Guide to the Human Genome
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Search of human proteins with 47174861

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|47174861 peter pan homolog [Homo sapiens]
         (473 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|47174861 peter pan homolog [Homo sapiens]                          938   0.0  
gi|99028871 PPAN-P2RY11 protein [Homo sapiens]                        845   0.0  
gi|153791630 bromodomain and WD repeat domain containing 3 [Homo...    43   5e-04
gi|7661952 squamous cell carcinoma antigen recognized by T cells...    43   7e-04
gi|157676331 hyaluronan binding protein 4 [Homo sapiens]               42   0.001
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]            42   0.002
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    41   0.002
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        41   0.003
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        41   0.003
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         41   0.003
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         41   0.003
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                         41   0.003
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         41   0.003
gi|41322912 plectin 1 isoform 2 [Homo sapiens]                         41   0.003
gi|47607492 plectin 1 isoform 1 [Homo sapiens]                         41   0.003
gi|10947135 ATP-binding cassette, sub-family F, member 1 isoform...    40   0.004
gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform...    40   0.004
gi|166795264 AE binding protein 2 isoform b [Homo sapiens]             40   0.004
gi|52426743 cisplatin resistance-associated overexpressed protei...    40   0.004
gi|19923485 cisplatin resistance-associated overexpressed protei...    40   0.004
gi|166795262 AE binding protein 2 isoform a [Homo sapiens]             40   0.004
gi|22758136 MAP7 domain containing 2 [Homo sapiens]                    40   0.004
gi|221219020 NYD-SP11 protein [Homo sapiens]                           40   0.005
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi...    40   0.005
gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 ...    40   0.005
gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens]                     40   0.005
gi|213385278 TNF receptor-associated factor 3 interacting protei...    39   0.008
gi|20070262 TNF receptor-associated factor 3 interacting protein...    39   0.008
gi|148806928 hypothetical protein LOC57482 [Homo sapiens]              39   0.008
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     39   0.013

>gi|47174861 peter pan homolog [Homo sapiens]
          Length = 473

 Score =  938 bits (2424), Expect = 0.0
 Identities = 473/473 (100%), Positives = 473/473 (100%)

Query: 1   MGQSGRSRHQKRARAQAQLRNLEAYAANPHSFVFTRGCTGRNIRQLSLDVRRVMEPLTAS 60
           MGQSGRSRHQKRARAQAQLRNLEAYAANPHSFVFTRGCTGRNIRQLSLDVRRVMEPLTAS
Sbjct: 1   MGQSGRSRHQKRARAQAQLRNLEAYAANPHSFVFTRGCTGRNIRQLSLDVRRVMEPLTAS 60

Query: 61  RLQVRKKNSLKDCVAVAGPLGVTHFLILSKTETNVYFKLMRLPGGPTLTFQVKKYSLVRD 120
           RLQVRKKNSLKDCVAVAGPLGVTHFLILSKTETNVYFKLMRLPGGPTLTFQVKKYSLVRD
Sbjct: 61  RLQVRKKNSLKDCVAVAGPLGVTHFLILSKTETNVYFKLMRLPGGPTLTFQVKKYSLVRD 120

Query: 121 VVSSLRRHRMHEQQFAHPPLLVLNSFGPHGMHVKLMATMFQNLFPSINVHKVNLNTIKRC 180
           VVSSLRRHRMHEQQFAHPPLLVLNSFGPHGMHVKLMATMFQNLFPSINVHKVNLNTIKRC
Sbjct: 121 VVSSLRRHRMHEQQFAHPPLLVLNSFGPHGMHVKLMATMFQNLFPSINVHKVNLNTIKRC 180

Query: 181 LLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGAGLSES 240
           LLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGAGLSES
Sbjct: 181 LLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGAGLSES 240

Query: 241 EAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSF 300
           EAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSF
Sbjct: 241 EAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSF 300

Query: 301 VSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSD 360
           VSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSD
Sbjct: 301 VSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSD 360

Query: 361 EEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRK 420
           EEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRK
Sbjct: 361 EEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRK 420

Query: 421 RWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGGRGRGRGRPGKRVA 473
           RWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGGRGRGRGRPGKRVA
Sbjct: 421 RWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGGRGRGRGRPGKRVA 473


>gi|99028871 PPAN-P2RY11 protein [Homo sapiens]
          Length = 794

 Score =  845 bits (2182), Expect = 0.0
 Identities = 433/448 (96%), Positives = 434/448 (96%), Gaps = 2/448 (0%)

Query: 1   MGQSGRSRHQKRARAQAQLRNLEAYAANPHSFVFTRGCTGRNIRQLSLDVRRVMEPLTAS 60
           MGQSGRSRHQKRARAQAQLRNLEAYAANPHSFVFTRGCTGRNIRQLSLDVRRVMEPLTAS
Sbjct: 1   MGQSGRSRHQKRARAQAQLRNLEAYAANPHSFVFTRGCTGRNIRQLSLDVRRVMEPLTAS 60

Query: 61  RLQVRKKNSLKDCVAVAGPLGVTHFLILSKTETNVYFKLMRLPGGPTLTFQVKKYSLVRD 120
           RLQVRKKNSLKDCVAVAGPLGVTHFLILSKTETNVYFKLMRLPGGPTLTFQVKKYSLVRD
Sbjct: 61  RLQVRKKNSLKDCVAVAGPLGVTHFLILSKTETNVYFKLMRLPGGPTLTFQVKKYSLVRD 120

Query: 121 VVSSLRRHRMHEQQFAHPPLLVLNSFGPHGMHVKLMATMFQNLFPSINVHKVNLNTIKRC 180
           VVSSLRRHRMHEQQFAHPPLLVLNSFGPHGMHVKLMATMFQNLFPSINVHKVNLNTIKRC
Sbjct: 121 VVSSLRRHRMHEQQFAHPPLLVLNSFGPHGMHVKLMATMFQNLFPSINVHKVNLNTIKRC 180

Query: 181 LLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGAGLSES 240
           LLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGAGLSES
Sbjct: 181 LLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGAGLSES 240

Query: 241 EAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSF 300
           EAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSF
Sbjct: 241 EAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSF 300

Query: 301 VSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSD 360
           VSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSD
Sbjct: 301 VSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSD 360

Query: 361 EEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRK 420
           EEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRK
Sbjct: 361 EEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRK 420

Query: 421 RWEMDRGRGRLCDQKF-PKTKDKSQGAQ 447
           RWEMDRG  + C   F     DK  G Q
Sbjct: 421 RWEMDRG-AKSCPANFLAAADDKLSGFQ 447


>gi|153791630 bromodomain and WD repeat domain containing 3 [Homo
            sapiens]
          Length = 1802

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 37/136 (27%), Positives = 55/136 (40%), Gaps = 13/136 (9%)

Query: 337  QEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGE 396
            +E++E   K  L   +   +G S    S   S + S      D +  D D +Y       
Sbjct: 1590 KEKKETKEKSHLSTSESGELGSSLSSESTCGSDSDSESTSRTDQDYVDGDHDY------- 1642

Query: 397  APSEDLFPEAKQKR-LAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQGAQAR-RGPRG 454
                  F + + KR L K  G  ++ W+     GR    ++ +     +G   R RG RG
Sbjct: 1643 ----SKFIQTRPKRKLRKQHGNGKRNWKTRGTGGRGRWGRWGRWSRGGRGRGGRGRGSRG 1698

Query: 455  ASRDGGRGRGRGRPGK 470
                G RGRGRGR G+
Sbjct: 1699 RGGGGTRGRGRGRGGR 1714


>gi|7661952 squamous cell carcinoma antigen recognized by T cells 3
           [Homo sapiens]
          Length = 963

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 39/170 (22%), Positives = 68/170 (40%), Gaps = 30/170 (17%)

Query: 264 RAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKTEEELQAI----LEAKEKKL 319
           +A   AV+ T   P    +++   E        +   V KTE  L  +    ++A EK+ 
Sbjct: 529 KALHRAVQCTSDYPEHVCEVLLTMERTEGSLEDWDIAVQKTETRLARVNEQRMKAAEKEA 588

Query: 320 RLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELGEDD 379
            L  Q + +  Q  + + E++   +KK + G +K      DE+           E G+D+
Sbjct: 589 ALVQQEEEKAEQRKRARAEKKALKKKKKIRGPEKRGADEDDEK-----------EWGDDE 637

Query: 380 DEQ---------------EDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKS 414
           +EQ               E  ++E      G+  + D+ P +KQK  A S
Sbjct: 638 EEQPSKRRRVENSIPAAGETQNVEVAAGPAGKCAAVDVEPPSKQKEKAAS 687


>gi|157676331 hyaluronan binding protein 4 [Homo sapiens]
          Length = 413

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 46/197 (23%), Positives = 75/197 (38%), Gaps = 22/197 (11%)

