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Search of human proteins with 46399200
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46399200 testis-specific bromodomain protein [Homo sapiens]
(947 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46399200 testis-specific bromodomain protein [Homo sapiens] 1876 0.0
gi|46399198 testis-specific bromodomain protein [Homo sapiens] 1876 0.0
gi|164419758 bromodomain containing 2 [Homo sapiens] 654 0.0
gi|4826806 bromodomain containing 2 [Homo sapiens] 654 0.0
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 647 0.0
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 595 e-170
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 586 e-167
gi|93102371 polybromo 1 isoform 2 [Homo sapiens] 94 8e-19
gi|41281917 polybromo 1 isoform 4 [Homo sapiens] 94 8e-19
gi|38788260 bromodomain PHD finger transcription factor isoform ... 84 6e-16
gi|38788274 bromodomain PHD finger transcription factor isoform ... 84 6e-16
gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens] 80 1e-14
gi|50345997 E1A binding protein p300 [Homo sapiens] 77 8e-14
gi|119943102 CREB binding protein isoform b [Homo sapiens] 77 8e-14
gi|119943104 CREB binding protein isoform a [Homo sapiens] 77 8e-14
gi|47419911 transcriptional intermediary factor 1 alpha isoform ... 77 8e-14
gi|47419909 transcriptional intermediary factor 1 alpha isoform ... 77 8e-14
gi|153791535 general control of amino acid synthesis 5-like 2 [H... 75 2e-13
gi|148612882 cat eye syndrome chromosome region, candidate 2 [Ho... 74 8e-13
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 73 1e-12
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 73 1e-12
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 73 1e-12
gi|34996489 pleckstrin homology domain interacting protein [Homo... 67 8e-11
gi|74027251 tripartite motif-containing 33 protein isoform beta ... 65 4e-10
gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens] 65 4e-10
gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens] 65 4e-10
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 64 5e-10
gi|30794372 polybromo 1 isoform 1 [Homo sapiens] 64 7e-10
gi|209977097 tripartite motif-containing 66 [Homo sapiens] 64 9e-10
gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo sa... 63 1e-09
>gi|46399200 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 1876 bits (4859), Expect = 0.0
Identities = 947/947 (100%), Positives = 947/947 (100%)
Query: 1 MSLPSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVK 60
MSLPSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVK
Sbjct: 1 MSLPSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVK 60
Query: 61 LQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQ 120
LQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQ
Sbjct: 61 LQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQ 120
Query: 121 ALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQQEIPSV 180
ALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQQEIPSV
Sbjct: 121 ALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQQEIPSV 180
Query: 181 FPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSPTFTEKSV 240
FPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSPTFTEKSV
Sbjct: 181 FPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSPTFTEKSV 240
Query: 241 ALPPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVD 300
ALPPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVD
Sbjct: 241 ALPPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVD 300
Query: 301 VNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVT 360
VNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVT
Sbjct: 301 VNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVT 360
Query: 361 MARMLQDVFETHFSKIPIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERV 420
MARMLQDVFETHFSKIPIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERV
Sbjct: 361 MARMLQDVFETHFSKIPIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERV 420
Query: 421 KRLAKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRL 480
KRLAKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRL
Sbjct: 421 KRLAKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRL 480
Query: 481 KEKSKRNQPKKRKQQFIGLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSR 540
KEKSKRNQPKKRKQQFIGLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSR
Sbjct: 481 KEKSKRNQPKKRKQQFIGLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSR 540
Query: 541 EPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQ 600
EPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQ
Sbjct: 541 EPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQ 600
Query: 601 ELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSESESSSSDLSSS 660
ELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSESESSSSDLSSS
Sbjct: 601 ELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSESESSSSDLSSS 660
Query: 661 DSSDSESEMFPKFTEVKPNDSPSKENVKKMKNECILPEGRTGVTQIGYCVQDTTSANTTL 720
DSSDSESEMFPKFTEVKPNDSPSKENVKKMKNECILPEGRTGVTQIGYCVQDTTSANTTL
Sbjct: 661 DSSDSESEMFPKFTEVKPNDSPSKENVKKMKNECILPEGRTGVTQIGYCVQDTTSANTTL 720
Query: 721 VHQTTPSHVMPPNHHQLAFNYQELEHLQTVKNISPLQILPPSGDSEQLSNGITVMHPSGD 780
VHQTTPSHVMPPNHHQLAFNYQELEHLQTVKNISPLQILPPSGDSEQLSNGITVMHPSGD
Sbjct: 721 VHQTTPSHVMPPNHHQLAFNYQELEHLQTVKNISPLQILPPSGDSEQLSNGITVMHPSGD 780
Query: 781 SDTTMLESECQAPVQKDIKIKNADSWKSLGKPVKPSGVMKSSDELFNQFRKAAIEKEVKA 840
SDTTMLESECQAPVQKDIKIKNADSWKSLGKPVKPSGVMKSSDELFNQFRKAAIEKEVKA
Sbjct: 781 SDTTMLESECQAPVQKDIKIKNADSWKSLGKPVKPSGVMKSSDELFNQFRKAAIEKEVKA 840
Query: 841 RTQELIRKHLEQNTKELKASQENQRDLGNGLTVESFSNKIQNKCSGEEQKEHQQSSEAQD 900
RTQELIRKHLEQNTKELKASQENQRDLGNGLTVESFSNKIQNKCSGEEQKEHQQSSEAQD
Sbjct: 841 RTQELIRKHLEQNTKELKASQENQRDLGNGLTVESFSNKIQNKCSGEEQKEHQQSSEAQD 900
Query: 901 KSKLWLLKDRDLARQKEQERRRREAMVGTIDMTLQSDIMTMFENNFD 947
KSKLWLLKDRDLARQKEQERRRREAMVGTIDMTLQSDIMTMFENNFD
Sbjct: 901 KSKLWLLKDRDLARQKEQERRRREAMVGTIDMTLQSDIMTMFENNFD 947
>gi|46399198 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 1876 bits (4859), Expect = 0.0
Identities = 947/947 (100%), Positives = 947/947 (100%)
Query: 1 MSLPSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVK 60
MSLPSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVK
Sbjct: 1 MSLPSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVK 60
Query: 61 LQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQ 120
LQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQ
Sbjct: 61 LQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQ 120
Query: 121 ALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQQEIPSV 180
ALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQQEIPSV
Sbjct: 121 ALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQQEIPSV 180
Query: 181 FPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSPTFTEKSV 240
FPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSPTFTEKSV
Sbjct: 181 FPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSPTFTEKSV 240
Query: 241 ALPPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVD 300
ALPPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVD
Sbjct: 241 ALPPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVD 300
Query: 301 VNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVT 360
VNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVT
Sbjct: 301 VNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVT 360
Query: 361 MARMLQDVFETHFSKIPIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERV 420
MARMLQDVFETHFSKIPIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERV
Sbjct: 361 MARMLQDVFETHFSKIPIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERV 420
Query: 421 KRLAKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRL 480
KRLAKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRL
Sbjct: 421 KRLAKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRL 480
Query: 481 KEKSKRNQPKKRKQQFIGLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSR 540
KEKSKRNQPKKRKQQFIGLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSR
Sbjct: 481 KEKSKRNQPKKRKQQFIGLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSR 540
Query: 541 EPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQ 600
EPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQ
Sbjct: 541 EPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQ 600
Query: 601 ELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSESESSSSDLSSS 660
ELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSESESSSSDLSSS
Sbjct: 601 ELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSESESSSSDLSSS 660
Query: 661 DSSDSESEMFPKFTEVKPNDSPSKENVKKMKNECILPEGRTGVTQIGYCVQDTTSANTTL 720
DSSDSESEMFPKFTEVKPNDSPSKENVKKMKNECILPEGRTGVTQIGYCVQDTTSANTTL
Sbjct: 661 DSSDSESEMFPKFTEVKPNDSPSKENVKKMKNECILPEGRTGVTQIGYCVQDTTSANTTL 720
Query: 721 VHQTTPSHVMPPNHHQLAFNYQELEHLQTVKNISPLQILPPSGDSEQLSNGITVMHPSGD 780
VHQTTPSHVMPPNHHQLAFNYQELEHLQTVKNISPLQILPPSGDSEQLSNGITVMHPSGD
Sbjct: 721 VHQTTPSHVMPPNHHQLAFNYQELEHLQTVKNISPLQILPPSGDSEQLSNGITVMHPSGD 780
Query: 781 SDTTMLESECQAPVQKDIKIKNADSWKSLGKPVKPSGVMKSSDELFNQFRKAAIEKEVKA 840
SDTTMLESECQAPVQKDIKIKNADSWKSLGKPVKPSGVMKSSDELFNQFRKAAIEKEVKA
Sbjct: 781 SDTTMLESECQAPVQKDIKIKNADSWKSLGKPVKPSGVMKSSDELFNQFRKAAIEKEVKA 840
Query: 841 RTQELIRKHLEQNTKELKASQENQRDLGNGLTVESFSNKIQNKCSGEEQKEHQQSSEAQD 900
RTQELIRKHLEQNTKELKASQENQRDLGNGLTVESFSNKIQNKCSGEEQKEHQQSSEAQD
Sbjct: 841 RTQELIRKHLEQNTKELKASQENQRDLGNGLTVESFSNKIQNKCSGEEQKEHQQSSEAQD 900
Query: 901 KSKLWLLKDRDLARQKEQERRRREAMVGTIDMTLQSDIMTMFENNFD 947
KSKLWLLKDRDLARQKEQERRRREAMVGTIDMTLQSDIMTMFENNFD
Sbjct: 901 KSKLWLLKDRDLARQKEQERRRREAMVGTIDMTLQSDIMTMFENNFD 947
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 654 bits (1686), Expect = 0.0
Identities = 384/745 (51%), Positives = 488/745 (65%), Gaps = 94/745 (12%)
Query: 13 NPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKN 72
NPPPPE N KK GR+TNQLQYL KVV+K LWKH F+WPF++PVDAVKL LPDY+ IIK
Sbjct: 60 NPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQ 119
Query: 73 PMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQ 132
PMD+ TIK+RLEN YY ASEC++DFNTMF+NCY+YNKP DDIVLMAQ LEK+F+QK++
Sbjct: 120 PMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVAS 179
