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Search of human proteins with 47106067
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47106067 transmembrane emp24 protein transport domain
containing 8 [Homo sapiens]
(325 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47106067 transmembrane emp24 protein transport domain contain... 660 0.0
gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo sa... 197 1e-50
gi|28376621 SEC14p-like protein TAP3 isoform a [Homo sapiens] 40 0.003
gi|7110715 SEC14-like 2 isoform 1 [Homo sapiens] 40 0.004
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 39 0.005
gi|169167074 PREDICTED: similar to SET translocation [Homo sapiens] 39 0.006
gi|169166810 PREDICTED: similar to SET translocation [Homo sapiens] 39 0.006
gi|169166302 PREDICTED: similar to SET translocation [Homo sapiens] 39 0.006
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 39 0.006
gi|27923592 SEC14-like 3 [Homo sapiens] 39 0.008
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 37 0.018
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 37 0.018
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 37 0.018
gi|139394621 chondroitin sulfate proteoglycan 5 (neuroglycan C) ... 37 0.024
gi|24850133 protein inhibitor of activated STAT, 4 [Homo sapiens] 37 0.031
gi|55956788 nucleolin [Homo sapiens] 35 0.070
gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo ... 35 0.091
gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo ... 35 0.091
gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo ... 35 0.091
gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo ... 35 0.091
gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo ... 35 0.091
gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo ... 35 0.091
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 35 0.12
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 35 0.12
gi|22027653 adaptor-related protein complex 1 beta 1 subunit iso... 34 0.16
gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens] 34 0.16
gi|38788219 zinc finger protein 428 [Homo sapiens] 33 0.26
gi|151101459 SAPS domain family, member 1 [Homo sapiens] 33 0.26
gi|19923312 v-myc myelocytomatosis viral related oncogene, neuro... 33 0.35
gi|25952134 dispatched A [Homo sapiens] 33 0.35
>gi|47106067 transmembrane emp24 protein transport domain containing
8 [Homo sapiens]
Length = 325
Score = 660 bits (1703), Expect = 0.0
Identities = 325/325 (100%), Positives = 325/325 (100%)
Query: 1 MSDLQAAEGPGSWSPTARPGSAGGVGDCQGVEGSQAAASENEDLENKDTSLLASATDPEP 60
MSDLQAAEGPGSWSPTARPGSAGGVGDCQGVEGSQAAASENEDLENKDTSLLASATDPEP
Sbjct: 1 MSDLQAAEGPGSWSPTARPGSAGGVGDCQGVEGSQAAASENEDLENKDTSLLASATDPEP 60
Query: 61 CSSPHRPQMVSPVSKDATEDLRKATGPLEAQALVKQDLLPADQAQVLNEMAKYQVPQRSG 120
CSSPHRPQMVSPVSKDATEDLRKATGPLEAQALVKQDLLPADQAQVLNEMAKYQVPQRSG
Sbjct: 61 CSSPHRPQMVSPVSKDATEDLRKATGPLEAQALVKQDLLPADQAQVLNEMAKYQVPQRSG 120
