BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|47174861 peter pan homolog [Homo sapiens] (473 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|47174861 peter pan homolog [Homo sapiens] 938 0.0 gi|99028871 PPAN-P2RY11 protein [Homo sapiens] 845 0.0 gi|153791630 bromodomain and WD repeat domain containing 3 [Homo... 43 5e-04 gi|7661952 squamous cell carcinoma antigen recognized by T cells... 43 7e-04 gi|157676331 hyaluronan binding protein 4 [Homo sapiens] 42 0.001 gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002 gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 41 0.002 gi|41322923 plectin 1 isoform 11 [Homo sapiens] 41 0.003 gi|41322914 plectin 1 isoform 10 [Homo sapiens] 41 0.003 gi|41322919 plectin 1 isoform 8 [Homo sapiens] 41 0.003 gi|41322910 plectin 1 isoform 7 [Homo sapiens] 41 0.003 gi|41322916 plectin 1 isoform 6 [Homo sapiens] 41 0.003 gi|41322908 plectin 1 isoform 3 [Homo sapiens] 41 0.003 gi|41322912 plectin 1 isoform 2 [Homo sapiens] 41 0.003 gi|47607492 plectin 1 isoform 1 [Homo sapiens] 41 0.003 gi|10947135 ATP-binding cassette, sub-family F, member 1 isoform... 40 0.004 gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform... 40 0.004 gi|166795264 AE binding protein 2 isoform b [Homo sapiens] 40 0.004 gi|52426743 cisplatin resistance-associated overexpressed protei... 40 0.004 gi|19923485 cisplatin resistance-associated overexpressed protei... 40 0.004 gi|166795262 AE binding protein 2 isoform a [Homo sapiens] 40 0.004 gi|22758136 MAP7 domain containing 2 [Homo sapiens] 40 0.004 gi|221219020 NYD-SP11 protein [Homo sapiens] 40 0.005 gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi... 40 0.005 gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 ... 40 0.005 gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens] 40 0.005 gi|213385278 TNF receptor-associated factor 3 interacting protei... 39 0.008 gi|20070262 TNF receptor-associated factor 3 interacting protein... 39 0.008 gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 39 0.008 gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 39 0.013 >gi|47174861 peter pan homolog [Homo sapiens] Length = 473 Score = 938 bits (2424), Expect = 0.0 Identities = 473/473 (100%), Positives = 473/473 (100%) Query: 1 MGQSGRSRHQKRARAQAQLRNLEAYAANPHSFVFTRGCTGRNIRQLSLDVRRVMEPLTAS 60 MGQSGRSRHQKRARAQAQLRNLEAYAANPHSFVFTRGCTGRNIRQLSLDVRRVMEPLTAS Sbjct: 1 MGQSGRSRHQKRARAQAQLRNLEAYAANPHSFVFTRGCTGRNIRQLSLDVRRVMEPLTAS 60 Query: 61 RLQVRKKNSLKDCVAVAGPLGVTHFLILSKTETNVYFKLMRLPGGPTLTFQVKKYSLVRD 120 RLQVRKKNSLKDCVAVAGPLGVTHFLILSKTETNVYFKLMRLPGGPTLTFQVKKYSLVRD Sbjct: 61 RLQVRKKNSLKDCVAVAGPLGVTHFLILSKTETNVYFKLMRLPGGPTLTFQVKKYSLVRD 120 Query: 121 VVSSLRRHRMHEQQFAHPPLLVLNSFGPHGMHVKLMATMFQNLFPSINVHKVNLNTIKRC 180 VVSSLRRHRMHEQQFAHPPLLVLNSFGPHGMHVKLMATMFQNLFPSINVHKVNLNTIKRC Sbjct: 121 VVSSLRRHRMHEQQFAHPPLLVLNSFGPHGMHVKLMATMFQNLFPSINVHKVNLNTIKRC 180 Query: 181 LLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGAGLSES 240 LLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGAGLSES Sbjct: 181 LLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGAGLSES 240 Query: 241 EAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSF 300 EAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSF Sbjct: 241 EAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSF 300 Query: 301 VSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSD 360 VSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSD Sbjct: 301 VSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSD 360 Query: 361 EEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRK 420 EEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRK Sbjct: 361 EEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRK 420 Query: 421 RWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGGRGRGRGRPGKRVA 473 RWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGGRGRGRGRPGKRVA Sbjct: 421 RWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGGRGRGRGRPGKRVA 473 >gi|99028871 PPAN-P2RY11 protein [Homo sapiens] Length = 794 Score = 845 bits (2182), Expect = 0.0 Identities = 433/448 (96%), Positives = 434/448 (96%), Gaps = 2/448 (0%) Query: 1 MGQSGRSRHQKRARAQAQLRNLEAYAANPHSFVFTRGCTGRNIRQLSLDVRRVMEPLTAS 60 MGQSGRSRHQKRARAQAQLRNLEAYAANPHSFVFTRGCTGRNIRQLSLDVRRVMEPLTAS Sbjct: 1 MGQSGRSRHQKRARAQAQLRNLEAYAANPHSFVFTRGCTGRNIRQLSLDVRRVMEPLTAS 60 Query: 61 RLQVRKKNSLKDCVAVAGPLGVTHFLILSKTETNVYFKLMRLPGGPTLTFQVKKYSLVRD 120 RLQVRKKNSLKDCVAVAGPLGVTHFLILSKTETNVYFKLMRLPGGPTLTFQVKKYSLVRD Sbjct: 61 RLQVRKKNSLKDCVAVAGPLGVTHFLILSKTETNVYFKLMRLPGGPTLTFQVKKYSLVRD 120 Query: 121 VVSSLRRHRMHEQQFAHPPLLVLNSFGPHGMHVKLMATMFQNLFPSINVHKVNLNTIKRC 180 VVSSLRRHRMHEQQFAHPPLLVLNSFGPHGMHVKLMATMFQNLFPSINVHKVNLNTIKRC Sbjct: 121 VVSSLRRHRMHEQQFAHPPLLVLNSFGPHGMHVKLMATMFQNLFPSINVHKVNLNTIKRC 180 Query: 181 LLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGAGLSES 240 LLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGAGLSES Sbjct: 181 LLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGAGLSES 240 Query: 241 EAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSF 300 EAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSF Sbjct: 241 EAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSF 300 Query: 301 VSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSD 360 VSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSD Sbjct: 301 VSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSD 360 Query: 361 EEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRK 420 EEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRK Sbjct: 361 EEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRK 420 Query: 421 RWEMDRGRGRLCDQKF-PKTKDKSQGAQ 447 RWEMDRG + C F DK G Q Sbjct: 421 RWEMDRG-AKSCPANFLAAADDKLSGFQ 447 >gi|153791630 bromodomain and WD repeat domain containing 3 [Homo sapiens] Length = 1802 Score = 43.1 bits (100), Expect = 5e-04 Identities = 37/136 (27%), Positives = 55/136 (40%), Gaps = 13/136 (9%) Query: 337 QEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGE 396 +E++E K L + +G S S S + S D + D D +Y Sbjct: 1590 KEKKETKEKSHLSTSESGELGSSLSSESTCGSDSDSESTSRTDQDYVDGDHDY------- 1642 Query: 397 APSEDLFPEAKQKR-LAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQGAQAR-RGPRG 454 F + + KR L K G ++ W+ GR ++ + +G R RG RG Sbjct: 1643 ----SKFIQTRPKRKLRKQHGNGKRNWKTRGTGGRGRWGRWGRWSRGGRGRGGRGRGSRG 1698 Query: 455 ASRDGGRGRGRGRPGK 470 G RGRGRGR G+ Sbjct: 1699 RGGGGTRGRGRGRGGR 1714 >gi|7661952 squamous cell carcinoma antigen recognized by T cells 3 [Homo sapiens] Length = 963 Score = 42.7 bits (99), Expect = 7e-04 Identities = 39/170 (22%), Positives = 68/170 (40%), Gaps = 30/170 (17%) Query: 264 RAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKTEEELQAI----LEAKEKKL 319 +A AV+ T P +++ E + V KTE L + ++A EK+ Sbjct: 529 KALHRAVQCTSDYPEHVCEVLLTMERTEGSLEDWDIAVQKTETRLARVNEQRMKAAEKEA 588 Query: 320 RLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELGEDD 379 L Q + + Q + + E++ +KK + G +K DE+ E G+D+ Sbjct: 589 ALVQQEEEKAEQRKRARAEKKALKKKKKIRGPEKRGADEDDEK-----------EWGDDE 637 Query: 380 DEQ---------------EDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKS 414 +EQ E ++E G+ + D+ P +KQK A S Sbjct: 638 EEQPSKRRRVENSIPAAGETQNVEVAAGPAGKCAAVDVEPPSKQKEKAAS 