Query: 133 MPQEEQVVGV---KERIKKGTQQNI---AVSSAKEK---SSPSATEKVFKQQEIPSVF-- 181
MPQEEQ + V K KKG + +V+SA + SS S T EIP+
Sbjct: 180 MPQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAVSSVSHTALYTPPPEIPTTVLN 239
Query: 182 ---PKTSISPL-NVVQGASVNSSSQTAAQVT------KGVKRKADTTTPATSAVKA-SSE 230
P SPL + A + TAA KGVKRKADTTTP +A+ A S
Sbjct: 240 IPHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSP 299
Query: 231 FSP--TFTEKSVALPPIKENM------PKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKE 282
SP + K+ LPP++ P+ LPDSQQQ+ K K++EQL+HC+ ILKE
Sbjct: 300 ASPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKE 359
Query: 283 MLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVR 342
+L+KKH +YAWPFY PVD +ALGLH+Y+D++K+PMDL T+K KM+N++Y+DA +FAADVR
Sbjct: 360 LLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVR 419
Query: 343 LMFMNCYKYNPPDHEVVTMARMLQDVFETHFSKIPIEPVESMPLCY-------IKTDITE 395
LMF NCYKYNPPDH+VV MAR LQDVFE ++K+P EP+E PL + +E
Sbjct: 420 LMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSE 479
Query: 396 TTGRENTNEASSEG-------------NSSDDSEDERVKRLAKLQEQLKAVHQQLQVLSQ 442
++ E+++E+SSE + S DSE+ER RLA+LQEQL+AVH+QL LSQ
Sbjct: 480 SSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQ 539
Query: 443 VPFRKLNKKKEKSKKEKKKEK--------VNNSNENPRKMCEQMRLKEK----------- 483
P K +K+EK +K+KK++ + ++ PR K K
Sbjct: 540 GPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSGGGSAA 599
Query: 484 -----------SKRNQPKKRKQQF-----IGLKSEDEDNAKPMNYDEKRQLSLNINKLPG 527
S PKK + G SE+E+ ++PM+YDEKRQLSL+INKLPG
Sbjct: 600 LGPSGFGPSGGSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPG 659
Query: 528 DKLGRVVHIIQSREPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPA--K 585
+KLGRVVHIIQ+REPSL +SNP+EIEIDFETLK STLRELE+YV +CLRK+P KP K
Sbjct: 660 EKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKPYTIKK 719
Query: 586 KIMMSKEELHSQKKQELEKRLLDVNNQLNSRKRQTK--SDKTQPSKAVE-NVSRLSESSS 642
+ +KEEL +KK+ELEKRL DV+ QLNS K+ K ++KT+ S A + VSRLS SSS
Sbjct: 720 PVGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKANEKTESSSAQQVAVSRLSASSS 779
Query: 643 SSSSSSESESSSSDLSSSDSSDSES 667
SS SSS S SS SSSD+SDS+S
Sbjct: 780 SSDSSSSSSSS----SSSDTSDSDS 800
Score = 31.2 bits (69), Expect = 4.8
Identities = 16/46 (34%), Positives = 23/46 (50%)
Query: 632 ENVSRLSESSSSSSSSSESESSSSDLSSSDSSDSESEMFPKFTEVK 677
E+ S S S SSS E + + S+SSDSE E + E++
Sbjct: 479 ESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQ 524
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 654 bits (1686), Expect = 0.0
Identities = 384/745 (51%), Positives = 488/745 (65%), Gaps = 94/745 (12%)
Query: 13 NPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKN 72
NPPPPE N KK GR+TNQLQYL KVV+K LWKH F+WPF++PVDAVKL LPDY+ IIK
Sbjct: 60 NPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQ 119
Query: 73 PMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQ 132
PMD+ TIK+RLEN YY ASEC++DFNTMF+NCY+YNKP DDIVLMAQ LEK+F+QK++
Sbjct: 120 PMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVAS 179
Query: 133 MPQEEQVVGV---KERIKKGTQQNI---AVSSAKEK---SSPSATEKVFKQQEIPSVF-- 181
MPQEEQ + V K KKG + +V+SA + SS S T EIP+
Sbjct: 180 MPQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAVSSVSHTALYTPPPEIPTTVLN 239
Query: 182 ---PKTSISPL-NVVQGASVNSSSQTAAQVT------KGVKRKADTTTPATSAVKA-SSE 230
P SPL + A + TAA KGVKRKADTTTP +A+ A S
Sbjct: 240 IPHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSP 299
Query: 231 FSP--TFTEKSVALPPIKENM------PKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKE 282
SP + K+ LPP++ P+ LPDSQQQ+ K K++EQL+HC+ ILKE
Sbjct: 300 ASPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKE 359
Query: 283 MLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVR 342
+L+KKH +YAWPFY PVD +ALGLH+Y+D++K+PMDL T+K KM+N++Y+DA +FAADVR
Sbjct: 360 LLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVR 419
Query: 343 LMFMNCYKYNPPDHEVVTMARMLQDVFETHFSKIPIEPVESMPLCY-------IKTDITE 395
LMF NCYKYNPPDH+VV MAR LQDVFE ++K+P EP+E PL + +E
Sbjct: 420 LMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSE 479
Query: 396 TTGRENTNEASSEG-------------NSSDDSEDERVKRLAKLQEQLKAVHQQLQVLSQ 442
++ E+++E+SSE + S DSE+ER RLA+LQEQL+AVH+QL LSQ
Sbjct: 480 SSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQ 539
Query: 443 VPFRKLNKKKEKSKKEKKKEK--------VNNSNENPRKMCEQMRLKEK----------- 483
P K +K+EK +K+KK++ + ++ PR K K
Sbjct: 540 GPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSGGGSAA 599
Query: 484 -----------SKRNQPKKRKQQF-----IGLKSEDEDNAKPMNYDEKRQLSLNINKLPG 527
S PKK + G SE+E+ ++PM+YDEKRQLSL+INKLPG
Sbjct: 600 LGPSGFGPSGGSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPG 659
Query: 528 DKLGRVVHIIQSREPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPA--K 585
+KLGRVVHIIQ+REPSL +SNP+EIEIDFETLK STLRELE+YV +CLRK+P KP K
Sbjct: 660 EKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKPYTIKK 719
Query: 586 KIMMSKEELHSQKKQELEKRLLDVNNQLNSRKRQTK--SDKTQPSKAVE-NVSRLSESSS 642
+ +KEEL +KK+ELEKRL DV+ QLNS K+ K ++KT+ S A + VSRLS SSS
Sbjct: 720 PVGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKANEKTESSSAQQVAVSRLSASSS 779
Query: 643 SSSSSSESESSSSDLSSSDSSDSES 667
SS SSS S SS SSSD+SDS+S
Sbjct: 780 SSDSSSSSSSS----SSSDTSDSDS 800
Score = 31.2 bits (69), Expect = 4.8
Identities = 16/46 (34%), Positives = 23/46 (50%)
Query: 632 ENVSRLSESSSSSSSSSESESSSSDLSSSDSSDSESEMFPKFTEVK 677
E+ S S S SSS E + + S+SSDSE E + E++
Sbjct: 479 ESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQ 524
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 647 bits (1668), Expect = 0.0
Identities = 371/716 (51%), Positives = 458/716 (63%), Gaps = 69/716 (9%)
Query: 12 VNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIK 71
VNPPPPE N K GR TNQLQY+Q VV+K LWKH F+WPF +PVDA+KL LPDY+ IIK
Sbjct: 19 VNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIK 78
Query: 72 NPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLS 131
NPMD+ TIKKRLEN YY ASEC++DFNTMF+NCY+YNKP DDIVLMAQALEK+F+QK++
Sbjct: 79 NPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVA 138
Query: 132 QMPQEEQVV---GVKERIKK--------GTQQNIAVSSAKEKSSPSATEKVFKQQEIPSV 180
QMPQEE + K + +K GTQQ AVSS + + Q + +
Sbjct: 139 QMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAA 198
Query: 181 FP----KTSISPLNVVQGASVNSSSQTAAQVT---------KGVKRKADTTTPATSAVKA 227
P +++ + V A+ + V KGVKRKADTTTP TSA+ A
Sbjct: 199 TPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITA 258
Query: 228 S-SEFSPTFTEKSVAL---------PPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCS 277
S SE P ++ A PIK PK L D + + K K++E LR+C
Sbjct: 259 SRSESPPPLSDPKQAKVVARRESGGRPIKP--PKKDLEDGEVPQHAGKKGKLSEHLRYCD 316
Query: 278 EILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKF 337
IL+EML+KKH +YAWPFY PVD AL LH+Y+D++K+PMDL T+K KMD +EY DA F
Sbjct: 317 SILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGF 376
Query: 338 AADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSKIPIEPVESMPL-CYIKTDITET 396
AADVRLMF NCYKYNPPDHEVV MAR LQDVFE F+K+P EPVE+ L +++
Sbjct: 377 AADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAAPMVSKG 436
Query: 397 TGRENTNEASSEGNSSDDSEDERVKRLAKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSK 456
++E SS + S DSE+ER RLA+LQEQLKAVH+QL LSQ P K KKKEK +
Sbjct: 437 AESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKE 496
Query: 457 KEKKKEKVNNSNENPRKMCEQMR-------LKEKSKRNQPKKR---------------KQ 494
KEKKK+ E + E+ + K+ ++ P K+ KQ
Sbjct: 497 KEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQ 556
Query: 495 QFIGLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPSLSNSNPDEIEI 554
SE+E+ PM+YDEKRQLSL+IN+LPG+KLGRVVHIIQSREPSL +SNPDEIEI
Sbjct: 557 ASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEI 616
Query: 555 DFETLKASTLRELEKYVSACLRKRPLKP----PAKKIMMSKEELHSQKKQELEKRLLDVN 610
DFETLK +TLRELE+YV +CL+K+ KP K+ SKEEL +KK+ELEKRL DV+
Sbjct: 617 DFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVS 676
Query: 611 NQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSESESSSSDLSSSDSSDSE 666
QL+S K+ + +K P A S SSSSSSES SSSS SSSDSSDSE
Sbjct: 677 GQLSSSKKPARKEK--PGSAPSG----GPSRLSSSSSSESGSSSSSGSSSDSSDSE 726
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 595 bits (1533), Expect = e-170
Identities = 360/763 (47%), Positives = 446/763 (58%), Gaps = 138/763 (18%)
Query: 4 PSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQL 63
P A NPPPPE N K R TNQLQYL +VVLK LWKH F+WPFQ+PVDAVKL L
Sbjct: 35 PQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNL 94
Query: 64 PDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALE 123
PDYY IIK PMD+ TIKKRLEN YY A ECI+DFNTMF+NCY+YNKPGDDIVLMA+ALE
Sbjct: 95 PDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALE 154
Query: 124 KLFMQKLSQMPQEEQVVGVKE-------RIKKGT-----------------------QQN 153
KLF+QK++++P EE + + + R + GT Q N
Sbjct: 155 KLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPN 214
Query: 154 IAVSSAKEKSSPSATEKVFKQQEIPSVFPKTSI----------------SPLNVVQGASV 197
A P+ T + Q + +V P + +P V +
Sbjct: 215 PPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPI 274
Query: 198 NSSSQTAAQVTKGVKRKADTTTPAT-SAVKASSEFSPT-----FTEKSVALPPIKENMPK 251
+++ + KGVKRKADTTTP T + P ++ + P+K PK
Sbjct: 275 IAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKP--PK 332
Query: 252 NVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYD 311
+PDSQQ K+ KV+EQL+ CS ILKEM AKKH +YAWPFY PVDV ALGLH+Y D
Sbjct: 333 KDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCD 392
Query: 312 VVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFET 371
++K+PMD+ TIK K++ +EY+DA +F ADVRLMF NCYKYNPPDHEVV MAR LQDVFE
Sbjct: 393 IIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM 452
Query: 372 HFSKIPIEPVE-----SMPLCYIKTD-ITETTGRENTNEASSEGNSS-DDSEDERVKRLA 424
F+K+P EP E S P T + + ++++++SS+ +SS DDSE+ER +RLA
Sbjct: 453 RFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLA 512
Query: 425 KLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRLKEKS 484
+LQEQLKAVH+QL LSQ P + KKKEK KKEKKKEK + RK + K K+
Sbjct: 513 ELQEQLKAVHEQLAALSQ-PQQNKPKKKEKDKKEKKKEK------HKRKEEVEENKKSKA 565
Query: 485 KRNQPKKRKQQFIG-------------------LKSEDEDNAKPMNYDEKRQLSLNINKL 525
K PKK K+ +SE+ED KPM+Y+EKRQLSL+INKL
Sbjct: 566 KEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKL 625