Query: 293 GKVMFHSFVSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRK------- 345
           G  M  SF          +L+ +     +  + + ++ Q +QRK+    A          
Sbjct: 13  GAAMQESFGCVVANRFHQLLDDESDPFDILREAERRRQQQLQRKRRDEAAAAAGAGPRGG 72

Query: 346 KSLEGMKKARVGG-----SDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSE 400
           +S  G    R G      S +E   +P+  A          Q         +   +  ++
Sbjct: 73  RSPAGASGHRAGAGGRRESQKERKSLPAPVAQRPDSPGGGLQAPGQKRTPRRGEQQGWND 132

Query: 401 DLFPEAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTK-----DKSQGAQARRGPRGA 455
              PE   +R  +   R+ + +E +R +     +KFP  K     D+ +  + R GPRG 
Sbjct: 133 SRGPEGMLERAERRSYREYRPYETER-QADFTAEKFPDEKPGDRFDRDRPLRGRGGPRG- 190

Query: 456 SRDGGRGRGRGRPGKRV 472
              G RGRGRG PG RV
Sbjct: 191 ---GMRGRGRGGPGNRV 204


>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 819

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 38/142 (26%), Positives = 60/142 (42%), Gaps = 17/142 (11%)

Query: 336 KQEQREAHRKKSLEGMKKARVGGSDEEAS--GIPSRTASLELGEDDDEQEDDDIEYFCQA 393
           K+ +R   +          R GG  ++A+  G+ SR      G+    Q+        + 
Sbjct: 323 KKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRG 382

Query: 394 VGEAPSEDLFPEAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQGAQA--RRG 451
            G+        EAK++      GRK+ RW+  R R     QK P  K +  G++   RRG
Sbjct: 383 GGDKKG---LREAKRR----GDGRKKPRWQNPRRRA----QKAPAAKPRGGGSKKPRRRG 431

Query: 452 PRGASRDGGRGRGRG--RPGKR 471
           P+ A   GG+ R  G  +P +R
Sbjct: 432 PKAAKSRGGKSRSGGGKKPRRR 453



 Score = 29.6 bits (65), Expect = 6.2
 Identities = 35/140 (25%), Positives = 52/140 (37%), Gaps = 13/140 (9%)

Query: 335 RKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAV 394
           R ++ R   +K +  G KK R       A+G  +R A  +        +           
Sbjct: 119 RGRKPRRRGQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQG-------- 170

Query: 395 GEAPSEDLFPEAKQKRLAKSP---GRKRKRWEMDRGRGRLCDQKFPKTKDKSQGAQARRG 451
           GE P +     AK  R  K P   G K +  E  +GR R    +F KT+   +    R  
Sbjct: 171 GEKPQKAAAAGAKS-RSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRRPK 229

Query: 452 PRGASRDGGRGRGRGRPGKR 471
           P        RG G+ +P K+
Sbjct: 230 PAAGGAKSRRGGGK-KPQKQ 248


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 38/156 (24%), Positives = 67/156 (42%), Gaps = 3/156 (1%)

Query: 315 KEKKLRLKAQRQAQQAQNVQRKQE-QREAHRKKSLEGMK-KARVGGSDEEASGIPSRTAS 372
           +E++   K QR+ ++ +  +RK+E QRE  R++     + + R    + E      R   
Sbjct: 279 RERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDRE 338

Query: 373 LELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRKRWEMDRGRGRLC 432
            E       Q + D E   Q   E   +      +++   +   R+R+  E DR R R  
Sbjct: 339 KERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQK 398

Query: 433 DQKFPKTKDK-SQGAQARRGPRGASRDGGRGRGRGR 467
           +++    KD+  Q    ++  R   R+  RGR RGR
Sbjct: 399 ERERQTEKDRDGQRETEKQREREKDRESERGRERGR 434



 Score = 36.2 bits (82), Expect = 0.066
 Identities = 42/174 (24%), Positives = 73/174 (41%), Gaps = 17/174 (9%)

Query: 305 EEELQAILEAKEKKLRLKAQRQAQQAQNVQR-------KQEQREAHRKKSLEGMKKARVG 357
           E E Q   E KE++ +   +RQ Q  +N Q+       +QE+RE  R++  E   + R  
Sbjct: 148 ERERQRDAE-KERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS 206

Query: 358 GSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGR 417
               E      R    E   + + +   D E   Q   E   E    +A+++R ++    
Sbjct: 207 ERGRE------RERERETETETERKRQTDRERDRQRKTERERE---KQAERERASERETE 257

Query: 418 KRKRWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGGRGRGRGRPGKR 471
           + K  E +R R R  D++  + + ++   + RR  R    +  R R R R  +R
Sbjct: 258 RDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER 311



 Score = 33.9 bits (76), Expect = 0.33
 Identities = 38/172 (22%), Positives = 64/172 (37%), Gaps = 25/172 (14%)

Query: 315 KEKKLRLKAQRQAQQAQNVQRKQEQ-REAHR-------KKSLEGMKKARVGGSDEEAS-- 364
           KE++ + +  R  Q+    QR++E+ RE+ R       ++  +G ++ R   +D +A   
Sbjct: 398 KERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQ 457

Query: 365 --------GIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPG 416
                     P RTA   + + D  +    I +         +   FP  +  + ++   
Sbjct: 458 RKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRV 517

Query: 417 RKRKRWEM-------DRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGGR 461
             R+RWE          G GR     F      SQ      GPR    DG R
Sbjct: 518 AGRRRWEPRLGEKRGQGGEGRRPSGGFGTENPLSQAPSVFPGPRYTPGDGKR 569



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 30/163 (18%), Positives = 70/163 (42%), Gaps = 12/163 (7%)

Query: 315 KEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLE 374
           KE++ R + ++  ++    + ++ +++ HRK+      + R    ++E      R    +
Sbjct: 60  KERERRREKRQTERETDRKRERRREKDRHRKRD---RHRERQRDREKERERQTDRERDRQ 116

Query: 375 LGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRKRWEMDRGRGRLCDQ 434
             ++ + Q++ + E   +  GE    D   + +++R  +    K +  + DR R R  ++
Sbjct: 117 REKERNRQKERERE--TEREGER-GRDRQTDGQRERERQRDAEKERERQTDRERQRQTER 173

Query: 435 KFPKTKDKSQGAQAR------RGPRGASRDGGRGRGRGRPGKR 471
              K +++ +  Q R      R     + D    RGR R  +R
Sbjct: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERER 216



 Score = 29.6 bits (65), Expect = 6.2
 Identities = 36/171 (21%), Positives = 67/171 (39%), Gaps = 20/171 (11%)

Query: 303 KTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEE 362
           +TE E +   +   ++ R +   + ++ Q  + +  +RE  R K  E  +          
Sbjct: 217 ETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERER---------- 266

Query: 363 ASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRKRW 422
                 R    +  + + E++ D      Q   E   E      +Q+   +   R RKR 
Sbjct: 267 -----DRDRDRDRRQKERERQTDRKR---QRRTERDRETERKRERQRERERERERNRKR- 317

Query: 423 EMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGGRGRGRGRPGKRVA 473
           E +R R R  +++    +D+ +  + +R  R    D  R R  GR G+R A
Sbjct: 318 ERERERERERERQRETERDREKERERKR-KRQTEMDRERNRQTGREGRRQA 367


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 11/147 (7%)

Query: 247  DHNITELPQAVAG--RGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKT 304
            DH+   L +A+A   R   + QQ A  L      M  Q ++ ++ + E + +  SF+S+ 
Sbjct: 2442 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM--QTVQQEQLLQETQALQQSFLSEK 2499

Query: 305  EEELQ--AILEAKEKKLRLKAQRQAQQAQNV----QRKQEQREAHRKKSLEGMKKARVGG 358
            +  LQ    +E ++ KL    Q +  +AQ +    QR+Q+Q E  R++ +  M++AR   
Sbjct: 2500 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-RR 2558

Query: 359  SDEEASGIPSRTASLELGEDDDEQEDD 385
              E   G+  +   L+  E    Q+++
Sbjct: 2559 QHEAEEGVRRKQEELQQLEQQRRQQEE 2585



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 25/170 (14%)

Query: 306  EELQAILEAKEKKLR---LKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS--- 359
            EEL+   E  E++LR   ++  RQ Q A    ++  + E   K++    K A++  S   
Sbjct: 1539 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1598

Query: 360  --------DEEASGIPSRTASLELGEDDDEQE--------DDDIEYFCQAVGEAPSEDL- 402
                     EEA     + A  E   ++ E+E        ++ +    QA   A  + L 
Sbjct: 1599 EHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLA 1658

Query: 403  -FPEAKQKRLAKSPGRKRKRWEMDRGRGR-LCDQKFPKTKDKSQGAQARR 450
                 KQK  A+   R+R + E    R R L +Q+  K +  ++G   +R
Sbjct: 1659 QAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1708