687 >gi|157676331 hyaluronan binding protein 4 [Homo sapiens] Length = 413 Score = 42.4 bits (98), Expect = 0.001 Identities = 46/197 (23%), Positives = 75/197 (38%), Gaps = 22/197 (11%) Query: 293 GKVMFHSFVSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRK------- 345 G M SF +L+ + + + + ++ Q +QRK+ A Sbjct: 13 GAAMQESFGCVVANRFHQLLDDESDPFDILREAERRRQQQLQRKRRDEAAAAAGAGPRGG 72 Query: 346 KSLEGMKKARVGG-----SDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSE 400 +S G R G S +E +P+ A Q + + ++ Sbjct: 73 RSPAGASGHRAGAGGRRESQKERKSLPAPVAQRPDSPGGGLQAPGQKRTPRRGEQQGWND 132 Query: 401 DLFPEAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTK-----DKSQGAQARRGPRGA 455 PE +R + R+ + +E +R + +KFP K D+ + + R GPRG Sbjct: 133 SRGPEGMLERAERRSYREYRPYETER-QADFTAEKFPDEKPGDRFDRDRPLRGRGGPRG- 190 Query: 456 SRDGGRGRGRGRPGKRV 472 G RGRGRG PG RV Sbjct: 191 ---GMRGRGRGGPGNRV 204 >gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] Length = 819 Score = 41.6 bits (96), Expect = 0.002 Identities = 38/142 (26%), Positives = 60/142 (42%), Gaps = 17/142 (11%) Query: 336 KQEQREAHRKKSLEGMKKARVGGSDEEAS--GIPSRTASLELGEDDDEQEDDDIEYFCQA 393 K+ +R + R GG ++A+ G+ SR G+ Q+ + Sbjct: 323 KKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRG 382 Query: 394 VGEAPSEDLFPEAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQGAQA--RRG 451 G+ EAK++ GRK+ RW+ R R QK P K + G++ RRG Sbjct: 383 GGDKKG---LREAKRR----GDGRKKPRWQNPRRRA----QKAPAAKPRGGGSKKPRRRG 431 Query: 452 PRGASRDGGRGRGRG--RPGKR 471 P+ A GG+ R G +P +R Sbjct: 432 PKAAKSRGGKSRSGGGKKPRRR 453 Score = 29.6 bits (65), Expect = 6.2 Identities = 35/140 (25%), Positives = 52/140 (37%), Gaps = 13/140 (9%) Query: 335 RKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAV 394 R ++ R +K + G KK R A+G +R A + + Sbjct: 119 RGRKPRRRGQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQG-------- 170 Query: 395 GEAPSEDLFPEAKQKRLAKSP---GRKRKRWEMDRGRGRLCDQKFPKTKDKSQGAQARRG 451 GE P + AK R K P G K + E +GR R +F KT+ + R Sbjct: 171 GEKPQKAAAAGAKS-RSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRRPK 229 Query: 452 PRGASRDGGRGRGRGRPGKR 471 P RG G+ +P K+ Sbjct: 230 PAAGGAKSRRGGGK-KPQKQ 248 >gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo sapiens] Length = 600 Score = 41.2 bits (95), Expect = 0.002 Identities = 38/156 (24%), Positives = 67/156 (42%), Gaps = 3/156 (1%) Query: 315 KEKKLRLKAQRQAQQAQNVQRKQE-QREAHRKKSLEGMK-KARVGGSDEEASGIPSRTAS 372 +E++ K QR+ ++ + +RK+E QRE R++ + + R + E R Sbjct: 279 RERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDRE 338 Query: 373 LELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRKRWEMDRGRGRLC 432 E Q + D E Q E + +++ + R+R+ E DR R R Sbjct: 339 KERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQK 398 Query: 433 DQKFPKTKDK-SQGAQARRGPRGASRDGGRGRGRGR 467 +++ KD+ Q ++ R R+ RGR RGR Sbjct: 399 ERERQTEKDRDGQRETEKQREREKDRESERGRERGR 434 Score = 36.2 bits (82), Expect = 0.066 Identities = 42/174 (24%), Positives = 73/174 (41%), Gaps = 17/174 (9%) Query: 305 EEELQAILEAKEKKLRLKAQRQAQQAQNVQR-------KQEQREAHRKKSLEGMKKARVG 357 E E Q E KE++ + +RQ Q +N Q+ +QE+RE R++ E + R Sbjct: 148 ERERQRDAE-KERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS 206 Query: 358 GSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGR 417 E R E + + + D E Q E E +A+++R ++ Sbjct: 207 ERGRE------RERERETETETERKRQTDRERDRQRKTERERE---KQAERERASERETE 257 Query: 418 KRKRWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGGRGRGRGRPGKR 471 + K E +R R R D++ + + ++ + RR R + R R R R +R Sbjct: 258 RDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER 311 Score = 33.9 bits (76), Expect = 0.33 Identities = 38/172 (22%), Positives = 64/172 (37%), Gaps = 25/172 (14%) Query: 315 KEKKLRLKAQRQAQQAQNVQRKQEQ-REAHR-------KKSLEGMKKARVGGSDEEAS-- 364 KE++ + + R Q+ QR++E+ RE+ R ++ +G ++ R +D +A Sbjct: 398 KERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQ 457 Query: 365 --------GIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPG 416 P RTA + + D + I + + FP + + ++ Sbjct: 458 RKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRV 517 Query: 417 RKRKRWEM-------DRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGGR 461 R+RWE G GR F SQ GPR DG R Sbjct: 518 AGRRRWEPRLGEKRGQGGEGRRPSGGFGTENPLSQAPSVFPGPRYTPGDGKR 569 Score = 32.0 bits (71), Expect = 1.3 Identities = 30/163 (18%), Positives = 70/163 (42%), Gaps = 12/163 (7%) Query: 315 KEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLE 374 KE++ R + ++ ++ + ++ +++ HRK+ + R ++E R + Sbjct: 60 KERERRREKRQTERETDRKRERRREKDRHRKRD---RHRERQRDREKERERQTDRERDRQ 116 Query: 375 LGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRKRWEMDRGRGRLCDQ 434 ++ + Q++ + E + GE D + +++R + K + + DR R R ++ Sbjct: 117 REKERNRQKERERE--TEREGER-GRDRQTDGQRERERQRDAEKERERQTDRERQRQTER 173 Query: 435 KFPKTKDKSQGAQAR------RGPRGASRDGGRGRGRGRPGKR 471 K +++ + Q R R + D RGR R +R Sbjct: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERER 216 Score = 29.6 bits (65), Expect = 6.2 Identities = 36/171 (21%), Positives = 67/171 (39%), Gaps = 20/171 (11%) Query: 303 KTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEE 362 +TE E + + ++ R + + ++ Q + + +RE R K E + Sbjct: 217 ETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERER---------- 266 Query: 363 ASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRKRW 422 R + + + E++ D Q E E +Q+ + R RKR Sbjct: 267 -----DRDRDRDRRQKERERQTDRKR---QRRTERDRETERKRERQRERERERERNRKR- 317 Query: 423 EMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGGRGRGRGRPGKRVA 473 E +R R R +++ +D+ + + +R R D R R GR G+R A Sbjct: 318 ERERERERERERQRETERDREKERERKR-KRQTEMDRERNRQTGREGRRQA 367 >gi|41322923 plectin 1 isoform 11 [Homo sapiens] Length = 4547 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 11/147 (7%) Query: 247 DHNITELPQAVAG--RGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKT 304 DH+ L +A+A R + QQ A L M Q ++ ++ + E + + SF+S+ Sbjct: 2442 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM--QTVQQEQLLQETQALQQSFLSEK 2499 Query: 305 EEELQ--AILEAKEKKLRLKAQRQAQQAQNV----QRKQEQREAHRKKSLEGMKKARVGG 358 + LQ +E ++ KL Q + +AQ + QR+Q+Q E R++ + M++AR Sbjct: 2500 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-RR 2558 Query: 359 SDEEASGIPSRTASLELGEDDDEQEDD 385 E G+ + L+ E Q+++ Sbjct: 2559 QHEAEEGVRRKQEELQQLEQQRRQQEE 2585 Score = 31.6 bits (70), Expect = 1.6 Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 25/170 (14%) Query: 306 EELQAILEAKEKKLR---LKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS--- 359 EEL+ E E++LR ++ RQ Q A ++ + E K++ K A++ S Sbjct: 1539 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1598 Query: 360 --------DEEASGIPSRTASLELGEDDDEQE--------DDDIEYFCQAVGEAPSEDL- 402 EEA + A E ++ E+E ++ + QA A + L Sbjct: 1599 EHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLA 1658 Query: 403 -FPEAKQKRLAKSPGRKRKRWEMDRGRGR-LCDQKFPKTKDKSQGAQARR 450 KQK A+ R+R + E R R L +Q+ K + ++G +R Sbjct: 1659 QAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1708 Score = 31.6 bits (70), Expect = 1.6 Identities = 36/157 (22%), Positives = 75/157 (47%), Gaps = 15/157 (9%) Query: 299 SFVSKTEEELQAILE--AKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKK-SLEGMKKAR 355 SF KT + +++ E +LR +A+R+AQQ +R +E+ E ++ L+ + R