Query: 121 DIVMIQSEHTGAIDVLSADLESADLLGDHRKVSPPLMAPPCIWTFAKVKEFKSKLGKEKN 180
DIVMIQSEHTGAIDVLSADLESADLLGDHRKVSPPLMAPPCIWTFAKVKEFKSKLGKEKN
Sbjct: 121 DIVMIQSEHTGAIDVLSADLESADLLGDHRKVSPPLMAPPCIWTFAKVKEFKSKLGKEKN 180
Query: 181 SRLVVKRGEVVTIRVPTHPEGKRVCWEFATDDYDIGFGVYFDWTPVTSTDITVQVSDSSD 240
SRLVVKRGEVVTIRVPTHPEGKRVCWEFATDDYDIGFGVYFDWTPVTSTDITVQVSDSSD
Sbjct: 181 SRLVVKRGEVVTIRVPTHPEGKRVCWEFATDDYDIGFGVYFDWTPVTSTDITVQVSDSSD 240
Query: 241 DEDEEEEEEEEIEEPVPAGDVERGSRSSLRGRYGEVMPVYRRDSHRDVQAGSHDYPGEGI 300
DEDEEEEEEEEIEEPVPAGDVERGSRSSLRGRYGEVMPVYRRDSHRDVQAGSHDYPGEGI
Sbjct: 241 DEDEEEEEEEEIEEPVPAGDVERGSRSSLRGRYGEVMPVYRRDSHRDVQAGSHDYPGEGI 300
Query: 301 YLLKFDNSYSLLRNKTLYFHIYYTS 325
YLLKFDNSYSLLRNKTLYFHIYYTS
Sbjct: 301 YLLKFDNSYSLLRNKTLYFHIYYTS 325
>gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo
sapiens]
Length = 528
Score = 197 bits (501), Expect = 1e-50
Identities = 98/230 (42%), Positives = 145/230 (63%), Gaps = 9/230 (3%)
Query: 95 KQDLLPADQAQVLNEMAKYQVPQRSGDIVMIQSEHTGAIDVLSADLESADLLGDHRKVSP 154
+Q+++ A + + VP + HT + + + + L + K S
Sbjct: 307 QQEVVVAGSSLPTSSKVNATVPSNMMSVNGQAKTHTDSSEKELEPEAAEEALENGPKESL 366
Query: 155 PLMAPPCIWTFAKVKEFKSKLGKEKNSRLVVKRGEVVTIRVPTHPEGKRVCWEFATDDYD 214
P++A P +WT ++K+FK K+ ++ +S + V RGEVVT+RVPTH EG + WEFATD+YD
Sbjct: 367 PVIAAPSMWTRPQIKDFKEKIQQDADSVITVGRGEVVTVRVPTHEEGSYLFWEFATDNYD 426
Query: 215 IGFGVYFDWTPVTSTDITVQVSDSSDDEDEEEEEEEEIEEPVPAGDVERGSRSSLRGRYG 274
IGFGVYF+WT +T ++V VS+SSDD++EEEE G E+ +++ +
Sbjct: 427 IGFGVYFEWTDSPNTAVSVHVSESSDDDEEEEEN---------IGCEEKAKKNANKPLLD 477
Query: 275 EVMPVYRRDSHRDVQAGSHDYPGEGIYLLKFDNSYSLLRNKTLYFHIYYT 324
E++PVYRRD H +V AGSH YPG G+YLLKFDNSYSL R+K++Y+ +YYT
Sbjct: 478 EIVPVYRRDCHEEVYAGSHQYPGRGVYLLKFDNSYSLWRSKSVYYRVYYT 527
>gi|28376621 SEC14p-like protein TAP3 isoform a [Homo sapiens]
Length = 406
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/116 (25%), Positives = 46/116 (39%), Gaps = 39/116 (33%)
Query: 206 WEFATDDYDIGFGVYFDWTPVTSTDITVQVSDSSDDEDEEEEEEEEIEEPVPAGDVERGS 265
W+FA+D DIGFGV+ + G
Sbjct: 305 WQFASDGGDIGFGVFLK--------------------------------------TKMGE 326
Query: 266 RSSLRGRYGEVMPVYRRDSHRDVQAGSHDYPGEGIYLLKFDNSYSLLRNKTLYFHI 321
+ S R EV+P R ++H + GS G+Y+L+FDN+YS + K L + +
Sbjct: 327 QQSAR-EMTEVLPSQRYNAHMVPEDGSLTCLQAGVYVLRFDNTYSRMHAKKLSYTV 381
>gi|7110715 SEC14-like 2 isoform 1 [Homo sapiens]
Length = 403
Score = 39.7 bits (91), Expect = 0.004
Identities = 28/116 (24%), Positives = 45/116 (38%), Gaps = 39/116 (33%)
Query: 206 WEFATDDYDIGFGVYFDWTPVTSTDITVQVSDSSDDEDEEEEEEEEIEEPVPAGDVERGS 265
W+F +D D+GFG++ G+ +R
Sbjct: 305 WQFMSDGADVGFGIFLK---------------------------------TKMGERQRA- 330
Query: 266 RSSLRGRYGEVMPVYRRDSHRDVQAGSHDYPGEGIYLLKFDNSYSLLRNKTLYFHI 321
G EV+P R +SH + G+ GIY+L+FDN+YS + K + F +
Sbjct: 331 -----GEMTEVLPNQRYNSHLVPEDGTLTCSDPGIYVLRFDNTYSFIHAKKVNFTV 381
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 39.3 bits (90), Expect = 0.005
