEDEEDKEEDE 405
EE K+ D+
Sbjct: 484 EEAAAGKDGDK 494
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 59.7 bits (143), Expect = 5e-09
Identities = 29/73 (39%), Positives = 46/73 (63%), Gaps = 2/73 (2%)
Query: 343 GNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKE 402
G + G A+ + D+ DEE EEEE+++ +EEEEA D E++ED ++ +E +ED E
Sbjct: 421 GMASQGCPSASRAETDDEDDEES--DEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDE 478
Query: 403 EDEEEDVPGQAKD 415
E++EE+ KD
Sbjct: 479 EEDEEEEAAAGKD 491
Score = 38.1 bits (87), Expect = 0.015
Identities = 13/34 (38%), Positives = 27/34 (79%)
Query: 384 DKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL 417
+ +D++D++ DEE+EE++EE+EEE + +++L
Sbjct: 434 ETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDL 467
Score = 34.3 bits (77), Expect = 0.22
Identities = 13/35 (37%), Positives = 25/35 (71%)
Query: 382 AEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDE 416
A E D++ DE+ ++EE++EE+EEE+ +++E
Sbjct: 430 ASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEE 464
Score = 31.6 bits (70), Expect = 1.4
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 12/71 (16%)
Query: 335 DEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDED 394
D+ EE E + E++ D EEEED E+ E +EDDE++DE+
Sbjct: 436 DDEDDEESDEEEEEEEEEEEEEATD--------SEEEEDL----EQMQEGQEDDEEEDEE 483
Query: 395 EEDEEDKEEDE 405
EE K+ D+
Sbjct: 484 EEAAAGKDGDK 494
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 59.7 bits (143), Expect = 5e-09
Identities = 29/73 (39%), Positives = 46/73 (63%), Gaps = 2/73 (2%)
Query: 343 GNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKE 402
G + G A+ + D+ DEE EEEE+++ +EEEEA D E++ED ++ +E +ED E
Sbjct: 433 GMASQGCPSASRAETDDEDDEES--DEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDE 490
Query: 403 EDEEEDVPGQAKD 415
E++EE+ KD
Sbjct: 491 EEDEEEEAAAGKD 503
Score = 38.1 bits (87), Expect = 0.015
Identities = 13/34 (38%), Positives = 27/34 (79%)
Query: 384 DKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL 417
+ +D++D++ DEE+EE++EE+EEE + +++L
Sbjct: 446 ETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDL 479
Score = 34.3 bits (77), Expect = 0.22
Identities = 13/35 (37%), Positives = 25/35 (71%)
Query: 382 AEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDE 416
A E D++ DE+ ++EE++EE+EEE+ +++E
Sbjct: 442 ASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEE 476
Score = 31.6 bits (70), Expect = 1.4
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 12/71 (16%)
Query: 335 DEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDED 394
D+ EE E + E++ D EEEED E+ E +EDDE++DE+
Sbjct: 448 DDEDDEESDEEEEEEEEEEEEEATD--------SEEEEDL----EQMQEGQEDDEEEDEE 495
Query: 395 EEDEEDKEEDE 405
EE K+ D+
Sbjct: 496 EEAAAGKDGDK 506
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 59.3 bits (142), Expect = 6e-09
Identities = 24/58 (41%), Positives = 45/58 (77%)
Query: 351 KAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEED 408
K EK+ K K E ++ KE+EE++K+++ + + KE++E ++E+EE+EE+KEE+E+E+
Sbjct: 36 KRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEE 93
Score = 54.7 bits (130), Expect = 2e-07
Identities = 28/79 (35%), Positives = 50/79 (63%), Gaps = 7/79 (8%)
Query: 345 ETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDK-------DEDEED 397
ET + EK+ K K+ +++ KE+E+ KK KE E+ ++KE++E K ++EE+
Sbjct: 15 ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEE 74
Query: 398 EEDKEEDEEEDVPGQAKDE 416
E++EE+EEE+ + K+E
Sbjct: 75 REEEEEEEEEEKEEEEKEE 93
Score = 52.8 bits (125), Expect = 6e-07
Identities = 31/89 (34%), Positives = 54/89 (60%), Gaps = 8/89 (8%)
Query: 333 TNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDK------- 385
T + EE E K EK+ K+K+ E+++ K+ +E +KRKE+EE E K
Sbjct: 10 TEETEETEETEEEEEKEGKRKEKR-KEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKK 68
Query: 386 EDDEDKDEDEEDEEDKEEDEEEDVPGQAK 414
+ +E++ E+EE+EE++E++EEE G+ +
Sbjct: 69 KKEEEEREEEEEEEEEEKEEEEKEEGRRR 97
Score = 51.6 bits (122), Expect = 1e-06
Identities = 26/68 (38%), Positives = 46/68 (67%), Gaps = 11/68 (16%)
Query: 350 TKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDE----------E 399
TK EK+ K+K++EE++ K + + KK +EE E E++E++E+K+E+E++E
Sbjct: 46 TKETEKR-KEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRR 104
Query: 400 DKEEDEEE 407
KEE+EE+
Sbjct: 105 RKEEEEEK 112
Score = 47.4 bits (111), Expect = 2e-05
Identities = 23/72 (31%), Positives = 48/72 (66%), Gaps = 4/72 (5%)
Query: 340 EEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEE 399
+E +T K EK+ ++K+ + +R K++EE+++ +EEEE E+++++E+K+E ++
Sbjct: 40 KEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKK 99
Query: 400 DK----EEDEEE 407
K +E+EEE
Sbjct: 100 KKKRRRKEEEEE 111
Score = 44.7 bits (104), Expect = 2e-04
Identities = 20/56 (35%), Positives = 38/56 (67%)
Query: 351 KAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEE 406
K +++ K K++EE+R +EEEE+++ KEEEE E+ + K + EE++E+ ++
Sbjct: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115
Score = 35.4 bits (80), Expect = 0.097