Query: 526 PGDKLGRVVHIIQSREPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAK 585
PG+KLGRVVHIIQSREPSL NSNPDEIEIDFETLK STLRELE+YV++CLRK+ KP A+
Sbjct: 626 PGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK-RKPQAE 684
Query: 586 KIMMSKEELHSQKKQELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSS 645
K+ DV ++ SS
Sbjct: 685 KV--------------------DV---------------------------IAGSSKMKG 697
Query: 646 SSSESESSSSDLSSSDSSDSESEMFPKFTEVKPNDSPSKENVK 688
SS SSS+ SSSDS DSE+EM PK K P +E K
Sbjct: 698 FSSSESESSSESSSSDSEDSETEMAPK---SKKKGHPGREQKK 737
Score = 104 bits (259), Expect = 4e-22
Identities = 68/190 (35%), Positives = 101/190 (53%), Gaps = 21/190 (11%)
Query: 777 PSGDSDTTMLESECQAPV--QKDIKIKNADSWKSLGK--PVKPSGVMKSSDELFNQFRKA 832
P G D + E + PV +KD+KIKN SW SL + P PS KSS + F QFR+A
Sbjct: 1171 PPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRA 1230
Query: 833 AIEKEVKARTQELIRKHLEQNTKELKASQENQRDLGNGLTV------ESFSNKIQNKCSG 886
A EKE + + + +H E+ + L+ + R+ + L E+ + Q +
Sbjct: 1231 AREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQR 1290
Query: 887 EEQKEHQQSSEA-----------QDKSKLWLLKDRDLARQKEQERRRREAMVGTIDMTLQ 935
+EQ++ QQ A + + L + R+LAR++EQERRRREAM TIDM Q
Sbjct: 1291 QEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQ 1350
Query: 936 SDIMTMFENN 945
SD++++FE N
Sbjct: 1351 SDLLSIFEEN 1360
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 586 bits (1510), Expect = e-167
Identities = 352/742 (47%), Positives = 437/742 (58%), Gaps = 135/742 (18%)
Query: 4 PSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQL 63
P A NPPPPE N K R TNQLQYL +VVLK LWKH F+WPFQ+PVDAVKL L
Sbjct: 35 PQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNL 94
Query: 64 PDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALE 123
PDYY IIK PMD+ TIKKRLEN YY A ECI+DFNTMF+NCY+YNKPGDDIVLMA+ALE
Sbjct: 95 PDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALE 154
Query: 124 KLFMQKLSQMPQEEQVVGVKE-------RIKKGT-----------------------QQN 153
KLF+QK++++P EE + + + R + GT Q N
Sbjct: 155 KLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPN 214
Query: 154 IAVSSAKEKSSPSATEKVFKQQEIPSVFPKTSI----------------SPLNVVQGASV 197
A P+ T + Q + +V P + +P V +
Sbjct: 215 PPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPI 274
Query: 198 NSSSQTAAQVTKGVKRKADTTTPAT-SAVKASSEFSPT-----FTEKSVALPPIKENMPK 251
+++ + KGVKRKADTTTP T + P ++ + P+K PK
Sbjct: 275 IAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKP--PK 332
Query: 252 NVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYD 311
+PDSQQ K+ KV+EQL+ CS ILKEM AKKH +YAWPFY PVDV ALGLH+Y D
Sbjct: 333 KDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCD 392
Query: 312 VVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFET 371
++K+PMD+ TIK K++ +EY+DA +F ADVRLMF NCYKYNPPDHEVV MAR LQDVFE
Sbjct: 393 IIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM 452
Query: 372 HFSKIPIEPVE-----SMPLCYIKTD-ITETTGRENTNEASSEGNSS-DDSEDERVKRLA 424
F+K+P EP E S P T + + ++++++SS+ +SS DDSE+ER +RLA
Sbjct: 453 RFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLA 512
Query: 425 KLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRLKEKS 484
+LQEQLKAVH+QL LSQ P + KKKEK KKEKKKEK + RK + K K+
Sbjct: 513 ELQEQLKAVHEQLAALSQ-PQQNKPKKKEKDKKEKKKEK------HKRKEEVEENKKSKA 565
Query: 485 KRNQPKKRKQQFIG-------------------LKSEDEDNAKPMNYDEKRQLSLNINKL 525
K PKK K+ +SE+ED KPM+Y+EKRQLSL+INKL
Sbjct: 566 KEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKL 625
Query: 526 PGDKLGRVVHIIQSREPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAK 585
PG+KLGRVVHIIQSREPSL NSNPDEIEIDFETLK STLRELE+YV++CLRK+ KP A+
Sbjct: 626 PGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK-RKPQAE 684
Query: 586 KIMMSKEELHSQKKQELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSS 645
K+ DV ++ SS
Sbjct: 685 KV--------------------DV---------------------------IAGSSKMKG 697
Query: 646 SSSESESSSSDLSSSDSSDSES 667
SS SSS+ SSSDS DSE+
Sbjct: 698 FSSSESESSSESSSSDSEDSET 719
>gi|93102371 polybromo 1 isoform 2 [Homo sapiens]
Length = 1582
Score = 93.6 bits (231), Expect = 8e-19
Identities = 77/311 (24%), Positives = 130/311 (41%), Gaps = 43/311 (13%)
Query: 60 KLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMA 119
K+Q PDYY IIK P+DL TI +R++N Y +D + + N YN+PG + A
Sbjct: 214 KVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDA 273
Query: 120 QALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQQEIPS 179
+++K+F K +++ E K ++ T N+A A + PS ++ ++ P+
Sbjct: 274 NSIKKIFYMKKAEIEHHEM---AKSSLRMRTPSNLA---AARLTGPSHSKGSLGEERNPT 327
Query: 180 VFPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSPTFTEKS 239
VQG +++ + + G + + D A + SE +
Sbjct: 328 ---SKYYRNKRAVQGGRLSAITMA---LQYGSESEEDAALAAARYEEGESEAESITSFMD 381
Query: 240 VALPPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPV 299
V+ P Q Y+ V R C +++A+ PFY+
Sbjct: 382 VSNP-------------FYQLYDTV---------RSCRNNQGQLIAE-------PFYHLP 412
Query: 300 DVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVV 359
+YY +K P+ L I+ K+ NQEY+ D+ LMF N +YN P+ +
Sbjct: 413 SKKK--YPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIY 470
Query: 360 TMARMLQDVFE 370
LQ V +
Sbjct: 471 KRVLKLQQVMQ 481
Score = 62.0 bits (149), Expect = 3e-09
Identities = 75/349 (21%), Positives = 129/349 (36%), Gaps = 47/349 (13%)
Query: 60 KLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMA 119
K + PDYY IK P+ L I+ +L+N+ Y D N MF N YN P I
Sbjct: 414 KKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRV 473
Query: 120 QALEKLFMQKLSQMPQEEQVVGVKERI----------KKGTQQNI----------AVSSA 159
L+++ K ++ + + + I K+ +++NI V A
Sbjct: 474 LKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEA 533
Query: 160 KEKSSPSATEKVFKQQEIPSVFP---KTSISP--LNVVQGASVNSSSQTAAQVTKGVK-- 212
+E S +F + +P K + P L +++ N + + +K
Sbjct: 534 REPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLM 593
Query: 213 -RKADTTTPATSAV------------KASSEFSPTFTEKSVALPPIKENMPKNVLPDSQQ 259
R A S V + E P + +A P +K + + P +
Sbjct: 594 FRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSK 653
Query: 260 QYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDL 319
++ ++L E +K K+ + F + L +YY +K PMD+
Sbjct: 654 YMTPMQ-----QKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELP--DYYLTIKKPMDM 706
Query: 320 GTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDV 368
I+ M +Y+D D +MF N YN P+ + A +L V
Sbjct: 707 EKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKV 755
Score = 53.1 bits (126), Expect = 1e-06
Identities = 26/76 (34%), Positives = 38/76 (50%)
Query: 62 QLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQA 121
+LPDYY IK PMD+ I+ + Y +EDF MF+N YN+P I A
Sbjct: 692 ELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALV 751
Query: 122 LEKLFMQKLSQMPQEE 137
L K+ ++ + +E
Sbjct: 752 LHKVLLETRRDLEGDE 767
Score = 51.2 bits (121), Expect = 4e-06
Identities = 67/330 (20%), Positives = 133/330 (40%), Gaps = 36/330 (10%)
Query: 308 NYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQD 367
+YY ++K P+DL TI +++ N YK + A D+ L+ N YN P +V A ++
Sbjct: 219 DYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKK 278
Query: 368 VFETHFSKIPIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDD----SEDERVKRL 423
+F + K IE E + T + S+G+ ++ S+ R KR
Sbjct: 279 IF--YMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKR- 335
Query: 424 AKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRLKEK 483
A +L A+ LQ S+ + E + E + + + +
Sbjct: 336 AVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRS 395
Query: 484 SKRNQPKKRKQQFIGLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPS 543
+ NQ + + F L S+ K +Y ++ ++ +++ + I+++ +
Sbjct: 396 CRNNQGQLIAEPFYHLPSK----KKYPDYYQQIKMPISLQQ------------IRTKLKN 439
Query: 544 LSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQELE 603
D +E D + + R ++ + KR LK +++ KK+EL
Sbjct: 440 QEYETLDHLECDLNLMFENAKR--YNVPNSAIYKRVLK---------LQQVMQAKKKELA 488
Query: 604 KR--LLDVNNQLNSRKRQTKSDKTQPSKAV 631
+R + D ++ ++S T S K + K +
Sbjct: 489 RRDDIEDGDSMISSATSDTGSAKRKSKKNI 518
Score = 47.4 bits (111), Expect = 6e-05
Identities = 23/62 (37%), Positives = 34/62 (54%)
Query: 308 NYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQD 367
+YY+VV P+DL I++K+ +EY D AD +L+F N Y PD A L D
Sbjct: 83 DYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWD 142
Query: 368 VF 369
++
Sbjct: 143 LY 144
Score = 44.3 bits (103), Expect = 5e-04
Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 4/111 (3%)
Query: 64 PDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALE 123
PDYY ++ P+DL I+++L+ + Y + DF +F+N Y KP A L
Sbjct: 82 PDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLW 141
Query: 124 KLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQ 174
L+++ ++ Q+ + E + Q N + E SSP+ +++ +Q
Sbjct: 142 DLYLRTRNEFVQKGE--ADDEDDDEDGQDN--QGTVTEGSSPAYLKEILEQ 188
Score = 43.5 bits (101), Expect = 0.001
Identities = 37/186 (19%), Positives = 74/186 (39%), Gaps = 3/186 (1%)
Query: 308 NYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQD 367
+YY ++ PMDL I+ + N +Y D++LMF N YN +V A +L+
Sbjct: 557 DYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEK 616
Query: 368 VFETHFSKI-PIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERVKRLAKL 426
+ + ++ P+ + M +K + + + ++ + K
Sbjct: 617 LLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKR 676
Query: 427 QEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQ--MRLKEKS 484
+L A+ +L S++P L KK ++ + + N ++ M E M
Sbjct: 677 GRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNAC 736
Query: 485 KRNQPK 490
N+P+
Sbjct: 737 TYNEPE 742
>gi|41281917 polybromo 1 isoform 4 [Homo sapiens]
Length = 1582
Score = 93.6 bits (231), Expect = 8e-19
Identities = 77/311 (24%), Positives = 130/311 (41%), Gaps = 43/311 (13%)
Query: 60 KLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMA 119
K+Q PDYY IIK P+DL TI +R++N Y +D + + N YN+PG + A
Sbjct: 214 KVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDA 273
Query: 120 QALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQQEIPS 179
+++K+F K +++ E K ++ T N+A A + PS ++ ++ P+
Sbjct: 274 NSIKKIFYMKKAEIEHHEM---AKSSLRMRTPSNLA---AARLTGPSHSKGSLGEERNPT 327
Query: 180 VFPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSPTFTEKS 239
