Search of human proteins with 4757748

Search of human proteins with 4757748

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]
         (454 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]             912   0.0  
gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]            891   0.0  
gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]            874   0.0  
gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]            856   0.0  
gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]            853   0.0  
gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]            840   0.0  
gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]           802   0.0  
gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]            796   0.0  
gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]            769   0.0  
gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]            585   e-167
gi|21536423 amphiphysin isoform 2 [Homo sapiens]                      357   9e-99
gi|4502081 amphiphysin isoform 1 [Homo sapiens]                       357   9e-99
gi|49472835 bridging integrator 2 [Homo sapiens]                      308   9e-84
gi|8923904 bridging integrator 3 [Homo sapiens]                        57   3e-08
gi|39930351 dynamin binding protein [Homo sapiens]                     49   7e-06
gi|49640014 ubiquitin associated and SH3 domain containing, A sh...    46   6e-05
gi|9507221 ubiquitin associated and SH3 domain containing, A lon...    46   6e-05
gi|4826964 UV excision repair protein RAD23 homolog A [Homo sapi...    45   1e-04
gi|115527120 nebulin [Homo sapiens]                                    44   2e-04
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    44   3e-04
gi|40807452 peroxisome proliferator-activated receptor gamma, co...    42   9e-04
gi|7662162 ALEX2 protein [Homo sapiens]                                42   9e-04
gi|29540562 ALEX2 protein [Homo sapiens]                               42   9e-04
gi|219842343 glutamate receptor, metabotropic 5 isoform a precur...    42   0.001
gi|4504143 glutamate receptor, metabotropic 5 isoform b precurso...    42   0.001
gi|241982780 programmed cell death 6 interacting protein isoform...    42   0.001
gi|22027538 programmed cell death 6 interacting protein isoform ...    42   0.001
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     42   0.001
gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo ...    41   0.003
gi|239749199 PREDICTED: hypothetical protein XP_002346952 [Homo ...    41   0.003

>gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]
          Length = 454

 Score =  912 bits (2357), Expect = 0.0
 Identities = 454/454 (100%), Positives = 454/454 (100%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
           KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300

Query: 301 EPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 360
           EPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP
Sbjct: 301 EPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 360

Query: 361 ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD 420
           ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD
Sbjct: 361 ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD 420

Query: 421 EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 454
           EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 421 EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 454


>gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]
          Length = 497

 Score =  891 bits (2303), Expect = 0.0
 Identities = 454/497 (91%), Positives = 454/497 (91%), Gaps = 43/497 (8%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
           KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300

Query: 301 EPAGGATPGATLPKS-------------------------------------------PS 317
           EPAGGATPGATLPKS                                           PS
Sbjct: 301 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 360

Query: 318 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 377
           QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD
Sbjct: 361 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 420

Query: 378 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 437
           LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE
Sbjct: 421 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 480

Query: 438 LEKCRGVFPENFTERVP 454
           LEKCRGVFPENFTERVP
Sbjct: 481 LEKCRGVFPENFTERVP 497


>gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]
          Length = 439

 Score =  874 bits (2258), Expect = 0.0
 Identities = 439/454 (96%), Positives = 439/454 (96%), Gaps = 15/454 (3%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
           KQHGSNTFTVKAQP               SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQP---------------SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 285

Query: 301 EPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 360
           EPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP
Sbjct: 286 EPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 345

Query: 361 ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD 420
           ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD
Sbjct: 346 ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD 405

Query: 421 EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 454
           EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 406 EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 439


>gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]
          Length = 475

 Score =  856 bits (2211), Expect = 0.0
 Identities = 439/490 (89%), Positives = 439/490 (89%), Gaps = 51/490 (10%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
           KQHGSNTFTVKAQP               SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQP---------------SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 285

Query: 301 EPAGGATPGATLPKSPS------------------------------------QPAEASE 324
           EPAGGATPGATLPKSPS                                    QPAEASE
Sbjct: 286 EPAGGATPGATLPKSPSQPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASE 345

Query: 325 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF 384
           VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF
Sbjct: 346 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF 405

Query: 385 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 444
           KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV
Sbjct: 406 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 465

Query: 445 FPENFTERVP 454
           FPENFTERVP
Sbjct: 466 FPENFTERVP 475


>gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]
          Length = 482

 Score =  853 bits (2204), Expect = 0.0
 Identities = 439/497 (88%), Positives = 439/497 (88%), Gaps = 58/497 (11%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
           KQHGSNTFTVKAQP               SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQP---------------SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 285