Identities = 16/55 (29%), Positives = 36/55 (65%), Gaps = 3/55 (5%)
Query: 351 KAAEKQMKDKQDEEQRLKEEEED---KKRKEEEEAEDKEDDEDKDEDEEDEEDKE 402
K E++ +++++EE+ KEEEE ++RK++++ KE++E+K + + K+
Sbjct: 69 KKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 30.8 bits (68), Expect = 2.4
Identities = 12/54 (22%), Positives = 35/54 (64%)
Query: 363 EEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDE 416
++++ K+E E+ + EE E E++++ + K++ +E ++KE+ ++ + K++
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEK 55
Score = 30.4 bits (67), Expect = 3.1
Identities = 13/57 (22%), Positives = 35/57 (61%)
Query: 360 KQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDE 416
K+ ++++ + EE ++ + EEE E + ++K +++ E++K++ +E + K+E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE 57
Score = 30.4 bits (67), Expect = 3.1
Identities = 16/51 (31%), Positives = 28/51 (54%)
Query: 335 DEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDK 385
+E EE E + E+ + K+ +++R KEEEE+KK+K + + K
Sbjct: 73 EEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 58.2 bits (139), Expect = 1e-08
Identities = 25/50 (50%), Positives = 40/50 (80%)
Query: 368 KEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL 417
KEEEE+++ EEEE ED+E++E+++E+EE+EE++EE+EEE A E+
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEV 781
Score = 51.6 bits (122), Expect = 1e-06
Identities = 20/46 (43%), Positives = 39/46 (84%)
Query: 361 QDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEE 406
Q + +EEEE+++ +EEEE +++E++E+++E+EE+EE++EE+EE
Sbjct: 726 QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 50.1 bits (118), Expect = 4e-06
Identities = 19/46 (41%), Positives = 38/46 (82%)
Query: 354 EKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEE 399
+ Q K++EE+ ++EEE+++ +EEEE E++E++E+++E+EE+EE
Sbjct: 726 QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 49.3 bits (116), Expect = 6e-06
Identities = 18/42 (42%), Positives = 36/42 (85%)
Query: 367 LKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEED 408
++ + K+ +EEEE +++E++ED++E+EE+EE++EE+EEE+
Sbjct: 725 VQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEE 766
Score = 42.4 bits (98), Expect = 8e-04
Identities = 16/47 (34%), Positives = 36/47 (76%)
Query: 349 VTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDE 395
V A + +++++EE +EEE++++ +EEEE E++E++E+++E+E
Sbjct: 725 VQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 42.0 bits (97), Expect = 0.001
Identities = 16/38 (42%), Positives = 30/38 (78%)
Query: 379 EEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDE 416
+ +A KE++E+++EDEE+EE+ EE+EEE+ + ++E
Sbjct: 726 QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEE 763
Score = 39.3 bits (90), Expect = 0.007
Identities = 13/38 (34%), Positives = 31/38 (81%)
Query: 379 EEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDE 416
+ +++E++E++DE+EE+E+++EE+EEE+ + ++E
Sbjct: 728 QANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEE 765
Score = 38.9 bits (89), Expect = 0.009
Identities = 17/62 (27%), Positives = 37/62 (59%)
Query: 327 FDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKE 386
F + L+T + + G + E++ ++++EE +EEEE+++ +EEEE E++E
Sbjct: 710 FSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEE 769
Query: 387 DD 388
++
Sbjct: 770 EE 771
Score = 32.0 bits (71), Expect = 1.1
Identities = 12/29 (41%), Positives = 24/29 (82%)
Query: 354 EKQMKDKQDEEQRLKEEEEDKKRKEEEEA 382
E++ ++++EE+ +EEEE+++ +EEEEA
Sbjct: 744 EEEEDEEEEEEEEEEEEEEEEEEEEEEEA 772
Score = 30.0 bits (66), Expect = 4.1
Identities = 11/29 (37%), Positives = 24/29 (82%)
Query: 354 EKQMKDKQDEEQRLKEEEEDKKRKEEEEA 382
E++ +++++EE+ +EEEE+++ +EEE A
Sbjct: 745 EEEDEEEEEEEEEEEEEEEEEEEEEEEAA 773
>gi|4505999 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 57.4 bits (137), Expect = 2e-08
Identities = 33/71 (46%), Positives = 46/71 (64%), Gaps = 6/71 (8%)
Query: 352 AAEKQMKDKQDEEQRLKEEEEDKKRKEEEE----AEDKEDDEDKDEDEEDEEDKEEDEEE 407
A K +D +DE +EEEED + EEE +E+ E++ED+D+ EE EED EE+EEE
Sbjct: 252 AKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEEEE 311
Query: 408 -DVPG-QAKDE 416
VPG + K+E
Sbjct: 312 MMVPGMEGKEE 322
Score = 28.9 bits (63), Expect = 9.0
Identities = 18/77 (23%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 320 QVKSGTIFDNFLITNDEAYAEEFGNETWGVTKA--AEKQMKDKQDEEQRLKEEEEDKKRK 377
+V F++ +DEA EE +E + + ++ ++++DE+ + EE+D++ +
Sbjct: 250 RVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEE 309
Query: 378 EEEEAEDKEDDEDKDED 394
EE E E+ D
Sbjct: 310 EEMMVPGMEGKEEPGSD 326
>gi|29826282 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 57.4 bits (137), Expect = 2e-08
Identities = 33/71 (46%), Positives = 46/71 (64%), Gaps = 6/71 (8%)
Query: 352 AAEKQMKDKQDEEQRLKEEEEDKKRKEEEE----AEDKEDDEDKDEDEEDEEDKEEDEEE 407
A K +D +DE +EEEED + EEE +E+ E++ED+D+ EE EED EE+EEE
Sbjct: 252 AKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEEEE 311
Query: 408 -DVPG-QAKDE 416
VPG + K+E
Sbjct: 312 MMVPGMEGKEE 322
Score = 28.9 bits (63), Expect = 9.0