VQG +++ + + G + + D A + SE +
Sbjct: 328 ---SKYYRNKRAVQGGRLSAITMA---LQYGSESEEDAALAAARYEEGESEAESITSFMD 381
Query: 240 VALPPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPV 299
V+ P Q Y+ V R C +++A+ PFY+
Sbjct: 382 VSNP-------------FYQLYDTV---------RSCRNNQGQLIAE-------PFYHLP 412
Query: 300 DVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVV 359
+YY +K P+ L I+ K+ NQEY+ D+ LMF N +YN P+ +
Sbjct: 413 SKKK--YPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIY 470
Query: 360 TMARMLQDVFE 370
LQ V +
Sbjct: 471 KRVLKLQQVMQ 481
Score = 62.0 bits (149), Expect = 3e-09
Identities = 75/349 (21%), Positives = 129/349 (36%), Gaps = 47/349 (13%)
Query: 60 KLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMA 119
K + PDYY IK P+ L I+ +L+N+ Y D N MF N YN P I
Sbjct: 414 KKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRV 473
Query: 120 QALEKLFMQKLSQMPQEEQVVGVKERI----------KKGTQQNI----------AVSSA 159
L+++ K ++ + + + I K+ +++NI V A
Sbjct: 474 LKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEA 533
Query: 160 KEKSSPSATEKVFKQQEIPSVFP---KTSISP--LNVVQGASVNSSSQTAAQVTKGVK-- 212
+E S +F + +P K + P L +++ N + + +K
Sbjct: 534 REPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLM 593
Query: 213 -RKADTTTPATSAV------------KASSEFSPTFTEKSVALPPIKENMPKNVLPDSQQ 259
R A S V + E P + +A P +K + + P +
Sbjct: 594 FRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSK 653
Query: 260 QYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDL 319
++ ++L E +K K+ + F + L +YY +K PMD+
Sbjct: 654 YMTPMQ-----QKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELP--DYYLTIKKPMDM 706
Query: 320 GTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDV 368
I+ M +Y+D D +MF N YN P+ + A +L V
Sbjct: 707 EKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKV 755
Score = 53.1 bits (126), Expect = 1e-06
Identities = 26/76 (34%), Positives = 38/76 (50%)
Query: 62 QLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQA 121
+LPDYY IK PMD+ I+ + Y +EDF MF+N YN+P I A
Sbjct: 692 ELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALV 751
Query: 122 LEKLFMQKLSQMPQEE 137
L K+ ++ + +E
Sbjct: 752 LHKVLLETRRDLEGDE 767
Score = 51.2 bits (121), Expect = 4e-06
Identities = 67/330 (20%), Positives = 133/330 (40%), Gaps = 36/330 (10%)
Query: 308 NYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQD 367
+YY ++K P+DL TI +++ N YK + A D+ L+ N YN P +V A ++
Sbjct: 219 DYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKK 278
Query: 368 VFETHFSKIPIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDD----SEDERVKRL 423
+F + K IE E + T + S+G+ ++ S+ R KR
Sbjct: 279 IF--YMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKR- 335
Query: 424 AKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRLKEK 483
A +L A+ LQ S+ + E + E + + + +
Sbjct: 336 AVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRS 395
Query: 484 SKRNQPKKRKQQFIGLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPS 543
+ NQ + + F L S+ K +Y ++ ++ +++ + I+++ +
Sbjct: 396 CRNNQGQLIAEPFYHLPSK----KKYPDYYQQIKMPISLQQ------------IRTKLKN 439
Query: 544 LSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQELE 603
D +E D + + R ++ + KR LK +++ KK+EL
Sbjct: 440 QEYETLDHLECDLNLMFENAKR--YNVPNSAIYKRVLK---------LQQVMQAKKKELA 488
Query: 604 KR--LLDVNNQLNSRKRQTKSDKTQPSKAV 631
+R + D ++ ++S T S K + K +
Sbjct: 489 RRDDIEDGDSMISSATSDTGSAKRKSKKNI 518
Score = 47.4 bits (111), Expect = 6e-05
Identities = 23/62 (37%), Positives = 34/62 (54%)
Query: 308 NYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQD 367
+YY+VV P+DL I++K+ +EY D AD +L+F N Y PD A L D
Sbjct: 83 DYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWD 142
Query: 368 VF 369
++
Sbjct: 143 LY 144
Score = 44.3 bits (103), Expect = 5e-04
Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 4/111 (3%)
Query: 64 PDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALE 123
PDYY ++ P+DL I+++L+ + Y + DF +F+N Y KP A L
Sbjct: 82 PDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLW 141
Query: 124 KLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQ 174
L+++ ++ Q+ + E + Q N + E SSP+ +++ +Q
Sbjct: 142 DLYLRTRNEFVQKGE--ADDEDDDEDGQDN--QGTVTEGSSPAYLKEILEQ 188
Score = 43.5 bits (101), Expect = 0.001
Identities = 37/186 (19%), Positives = 74/186 (39%), Gaps = 3/186 (1%)
Query: 308 NYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQD 367
+YY ++ PMDL I+ + N +Y D++LMF N YN +V A +L+
Sbjct: 557 DYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEK 616
Query: 368 VFETHFSKI-PIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERVKRLAKL 426
+ + ++ P+ + M +K + + + ++ + K
Sbjct: 617 LLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKR 676
Query: 427 QEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQ--MRLKEKS 484
+L A+ +L S++P L KK ++ + + N ++ M E M
Sbjct: 677 GRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNAC 736
Query: 485 KRNQPK 490
N+P+
Sbjct: 737 TYNEPE 742
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 84.0 bits (206), Expect = 6e-16
Identities = 40/94 (42%), Positives = 54/94 (57%), Gaps = 2/94 (2%)
Query: 37 KVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIE 96
K VL+ L H +WPF PVD PDYY +IK PMDL T+++R++ +YY K +E +
Sbjct: 2794 KRVLRSLQAHKMAWPFLEPVDPN--DAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVA 2851
Query: 97 DFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKL 130
D +F NC YN A+ LE F+QKL
Sbjct: 2852 DMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKL 2885
Score = 67.8 bits (164), Expect = 5e-11
Identities = 35/91 (38%), Positives = 51/91 (56%), Gaps = 5/91 (5%)
Query: 279 ILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFA 338
+L+ + A K AWPF PVD N +YY V+K PMDL T++E++ + Y+ +F
Sbjct: 2796 VLRSLQAHK---MAWPFLEPVDPN--DAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFV 2850
Query: 339 ADVRLMFMNCYKYNPPDHEVVTMARMLQDVF 369
AD+ +F NC YNP D A +L+ F
Sbjct: 2851 ADMTKIFDNCRYYNPSDSPFYQCAEVLESFF 2881
Score = 36.2 bits (82), Expect = 0.15
Identities = 75/341 (21%), Positives = 134/341 (39%), Gaps = 61/341 (17%)
Query: 387 CYIKTDITETTGRENTNEASSEGNSSDDSED-ERVKRLAKLQEQLKAVHQQLQVLSQVPF 445
C +K + RE+ +S + E+ E+VK+ K QE+ + + Q V P
Sbjct: 955 CAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPV 1014
Query: 446 RKLNKKKEKSKKEK----------KKEKV--------NNSNENPRKMCEQMR------LK 481
K K+K ++ + K V N+N N RK E + +
Sbjct: 1015 -KHQVWKQKGEEYRVTGYGGWSWISKTHVYRFVPKLPGNTNVNYRKSLEGTKNNMDENMD 1073
Query: 482 EKSKR---NQPKKRKQQFIGLKSE--DEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHI 536
E KR PKK K + K E D AK + +E ++I+K+ K V +
Sbjct: 1074 ESDKRKCSRSPKKIKIEPDSEKDEVKGSDAAKGADQNE-----MDISKITEKKDQDVKEL 1128
Query: 537 IQSREPSLSNSNPDEIEIDFETLKASTLRELEK----------YVSACLRKRPLKPPAKK 586
+ S P E++ D +T +E + ++ +K+
Sbjct: 1129 LDSDSDKPCKEEPMEVDDDMKTESHVNCQESSQVDVVNVSEGFHLRTSYKKKTKSSKLDG 1188
Query: 587 IMMSK-EELHSQKKQELEKRLLD------VNNQLNSRKRQTKSDK-TQPSKAVENVSRLS 638
++ + ++ ++KQ LEK L+ NS K ++S T+ + ++ S
Sbjct: 1189 LLERRIKQFTLEEKQRLEKIKLEGGIKGIGKTSTNSSKNLSESPVITKAKEGCQSDSMRQ 1248
Query: 639 ESSSSSSSSSE-------SESSSSDLSSSDSSDSESEMFPK 672
E S ++++ SES SS L SD S + ++++PK
Sbjct: 1249 EQSPNANNDQPEDLIQGCSESDSSVLRMSDPSHTTNKLYPK 1289
Score = 33.5 bits (75), Expect = 0.96
Identities = 72/307 (23%), Positives = 118/307 (38%), Gaps = 62/307 (20%)
Query: 446 RKLNKKKEKSKKEKKKEKVNNSN-ENPRKMCEQMRLKEKSKRNQPKKRKQQFIGLKSEDE 504
R +NK ++ K + +K NN N E+ +K + K N+PK I LK E
Sbjct: 1496 RPVNKCSDQIKLKNTTDKKNNENRESEKKGQRTSTFQINGKDNKPK------IYLKGE-- 1547
Query: 505 DNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPSLSNSNP--DEIEIDFETLKAS 562
E R +S N+ EP ++N N E +I T+K S
Sbjct: 1548 ---CLKEISESRVVSGNV------------------EPKVNNINKIIPENDIKSLTVKES 1586
Query: 563 TLREL--EKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQELEKRLLDVNNQLNSRKRQT 620
+R + +R K ++S + + LE L + +S + T
Sbjct: 1587 AIRPFINGDVIMEDFNERN-SSETKSHLLSSSDAEGNYRDSLE--TLPSTKESDSTQTTT 1643
Query: 621 KSDKTQPSKAVENVSRLSESSS------SSSSSSESESSSSD---------LSSSDSSDS 665
S S +V V + +S SS +SE ES+ S+ ++ +++ +
Sbjct: 1644 PSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNG 1703
Query: 666 ESEMFPKFTEVKPNDS----PSKENVKKMKNECILPEGRTGVTQIGYCVQDT-TSANTTL 720
ES+ TEV S SK +K K + +T V+ C + T T+ TT+
Sbjct: 1704 ESKRKTVITEVTTMTSTVATESKTVIKVEKG-----DKQTVVSSTENCAKSTVTTTTTTV 1758
Query: 721 VHQTTPS 727
+TPS
Sbjct: 1759 TKLSTPS 1765
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 84.0 bits (206), Expect = 6e-16
Identities = 40/94 (42%), Positives = 54/94 (57%), Gaps = 2/94 (2%)
Query: 37 KVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIE 96
K VL+ L H +WPF PVD PDYY +IK PMDL T+++R++ +YY K +E +
Sbjct: 2811 KRVLRSLQAHKMAWPFLEPVDPN--DAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVA 2868
Query: 97 DFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKL 130
D +F NC YN A+ LE F+QKL
Sbjct: 2869 DMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKL 2902
Score = 67.8 bits (164), Expect = 5e-11
Identities = 35/91 (38%), Positives = 51/91 (56%), Gaps = 5/91 (5%)
Query: 279 ILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFA 338
+L+ + A K AWPF PVD N +YY V+K PMDL T++E++ + Y+ +F
Sbjct: 2813 VLRSLQAHK---MAWPFLEPVDPN--DAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFV 2867
Query: 339 ADVRLMFMNCYKYNPPDHEVVTMARMLQDVF 369
AD+ +F NC YNP D A +L+ F
Sbjct: 2868 ADMTKIFDNCRYYNPSDSPFYQCAEVLESFF 2898
Score = 36.2 bits (82), Expect = 0.15
Identities = 75/341 (21%), Positives = 134/341 (39%), Gaps = 61/341 (17%)
Query: 387 CYIKTDITETTGRENTNEASSEGNSSDDSED-ERVKRLAKLQEQLKAVHQQLQVLSQVPF 445
C +K + RE+ +S + E+ E+VK+ K QE+ + + Q V P
Sbjct: 829 CAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPV 888
Query: 446 RKLNKKKEKSKKEK----------KKEKV--------NNSNENPRKMCEQMR------LK 481
K K+K ++ + K V N+N N RK E + +
Sbjct: 889 -KHQVWKQKGEEYRVTGYGGWSWISKTHVYRFVPKLPGNTNVNYRKSLEGTKNNMDENMD 947
Query: 482 EKSKR---NQPKKRKQQFIGLKSE--DEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHI 536
E KR PKK K + K E D AK + +E ++I+K+ K V +
Sbjct: 948 ESDKRKCSRSPKKIKIEPDSEKDEVKGSDAAKGADQNE-----MDISKITEKKDQDVKEL 1002
Query: 537 IQSREPSLSNSNPDEIEIDFETLKASTLRELEK----------YVSACLRKRPLKPPAKK 586
+ S P E++ D +T +E + ++ +K+