Sbjct: 1584 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1643 Query: 356 VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415 + EE + S L + + E++ ++ E + G+A + +Q+ LA+ Sbjct: 1644 LRLQAEEVAQQKS------LAQAEAEKQKEEAEREARRRGKAEEQ----AVRQRELAEQE 1693 Query: 416 GRKRKRWEMDRGRGRL-CDQKFPKTK-DKSQGAQARR 450 K+++ + RL +Q+ + + + QG Q R+ Sbjct: 1694 LEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1730 Score = 31.2 bits (69), Expect = 2.1 Identities = 52/280 (18%), Positives = 110/280 (39%), Gaps = 16/280 (5%) Query: 176 TIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGA 235 T R L + + LD +K A+R ++ +E F +++++S+L A Sbjct: 2189 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE 2248 Query: 236 GLSESEAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKV 295 + + D D N Q A + A+++A RL+ +E + + + Sbjct: 2249 AENRALILRDKD-NTQRFLQEEAEKMKQVAEEAA-RLSVAAQEAARLRQLAEEDLAQQRA 2306 Query: 296 MFHSFVSKTEEELQAILEAKEKKLRLKAQRQA-----QQAQNVQRKQEQREAHRKKSLEG 350 + + +E++QA+ EA K + +Q +QA+ +Q +EQ + +G Sbjct: 2307 LAEKML---KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2363 Query: 351 MKKA------RVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFP 404 ++ R EA + R A + + E++ + +GE Sbjct: 2364 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2423 Query: 405 EAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQ 444 ++ L ++ +R++ + D R R + + K+K Q Sbjct: 2424 TQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQ 2463 Score = 30.0 bits (66), Expect = 4.8 Identities = 43/184 (23%), Positives = 72/184 (39%), Gaps = 43/184 (23%) Query: 215 QEKFPNMSRLQDISELLATGAGLSES--EAEPDGDHNITELPQAVAGRGNMRAQQSAVRL 272 Q++ RL ++ L L+E+ +A+ + EL Q R Q+ VR Sbjct: 1353 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--------RMQEEVVRR 1404 Query: 273 TEIGPRMTLQLIKVQEGVGEGKVMFHSFVS--------------KTEEELQAI---LEAK 315 E Q +QE + + + + + + EEE++ + LEA Sbjct: 1405 EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEAT 1464 Query: 316 EKK----------LRLKAQ------RQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS 359 E++ LR +A+ RQAQ+ R+Q Q E+ RK+ E +RV Sbjct: 1465 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1524 Query: 360 DEEA 363 E A Sbjct: 1525 AEAA 1528 >gi|41322914 plectin 1 isoform 10 [Homo sapiens] Length = 4551 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 11/147 (7%) Query: 247 DHNITELPQAVAG--RGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKT 304 DH+ L +A+A R + QQ A L M Q ++ ++ + E + + SF+S+ Sbjct: 2446 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM--QTVQQEQLLQETQALQQSFLSEK 2503 Query: 305 EEELQ--AILEAKEKKLRLKAQRQAQQAQNV----QRKQEQREAHRKKSLEGMKKARVGG 358 + LQ +E ++ KL Q + +AQ + QR+Q+Q E R++ + M++AR Sbjct: 2504 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-RR 2562 Query: 359 SDEEASGIPSRTASLELGEDDDEQEDD 385 E G+ + L+ E Q+++ Sbjct: 2563 QHEAEEGVRRKQEELQQLEQQRRQQEE 2589 Score = 31.6 bits (70), Expect = 1.6 Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 25/170 (14%) Query: 306 EELQAILEAKEKKLR---LKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS--- 359 EEL+ E E++LR ++ RQ Q A ++ + E K++ K A++ S Sbjct: 1543 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1602 Query: 360 --------DEEASGIPSRTASLELGEDDDEQE--------DDDIEYFCQAVGEAPSEDL- 402 EEA + A E ++ E+E ++ + QA A + L Sbjct: 1603 EHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLA 1662 Query: 403 -FPEAKQKRLAKSPGRKRKRWEMDRGRGR-LCDQKFPKTKDKSQGAQARR 450 KQK A+ R+R + E R R L +Q+ K + ++G +R Sbjct: 1663 QAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1712 Score = 31.6 bits (70), Expect = 1.6 Identities = 36/157 (22%), Positives = 75/157 (47%), Gaps = 15/157 (9%) Query: 299 SFVSKTEEELQAILE--AKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKK-SLEGMKKAR 355 SF KT + +++ E +LR +A+R+AQQ +R +E+ E ++ L+ + R Sbjct: 1588 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1647 Query: 356 VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415 + EE + S L + + E++ ++ E + G+A + +Q+ LA+ Sbjct: 1648 LRLQAEEVAQQKS------LAQAEAEKQKEEAEREARRRGKAEEQ----AVRQRELAEQE 1697 Query: 416 GRKRKRWEMDRGRGRL-CDQKFPKTK-DKSQGAQARR 450 K+++ + RL +Q+ + + + QG Q R+ Sbjct: 1698 LEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1734 Score = 31.2 bits (69), Expect = 2.1 Identities = 52/280 (18%), Positives = 110/280 (39%), Gaps = 16/280 (5%) Query: 176 TIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGA 235 T R L + + LD +K A+R ++ +E F +++++S+L A Sbjct: 2193 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE 2252 Query: 236 GLSESEAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKV 295 + + D D N Q A + A+++A RL+ +E + + + Sbjct: 2253 AENRALILRDKD-NTQRFLQEEAEKMKQVAEEAA-RLSVAAQEAARLRQLAEEDLAQQRA 2310 Query: 296 MFHSFVSKTEEELQAILEAKEKKLRLKAQRQA-----QQAQNVQRKQEQREAHRKKSLEG 350 + + +E++QA+ EA K + +Q +QA+ +Q +EQ + +G Sbjct: 2311 LAEKML---KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2367 Query: 351 MKKA------RVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFP 404 ++ R EA + R A + + E++ + +GE Sbjct: 2368 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2427 Query: 405 EAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQ 444 ++ L ++ +R++ + D R R + + K+K Q Sbjct: 2428 TQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQ 2467 Score = 30.0 bits (66), Expect = 4.8 Identities = 43/184 (23%), Positives = 72/184 (39%), Gaps = 43/184 (23%) Query: 215 QEKFPNMSRLQDISELLATGAGLSES--EAEPDGDHNITELPQAVAGRGNMRAQQSAVRL 272 Q++ RL ++ L L+E+ +A+ + EL Q R Q+ VR Sbjct: 1357 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--------RMQEEVVRR 1408 Query: 273 TEIGPRMTLQLIKVQEGVGEGKVMFHSFVS--------------KTEEELQAI---LEAK 315 E Q +QE + + + + + + EEE++ + LEA Sbjct: 1409 EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEAT 1468 Query: 316 EKK----------LRLKAQ------RQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS 359 E++ LR +A+ RQAQ+ R+Q Q E+ RK+ E +RV Sbjct: 1469 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1528 Query: 360 DEEA 363 E A Sbjct: 1529 AEAA 1532 >gi|41322919 plectin 1 isoform 8 [Homo sapiens] Length = 4547 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 11/147 (7%) Query: 247 DHNITELPQAVAG--RGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKT 304 DH+ L +A+A R + QQ A L M Q ++ ++ + E + + SF+S+ Sbjct: 2442 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM--QTVQQEQLLQETQALQQSFLSEK 2499 Query: 305 EEELQ--AILEAKEKKLRLKAQRQAQQAQNV----QRKQEQREAHRKKSLEGMKKARVGG 358 + LQ +E ++ KL Q + +AQ + QR+Q+Q E R++ + M++AR Sbjct: 2500 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-RR 2558 Query: 359 SDEEASGIPSRTASLELGEDDDEQEDD 385 E G+ + L+ E Q+++ Sbjct: 2559 QHEAEEGVRRKQEELQQLEQQRRQQEE 2585 Score = 31.6 bits (70), Expect = 1.6 Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 25/170 (14%) Query: 306 EELQAILEAKEKKLR---LKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS--- 359 EEL+ E E++LR ++ RQ Q A ++ + E K++ K A++ S Sbjct: 1539 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1598 Query: 360 --------DEEASGIPSRTASLELGEDDDEQE--------DDDIEYFCQAVGEAPSEDL- 402 EEA + A E ++ E+E ++ + QA A + L Sbjct: 1599 EHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLA 1658 Query: 403 -FPEAKQKRLAKSPGRKRKRWEMDRGRGR-LCDQKFPKTKDKSQGAQARR 