Identities = 18/77 (23%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 320 QVKSGTIFDNFLITNDEAYAEEFGNETWGVTKA--AEKQMKDKQDEEQRLKEEEEDKKRK 377
+V F++ +DEA EE +E + + ++ ++++DE+ + EE+D++ +
Sbjct: 250 RVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEE 309
Query: 378 EEEEAEDKEDDEDKDED 394
EE E E+ D
Sbjct: 310 EEMMVPGMEGKEEPGSD 326
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 57.0 bits (136), Expect = 3e-08
Identities = 26/56 (46%), Positives = 40/56 (71%)
Query: 361 QDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDE 416
+D ++ E+EED++ EEE E +E+DED DED ED ED+EE+EEE+ + ++E
Sbjct: 112 EDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEE 167
Score = 54.3 bits (129), Expect = 2e-07
Identities = 25/55 (45%), Positives = 41/55 (74%), Gaps = 1/55 (1%)
Query: 355 KQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKD-EDEEDEEDKEEDEEED 408
++ + DE EE+E+ R+EEEE E++++D+D+D ED EDEE++EE+EEE+
Sbjct: 108 EEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEE 162
Score = 54.3 bits (129), Expect = 2e-07
Identities = 24/51 (47%), Positives = 42/51 (82%), Gaps = 1/51 (1%)
Query: 358 KDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEED 408
+D++DEE +EEEE+ + ++E++ ED ED ED++E+EE+EE++EE+EE +
Sbjct: 120 EDEEDEEGD-REEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENE 169
Score = 53.5 bits (127), Expect = 3e-07
Identities = 24/75 (32%), Positives = 49/75 (65%), Gaps = 4/75 (5%)
Query: 335 DEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDED 394
+E EE+ + E+ + ++EE+ ++EE+ED ++E+ ED ED+E+++E+
Sbjct: 103 EEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDED----DDEDGEDVEDEEEEEEE 158
Query: 395 EEDEEDKEEDEEEDV 409
EE+EE++EE+E+ +
Sbjct: 159 EEEEEEEEENEDHQM 173
Score = 52.0 bits (123), Expect = 1e-06
Identities = 23/54 (42%), Positives = 42/54 (77%), Gaps = 2/54 (3%)
Query: 362 DEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKD 415
DE++ ++EE D++ +EE E ED++DDED ++ E++EE++EE+EEE+ + +D
Sbjct: 119 DEDE--EDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENED 170
Score = 45.4 bits (106), Expect = 9e-05
Identities = 22/67 (32%), Positives = 42/67 (62%), Gaps = 5/67 (7%)
Query: 355 KQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKE-----EDEEEDV 409
+ M +K+++E E+ D+ E+EE E+ + +E+++ +EEDE+D E EDEEE+
Sbjct: 97 EDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEE 156
Query: 410 PGQAKDE 416
+ ++E
Sbjct: 157 EEEEEEE 163
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 27/96 (28%)
Query: 347 WGVTKAAEKQMKDKQDEEQRLKEEE-------------------EDKKRKEEEEAEDKED 387
+G A +++ +DKQ +E K + ED KEE+E E+ +
Sbjct: 53 YGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSE 112
Query: 388 DEDK--DEDEEDEE-DKEE-----DEEEDVPGQAKD 415
D D+ DEDEEDEE D+EE +E+ED +D
Sbjct: 113 DNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGED 148
Score = 41.2 bits (95), Expect = 0.002
Identities = 21/75 (28%), Positives = 43/75 (57%)
Query: 334 NDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDE 393
NDE E+ +E + E + +D+ D+E E+E+++ +EEEE E++E++ED
Sbjct: 114 NDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQM 173
Query: 394 DEEDEEDKEEDEEED 408
+ + ++ E++D
Sbjct: 174 NCHNTRIMQDTEKDD 188
Score = 35.0 bits (79), Expect = 0.13
Identities = 53/236 (22%), Positives = 87/236 (36%), Gaps = 48/236 (20%)
Query: 182 YEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPEH 241
+ VK D+S V+ D + + K+ +D ED DE D+ + + D ++ E
Sbjct: 78 FAVKADSSSVDECDDSDGTEDMDEKE-EDEGEEYSEDNDEPG--DEDEEDEEGDREEEEE 134
Query: 242 IPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSP 301
I + D ED ++ D E E E + E + + +N D++ + I
Sbjct: 135 IEEEDEDDDEDGEDVEDEEEE-------EEEEEEEEEEEENEDHQMNCHNTRIMQDTEKD 187
Query: 302 DPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQ 361
D + YDN+ DE A+ N + K AE
Sbjct: 188 DNNNDEYDNY-----------------------DELVAKSLLN----LGKIAE------- 213
Query: 362 DEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL 417
D R + E E + EDD DK+E+ + + D + DV + D L
Sbjct: 214 DAAYRARTESE----MNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSL 265
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 56.2 bits (134), Expect = 5e-08
Identities = 33/87 (37%), Positives = 55/87 (63%), Gaps = 6/87 (6%)
Query: 334 NDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDE 393
++E +EE ET +K K + + + E+E++++ E+E+ +D EDDED D+
Sbjct: 201 DEEDDSEEEAMET--TPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDED-DD 257
Query: 394 DEEDEEDKEEDEEEDV---PGQAKDEL 417
DE+DEE++EE+EEE V PG+ K E+
Sbjct: 258 DEDDEEEEEEEEEEPVKEAPGKRKKEM 284
Score = 52.0 bits (123), Expect = 1e-06
Identities = 23/72 (31%), Positives = 45/72 (62%), Gaps = 14/72 (19%)
Query: 351 KAAEKQMKDKQDEEQRLKEEEEDKKRKEEEE--------------AEDKEDDEDKDEDEE 396
K A+K+ D+++++ ++EE+D+ E+E+ A + EDDED ++DE+
Sbjct: 138 KNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDED 197
Query: 397 DEEDKEEDEEED 408
D++D+E+D EE+
Sbjct: 198 DDDDEEDDSEEE 209
Score = 48.9 bits (115), Expect = 8e-06
Identities = 26/87 (29%), Positives = 45/87 (51%), Gaps = 19/87 (21%)