Sbjct: 1003 LDSDSDKPCKEEPMEVDDDMKTESHVNCQESSQVDVVNVSEGFHLRTSYKKKTKSSKLDG 1062
Query: 587 IMMSK-EELHSQKKQELEKRLLD------VNNQLNSRKRQTKSDK-TQPSKAVENVSRLS 638
++ + ++ ++KQ LEK L+ NS K ++S T+ + ++ S
Sbjct: 1063 LLERRIKQFTLEEKQRLEKIKLEGGIKGIGKTSTNSSKNLSESPVITKAKEGCQSDSMRQ 1122
Query: 639 ESSSSSSSSSE-------SESSSSDLSSSDSSDSESEMFPK 672
E S ++++ SES SS L SD S + ++++PK
Sbjct: 1123 EQSPNANNDQPEDLIQGCSESDSSVLRMSDPSHTTNKLYPK 1163
Score = 33.5 bits (75), Expect = 0.96
Identities = 72/307 (23%), Positives = 118/307 (38%), Gaps = 62/307 (20%)
Query: 446 RKLNKKKEKSKKEKKKEKVNNSN-ENPRKMCEQMRLKEKSKRNQPKKRKQQFIGLKSEDE 504
R +NK ++ K + +K NN N E+ +K + K N+PK I LK E
Sbjct: 1370 RPVNKCSDQIKLKNTTDKKNNENRESEKKGQRTSTFQINGKDNKPK------IYLKGE-- 1421
Query: 505 DNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPSLSNSNP--DEIEIDFETLKAS 562
E R +S N+ EP ++N N E +I T+K S
Sbjct: 1422 ---CLKEISESRVVSGNV------------------EPKVNNINKIIPENDIKSLTVKES 1460
Query: 563 TLREL--EKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQELEKRLLDVNNQLNSRKRQT 620
+R + +R K ++S + + LE L + +S + T
Sbjct: 1461 AIRPFINGDVIMEDFNERN-SSETKSHLLSSSDAEGNYRDSLE--TLPSTKESDSTQTTT 1517
Query: 621 KSDKTQPSKAVENVSRLSESSS------SSSSSSESESSSSD---------LSSSDSSDS 665
S S +V V + +S SS +SE ES+ S+ ++ +++ +
Sbjct: 1518 PSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNG 1577
Query: 666 ESEMFPKFTEVKPNDS----PSKENVKKMKNECILPEGRTGVTQIGYCVQDT-TSANTTL 720
ES+ TEV S SK +K K + +T V+ C + T T+ TT+
Sbjct: 1578 ESKRKTVITEVTTMTSTVATESKTVIKVEKG-----DKQTVVSSTENCAKSTVTTTTTTV 1632
Query: 721 VHQTTPS 727
+TPS
Sbjct: 1633 TKLSTPS 1639
>gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]
Length = 832
Score = 79.7 bits (195), Expect = 1e-14
Identities = 39/109 (35%), Positives = 58/109 (53%), Gaps = 2/109 (1%)
Query: 24 KNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRL 83
K R +QL K +L+ + H +WPF PV + + P YY +I+ PMDL T+ +RL
Sbjct: 720 KEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVK--RTEAPGYYEVIRFPMDLKTMSERL 777
Query: 84 ENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQ 132
+N+YY + D +F+NC YN P + A LEK F K+ +
Sbjct: 778 KNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
Score = 68.6 bits (166), Expect = 3e-11
Identities = 41/99 (41%), Positives = 57/99 (57%), Gaps = 8/99 (8%)
Query: 280 LKEMLAK-KHFSYAWPFYNPVD-VNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKF 337
LK +L + K AWPF PV A G YY+V++ PMDL T+ E++ N+ Y F
Sbjct: 732 LKSILQQVKSHQSAWPFMEPVKRTEAPG---YYEVIRFPMDLKTMSERLKNRYYVSKKLF 788
Query: 338 AADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSKI 376
AD++ +F NC +YNPP+ E A +L+ F FSKI
Sbjct: 789 MADLQRVFTNCKEYNPPESEYYKCANILEKFF---FSKI 824
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 77.0 bits (188), Expect = 8e-14
Identities = 73/279 (26%), Positives = 114/279 (40%), Gaps = 28/279 (10%)
Query: 131 SQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQQEI-----PSVFPKTS 185
+Q+PQ+ Q QQ + S P+ T + Q P+V +
Sbjct: 891 TQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQ 950
Query: 186 ISPLNVVQGASVNSSSQTAAQVTKGVKRKA----------DTTTPATSAVKA------SS 229
+S VNS + Q ++ VK +A DT S K S+
Sbjct: 951 VSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMEST 1010
Query: 230 EFSPTFTEKSVALPPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHF 289
E TE + ++ + S K + E+LR E L ++
Sbjct: 1011 ETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQD- 1069
Query: 290 SYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCY 349
+ PF PVD LG+ +Y+D+VK+PMDL TIK K+D +Y++ +++ D+ LMF N +
Sbjct: 1070 PESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAW 1129
Query: 350 KYNPPDHEVVTMARMLQDVFETHFSKIPIEPV-ESMPLC 387
YN V L +VFE I+PV +S+ C
Sbjct: 1130 LYNRKTSRVYKYCSKLSEVFEQE-----IDPVMQSLGYC 1163
Score = 71.6 bits (174), Expect = 3e-12
Identities = 32/87 (36%), Positives = 55/87 (63%)
Query: 49 SWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLY 108
S PF++PVD L +PDY+ I+K+PMDL+TIK++L+ Y + + ++D MF+N +LY
Sbjct: 1072 SLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLY 1131
Query: 109 NKPGDDIVLMAQALEKLFMQKLSQMPQ 135
N+ + L ++F Q++ + Q
Sbjct: 1132 NRKTSRVYKYCSKLSEVFEQEIDPVMQ 1158
Score = 30.4 bits (67), Expect = 8.2
Identities = 26/113 (23%), Positives = 43/113 (38%), Gaps = 3/113 (2%)
Query: 579 PLKPPAKKIMMSKEELHSQKKQELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLS 638
PL PA I S E+ + + K + K + QP A +S
Sbjct: 939 PLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDIS 998
Query: 639 ES--SSSSSSSSESESSSSDLSSSDSSDSESEMFPKFTEVKPNDSPSKENVKK 689
ES S+E+E S++L ++ + E + T+ P SK+ + K
Sbjct: 999 ESKVEDCKMESTETEERSTEL-KTEIKEEEDQPSTSATQSSPAPGQSKKKIFK 1050
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 77.0 bits (188), Expect = 8e-14
Identities = 40/95 (42%), Positives = 56/95 (58%), Gaps = 6/95 (6%)
Query: 294 PFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNP 353
PF PVD LG+ +Y+D+VKNPMDL TIK K+D +Y++ +++ DV LMF N + YN
Sbjct: 1072 PFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNR 1131
Query: 354 PDHEVVTMARMLQDVFETHFSKIPIEPV-ESMPLC 387
V L +VFE I+PV +S+ C
Sbjct: 1132 KTSRVYKFCSKLAEVFEQE-----IDPVMQSLGYC 1161
Score = 73.2 bits (178), Expect = 1e-12
Identities = 33/87 (37%), Positives = 55/87 (63%)
Query: 49 SWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLY 108
S PF++PVD L +PDY+ I+KNPMDL+TIK++L+ Y + + ++D MF+N +LY
Sbjct: 1070 SLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLY 1129
Query: 109 NKPGDDIVLMAQALEKLFMQKLSQMPQ 135
N+ + L ++F Q++ + Q
Sbjct: 1130 NRKTSRVYKFCSKLAEVFEQEIDPVMQ 1156
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 77.0 bits (188), Expect = 8e-14
Identities = 40/95 (42%), Positives = 56/95 (58%), Gaps = 6/95 (6%)
Query: 294 PFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNP 353
PF PVD LG+ +Y+D+VKNPMDL TIK K+D +Y++ +++ DV LMF N + YN
Sbjct: 1110 PFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNR 1169
Query: 354 PDHEVVTMARMLQDVFETHFSKIPIEPV-ESMPLC 387
V L +VFE I+PV +S+ C
Sbjct: 1170 KTSRVYKFCSKLAEVFEQE-----IDPVMQSLGYC 1199
Score = 73.2 bits (178), Expect = 1e-12
Identities = 33/87 (37%), Positives = 55/87 (63%)
Query: 49 SWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLY 108
S PF++PVD L +PDY+ I+KNPMDL+TIK++L+ Y + + ++D MF+N +LY
Sbjct: 1108 SLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLY 1167
Query: 109 NKPGDDIVLMAQALEKLFMQKLSQMPQ 135
N+ + L ++F Q++ + Q
Sbjct: 1168 NRKTSRVYKFCSKLAEVFEQEIDPVMQ 1194
>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
[Homo sapiens]
Length = 1050
Score = 77.0 bits (188), Expect = 8e-14
Identities = 41/98 (41%), Positives = 57/98 (58%), Gaps = 5/98 (5%)
Query: 43 LWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKY--YAKASECIEDFNT 100
L+ H S FQ PV L +PDYY IIKNPMDL+TIKKRL+ Y Y+K + + DF
Sbjct: 915 LYCHEMSLAFQDPVP---LTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRL 971
Query: 101 MFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQ 138
+F NC +N+P ++ LE F + L + E++
Sbjct: 972 IFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYPEKR 1009
Score = 69.3 bits (168), Expect = 2e-11
Identities = 44/137 (32%), Positives = 66/137 (48%), Gaps = 16/137 (11%)
Query: 295 FYNPVDVNALGLHNYYDVVKNPMDLGTIKEKM--DNQEYKDAYKFAADVRLMFMNCYKYN 352
F +PV L + +YY ++KNPMDL TIK+++ D Y F AD RL+F NC ++N
Sbjct: 924 FQDPVP---LTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFN 980
Query: 353 PPDHEVVTMARMLQDVFETHFSKIPIEPVESMPLCYIKTDITETTGRENTNEASSEGNSS 412
PD EV L++ FE E + Y + + R + + +S
Sbjct: 981 EPDSEVANAGIKLENYFE-----------ELLKNLYPEKRFPKPEFRNESEDNKFSDDSD 1029
Query: 413 DDSEDERVKRLAKLQEQ 429
DD R KRL ++E+
Sbjct: 1030 DDFVQPRKKRLKSIEER 1046
>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
[Homo sapiens]
Length = 1016
Score = 77.0 bits (188), Expect = 8e-14
Identities = 41/98 (41%), Positives = 57/98 (58%), Gaps = 5/98 (5%)
Query: 43 LWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKY--YAKASECIEDFNT 100
L+ H S FQ PV L +PDYY IIKNPMDL+TIKKRL+ Y Y+K + + DF
Sbjct: 881 LYCHEMSLAFQDPVP---LTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRL 937
Query: 101 MFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQ 138
+F NC +N+P ++ LE F + L + E++
Sbjct: 938 IFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYPEKR 975
Score = 69.3 bits (168), Expect = 2e-11
Identities = 44/137 (32%), Positives = 66/137 (48%), Gaps = 16/137 (11%)
Query: 295 FYNPVDVNALGLHNYYDVVKNPMDLGTIKEKM--DNQEYKDAYKFAADVRLMFMNCYKYN 352
F +PV L + +YY ++KNPMDL TIK+++ D Y F AD RL+F NC ++N
Sbjct: 890 FQDPVP---LTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFN 946
Query: 353 PPDHEVVTMARMLQDVFETHFSKIPIEPVESMPLCYIKTDITETTGRENTNEASSEGNSS 412
PD EV L++ FE E + Y + + R + + +S
Sbjct: 947 EPDSEVANAGIKLENYFE-----------ELLKNLYPEKRFPKPEFRNESEDNKFSDDSD 995
Query: 413 DDSEDERVKRLAKLQEQ 429
DD R KRL ++E+
Sbjct: 996 DDFVQPRKKRLKSIEER 1012
>gi|153791535 general control of amino acid synthesis 5-like 2 [Homo
sapiens]
Length = 837
Score = 75.5 bits (184), Expect = 2e-13
Identities = 38/103 (36%), Positives = 55/103 (53%), Gaps = 2/103 (1%)
Query: 30 NQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYA 89
+QL K +L + H +WPF PV K + PDYY +I+ P+DL T+ +RL ++YY
Sbjct: 731 DQLYTTLKNLLAQIKSHPSAWPFMEPVK--KSEAPDYYEVIRFPIDLKTMTERLRSRYYV 788
Query: 90 KASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQ 132
+ D + +NC YN P + A ALEK F KL +
Sbjct: 789 TRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831
Score = 63.2 bits (152), Expect = 1e-09
Identities = 34/91 (37%), Positives = 52/91 (57%), Gaps = 3/91 (3%)
Query: 280 LKEMLAK-KHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFA 338
LK +LA+ K AWPF PV + +YY+V++ P+DL T+ E++ ++ Y F
Sbjct: 737 LKNLLAQIKSHPSAWPFMEPVKKSEAP--DYYEVIRFPIDLKTMTERLRSRYYVTRKLFV 794
Query: 339 ADVRLMFMNCYKYNPPDHEVVTMARMLQDVF 369
AD++ + NC +YNPPD E A L+ F
Sbjct: 795 ADLQRVIANCREYNPPDSEYCRCASALEKFF 825
>gi|148612882 cat eye syndrome chromosome region, candidate 2 [Homo
sapiens]
Length = 1484
Score = 73.6 bits (179), Expect = 8e-13
Identities = 45/125 (36%), Positives = 63/125 (50%), Gaps = 5/125 (4%)
Query: 3 LPSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWK-HSFSWPFQRPVDAVKL 61
LP + + N P E TK L + + KV+ D+ K H SWPF PVD +
