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Search of human proteins with 45580730
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo
sapiens]
(1098 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens] 2223 0.0
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] 68 5e-11
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] 68 5e-11
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho... 52 4e-06
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H... 51 5e-06
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s... 51 7e-06
gi|13236579 solute carrier family 27 member 3 [Homo sapiens] 50 2e-05
gi|13325057 solute carrier family 27 (fatty acid transporter), m... 47 8e-05
gi|253970489 acyl-CoA synthetase short-chain family member 2 iso... 47 1e-04
gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo... 47 1e-04
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] 46 2e-04
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom... 44 0.001
gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo... 43 0.002
gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo... 43 0.002
gi|42794756 acyl-CoA synthetase long-chain family member 5 isofo... 43 0.002
gi|32189425 WD repeat domain 69 [Homo sapiens] 42 0.002
gi|31982927 acetoacetyl-CoA synthetase [Homo sapiens] 41 0.007
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 40 0.009
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 40 0.009
gi|145312265 endoplasmic reticulum to nucleus signalling 2 [Homo... 40 0.016
gi|58331161 PHD finger protein 19 isoform a [Homo sapiens] 40 0.016
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H... 38 0.046
gi|153946421 endoplasmic reticulum to nucleus signalling 1 [Homo... 36 0.23
gi|13376840 WD repeat domain 61 [Homo sapiens] 35 0.30
gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s... 35 0.39
gi|27477105 lipidosin [Homo sapiens] 35 0.39
gi|13375727 acyl-CoA synthetase short-chain family member 3 [Hom... 35 0.39
gi|6912356 echinoderm microtubule associated protein like 2 [Hom... 35 0.39
gi|57165412 acyl-CoA synthetase long-chain family member 6 isofo... 35 0.51
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [... 35 0.51
>gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens]
Length = 1098
Score = 2223 bits (5761), Expect = 0.0
Identities = 1098/1098 (100%), Positives = 1098/1098 (100%)
Query: 1 MTLQELVHKAASCYMDRVAVCFDECNNQLPVYYTYKTVVNAASELSNFLLLHCDFQGIRE 60
MTLQELVHKAASCYMDRVAVCFDECNNQLPVYYTYKTVVNAASELSNFLLLHCDFQGIRE
Sbjct: 1 MTLQELVHKAASCYMDRVAVCFDECNNQLPVYYTYKTVVNAASELSNFLLLHCDFQGIRE 60