Query: 348 GVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDK---------------- 391
G A+ K +++ EEE+D ++EE+ ED+++DED+
Sbjct: 126 GAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASE 185
Query: 392 ---DEDEEDEEDKEEDEEEDVPGQAKD 415
DED+ED+ED ++DEE+D +A +
Sbjct: 186 DEDDEDDEDDEDDDDDEEDDSEEEAME 212
Score = 47.4 bits (111), Expect = 2e-05
Identities = 26/75 (34%), Positives = 41/75 (54%), Gaps = 16/75 (21%)
Query: 354 EKQMKDKQDEEQRLKEEEEDKKR--------------KEEEEAEDKEDDEDKDEDEEDEE 399
E++ D +++E+ ++E+ED+ E+E+ ED EDDED D+DEED
Sbjct: 147 EEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEED-- 204
Query: 400 DKEEDEEEDVPGQAK 414
D EE+ E P + K
Sbjct: 205 DSEEEAMETTPAKGK 219
Score = 43.9 bits (102), Expect = 3e-04
Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 17/75 (22%)
Query: 351 KAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDE--------------- 395
K A K ++ + KE+ ++++ + EE E+ ++DED+DEDE
Sbjct: 125 KGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPAS 184
Query: 396 --EDEEDKEEDEEED 408
ED+ED E+DE++D
Sbjct: 185 EDEDDEDDEDDEDDD 199
Score = 38.9 bits (89), Expect = 0.009
Identities = 24/106 (22%), Positives = 47/106 (44%), Gaps = 24/106 (22%)
Query: 335 DEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDD------ 388
DE E+ + + AA K E E++ED + +++E +D E++
Sbjct: 156 DEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTP 215
Query: 389 ------------------EDKDEDEEDEEDKEEDEEEDVPGQAKDE 416
ED+DE+E+DE++ ++D+E+D +D+
Sbjct: 216 AKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDD 261
Score = 36.2 bits (82), Expect = 0.057
Identities = 15/64 (23%), Positives = 40/64 (62%)
Query: 353 AEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQ 412
AE + +++ DE++ ++E+D+ +E++ E++E++E++ E + K+E ++ +
Sbjct: 233 AEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPE 292
Query: 413 AKDE 416
AK +
Sbjct: 293 AKKQ 296
Score = 29.6 bits (65), Expect = 5.3
Identities = 27/100 (27%), Positives = 41/100 (41%), Gaps = 3/100 (3%)
Query: 187 DNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPD 246
D+ E S E+ + P K K + + D+ D + ED D E D D
Sbjct: 198 DDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDD 257
Query: 247 AKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYK 286
ED +EE + E E PV + P + + +Q P+ K
Sbjct: 258 ---DEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAK 294
Score = 28.9 bits (63), Expect = 9.0
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 369 EEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVP 410
+ + D K+ E +ED ED+ E EDEED EE +P
Sbjct: 9 KNQGDPKKMAPPPKEVEEDSEDE-EMSEDEEDDSSGEEVVIP 49
>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
Length = 569
Score = 56.2 bits (134), Expect = 5e-08
Identities = 25/66 (37%), Positives = 50/66 (75%), Gaps = 4/66 (6%)
Query: 351 KAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAED----KEDDEDKDEDEEDEEDKEEDEE 406
+A +++MK+K++EE + +EE + K+ KEEEE E+ +E++E ++++EE+ E K+E++E
Sbjct: 367 RAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDE 426
Query: 407 EDVPGQ 412
++ GQ
Sbjct: 427 DEDGGQ 432
Score = 52.0 bits (123), Expect = 1e-06
Identities = 26/62 (41%), Positives = 44/62 (70%), Gaps = 6/62 (9%)
Query: 354 EKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEED----KEEDEEEDV 409
E++MK K+++E+ +EEEE K+++EEEE +K ++E + +DEEDE++ K E E +
Sbjct: 384 EEEMKKKEEKEE--EEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQD 441
Query: 410 PG 411
PG
Sbjct: 442 PG 443
Score = 50.4 bits (119), Expect = 3e-06
Identities = 28/91 (30%), Positives = 55/91 (60%), Gaps = 15/91 (16%)
Query: 334 NDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDE 393
++E Y+E+ E A + +D+ +R++ +++ K KEEEE + +E+ + K+E
Sbjct: 340 DEEYYSEDEDQE-------ARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEE 392
Query: 394 DEEDEED--KEEDEEEDV------PGQAKDE 416
EE+EE+ K+++EEE++ G++KDE
Sbjct: 393 KEEEEEEEMKQKEEEEEIRNKNEEEGESKDE 423
Score = 44.7 bits (104), Expect = 2e-04
Identities = 19/65 (29%), Positives = 43/65 (66%), Gaps = 2/65 (3%)
Query: 354 EKQMKDKQDEEQRLKEEEEDKKRKEEEEAE--DKEDDEDKDEDEEDEEDKEEDEEEDVPG 411
+++ +++++EE + KEEEE+ + K EEE E D+ED+++ + + E +++ E+ G
Sbjct: 390 KEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYG 449
Query: 412 QAKDE 416
+ ++E
Sbjct: 450 EVEEE 454
Score = 37.7 bits (86), Expect = 0.019
Identities = 21/67 (31%), Positives = 38/67 (56%), Gaps = 3/67 (4%)
Query: 354 EKQMKDKQDEEQ---RLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVP 410
E++MK K++EE+ + +EE E K ++E+E ++ + + +D EE E EEE +
Sbjct: 398 EEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLD 457
Query: 411 GQAKDEL 417
D+L
Sbjct: 458 EAQDDDL 464
Score = 35.4 bits (80), Expect = 0.097
Identities = 20/62 (32%), Positives = 38/62 (61%), Gaps = 4/62 (6%)
Query: 351 KAAEKQMKDKQDEEQRLK-EEEEDKKRKEEEEAEDKED---DEDKDEDEEDEEDKEEDEE 406
K E+++++K +EE K EE+ED+ ++ E E ++D +E E EE+ D+ +D++
Sbjct: 404 KEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLDEAQDDD 463
Query: 407 ED 408
D
Sbjct: 464 LD 465
Score = 33.1 bits (74), Expect = 0.48
