Guide to the Human Genome
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Name: DFFA Sequence: fasta or formatted (268aa) NCBI GI: 47132600
Description:

DNA fragmentation factor, 45kDa, alpha polypeptide isoform 2

Referenced in:

BCL2 Pathways, Caspases, and Programmed Cell Death

Other entries for this name:
alt prot [331aa] DNA fragmentation factor, 45kDa, alpha polypeptide isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.6         23           2
 C cysteine            2.2          6           1
 D aspartate           8.2         22           4
 E glutamate           9.3         25           2
 F phenylalanine       1.5          4           1
 G glycine             5.6         15           2
 H histidine           1.5          4           1
 I isoleucine          3.4          9           2
 K lysine              4.9         13           1
 L leucine            13.8         37           2
 M methionine          0.7          2           1
 N asparagine          2.6          7           2
 P proline             2.2          6           1
 Q glutamine           7.1         19           2
 R arginine            4.5         12           2
 S serine             10.1         27           2
 T threonine           4.9         13           1
 V valine              6.3         17           1
 W tryptophan          1.1          3           1
 Y tyrosine            1.5          4           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   DNA fragmentation factor, 45kDa, alpha polypeptide i... 
DFFA                  0.968   DNA fragmentation factor, 45kDa, alpha polypeptide is...
CIDEA                 0.066   cell death-inducing DFFA-like effector a isoform 2 [...
CIDEA                 0.066   cell death-inducing DFFA-like effector a isoform 1 [H...
CIDEC                 0.050   cell death-inducing DFFA-like effector c 
CIDEB                 0.042   cell death-inducing DFFA-like effector b 
GOLGA4                0.026   golgi autoantigen, golgin subfamily a, 4 
HOOK1                 0.022   hook homolog 1 
CGN                   0.022   cingulin 
CROCC                 0.020   ciliary rootlet coiled-coil 
KRT77                 0.018   keratin 77 
EEA1                  0.018   early endosome antigen 1, 162kD 
EPS15L1               0.018   epidermal growth factor receptor pathway substrate 1...
GOLGA3                0.018   Golgi autoantigen, golgin subfamily a, 3 
GOLGA6D               0.016   golgi autoantigen, golgin subfamily a, 6D 
GOLGA6C               0.016   PREDICTED: golgi autoantigen, golgin subfamily a, 6C...
DFFB                  0.016   DNA fragmentation factor, 40 kD, beta polypeptide [Ho...
CCHCR1                0.016   coiled-coil alpha-helical rod protein 1 isoform 1 [...
CCHCR1                0.016   coiled-coil alpha-helical rod protein 1 isoform 2 [...
CCHCR1                0.016   coiled-coil alpha-helical rod protein 1 isoform 3 [...
CEP135                0.016   centrosome protein 4 
GOLGA6                0.016   golgi autoantigen, golgin subfamily a, 6 
VIM                   0.014   vimentin 
GOLGA6B               0.014   golgi autoantigen, golgin subfamily a, 6B 
PIBF1                 0.014   progesterone-induced blocking factor 1 
SDCCAG8               0.014   serologically defined colon cancer antigen 8 
EPS15                 0.014   epidermal growth factor receptor pathway substrate ...
EPS15                 0.014   epidermal growth factor receptor pathway substrate 15...
ERC1                  0.014   RAB6-interacting protein 2 isoform epsilon 
LZTS1                 0.014   leucine zipper, putative tumor suppressor 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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