450 KQK A+ R+R + E R R L +Q+ K + ++G +R Sbjct: 1659 QAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1708 Score = 31.6 bits (70), Expect = 1.6 Identities = 36/157 (22%), Positives = 75/157 (47%), Gaps = 15/157 (9%) Query: 299 SFVSKTEEELQAILE--AKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKK-SLEGMKKAR 355 SF KT + +++ E +LR +A+R+AQQ +R +E+ E ++ L+ + R Sbjct: 1584 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1643 Query: 356 VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415 + EE + S L + + E++ ++ E + G+A + +Q+ LA+ Sbjct: 1644 LRLQAEEVAQQKS------LAQAEAEKQKEEAEREARRRGKAEEQ----AVRQRELAEQE 1693 Query: 416 GRKRKRWEMDRGRGRL-CDQKFPKTK-DKSQGAQARR 450 K+++ + RL +Q+ + + + QG Q R+ Sbjct: 1694 LEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1730 Score = 31.2 bits (69), Expect = 2.1 Identities = 52/280 (18%), Positives = 110/280 (39%), Gaps = 16/280 (5%) Query: 176 TIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGA 235 T R L + + LD +K A+R ++ +E F +++++S+L A Sbjct: 2189 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE 2248 Query: 236 GLSESEAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKV 295 + + D D N Q A + A+++A RL+ +E + + + Sbjct: 2249 AENRALILRDKD-NTQRFLQEEAEKMKQVAEEAA-RLSVAAQEAARLRQLAEEDLAQQRA 2306 Query: 296 MFHSFVSKTEEELQAILEAKEKKLRLKAQRQA-----QQAQNVQRKQEQREAHRKKSLEG 350 + + +E++QA+ EA K + +Q +QA+ +Q +EQ + +G Sbjct: 2307 LAEKML---KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2363 Query: 351 MKKA------RVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFP 404 ++ R EA + R A + + E++ + +GE Sbjct: 2364 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2423 Query: 405 EAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQ 444 ++ L ++ +R++ + D R R + + K+K Q Sbjct: 2424 TQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQ 2463 Score = 30.0 bits (66), Expect = 4.8 Identities = 43/184 (23%), Positives = 72/184 (39%), Gaps = 43/184 (23%) Query: 215 QEKFPNMSRLQDISELLATGAGLSES--EAEPDGDHNITELPQAVAGRGNMRAQQSAVRL 272 Q++ RL ++ L L+E+ +A+ + EL Q R Q+ VR Sbjct: 1353 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--------RMQEEVVRR 1404 Query: 273 TEIGPRMTLQLIKVQEGVGEGKVMFHSFVS--------------KTEEELQAI---LEAK 315 E Q +QE + + + + + + EEE++ + LEA Sbjct: 1405 EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEAT 1464 Query: 316 EKK----------LRLKAQ------RQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS 359 E++ LR +A+ RQAQ+ R+Q Q E+ RK+ E +RV Sbjct: 1465 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1524 Query: 360 DEEA 363 E A Sbjct: 1525 AEAA 1528 >gi|41322910 plectin 1 isoform 7 [Homo sapiens] Length = 4515 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 11/147 (7%) Query: 247 DHNITELPQAVAG--RGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKT 304 DH+ L +A+A R + QQ A L M Q ++ ++ + E + + SF+S+ Sbjct: 2410 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM--QTVQQEQLLQETQALQQSFLSEK 2467 Query: 305 EEELQ--AILEAKEKKLRLKAQRQAQQAQNV----QRKQEQREAHRKKSLEGMKKARVGG 358 + LQ +E ++ KL Q + +AQ + QR+Q+Q E R++ + M++AR Sbjct: 2468 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-RR 2526 Query: 359 SDEEASGIPSRTASLELGEDDDEQEDD 385 E G+ + L+ E Q+++ Sbjct: 2527 QHEAEEGVRRKQEELQQLEQQRRQQEE 2553 Score = 31.6 bits (70), Expect = 1.6 Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 25/170 (14%) Query: 306 EELQAILEAKEKKLR---LKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS--- 359 EEL+ E E++LR ++ RQ Q A ++ + E K++ K A++ S Sbjct: 1507 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1566 Query: 360 --------DEEASGIPSRTASLELGEDDDEQE--------DDDIEYFCQAVGEAPSEDL- 402 EEA + A E ++ E+E ++ + QA A + L Sbjct: 1567 EHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLA 1626 Query: 403 -FPEAKQKRLAKSPGRKRKRWEMDRGRGR-LCDQKFPKTKDKSQGAQARR 450 KQK A+ R+R + E R R L +Q+ K + ++G +R Sbjct: 1627 QAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1676 Score = 31.6 bits (70), Expect = 1.6 Identities = 36/157 (22%), Positives = 75/157 (47%), Gaps = 15/157 (9%) Query: 299 SFVSKTEEELQAILE--AKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKK-SLEGMKKAR 355 SF KT + +++ E +LR +A+R+AQQ +R +E+ E ++ L+ + R Sbjct: 1552 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1611 Query: 356 VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415 + EE + S L + + E++ ++ E + G+A + +Q+ LA+ Sbjct: 1612 LRLQAEEVAQQKS------LAQAEAEKQKEEAEREARRRGKAEEQ----AVRQRELAEQE 1661 Query: 416 GRKRKRWEMDRGRGRL-CDQKFPKTK-DKSQGAQARR 450 K+++ + RL +Q+ + + + QG Q R+ Sbjct: 1662 LEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1698 Score = 31.2 bits (69), Expect = 2.1 Identities = 52/280 (18%), Positives = 110/280 (39%), Gaps = 16/280 (5%) Query: 176 TIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGA 235 T R L + + LD +K A+R ++ +E F +++++S+L A Sbjct: 2157 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE 2216 Query: 236 GLSESEAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKV 295 + + D D N Q A + A+++A RL+ +E + + + Sbjct: 2217 AENRALILRDKD-NTQRFLQEEAEKMKQVAEEAA-RLSVAAQEAARLRQLAEEDLAQQRA 2274 Query: 296 MFHSFVSKTEEELQAILEAKEKKLRLKAQRQA-----QQAQNVQRKQEQREAHRKKSLEG 350 + + +E++QA+ EA K + +Q +QA+ +Q +EQ + +G Sbjct: 2275 LAEKML---KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2331 Query: 351 MKKA------RVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFP 404 ++ R EA + R A + + E++ + +GE Sbjct: 2332 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2391 Query: 405 EAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQ 444 ++ L ++ +R++ + D R R + + K+K Q Sbjct: 2392 TQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQ 2431 Score = 30.0 bits (66), Expect = 4.8 Identities = 43/184 (23%), Positives = 72/184 (39%), Gaps = 43/184 (23%) Query: 215 QEKFPNMSRLQDISELLATGAGLSES--EAEPDGDHNITELPQAVAGRGNMRAQQSAVRL 272 Q++ RL ++ L L+E+ +A+ + EL Q R Q+ VR Sbjct: 1321 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--------RMQEEVVRR 1372 Query: 273 TEIGPRMTLQLIKVQEGVGEGKVMFHSFVS--------------KTEEELQAI---LEAK 315 E Q +QE + + + + + + EEE++ + LEA Sbjct: 1373 EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEAT 1432 Query: 316 EKK----------LRLKAQ------RQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS 359 E++ LR +A+ RQAQ+ R+Q Q E+ RK+ E +RV Sbjct: 1433 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1492 Query: 360 DEEA 363 E A Sbjct: 1493 AEAA 1496 >gi|41322916 plectin 1 isoform 6 [Homo sapiens] Length = 4684 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 11/147 (7%) Query: 247 DHNITELPQAVAG--RGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKT 304 DH+ L +A+A R + QQ A L M Q ++ ++ + E + + SF+S+ Sbjct: 2579 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM--QTVQQEQLLQETQALQQSFLSEK 2636 Query: 305 EEELQ--AILEAKEKKLRLKAQRQAQQAQNV----QRKQEQREAHRKKSLEGMKKARVGG 358 + LQ +E ++ KL Q + +AQ + QR+Q+Q E R++ + M++AR Sbjct: 2637 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-RR 2695 Query: 359 SDEEASGIPSRTASLELGEDDDEQEDD 385 E G+ + L+ E Q+++ Sbjct: 2696 QHEAEEGVRRKQEELQQLEQQRRQQEE 2722 Score = 31.6 bits (70), Expect = 1.6 Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 25/170 (14%) Query: 306 