Identities = 17/74 (22%), Positives = 42/74 (56%), Gaps = 15/74 (20%)
Query: 358 KDKQDEEQRLKEEEEDKKRKEEEEAEDKE------DDEDKDEDEED---------EEDKE 402
+++ ++E+ E+E+ + R+ ++D+ E K+++EE+ +E+KE
Sbjct: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
Query: 403 EDEEEDVPGQAKDE 416
E+EEE++ + ++E
Sbjct: 395 EEEEEEMKQKEEEE 408
>gi|4504425 high-mobility group box 1 [Homo sapiens]
Length = 215
Score = 55.8 bits (133), Expect = 7e-08
Identities = 30/85 (35%), Positives = 48/85 (56%), Gaps = 22/85 (25%)
Query: 345 ETWGVTKAAEKQMKDKQDEEQRLKEE----------------------EEDKKRKEEEEA 382
E W T A +KQ +K+ + + K E E+ KK+KEEEE
Sbjct: 131 EMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEED 190
Query: 383 EDKEDDEDKDEDEEDEEDKEEDEEE 407
E+ E+DE+++EDEEDE+++E+D++E
Sbjct: 191 EEDEEDEEEEEDEEDEDEEEDDDDE 215
>gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo
sapiens]
Length = 142
Score = 55.8 bits (133), Expect = 7e-08
Identities = 22/61 (36%), Positives = 46/61 (75%)
Query: 348 GVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEE 407
G + ++ ++K+ EE+R +E+ ++KR+E + E +E+ E+++E+EE+EE++EE+EEE
Sbjct: 59 GTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEE 118
Query: 408 D 408
+
Sbjct: 119 E 119
Score = 55.8 bits (133), Expect = 7e-08
Identities = 24/53 (45%), Positives = 45/53 (84%), Gaps = 2/53 (3%)
Query: 354 EKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEE 406
EK+ ++K+ EE+R +E+ + KR+E+EE +KE++E+++E+EE+EE++EE+EE
Sbjct: 70 EKRREEKRREEKRREEKRREGKRREKEE--EKEEEEEEEEEEEEEEEEEEEEE 120
Score = 52.4 bits (124), Expect = 8e-07
Identities = 21/57 (36%), Positives = 42/57 (73%)
Query: 352 AAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEED 408
A K ++ EE+R +E+ ++KR+EE+ E K +++++++EE+EE++EE+EEE+
Sbjct: 58 AGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEE 114
Score = 46.2 bits (108), Expect = 5e-05
Identities = 19/54 (35%), Positives = 38/54 (70%)
Query: 363 EEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDE 416
+ QR +E+ ++KR+EE+ E+K + + E EE++E++EE+EEE+ + ++E
Sbjct: 64 KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEE 117
Score = 43.9 bits (102), Expect = 3e-04
Identities = 22/62 (35%), Positives = 43/62 (69%), Gaps = 8/62 (12%)
Query: 354 EKQMKDKQDEEQRL----KEEEEDKKRKEEEEAEDKEDDEDKDEDEED----EEDKEEDE 405
EK+ ++K+ EE+R +E+EE+K+ +EEEE E++E++E+++E+E ++E +
Sbjct: 75 EKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETET 134
Query: 406 EE 407
EE
Sbjct: 135 EE 136
Score = 40.8 bits (94), Expect = 0.002
Identities = 19/56 (33%), Positives = 40/56 (71%), Gaps = 1/56 (1%)
Query: 354 EKQMKDKQDE-EQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEED 408
EK+ ++K+ E ++R KEEE++++ +EEEE E++E++E+++E +E + E +
Sbjct: 80 EKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETE 135
Score = 40.8 bits (94), Expect = 0.002
Identities = 19/53 (35%), Positives = 35/53 (66%)
Query: 354 EKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEE 406
EK+ + K+ E++ KEEEE+++ +EEEE E++E++E E + E +E+
Sbjct: 85 EKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEK 137
Score = 35.4 bits (80), Expect = 0.097
Identities = 15/52 (28%), Positives = 33/52 (63%)
Query: 351 KAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKE 402
K E + ++K++E++ +EEEE+++ +EEEE E++ + E E +++
Sbjct: 86 KRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEK 137
Score = 35.0 bits (79), Expect = 0.13
Identities = 15/51 (29%), Positives = 32/51 (62%)
Query: 351 KAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDK 401
+ +++ K+++ EE+ +EEEE+++ +EEEE E ++ + E EE +
Sbjct: 88 REGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
Score = 29.6 bits (65), Expect = 5.3
Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 8/59 (13%)
Query: 335 DEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKK--------RKEEEEAEDK 385
+E EE E K EK+ +++++EE+ +EEEE+++ R+ E E E+K
Sbjct: 79 EEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEK 137
Score = 28.9 bits (63), Expect = 9.0
Identities = 13/69 (18%), Positives = 33/69 (47%)
Query: 348 GVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEE 407
G+T + ++ + K ++ EE+ +++ E+K +E+ E K ++EE
Sbjct: 38 GLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEE 97
Query: 408 DVPGQAKDE 416
+ + ++E
Sbjct: 98 EKEEEEEEE 106
>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
Length = 1390
Score = 54.7 bits (130), Expect = 2e-07
Identities = 20/55 (36%), Positives = 40/55 (72%)
Query: 354 EKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEED 408
+++ D Q+ EE ED++ +++ E ED EDD+D D+D++D++D+++++EED
Sbjct: 231 DEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEED 285
Score = 51.6 bits (122), Expect = 1e-06
Identities = 20/72 (27%), Positives = 49/72 (68%), Gaps = 1/72 (1%)
Query: 346 TWGVTKAAEKQMKDKQD-EEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEED 404
T G K ++ ++ D +E ++ EE + ++ E++ ED++D++D D+D++D++D +ED
Sbjct: 220 TRGKQKDIQRTDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDED 279
Query: 405 EEEDVPGQAKDE 416
+E++ G+ +++
Sbjct: 280 DEDEEDGEEENQ 291