Sbjct: 411 LPPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVL--DVVKAHKDSWPFLEPVD--ES 466
Query: 62 QLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQA 121
P+YY IIK PMD+++++K+L Y E + D TMF NC YN + M+
Sbjct: 467 YAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDN 526
Query: 122 LEKLF 126
LE+ F
Sbjct: 527 LERCF 531
Score = 59.7 bits (143), Expect = 1e-08
Identities = 29/84 (34%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Query: 292 AWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKY 351
+WPF PVD + NYY ++K PMD+ ++++K++ Y +F D++ MF NC KY
Sbjct: 456 SWPFLEPVDESYAP--NYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKY 513
Query: 352 NPPDHEVVTMARMLQDVFETHFSK 375
N E M+ L+ F K
Sbjct: 514 NGESSEYTKMSDNLERCFHRAMMK 537
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b
[Homo sapiens]
Length = 1524
Score = 73.2 bits (178), Expect = 1e-12
Identities = 39/97 (40%), Positives = 60/97 (61%), Gaps = 5/97 (5%)
Query: 15 PPPEYINTKKNGRL--TNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKN 72
P P + + +GR ++L +++V+ +L +H SWPF + V K+Q+PDYY IIK
Sbjct: 1384 PSPVTLGRRSSGRQGGVHELSAFEQLVV-ELVRHDDSWPFLKLVS--KIQVPDYYDIIKK 1440
Query: 73 PMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYN 109
P+ LN I++++ Y ASE I+D MFSNC+ YN
Sbjct: 1441 PIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYN 1477
Score = 64.7 bits (156), Expect = 4e-10
Identities = 32/92 (34%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query: 292 AWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKY 351
+WPF V + + + +YYD++K P+ L I+EK++ EYK A +F D+ LMF NC++Y
Sbjct: 1419 SWPFLKLV--SKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEY 1476
Query: 352 NPPDHEVVTMARMLQDVFETHFSKIPIEPVES 383
NP + LQ F K+ + S
Sbjct: 1477 NPRNTSEAKAGTRLQAFFHIQAQKLGLHVTPS 1508
Score = 35.8 bits (81), Expect = 0.19
Identities = 27/124 (21%), Positives = 63/124 (50%), Gaps = 5/124 (4%)
Query: 400 ENTNEASSEGNSSDDSEDERVKRLAKLQEQLKAVHQQLQVLSQVPFRKLN-KKKEKSKKE 458
+ N A+ + +S S+ + + QE++K++ + L + L KKKEK KE
Sbjct: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
Query: 459 KKKEKVNNSNENPR----KMCEQMRLKEKSKRNQPKKRKQQFIGLKSEDEDNAKPMNYDE 514
KK+E++ E R + E+++++ + +R + ++ K++++ + + M D+
Sbjct: 347 KKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECDD 406
Query: 515 KRQL 518
++L
Sbjct: 407 LKEL 410
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform a
[Homo sapiens]
Length = 1556
Score = 73.2 bits (178), Expect = 1e-12
Identities = 39/97 (40%), Positives = 60/97 (61%), Gaps = 5/97 (5%)
Query: 15 PPPEYINTKKNGRL--TNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKN 72
P P + + +GR ++L +++V+ +L +H SWPF + V K+Q+PDYY IIK
Sbjct: 1416 PSPVTLGRRSSGRQGGVHELSAFEQLVV-ELVRHDDSWPFLKLVS--KIQVPDYYDIIKK 1472
Query: 73 PMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYN 109
P+ LN I++++ Y ASE I+D MFSNC+ YN
Sbjct: 1473 PIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYN 1509
Score = 64.7 bits (156), Expect = 4e-10
Identities = 32/92 (34%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query: 292 AWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKY 351
+WPF V + + + +YYD++K P+ L I+EK++ EYK A +F D+ LMF NC++Y
Sbjct: 1451 SWPFLKLV--SKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEY 1508
Query: 352 NPPDHEVVTMARMLQDVFETHFSKIPIEPVES 383
NP + LQ F K+ + S
Sbjct: 1509 NPRNTSEAKAGTRLQAFFHIQAQKLGLHVTPS 1540
Score = 35.8 bits (81), Expect = 0.19
Identities = 27/124 (21%), Positives = 63/124 (50%), Gaps = 5/124 (4%)
Query: 400 ENTNEASSEGNSSDDSEDERVKRLAKLQEQLKAVHQQLQVLSQVPFRKLN-KKKEKSKKE 458
+ N A+ + +S S+ + + QE++K++ + L + L KKKEK KE
Sbjct: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
Query: 459 KKKEKVNNSNENPR----KMCEQMRLKEKSKRNQPKKRKQQFIGLKSEDEDNAKPMNYDE 514
KK+E++ E R + E+++++ + +R + ++ K++++ + + M D+
Sbjct: 347 KKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECDD 406
Query: 515 KRQL 518
++L
Sbjct: 407 LKEL 410
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 72.8 bits (177), Expect = 1e-12
Identities = 55/199 (27%), Positives = 91/199 (45%), Gaps = 22/199 (11%)
Query: 178 PSVFPKTSISPLNV----VQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSP 233
P+ K S L + V+G N S + G D+ + ++S + + +
Sbjct: 1976 PACIAKASGQTLKIKKLHVKGKKTNESKKGKKVTLTGDTEDEDSASTSSSLKRGNKDLKK 2035
Query: 234 TFTEKSVALPPIKENMPKNVLPDSQQQYNVVKTVKV--TEQLRHCSEILKEMLAKKHFSY 291
E++ ++ N+ K Q+ + VK K ++ L CS IL EM +
Sbjct: 2036 RKMEENTSI-----NLSK------QESFTSVKKPKRDDSKDLALCSMILTEMETHED--- 2081
Query: 292 AWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKY 351
AWPF PV++ + Y V+K PMD TI+EK+ + +Y + FA DVRL+F NC +
Sbjct: 2082 AWPFLLPVNLKLVP--GYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETF 2139
Query: 352 NPPDHEVVTMARMLQDVFE 370
N D ++ ++ FE
Sbjct: 2140 NEDDSDIGRAGHNMRKYFE 2158
Score = 58.5 bits (140), Expect = 3e-08
Identities = 34/111 (30%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Query: 19 YINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNT 78
+ + KK R ++ L ++L ++ H +WPF PV+ +KL +P Y +IK PMD +T
Sbjct: 2052 FTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVN-LKL-VPGYKKVIKKPMDFST 2109
Query: 79 IKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQK 129
I+++L + Y D +F NC +N+ DI + K F +K
Sbjct: 2110 IREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKK 2160
Score = 43.9 bits (102), Expect = 7e-04
Identities = 38/120 (31%), Positives = 55/120 (45%), Gaps = 11/120 (9%)
Query: 610 NNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSESESSSSDLSSSDSSD---SE 666
N L++R + K DK KA+E S S+S S S + S++SS +SSSDS D E
Sbjct: 219 NQPLDARVDKIK-DKKPRKKAME-----SSSNSDSDSGTSSDTSSEGISSSDSDDLEEDE 272
Query: 667 SEMFPKFTEVKPNDSPSKENVKKMKNECILPEGRTGVTQIGYCVQDTTSANTTLVHQTTP 726
E E + +DS S+ + N +L G + G + T A +HQ P
Sbjct: 273 EEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQ--KATEKAQEKRIHQPLP 330
Score = 37.0 bits (84), Expect = 0.087
Identities = 55/245 (22%), Positives = 97/245 (39%), Gaps = 36/245 (14%)
Query: 598 KKQELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSS-----SSESES 652
K Q L+ R+ + ++ RK+ +S S + + SE SSS S E E
Sbjct: 218 KNQPLDARVDKIKDK-KPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEED 276
Query: 653 SSSDLSSSDSSDSESEMFPK---------FTEVKPNDSPSKENVKKMKNECILP---EGR 700
S + S D SDSESE K ++ K + + E ++ + LP E +
Sbjct: 277 QSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIHQPLPLASESQ 336
Query: 701 TGVTQIGYCVQDTTSANTTLVHQTTPSHVMPPNHHQ-------LAFNYQELEHLQTVKNI 753
T Q S + Q++ + N H L N + L + K
Sbjct: 337 THSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKE 396
Query: 754 SPLQILPPSGDSEQLSNGITVMHPSGDSDTTMLESECQAPVQK-----DIKIKNADSWKS 808
+ ++++ PS D + N T ++++L SE ++ ++ ++K +S KS
Sbjct: 397 TYMKLIVPSPDVLKAGNKNT------SEESSLLTSELRSKREQYKQAFPSQLKKQESSKS 450
Query: 809 LGKPV 813
L K +
Sbjct: 451 LKKVI 455
Score = 35.4 bits (80), Expect = 0.25
Identities = 33/112 (29%), Positives = 58/112 (51%), Gaps = 25/112 (22%)
Query: 425 KLQEQLKAVHQQLQV--LSQVPFRK-LNKKKEKSKKEKKKEKVNNSNENPRKMCE-QMRL 480
K +EQ+K + QQ ++ + Q+ K L ++ K+KKKE+ N+ K+ E + R+
Sbjct: 933 KQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANA-----KLLEAEKRI 987
Query: 481 KEKSKR--------NQPKKRKQQFIGL--------KSEDEDNAKPMNYDEKR 516
KEK R +Q ++R++Q + L K+E+++ K DEKR
Sbjct: 988 KEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKR 1039
Score = 35.0 bits (79), Expect = 0.33
Identities = 71/329 (21%), Positives = 127/329 (38%), Gaps = 48/329 (14%)
Query: 382 ESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERVKRLAKLQEQLKAVHQQLQVLS 441
+ +P + + E + ++T+ S G S+ VK L+ + + K + +L V S
Sbjct: 352 QQLPFIFQSSQAKEESVNKHTSVIQSTGLVSN------VKPLSLVNQAKKETYMKLIVPS 405
Query: 442 QVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRLKEKSKRNQPKKRKQQFIGLKS 501
+ NK + E + + + Q++ +E SK K+ L +
Sbjct: 406 PDVLKAGNKNTSEESSLLTSELRSKREQYKQAFPSQLKKQESSK-----SLKKVIAALSN 460
Query: 502 EDEDNAKPMNYDEKRQLSLN------INKLPGDKL--GRVVHIIQSREPSLSNSNPDEIE 553
++ P + K+ L N N L G+ G + +IQ +L+ + +
Sbjct: 461 PKATSSSPAH--PKQTLENNHPNPFLTNALLGNHQPNGVIQSVIQEAPLALTTKTKMQSK 518
Query: 554 IDFETLKASTLRELEKYVSACLRKRPLKPPAKKIMMSKEE-LHSQKKQELEKRLLDVNNQ 612
I+ E + A++ V+ R +M S LHSQ K++ V+N
Sbjct: 519 IN-ENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMPSASPILHSQGKEKA------VSNN 571
Query: 613 LNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSES-------------ESSSSDLSS 659
+N K Q S P+K++ R ++S SS SE E D S
Sbjct: 572 VNPVKTQHHS---HPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDES 628
Query: 660 SDS---SDSESEMFPKFTEVKPNDSPSKE 685
DS SDS SE + +E + +D ++
Sbjct: 629 DDSQSESDSNSESDTEGSEEEDDDDKDQD 657
Score = 33.5 bits (75), Expect = 0.96
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 9/93 (9%)
Query: 424 AKLQEQLKAVHQQLQVLSQVPFRKLNKKKE-KSKKEKKKEKVNNSNENPRKMCEQ---MR 479
AKL +L+A Q RKL K+++ + KE KK++ + E RK EQ M+
Sbjct: 883 AKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMK 942
Query: 480 LKEKSKRNQ-----PKKRKQQFIGLKSEDEDNA 507
+EK KR Q + R QQ + K + ++ A
Sbjct: 943 QQEKIKRIQQIRMEKELRAQQILEAKKKKKEEA 975
>gi|34996489 pleckstrin homology domain interacting protein [Homo
sapiens]
Length = 1821
Score = 67.0 bits (162), Expect = 8e-11
Identities = 52/183 (28%), Positives = 83/183 (45%), Gaps = 16/183 (8%)
Query: 246 KENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALG 305
K++ P+ L + Q Y++ K C E+L + + PF PVD+ L
Sbjct: 1301 KDHQPRRRLRNRAQSYDIQAWKK------QCEELLNLIFQCEDSE---PFRQPVDL--LE 1349
Query: 306 LHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDH-EVVTMARM 364
+Y D++ PMD T++E ++ Y+ + DVRL+F N Y P + +M+
Sbjct: 1350 YPDYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYTPSKRSRIYSMSLR 1409
Query: 365 LQDVFETHFSKIPIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERVKRLA 424
L FE H S + + +S + + IT+ R SS +SS S ER KR+
Sbjct: 1410 LSAFFEEHISSV-LSDYKSALRFHKRNTITK---RRKKRNRSSSVSSSAASSPERKKRIL 1465
Query: 425 KLQ 427
K Q
Sbjct: 1466 KPQ 1468
Score = 57.4 bits (137), Expect = 6e-08
Identities = 56/208 (26%), Positives = 91/208 (43%), Gaps = 24/208 (11%)
Query: 49 SWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLY 108
S PF++PVD L+ PDY II PMD T+++ LE Y E +D +FSN Y
Sbjct: 1338 SEPFRQPVDL--LEYPDYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAY 1395