Query: 61 IGLYCQPGIDLPSWILGILQVPAAYVPIEPDSPPSLSTHFMKKCNLKYILVEKKQINKFK 120
IGLYCQPGIDLPSWILGILQVPAAYVPIEPDSPPSLSTHFMKKCNLKYILVEKKQINKFK
Sbjct: 61 IGLYCQPGIDLPSWILGILQVPAAYVPIEPDSPPSLSTHFMKKCNLKYILVEKKQINKFK 120
Query: 121 SFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKA 180
SFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKA
Sbjct: 121 SFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKA 180
Query: 181 EEHMDLRLKHCLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPL 240
EEHMDLRLKHCLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPL
Sbjct: 181 EEHMDLRLKHCLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPL 240
Query: 241 TFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRRFGSQL 300
TFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRRFGSQL
Sbjct: 241 TFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRRFGSQL 300
Query: 301 IKSTVLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPE 360
IKSTVLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPE
Sbjct: 301 IKSTVLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPE 360
Query: 361 KTLNSTLKCELPVQLGFPLLGTVVEVRDTNGFTIQEGSGQVFLGGRNRVCFLDDEVTVPL 420
KTLNSTLKCELPVQLGFPLLGTVVEVRDTNGFTIQEGSGQVFLGGRNRVCFLDDEVTVPL
Sbjct: 361 KTLNSTLKCELPVQLGFPLLGTVVEVRDTNGFTIQEGSGQVFLGGRNRVCFLDDEVTVPL 420
Query: 421 GTMRATGDFVTVKDGEIFFLGRKDSQIKRHGKRLNIELVQQVAEELQQVESCAVTWYNQE 480
GTMRATGDFVTVKDGEIFFLGRKDSQIKRHGKRLNIELVQQVAEELQQVESCAVTWYNQE
Sbjct: 421 GTMRATGDFVTVKDGEIFFLGRKDSQIKRHGKRLNIELVQQVAEELQQVESCAVTWYNQE 480
Query: 481 KLILFMVSKDASVKEYIFKELQKYLPSHAVPDELVLIDSLPFTSHGKIDVSELNKIYLNY 540
KLILFMVSKDASVKEYIFKELQKYLPSHAVPDELVLIDSLPFTSHGKIDVSELNKIYLNY
Sbjct: 481 KLILFMVSKDASVKEYIFKELQKYLPSHAVPDELVLIDSLPFTSHGKIDVSELNKIYLNY 540
Query: 541 INLKSENKLSGKEDLWEKLQYLWKSTLNLPEDLLRVPDESLFLNSGGDSLKSIRLLSEIE 600
INLKSENKLSGKEDLWEKLQYLWKSTLNLPEDLLRVPDESLFLNSGGDSLKSIRLLSEIE
Sbjct: 541 INLKSENKLSGKEDLWEKLQYLWKSTLNLPEDLLRVPDESLFLNSGGDSLKSIRLLSEIE 600
Query: 601 KLVGTSVPGLLEIILSSSILEIYNHILQTVVPDEDVTFRKSCATKRKLSDINQEEASGTS 660
KLVGTSVPGLLEIILSSSILEIYNHILQTVVPDEDVTFRKSCATKRKLSDINQEEASGTS
Sbjct: 601 KLVGTSVPGLLEIILSSSILEIYNHILQTVVPDEDVTFRKSCATKRKLSDINQEEASGTS 660
Query: 661 LHQKAIMTFTCHNEINAFVVLSRGSQILSLNSTRFLTKLGHCSSACPSDSVSQTNIQNLK 720
LHQKAIMTFTCHNEINAFVVLSRGSQILSLNSTRFLTKLGHCSSACPSDSVSQTNIQNLK
Sbjct: 661 LHQKAIMTFTCHNEINAFVVLSRGSQILSLNSTRFLTKLGHCSSACPSDSVSQTNIQNLK 720
Query: 721 GLNSPVLIGKSKDPSCVAKVSEEGKPAIGTQKMELHVRWRSDTGKCVDASPLVVIPTFDK 780
GLNSPVLIGKSKDPSCVAKVSEEGKPAIGTQKMELHVRWRSDTGKCVDASPLVVIPTFDK
Sbjct: 721 GLNSPVLIGKSKDPSCVAKVSEEGKPAIGTQKMELHVRWRSDTGKCVDASPLVVIPTFDK 780
Query: 781 SSTTVYIGSHSHRMKAVDFYSGKVKWEQILGDRIESSACVSKCGNFIVVGCYNGLVYVLK 840