Score = 47.8 bits (112), Expect = 2e-05
Identities = 19/58 (32%), Positives = 38/58 (65%)
Query: 350 TKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEE 407
T E ++ ++ E + E++ + + E+++ +D +DD+D DED+EDEED EE+ ++
Sbjct: 235 TDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEENQK 292
Score = 42.4 bits (98), Expect = 8e-04
Identities = 17/59 (28%), Positives = 37/59 (62%)
Query: 345 ETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEE 403
ET + + + ++ +D+E E+ED + ++++ +D +DD++ DEDEED E++ +
Sbjct: 233 ETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEENQ 291
Score = 40.0 bits (92), Expect = 0.004
Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 19/105 (18%)
Query: 321 VKSGTIFDNFLITNDEAYAEEFGN------------ETWGVTKAAEKQ-----MKDKQDE 363
V +FD + EA ++ + E GV E+ + KQ +
Sbjct: 167 VNQSMLFDKLITNTAEAVLQKMDDMKKMRRQRMRELEDLGVFNETEESNLNMYTRGKQKD 226
Query: 364 EQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEED 408
QR EE D + E +E+ ED E +D+ E+ ED E+D+++D
Sbjct: 227 IQRTDEETTDNQEGSVESSEEGEDQEHEDDGED--EDDEDDDDDD 269
Score = 37.4 bits (85), Expect = 0.025
Identities = 14/62 (22%), Positives = 38/62 (61%)
Query: 340 EEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEE 399
EE + G +++E+ + +++ +++E+D ++++ +D EDDED+++ EE+ +
Sbjct: 232 EETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEENQ 291
Query: 400 DK 401
+
Sbjct: 292 KR 293
>gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens]
Length = 488
Score = 54.7 bits (130), Expect = 2e-07
Identities = 24/52 (46%), Positives = 41/52 (78%), Gaps = 3/52 (5%)
Query: 348 GVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEE 399
GV KAA+ + K +++E + E+EED++ +++EE ED+EDDED++ED +DE+
Sbjct: 310 GVVKAAKSKKKKEEEENE---EDEEDEEEEKDEEDEDEEDDEDEEEDGDDEQ 358
Score = 54.3 bits (129), Expect = 2e-07
Identities = 32/87 (36%), Positives = 48/87 (55%), Gaps = 23/87 (26%)
Query: 345 ETWGVTKAAEKQMKDKQDEEQRLKEEEE----------------------DKKRKEEEEA 382
E W T A +KQ +K+ + + K E++ KK+KEEEE
Sbjct: 267 EMWNNTAADDKQPYEKRSAKLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEEN 326
Query: 383 EDKEDDEDKDEDEEDE-EDKEEDEEED 408
E+ E+DE++++DEEDE E+ +EDEEED
Sbjct: 327 EEDEEDEEEEKDEEDEDEEDDEDEEED 353
>gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens]
Length = 487
Score = 54.7 bits (130), Expect = 2e-07
Identities = 28/86 (32%), Positives = 49/86 (56%), Gaps = 22/86 (25%)
Query: 345 ETWGVTKAAEKQMKDKQDEEQRLKEEEE----------------------DKKRKEEEEA 382
E W T A +KQ +K+ + + K E++ KK+KEEEE
Sbjct: 267 EMWNNTAADDKQPYEKRSAKLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEEN 326
Query: 383 EDKEDDEDKDEDEEDEEDKEEDEEED 408
E+ E+DE++++DEEDE+++++++EED
Sbjct: 327 EEDEEDEEEEKDEEDEDEEDDEDEED 352
Score = 50.1 bits (118), Expect = 4e-06
Identities = 20/48 (41%), Positives = 37/48 (77%)
Query: 348 GVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDE 395
GV KAA+ + K +++E + +E+EE++K +E+E+ ED ED+ED D+++
Sbjct: 310 GVVKAAKSKKKKEEEENEEDEEDEEEEKDEEDEDEEDDEDEEDGDDEQ 357
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 54.7 bits (130), Expect = 2e-07
Identities = 19/50 (38%), Positives = 45/50 (90%)
Query: 358 KDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEE 407
++ ++EE+ ++EEE++++++E+EE E+KE+++++DE+EE++E K+ +EE+
Sbjct: 121 EEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEK 170
Score = 51.6 bits (122), Expect = 1e-06
Identities = 25/61 (40%), Positives = 43/61 (70%), Gaps = 4/61 (6%)
Query: 361 QDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEED----EEEDVPGQAKDE 416
++EE +EEE +++ KEEE+ ED+E++E ++E EEDEE++E++ EEE V + E
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
Query: 417 L 417
+
Sbjct: 179 I 179
Score = 50.1 bits (118), Expect = 4e-06
Identities = 26/96 (27%), Positives = 53/96 (55%)
Query: 312 GVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEE 371
GV +W + + + A E + G+ E+ +++++ E+ KEEE
Sbjct: 79 GVSQAKIWGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEE 138
Query: 372 EDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEE 407
+++ +EEE+ E+KE+DE+++E E + ++E+ EEE
Sbjct: 139 KEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEE 174
Score = 46.6 bits (109), Expect = 4e-05
Identities = 16/56 (28%), Positives = 46/56 (82%)
Query: 354 EKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDV 409
E++++++++E + ++EEE ++ +EEEE E+++++++++E++E ++ +EE EE++
Sbjct: 120 EEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEI 175
Score = 45.8 bits (107), Expect = 7e-05
Identities = 19/54 (35%), Positives = 41/54 (75%)
Query: 354 EKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEE 407
E++ + +++E++ KEE+E+++ KEEE+ ED+E++E + + E+E+ +EE + E
Sbjct: 125 EEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
Score = 43.9 bits (102), Expect = 3e-04
Identities = 20/70 (28%), Positives = 46/70 (65%)
Query: 339 AEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDE 398
AEE + + E + ++++ EE+ +EE+E+ + +EE+E E +ED+E+++++ +
Sbjct: 107 AEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKM 166