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 36/157 (22%), Positives = 75/157 (47%), Gaps = 15/157 (9%)

Query: 299  SFVSKTEEELQAILE--AKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKK-SLEGMKKAR 355
            SF  KT +  +++ E      +LR +A+R+AQQ    +R +E+ E   ++  L+  +  R
Sbjct: 1584 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1643

Query: 356  VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415
            +    EE +   S      L + + E++ ++ E   +  G+A  +      +Q+ LA+  
Sbjct: 1644 LRLQAEEVAQQKS------LAQAEAEKQKEEAEREARRRGKAEEQ----AVRQRELAEQE 1693

Query: 416  GRKRKRWEMDRGRGRL-CDQKFPKTK-DKSQGAQARR 450
              K+++      + RL  +Q+  + + +  QG Q R+
Sbjct: 1694 LEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1730



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 52/280 (18%), Positives = 110/280 (39%), Gaps = 16/280 (5%)

Query: 176  TIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGA 235
            T  R  L + +     LD     +K     A+R   ++ +E F    +++++S+L A   
Sbjct: 2189 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE 2248

Query: 236  GLSESEAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKV 295
              + +    D D N     Q  A +    A+++A RL+             +E + + + 
Sbjct: 2249 AENRALILRDKD-NTQRFLQEEAEKMKQVAEEAA-RLSVAAQEAARLRQLAEEDLAQQRA 2306

Query: 296  MFHSFVSKTEEELQAILEAKEKKLRLKAQRQA-----QQAQNVQRKQEQREAHRKKSLEG 350
            +    +   +E++QA+ EA   K   +  +Q      +QA+ +Q  +EQ      +  +G
Sbjct: 2307 LAEKML---KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2363

Query: 351  MKKA------RVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFP 404
             ++       R      EA  +  R A +   +   E++        + +GE        
Sbjct: 2364 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2423

Query: 405  EAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQ 444
              ++  L ++   +R++ + D  R R    +  + K+K Q
Sbjct: 2424 TQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQ 2463



 Score = 30.0 bits (66), Expect = 4.8
 Identities = 43/184 (23%), Positives = 72/184 (39%), Gaps = 43/184 (23%)

Query: 215  QEKFPNMSRLQDISELLATGAGLSES--EAEPDGDHNITELPQAVAGRGNMRAQQSAVRL 272
            Q++     RL ++   L     L+E+  +A+   +    EL Q        R Q+  VR 
Sbjct: 1353 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--------RMQEEVVRR 1404

Query: 273  TEIGPRMTLQLIKVQEGVGEGKVMFHSFVS--------------KTEEELQAI---LEAK 315
             E       Q   +QE + + +    + +               + EEE++ +   LEA 
Sbjct: 1405 EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEAT 1464

Query: 316  EKK----------LRLKAQ------RQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS 359
            E++          LR +A+      RQAQ+     R+Q Q E+ RK+  E    +RV   
Sbjct: 1465 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1524

Query: 360  DEEA 363
             E A
Sbjct: 1525 AEAA 1528


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 11/147 (7%)

Query: 247  DHNITELPQAVAG--RGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKT 304
            DH+   L +A+A   R   + QQ A  L      M  Q ++ ++ + E + +  SF+S+ 
Sbjct: 2446 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM--QTVQQEQLLQETQALQQSFLSEK 2503

Query: 305  EEELQ--AILEAKEKKLRLKAQRQAQQAQNV----QRKQEQREAHRKKSLEGMKKARVGG 358
            +  LQ    +E ++ KL    Q +  +AQ +    QR+Q+Q E  R++ +  M++AR   
Sbjct: 2504 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-RR 2562

Query: 359  SDEEASGIPSRTASLELGEDDDEQEDD 385
              E   G+  +   L+  E    Q+++
Sbjct: 2563 QHEAEEGVRRKQEELQQLEQQRRQQEE 2589



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 25/170 (14%)

Query: 306  EELQAILEAKEKKLR---LKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS--- 359
            EEL+   E  E++LR   ++  RQ Q A    ++  + E   K++    K A++  S   
Sbjct: 1543 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1602

Query: 360  --------DEEASGIPSRTASLELGEDDDEQE--------DDDIEYFCQAVGEAPSEDL- 402
                     EEA     + A  E   ++ E+E        ++ +    QA   A  + L 
Sbjct: 1603 EHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLA 1662

Query: 403  -FPEAKQKRLAKSPGRKRKRWEMDRGRGR-LCDQKFPKTKDKSQGAQARR 450
                 KQK  A+   R+R + E    R R L +Q+  K +  ++G   +R
Sbjct: 1663 QAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1712



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 36/157 (22%), Positives = 75/157 (47%), Gaps = 15/157 (9%)

Query: 299  SFVSKTEEELQAILE--AKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKK-SLEGMKKAR 355
            SF  KT +  +++ E      +LR +A+R+AQQ    +R +E+ E   ++  L+  +  R
Sbjct: 1588 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1647

Query: 356  VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415
            +    EE +   S      L + + E++ ++ E   +  G+A  +      +Q+ LA+  
Sbjct: 1648 LRLQAEEVAQQKS------LAQAEAEKQKEEAEREARRRGKAEEQ----AVRQRELAEQE 1697

Query: 416  GRKRKRWEMDRGRGRL-CDQKFPKTK-DKSQGAQARR 450
              K+++      + RL  +Q+  + + +  QG Q R+
Sbjct: 1698 LEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1734



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 52/280 (18%), Positives = 110/280 (39%), Gaps = 16/280 (5%)

Query: 176  TIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGA 235
            T  R  L + +     LD     +K     A+R   ++ +E F    +++++S+L A   
Sbjct: 2193 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE 2252

Query: 236  GLSESEAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKV 295
              + +    D D N     Q  A +    A+++A RL+             +E + + + 
Sbjct: 2253 AENRALILRDKD-NTQRFLQEEAEKMKQVAEEAA-RLSVAAQEAARLRQLAEEDLAQQRA 2310

Query: 296  MFHSFVSKTEEELQAILEAKEKKLRLKAQRQA-----QQAQNVQRKQEQREAHRKKSLEG 350
            +    +   +E++QA+ EA   K   +  +Q      +QA+ +Q  +EQ      +  +G
Sbjct: 2311 LAEKML---KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2367

Query: 351  MKKA------RVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFP 404
             ++       R      EA  +  R A +   +   E++        + +GE        
Sbjct: 2368 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2427

Query: 405  EAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQ 444
              ++  L ++   +R++ + D  R R    +  + K+K Q
Sbjct: 2428 TQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQ 2467



 Score = 30.0 bits (66), Expect = 4.8
 Identities = 43/184 (23%), Positives = 72/184 (39%), Gaps = 43/184 (23%)

Query: 215  QEKFPNMSRLQDISELLATGAGLSES--EAEPDGDHNITELPQAVAGRGNMRAQQSAVRL 272
            Q++     RL ++   L     L+E+  +A+   +    EL Q        R Q+  VR 
Sbjct: 1357 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--------RMQEEVVRR 1408

Query: 273  TEIGPRMTLQLIKVQEGVGEGKVMFHSFVS--------------KTEEELQAI---LEAK 315
             E       Q   +QE + + +    + +               + EEE++ +   LEA 
Sbjct: 1409 EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEAT 1468

Query: 316  EKK----------LRLKAQ------RQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS 359
            E++          LR +A+      RQAQ+     R+Q Q E+ RK+  E    +RV   
Sbjct: 1469 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1528

Query: 360  DEEA 363
             E A
Sbjct: 1529 AEAA 1532


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 11/147 (7%)

Query: 247  DHNITELPQAVAG--RGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKT 304
            DH+   L +A+A   R   + QQ A  L      M  Q ++ ++ + E + +  SF+S+ 
Sbjct: 2442 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM--QTVQQEQLLQETQALQQSFLSEK 2499

Query: 305  EEELQ--AILEAKEKKLRLKAQRQAQQAQNV----QRKQEQREAHRKKSLEGMKKARVGG 358
            +  LQ    +E ++ KL    Q +  +AQ +    QR+Q+Q E  R++ +  M++AR   
Sbjct: 2500 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-RR 2558

Query: 359  SDEEASGIPSRTASLELGEDDDEQEDD 385
              E   G+  +   L+  E    Q+++
Sbjct: 2559 QHEAEEGVRRKQEELQQLEQQRRQQEE 2585



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 25/170 (14%)

Query: 306  EELQAILEAKEKKLR---LKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS--- 359
            EEL+   E  E++LR   ++  RQ Q A    ++  + E   K++    K A++  S   
Sbjct: 1539 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1598

Query: 360  --------DEEASGIPSRTASLELGEDDDEQE--------DDDIEYFCQAVGEAPSEDL- 402
                     EEA     + A  E   ++ E+E        ++ +    QA   A  + L 
Sbjct: 1599 EHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLA 1658