Identities = 18/45 (40%), Positives = 25/45 (55%)
Query: 237 DSSDDEDEEEEEEEEIEEPVPAGDVERGSRSSLRGRYGEVMPVYR 281
D DE+EEEEEEEE EE + R ++RG++ + P R
Sbjct: 1256 DDESDEEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKHSVIPPAAR 1300
>gi|169167074 PREDICTED: similar to SET translocation [Homo sapiens]
Length = 309
Score = 38.9 bits (89), Expect = 0.006
Identities = 32/112 (28%), Positives = 45/112 (40%), Gaps = 2/112 (1%)
Query: 166 AKVKEFKSKLGKEKNSRLVVKRGEVVTIRVPTHPEGKRVCWEFATDDY--DIGFGVYFDW 223
+K E K K GK+ RL + + R PE + +D D+G + D
Sbjct: 192 SKSTEIKWKSGKDVTKRLSQMQNKASRKRQHEAPESFLTWFTDHSDAGADDLGEDIKDDI 251
Query: 224 TPVTSTDITVQVSDSSDDEDEEEEEEEEIEEPVPAGDVERGSRSSLRGRYGE 275
P V D + ED+ EEEEE +E+ GD + G G GE
Sbjct: 252 WPNPLQYYLVPHMDDEEGEDDNEEEEEGLEDTDEEGDEDEGEEDDDEGEEGE 303
>gi|169166810 PREDICTED: similar to SET translocation [Homo sapiens]
Length = 309
Score = 38.9 bits (89), Expect = 0.006
Identities = 32/112 (28%), Positives = 45/112 (40%), Gaps = 2/112 (1%)
Query: 166 AKVKEFKSKLGKEKNSRLVVKRGEVVTIRVPTHPEGKRVCWEFATDDY--DIGFGVYFDW 223
+K E K K GK+ RL + + R PE + +D D+G + D
Sbjct: 192 SKSTEIKWKSGKDVTKRLSQMQNKASRKRQHEAPESFLTWFTDHSDAGADDLGEDIKDDI 251
Query: 224 TPVTSTDITVQVSDSSDDEDEEEEEEEEIEEPVPAGDVERGSRSSLRGRYGE 275
P V D + ED+ EEEEE +E+ GD + G G GE
Sbjct: 252 WPNPLQYYLVPHMDDEEGEDDNEEEEEGLEDTDEEGDEDEGEEDDDEGEEGE 303
>gi|169166302 PREDICTED: similar to SET translocation [Homo sapiens]
Length = 296
Score = 38.9 bits (89), Expect = 0.006
Identities = 32/112 (28%), Positives = 45/112 (40%), Gaps = 2/112 (1%)
Query: 166 AKVKEFKSKLGKEKNSRLVVKRGEVVTIRVPTHPEGKRVCWEFATDDY--DIGFGVYFDW 223
+K E K K GK+ RL + + R PE + +D D+G + D
Sbjct: 179 SKSTEIKWKSGKDVTKRLSQMQNKASRKRQHEAPESFLTWFTDHSDAGADDLGEDIKDDI 238
Query: 224 TPVTSTDITVQVSDSSDDEDEEEEEEEEIEEPVPAGDVERGSRSSLRGRYGE 275
P V D + ED+ EEEEE +E+ GD + G G GE
Sbjct: 239 WPNPLQYYLVPHMDDEEGEDDNEEEEEGLEDTDEEGDEDEGEEDDDEGEEGE 290
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 38.9 bits (89), Expect = 0.006
Identities = 24/55 (43%), Positives = 28/55 (50%), Gaps = 3/55 (5%)
Query: 237 DSSDDEDEEEEEEEEIEEPVPAGDVERG---SRSSLRGRYGEVMPVYRRDSHRDV 288
+ D+E+EEEEEEEE EEP G E+ SR L GE PV DV
Sbjct: 380 EEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTGEPAPVLSSPPPADV 434
Score = 30.4 bits (67), Expect = 2.2
Identities = 14/16 (87%), Positives = 14/16 (87%)
Query: 239 SDDEDEEEEEEEEIEE 254
SDDEDEEEEEE E EE
Sbjct: 358 SDDEDEEEEEEGEEEE 373
>gi|27923592 SEC14-like 3 [Homo sapiens]
Length = 400
Score = 38.5 bits (88), Expect = 0.008
Identities = 27/116 (23%), Positives = 46/116 (39%), Gaps = 39/116 (33%)
Query: 206 WEFATDDYDIGFGVYFDWTPVTSTDITVQVSDSSDDEDEEEEEEEEIEEPVPAGDVERGS 265
W+F++D DIGFGV+ G+ +R
Sbjct: 305 WQFSSDGADIGFGVFLK---------------------------------TKMGERQRA- 330
Query: 266 RSSLRGRYGEVMPVYRRDSHRDVQAGSHDYPGEGIYLLKFDNSYSLLRNKTLYFHI 321
G +V+P R ++H + G+ G+Y+L+FDN+YS + K + F +