Query: 301 EPAGGATPGATLPKS-------------------------------------------PS 317
           EPAGGATPGATLPKS                                           PS
Sbjct: 286 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 345

Query: 318 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 377
           QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD
Sbjct: 346 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 405

Query: 378 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 437
           LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE
Sbjct: 406 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 465

Query: 438 LEKCRGVFPENFTERVP 454
           LEKCRGVFPENFTERVP
Sbjct: 466 LEKCRGVFPENFTERVP 482


>gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]
          Length = 506

 Score =  840 bits (2169), Expect = 0.0
 Identities = 439/521 (84%), Positives = 439/521 (84%), Gaps = 82/521 (15%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKN 269
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP               
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP--------------- 285

Query: 270 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPS------------ 317
           SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPS            
Sbjct: 286 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPS 345

Query: 318 ------------------------QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPA 353
                                   QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPA
Sbjct: 346 GEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPA 405

Query: 354 VVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPF 413
           VVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPF
Sbjct: 406 VVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPF 465

Query: 414 QNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 454
           QNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 466 QNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 506


>gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]
          Length = 409

 Score =  802 bits (2071), Expect = 0.0
 Identities = 409/454 (90%), Positives = 409/454 (90%), Gaps = 45/454 (9%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
           KQHGSNTFTVKAQP               SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQP---------------SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 285

Query: 301 EPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 360
           EPAGGATPGATLPKSPSQ                              SSLPAVVVETFP
Sbjct: 286 EPAGGATPGATLPKSPSQ------------------------------SSLPAVVVETFP 315

Query: 361 ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD 420
           ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD
Sbjct: 316 ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD 375

Query: 421 EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 454
           EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 376 EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 409


>gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]
          Length = 518

 Score =  796 bits (2056), Expect = 0.0
 Identities = 420/533 (78%), Positives = 427/533 (80%), Gaps = 94/533 (17%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
           KQHGSNTFTVKAQP               SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQP---------------SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 285

Query: 301 EPAGGATPGATLPKSPSQ----------------------------------------PA 320
           EPAGGATPGATLPKSPSQ                                        P+
Sbjct: 286 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 345

Query: 321 EASEVAGGTQPA---------------AGAQEPGETAASEA------------------- 346
           + +E   G+ P+               +   EPG    +EA                   
Sbjct: 346 QPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 405

Query: 347 -----ASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 401
                ASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ
Sbjct: 406 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 465

Query: 402 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 454
           LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 466 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 518


>gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]
          Length = 550

 Score =  769 bits (1986), Expect = 0.0
 Identities = 419/565 (74%), Positives = 423/565 (74%), Gaps = 126/565 (22%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKN 269
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP               
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP--------------- 285

Query: 270 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ---PAEASEVA 326
           SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ   P   SE A
Sbjct: 286 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQA 345

Query: 327 G--------------------------------GTQPAAGAQEPGETA------------ 342
                                             T+  AG+   GE +            
Sbjct: 346 SLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPS 405

Query: 343 ------------ASEAASSSLPA---------------------VVVETFPATVNGTVEG 369
                       ASE A  + PA                     VVVETFPATVNGTVEG
Sbjct: 406 QTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEG 465

Query: 370 GSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKE 429
           GSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKE
Sbjct: 466 GSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKE 525

Query: 430 SDWNQHKELEKCRGVFPENFTERVP 454
           SDWNQHKELEKCRGVFPENFTERVP
Sbjct: 526 SDWNQHKELEKCRGVFPENFTERVP 550


>gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]
          Length = 593

 Score =  585 bits (1507), Expect = e-167
 Identities = 310/397 (78%), Positives = 318/397 (80%), Gaps = 55/397 (13%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKN 269
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP               
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP--------------- 285

Query: 270 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAGGT 329
           SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ  +   V    
Sbjct: 286 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPV---- 341

Query: 330 QPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGT 366
                   P  T + E     + ++  +TF   ++ T
Sbjct: 342 -----PPPPKHTPSKEVKQEQILSLFEDTFVPEISVT 373



 Score =  288 bits (737), Expect = 7e-78
 Identities = 148/175 (84%), Positives = 152/175 (86%), Gaps = 7/175 (4%)

Query: 284 PDGSPAATPEIRVNHEPEPAGG----ATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPG 339
           P  SPA +     + EP  A G    + P  T    P+QPAEASEVAGGTQPAAGAQEPG
Sbjct: 422 PTESPAGSLP---SGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPG 478