Query: 399 EDKEEDEEED 408
E+++ +EE D
Sbjct: 167 EEEKVEEEID 176
Score = 43.9 bits (102), Expect = 3e-04
Identities = 16/56 (28%), Positives = 42/56 (75%)
Query: 354 EKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDV 409
E++ ++ ++EE+ ++EE++++ ++EEE E+ E++E+K+ + +EE EE+ + ++
Sbjct: 124 EEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEI 179
Score = 38.9 bits (89), Expect = 0.009
Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 5/65 (7%)
Query: 335 DEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDED 394
+E EE E K EK+ ++++E++ KEE+E+ EEE E K+ +E+K E+
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEE-----EEEKEGKKMEEEKVEE 173
Query: 395 EEDEE 399
E D E
Sbjct: 174 EIDTE 178
Score = 29.3 bits (64), Expect = 6.9
Identities = 16/43 (37%), Positives = 27/43 (62%), Gaps = 4/43 (9%)
Query: 378 EEEEAEDKEDDEDKDEDEEDEE----DKEEDEEEDVPGQAKDE 416
EE A+ E+++ +EE+EE +KEE++EED + K+E
Sbjct: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEE 150
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 54.7 bits (130), Expect = 2e-07
Identities = 26/62 (41%), Positives = 45/62 (72%), Gaps = 4/62 (6%)
Query: 359 DKQDEEQRLKEEEEDKKRKEEEEAED----KEDDEDKDEDEEDEEDKEEDEEEDVPGQAK 414
+ DEE+ +EEEE+++ +EEEE ED +ED+E+ E+EE+EE++ E+E E+ G+ +
Sbjct: 884 NSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELE 943
Query: 415 DE 416
+E
Sbjct: 944 EE 945
Score = 54.7 bits (130), Expect = 2e-07
Identities = 25/58 (43%), Positives = 46/58 (79%), Gaps = 3/58 (5%)
Query: 354 EKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEE---DEEDKEEDEEED 408
E++ +++++EE+ +EEEED++ EEE E++E+ E++ E+EE +EE++EEDEEE+
Sbjct: 897 EEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEE 954
Score = 53.9 bits (128), Expect = 3e-07
Identities = 26/78 (33%), Positives = 51/78 (65%)
Query: 329 NFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDD 388
N +++E EE E + E+ ++++++E+ EEEE+++ + EEE E++E +
Sbjct: 882 NINSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGE 941
Query: 389 EDKDEDEEDEEDKEEDEE 406
+++E+EEDEE++EE EE
Sbjct: 942 LEEEEEEEDEEEEEELEE 959
Score = 52.0 bits (123), Expect = 1e-06
Identities = 24/68 (35%), Positives = 50/68 (73%), Gaps = 4/68 (5%)
Query: 354 EKQMKDKQDEEQRLKEEEEDKKRKEEEE----AEDKEDDEDKDEDEEDEEDKEEDEEEDV 409
E++ +++++EE+ +EEEED + +EE+E E++E++E+ +E+ E+EE + E+EEE+
Sbjct: 890 EEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEE 949
Query: 410 PGQAKDEL 417
+ ++EL
Sbjct: 950 DEEEEEEL 957
Score = 51.6 bits (122), Expect = 1e-06
Identities = 22/59 (37%), Positives = 45/59 (76%)
Query: 349 VTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEE 407
+ + E++ +++++EE+ +EEEE++ +EEEE E++ +E+++E+EE EE+ EE+E E
Sbjct: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGE 941
Score = 50.8 bits (120), Expect = 2e-06
Identities = 20/65 (30%), Positives = 51/65 (78%)
Query: 352 AAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPG 411
+++++ +++++EE+ +EEEE+++ EEEE +++E E+++E+EE+ E++ E+EE ++
Sbjct: 885 SSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEE 944
Query: 412 QAKDE 416
+ ++E
Sbjct: 945 EEEEE 949
Score = 50.4 bits (119), Expect = 3e-06
Identities = 25/75 (33%), Positives = 49/75 (65%)
Query: 335 DEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDED 394
+E EE E + E ++++DEE+ +EEEE+++ EEE E++ + E+++E+
Sbjct: 889 EEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEE 948
Query: 395 EEDEEDKEEDEEEDV 409
E++EE++E +E ED+
Sbjct: 949 EDEEEEEELEEVEDL 963
Score = 38.5 bits (88), Expect = 0.011
Identities = 22/76 (28%), Positives = 43/76 (56%)
Query: 335 DEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDED 394
+E E+F E + E++ +++++ E+ +EEE + + +EEEE E++E++ ++ ED
Sbjct: 903 EEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVED 962
Query: 395 EEDEEDKEEDEEEDVP 410
E E EE P
Sbjct: 963 LEFGTAGGEVEEGAPP 978
Score = 35.8 bits (81), Expect = 0.074
Identities = 17/46 (36%), Positives = 31/46 (67%), Gaps = 3/46 (6%)
Query: 371 EEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDE 416
EED ++++E++E+++E+EE+E EE+EEED + +DE
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEE---EEEEEEDFEEEEEDE 917
>gi|224586804 DNA-directed DNA polymerase epsilon 3 [Homo sapiens]
Length = 147
Score = 54.3 bits (129), Expect = 2e-07
Identities = 24/69 (34%), Positives = 46/69 (66%)
Query: 341 EFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEED 400
EF + +A E ++++ +++ +++++DK +K + E +DK DED DEDEE E+
Sbjct: 77 EFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEE 136
Query: 401 KEEDEEEDV 409
+E++EEE+V
Sbjct: 137 EEQNEEEEV 145
Score = 35.0 bits (79), Expect = 0.13
Identities = 18/61 (29%), Positives = 37/61 (60%), Gaps = 2/61 (3%)
Query: 355 KQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAK 414
K+ + EQ+ K+E ++K+K++++ D E+ +DK DE D ++ EE EE+ + +
Sbjct: 86 KEALEAYRREQKGKKEASEQKKKDKDKKTDSEE-QDKSRDE-DNDEDEERLEEEEQNEEE 143
Query: 415 D 415
+
Sbjct: 144 E 144
Score = 28.9 bits (63), Expect = 9.0
Identities = 13/51 (25%), Positives = 30/51 (58%), Gaps = 3/51 (5%)