SSTTVYIGSHSHRMKAVDFYSGKVKWEQILGDRIESSACVSKCGNFIVVGCYNGLVYVLK
Sbjct: 781 SSTTVYIGSHSHRMKAVDFYSGKVKWEQILGDRIESSACVSKCGNFIVVGCYNGLVYVLK 840
Query: 841 SNSGEKYWMFTTEDAVKSSATMDPTTGLIYIGSHDQHAYALDIYRKKCVWKSKCGGTVFS 900
SNSGEKYWMFTTEDAVKSSATMDPTTGLIYIGSHDQHAYALDIYRKKCVWKSKCGGTVFS
Sbjct: 841 SNSGEKYWMFTTEDAVKSSATMDPTTGLIYIGSHDQHAYALDIYRKKCVWKSKCGGTVFS 900
Query: 901 SPCLNLIPHHLYFATLGGLLLAVNPATGNVIWKHSCGKPLFSSPQCCSQYICIGCVDGNL 960
SPCLNLIPHHLYFATLGGLLLAVNPATGNVIWKHSCGKPLFSSPQCCSQYICIGCVDGNL
Sbjct: 901 SPCLNLIPHHLYFATLGGLLLAVNPATGNVIWKHSCGKPLFSSPQCCSQYICIGCVDGNL 960
Query: 961 LCFTHFGEQVWQFSTSGPIFSSPCTSPSEQKIFFGSHDCFIYCCNMKGHLQWKFETTSRV 1020
LCFTHFGEQVWQFSTSGPIFSSPCTSPSEQKIFFGSHDCFIYCCNMKGHLQWKFETTSRV
Sbjct: 961 LCFTHFGEQVWQFSTSGPIFSSPCTSPSEQKIFFGSHDCFIYCCNMKGHLQWKFETTSRV 1020
Query: 1021 YATPFAFHNYNGSNEMLLAAASTDGKVWILESQSGQLQSVYELPGEVFSSPVVLESMLII 1080
YATPFAFHNYNGSNEMLLAAASTDGKVWILESQSGQLQSVYELPGEVFSSPVVLESMLII
Sbjct: 1021 YATPFAFHNYNGSNEMLLAAASTDGKVWILESQSGQLQSVYELPGEVFSSPVVLESMLII 1080
Query: 1081 GCRDNYVYCLDLLGGNQK 1098
GCRDNYVYCLDLLGGNQK
Sbjct: 1081 GCRDNYVYCLDLLGGNQK 1098
>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 67.8 bits (164), Expect = 5e-11
Identities = 101/389 (25%), Positives = 156/389 (40%), Gaps = 64/389 (16%)
Query: 193 AYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPSVVEIFLA 252
A +++TSGTTG PK V H+ I + + T++DV+ PL VV L
Sbjct: 197 AMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLC 256
Query: 253 -LSSGASLLIVPTSVKLLPSKLASVLFSHH--RVTVLQATPTLLR-------RFGSQLIK 302
L GA+ +++P + P ++ S R+ V A PT+ R +Q
Sbjct: 257 PLWVGATCVMMP---EFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHA 313
Query: 303 STVLSATTS--LRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPE 360
L A +R++ G A P L VL W+ T + YG+TE+
Sbjct: 314 QDFLRAVCEEKIRLMVSGSAALP-LPVLEKWKNITGHT-LLERYGMTEIGM--------- 362
Query: 361 KTLNS--TLKCELPVQLGFPLLGTVVEV------RDTNGFTI---------------QEG 397
L+ T LP +G PL G V + R+ +TI +E
Sbjct: 363 -ALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEK 421
Query: 398 SGQVFLGGRN--RVCFLDDEVTVPLGTMRA---TGDFVTVKDGEIFFLGRKDSQIKRHG- 451
G++ + G + R + E T T+ TGD V KDG+ + GR I + G
Sbjct: 422 EGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTGG 481
Query: 452 ---KRLNIE---LVQQVAEELQQVESCAVTWYNQEKLILFMVSKDASVKEYIFKE-LQKY 504
L +E L ++ + +TW Q + + + S+ KE +
Sbjct: 482 YKVSALEVEWHLLAHPSITDVAVIGVPDMTW-GQRVTAVVTLREGHSLSHRELKEWARNV 540
Query: 505 LPSHAVPDELVLIDSLPFTSHGKIDVSEL 533
L +AVP ELVL++ +P GKID L
Sbjct: 541 LAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 67.8 bits (164), Expect = 5e-11