Query: 403  -FPEAKQKRLAKSPGRKRKRWEMDRGRGR-LCDQKFPKTKDKSQGAQARR 450
                 KQK  A+   R+R + E    R R L +Q+  K +  ++G   +R
Sbjct: 1659 QAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1708



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 36/157 (22%), Positives = 75/157 (47%), Gaps = 15/157 (9%)

Query: 299  SFVSKTEEELQAILE--AKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKK-SLEGMKKAR 355
            SF  KT +  +++ E      +LR +A+R+AQQ    +R +E+ E   ++  L+  +  R
Sbjct: 1584 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1643

Query: 356  VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415
            +    EE +   S      L + + E++ ++ E   +  G+A  +      +Q+ LA+  
Sbjct: 1644 LRLQAEEVAQQKS------LAQAEAEKQKEEAEREARRRGKAEEQ----AVRQRELAEQE 1693

Query: 416  GRKRKRWEMDRGRGRL-CDQKFPKTK-DKSQGAQARR 450
              K+++      + RL  +Q+  + + +  QG Q R+
Sbjct: 1694 LEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1730



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 52/280 (18%), Positives = 110/280 (39%), Gaps = 16/280 (5%)

Query: 176  TIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGA 235
            T  R  L + +     LD     +K     A+R   ++ +E F    +++++S+L A   
Sbjct: 2189 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE 2248

Query: 236  GLSESEAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKV 295
              + +    D D N     Q  A +    A+++A RL+             +E + + + 
Sbjct: 2249 AENRALILRDKD-NTQRFLQEEAEKMKQVAEEAA-RLSVAAQEAARLRQLAEEDLAQQRA 2306

Query: 296  MFHSFVSKTEEELQAILEAKEKKLRLKAQRQA-----QQAQNVQRKQEQREAHRKKSLEG 350
            +    +   +E++QA+ EA   K   +  +Q      +QA+ +Q  +EQ      +  +G
Sbjct: 2307 LAEKML---KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2363

Query: 351  MKKA------RVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFP 404
             ++       R      EA  +  R A +   +   E++        + +GE        
Sbjct: 2364 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2423

Query: 405  EAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQ 444
              ++  L ++   +R++ + D  R R    +  + K+K Q
Sbjct: 2424 TQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQ 2463



 Score = 30.0 bits (66), Expect = 4.8
 Identities = 43/184 (23%), Positives = 72/184 (39%), Gaps = 43/184 (23%)

Query: 215  QEKFPNMSRLQDISELLATGAGLSES--EAEPDGDHNITELPQAVAGRGNMRAQQSAVRL 272
            Q++     RL ++   L     L+E+  +A+   +    EL Q        R Q+  VR 
Sbjct: 1353 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--------RMQEEVVRR 1404

Query: 273  TEIGPRMTLQLIKVQEGVGEGKVMFHSFVS--------------KTEEELQAI---LEAK 315
             E       Q   +QE + + +    + +               + EEE++ +   LEA 
Sbjct: 1405 EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEAT 1464

Query: 316  EKK----------LRLKAQ------RQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS 359
            E++          LR +A+      RQAQ+     R+Q Q E+ RK+  E    +RV   
Sbjct: 1465 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1524

Query: 360  DEEA 363
             E A
Sbjct: 1525 AEAA 1528


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 11/147 (7%)

Query: 247  DHNITELPQAVAG--RGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKT 304
            DH+   L +A+A   R   + QQ A  L      M  Q ++ ++ + E + +  SF+S+ 
Sbjct: 2410 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM--QTVQQEQLLQETQALQQSFLSEK 2467

Query: 305  EEELQ--AILEAKEKKLRLKAQRQAQQAQNV----QRKQEQREAHRKKSLEGMKKARVGG 358
            +  LQ    +E ++ KL    Q +  +AQ +    QR+Q+Q E  R++ +  M++AR   
Sbjct: 2468 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-RR 2526

Query: 359  SDEEASGIPSRTASLELGEDDDEQEDD 385
              E   G+  +   L+  E    Q+++
Sbjct: 2527 QHEAEEGVRRKQEELQQLEQQRRQQEE 2553



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 25/170 (14%)

Query: 306  EELQAILEAKEKKLR---LKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS--- 359
            EEL+   E  E++LR   ++  RQ Q A    ++  + E   K++    K A++  S   
Sbjct: 1507 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1566

Query: 360  --------DEEASGIPSRTASLELGEDDDEQE--------DDDIEYFCQAVGEAPSEDL- 402
                     EEA     + A  E   ++ E+E        ++ +    QA   A  + L 
Sbjct: 1567 EHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLA 1626

Query: 403  -FPEAKQKRLAKSPGRKRKRWEMDRGRGR-LCDQKFPKTKDKSQGAQARR 450
                 KQK  A+   R+R + E    R R L +Q+  K +  ++G   +R
Sbjct: 1627 QAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1676



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 36/157 (22%), Positives = 75/157 (47%), Gaps = 15/157 (9%)

Query: 299  SFVSKTEEELQAILE--AKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKK-SLEGMKKAR 355
            SF  KT +  +++ E      +LR +A+R+AQQ    +R +E+ E   ++  L+  +  R
Sbjct: 1552 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1611

Query: 356  VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415
            +    EE +   S      L + + E++ ++ E   +  G+A  +      +Q+ LA+  
Sbjct: 1612 LRLQAEEVAQQKS------LAQAEAEKQKEEAEREARRRGKAEEQ----AVRQRELAEQE 1661

Query: 416  GRKRKRWEMDRGRGRL-CDQKFPKTK-DKSQGAQARR 450
              K+++      + RL  +Q+  + + +  QG Q R+
Sbjct: 1662 LEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1698



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 52/280 (18%), Positives = 110/280 (39%), Gaps = 16/280 (5%)

Query: 176  TIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGA 235
            T  R  L + +     LD     +K     A+R   ++ +E F    +++++S+L A   
Sbjct: 2157 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE 2216

Query: 236  GLSESEAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKV 295
              + +    D D N     Q  A +    A+++A RL+             +E + + + 
Sbjct: 2217 AENRALILRDKD-NTQRFLQEEAEKMKQVAEEAA-RLSVAAQEAARLRQLAEEDLAQQRA 2274

Query: 296  MFHSFVSKTEEELQAILEAKEKKLRLKAQRQA-----QQAQNVQRKQEQREAHRKKSLEG 350
            +    +   +E++QA+ EA   K   +  +Q      +QA+ +Q  +EQ      +  +G
Sbjct: 2275 LAEKML---KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2331

Query: 351  MKKA------RVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFP 404
             ++       R      EA  +  R A +   +   E++        + +GE        
Sbjct: 2332 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2391

Query: 405  EAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQ 444
              ++  L ++   +R++ + D  R R    +  + K+K Q
Sbjct: 2392 TQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQ 2431



 Score = 30.0 bits (66), Expect = 4.8
 Identities = 43/184 (23%), Positives = 72/184 (39%), Gaps = 43/184 (23%)

Query: 215  QEKFPNMSRLQDISELLATGAGLSES--EAEPDGDHNITELPQAVAGRGNMRAQQSAVRL 272
            Q++     RL ++   L     L+E+  +A+   +    EL Q        R Q+  VR 
Sbjct: 1321 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--------RMQEEVVRR 1372

Query: 273  TEIGPRMTLQLIKVQEGVGEGKVMFHSFVS--------------KTEEELQAI---LEAK 315
             E       Q   +QE + + +    + +               + EEE++ +   LEA 
Sbjct: 1373 EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEAT 1432

Query: 316  EKK----------LRLKAQ------RQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS 359
            E++          LR +A+      RQAQ+     R+Q Q E+ RK+  E    +RV   
Sbjct: 1433 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1492

Query: 360  DEEA 363
             E A
Sbjct: 1493 AEAA 1496


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 11/147 (7%)

Query: 247  DHNITELPQAVAG--RGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKT 304
            DH+   L +A+A   R   + QQ A  L      M  Q ++ ++ + E + +  SF+S+ 
Sbjct: 2579 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM--QTVQQEQLLQETQALQQSFLSEK 2636

Query: 305  EEELQ--AILEAKEKKLRLKAQRQAQQAQNV----QRKQEQREAHRKKSLEGMKKARVGG 358
            +  LQ    +E ++ KL    Q +  +AQ +    QR+Q+Q E  R++ +  M++AR   
Sbjct: 2637 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-RR 2695

Query: 359  SDEEASGIPSRTASLELGEDDDEQEDD 385
              E   G+  +   L+  E    Q+++
Sbjct: 2696 QHEAEEGVRRKQEELQQLEQQRRQQEE 2722



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 25/170 (14%)

Query: 306  EELQAILEAKEKKLR---LKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS--- 359
            EEL+   E  E++LR   ++  RQ Q A    ++  + E   K++    K A++  S   
Sbjct: 1676 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1735