EELQAILEAKEKKLR---LKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS--- 359 EEL+ E E++LR ++ RQ Q A ++ + E K++ K A++ S Sbjct: 1676 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1735 Query: 360 --------DEEASGIPSRTASLELGEDDDEQE--------DDDIEYFCQAVGEAPSEDL- 402 EEA + A E ++ E+E ++ + QA A + L Sbjct: 1736 EHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLA 1795 Query: 403 -FPEAKQKRLAKSPGRKRKRWEMDRGRGR-LCDQKFPKTKDKSQGAQARR 450 KQK A+ R+R + E R R L +Q+ K + ++G +R Sbjct: 1796 QAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1845 Score = 31.6 bits (70), Expect = 1.6 Identities = 36/157 (22%), Positives = 75/157 (47%), Gaps = 15/157 (9%) Query: 299 SFVSKTEEELQAILE--AKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKK-SLEGMKKAR 355 SF KT + +++ E +LR +A+R+AQQ +R +E+ E ++ L+ + R Sbjct: 1721 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1780 Query: 356 VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415 + EE + S L + + E++ ++ E + G+A + +Q+ LA+ Sbjct: 1781 LRLQAEEVAQQKS------LAQAEAEKQKEEAEREARRRGKAEEQ----AVRQRELAEQE 1830 Query: 416 GRKRKRWEMDRGRGRL-CDQKFPKTK-DKSQGAQARR 450 K+++ + RL +Q+ + + + QG Q R+ Sbjct: 1831 LEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1867 Score = 31.2 bits (69), Expect = 2.1 Identities = 52/280 (18%), Positives = 110/280 (39%), Gaps = 16/280 (5%) Query: 176 TIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGA 235 T R L + + LD +K A+R ++ +E F +++++S+L A Sbjct: 2326 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE 2385 Query: 236 GLSESEAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKV 295 + + D D N Q A + A+++A RL+ +E + + + Sbjct: 2386 AENRALILRDKD-NTQRFLQEEAEKMKQVAEEAA-RLSVAAQEAARLRQLAEEDLAQQRA 2443 Query: 296 MFHSFVSKTEEELQAILEAKEKKLRLKAQRQA-----QQAQNVQRKQEQREAHRKKSLEG 350 + + +E++QA+ EA K + +Q +QA+ +Q +EQ + +G Sbjct: 2444 LAEKML---KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2500 Query: 351 MKKA------RVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFP 404 ++ R EA + R A + + E++ + +GE Sbjct: 2501 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2560 Query: 405 EAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQ 444 ++ L ++ +R++ + D R R + + K+K Q Sbjct: 2561 TQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQ 2600 Score = 30.0 bits (66), Expect = 4.8 Identities = 43/184 (23%), Positives = 72/184 (39%), Gaps = 43/184 (23%) Query: 215 QEKFPNMSRLQDISELLATGAGLSES--EAEPDGDHNITELPQAVAGRGNMRAQQSAVRL 272 Q++ RL ++ L L+E+ +A+ + EL Q R Q+ VR Sbjct: 1490 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--------RMQEEVVRR 1541 Query: 273 TEIGPRMTLQLIKVQEGVGEGKVMFHSFVS--------------KTEEELQAI---LEAK 315 E Q +QE + + + + + + EEE++ + LEA Sbjct: 1542 EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEAT 1601 Query: 316 EKK----------LRLKAQ------RQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS 359 E++ LR +A+ RQAQ+ R+Q Q E+ RK+ E +RV Sbjct: 1602 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1661 Query: 360 DEEA 363 E A Sbjct: 1662 AEAA 1665 >gi|41322908 plectin 1 isoform 3 [Homo sapiens] Length = 4525 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 11/147 (7%) Query: 247 DHNITELPQAVAG--RGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKT 304 DH+ L +A+A R + QQ A L M Q ++ ++ + E + + SF+S+ Sbjct: 2420 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM--QTVQQEQLLQETQALQQSFLSEK 2477 Query: 305 EEELQ--AILEAKEKKLRLKAQRQAQQAQNV----QRKQEQREAHRKKSLEGMKKARVGG 358 + LQ +E ++ KL Q + +AQ + QR+Q+Q E R++ + M++AR Sbjct: 2478 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-RR 2536 Query: 359 SDEEASGIPSRTASLELGEDDDEQEDD 385 E G+ + L+ E Q+++ Sbjct: 2537 QHEAEEGVRRKQEELQQLEQQRRQQEE 2563 Score = 31.6 bits (70), Expect = 1.6 Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 25/170 (14%) Query: 306 EELQAILEAKEKKLR---LKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS--- 359 EEL+ E E++LR ++ RQ Q A ++ + E K++ K A++ S Sbjct: 1517 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1576 Query: 360 --------DEEASGIPSRTASLELGEDDDEQE--------DDDIEYFCQAVGEAPSEDL- 402 EEA + A E ++ E+E ++ + QA A + L Sbjct: 1577 EHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLA 1636 Query: 403 -FPEAKQKRLAKSPGRKRKRWEMDRGRGR-LCDQKFPKTKDKSQGAQARR 450 KQK A+ R+R + E R R L +Q+ K + ++G +R Sbjct: 1637 QAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1686 Score = 31.6 bits (70), Expect = 1.6 Identities = 36/157 (22%), Positives = 75/157 (47%), Gaps = 15/157 (9%) Query: 299 SFVSKTEEELQAILE--AKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKK-SLEGMKKAR 355 SF KT + +++ E +LR +A+R+AQQ +R +E+ E ++ L+ + R Sbjct: 1562 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1621 Query: 356 VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415 + EE + S L + + E++ ++ E + G+A + +Q+ LA+ Sbjct: 1622 LRLQAEEVAQQKS------LAQAEAEKQKEEAEREARRRGKAEEQ----AVRQRELAEQE 1671 Query: 416 GRKRKRWEMDRGRGRL-CDQKFPKTK-DKSQGAQARR 450 K+++ + RL +Q+ + + + QG Q R+ Sbjct: 1672 LEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1708 Score = 31.2 bits (69), Expect = 2.1 Identities = 52/280 (18%), Positives = 110/280 (39%), Gaps = 16/280 (5%) Query: 176 TIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGA 235 T R L + + LD +K A+R ++ +E F +++++S+L A Sbjct: 2167 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE 2226 Query: 236 GLSESEAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKV 295 + + D D N Q A + A+++A RL+ +E + + + Sbjct: 2227 AENRALILRDKD-NTQRFLQEEAEKMKQVAEEAA-RLSVAAQEAARLRQLAEEDLAQQRA 2284 Query: 296 MFHSFVSKTEEELQAILEAKEKKLRLKAQRQA-----QQAQNVQRKQEQREAHRKKSLEG 350 + + +E++QA+ EA K + +Q +QA+ +Q +EQ + +G Sbjct: 2285 LAEKML---KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2341 Query: 351 MKKA------RVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFP 404 ++ R EA + R A + + E++ + +GE Sbjct: 2342 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2401 Query: 405 EAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQ 444 ++ L ++ +R++ + D R R + + K+K Q Sbjct: 2402 TQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQ 2441 Score = 30.0 bits (66), Expect = 4.8 Identities = 43/184 (23%), Positives = 72/184 (39%), Gaps = 43/184 (23%) Query: 215 QEKFPNMSRLQDISELLATGAGLSES--EAEPDGDHNITELPQAVAGRGNMRAQQSAVRL 272 Q++ RL ++ L L+E+ +A+ + EL Q R Q+ VR Sbjct: 1331 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--------RMQEEVVRR 1382 Query: 273 TEIGPRMTLQLIKVQEGVGEGKVMFHSFVS--------------KTEEELQAI---LEAK 315 E Q +QE + + + + + + EEE++ + LEA Sbjct: 1383 EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEAT 1442 Query: 316 EKK----------LRLKAQ------RQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS 359 E++ LR +A+ RQAQ+ R+Q Q E+ RK+ E +RV Sbjct: 1443 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1502 Query: 360 DEEA 363 E A Sbjct: 1503 AEAA 1506 >gi|41322912 plectin 1 isoform 2 [Homo sapiens] Length = 4533 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 11/147 (7%) Query: 247 DHNITELPQAVAG--RGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKT 304 DH+ L +A+A R + QQ A L M Q ++ ++ + E + + SF+S+ Sbjct: 2428 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM--QTVQQEQLLQETQALQQSFLSEK 2485 Query: 305 EEELQ--AILEAKEKKLRLKAQRQAQQAQNV----QRKQEQREAHRKKSLEGMKKARVGG 