Sbjct: 331 -----GEMTDVLPSQRYNAHMVPEDGNLTCSEAGVYVLRFDNTYSFVHAKKVSFTV 381
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
isoform b [Homo sapiens]
Length = 1176
Score = 37.4 bits (85), Expect = 0.018
Identities = 23/57 (40%), Positives = 34/57 (59%), Gaps = 3/57 (5%)
Query: 231 ITVQVSDSSDDEDEEE-EEEEEIEEPVPAGDVERGSRSSLRGRYG--EVMPVYRRDS 284
+T Q+S+ ++E+EEE EEEEE EE D E G++S G G + +R+DS
Sbjct: 294 LTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDS 350
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
isoform a [Homo sapiens]
Length = 1210
Score = 37.4 bits (85), Expect = 0.018
Identities = 23/57 (40%), Positives = 34/57 (59%), Gaps = 3/57 (5%)
Query: 231 ITVQVSDSSDDEDEEE-EEEEEIEEPVPAGDVERGSRSSLRGRYG--EVMPVYRRDS 284
+T Q+S+ ++E+EEE EEEEE EE D E G++S G G + +R+DS
Sbjct: 294 LTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDS 350
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 37.4 bits (85), Expect = 0.018
Identities = 18/30 (60%), Positives = 22/30 (73%)
Query: 225 PVTSTDITVQVSDSSDDEDEEEEEEEEIEE 254
P D+TV +SSD+E+EEEEEEEE EE
Sbjct: 872 PALEEDLTVININSSDEEEEEEEEEEEEEE 901
Score = 33.5 bits (75), Expect = 0.26
Identities = 15/26 (57%), Positives = 19/26 (73%)
Query: 229 TDITVQVSDSSDDEDEEEEEEEEIEE 254
T I + SD ++E+EEEEEEEE EE
Sbjct: 879 TVININSSDEEEEEEEEEEEEEEEEE 904
Score = 30.4 bits (67), Expect = 2.2
Identities = 14/36 (38%), Positives = 23/36 (63%), Gaps = 4/36 (11%)
Query: 234 QVSDSSDDEDEEEEEE----EEIEEPVPAGDVERGS 265
++ + ++EDEEEEEE E++E G+VE G+
Sbjct: 941 ELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGA 976
>gi|139394621 chondroitin sulfate proteoglycan 5 (neuroglycan C)
precursor [Homo sapiens]
Length = 539
Score = 37.0 bits (84), Expect = 0.024
Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 11/67 (16%)
Query: 198 HP--EGKRVCWEFATDDYDIGFGVYFDWTPVTSTDITVQVSDSSDDEDEEEEEEEEIEEP 255
HP EG+ W +Y D+TP +D S DD DEEEEEEE+ ++
Sbjct: 238 HPDTEGETPSWSL--------LDLYDDFTPFDESDFYPTTS-FYDDLDEEEEEEEDDKDA 288
Query: 256 VPAGDVE 262
V GD+E
Sbjct: 289 VGGGDLE 295
>gi|24850133 protein inhibitor of activated STAT, 4 [Homo sapiens]
Length = 510
Score = 36.6 bits (83), Expect = 0.031
Identities = 16/28 (57%), Positives = 22/28 (78%)
Query: 230 DITVQVSDSSDDEDEEEEEEEEIEEPVP 257
D+T+ S SS+DE+EEEEEEE+ +E P
Sbjct: 467 DLTLDSSSSSEDEEEEEEEEEDEDEEGP 494
Score = 30.0 bits (66), Expect = 2.9
Identities = 13/24 (54%), Positives = 17/24 (70%)
Query: 231 ITVQVSDSSDDEDEEEEEEEEIEE 254
+ + + SS EDEEEEEEEE +E
Sbjct: 466 VDLTLDSSSSSEDEEEEEEEEEDE 489
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 35.4 bits (80), Expect = 0.070
Identities = 15/20 (75%), Positives = 17/20 (85%)
Query: 237 DSSDDEDEEEEEEEEIEEPV 256
+ DDED+EEEEEEE EEPV
Sbjct: 254 EDDDDEDDEEEEEEEEEEPV 273
Score = 32.0 bits (71), Expect = 0.77
Identities = 13/21 (61%), Positives = 16/21 (76%)
Query: 237 DSSDDEDEEEEEEEEIEEPVP 257
D DD+DE++EEEEE EE P
