Guide to the Human Genome
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Name: PIAS4 Sequence: fasta or formatted (510aa) NCBI GI: 24850133
Description:

protein inhibitor of activated STAT, 4

Referenced in:

Non-Receptor Tyrosine Kinase Pathways
Ubiquitin and Related Protein Modifications

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.7         29           2
 C cysteine            3.5         18           1
 D aspartate           4.7         24           1
 E glutamate           8.2         42           9
 F phenylalanine       2.0         10           2
 G glycine             6.3         32           4
 H histidine           1.4          7           1
 I isoleucine          3.3         17           2
 K lysine              6.5         33           2
 L leucine            11.8         60           2
 M methionine          2.2         11           1
 N asparagine          3.5         18           2
 P proline             9.0         46           2
 Q glutamine           3.5         18           1
 R arginine            5.3         27           2
 S serine              7.5         38           5
 T threonine           4.1         21           2
 V valine              7.5         38           2
 W tryptophan          0.6          3           1
 Y tyrosine            3.5         18           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   protein inhibitor of activated STAT, 4 
PIAS1                 0.405   protein inhibitor of activated STAT, 1 
PIAS3                 0.402   protein inhibitor of activated STAT, 3 
PIAS2                 0.380   protein inhibitor of activated STAT X isoform alpha ...
PIAS2                 0.380   protein inhibitor of activated STAT X isoform beta [...
ZMIZ1                 0.062   retinoic acid induced 17 
ZMIZ2                 0.062   zinc finger, MIZ-type containing 2 isoform 1 
ZMIZ2                 0.062   zinc finger, MIZ-type containing 2 isoform 2 
PELP1                 0.021   proline, glutamic acid and leucine rich protein 1 [...
NEUROD2               0.021   neurogenic differentiation 2 
SENP3                 0.018   SUMO1/sentrin/SMT3 specific protease 3 
BPTF                  0.018   bromodomain PHD finger transcription factor isoform ...
BPTF                  0.018   bromodomain PHD finger transcription factor isoform ...
HMGB2                 0.017   high-mobility group box 2 
HMGB2                 0.017   high-mobility group box 2 
HMGB2                 0.017   high-mobility group box 2 
TAOK2                 0.017   TAO kinase 2 isoform 1 
TAOK2                 0.017   TAO kinase 2 isoform 2 
MAPK8IP2              0.017   mitogen-activated protein kinase 8 interacting protei...
NPM2                  0.016   nucleoplasmin 2 
CHIC1                 0.015   cysteine-rich hydrophobic domain 1 
DAXX                  0.015   death-domain associated protein isoform a 
DAXX                  0.015   death-domain associated protein isoform a 
DAXX                  0.015   death-domain associated protein isoform b 
NEUROD1               0.014   neurogenic differentiation 1 
NEUROD4               0.014   neurogenic differentiation 4 
RANGAP1               0.014   Ran GTPase activating protein 1 
AEBP2                 0.014   AE binding protein 2 isoform b 
MAPK8IP2              0.014   mitogen-activated protein kinase 8 interacting protei...
AEBP2                 0.014   AE binding protein 2 isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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