358 + LQ +E ++ KL Q + +AQ + QR+Q+Q E R++ + M++AR Sbjct: 2486 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-RR 2544 Query: 359 SDEEASGIPSRTASLELGEDDDEQEDD 385 E G+ + L+ E Q+++ Sbjct: 2545 QHEAEEGVRRKQEELQQLEQQRRQQEE 2571 Score = 31.6 bits (70), Expect = 1.6 Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 25/170 (14%) Query: 306 EELQAILEAKEKKLR---LKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS--- 359 EEL+ E E++LR ++ RQ Q A ++ + E K++ K A++ S Sbjct: 1525 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1584 Query: 360 --------DEEASGIPSRTASLELGEDDDEQE--------DDDIEYFCQAVGEAPSEDL- 402 EEA + A E ++ E+E ++ + QA A + L Sbjct: 1585 EHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLA 1644 Query: 403 -FPEAKQKRLAKSPGRKRKRWEMDRGRGR-LCDQKFPKTKDKSQGAQARR 450 KQK A+ R+R + E R R L +Q+ K + ++G +R Sbjct: 1645 QAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1694 Score = 31.6 bits (70), Expect = 1.6 Identities = 36/157 (22%), Positives = 75/157 (47%), Gaps = 15/157 (9%) Query: 299 SFVSKTEEELQAILE--AKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKK-SLEGMKKAR 355 SF KT + +++ E +LR +A+R+AQQ +R +E+ E ++ L+ + R Sbjct: 1570 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1629 Query: 356 VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415 + EE + S L + + E++ ++ E + G+A + +Q+ LA+ Sbjct: 1630 LRLQAEEVAQQKS------LAQAEAEKQKEEAEREARRRGKAEEQ----AVRQRELAEQE 1679 Query: 416 GRKRKRWEMDRGRGRL-CDQKFPKTK-DKSQGAQARR 450 K+++ + RL +Q+ + + + QG Q R+ Sbjct: 1680 LEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1716 Score = 31.2 bits (69), Expect = 2.1 Identities = 52/280 (18%), Positives = 110/280 (39%), Gaps = 16/280 (5%) Query: 176 TIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGA 235 T R L + + LD +K A+R ++ +E F +++++S+L A Sbjct: 2175 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE 2234 Query: 236 GLSESEAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKV 295 + + D D N Q A + A+++A RL+ +E + + + Sbjct: 2235 AENRALILRDKD-NTQRFLQEEAEKMKQVAEEAA-RLSVAAQEAARLRQLAEEDLAQQRA 2292 Query: 296 MFHSFVSKTEEELQAILEAKEKKLRLKAQRQA-----QQAQNVQRKQEQREAHRKKSLEG 350 + + +E++QA+ EA K + +Q +QA+ +Q +EQ + +G Sbjct: 2293 LAEKML---KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2349 Query: 351 MKKA------RVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFP 404 ++ R EA + R A + + E++ + +GE Sbjct: 2350 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2409 Query: 405 EAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQ 444 ++ L ++ +R++ + D R R + + K+K Q Sbjct: 2410 TQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQ 2449 Score = 30.0 bits (66), Expect = 4.8 Identities = 43/184 (23%), Positives = 72/184 (39%), Gaps = 43/184 (23%) Query: 215 QEKFPNMSRLQDISELLATGAGLSES--EAEPDGDHNITELPQAVAGRGNMRAQQSAVRL 272 Q++ RL ++ L L+E+ +A+ + EL Q R Q+ VR Sbjct: 1339 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--------RMQEEVVRR 1390 Query: 273 TEIGPRMTLQLIKVQEGVGEGKVMFHSFVS--------------KTEEELQAI---LEAK 315 E Q +QE + + + + + + EEE++ + LEA Sbjct: 1391 EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEAT 1450 Query: 316 EKK----------LRLKAQ------RQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS 359 E++ LR +A+ RQAQ+ R+Q Q E+ RK+ E +RV Sbjct: 1451 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1510 Query: 360 DEEA 363 E A Sbjct: 1511 AEAA 1514 >gi|47607492 plectin 1 isoform 1 [Homo sapiens] Length = 4574 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 11/147 (7%) Query: 247 DHNITELPQAVAG--RGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKT 304 DH+ L +A+A R + QQ A L M Q ++ ++ + E + + SF+S+ Sbjct: 2469 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM--QTVQQEQLLQETQALQQSFLSEK 2526 Query: 305 EEELQ--AILEAKEKKLRLKAQRQAQQAQNV----QRKQEQREAHRKKSLEGMKKARVGG 358 + LQ +E ++ KL Q + +AQ + QR+Q+Q E R++ + M++AR Sbjct: 2527 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-RR 2585 Query: 359 SDEEASGIPSRTASLELGEDDDEQEDD 385 E G+ + L+ E Q+++ Sbjct: 2586 QHEAEEGVRRKQEELQQLEQQRRQQEE 2612 Score = 31.6 bits (70), Expect = 1.6 Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 25/170 (14%) Query: 306 EELQAILEAKEKKLR---LKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS--- 359 EEL+ E E++LR ++ RQ Q A ++ + E K++ K A++ S Sbjct: 1566 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1625 Query: 360 --------DEEASGIPSRTASLELGEDDDEQE--------DDDIEYFCQAVGEAPSEDL- 402 EEA + A E ++ E+E ++ + QA A + L Sbjct: 1626 EHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLA 1685 Query: 403 -FPEAKQKRLAKSPGRKRKRWEMDRGRGR-LCDQKFPKTKDKSQGAQARR 450 KQK A+ R+R + E R R L +Q+ K + ++G +R Sbjct: 1686 QAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1735 Score = 31.6 bits (70), Expect = 1.6 Identities = 36/157 (22%), Positives = 75/157 (47%), Gaps = 15/157 (9%) Query: 299 SFVSKTEEELQAILE--AKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKK-SLEGMKKAR 355 SF KT + +++ E +LR +A+R+AQQ +R +E+ E ++ L+ + R Sbjct: 1611 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1670 Query: 356 VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415 + EE + S L + + E++ ++ E + G+A + +Q+ LA+ Sbjct: 1671 LRLQAEEVAQQKS------LAQAEAEKQKEEAEREARRRGKAEEQ----AVRQRELAEQE 1720 Query: 416 GRKRKRWEMDRGRGRL-CDQKFPKTK-DKSQGAQARR 450 K+++ + RL +Q+ + + + QG Q R+ Sbjct: 1721 LEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1757 Score = 31.2 bits (69), Expect = 2.1 Identities = 52/280 (18%), Positives = 110/280 (39%), Gaps = 16/280 (5%) Query: 176 TIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGA 235 T R L + + LD +K A+R ++ +E F +++++S+L A Sbjct: 2216 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE 2275 Query: 236 GLSESEAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKV 295 + + D D N Q A + A+++A RL+ +E + + + Sbjct: 2276 AENRALILRDKD-NTQRFLQEEAEKMKQVAEEAA-RLSVAAQEAARLRQLAEEDLAQQRA 2333 Query: 296 MFHSFVSKTEEELQAILEAKEKKLRLKAQRQA-----QQAQNVQRKQEQREAHRKKSLEG 350 + + +E++QA+ EA K + +Q +QA+ +Q +EQ + +G Sbjct: 2334 LAEKML---KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2390 Query: 351 MKKA------RVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFP 404 ++ R EA + R A + + E++ + +GE Sbjct: 2391 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2450 Query: 405 EAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQ 444 ++ L ++ +R++ + D R R + + K+K Q Sbjct: 2451 TQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQ 2490 Score = 30.0 bits (66), Expect = 4.8 Identities = 43/184 (23%), Positives = 72/184 (39%), Gaps = 43/184 (23%) Query: 215 QEKFPNMSRLQDISELLATGAGLSES--EAEPDGDHNITELPQAVAGRGNMRAQQSAVRL 272 Q++ RL ++ L L+E+ +A+ + EL Q R Q+ VR Sbjct: 1380 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--------RMQEEVVRR 1431 Query: 273 TEIGPRMTLQLIKVQEGVGEGKVMFHSFVS--------------KTEEELQAI---LEAK 315 E Q +QE + + + + + + EEE++ + LEA Sbjct: 1432 EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEAT 1491 Query: 316 EKK----------LRLKAQ------RQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS 359 E++ LR +A+ RQAQ+ R+Q Q E+ RK+ E +RV Sbjct: 1492 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1551 Query: 360 DEEA 363 E A Sbjct: 1552 AEAA 1555 >gi|10947135 ATP-binding