Sbjct: 252 DDEDDDDEDDEEEEEEEEEEP 272
Score = 30.4 bits (67), Expect = 2.2
Identities = 12/22 (54%), Positives = 15/22 (68%)
Query: 237 DSSDDEDEEEEEEEEIEEPVPA 258
D DD+DEE++ EEE E PA
Sbjct: 195 DEDDDDDEEDDSEEEAMETTPA 216
Score = 30.4 bits (67), Expect = 2.2
Identities = 13/21 (61%), Positives = 15/21 (71%)
Query: 237 DSSDDEDEEEEEEEEIEEPVP 257
D DDE+EEEEEEEE + P
Sbjct: 257 DDEDDEEEEEEEEEEPVKEAP 277
Score = 28.9 bits (63), Expect = 6.5
Identities = 14/51 (27%), Positives = 28/51 (54%), Gaps = 6/51 (11%)
Query: 237 DSSDDEDEEEEEEEEIEEPVPAGDVERGSRSSLRGRYGEVMPVYRRDSHRD 287
D DDED++++EE++ EE +G +++ +V+PV ++ D
Sbjct: 191 DDEDDEDDDDDEEDDSEEEAMETTPAKGKKAA------KVVPVKAKNVAED 235
>gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo
sapiens]
Length = 492
Score = 35.0 bits (79), Expect = 0.091
Identities = 42/188 (22%), Positives = 68/188 (36%), Gaps = 15/188 (7%)
Query: 18 RPGSAGGVGDCQGVEGSQAAASENE---DLENKDTSLLASATDPEPCSSPHRPQMVSPVS 74
R S VG +G+ G Q+A+ + DL T+L S T P S SP S
Sbjct: 175 RRKSEPAVGPPRGL-GDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSPSRAKDRESPRS 233
Query: 75 KDATEDLRKATGPLEAQALVKQDLLPADQAQVLNEMAKYQVPQRSGDIVMI--------- 125
+T + P E + +++ LPA ++ + GD V I
Sbjct: 234 YSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWY 293
Query: 126 QSEHTGAIDVLSADLESADLLGDHRKVSPPLMAPPCIWTFAKVKEFKSKLGKEKNSRLVV 185
+ EH G + + + + L K P PP K + N L +
Sbjct: 294 EGEHHGRVGIF--PISYVEKLTPPEKAQPARPPPPAQPGEIGEAIAKYNFNADTNVELSL 351
Query: 186 KRGEVVTI 193
++G+ V +
Sbjct: 352 RKGDRVIL 359
>gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo
sapiens]
Length = 824
Score = 35.0 bits (79), Expect = 0.091
Identities = 42/188 (22%), Positives = 68/188 (36%), Gaps = 15/188 (7%)
Query: 18 RPGSAGGVGDCQGVEGSQAAASENE---DLENKDTSLLASATDPEPCSSPHRPQMVSPVS 74
R S VG +G+ G Q+A+ + DL T+L S T P S SP S
Sbjct: 507 RRKSEPAVGPPRGL-GDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSPSRAKDRESPRS 565
Query: 75 KDATEDLRKATGPLEAQALVKQDLLPADQAQVLNEMAKYQVPQRSGDIVMI--------- 125
+T + P E + +++ LPA ++ + GD V I
Sbjct: 566 YSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWY 625
Query: 126 QSEHTGAIDVLSADLESADLLGDHRKVSPPLMAPPCIWTFAKVKEFKSKLGKEKNSRLVV 185
+ EH G + + + + L K P PP K + N L +
Sbjct: 626 EGEHHGRVGIF--PISYVEKLTPPEKAQPARPPPPAQPGEIGEAIAKYNFNADTNVELSL 683
Query: 186 KRGEVVTI 193
++G+ V +
Sbjct: 684 RKGDRVIL 691
>gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo
sapiens]
Length = 661
Score = 35.0 bits (79), Expect = 0.091
Identities = 42/188 (22%), Positives = 68/188 (36%), Gaps = 15/188 (7%)
Query: 18 RPGSAGGVGDCQGVEGSQAAASENE---DLENKDTSLLASATDPEPCSSPHRPQMVSPVS 74
R S VG +G+ G Q+A+ + DL T+L S T P S SP S
Sbjct: 344 RRKSEPAVGPPRGL-GDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSPSRAKDRESPRS 402
Query: 75 KDATEDLRKATGPLEAQALVKQDLLPADQAQVLNEMAKYQVPQRSGDIVMI--------- 125
+T + P E + +++ LPA ++ + GD V I
Sbjct: 403 YSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWY 462