Query: 340 ETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDE 399
           ETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDE
Sbjct: 479 ETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDE 538

Query: 400 LQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 454
           LQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 539 LQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 593


>gi|21536423 amphiphysin isoform 2 [Homo sapiens]
          Length = 653

 Score =  357 bits (917), Expect = 9e-99
 Identities = 184/318 (57%), Positives = 226/318 (71%), Gaps = 19/318 (5%)

Query: 9   VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
           +  G  A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q  EGTRLQ++LR Y
Sbjct: 4   IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63

Query: 69  LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
           LA++K M EAS KL E L EVYEPDW GR++   + E  D+LW D+HQKLVD +LLT+DT
Sbjct: 64  LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123

Query: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
           YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE  KAQKVFEE 
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183

Query: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
           NVDLQEELPSLW+ RVGFYVNTF++++ LE  FHKE++ L   L +V+  L  QH    F
Sbjct: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243

Query: 249 TVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGAT 307
           T++  P               SD+ P +  K+PSPP + SP  +P    NH   P   A+
Sbjct: 244 TIQGAP---------------SDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---AS 285

Query: 308 PGATLPKSPSQPAEASEV 325
           P    P+SPSQ  +   V
Sbjct: 286 PAPARPRSPSQTRKGPPV 303



 Score =  112 bits (279), Expect = 9e-25
 Identities = 64/181 (35%), Positives = 92/181 (50%), Gaps = 16/181 (8%)

Query: 285 DGSPAATPEIRVNHEPEPAGGATPGATL-PKSPSQPAEASEVAGGTQPAAGAQEPGETAA 343
           +G+ +A PE        P     P   + P S  +    +E+  G +P    +E  E AA
Sbjct: 476 EGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEP----KETTEDAA 531

Query: 344 SEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDY 392
               +S  P +  E  P             G  D           LPPGF++KV+  HD+
Sbjct: 532 PPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDF 591

Query: 393 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 452
            A ++DEL L+ GDVVLV+P  +  +QD GWL+GVKESDW Q+++L   +G+FPENFT R
Sbjct: 592 EAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRR 651

Query: 453 V 453
           +
Sbjct: 652 L 652


>gi|4502081 amphiphysin isoform 1 [Homo sapiens]
          Length = 695

 Score =  357 bits (917), Expect = 9e-99
 Identities = 184/318 (57%), Positives = 226/318 (71%), Gaps = 19/318 (5%)

Query: 9   VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
           +  G  A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q  EGTRLQ++LR Y
Sbjct: 4   IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63

Query: 69  LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
           LA++K M EAS KL E L EVYEPDW GR++   + E  D+LW D+HQKLVD +LLT+DT
Sbjct: 64  LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123

Query: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
           YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE  KAQKVFEE 
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183

Query: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
           NVDLQEELPSLW+ RVGFYVNTF++++ LE  FHKE++ L   L +V+  L  QH    F
Sbjct: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243

Query: 249 TVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGAT 307
           T++  P               SD+ P +  K+PSPP + SP  +P    NH   P   A+
Sbjct: 244 TIQGAP---------------SDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---AS 285

Query: 308 PGATLPKSPSQPAEASEV 325
           P    P+SPSQ  +   V
Sbjct: 286 PAPARPRSPSQTRKGPPV 303



 Score =  112 bits (279), Expect = 9e-25
 Identities = 64/181 (35%), Positives = 92/181 (50%), Gaps = 16/181 (8%)

Query: 285 DGSPAATPEIRVNHEPEPAGGATPGATL-PKSPSQPAEASEVAGGTQPAAGAQEPGETAA 343
           +G+ +A PE        P     P   + P S  +    +E+  G +P    +E  E AA
Sbjct: 518 EGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEP----KETTEDAA 573

Query: 344 SEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDY 392
               +S  P +  E  P             G  D           LPPGF++KV+  HD+
Sbjct: 574 PPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDF 633

Query: 393 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 452
            A ++DEL L+ GDVVLV+P  +  +QD GWL+GVKESDW Q+++L   +G+FPENFT R
Sbjct: 634 EAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRR 693

Query: 453 V 453
           +
Sbjct: 694 L 694


>gi|49472835 bridging integrator 2 [Homo sapiens]
          Length = 565

 Score =  308 bits (788), Expect = 9e-84
 Identities = 182/396 (45%), Positives = 235/396 (59%), Gaps = 35/396 (8%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAE G  G  AG  A  VQKK +RAQEKVLQKLGKA ETKDE+FEQ   NF +Q  EG +
Sbjct: 1   MAE-GKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHK 59