Identities = 101/389 (25%), Positives = 156/389 (40%), Gaps = 64/389 (16%)
Query: 193 AYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPSVVEIFLA 252
A +++TSGTTG PK V H+ I + + T++DV+ PL VV L
Sbjct: 197 AMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLC 256
Query: 253 -LSSGASLLIVPTSVKLLPSKLASVLFSHH--RVTVLQATPTLLR-------RFGSQLIK 302
L GA+ +++P + P ++ S R+ V A PT+ R +Q
Sbjct: 257 PLWVGATCVMMP---EFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHA 313
Query: 303 STVLSATTS--LRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPE 360
L A +R++ G A P L VL W+ T + YG+TE+
Sbjct: 314 QDFLRAVCEEKIRLMVSGSAALP-LPVLEKWKNITGHT-LLERYGMTEIGM--------- 362
Query: 361 KTLNS--TLKCELPVQLGFPLLGTVVEV------RDTNGFTI---------------QEG 397
L+ T LP +G PL G V + R+ +TI +E
Sbjct: 363 -ALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEK 421
Query: 398 SGQVFLGGRN--RVCFLDDEVTVPLGTMRA---TGDFVTVKDGEIFFLGRKDSQIKRHG- 451
G++ + G + R + E T T+ TGD V KDG+ + GR I + G
Sbjct: 422 EGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTGG 481
Query: 452 ---KRLNIE---LVQQVAEELQQVESCAVTWYNQEKLILFMVSKDASVKEYIFKE-LQKY 504
L +E L ++ + +TW Q + + + S+ KE +
Sbjct: 482 YKVSALEVEWHLLAHPSITDVAVIGVPDMTW-GQRVTAVVTLREGHSLSHRELKEWARNV 540
Query: 505 LPSHAVPDELVLIDSLPFTSHGKIDVSEL 533
L +AVP ELVL++ +P GKID L
Sbjct: 541 LAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
sapiens]
Length = 579
Score = 51.6 bits (122), Expect = 4e-06
Identities = 84/380 (22%), Positives = 152/380 (40%), Gaps = 40/380 (10%)
Query: 178 EKAEEHMDLRLKHCLAYVLH-TSGTTGIPKIVRVPHKCI-VPNIQHFRVLFDITQEDVLF 235
E + EH +R K ++ TSGTTG PK+V + + R +T+ D+ +
Sbjct: 209 EASTEHNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFW 268
Query: 236 LASPLTFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRR 295
+ + + +F A +G+ + + + + +K+ S +T L PT+ R
Sbjct: 269 NTTDTGWVKAAWTLFSAWPNGSCIFV--HELPRVDAKVILNTLSKFPITTLCCVPTIFRL 326
Query: 296 FGSQLIKSTVLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATI 355
+ + SLR GGEA + V W+ + +++ YG +E
Sbjct: 327 LVQEDLTRYQFQ---SLRHCLTGGEAL-NPDVREKWKHQTG-VELYEGYGQSETVVICAN 381
Query: 356 YRIPEKTLNSTLKCELPVQLGFPLLGTVVEVRDTNGFTI---QEGSGQVFLGGRNRVCFL 412
+ + S K P V++ D G + +EG+ V + CF
Sbjct: 382 PKGMKIKSGSMGKASPPYD---------VQIVDDEGNVLPPGEEGNVAVRIRPTRPFCFF 432
Query: 413 DDEVTVPLGTMRAT-GDFVTV-------KDGEIFFLGRKDSQIKRHGKRLN-IELVQQVA 463
+ + P T + GDF KDG +F+GR D I R+ +E+ +A
Sbjct: 433 NCYLDNPEKTAASEQGDFYITGDRARMDKDGYFWFMGRNDDVINSSSYRIGPVEVESALA 492
Query: 464 EELQQVESCAVTWYNQ------EKLILFMVSKDASVKEYIFKELQKYL----PSHAVPDE 513
E +ES V+ + + I+ + + E + +ELQ+++ + P +
Sbjct: 493 EHPAVLESAVVSSPDPIRGEVVKAFIVLTPAYSSHDPEALTRELQEHVKRVTAPYKYPRK 552