Query: 360  --------DEEASGIPSRTASLELGEDDDEQE--------DDDIEYFCQAVGEAPSEDL- 402
                     EEA     + A  E   ++ E+E        ++ +    QA   A  + L 
Sbjct: 1736 EHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLA 1795

Query: 403  -FPEAKQKRLAKSPGRKRKRWEMDRGRGR-LCDQKFPKTKDKSQGAQARR 450
                 KQK  A+   R+R + E    R R L +Q+  K +  ++G   +R
Sbjct: 1796 QAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1845



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 36/157 (22%), Positives = 75/157 (47%), Gaps = 15/157 (9%)

Query: 299  SFVSKTEEELQAILE--AKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKK-SLEGMKKAR 355
            SF  KT +  +++ E      +LR +A+R+AQQ    +R +E+ E   ++  L+  +  R
Sbjct: 1721 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1780

Query: 356  VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415
            +    EE +   S      L + + E++ ++ E   +  G+A  +      +Q+ LA+  
Sbjct: 1781 LRLQAEEVAQQKS------LAQAEAEKQKEEAEREARRRGKAEEQ----AVRQRELAEQE 1830

Query: 416  GRKRKRWEMDRGRGRL-CDQKFPKTK-DKSQGAQARR 450
              K+++      + RL  +Q+  + + +  QG Q R+
Sbjct: 1831 LEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1867



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 52/280 (18%), Positives = 110/280 (39%), Gaps = 16/280 (5%)

Query: 176  TIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGA 235
            T  R  L + +     LD     +K     A+R   ++ +E F    +++++S+L A   
Sbjct: 2326 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE 2385

Query: 236  GLSESEAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKV 295
              + +    D D N     Q  A +    A+++A RL+             +E + + + 
Sbjct: 2386 AENRALILRDKD-NTQRFLQEEAEKMKQVAEEAA-RLSVAAQEAARLRQLAEEDLAQQRA 2443

Query: 296  MFHSFVSKTEEELQAILEAKEKKLRLKAQRQA-----QQAQNVQRKQEQREAHRKKSLEG 350
            +    +   +E++QA+ EA   K   +  +Q      +QA+ +Q  +EQ      +  +G
Sbjct: 2444 LAEKML---KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2500

Query: 351  MKKA------RVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFP 404
             ++       R      EA  +  R A +   +   E++        + +GE        
Sbjct: 2501 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2560

Query: 405  EAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQ 444
              ++  L ++   +R++ + D  R R    +  + K+K Q
Sbjct: 2561 TQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQ 2600



 Score = 30.0 bits (66), Expect = 4.8
 Identities = 43/184 (23%), Positives = 72/184 (39%), Gaps = 43/184 (23%)

Query: 215  QEKFPNMSRLQDISELLATGAGLSES--EAEPDGDHNITELPQAVAGRGNMRAQQSAVRL 272
            Q++     RL ++   L     L+E+  +A+   +    EL Q        R Q+  VR 
Sbjct: 1490 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--------RMQEEVVRR 1541

Query: 273  TEIGPRMTLQLIKVQEGVGEGKVMFHSFVS--------------KTEEELQAI---LEAK 315
             E       Q   +QE + + +    + +               + EEE++ +   LEA 
Sbjct: 1542 EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEAT 1601

Query: 316  EKK----------LRLKAQ------RQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS 359
            E++          LR +A+      RQAQ+     R+Q Q E+ RK+  E    +RV   
Sbjct: 1602 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1661

Query: 360  DEEA 363
             E A
Sbjct: 1662 AEAA 1665


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 11/147 (7%)

Query: 247  DHNITELPQAVAG--RGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKT 304
            DH+   L +A+A   R   + QQ A  L      M  Q ++ ++ + E + +  SF+S+ 
Sbjct: 2420 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM--QTVQQEQLLQETQALQQSFLSEK 2477

Query: 305  EEELQ--AILEAKEKKLRLKAQRQAQQAQNV----QRKQEQREAHRKKSLEGMKKARVGG 358
            +  LQ    +E ++ KL    Q +  +AQ +    QR+Q+Q E  R++ +  M++AR   
Sbjct: 2478 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-RR 2536

Query: 359  SDEEASGIPSRTASLELGEDDDEQEDD 385
              E   G+  +   L+  E    Q+++
Sbjct: 2537 QHEAEEGVRRKQEELQQLEQQRRQQEE 2563



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 25/170 (14%)

Query: 306  EELQAILEAKEKKLR---LKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS--- 359
            EEL+   E  E++LR   ++  RQ Q A    ++  + E   K++    K A++  S   
Sbjct: 1517 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1576

Query: 360  --------DEEASGIPSRTASLELGEDDDEQE--------DDDIEYFCQAVGEAPSEDL- 402
                     EEA     + A  E   ++ E+E        ++ +    QA   A  + L 
Sbjct: 1577 EHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLA 1636

Query: 403  -FPEAKQKRLAKSPGRKRKRWEMDRGRGR-LCDQKFPKTKDKSQGAQARR 450
                 KQK  A+   R+R + E    R R L +Q+  K +  ++G   +R
Sbjct: 1637 QAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1686



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 36/157 (22%), Positives = 75/157 (47%), Gaps = 15/157 (9%)

Query: 299  SFVSKTEEELQAILE--AKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKK-SLEGMKKAR 355
            SF  KT +  +++ E      +LR +A+R+AQQ    +R +E+ E   ++  L+  +  R
Sbjct: 1562 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1621

Query: 356  VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415
            +    EE +   S      L + + E++ ++ E   +  G+A  +      +Q+ LA+  
Sbjct: 1622 LRLQAEEVAQQKS------LAQAEAEKQKEEAEREARRRGKAEEQ----AVRQRELAEQE 1671

Query: 416  GRKRKRWEMDRGRGRL-CDQKFPKTK-DKSQGAQARR 450
              K+++      + RL  +Q+  + + +  QG Q R+
Sbjct: 1672 LEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1708



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 52/280 (18%), Positives = 110/280 (39%), Gaps = 16/280 (5%)

Query: 176  TIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGA 235
            T  R  L + +     LD     +K     A+R   ++ +E F    +++++S+L A   
Sbjct: 2167 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE 2226

Query: 236  GLSESEAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKV 295
              + +    D D N     Q  A +    A+++A RL+             +E + + + 
Sbjct: 2227 AENRALILRDKD-NTQRFLQEEAEKMKQVAEEAA-RLSVAAQEAARLRQLAEEDLAQQRA 2284

Query: 296  MFHSFVSKTEEELQAILEAKEKKLRLKAQRQA-----QQAQNVQRKQEQREAHRKKSLEG 350
            +    +   +E++QA+ EA   K   +  +Q      +QA+ +Q  +EQ      +  +G
Sbjct: 2285 LAEKML---KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2341

Query: 351  MKKA------RVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFP 404
             ++       R      EA  +  R A +   +   E++        + +GE        
Sbjct: 2342 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2401

Query: 405  EAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQ 444
              ++  L ++   +R++ + D  R R    +  + K+K Q
Sbjct: 2402 TQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQ 2441



 Score = 30.0 bits (66), Expect = 4.8
 Identities = 43/184 (23%), Positives = 72/184 (39%), Gaps = 43/184 (23%)

Query: 215  QEKFPNMSRLQDISELLATGAGLSES--EAEPDGDHNITELPQAVAGRGNMRAQQSAVRL 272
            Q++     RL ++   L     L+E+  +A+   +    EL Q        R Q+  VR 
Sbjct: 1331 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--------RMQEEVVRR 1382

Query: 273  TEIGPRMTLQLIKVQEGVGEGKVMFHSFVS--------------KTEEELQAI---LEAK 315
             E       Q   +QE + + +    + +               + EEE++ +   LEA 
Sbjct: 1383 EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEAT 1442

Query: 316  EKK----------LRLKAQ------RQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS 359
            E++          LR +A+      RQAQ+     R+Q Q E+ RK+  E    +RV   
Sbjct: 1443 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1502

Query: 360  DEEA 363
             E A
Sbjct: 1503 AEAA 1506


>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
          Length = 4533

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 11/147 (7%)

Query: 247  DHNITELPQAVAG--RGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKT 304
            DH+   L +A+A   R   + QQ A  L      M  Q ++ ++ + E + +  SF+S+ 
Sbjct: 2428 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM--QTVQQEQLLQETQALQQSFLSEK 2485

Query: 305  EEELQ--AILEAKEKKLRLKAQRQAQQAQNV----QRKQEQREAHRKKSLEGMKKARVGG 358
            +  LQ    +E ++ KL    Q +  +AQ +    QR+Q+Q E  R++ +  M++AR   
Sbjct: 2486 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-RR 2544

Query: 359  SDEEASGIPSRTASLELGEDDDEQEDD 385
              E   G+  +   L+  E    Q+++
Sbjct: 2545 QHEAEEGVRRKQEELQQLEQQRRQQEE 2571