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           L KDL+ +L++VK MHE+SK+++E LQE+Y  +W G +E   I  NNDLLW DY +KL D
Sbjct: 60  LYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLAD 119

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QA+ TM+ Y+ QF +IK RIAKRGRKLVDYDSARHH E++Q AKKKDEAK AKAEEE  K
Sbjct: 120 QAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNK 179

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQ VFE++N +L EELP L+NSR+G YV  FQ+I+ L + F++EMSKLN NL +V+  LE
Sbjct: 180 AQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLE 239

Query: 241 KQHGSNTFTVK---------------------AQPRKKSKLFSRLRRKKNSDNAPAKGNK 279
           KQH +  F VK                     + P       S L  K  S++  A  + 
Sbjct: 240 KQHSNKVFVVKGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDL 299

Query: 280 SPSPPDGSPAA-----TPEIRVNHEPEPAGGATPGATLP----KSPSQPAEASEVAGGTQ 330
           +P    G   +       E  +  E   A  +     LP     + +QP+  +E A   +
Sbjct: 300 APDAAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQE 359

Query: 331 ---PAAGAQEP-GETAASEAASSSLPAVVVETFPAT 362
              P++    P G  + S   SSS   VV+ T  A+
Sbjct: 360 EVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTAS 395


>gi|8923904 bridging integrator 3 [Homo sapiens]
          Length = 253

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 55/195 (28%), Positives = 100/195 (51%), Gaps = 14/195 (7%)

Query: 53  KQLTEGTR-LQKDLRTYLASVKAMHEASKKLNECL--QEVYEPDWPGRDEANKI-AENND 108
           +QL E TR LQKD++    +  AM +++ K++  L    + E D   +D  N + A +  
Sbjct: 32  QQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQD---QDLLNMVTALDTA 88

Query: 109 LLWMD-YHQKLVDQALLTMDTYLGQF----PDIKSRIAKRGRKLVDYDSARHHYESLQTA 163
           +  MD ++Q+ V+Q   T+   L +F    P +   + +R + L DY   +   E  +  
Sbjct: 89  MKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEKYEEK 148

Query: 164 KKKDE--AKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENF 221
           +K     AK+ +A EEL   ++ FE  N  L EE+P  + SR+ ++  +F+S+   +  +
Sbjct: 149 EKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRAQVVY 208

Query: 222 HKEMSKLNQNLNDVL 236
           + EM K+  +L+  L
Sbjct: 209 YSEMHKIFGDLSHQL 223


>gi|39930351 dynamin binding protein [Homo sapiens]
          Length = 1577

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 50/223 (22%), Positives = 90/223 (40%), Gaps = 18/223 (8%)

Query: 17   NVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKA-- 74
            ++ KK  R    +    G A + KDE FE+  +NF  Q        +DL  YL  ++   
Sbjct: 996  SIIKKSNRVSSHLKHLTGFAPQIKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHIRESA 1055

Query: 75   ---MHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDTYLG 131
               +  A    + C++  +  D    +  ++    +D L+ ++ ++     +  ++  L 
Sbjct: 1056 CVKVVAAVSMWDVCMERGHR-DLEQFERVHRYI--SDQLFTNFKERTERLVISPLNQLLS 1112

Query: 132  QFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEMNVD 191
             F      + KR  KL+D+ +     E L         K  K  EEL  A+  +E +N  
Sbjct: 1113 MFTGPHKLVQKRFDKLLDFYNCTERAEKL---------KDKKTLEELQSARNNYEALNAQ 1163

Query: 192  LQEELPSLWNSRVGFYVNTFQSIAGLEENF-HKEMSKLNQNLN 233
            L +ELP       G + N     A    +F H+ + +L   L+
Sbjct: 1164 LLDELPKFHQYAQGLFTNCVHGYAEAHCDFVHQALEQLKPLLS 1206



 Score = 35.8 bits (81), Expect = 0.082
 Identities = 25/81 (30%), Positives = 35/81 (43%), Gaps = 15/81 (18%)

Query: 371 SGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKES 430
           S +    +P   M + +A    +A   +EL  + GDV+ +I    P     GW  G    
Sbjct: 135 SQSALFQIPEYSMGQARALMGLSAQLDEELDFREGDVITIIGVPEP-----GWFEG---- 185