cassette, sub-family F, member 1 isoform b [Homo sapiens] Length = 807 Score = 40.4 bits (93), Expect = 0.004 Identities = 44/169 (26%), Positives = 77/169 (45%), Gaps = 34/169 (20%) Query: 286 VQEGVGEGKVMFHSFVSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRK 345 V++G + K+ F E+ QA E EK L+ K Q+Q QQ Q ++K++ R+ RK Sbjct: 28 VKKGKKDKKIKKTFFEELAVEDKQAGEE--EKVLKEKEQQQQQQQQQQKKKRDTRKGRRK 85 Query: 346 KS----------LEGMKKARVGGSDEE--------ASGIPSRTASL--ELGEDDDEQEDD 385 K +E +KK V SDEE G ++ ++ L +D E+E++ Sbjct: 86 KDVDDDGEEKELMERLKKLSVPTSDEEDEVPAPKPRGGKKTKGGNVFAALIQDQSEEEEE 145 Query: 386 DIEYFCQAVGEAPSEDLFPEAKQKRLAKS----PGRKRKRWEMDRGRGR 430 + ++ P + PE + A S P K K+ + ++ +G+ Sbjct: 146 EEKH--------PPKPAKPEKNRINKAVSEEQQPALKGKKGKEEKSKGK 186 >gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform a [Homo sapiens] Length = 845 Score = 40.4 bits (93), Expect = 0.004 Identities = 44/169 (26%), Positives = 77/169 (45%), Gaps = 34/169 (20%) Query: 286 VQEGVGEGKVMFHSFVSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRK 345 V++G + K+ F E+ QA E EK L+ K Q+Q QQ Q ++K++ R+ RK Sbjct: 28 VKKGKKDKKIKKTFFEELAVEDKQAGEE--EKVLKEKEQQQQQQQQQQKKKRDTRKGRRK 85 Query: 346 KS----------LEGMKKARVGGSDEE--------ASGIPSRTASL--ELGEDDDEQEDD 385 K +E +KK V SDEE G ++ ++ L +D E+E++ Sbjct: 86 KDVDDDGEEKELMERLKKLSVPTSDEEDEVPAPKPRGGKKTKGGNVFAALIQDQSEEEEE 145 Query: 386 DIEYFCQAVGEAPSEDLFPEAKQKRLAKS----PGRKRKRWEMDRGRGR 430 + ++ P + PE + A S P K K+ + ++ +G+ Sbjct: 146 EEKH--------PPKPAKPEKNRINKAVSEEQQPALKGKKGKEEKSKGK 186 >gi|166795264 AE binding protein 2 isoform b [Homo sapiens] Length = 517 Score = 40.4 bits (93), Expect = 0.004 Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 6/107 (5%) Query: 356 VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415 VGG + E PS ++ + GED+DE+EDD+ E + E E+ + L S Sbjct: 74 VGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEE----ESSAESLVGSS 129 Query: 416 GRKRKRWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGGRG 462 G G D +G + +GPRG+ GG G Sbjct: 130 GGSSSDETRSLSPGAASSSS--GDGDGKEGLEEPKGPRGSQGGGGGG 174 >gi|52426743 cisplatin resistance-associated overexpressed protein [Homo sapiens] Length = 432 Score = 40.4 bits (93), Expect = 0.004 Identities = 59/264 (22%), Positives = 109/264 (41%), Gaps = 57/264 (21%) Query: 204 VGASRGMKKLLQEKFPNMSRLQDISELLATGAGLSESEAEPDGDHNITELPQAVAGRGNM 263 V ++GM KL+++ L++ ELL + ES A + + E+ A G+ Sbjct: 152 VEEAQGMMKLVEQ-------LKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDA 204 Query: 264 RAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKTEEELQAILEAKEKKLRLKA 323 ++ R+ L+ Q +G K+ + V + +E+L+ E ++ RLK Sbjct: 205 QS------------RVDDHLMGKQH-MGYAKIK--ATVEELKEKLRKRTEEPDRDERLKK 249 Query: 324 QRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELGEDDDEQE 383 ++Q ++ + +R++E+ E RK+ E ++ + D E SR+ S D Sbjct: 250 EKQEREEREKEREREREERERKRRREEEEREKERARDRERRK-RSRSRSRHSSRTSD--- 305 Query: 384 DDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKS 443 +R ++S KR R +R R R D++ ++ D+S Sbjct: 306 -------------------------RRCSRSRDHKRSR-SRERRRSRSRDRRRSRSHDRS 339 Query: 444 QGAQARRGPRGASRDGGRGRGRGR 467 + R R SRD R + R R Sbjct: 340 E-----RKHRSRSRDRRRSKSRDR 358 >gi|19923485 cisplatin resistance-associated overexpressed protein [Homo sapiens] Length = 432 Score = 40.4 bits (93), Expect = 0.004 Identities = 59/264 (22%), Positives = 109/264 (41%), Gaps = 57/264 (21%) Query: 204 VGASRGMKKLLQEKFPNMSRLQDISELLATGAGLSESEAEPDGDHNITELPQAVAGRGNM 263 V ++GM KL+++ L++ ELL + ES A + + E+ A G+ Sbjct: 152 VEEAQGMMKLVEQ-------LKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDA 204 Query: 264 RAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKTEEELQAILEAKEKKLRLKA 323 ++ R+ L+ Q +G K+ + V + +E+L+ E ++ RLK Sbjct: 205 QS------------RVDDHLMGKQH-MGYAKIK--ATVEELKEKLRKRTEEPDRDERLKK 249 Query: 324 QRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELGEDDDEQE 383 ++Q ++ + +R++E+ E RK+ E ++ + D E SR+ S D Sbjct: 250 EKQEREEREKEREREREERERKRRREEEEREKERARDRERRK-RSRSRSRHSSRTSD--- 305 Query: 384 DDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKS 443 +R ++S KR R +R R R D++ ++ D+S Sbjct: 306 -------------------------RRCSRSRDHKRSR-SRERRRSRSRDRRRSRSHDRS 339 Query: 444 QGAQARRGPRGASRDGGRGRGRGR 467 + R R SRD R + R R Sbjct: 340 E-----RKHRSRSRDRRRSKSRDR 358 >gi|166795262 AE binding protein 2 isoform a [Homo sapiens] Length = 503 Score = 40.4 bits (93), Expect = 0.004 Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 6/107 (5%) Query: 356 VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415 VGG + E PS ++ + GED+DE+EDD+ E + E E+ + L S Sbjct: 74 VGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEE----ESSAESLVGSS 129 Query: 416 GRKRKRWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGGRG 462 G G D +G + +GPRG+ GG G Sbjct: 130 GGSSSDETRSLSPGAASSSS--GDGDGKEGLEEPKGPRGSQGGGGGG 174 >gi|22758136 MAP7 domain containing 2 [Homo sapiens] Length = 732 Score = 40.4 bits (93), Expect = 0.004 Identities = 38/146 (26%), Positives = 62/146 (42%), Gaps = 10/146 (6%) Query: 234 GAGLSESEAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEG 293 G G S + + P+G T LP +A G +R Q R P+ +K E Sbjct: 4 GGGGSGTGSRPEGTARGTSLPGKIAEPGAVRTSQPNYR-----PQGMEGFLKSDERQRLA 58 Query: 294 KVMFHSFVSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKK 353 K Q ILE K+K+ RL+ ++Q ++ +Q QRE ++ ++E +K Sbjct: 59 KERREEREKCLAAREQQILE-KQKRARLQYEKQMEERWRKLEEQRQREDQKRAAVEEKRK 117 Query: 354 ARVGGSDEEASGIP----SRTASLEL 375 ++ +E + RT LEL Sbjct: 118 QKLREEEERLEAMMRRSLERTQQLEL 143 Score = 32.7 bits (73), Expect = 0.73 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 8/89 (8%) Query: 303 KTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQR---EAHRKKSLEGMKKARVGGS 359 + E+E Q LE +E L+ KA+ + + + RKQE+ + KK EG +K + G Sbjct: 422 RVEKEEQDRLEREE--LKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAG-- 477 Query: 360 DEEASGIPSRTASLELGEDDDEQEDDDIE 388 EEA L+ ++ ++QE IE Sbjct: 478 -EEAKRKAEEELLLKEKQEQEKQEKAMIE 505 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 40.0 bits (92), Expect = 0.005 Identities = 28/124 (22%), Positives = 61/124 (49%), Gaps = 3/124 (2%) Query: 299 SFVSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGG 358 S S+ EEE + E +E+++R + + + ++ + +++ E+ E +KK + KK V Sbjct: 2242 SLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQE 2301 Query: 359 SD---EEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415 + EE I S + L ++++E+E +E E ++ + +++R Sbjct: 2302 KEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLR 2361 Query: 416 GRKR 419 GR+R Sbjct: 2362 GRER 2365 Score = 34.7 bits (78), Expect = 0.19 Identities = 39/173 (22%), Positives = 81/173 (46%), Gaps = 26/173 (15%) Query: 294 KVMFHSFVSKTE------EELQAILEAKEKKLRLKAQRQAQQAQNVQRKQE---QREAHR 344 K F S V + E EE++++L+ EK+ L ++ + ++ + +R++E + E R Sbjct: 2210 KEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEER 2269 Query: 345 KKSLEGMKKARVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFP 404 K+ EG +K +V +EE + E +++ +++++ E + + E +E L Sbjct: 2270 KEEEEGEEK-QVEKEEEE-----KKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSD 2323 Query: 405 EAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASR 457 E +++ E+DR + L +K K ++ Q R+ RG R Sbjct: 2324 