Query: 126 QSEHTGAIDVLSADLESADLLGDHRKVSPPLMAPPCIWTFAKVKEFKSKLGKEKNSRLVV 185
+ EH G + + + + L K P PP K + N L +
Sbjct: 463 EGEHHGRVGIF--PISYVEKLTPPEKAQPARPPPPAQPGEIGEAIAKYNFNADTNVELSL 520
Query: 186 KRGEVVTI 193
++G+ V +
Sbjct: 521 RKGDRVIL 528
>gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo
sapiens]
Length = 731
Score = 35.0 bits (79), Expect = 0.091
Identities = 42/188 (22%), Positives = 68/188 (36%), Gaps = 15/188 (7%)
Query: 18 RPGSAGGVGDCQGVEGSQAAASENE---DLENKDTSLLASATDPEPCSSPHRPQMVSPVS 74
R S VG +G+ G Q+A+ + DL T+L S T P S SP S
Sbjct: 414 RRKSEPAVGPPRGL-GDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSPSRAKDRESPRS 472
Query: 75 KDATEDLRKATGPLEAQALVKQDLLPADQAQVLNEMAKYQVPQRSGDIVMI--------- 125
+T + P E + +++ LPA ++ + GD V I
Sbjct: 473 YSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWY 532
Query: 126 QSEHTGAIDVLSADLESADLLGDHRKVSPPLMAPPCIWTFAKVKEFKSKLGKEKNSRLVV 185
+ EH G + + + + L K P PP K + N L +
Sbjct: 533 EGEHHGRVGIF--PISYVEKLTPPEKAQPARPPPPAQPGEIGEAIAKYNFNADTNVELSL 590
Query: 186 KRGEVVTI 193
++G+ V +
Sbjct: 591 RKGDRVIL 598
>gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo
sapiens]
Length = 644
Score = 35.0 bits (79), Expect = 0.091
Identities = 42/188 (22%), Positives = 68/188 (36%), Gaps = 15/188 (7%)
Query: 18 RPGSAGGVGDCQGVEGSQAAASENE---DLENKDTSLLASATDPEPCSSPHRPQMVSPVS 74
R S VG +G+ G Q+A+ + DL T+L S T P S SP S
Sbjct: 327 RRKSEPAVGPPRGL-GDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSPSRAKDRESPRS 385
Query: 75 KDATEDLRKATGPLEAQALVKQDLLPADQAQVLNEMAKYQVPQRSGDIVMI--------- 125
+T + P E + +++ LPA ++ + GD V I
Sbjct: 386 YSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWY 445
Query: 126 QSEHTGAIDVLSADLESADLLGDHRKVSPPLMAPPCIWTFAKVKEFKSKLGKEKNSRLVV 185
+ EH G + + + + L K P PP K + N L +
Sbjct: 446 EGEHHGRVGIF--PISYVEKLTPPEKAQPARPPPPAQPGEIGEAIAKYNFNADTNVELSL 503
Query: 186 KRGEVVTI 193
++G+ V +
Sbjct: 504 RKGDRVIL 511
>gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo
sapiens]
Length = 666
Score = 35.0 bits (79), Expect = 0.091
Identities = 42/188 (22%), Positives = 68/188 (36%), Gaps = 15/188 (7%)
Query: 18 RPGSAGGVGDCQGVEGSQAAASENE---DLENKDTSLLASATDPEPCSSPHRPQMVSPVS 74
R S VG +G+ G Q+A+ + DL T+L S T P S SP S
Sbjct: 349 RRKSEPAVGPPRGL-GDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSPSRAKDRESPRS 407
Query: 75 KDATEDLRKATGPLEAQALVKQDLLPADQAQVLNEMAKYQVPQRSGDIVMI--------- 125
+T + P E + +++ LPA ++ + GD V I
Sbjct: 408 YSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWY 467
Query: 126 QSEHTGAIDVLSADLESADLLGDHRKVSPPLMAPPCIWTFAKVKEFKSKLGKEKNSRLVV 185
+ EH G + + + + L K P PP K + N L +
Sbjct: 468 EGEHHGRVGIF--PISYVEKLTPPEKAQPARPPPPAQPGEIGEAIAKYNFNADTNVELSL 525
Query: 186 KRGEVVTI 193
++G+ V +
Sbjct: 526 RKGDRVIL 533
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens]
Length = 1478
Score = 34.7 bits (78), Expect = 0.12