Query: 431 DWNQHKELEKCRGVFPENFTE 451
                 ELE  RG+FPE F E
Sbjct: 186 ------ELEGRRGIFPEGFVE 200



 Score = 31.2 bits (69), Expect = 2.0
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 15/68 (22%)

Query: 386 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF 445
           V+A  D+  + ++EL L  GD++ V+        DE WL+G KE             G F
Sbjct: 7   VRAIFDFCPSVSEELPLFVGDIIEVLAV-----VDEFWLLGKKED----------VTGQF 51

Query: 446 PENFTERV 453
           P +F E V
Sbjct: 52  PSSFVEIV 59


>gi|49640014 ubiquitin associated and SH3 domain containing, A short
           form [Homo sapiens]
          Length = 623

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 9/67 (13%)

Query: 386 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF 445
           ++A   Y   + DEL L  GD + V P Q  +E  EGW++G+ +           CRG  
Sbjct: 243 LRALFQYKPQNVDELTLSPGDYIFVDPTQQ-DEASEGWVIGISQR--------TGCRGFL 293

Query: 446 PENFTER 452
           PEN+T+R
Sbjct: 294 PENYTDR 300


>gi|9507221 ubiquitin associated and SH3 domain containing, A long
           form [Homo sapiens]
          Length = 661

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 9/67 (13%)

Query: 386 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF 445
           ++A   Y   + DEL L  GD + V P Q  +E  EGW++G+ +           CRG  
Sbjct: 281 LRALFQYKPQNVDELTLSPGDYIFVDPTQQ-DEASEGWVIGISQR--------TGCRGFL 331

Query: 446 PENFTER 452
           PEN+T+R
Sbjct: 332 PENYTDR 338


>gi|4826964 UV excision repair protein RAD23 homolog A [Homo
           sapiens]
          Length = 363

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 6/80 (7%)

Query: 277 GNKSPSPPDGSPAATPEIRVNHEPEPAGGAT---PGATLPKSPSQ---PAEASEVAGGTQ 330
           G  + +PP+ SP A PE   +  P P  G +   P A   KSPS+   P  + E   G+ 
Sbjct: 82  GQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAAREDKSPSEESAPTTSPESVSGSV 141

Query: 331 PAAGAQEPGETAASEAASSS 350
           P++G+    E AAS   + S
Sbjct: 142 PSSGSSGREEDAASTLVTGS 161


>gi|115527120 nebulin [Homo sapiens]
          Length = 6669

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 38/157 (24%), Positives = 63/157 (40%), Gaps = 39/157 (24%)

Query: 314  KSPSQPAEASEVAGGTQPAAGAQEPGE--------------TAASEAASSSLP---AVVV 356
            +  S+ A A  ++GG + +  ++ P                TA   A ++ LP   +  V
Sbjct: 6535 REQSRSASALSISGGEEKSEHSEAPDHHLSTYSDGGVFAVSTAYKHAKTTELPQQRSSSV 6594

Query: 357  ETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNP 416
             T   TV+      S AG++          +A +DY A D DE+  K GD ++     N 
Sbjct: 6595 ATQQTTVSSIPSHPSTAGKI---------FRAMYDYMAADADEVSFKDGDAII-----NV 6640

Query: 417  EEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 453
            +  DEGW+ G  +             G+ P N+ E +
Sbjct: 6641 QAIDEGWMYGTVQRTGR--------TGMLPANYVEAI 6669


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 37/112 (33%), Positives = 46/112 (41%), Gaps = 9/112 (8%)

Query: 273 APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEV--AGGTQ 330
           A A G    +P +G+P A PE      P PAG A PG   P+ P  P+    +  AG   
Sbjct: 68  AGAAGAGPAAPAEGAPGAAPE------PPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAP 121

Query: 331 PAAGAQEPGE-TAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPG 381
           PAA  + P E +A S A   +  AV     PA        G  A      PG
Sbjct: 122 PAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPG 173



 Score = 37.4 bits (85), Expect = 0.028
 Identities = 34/109 (31%), Positives = 43/109 (39%), Gaps = 18/109 (16%)

Query: 273 APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAGGTQPA 332
           APA  +   +P   +PAA P       P PA      ATL + P  PA     A    P 
Sbjct: 251 APAAPSPPAAPAPAAPAAAPP-----PPPPAP-----ATLARPPGHPAGPPTAAPAVPPP 300

Query: 333 AGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPG 381
           A AQ  G   A+ A + +         PA V+G  + G GA      PG
Sbjct: 301 AAAQNGGSAGAAPAPAPAAGG------PAGVSG--QPGPGAAAAAPAPG 341