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 25/170 (14%)

Query: 306  EELQAILEAKEKKLR---LKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS--- 359
            EEL+   E  E++LR   ++  RQ Q A    ++  + E   K++    K A++  S   
Sbjct: 1525 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1584

Query: 360  --------DEEASGIPSRTASLELGEDDDEQE--------DDDIEYFCQAVGEAPSEDL- 402
                     EEA     + A  E   ++ E+E        ++ +    QA   A  + L 
Sbjct: 1585 EHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLA 1644

Query: 403  -FPEAKQKRLAKSPGRKRKRWEMDRGRGR-LCDQKFPKTKDKSQGAQARR 450
                 KQK  A+   R+R + E    R R L +Q+  K +  ++G   +R
Sbjct: 1645 QAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1694



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 36/157 (22%), Positives = 75/157 (47%), Gaps = 15/157 (9%)

Query: 299  SFVSKTEEELQAILE--AKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKK-SLEGMKKAR 355
            SF  KT +  +++ E      +LR +A+R+AQQ    +R +E+ E   ++  L+  +  R
Sbjct: 1570 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1629

Query: 356  VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415
            +    EE +   S      L + + E++ ++ E   +  G+A  +      +Q+ LA+  
Sbjct: 1630 LRLQAEEVAQQKS------LAQAEAEKQKEEAEREARRRGKAEEQ----AVRQRELAEQE 1679

Query: 416  GRKRKRWEMDRGRGRL-CDQKFPKTK-DKSQGAQARR 450
              K+++      + RL  +Q+  + + +  QG Q R+
Sbjct: 1680 LEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1716



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 52/280 (18%), Positives = 110/280 (39%), Gaps = 16/280 (5%)

Query: 176  TIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGA 235
            T  R  L + +     LD     +K     A+R   ++ +E F    +++++S+L A   
Sbjct: 2175 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE 2234

Query: 236  GLSESEAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKV 295
              + +    D D N     Q  A +    A+++A RL+             +E + + + 
Sbjct: 2235 AENRALILRDKD-NTQRFLQEEAEKMKQVAEEAA-RLSVAAQEAARLRQLAEEDLAQQRA 2292

Query: 296  MFHSFVSKTEEELQAILEAKEKKLRLKAQRQA-----QQAQNVQRKQEQREAHRKKSLEG 350
            +    +   +E++QA+ EA   K   +  +Q      +QA+ +Q  +EQ      +  +G
Sbjct: 2293 LAEKML---KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2349

Query: 351  MKKA------RVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFP 404
             ++       R      EA  +  R A +   +   E++        + +GE        
Sbjct: 2350 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2409

Query: 405  EAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQ 444
              ++  L ++   +R++ + D  R R    +  + K+K Q
Sbjct: 2410 TQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQ 2449



 Score = 30.0 bits (66), Expect = 4.8
 Identities = 43/184 (23%), Positives = 72/184 (39%), Gaps = 43/184 (23%)

Query: 215  QEKFPNMSRLQDISELLATGAGLSES--EAEPDGDHNITELPQAVAGRGNMRAQQSAVRL 272
            Q++     RL ++   L     L+E+  +A+   +    EL Q        R Q+  VR 
Sbjct: 1339 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--------RMQEEVVRR 1390

Query: 273  TEIGPRMTLQLIKVQEGVGEGKVMFHSFVS--------------KTEEELQAI---LEAK 315
             E       Q   +QE + + +    + +               + EEE++ +   LEA 
Sbjct: 1391 EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEAT 1450

Query: 316  EKK----------LRLKAQ------RQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS 359
            E++          LR +A+      RQAQ+     R+Q Q E+ RK+  E    +RV   
Sbjct: 1451 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1510

Query: 360  DEEA 363
             E A
Sbjct: 1511 AEAA 1514


>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
          Length = 4574

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 11/147 (7%)

Query: 247  DHNITELPQAVAG--RGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKT 304
            DH+   L +A+A   R   + QQ A  L      M  Q ++ ++ + E + +  SF+S+ 
Sbjct: 2469 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM--QTVQQEQLLQETQALQQSFLSEK 2526

Query: 305  EEELQ--AILEAKEKKLRLKAQRQAQQAQNV----QRKQEQREAHRKKSLEGMKKARVGG 358
            +  LQ    +E ++ KL    Q +  +AQ +    QR+Q+Q E  R++ +  M++AR   
Sbjct: 2527 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-RR 2585

Query: 359  SDEEASGIPSRTASLELGEDDDEQEDD 385
              E   G+  +   L+  E    Q+++
Sbjct: 2586 QHEAEEGVRRKQEELQQLEQQRRQQEE 2612



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 25/170 (14%)

Query: 306  EELQAILEAKEKKLR---LKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS--- 359
            EEL+   E  E++LR   ++  RQ Q A    ++  + E   K++    K A++  S   
Sbjct: 1566 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1625

Query: 360  --------DEEASGIPSRTASLELGEDDDEQE--------DDDIEYFCQAVGEAPSEDL- 402
                     EEA     + A  E   ++ E+E        ++ +    QA   A  + L 
Sbjct: 1626 EHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLA 1685

Query: 403  -FPEAKQKRLAKSPGRKRKRWEMDRGRGR-LCDQKFPKTKDKSQGAQARR 450
                 KQK  A+   R+R + E    R R L +Q+  K +  ++G   +R
Sbjct: 1686 QAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1735



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 36/157 (22%), Positives = 75/157 (47%), Gaps = 15/157 (9%)

Query: 299  SFVSKTEEELQAILE--AKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKK-SLEGMKKAR 355
            SF  KT +  +++ E      +LR +A+R+AQQ    +R +E+ E   ++  L+  +  R
Sbjct: 1611 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1670

Query: 356  VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415
            +    EE +   S      L + + E++ ++ E   +  G+A  +      +Q+ LA+  
Sbjct: 1671 LRLQAEEVAQQKS------LAQAEAEKQKEEAEREARRRGKAEEQ----AVRQRELAEQE 1720

Query: 416  GRKRKRWEMDRGRGRL-CDQKFPKTK-DKSQGAQARR 450
              K+++      + RL  +Q+  + + +  QG Q R+
Sbjct: 1721 LEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1757



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 52/280 (18%), Positives = 110/280 (39%), Gaps = 16/280 (5%)

Query: 176  TIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGA 235
            T  R  L + +     LD     +K     A+R   ++ +E F    +++++S+L A   
Sbjct: 2216 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE 2275

Query: 236  GLSESEAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKV 295
              + +    D D N     Q  A +    A+++A RL+             +E + + + 
Sbjct: 2276 AENRALILRDKD-NTQRFLQEEAEKMKQVAEEAA-RLSVAAQEAARLRQLAEEDLAQQRA 2333

Query: 296  MFHSFVSKTEEELQAILEAKEKKLRLKAQRQA-----QQAQNVQRKQEQREAHRKKSLEG 350
            +    +   +E++QA+ EA   K   +  +Q      +QA+ +Q  +EQ      +  +G
Sbjct: 2334 LAEKML---KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2390

Query: 351  MKKA------RVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFP 404
             ++       R      EA  +  R A +   +   E++        + +GE        
Sbjct: 2391 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2450

Query: 405  EAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQ 444
              ++  L ++   +R++ + D  R R    +  + K+K Q
Sbjct: 2451 TQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQ 2490



 Score = 30.0 bits (66), Expect = 4.8
 Identities = 43/184 (23%), Positives = 72/184 (39%), Gaps = 43/184 (23%)

Query: 215  QEKFPNMSRLQDISELLATGAGLSES--EAEPDGDHNITELPQAVAGRGNMRAQQSAVRL 272
            Q++     RL ++   L     L+E+  +A+   +    EL Q        R Q+  VR 
Sbjct: 1380 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--------RMQEEVVRR 1431

Query: 273  TEIGPRMTLQLIKVQEGVGEGKVMFHSFVS--------------KTEEELQAI---LEAK 315
             E       Q   +QE + + +    + +               + EEE++ +   LEA 
Sbjct: 1432 EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEAT 1491

Query: 316  EKK----------LRLKAQ------RQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGS 359
            E++          LR +A+      RQAQ+     R+Q Q E+ RK+  E    +RV   
Sbjct: 1492 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1551

Query: 360  DEEA 363
             E A
Sbjct: 1552 AEAA 1555


>gi|10947135 ATP-binding cassette, sub-family F, member 1 isoform b
           [Homo sapiens]
          Length = 807

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 44/169 (26%), Positives = 77/169 (45%), Gaps = 34/169 (20%)

Query: 286 VQEGVGEGKVMFHSFVSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRK 345
           V++G  + K+    F     E+ QA  E  EK L+ K Q+Q QQ Q  ++K++ R+  RK
Sbjct: 28  VKKGKKDKKIKKTFFEELAVEDKQAGEE--EKVLKEKEQQQQQQQQQQKKKRDTRKGRRK 85