Query: 109 N-KPGDDIVLMAQALEKLFMQKLSQMPQE--------EQVVGVKERIKKGTQQNIAVSSA 159
I M+ L F + +S + + ++ K R K+ +++ S+A
Sbjct: 1396 TPSKRSRIYSMSLRLSAFFEEHISSVLSDYKSALRFHKRNTITKRRKKRNRSSSVSSSAA 1455
Query: 160 KEKSSPSATEKVFKQQ----EIPSVF--PKTSISPLNVVQGASVNSSSQTAAQVTKGVKR 213
SSP +++ K Q S F P SI P + A +N +++++ V R
Sbjct: 1456 ---SSPERKKRILKPQLKSESSTSAFSTPTRSIPPRH--NAAQINGKTESSSVVRTRSNR 1510
Query: 214 KADTTTPATSAVKASSEFSPTFTEKSVA 241
P + ++S + TF K+ A
Sbjct: 1511 V--VVDPVVTEQPSTSSAAKTFITKANA 1536
Score = 54.7 bits (130), Expect = 4e-07
Identities = 141/660 (21%), Positives = 248/660 (37%), Gaps = 79/660 (11%)
Query: 276 CSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAY 335
C I+ + A F PVD+ A + Y VV P DL TIK++++N+ Y+
Sbjct: 1165 CERIVAGINQLMTLDIASAFVAPVDLQAYPM--YCTVVAYPTDLSTIKQRLENRFYRRVS 1222
Query: 336 KFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSKIPIEPVESMPLCYIKTDITE 395
+VR + N +N P +V A+ + D+ HF K +PL
Sbjct: 1223 SLMWEVRYIEHNTRTFNEPGSPIVKSAKFVTDLL-LHFIK-DQTCYNIIPLYNSMKKKVL 1280
Query: 396 TTGRENTNEASSEGNSSDDSEDERVKRLAK-------LQEQLKAVHQQLQVLSQV----P 444
+ + +A G S+ +D + +R + +Q K + L ++ Q P
Sbjct: 1281 SDSEDEEKDADVPGTSTRKRKDHQPRRRLRNRAQSYDIQAWKKQCEELLNLIFQCEDSEP 1340
Query: 445 FRK-------------LNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRL-KEKSKRNQPK 490
FR+ ++ + + + E N E+P ++C+ +RL SK P
Sbjct: 1341 FRQPVDLLEYPDYRDIIDTPMDFATVRETLEAGN--YESPMELCKDVRLIFSNSKAYTPS 1398
Query: 491 KRKQQF---IGLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPSLSNS 547
KR + + + L + E++ + D K L + + + ++R S+S+S
Sbjct: 1399 KRSRIYSMSLRLSAFFEEHISSVLSDYKSALRFHKRNTITKRRKK-----RNRSSSVSSS 1453
Query: 548 NPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQELEKRLL 607
E LK + E SA PP + S +
Sbjct: 1454 AASSPERKKRILKPQL--KSESSTSAFSTPTRSIPPRHNAAQINGKTESSSVVRTRSNRV 1511
Query: 608 DVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSESESSSSDLSSSDSSDSES 667
V+ + + + + KT +KA N S + + +S S++ ++ S SS S
Sbjct: 1512 VVDPVVTEQPSTSSAAKTFITKA--NASAIPGKTILENSVKHSKALNTLSSPGQSSFSHG 1569
Query: 668 EMFPKFTEVKPNDSPSKENVKKMKNECILPEGRT-----GVTQIGYCVQDTTSANTTLV- 721
+ K N K +KMK+ +LP+ T V + G C + T V
Sbjct: 1570 ---TRNNSAKENMEKEKPVKRKMKSS-VLPKASTLSKSSAVIEQGDCKNNALVPGTIQVN 1625
Query: 722 -HQTTPSHVMP--PNHH---QLAFNYQELEHLQTVKNISPLQILPPSGDSEQLSNGITVM 775
H PS ++ P ++ N E+ H + + LQ P D EQ + +
Sbjct: 1626 GHGGQPSKLVKRGPGRKPKVEVNTNSGEIIHKKRGRKPKKLQYAKPE-DLEQNN-----V 1679
Query: 776 HPSGD----SDTTMLESECQAPVQKDIKIKNADSWKSLGKPVKPSGVMKSSDELFNQFRK 831
HP D S T SE + ++ KN + KP + K +L
Sbjct: 1680 HPIRDEVLPSSTCNFLSETNNVKEDLLQKKN----RGGRKPKRKMKTQKLDADLLVPASV 1735
Query: 832 AAIEKEVKARTQELIRKHLEQNTKELKASQENQRDLGNGLTVESFSNKIQNKCSGEEQKE 891
+ + + + + I + E+ +ELK S+ + R G +F N+ S EEQ++
Sbjct: 1736 KVLRRSNRKKIDDPIDE--EEEFEELKGSEPHMRTRNQGRRT-AFYNEDD---SEEEQRQ 1789
Score = 50.1 bits (118), Expect = 1e-05
Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 52 FQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKP 111
F PVD P Y T++ P DL+TIK+RLEN++Y + S + + + N +N+P
Sbjct: 1184 FVAPVDLQAY--PMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFNEP 1241
Query: 112 GDDIVLMAQALEKLFM 127
G IV A+ + L +
Sbjct: 1242 GSPIVKSAKFVTDLLL 1257
Score = 38.1 bits (87), Expect = 0.039
Identities = 39/134 (29%), Positives = 56/134 (41%), Gaps = 8/134 (5%)
Query: 566 ELEKYVSACLRKRPLKPPAKKI-MMSKEELHSQKKQELEKRLLDVNNQLNSRKRQTKSDK 624
E++ Y S RK P KI +SK H + +L + NQ N R R +
Sbjct: 747 EIKTYRSEEKRKHLTVPKENKIPTVSKNHAH-EHFLDLGESKKQQTNQHNYRTRSALEET 805
Query: 625 TQPSKAVENVSRLSESS-----SSSSSSSESESSSSDLSSSD-SSDSESEMFPKFTEVKP 678
+PS+ +EN S S+ S +S E + SD SSSD SSD ++P
Sbjct: 806 PRPSEEIENGSSSSDEGEVVAVSGGTSEEEERAWHSDGSSSDYSSDYSDWTADAGINLQP 865
Query: 679 NDSPSKENVKKMKN 692
K KK ++
Sbjct: 866 PKKVPKNKTKKAES 879
Score = 33.5 bits (75), Expect = 0.96
Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 10/101 (9%)
Query: 397 TGRENTNEASSEGNSSDDSEDERVKRLAKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKS- 455
T E S+G+SSD S D + LQ +VP K K + S
Sbjct: 831 TSEEEERAWHSDGSSSDYSSD--------YSDWTADAGINLQPPKKVPKNKTKKAESSSD 882
Query: 456 -KKEKKKEKVNNSNENPRKMCEQMRLKEKSKRNQPKKRKQQ 495
++E +K+K + +K+ E+ K+ +PK+RKQ+
Sbjct: 883 EEEESEKQKQKQIKKEKKKVNEEKDGPISPKKKKPKERKQK 923
>gi|74027251 tripartite motif-containing 33 protein isoform beta [Homo
sapiens]
Length = 1110
Score = 64.7 bits (156), Expect = 4e-10
Identities = 40/139 (28%), Positives = 67/139 (48%), Gaps = 8/139 (5%)
Query: 43 LWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENK---YYAKASECIEDFN 99
L+ H S FQ PV A +P+YY IIK PMDL+T+KK+L+ K +Y + + D
Sbjct: 973 LYCHELSIEFQEPVPA---SIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVR 1029
Query: 100 TMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSA 159
+F NC +N+ ++ +A+ F KL+++ + + E ++ + S
Sbjct: 1030 LIFKNCERFNEADSEVAQAGKAVALYFEDKLTEIYSDRTFAPLPEFEQEEDDGEVTEDSD 1089
Query: 160 KEKSSPSATEKVFKQQEIP 178
++ P K K E P
Sbjct: 1090 EDFIQP--RRKRLKSDERP 1106
Score = 61.2 bits (147), Expect = 4e-09
Identities = 32/85 (37%), Positives = 48/85 (56%), Gaps = 6/85 (7%)
Query: 295 FYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMD---NQEYKDAYKFAADVRLMFMNCYKY 351
F PV + + NYY ++K PMDL T+K+K+ +Q Y+ F ADVRL+F NC ++
Sbjct: 982 FQEPVPAS---IPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERF 1038
Query: 352 NPPDHEVVTMARMLQDVFETHFSKI 376
N D EV + + FE ++I
Sbjct: 1039 NEADSEVAQAGKAVALYFEDKLTEI 1063
>gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens]
Length = 1872
Score = 64.7 bits (156), Expect = 4e-10
Identities = 44/153 (28%), Positives = 71/153 (46%), Gaps = 6/153 (3%)
Query: 35 LQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASEC 94
L +V + + SWPF PV+ K +PDYY +I NPMDL TI+K + Y
Sbjct: 1511 LDNIVTQKMMAVPDSWPFHHPVN--KKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESF 1568
Query: 95 IEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNI 154
++D N + +N YN P AQ + + Q L++ +E + +++ I T +
Sbjct: 1569 LDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTE--YDEHLTQLEKDI--CTAKEA 1624
Query: 155 AVSSAKEKSSPSATEKVFKQQEIPSVFPKTSIS 187
A+ A+ +S T + Q TS+S
Sbjct: 1625 ALEEAELESLDPMTPGPYTPQPPDLYDTNTSLS 1657
Score = 59.3 bits (142), Expect = 2e-08
Identities = 32/94 (34%), Positives = 53/94 (56%), Gaps = 4/94 (4%)
Query: 277 SEILKEMLAKKHFSY--AWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDA 334
S IL ++ +K + +WPF++PV N + +YY V+ NPMDL TI++ + +Y+
Sbjct: 1508 SFILDNIVTQKMMAVPDSWPFHHPV--NKKFVPDYYKVIVNPMDLETIRKNISKHKYQSR 1565
Query: 335 YKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDV 368
F DV L+ N KYN P+ + A+ + +V
Sbjct: 1566 ESFLDDVNLILANSVKYNGPESQYTKTAQEIVNV 1599
Score = 52.0 bits (123), Expect = 3e-06
Identities = 30/115 (26%), Positives = 60/115 (52%), Gaps = 4/115 (3%)
Query: 32 LQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKA 91
L + + ++ D+ ++PF PV+A ++ DYY II PMDL T+++ + + Y
Sbjct: 1385 LSSILESIINDMRDLPNTYPFHTPVNAKVVK--DYYKIITRPMDLQTLRENVRKRLYPSR 1442
Query: 92 SECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERI 146
E E + N YN P + ++Q++ L +KL + +E+++ +++ I
Sbjct: 1443 EEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKE--KEDKLARLEKAI 1495
Score = 50.1 bits (118), Expect = 1e-05
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 3/100 (3%)
Query: 270 TEQLRHCSEILKEMLAK-KHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDN 328
T+ + S IL+ ++ + +PF+ PV NA + +YY ++ PMDL T++E +
Sbjct: 1379 TDPMVTLSSILESIINDMRDLPNTYPFHTPV--NAKVVKDYYKIITRPMDLQTLRENVRK 1436
Query: 329 QEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDV 368
+ Y +F + L+ N YN P H + +++ + D+
Sbjct: 1437 RLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDL 1476
>gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens]
Length = 1893
Score = 64.7 bits (156), Expect = 4e-10
Identities = 44/153 (28%), Positives = 71/153 (46%), Gaps = 6/153 (3%)
Query: 35 LQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASEC 94
L +V + + SWPF PV+ K +PDYY +I NPMDL TI+K + Y
Sbjct: 1532 LDNIVTQKMMAVPDSWPFHHPVN--KKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESF 1589
Query: 95 IEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNI 154
++D N + +N YN P AQ + + Q L++ +E + +++ I T +
Sbjct: 1590 LDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTE--YDEHLTQLEKDI--CTAKEA 1645
Query: 155 AVSSAKEKSSPSATEKVFKQQEIPSVFPKTSIS 187
A+ A+ +S T + Q TS+S
Sbjct: 1646 ALEEAELESLDPMTPGPYTPQPPDLYDTNTSLS 1678
Score = 59.3 bits (142), Expect = 2e-08
Identities = 32/94 (34%), Positives = 53/94 (56%), Gaps = 4/94 (4%)
Query: 277 SEILKEMLAKKHFSY--AWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDA 334
S IL ++ +K + +WPF++PV N + +YY V+ NPMDL TI++ + +Y+
Sbjct: 1529 SFILDNIVTQKMMAVPDSWPFHHPV--NKKFVPDYYKVIVNPMDLETIRKNISKHKYQSR 1586
Query: 335 YKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDV 368
F DV L+ N KYN P+ + A+ + +V
Sbjct: 1587 ESFLDDVNLILANSVKYNGPESQYTKTAQEIVNV 1620
Score = 52.0 bits (123), Expect = 3e-06
Identities = 30/115 (26%), Positives = 60/115 (52%), Gaps = 4/115 (3%)
Query: 32 LQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKA 91
L + + ++ D+ ++PF PV+A ++ DYY II PMDL T+++ + + Y
Sbjct: 1406 LSSILESIINDMRDLPNTYPFHTPVNAKVVK--DYYKIITRPMDLQTLRENVRKRLYPSR 1463
Query: 92 SECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERI 146
E E + N YN P + ++Q++ L +KL + +E+++ +++ I
Sbjct: 1464 EEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKE--KEDKLARLEKAI 1516
Score = 50.1 bits (118), Expect = 1e-05
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 3/100 (3%)
Query: 270 TEQLRHCSEILKEMLAK-KHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDN 328
T+ + S IL+ ++ + +PF+ PV NA + +YY ++ PMDL T++E +
Sbjct: 1400 TDPMVTLSSILESIINDMRDLPNTYPFHTPV--NAKVVKDYYKIITRPMDLQTLRENVRK 1457
Query: 329 QEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDV 368
+ Y +F + L+ N YN P H + +++ + D+
Sbjct: 1458 RLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDL 1497
>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
sapiens]
Length = 1905
Score = 64.3 bits (155), Expect = 5e-10
Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
Query: 273 LRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYK 332
L C IL EM + AWPF PV+ + Y ++KNPMD T++E++ Y