 Score = 32.7 bits (73), Expect = 0.70
 Identities = 36/132 (27%), Positives = 44/132 (33%), Gaps = 31/132 (23%)

Query: 273 APAKGNKSPS----PPDGSPAATPEIRVNH--------EPEPAGGATPGATLPKSPSQPA 320
           APA   + P     PP  +PA  P     +         P PA G   G +    P   A
Sbjct: 276 APATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAA 335

Query: 321 EA----------SEVAGGTQPAA---GAQEPGETAASEAASSSL------PAVVVETFPA 361
            A            V     PAA    A  P  TAAS     ++      PA V    P 
Sbjct: 336 AAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPG 395

Query: 362 TVNGTVEGGSGA 373
           T  G  +G +GA
Sbjct: 396 TPTGLPKGAAGA 407


>gi|40807452 peroxisome proliferator-activated receptor gamma,
           coactivator-related 1 [Homo sapiens]
          Length = 1664

 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 40/153 (26%), Positives = 62/153 (40%), Gaps = 9/153 (5%)

Query: 232 LNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAAT 291
           + +V+  L+ + G++  T +A+PR  S   S  RR++    A  +  +SP PP G   + 
Sbjct: 726 VKEVVDSLKIESGTSATTHEARPRPLS--LSEYRRRRQQRQAETE-ERSPQPPTGKWPSL 782

Query: 292 PEIRVNHEPEPAGGATPG----ATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAA 347
           PE        P     P       L +SP  P E   V  G  PA+ + EP    +   A
Sbjct: 783 PETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEP--PVSKPVA 840

Query: 348 SSSLPAVVVETFPATVNGTVEGGSGAGRLDLPP 380
           SS    V  +  P     +    S +  +  PP
Sbjct: 841 SSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPP 873


>gi|7662162 ALEX2 protein [Homo sapiens]
          Length = 632

 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 31/113 (27%), Positives = 43/113 (38%), Gaps = 4/113 (3%)

Query: 273 APAKGNKSPSPPDGSPAATPEIRVNHEPEPA----GGATPGATLPKSPSQPAEASEVAGG 328
           AP  G         +PA     +V   P  A        PG  +P   + P E +E  G 
Sbjct: 140 APPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGPGV 199

Query: 329 TQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPG 381
             P   A+ PG  + +EAA + +PA        T      G SG+ R  + PG
Sbjct: 200 AAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPG 252


>gi|29540562 ALEX2 protein [Homo sapiens]
          Length = 632

 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 31/113 (27%), Positives = 43/113 (38%), Gaps = 4/113 (3%)

Query: 273 APAKGNKSPSPPDGSPAATPEIRVNHEPEPA----GGATPGATLPKSPSQPAEASEVAGG 328
           AP  G         +PA     +V   P  A        PG  +P   + P E +E  G 
Sbjct: 140 APPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGPGV 199

Query: 329 TQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPG 381
             P   A+ PG  + +EAA + +PA        T      G SG+ R  + PG
Sbjct: 200 AAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPG 252


>gi|219842343 glutamate receptor, metabotropic 5 isoform a precursor
            [Homo sapiens]
          Length = 1212

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 35/122 (28%), Positives = 50/122 (40%), Gaps = 14/122 (11%)

Query: 258  SKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPS 317
            S + +R     +  N+      +PSP  G+P  +  +       P     P      +  
Sbjct: 1062 SSVVTRFTANISELNSMMLSTAAPSPGVGAPLCSSYLI------PKEIQLPTTMTTFAEI 1115

Query: 318  QPAEASEVAGGTQPAAGAQEPGETA--------ASEAASSSLPAVVVETFPATVNGTVEG 369
            QP  A EV GG QPAAGAQ  G+ A         + AA   L  +V  T P+    +V+ 
Sbjct: 1116 QPLPAIEVTGGAQPAAGAQAAGDAARESPAAGPEAAAAKPDLEELVALTPPSPFRDSVDS 1175

Query: 370  GS 371
            GS
Sbjct: 1176 GS 1177


>gi|4504143 glutamate receptor, metabotropic 5 isoform b precursor
            [Homo sapiens]
          Length = 1180

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 35/122 (28%), Positives = 50/122 (40%), Gaps = 14/122 (11%)

Query: 258  SKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPS 317
            S + +R     +  N+      +PSP  G+P  +  +       P     P      +  
Sbjct: 1030 SSVVTRFTANISELNSMMLSTAAPSPGVGAPLCSSYLI------PKEIQLPTTMTTFAEI 1083