EEEEEESCS------LEEEVDREKEILKKEKQFKLQE-----QRRKSLRGRER 2365 >gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapiens] Length = 437 Score = 40.0 bits (92), Expect = 0.005 Identities = 38/158 (24%), Positives = 64/158 (40%), Gaps = 17/158 (10%) Query: 315 KEKKLRLKAQRQAQQAQNVQRKQEQREAH-RKKSLEGMKKARVGGSDEEASGIPSRTASL 373 KE++ R R ++ + K+E+R + R K + +K R S E A R L Sbjct: 250 KERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEEL 309 Query: 374 ELGEDDDEQEDDDIEYFCQAVGEAPSED-----LFPEAKQKRLAKSPGRKRKRWEMDRGR 428 G D + + G+AP +D L P+ K R R+R R Sbjct: 310 RGGGGDMAEPSE--------AGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSE 361 Query: 429 GRLCDQKFPKTKDKSQGAQARRGPRGASRDGGRGRGRG 466 +++ + +D+ + + +RG RG+ R RG G Sbjct: 362 R---ERRRDRDRDRDRDREHKRGERGSERGRDEARGGG 396 >gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 [Homo sapiens] Length = 2542 Score = 40.0 bits (92), Expect = 0.005 Identities = 25/73 (34%), Positives = 42/73 (57%), Gaps = 7/73 (9%) Query: 317 KKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELG 376 K+L L+ R+ + Q + K+E+R+ RKK E K+ + +E+ P + EL Sbjct: 1433 KELDLEKSREESRKQALAAKREKRKEKRKKKKEEQKRKQ----EEDEENKPKENS--ELP 1486 Query: 377 EDDDEQE-DDDIE 388 ED+DE+E D+D+E Sbjct: 1487 EDEDEEENDEDVE 1499 >gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens] Length = 2617 Score = 40.0 bits (92), Expect = 0.005 Identities = 25/73 (34%), Positives = 42/73 (57%), Gaps = 7/73 (9%) Query: 317 KKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELG 376 K+L L+ R+ + Q + K+E+R+ RKK E K+ + +E+ P + EL Sbjct: 1433 KELDLEKSREESRKQALAAKREKRKEKRKKKKEEQKRKQ----EEDEENKPKENS--ELP 1486 Query: 377 EDDDEQE-DDDIE 388 ED+DE+E D+D+E Sbjct: 1487 EDEDEEENDEDVE 1499 >gi|213385278 TNF receptor-associated factor 3 interacting protein 1 isoform 2 [Homo sapiens] Length = 625 Score = 39.3 bits (90), Expect = 0.008 Identities = 42/161 (26%), Positives = 71/161 (44%), Gaps = 11/161 (6%) Query: 313 EAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTAS 372 E E K R ++Q+ N ++E+ H K+ E A + +E S R Sbjct: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVH--KNTEDRGDAEI----KERSTSRDRKQK 185 Query: 373 LELGEDDDEQEDD-DIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRKRWEMDRGRGRL 431 EL ED +E D D E + G E E ++ + P +R++ +R R R Sbjct: 186 EELKEDRKPREKDKDKEKAKENGGNRHREG---ERERAKARARPDNERQKDRGNRERDRD 242 Query: 432 CDQKFPKTKDKSQGAQARRGPRGASRDGGRGRGRGRPGKRV 472 ++K +T+ KS+G + + R R+ R +G+ R +RV Sbjct: 243 SERK-KETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRV 282 >gi|20070262 TNF receptor-associated factor 3 interacting protein 1 isoform 1 [Homo sapiens] Length = 691 Score = 39.3 bits (90), Expect = 0.008 Identities = 42/161 (26%), Positives = 71/161 (44%), Gaps = 11/161 (6%) Query: 313 EAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTAS 372 E E K R ++Q+ N ++E+ H K+ E A + +E S R Sbjct: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVH--KNTEDRGDAEI----KERSTSRDRKQK 185 Query: 373 LELGEDDDEQEDD-DIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRKRWEMDRGRGRL 431 EL ED +E D D E + G E E ++ + P +R++ +R R R Sbjct: 186 EELKEDRKPREKDKDKEKAKENGGNRHREG---ERERAKARARPDNERQKDRGNRERDRD 242 Query: 432 CDQKFPKTKDKSQGAQARRGPRGASRDGGRGRGRGRPGKRV 472 ++K +T+ KS+G + + R R+ R +G+ R +RV Sbjct: 243 SERK-KETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRV 282 >gi|148806928 hypothetical protein LOC57482 [Homo sapiens] Length = 1233 Score = 39.3 bits (90), Expect = 0.008 Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 41/191 (21%) Query: 303 KTEEELQAILEAKEKKLRLKAQRQAQQAQNVQ--------RKQEQREAHRKKSLEGMKKA 354 + E E + LEA+E++ RL+AQ QA++ + ++ R+QE+ E + L+ ++ Sbjct: 305 RREREERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQEEE 364 Query: 355 RVGGSDE------EASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDL------ 402 G +E E G P G E+ED E + G+A ED Sbjct: 365 EAEGWEELEQQEAEVQGPPEALEETGEGRRGAEEEDLGEE---EEEGQAHLEDWRGQLSE 421 Query: 403 ----FPEAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRD 458 F E + + P +R+ E +C+++ P+ A+ RR +G S Sbjct: 422 LLNDFEERLEDQERLKPEGQREHSE----EPGICEEQNPE-------AERRREQQGRS-- 468 Query: 459 GGRGRGRGRPG 469 G +G RPG Sbjct: 469 -GDFQGADRPG 478 Score = 34.3 bits (77), Expect = 0.25 Identities = 42/193 (21%), Positives = 80/193 (41%), Gaps = 20/193 (10%) Query: 291 GEGKVMFHSFVSKT--EEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQR-------- 340 GE K +H EE + E ++L K +RQ +A +R +EQR Sbjct: 201 GEDKPTWHEEEPNPLDSEEERRRQEDYWRELEAKCKRQKAEAAEKRRLEEQRLQALERRL 260 Query: 341 --EAHRKKSLEGMKKARVGGSDEEASGIPSRTASLEL-GEDDDEQEDDDIEYFCQAVGEA 397 E R++ LE + + + E + + SLE G +D E+ + + +A E Sbjct: 261 WEENRRQELLEEEGEGQEPPLEAERAPREEQQRSLEAPGWEDAERREREERERLEAEEER 320 Query: 398 PSEDLFPEAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQGAQAR-------R 450 +A+++R + R +R + GR ++ + +++++G + + Sbjct: 321 RRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQEEEEAEGWEELEQQEAEVQ 380 Query: 451 GPRGASRDGGRGR 463 GP A + G GR Sbjct: 381 GPPEALEETGEGR 393 >gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] Length = 494 Score = 38.5 bits (88), Expect = 0.013 Identities = 32/156 (20%), Positives = 67/156 (42%), Gaps = 3/156 (1%) Query: 317 KKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELG 376 K K++ +++ + K R R +S + +K+R ++ S S S Sbjct: 212 KSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKK--EKSRSPSKEKSRSRSHSAGKSRSKS 269 Query: 377 EDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKF 436 +D E++ + + + +PS + R + + KR + RGR + + Sbjct: 270 KDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQ 329 Query: 437 PKTKDKSQ-GAQARRGPRGASRDGGRGRGRGRPGKR 471 +++ +S+ G+++R R S+D +GR R R R Sbjct: 330 SRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESR 365 Score = 33.9 bits (76), Expect = 0.33 Identities = 34/184 (18%), Positives = 74/184 (40%), Gaps = 12/184 (6%) Query: 292 EGKVMFHSFVSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSL-EG 350 E K+ + V K + + ++K K +++ Q ++ + +R R ++KSL + Sbjct: 274 EEKIQNNDNVGKPKSRSPSRHKSKSKS---RSRSQERRVEEEKRGSVSRGRSQEKSLRQS 330 Query: 351 MKKARVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKR 410 ++R G S S++ G +E ++ + SE ++ Sbjct: 331 RSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRS-----RSRSRSKSERSRKRGSKRD 385 Query: 411 LAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGGRG---RGRGR 467 +K+K+ + DR + R + K ++ ++ ++R RG S + G R R R Sbjct: 386 SKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSR 445 Query: 468 PGKR 471 + Sbjct: 446 SNSK 449 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.133 0.377 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,002,756 Number of Sequences: 37866 Number of extensions: 839839 Number of successful extensions: 8892 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 80 Number of HSP's successfully gapped in prelim test: 354 Number of HSP's that attempted gapping in prelim test: 7227 Number of HSP's gapped (non-prelim): 1423 length of query: 473 length of database: 18,247,518 effective HSP length: 106 effective length of query: 367 effective length of database: 14,233,722 effective search space: 5223775974 effective search space used: 5223775974 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.