Query: 346 KS----------LEGMKKARVGGSDEE--------ASGIPSRTASL--ELGEDDDEQEDD 385
           K           +E +KK  V  SDEE          G  ++  ++   L +D  E+E++
Sbjct: 86  KDVDDDGEEKELMERLKKLSVPTSDEEDEVPAPKPRGGKKTKGGNVFAALIQDQSEEEEE 145

Query: 386 DIEYFCQAVGEAPSEDLFPEAKQKRLAKS----PGRKRKRWEMDRGRGR 430
           + ++        P +   PE  +   A S    P  K K+ + ++ +G+
Sbjct: 146 EEKH--------PPKPAKPEKNRINKAVSEEQQPALKGKKGKEEKSKGK 186


>gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform a
           [Homo sapiens]
          Length = 845

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 44/169 (26%), Positives = 77/169 (45%), Gaps = 34/169 (20%)

Query: 286 VQEGVGEGKVMFHSFVSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRK 345
           V++G  + K+    F     E+ QA  E  EK L+ K Q+Q QQ Q  ++K++ R+  RK
Sbjct: 28  VKKGKKDKKIKKTFFEELAVEDKQAGEE--EKVLKEKEQQQQQQQQQQKKKRDTRKGRRK 85

Query: 346 KS----------LEGMKKARVGGSDEE--------ASGIPSRTASL--ELGEDDDEQEDD 385
           K           +E +KK  V  SDEE          G  ++  ++   L +D  E+E++
Sbjct: 86  KDVDDDGEEKELMERLKKLSVPTSDEEDEVPAPKPRGGKKTKGGNVFAALIQDQSEEEEE 145

Query: 386 DIEYFCQAVGEAPSEDLFPEAKQKRLAKS----PGRKRKRWEMDRGRGR 430
           + ++        P +   PE  +   A S    P  K K+ + ++ +G+
Sbjct: 146 EEKH--------PPKPAKPEKNRINKAVSEEQQPALKGKKGKEEKSKGK 186


>gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
          Length = 517

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 6/107 (5%)

Query: 356 VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415
           VGG + E    PS  ++ + GED+DE+EDD+ E    +      E    E+  + L  S 
Sbjct: 74  VGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEE----ESSAESLVGSS 129

Query: 416 GRKRKRWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGGRG 462
           G            G           D  +G +  +GPRG+   GG G
Sbjct: 130 GGSSSDETRSLSPGAASSSS--GDGDGKEGLEEPKGPRGSQGGGGGG 174


>gi|52426743 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 59/264 (22%), Positives = 109/264 (41%), Gaps = 57/264 (21%)

Query: 204 VGASRGMKKLLQEKFPNMSRLQDISELLATGAGLSESEAEPDGDHNITELPQAVAGRGNM 263
           V  ++GM KL+++       L++  ELL +     ES A  +    + E+  A    G+ 
Sbjct: 152 VEEAQGMMKLVEQ-------LKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDA 204

Query: 264 RAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKTEEELQAILEAKEKKLRLKA 323
           ++            R+   L+  Q  +G  K+   + V + +E+L+   E  ++  RLK 
Sbjct: 205 QS------------RVDDHLMGKQH-MGYAKIK--ATVEELKEKLRKRTEEPDRDERLKK 249

Query: 324 QRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELGEDDDEQE 383
           ++Q ++ +  +R++E+ E  RK+  E  ++ +    D E     SR+ S       D   
Sbjct: 250 EKQEREEREKEREREREERERKRRREEEEREKERARDRERRK-RSRSRSRHSSRTSD--- 305

Query: 384 DDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKS 443
                                    +R ++S   KR R   +R R R  D++  ++ D+S
Sbjct: 306 -------------------------RRCSRSRDHKRSR-SRERRRSRSRDRRRSRSHDRS 339

Query: 444 QGAQARRGPRGASRDGGRGRGRGR 467
           +     R  R  SRD  R + R R
Sbjct: 340 E-----RKHRSRSRDRRRSKSRDR 358


>gi|19923485 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 59/264 (22%), Positives = 109/264 (41%), Gaps = 57/264 (21%)

Query: 204 VGASRGMKKLLQEKFPNMSRLQDISELLATGAGLSESEAEPDGDHNITELPQAVAGRGNM 263
           V  ++GM KL+++       L++  ELL +     ES A  +    + E+  A    G+ 
Sbjct: 152 VEEAQGMMKLVEQ-------LKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDA 204

Query: 264 RAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKTEEELQAILEAKEKKLRLKA 323
           ++            R+   L+  Q  +G  K+   + V + +E+L+   E  ++  RLK 
Sbjct: 205 QS------------RVDDHLMGKQH-MGYAKIK--ATVEELKEKLRKRTEEPDRDERLKK 249

Query: 324 QRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELGEDDDEQE 383
           ++Q ++ +  +R++E+ E  RK+  E  ++ +    D E     SR+ S       D   
Sbjct: 250 EKQEREEREKEREREREERERKRRREEEEREKERARDRERRK-RSRSRSRHSSRTSD--- 305

Query: 384 DDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKS 443
                                    +R ++S   KR R   +R R R  D++  ++ D+S
Sbjct: 306 -------------------------RRCSRSRDHKRSR-SRERRRSRSRDRRRSRSHDRS 339

Query: 444 QGAQARRGPRGASRDGGRGRGRGR 467
           +     R  R  SRD  R + R R
Sbjct: 340 E-----RKHRSRSRDRRRSKSRDR 358


>gi|166795262 AE binding protein 2 isoform a [Homo sapiens]
          Length = 503

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 6/107 (5%)

Query: 356 VGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415
           VGG + E    PS  ++ + GED+DE+EDD+ E    +      E    E+  + L  S 
Sbjct: 74  VGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEE----ESSAESLVGSS 129

Query: 416 GRKRKRWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGGRG 462
           G            G           D  +G +  +GPRG+   GG G
Sbjct: 130 GGSSSDETRSLSPGAASSSS--GDGDGKEGLEEPKGPRGSQGGGGGG 174


>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
          Length = 732

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 38/146 (26%), Positives = 62/146 (42%), Gaps = 10/146 (6%)

Query: 234 GAGLSESEAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEG 293
           G G S + + P+G    T LP  +A  G +R  Q   R     P+     +K  E     
Sbjct: 4   GGGGSGTGSRPEGTARGTSLPGKIAEPGAVRTSQPNYR-----PQGMEGFLKSDERQRLA 58

Query: 294 KVMFHSFVSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKK 353
           K              Q ILE K+K+ RL+ ++Q ++      +Q QRE  ++ ++E  +K
Sbjct: 59  KERREEREKCLAAREQQILE-KQKRARLQYEKQMEERWRKLEEQRQREDQKRAAVEEKRK 117

Query: 354 ARVGGSDEEASGIP----SRTASLEL 375
            ++   +E    +      RT  LEL
Sbjct: 118 QKLREEEERLEAMMRRSLERTQQLEL 143



 Score = 32.7 bits (73), Expect = 0.73
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 8/89 (8%)

Query: 303 KTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQR---EAHRKKSLEGMKKARVGGS 359
           + E+E Q  LE +E  L+ KA+ +  + +   RKQE+    +   KK  EG +K + G  
Sbjct: 422 RVEKEEQDRLEREE--LKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAG-- 477

Query: 360 DEEASGIPSRTASLELGEDDDEQEDDDIE 388
            EEA         L+  ++ ++QE   IE
Sbjct: 478 -EEAKRKAEEELLLKEKQEQEKQEKAMIE 505


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 28/124 (22%), Positives = 61/124 (49%), Gaps = 3/124 (2%)

Query: 299  SFVSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGG 358
            S  S+ EEE +   E +E+++R + + + ++ +  +++ E+ E  +KK  +  KK  V  
Sbjct: 2242 SLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQE 2301

Query: 359  SD---EEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSP 415
             +   EE   I S   +  L ++++E+E   +E       E   ++   + +++R     
Sbjct: 2302 KEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLR 2361

Query: 416  GRKR 419
            GR+R
Sbjct: 2362 GRER 2365



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 39/173 (22%), Positives = 81/173 (46%), Gaps = 26/173 (15%)

Query: 294  KVMFHSFVSKTE------EELQAILEAKEKKLRLKAQRQAQQAQNVQRKQE---QREAHR 344
            K  F S V + E      EE++++L+  EK+  L ++ + ++ +  +R++E   + E  R
Sbjct: 2210 KEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEER 2269

Query: 345  KKSLEGMKKARVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFP 404
            K+  EG +K +V   +EE      +    E  +++ +++++  E   + + E  +E L  
Sbjct: 2270 KEEEEGEEK-QVEKEEEE-----KKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSD 2323

Query: 405  EAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASR 457
            E +++             E+DR +  L  +K  K ++     Q R+  RG  R
Sbjct: 2324 EEEEEESCS------LEEEVDREKEILKKEKQFKLQE-----QRRKSLRGRER 2365