Query: 318  QPAEASEVAGGTQPAAGAQEPGETA--------ASEAASSSLPAVVVETFPATVNGTVEG 369
            QP  A EV GG QPAAGAQ  G+ A         + AA   L  +V  T P+    +V+ 
Sbjct: 1084 QPLPAIEVTGGAQPAAGAQAAGDAARESPAAGPEAAAAKPDLEELVALTPPSPFRDSVDS 1143

Query: 370  GS 371
            GS
Sbjct: 1144 GS 1145


>gi|241982780 programmed cell death 6 interacting protein isoform 2
           [Homo sapiens]
          Length = 873

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 52/226 (23%), Positives = 88/226 (38%), Gaps = 34/226 (15%)

Query: 173 KAEEELIKAQKVFEEMNVDLQE-ELPSLWNSRVGFYVNTFQSIAGLEENFH------KEM 225
           K +E L K + + + + V  QE       N+         +++A   +NF       KE 
Sbjct: 619 KVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVELVANLKEG 678

Query: 226 SKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSK-LFSRLRRKKNSDNAPAK-------G 277
           +K    L ++LV  + +     F  K +  +  K L   + R+ ++ + P         G
Sbjct: 679 TKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPTPAYQSSPAG 738

Query: 278 NKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEA-SEVAGGTQPAAGAQ 336
             +P+PP  +P   P  +    P+P     P   LP + +  A A S V  GT   A +Q
Sbjct: 739 GHAPTPPTPAPRTMPPTK----PQPPARPPP-PVLPANRAPSATAPSPVGAGTAAPAPSQ 793

Query: 337 EPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGF 382
            PG     +A     P     T+P        G  G  ++ +P G+
Sbjct: 794 TPGSAPPPQAQGPPYP-----TYP--------GYPGYCQMPMPMGY 826


>gi|22027538 programmed cell death 6 interacting protein isoform 1
           [Homo sapiens]
          Length = 868

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 52/226 (23%), Positives = 88/226 (38%), Gaps = 34/226 (15%)

Query: 173 KAEEELIKAQKVFEEMNVDLQE-ELPSLWNSRVGFYVNTFQSIAGLEENFH------KEM 225
           K +E L K + + + + V  QE       N+         +++A   +NF       KE 
Sbjct: 614 KVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVELVANLKEG 673

Query: 226 SKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSK-LFSRLRRKKNSDNAPAK-------G 277
           +K    L ++LV  + +     F  K +  +  K L   + R+ ++ + P         G
Sbjct: 674 TKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPTPAYQSSPAG 733

Query: 278 NKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEA-SEVAGGTQPAAGAQ 336
             +P+PP  +P   P  +    P+P     P   LP + +  A A S V  GT   A +Q
Sbjct: 734 GHAPTPPTPAPRTMPPTK----PQPPARPPP-PVLPANRAPSATAPSPVGAGTAAPAPSQ 788

Query: 337 EPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGF 382
            PG     +A     P     T+P        G  G  ++ +P G+
Sbjct: 789 TPGSAPPPQAQGPPYP-----TYP--------GYPGYCQMPMPMGY 821


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 57/267 (21%), Positives = 111/267 (41%), Gaps = 30/267 (11%)

Query: 11   AGKIASNVQKKLTRAQEKVLQKLGKAD-ETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYL 69
            A +   N + +L    + +LQ  GK D E K ++ E  +Q    +  EG R++ +L   +
Sbjct: 1218 AKQTLENERGELANEVKVLLQ--GKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKV 1275

Query: 70   ASVKAMHEASKKL---NECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTM 126
              ++   +    L   ++        D+   +  +++ +  +LL  +  QKL      ++
Sbjct: 1276 TKLQVELDNVTGLLSQSDSKSSKLTKDFSALE--SQLQDTQELLQEENRQKL------SL 1327

Query: 127  DTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFE 186
             T L Q  D K+   ++   L + + A+H+ E          A + K  E+ +   +  E
Sbjct: 1328 STKLKQVEDEKNSFREQ---LEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAE 1384

Query: 187  EMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSN 246
            E+   LQ++L  L            +      +   K  ++L Q L+D+LV L+ Q  S 
Sbjct: 1385 EVKRKLQKDLEGL--------SQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQS- 1435