Query: 514 LVLIDSLPFTSHGKIDVSEL 533
+ + LP T GKI S+L
Sbjct: 553 VAFVSELPKTVSGKIQRSKL 572
>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
sapiens]
Length = 580
Score = 51.2 bits (121), Expect = 5e-06
Identities = 88/358 (24%), Positives = 143/358 (39%), Gaps = 40/358 (11%)
Query: 195 VLHTSGTTGIPKIVRVPHKCI-VPNIQHFRVLFDITQEDVLFLASPLTFDPSVV-EIFLA 252
+ TSGTTG PK+ + + + R D+ D+++ S + + + +F +
Sbjct: 226 IYFTSGTTGFPKMAQHSQSSLGIGFTLCGRYWLDLKSSDIIWNMSDTGWVKAAIGSVFSS 285
Query: 253 LSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRRFGSQLIKSTVLSATTSL 312
GA + + + + L ++ + + +T L + PT+ R + +K SL
Sbjct: 286 WLCGACVFVHRMAQFDTDTFLDTL--TTYPITTLCSPPTVYRMLVQKDLKRYKFK---SL 340
Query: 313 RVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPEKTLNSTLKCELP 372
R GGE + VL WR + +++ YG TEV I +K P
Sbjct: 341 RHCLTGGEPL-NPEVLEQWRVQ-TGLELYEGYGQTEVG------MICANQKGQEIK---P 389
Query: 373 VQLGFPLLGTVVEVRDTNGFTI---QEGSGQVFLGGRNRVCFLDDEVTVPLGTMRA-TGD 428
+G +L V++ D NG + +EG + L CF V P T GD
Sbjct: 390 GSMGKGMLPYDVQIIDENGNVLPPGKEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGD 449
Query: 429 F-------VTVKDGEIFFLGRKDSQIKRHGKRLN-IELVQQVAEELQQVESCAVTWYNQ- 479
F V DG +F+GR D I G R+ E+ + E VES V+ +Q
Sbjct: 450 FYVTGDRGVMDSDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDQI 509
Query: 480 -EKLILFMVSKDASVKEYIFKELQKYLPSHA--------VPDELVLIDSLPFTSHGKI 528
+++ V A K Y ++L L H P ++ + LP T GKI
Sbjct: 510 RGEVVKAFVVLAAPFKSYNPEKLTLELQDHVKKSTAPYKYPRKVEFVQELPKTITGKI 567
>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
sapiens]
Length = 586
Score = 50.8 bits (120), Expect = 7e-06
Identities = 95/383 (24%), Positives = 153/383 (39%), Gaps = 45/383 (11%)
Query: 180 AEEHMDLRLKHC-LAYVLHTSGTTGIPKIVRVPHKCIVPNIQ-HFRVLFDITQEDVLFLA 237
++ H ++ KH + + TSGT+G PK+ H + + R D+T DV++
Sbjct: 216 SDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNT 275
Query: 238 SPLTFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRRFG 297
S + S + + + + P+ + L S + +TV + PT+ R
Sbjct: 276 SDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTSILQTL-SKYPITVFCSAPTVYR--- 331
Query: 298 SQLIKSTVLS-ATTSLRVLALGGEAFPSLTVLRSWRGEGNKT--QIFNVYGITEVSSWAT 354
L+++ + S SL+ GE + V WR NKT I+ YG TE
Sbjct: 332 -MLVQNDITSYKFKSLKHCVSAGEPI-TPDVTEKWR---NKTGLDIYEGYGQTETVLICG 386
Query: 355 IYRIPEKTLNSTLKCELPVQLGFPLLGTVVEVRDTNGFTI---QEGS-GQVFLGGRNRVC 410
++ +K P +G P V++ D NG + QEG G L R
Sbjct: 387 NFK------GMKIK---PGSMGKPSPAFDVKIVDVNGNVLPPGQEGDIGIQVLPNRPFGL 437
Query: 411 FLD--DEVTVPLGTMRA----TGDFVTV-KDGEIFFLGRKDSQIKRHGKRLNIELVQQVA 463
F D + T+R TGD + KDG +F+ R D I G R+ V+