Query: 369 EEEEDKKRKEEEEAEDKEDDEDKDEDEE---DEEDKEEDEEEDVPGQAKDE 416
+E + R+E++ ++ + + KD+D++ +E+DK DE+ D + +E
Sbjct: 86 KEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEE 136
>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
Length = 4374
Score = 53.9 bits (128), Expect = 3e-07
Identities = 25/82 (30%), Positives = 46/82 (56%)
Query: 335 DEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDED 394
DE+ + +E A +++D L E+E++ +EE+ + ED++D ++
Sbjct: 2375 DESQEDVLMDEAPSNLSQASTLQANREDSMNILDPEDEEEHTQEEDSSGSNEDEDDSQDE 2434
Query: 395 EEDEEDKEEDEEEDVPGQAKDE 416
EE+EE+ EED++ED G+ DE
Sbjct: 2435 EEEEEEDEEDDQEDDEGEEGDE 2456
Score = 53.1 bits (126), Expect = 4e-07
Identities = 29/81 (35%), Positives = 44/81 (54%), Gaps = 8/81 (9%)
Query: 335 DEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEE--------EEDKKRKEEEEAEDKE 386
DEA + T + + D +DEE+ +EE E+D + +EEEE ED+E
Sbjct: 2384 DEAPSNLSQASTLQANREDSMNILDPEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEEDEE 2443
Query: 387 DDEDKDEDEEDEEDKEEDEEE 407
DD++ DE EE +ED ++D E
Sbjct: 2444 DDQEDDEGEEGDEDDDDDGSE 2464
Score = 44.3 bits (103), Expect = 2e-04
Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 5/58 (8%)
Query: 354 EKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDE-EEDVP 410
E +DE+ EEEE++ E+E +D+EDDE ++ DE+D++D E E +ED P
Sbjct: 2419 EDSSGSNEDEDDSQDEEEEEE----EDEEDDQEDDEGEEGDEDDDDDGSEMELDEDYP 2472
Score = 31.6 bits (70), Expect = 1.4
Identities = 20/45 (44%), Positives = 26/45 (57%), Gaps = 2/45 (4%)
Query: 356 QMKDKQDEEQRLKEEEEDKKR--KEEEEAEDKEDDEDKDEDEEDE 398
Q + +E KEEEE K R +EEEEA+ E +D D E+DE
Sbjct: 1391 QRAESPEEVACRKEEEERKAREKQEEEEAKCLEKFQDADPLEQDE 1435
Score = 30.8 bits (68), Expect = 2.4
Identities = 17/46 (36%), Positives = 27/46 (58%), Gaps = 4/46 (8%)
Query: 364 EQRLKEEEEDKKRKEEEEAEDKEDDEDKD----EDEEDEEDKEEDE 405
+QR + EE RKEEEE + +E E+++ E +D + E+DE
Sbjct: 1390 DQRAESPEEVACRKEEEERKAREKQEEEEAKCLEKFQDADPLEQDE 1435
Score = 28.9 bits (63), Expect = 9.0
Identities = 13/51 (25%), Positives = 28/51 (54%)
Query: 357 MKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEE 407
++D++ EE+R K ++ + + + + KED E++D+ + K D E
Sbjct: 2681 LRDEELEERREKRRKQLAEEETKITDKGKEDKENRDQSAQCTASKSNDSTE 2731
>gi|13654270 LAS1-like [Homo sapiens]
Length = 734
Score = 53.5 bits (127), Expect = 3e-07
Identities = 26/70 (37%), Positives = 48/70 (68%), Gaps = 8/70 (11%)
Query: 339 AEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDE 398
+ FG+E A+ Q +++Q +KEEE+++K ++ E++E+++D++E+EEDE
Sbjct: 543 SSSFGSE-------AKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDE 595
Query: 399 EDKEEDEEED 408
+D E+DEEED
Sbjct: 596 DD-EDDEEED 604
Score = 43.1 bits (100), Expect = 5e-04
Identities = 18/62 (29%), Positives = 37/62 (59%)
Query: 347 WGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEE 406
W V A+ + + ++Q + D K +E+EE E D +++E+ +D+E++EEDE+
Sbjct: 537 WSVKPASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDED 596
Query: 407 ED 408
++
Sbjct: 597 DE 598
Score = 28.9 bits (63), Expect = 9.0
Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 9/63 (14%)
Query: 364 EQRLKEEEEDKKRKEEEEAEDKEDD---------EDKDEDEEDEEDKEEDEEEDVPGQAK 414
E L+E E ++ +E E ED+E+D E K E ++D + E D + D +
Sbjct: 190 ENSLRETWELEEFREGIEEEDQEEDKNIVVDDITEQKPEPQDDGKSTESDVKADGDSKGS 249
Query: 415 DEL 417
+E+
Sbjct: 250 EEV 252
>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
Length = 1759
Score = 53.1 bits (126), Expect = 4e-07
Identities = 23/50 (46%), Positives = 39/50 (78%), Gaps = 1/50 (2%)
Query: 368 KEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL 417
+E+EE++ EEEAED ED++D DED++DE+D E+D++ED+ +++ L
Sbjct: 1675 QEDEEEELELPEEEAEDDEDEDD-DEDDDDEDDDEDDDDEDLRTDSEESL 1723
Score = 51.2 bits (121), Expect = 2e-06
Identities = 25/64 (39%), Positives = 40/64 (62%), Gaps = 1/64 (1%)
Query: 352 AAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPG 411
AA ++DEE+ L+ EE+ + E+E+ ++ +DDED DED +D+ED D EE +P
Sbjct: 1667 AAAAGESSQEDEEEELELPEEEAEDDEDEDDDEDDDDEDDDED-DDDEDLRTDSEESLPE 1725
Query: 412 QAKD 415
A +
Sbjct: 1726 AAAE 1729
Score = 33.1 bits (74), Expect = 0.48
Identities = 12/39 (30%), Positives = 27/39 (69%)
Query: 378 EEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDE 416
E + +++E+ E +E+ ED+ED+++DE++D +D+
Sbjct: 1672 ESSQEDEEEELELPEEEAEDDEDEDDDEDDDDEDDDEDD 1710
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.135 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,017,693
Number of Sequences: 37866
Number of extensions: 1169109
Number of successful extensions: 57362
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1257
Number of HSP's successfully gapped in prelim test: 294
Number of HSP's that attempted gapping in prelim test: 12797
Number of HSP's gapped (non-prelim): 20516
length of query: 417
length of database: 18,247,518
effective HSP length: 105
effective length of query: 312
effective length of database: 14,271,588
effective search space: 4452735456
effective search space used: 4452735456
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.