>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
           sapiens]
          Length = 437

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 38/158 (24%), Positives = 64/158 (40%), Gaps = 17/158 (10%)

Query: 315 KEKKLRLKAQRQAQQAQNVQRKQEQREAH-RKKSLEGMKKARVGGSDEEASGIPSRTASL 373
           KE++ R    R  ++    + K+E+R +  R K  +  +K R   S E A     R   L
Sbjct: 250 KERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEEL 309

Query: 374 ELGEDDDEQEDDDIEYFCQAVGEAPSED-----LFPEAKQKRLAKSPGRKRKRWEMDRGR 428
             G  D  +  +         G+AP +D     L P+       K   R R+R    R  
Sbjct: 310 RGGGGDMAEPSE--------AGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSE 361

Query: 429 GRLCDQKFPKTKDKSQGAQARRGPRGASRDGGRGRGRG 466
               +++  + +D+ +  + +RG RG+ R     RG G
Sbjct: 362 R---ERRRDRDRDRDRDREHKRGERGSERGRDEARGGG 396


>gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 [Homo
            sapiens]
          Length = 2542

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 25/73 (34%), Positives = 42/73 (57%), Gaps = 7/73 (9%)

Query: 317  KKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELG 376
            K+L L+  R+  + Q +  K+E+R+  RKK  E  K+ +    +E+    P   +  EL 
Sbjct: 1433 KELDLEKSREESRKQALAAKREKRKEKRKKKKEEQKRKQ----EEDEENKPKENS--ELP 1486

Query: 377  EDDDEQE-DDDIE 388
            ED+DE+E D+D+E
Sbjct: 1487 EDEDEEENDEDVE 1499


>gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens]
          Length = 2617

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 25/73 (34%), Positives = 42/73 (57%), Gaps = 7/73 (9%)

Query: 317  KKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELG 376
            K+L L+  R+  + Q +  K+E+R+  RKK  E  K+ +    +E+    P   +  EL 
Sbjct: 1433 KELDLEKSREESRKQALAAKREKRKEKRKKKKEEQKRKQ----EEDEENKPKENS--ELP 1486

Query: 377  EDDDEQE-DDDIE 388
            ED+DE+E D+D+E
Sbjct: 1487 EDEDEEENDEDVE 1499


>gi|213385278 TNF receptor-associated factor 3 interacting protein 1
           isoform 2 [Homo sapiens]
          Length = 625

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 42/161 (26%), Positives = 71/161 (44%), Gaps = 11/161 (6%)

Query: 313 EAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTAS 372
           E  E K R     ++Q+  N   ++E+   H  K+ E    A +    +E S    R   
Sbjct: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVH--KNTEDRGDAEI----KERSTSRDRKQK 185

Query: 373 LELGEDDDEQEDD-DIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRKRWEMDRGRGRL 431
            EL ED   +E D D E   +  G    E    E ++ +    P  +R++   +R R R 
Sbjct: 186 EELKEDRKPREKDKDKEKAKENGGNRHREG---ERERAKARARPDNERQKDRGNRERDRD 242

Query: 432 CDQKFPKTKDKSQGAQARRGPRGASRDGGRGRGRGRPGKRV 472
            ++K  +T+ KS+G + +   R   R+  R +G+ R  +RV
Sbjct: 243 SERK-KETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRV 282


>gi|20070262 TNF receptor-associated factor 3 interacting protein 1
           isoform 1 [Homo sapiens]
          Length = 691

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 42/161 (26%), Positives = 71/161 (44%), Gaps = 11/161 (6%)

Query: 313 EAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTAS 372
           E  E K R     ++Q+  N   ++E+   H  K+ E    A +    +E S    R   
Sbjct: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVH--KNTEDRGDAEI----KERSTSRDRKQK 185

Query: 373 LELGEDDDEQEDD-DIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRKRWEMDRGRGRL 431
            EL ED   +E D D E   +  G    E    E ++ +    P  +R++   +R R R 
Sbjct: 186 EELKEDRKPREKDKDKEKAKENGGNRHREG---ERERAKARARPDNERQKDRGNRERDRD 242

Query: 432 CDQKFPKTKDKSQGAQARRGPRGASRDGGRGRGRGRPGKRV 472
            ++K  +T+ KS+G + +   R   R+  R +G+ R  +RV
Sbjct: 243 SERK-KETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRV 282


>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
          Length = 1233

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 41/191 (21%)

Query: 303 KTEEELQAILEAKEKKLRLKAQRQAQQAQNVQ--------RKQEQREAHRKKSLEGMKKA 354
           + E E +  LEA+E++ RL+AQ QA++ + ++        R+QE+ E    + L+  ++ 
Sbjct: 305 RREREERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQEEE 364

Query: 355 RVGGSDE------EASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDL------ 402
              G +E      E  G P        G    E+ED   E   +  G+A  ED       
Sbjct: 365 EAEGWEELEQQEAEVQGPPEALEETGEGRRGAEEEDLGEE---EEEGQAHLEDWRGQLSE 421

Query: 403 ----FPEAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRD 458
               F E  + +    P  +R+  E       +C+++ P+       A+ RR  +G S  
Sbjct: 422 LLNDFEERLEDQERLKPEGQREHSE----EPGICEEQNPE-------AERRREQQGRS-- 468

Query: 459 GGRGRGRGRPG 469
            G  +G  RPG
Sbjct: 469 -GDFQGADRPG 478



 Score = 34.3 bits (77), Expect = 0.25
 Identities = 42/193 (21%), Positives = 80/193 (41%), Gaps = 20/193 (10%)

Query: 291 GEGKVMFHSFVSKT--EEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQR-------- 340
           GE K  +H         EE +   E   ++L  K +RQ  +A   +R +EQR        
Sbjct: 201 GEDKPTWHEEEPNPLDSEEERRRQEDYWRELEAKCKRQKAEAAEKRRLEEQRLQALERRL 260

Query: 341 --EAHRKKSLEGMKKARVGGSDEEASGIPSRTASLEL-GEDDDEQEDDDIEYFCQAVGEA 397
             E  R++ LE   + +    + E +    +  SLE  G +D E+ + +     +A  E 
Sbjct: 261 WEENRRQELLEEEGEGQEPPLEAERAPREEQQRSLEAPGWEDAERREREERERLEAEEER 320

Query: 398 PSEDLFPEAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQGAQAR-------R 450
                  +A+++R  +   R  +R   +   GR  ++   + +++++G +         +
Sbjct: 321 RRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQEEEEAEGWEELEQQEAEVQ 380

Query: 451 GPRGASRDGGRGR 463
           GP  A  + G GR
Sbjct: 381 GPPEALEETGEGR 393


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 32/156 (20%), Positives = 67/156 (42%), Gaps = 3/156 (1%)

Query: 317 KKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELG 376
           K    K++ +++     + K   R   R +S +  +K+R    ++  S   S   S    
Sbjct: 212 KSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKK--EKSRSPSKEKSRSRSHSAGKSRSKS 269

Query: 377 EDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKF 436
           +D  E++  + +   +    +PS        + R  +    + KR  + RGR +    + 
Sbjct: 270 KDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQ 329

Query: 437 PKTKDKSQ-GAQARRGPRGASRDGGRGRGRGRPGKR 471
            +++ +S+ G+++R   R  S+D  +GR R R   R
Sbjct: 330 SRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESR 365



 Score = 33.9 bits (76), Expect = 0.33
 Identities = 34/184 (18%), Positives = 74/184 (40%), Gaps = 12/184 (6%)

Query: 292 EGKVMFHSFVSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSL-EG 350
           E K+  +  V K +    +  ++K K    +++ Q ++ +  +R    R   ++KSL + 
Sbjct: 274 EEKIQNNDNVGKPKSRSPSRHKSKSKS---RSRSQERRVEEEKRGSVSRGRSQEKSLRQS 330

Query: 351 MKKARVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKR 410
             ++R  G     S   S++     G     +E        ++   + SE       ++ 
Sbjct: 331 RSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRS-----RSRSRSKSERSRKRGSKRD 385

Query: 411 LAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGGRG---RGRGR 467
                 +K+K+ + DR + R   +   K ++ ++   ++R  RG S + G     R R R
Sbjct: 386 SKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSR 445

Query: 468 PGKR 471
              +
Sbjct: 446 SNSK 449


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,002,756
Number of Sequences: 37866
Number of extensions: 839839
Number of successful extensions: 8892
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 80
Number of HSP's successfully gapped in prelim test: 354
Number of HSP's that attempted gapping in prelim test: 7227
Number of HSP's gapped (non-prelim): 1423
length of query: 473
length of database: 18,247,518
effective HSP length: 106
effective length of query: 367
effective length of database: 14,233,722
effective search space: 5223775974
effective search space used: 5223775974
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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