Guide to the Human Genome
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Name: DFFA Sequence: fasta or formatted (331aa) NCBI GI: 4758148
Description:

DNA fragmentation factor, 45kDa, alpha polypeptide isoform 1

Referenced in:

BCL2 Pathways, Caspases, and Programmed Cell Death

Other entries for this name:
alt prot [268aa] DNA fragmentation factor, 45kDa, alpha polypeptide isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.4         31           2
 C cysteine            2.1          7           1
 D aspartate           7.9         26           4
 E glutamate           9.1         30           2
 F phenylalanine       1.2          4           1
 G glycine             3.9         13           2
 H histidine           1.2          4           1
 I isoleucine          3.3         11           2
 K lysine              5.7         19           2
 L leucine            13.9         46           2
 M methionine          0.6          2           1
 N asparagine          2.4          8           2
 P proline             3.3         11           2
 Q glutamine           7.3         24           2
 R arginine            5.1         17           2
 S serine             10.0         33           2
 T threonine           5.4         18           1
 V valine              5.7         19           1
 W tryptophan          1.2          4           1
 Y tyrosine            1.2          4           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   DNA fragmentation factor, 45kDa, alpha polypeptide is... 
DFFA                  0.780   DNA fragmentation factor, 45kDa, alpha polypeptide i...
CIDEA                 0.053   cell death-inducing DFFA-like effector a isoform 2 [...
CIDEA                 0.053   cell death-inducing DFFA-like effector a isoform 1 [H...
CIDEC                 0.040   cell death-inducing DFFA-like effector c 
CIDEB                 0.034   cell death-inducing DFFA-like effector b 
GOLGA4                0.029   golgi autoantigen, golgin subfamily a, 4 
MYH15                 0.026   myosin, heavy polypeptide 15 
MYH3                  0.023   myosin, heavy chain 3, skeletal muscle, embryonic [H...
FYCO1                 0.023   FYVE and coiled-coil domain containing 1 
EEA1                  0.023   early endosome antigen 1, 162kD 
GOLGA6B               0.023   golgi autoantigen, golgin subfamily a, 6B 
GOLGA6D               0.019   golgi autoantigen, golgin subfamily a, 6D 
GOLGA6C               0.019   PREDICTED: golgi autoantigen, golgin subfamily a, 6C...
GOLGA6                0.019   golgi autoantigen, golgin subfamily a, 6 
NUMA1                 0.019   nuclear mitotic apparatus protein 1 
CCDC89                0.019   coiled-coil domain containing 89 
CEP164                0.018   centrosomal protein 164kDa 
HOOK1                 0.018   hook homolog 1 
CGN                   0.018   cingulin 
EPS15                 0.016   epidermal growth factor receptor pathway substrate ...
EPS15                 0.016   epidermal growth factor receptor pathway substrate 15...
LZTS1                 0.016   leucine zipper, putative tumor suppressor 1 
CAGE1                 0.016   cancer antigen 1 
C19orf29              0.016   chromosome 19 open reading frame 29 
C19orf29              0.016   chromosome 19 open reading frame 29 
EPS15L1               0.016   epidermal growth factor receptor pathway substrate 1...
GOLGA3                0.016   Golgi autoantigen, golgin subfamily a, 3 
CROCC                 0.016   ciliary rootlet coiled-coil 
CENPF                 0.015   centromere protein F 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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