Identities = 15/46 (32%), Positives = 28/46 (60%)
Query: 276 VMPVYRRDSHRDVQAGSHDYPGEGIYLLKFDNSYSLLRNKTLYFHI 321
++P R +SH++ G GIY+L FDN++S +K +++H+
Sbjct: 1419 LIPTTRCNSHKENIQGQLKVRTPGIYMLIFDNTFSRFVSKKVFYHL 1464
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 34.7 bits (78), Expect = 0.12
Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
Query: 196 PTHPEGKRVCWEFATDDYDIGFGVYFDWTPVTSTDITVQVSDSSDDEDEEEEEEEEIEEP 255
P PE + + DD++ + V + ++V ++ ++E+EEEEEEEE EE
Sbjct: 489 PVEPEEEEDTEDAGLDDWE-AMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEES 547
Query: 256 VPAGDVERGSRSS 268
+ E S S
Sbjct: 548 EEEEEEEGESEGS 560
Score = 30.4 bits (67), Expect = 2.2
Identities = 18/58 (31%), Positives = 27/58 (46%), Gaps = 8/58 (13%)
Query: 222 DWTPVTSTDITVQVSDS--------SDDEDEEEEEEEEIEEPVPAGDVERGSRSSLRG 271
DW + S + T +V + + +E+EEEEEEEE +E + E G G
Sbjct: 505 DWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEG 562
Score = 28.5 bits (62), Expect = 8.5
Identities = 13/26 (50%), Positives = 16/26 (61%)
Query: 237 DSSDDEDEEEEEEEEIEEPVPAGDVE 262
+ +DE+ EEEEEEE E GD E
Sbjct: 540 EEEEDEESEEEEEEEGESEGSEGDEE 565
>gi|22027653 adaptor-related protein complex 1 beta 1 subunit
isoform b [Homo sapiens]
Length = 942
Score = 34.3 bits (77), Expect = 0.16
Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 9/95 (9%)
Query: 67 PQMVSPVSKDATEDLRKATGPLEAQALVKQDLLPADQAQVLNEMAKYQV-PQRSGDIVMI 125
P+ S S ++ E T P A + D++PA Q +L ++ + P SG +
Sbjct: 595 PRTASSESAESPE-----TAPTGAPPGEQPDVIPA-QGDLLGDLLNLDLGPPVSGPPLAT 648
Query: 126 QSEHTGAIDVLSADLESADLLGDHRKVSPPLMAPP 160
S GA+D+L L+S L+G V+PP A P
Sbjct: 649 SSVQMGAVDLLGGGLDS--LIGGTNFVAPPTAAVP 681
>gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]
Length = 224
Score = 34.3 bits (77), Expect = 0.16
Identities = 15/31 (48%), Positives = 22/31 (70%)
Query: 224 TPVTSTDITVQVSDSSDDEDEEEEEEEEIEE 254
+P +S+ ++ D D+E+EEEEEEEE EE
Sbjct: 31 SPSSSSSVSGPDDDEEDEEEEEEEEEEEEEE 61
Score = 32.3 bits (72), Expect = 0.59
Identities = 16/31 (51%), Positives = 20/31 (64%)
Query: 224 TPVTSTDITVQVSDSSDDEDEEEEEEEEIEE 254
T +S + VS DDE++EEEEEEE EE
Sbjct: 27 TSSSSPSSSSSVSGPDDDEEDEEEEEEEEEE 57
Score = 30.0 bits (66), Expect = 2.9
Identities = 12/21 (57%), Positives = 16/21 (76%)
Query: 237 DSSDDEDEEEEEEEEIEEPVP 257
+ ++E+EEEEEEEE EE P
Sbjct: 50 EEEEEEEEEEEEEEEEEEEAP 70
Score = 30.0 bits (66), Expect = 2.9
Identities = 12/21 (57%), Positives = 16/21 (76%)
Query: 237 DSSDDEDEEEEEEEEIEEPVP 257
+ ++E+EEEEEEEE E P P
Sbjct: 52 EEEEEEEEEEEEEEEEEAPPP 72
Score = 29.3 bits (64), Expect = 5.0
Identities = 12/18 (66%), Positives = 15/18 (83%)
Query: 237 DSSDDEDEEEEEEEEIEE 254
D ++E+EEEEEEEE EE
Sbjct: 47 DEEEEEEEEEEEEEEEEE 64
Score = 29.3 bits (64), Expect = 5.0
Identities = 12/21 (57%), Positives = 16/21 (76%)
Query: 237 DSSDDEDEEEEEEEEIEEPVP 257
+ ++E+EEEEEEEE EE P
Sbjct: 51 EEEEEEEEEEEEEEEEEEAPP 71
Score = 28.9 bits (63), Expect = 6.5
Identities = 13/29 (44%), Positives = 19/29 (65%)