Sbjct: 1799 LTFCEIILMEM---ESHDAAWPFLEPVNPRLVS--GYRRIIKNPMDFSTMRERLLRGGYT 1853
Query: 333 DAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSK 375
+ +FAAD L+F NC +N D EV +++ FE+ + +
Sbjct: 1854 SSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEE 1896
Score = 57.0 bits (136), Expect = 8e-08
Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 2/102 (1%)
Query: 37 KVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIE 96
+++L ++ H +WPF PV+ + Y IIKNPMD +T+++RL Y + E
Sbjct: 1803 EIILMEMESHDAAWPFLEPVNPRLVS--GYRRIIKNPMDFSTMRERLLRGGYTSSEEFAA 1860
Query: 97 DFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQ 138
D +F NC +N+ ++ + + F + + Q +Q
Sbjct: 1861 DALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQ 1902
Score = 42.4 bits (98), Expect = 0.002
Identities = 31/121 (25%), Positives = 63/121 (52%), Gaps = 6/121 (4%)
Query: 390 KTDITETTGRENTNEASSEGNSSDDSEDERVKRLAKLQEQLKAVHQQLQVLSQVPFRKLN 449
K ITE + + N + + + +E ++AK +++++ Q+ + + + + N
Sbjct: 678 KVKITELLNKTD-NRPLKKLEAQETLNEEDKAKIAKSKKKMRQKVQRGECQTTIQGQARN 736
Query: 450 KKKEKSKKEKKKE-KVNNSNENPRKMCEQMRLKEKSKRNQPKKRKQQFIGLKSEDEDNAK 508
K+K+++K K+KE K + E + +Q +LKEK KR + +K K + + E+ AK
Sbjct: 737 KRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKVKMK----EKEEVTKAK 792
Query: 509 P 509
P
Sbjct: 793 P 793
Score = 35.4 bits (80), Expect = 0.25
Identities = 29/119 (24%), Positives = 50/119 (42%), Gaps = 13/119 (10%)
Query: 822 SDELFNQFRKAAIEKEVKARTQEL------------IRKHLEQNTKELKASQENQRDLGN 869
+ E N+ KA I K K Q++ R +Q TK LK + ++
Sbjct: 698 AQETLNEEDKAKIAKSKKKMRQKVQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAE 757
Query: 870 GLTVESFSNKIQNKCSGEE-QKEHQQSSEAQDKSKLWLLKDRDLARQKEQERRRREAMV 927
++ K++ K E+ +K + E K+K D+ LA Q+ E R+R+ M+
Sbjct: 758 KEKGKTKQEKLKEKVKREKKEKVKMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMI 816
>gi|30794372 polybromo 1 isoform 1 [Homo sapiens]
Length = 1602
Score = 63.9 bits (154), Expect = 7e-10
Identities = 28/78 (35%), Positives = 45/78 (57%)
Query: 60 KLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMA 119
K+Q PDYY IIK P+DL TI +R++N Y +D + + N YN+PG + A
Sbjct: 214 KVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDA 273
Query: 120 QALEKLFMQKLSQMPQEE 137
+++K+F K +++ E
Sbjct: 274 NSIKKIFYMKKAEIEHHE 291
Score = 62.0 bits (149), Expect = 3e-09
Identities = 75/349 (21%), Positives = 129/349 (36%), Gaps = 47/349 (13%)
Query: 60 KLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMA 119
K + PDYY IK P+ L I+ +L+N+ Y D N MF N YN P I
Sbjct: 382 KKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRV 441
Query: 120 QALEKLFMQKLSQMPQEEQVVGVKERI----------KKGTQQNI----------AVSSA 159
L+++ K ++ + + + I K+ +++NI V A
Sbjct: 442 LKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEA 501
Query: 160 KEKSSPSATEKVFKQQEIPSVFP---KTSISP--LNVVQGASVNSSSQTAAQVTKGVK-- 212
+E S +F + +P K + P L +++ N + + +K
Sbjct: 502 REPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLM 561
Query: 213 -RKADTTTPATSAV------------KASSEFSPTFTEKSVALPPIKENMPKNVLPDSQQ 259
R A S V + E P + +A P +K + + P +
Sbjct: 562 FRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSK 621
Query: 260 QYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDL 319
++ ++L E +K K+ + F + L +YY +K PMD+
Sbjct: 622 YMTPMQ-----QKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELP--DYYLTIKKPMDM 674
Query: 320 GTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDV 368
I+ M +Y+D D +MF N YN P+ + A +L V
Sbjct: 675 EKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKV 723
Score = 53.1 bits (126), Expect = 1e-06
Identities = 26/76 (34%), Positives = 38/76 (50%)
Query: 62 QLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQA 121
+LPDYY IK PMD+ I+ + Y +EDF MF+N YN+P I A
Sbjct: 660 ELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALV 719
Query: 122 LEKLFMQKLSQMPQEE 137
L K+ ++ + +E
Sbjct: 720 LHKVLLETRRDLEGDE 735
Score = 52.8 bits (125), Expect = 2e-06
Identities = 75/374 (20%), Positives = 132/374 (35%), Gaps = 73/374 (19%)
Query: 64 PDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALE 123
PDYY ++ P+DL I+++L+ + Y + DF +F+N Y KP A L
Sbjct: 82 PDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLW 141
Query: 124 KLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQ--------- 174
L+++ ++ Q+ + E + Q N + E SSP+ +++ +Q
Sbjct: 142 DLYLRTRNEFVQKGE--ADDEDDDEDGQDN--QGTVTEGSSPAYLKEILEQLLEAIVVAT 197
Query: 175 -----------QEIPSVFPKTSI-----SPLNV------VQGASVNSSSQTAAQVTKGVK 212
Q++PS P+++ +Q S S A + K
Sbjct: 198 NPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAK 257
Query: 213 RKADTTTPATSAVKASSEFSPTFTEKSVALPPIKENMPKNVLPDSQQ---QYNVVKTVKV 269
P + K ++ F K + M K+ L S + Q + + +
Sbjct: 258 NAKTYNEPGSQVFKDANSIKKIFYMKKAEIE--HHEMAKSSLRMSNKRAVQGGRLSAITM 315
Query: 270 TEQLRHCSEILKEMLAKKH-------------FSYAWPFYNPVDVNALGLHNYYDVVKNP 316
Q SE + A ++ + PFY D +N ++ P
Sbjct: 316 ALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEP 375
Query: 317 --------------------MDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDH 356
+ L I+ K+ NQEY+ D+ LMF N +YN P+
Sbjct: 376 FYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNS 435
Query: 357 EVVTMARMLQDVFE 370
+ LQ V +
Sbjct: 436 AIYKRVLKLQQVMQ 449
Score = 50.1 bits (118), Expect = 1e-05
Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 2/72 (2%)
Query: 308 NYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQD 367
+YY ++K P+DL TI +++ N YK + A D+ L+ N YN P +V A ++
Sbjct: 219 DYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKK 278
Query: 368 VFETHFSKIPIE 379
+F + K IE
Sbjct: 279 IF--YMKKAEIE 288
Score = 43.5 bits (101), Expect = 0.001
Identities = 37/186 (19%), Positives = 74/186 (39%), Gaps = 3/186 (1%)
Query: 308 NYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQD 367
+YY ++ PMDL I+ + N +Y D++LMF N YN +V A +L+
Sbjct: 525 DYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEK 584
Query: 368 VFETHFSKI-PIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERVKRLAKL 426
+ + ++ P+ + M +K + + + ++ + K
Sbjct: 585 LLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKR 644
Query: 427 QEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQ--MRLKEKS 484
+L A+ +L S++P L KK ++ + + N ++ M E M
Sbjct: 645 GRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNAC 704
Query: 485 KRNQPK 490
N+P+
Sbjct: 705 TYNEPE 710
>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
Length = 1216
Score = 63.5 bits (153), Expect = 9e-10
Identities = 34/86 (39%), Positives = 47/86 (54%), Gaps = 6/86 (6%)
Query: 294 PFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQE---YKDAYKFAADVRLMFMNCYK 350
PF+ PV A +YY ++K PMDL I+ K+ ++ Y + +DVRLMF NC K
Sbjct: 1065 PFHEPVSPLA---RHYYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAK 1121
Query: 351 YNPPDHEVVTMARMLQDVFETHFSKI 376
+N PD EV R L+ FE +I
Sbjct: 1122 FNYPDSEVAEAGRCLEVFFEGWLKEI 1147
Score = 57.4 bits (137), Expect = 6e-08
Identities = 35/106 (33%), Positives = 55/106 (51%), Gaps = 7/106 (6%)
Query: 36 QKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENK---YYAKAS 92
+K+VL L ++ S PF PV + YY IIK PMDL+ I+++L+ K +Y
Sbjct: 1051 EKLVLS-LCCNNLSLPFHEPVSPLARH---YYQIIKRPMDLSIIRRKLQKKDPAHYTTPE 1106
Query: 93 ECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQ 138
E + D MF NC +N P ++ + LE F L ++ E++
Sbjct: 1107 EVVSDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEIYPEKR 1152
>gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo
sapiens]
Length = 1826
Score = 62.8 bits (151), Expect = 1e-09
Identities = 42/153 (27%), Positives = 71/153 (46%), Gaps = 6/153 (3%)
Query: 35 LQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASEC 94
L +V + + SWPF PV+ K +PDYY +I NP+DL TI+K + Y
Sbjct: 1530 LDNIVTQKMMAVPDSWPFHHPVN--KKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESF 1587
Query: 95 IEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNI 154
++D N + +N YN P AQ + + Q +++ +E + +++ I T +
Sbjct: 1588 LDDVNLILANSVKYNGPESQYTKTAQEIVNICYQTITE--YDEHLTQLEKDI--CTAKEA 1643
Query: 155 AVSSAKEKSSPSATEKVFKQQEIPSVFPKTSIS 187
A+ A+ +S T + Q TS+S
Sbjct: 1644 ALEEAELESLDPMTPGPYTSQPPDMYDTNTSLS 1676
Score = 56.2 bits (134), Expect = 1e-07
Identities = 29/94 (30%), Positives = 53/94 (56%), Gaps = 4/94 (4%)
Query: 277 SEILKEMLAKKHFSY--AWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDA 334
S IL ++ +K + +WPF++PV N + +YY ++ NP+DL TI++ + +Y+
Sbjct: 1527 SFILDNIVTQKMMAVPDSWPFHHPV--NKKFVPDYYKMIVNPVDLETIRKNISKHKYQSR 1584
Query: 335 YKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDV 368
F DV L+ N KYN P+ + A+ + ++
Sbjct: 1585 ESFLDDVNLILANSVKYNGPESQYTKTAQEIVNI 1618
Score = 48.5 bits (114), Expect = 3e-05
Identities = 30/115 (26%), Positives = 58/115 (50%), Gaps = 4/115 (3%)
Query: 32 LQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKA 91
L + + ++ D+ + PF PV+A ++ DYY II PMDL T+++ + Y
Sbjct: 1404 LSSILESIINDMRDLPNTHPFHTPVNAKVVK--DYYKIITRPMDLQTLRENVRKCLYPSR 1461
Query: 92 SECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERI 146
E E + N YN P + ++Q++ L +KL + +E+++ +++ I
Sbjct: 1462 EEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKE--KEDKLARLEKAI 1514
Score = 47.4 bits (111), Expect = 6e-05
Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 294 PFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNP 353
PF+ PV NA + +YY ++ PMDL T++E + Y +F + L+ N YN
Sbjct: 1423 PFHTPV--NAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNG 1480
Query: 354 PDHEVVTMARMLQDV 368
P H + +++ + D+
Sbjct: 1481 PKHSLTQISQSMLDL 1495
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.125 0.342
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,559,154
Number of Sequences: 37866
Number of extensions: 1660637
Number of successful extensions: 21549
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 324
Number of HSP's successfully gapped in prelim test: 880
Number of HSP's that attempted gapping in prelim test: 11052
Number of HSP's gapped (non-prelim): 6698
length of query: 947
length of database: 18,247,518
effective HSP length: 112
effective length of query: 835
effective length of database: 14,006,526
effective search space: 11695449210
effective search space used: 11695449210
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.