Query: 247  TFTVKAQPRKKSKLFSRLRRKKNSDNA 273
                     KK K F +L  ++ + +A
Sbjct: 1436 ----ACNLEKKQKKFDQLLAEEKTISA 1458



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 20/137 (14%)

Query: 136  IKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEMNVDLQEE 195
            ++  I +   +L + +SAR   + LQ  K   EAK+ K EEE    Q + E+ N  L +E
Sbjct: 941  MQQNIQELEEQLEEEESAR---QKLQLEKVTTEAKLKKLEEE----QIILEDQNCKLAKE 993

Query: 196  LPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPR 255
               L +    F  N  +     EE   K ++KL      ++  LE++       ++ + +
Sbjct: 994  KKLLEDRIAEFTTNLTE-----EEEKSKSLAKLKNKHEAMITDLEER-------LRREEK 1041

Query: 256  KKSKLFSRLRRKKNSDN 272
            ++ +L  + RRK   D+
Sbjct: 1042 QRQEL-EKTRRKLEGDS 1057



 Score = 33.9 bits (76), Expect = 0.31
 Identities = 54/264 (20%), Positives = 111/264 (42%), Gaps = 35/264 (13%)

Query: 13   KIASNVQKKLTRAQ-EKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQ--------- 62
            K+   V  +  +AQ E+ LQ   +  E K +Q  + V+    +L +  + +         
Sbjct: 1555 KLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKK 1614

Query: 63   -----KDLRTYLAS--------VKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDL 109
                 KDL  ++ S        +K + +   ++ +C++E+ +      +   +  EN   
Sbjct: 1615 LEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKK 1674

Query: 110  LWMDYHQKLVDQALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKD-E 168
            L      K ++  ++ +   L      K +  +   +L D  +      +L   +K+  E
Sbjct: 1675 L------KSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLE 1728

Query: 169  AKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKL 228
            A+IA+ EEEL + Q   E +N  L++   +L   ++   +N  +S A   EN  +++ + 
Sbjct: 1729 ARIAQLEEELEEEQGNTELINDRLKK--ANLQIDQINTDLNLERSHAQKNENARQQLERQ 1786

Query: 229  NQNLNDVLVGLEKQHGSNTFTVKA 252
            N+ L    V L++  G+     KA
Sbjct: 1787 NKELK---VKLQEMEGTVKSKYKA 1807


>gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo
           sapiens]
          Length = 384

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 37/117 (31%), Positives = 49/117 (41%), Gaps = 11/117 (9%)

Query: 262 SRLRRKKNSDNAPAKGNKSPSP-PDGS--PAATP-EIRVNHEPEPAGGATPGATLPKSPS 317
           SRL R   S  + A    S +P PD    PAA P   R    P  +G  T  + +P  PS
Sbjct: 52  SRLERGTFSPESAAGTEVSGAPHPDSRTRPAARPPHPRTRSPPGRSGSGTTFSAVPPRPS 111

Query: 318 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAG 374
           Q    S +    +PAA    PG ++A  + + + P     T P        GGSG G
Sbjct: 112 QHQSGSRL----RPAAPGPRPGCSSARASPAPAAPQAAARTAPGR---AASGGSGPG 161


>gi|239749199 PREDICTED: hypothetical protein XP_002346952 [Homo
           sapiens]
          Length = 209

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 37/117 (31%), Positives = 49/117 (41%), Gaps = 11/117 (9%)

Query: 262 SRLRRKKNSDNAPAKGNKSPSP-PDGS--PAATP-EIRVNHEPEPAGGATPGATLPKSPS 317
           SRL R   S  + A    S +P PD    PAA P   R    P  +G  T  + +P  PS
Sbjct: 52  SRLERGTFSPESAAGTEVSGAPHPDSRTRPAARPPHPRTRSPPGRSGSGTTFSAVPPRPS 111

Query: 318 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAG 374
           Q    S +    +PAA    PG ++A  + + + P     T P        GGSG G
Sbjct: 112 QHQSGSRL----RPAAPGPRPGCSSARASPAPAAPQAAARTAPGR---AASGGSGPG 161


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.127    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,753,756
Number of Sequences: 37866
Number of extensions: 997143
Number of successful extensions: 8217
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 115
Number of HSP's successfully gapped in prelim test: 712
Number of HSP's that attempted gapping in prelim test: 6576
Number of HSP's gapped (non-prelim): 2074
length of query: 454
length of database: 18,247,518
effective HSP length: 106
effective length of query: 348
effective length of database: 14,233,722
effective search space: 4953335256
effective search space used: 4953335256
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.