Sbjct: 438 FTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFWFVARADDVILSSGYRIGPFEVENAL 497
Query: 464 EELQQVESCAVTW----YNQEKLILFMV---SKDASVKEYIFKELQKYLPS----HAVPD 512
E V AV E + F+V + +E + KE+Q+++ + P
Sbjct: 498 NEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSHDQEQLIKEIQEHVKKTTAPYKYPR 557
Query: 513 ELVLIDSLPFTSHGKIDVSELNK 535
++ I LP T GK +EL K
Sbjct: 558 KVEFIQELPKTISGKTKRNELRK 580
>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
Length = 730
Score = 49.7 bits (117), Expect = 2e-05
Identities = 51/158 (32%), Positives = 70/158 (44%), Gaps = 19/158 (12%)
Query: 196 LHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPL-TFDPSVVEIFLALS 254
+ TSGTTG+PK R+ H I+ Q F L + QEDV++LA PL S++ I +
Sbjct: 333 IFTSGTTGLPKAARISHLKIL-QCQGFYQLCGVHQEDVIYLALPLYHMSGSLLGIVGCMG 391
Query: 255 SGASLLIVPTSVKLLPSKLASVLF----SHHRVTVLQATPTLLRRFGSQLIKSTVLSATT 310
GA++ +L SK ++ F HRVTV Q L R L+ A
Sbjct: 392 IGATV--------VLKSKFSAGQFWEDCQQHRVTVFQYIGELCR----YLVNQPPSKAER 439
Query: 311 SLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITE 348
+V G T R R G Q+ YG+TE
Sbjct: 440 GHKVRLAVGSGLRPDTWERFVRRFG-PLQVLETYGLTE 476
>gi|13325057 solute carrier family 27 (fatty acid transporter),
member 5 [Homo sapiens]
Length = 690
Score = 47.4 bits (111), Expect = 8e-05
Identities = 87/369 (23%), Positives = 153/369 (41%), Gaps = 48/369 (13%)
Query: 193 AYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPS-VVEIFL 251
A ++TSGTTG+PK + H+ ++ + L T +DV++ PL VV I
Sbjct: 290 ALFIYTSGTTGLPKPAILTHERVL-QMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILG 348
Query: 252 ALSSGASLLIVPTSVKLLPSKLASVLF----SHHRVTVLQATPTLLRRFGSQLIKSTVLS 307
L GA+ ++ P K ++ F H VTV+ LLR + I
Sbjct: 349 CLDLGATCVLAP--------KFSTSCFWDDCRQHGVTVILYVGELLRYLCN--IPQQPED 398
Query: 308 ATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPEKTLNSTL 367
T ++R LA+G V +++ +I+ VYG TE + + + +
Sbjct: 399 RTHTVR-LAMGNGL--RADVWETFQQRFGPIRIWEVYGSTE-GNMGLVNYVGRCGALGKM 454
Query: 368 KCELPVQLGFPLLGTVVE----VRDTNGFTIQEGSG------------QVFLGGRNRVCF 411
C L + F L+ +E VRD GF I G G Q F+G R
Sbjct: 455 SCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPREL 514
Query: 412 LDDEVTVPL----GTMRATGDFVTV-KDGEIFFLGRKDSQIKRHGKRLNIELVQQVAEE- 465
+ ++ + TGD + + ++G ++F R + G+ ++ V+ V +
Sbjct: 515 SERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQV 574
Query: 466 --LQQVESCAVTWYNQEKLILFMVSKDASVK----EYIFKELQKYLPSHAVPDELVLIDS 519
LQQV V E + + A + E +++ ++ +LP++A P + + D+
Sbjct: 575 DFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDA 634
Query: 520 LPFTSHGKI 528
+ TS K+
Sbjct: 635 MEVTSTFKL 643
>gi|253970489 acyl-CoA synthetase short-chain family member 2