Query: 226 VTSTDITVQVSDSSDDEDEEEEEEEEIEE 254
V+ D + + ++E+EEEEEEEE EE
Sbjct: 38 VSGPDDDEEDEEEEEEEEEEEEEEEEEEE 66
>gi|38788219 zinc finger protein 428 [Homo sapiens]
Length = 188
Score = 33.5 bits (75), Expect = 0.26
Identities = 13/29 (44%), Positives = 21/29 (72%)
Query: 227 TSTDITVQVSDSSDDEDEEEEEEEEIEEP 255
+ ++ T+ DS ++EDEEEEEEE ++P
Sbjct: 31 SDSEYTLSEPDSEEEEDEEEEEEETTDDP 59
Score = 29.6 bits (65), Expect = 3.8
Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 6/64 (9%)
Query: 211 DDYDIGFGVYFDWTPVTSTDITVQVSDSSDDEDEEEEEEEEIEEPVPAGDVERGSRSSLR 270
DD D+ G P S+D +S+ +E+E+EEEEEE P D + L
Sbjct: 19 DDEDLSPG------PEHSSDSEYTLSEPDSEEEEDEEEEEEETTDDPEYDPGYKVKQRLG 72
Query: 271 GRYG 274
G G
Sbjct: 73 GGRG 76
>gi|151101459 SAPS domain family, member 1 [Homo sapiens]
Length = 881
Score = 33.5 bits (75), Expect = 0.26
Identities = 17/37 (45%), Positives = 22/37 (59%)
Query: 233 VQVSDSSDDEDEEEEEEEEIEEPVPAGDVERGSRSSL 269
V+ S+D EDEEEE+EEE E+ G RG + L
Sbjct: 662 VRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPL 698
>gi|19923312 v-myc myelocytomatosis viral related oncogene,
neuroblastoma derived [Homo sapiens]
Length = 464
Score = 33.1 bits (74), Expect = 0.35
Identities = 13/19 (68%), Positives = 18/19 (94%)
Query: 235 VSDSSDDEDEEEEEEEEIE 253
+SDS D++DEEE+EEEEI+
Sbjct: 260 LSDSDDEDDEEEDEEEEID 278
Score = 30.4 bits (67), Expect = 2.2
Identities = 13/26 (50%), Positives = 19/26 (73%)
Query: 227 TSTDITVQVSDSSDDEDEEEEEEEEI 252
TS + T+ SD DDE+E+EEEE ++
Sbjct: 254 TSGEDTLSDSDDEDDEEEDEEEEIDV 279
Score = 29.3 bits (64), Expect = 5.0
Identities = 13/32 (40%), Positives = 20/32 (62%)
Query: 237 DSSDDEDEEEEEEEEIEEPVPAGDVERGSRSS 268
D+ D D+E++EEE+ EE + VE+ SS
Sbjct: 258 DTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSS 289
>gi|25952134 dispatched A [Homo sapiens]
Length = 1524
Score = 33.1 bits (74), Expect = 0.35
Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 5/69 (7%)
Query: 41 NEDLENKDTSLLASATDPEP---CSSPHRPQMVSPVSKDATEDLRKATGPLEAQALVKQD 97
N+ + ++S+ SA +P P C H Q ++P K+AT G L+ VK
Sbjct: 8 NDFVVLSNSSIATSAANPSPLTPCDGDHAAQQLTP--KEATRTKVSPNGCLQLNGTVKSS 65
Query: 98 LLPADQAQV 106
LP D ++
Sbjct: 66 FLPLDNQRM 74
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.131 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,640,259
Number of Sequences: 37866
Number of extensions: 656166
Number of successful extensions: 11398
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 262
Number of HSP's successfully gapped in prelim test: 74
Number of HSP's that attempted gapping in prelim test: 7711
Number of HSP's gapped (non-prelim): 2216
length of query: 325
length of database: 18,247,518
effective HSP length: 102
effective length of query: 223
effective length of database: 14,385,186
effective search space: 3207896478
effective search space used: 3207896478
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.