isoform 2 [Homo sapiens]
Length = 714
Score = 47.0 bits (110), Expect = 1e-04
Identities = 89/376 (23%), Positives = 153/376 (40%), Gaps = 44/376 (11%)
Query: 194 YVLHTSGTTGIPK-IVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPSVVEI-FL 251
++L+TSG+TG PK +V ++ F+ +FD EDV + + + + + +
Sbjct: 325 FILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYG 384
Query: 252 ALSSGASLLI---VPTSVKLLPSKLASVLFSHHRVTVLQATPT---LLRRFGSQLIKSTV 305
L++GA+ ++ +PT + ++L S++ ++VT PT LL +FG + +
Sbjct: 385 PLANGATSVLFEGIPTYPDV--NRLWSIV-DKYKVTKFYTAPTAIRLLMKFGDEPVTK-- 439
Query: 306 LSATTSLRVLALGGEAFPSLTVLRSWRGEG-NKTQIFNVYGITEVSSWATIYRIPEKTLN 364
+ SL+VL GE L R G + I + + TE + +P T
Sbjct: 440 -HSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHM-LTPLPGATPM 497
Query: 365 STLKCELPVQLGFPLLGTVVEVRDTNGFTIQEGSGQVFL------GGRNRVCFLDDEVTV 418
P FP G + + +G + EG + +L G R + + E
Sbjct: 498 K------PGSATFPFFGVAPAILNESGEEL-EGEAEGYLVFKQPWPGIMRTVYGNHERFE 550
Query: 419 PLGTMRATGDFVTV------KDGEIFFLGRKDSQIKRHGKRLNIELVQQVAEELQQVESC 472
+ G +VT +DG + GR D + G L+ V+ E + V
Sbjct: 551 TTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEA 610
Query: 473 AVTWYNQ----EKLILFMVSKDA-----SVKEYIFKELQKYLPSHAVPDELVLIDSLPFT 523
AV + E L F+ D + E + K++++ + A PD + LP T
Sbjct: 611 AVVGHPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDYIQNAPGLPKT 670
Query: 524 SHGKIDVSELNKIYLN 539
GKI L KI N
Sbjct: 671 RSGKIMRRVLRKIAQN 686
>gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform
1 [Homo sapiens]
Length = 701
Score = 47.0 bits (110), Expect = 1e-04
Identities = 89/376 (23%), Positives = 153/376 (40%), Gaps = 44/376 (11%)
Query: 194 YVLHTSGTTGIPK-IVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPSVVEI-FL 251
++L+TSG+TG PK +V ++ F+ +FD EDV + + + + + +
Sbjct: 312 FILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYG 371
Query: 252 ALSSGASLLI---VPTSVKLLPSKLASVLFSHHRVTVLQATPT---LLRRFGSQLIKSTV 305
L++GA+ ++ +PT + ++L S++ ++VT PT LL +FG + +
Sbjct: 372 PLANGATSVLFEGIPTYPDV--NRLWSIV-DKYKVTKFYTAPTAIRLLMKFGDEPVTK-- 426
Query: 306 LSATTSLRVLALGGEAFPSLTVLRSWRGEG-NKTQIFNVYGITEVSSWATIYRIPEKTLN 364
+ SL+VL GE L R G + I + + TE + +P T
Sbjct: 427 -HSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHM-LTPLPGATPM 484
Query: 365 STLKCELPVQLGFPLLGTVVEVRDTNGFTIQEGSGQVFL------GGRNRVCFLDDEVTV 418
P FP G + + +G + EG + +L G R + + E
Sbjct: 485 K------PGSATFPFFGVAPAILNESGEEL-EGEAEGYLVFKQPWPGIMRTVYGNHERFE 537
Query: 419 PLGTMRATGDFVTV------KDGEIFFLGRKDSQIKRHGKRLNIELVQQVAEELQQVESC 472
+ G +VT +DG + GR D + G L+ V+ E + V
Sbjct: 538 TTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEA 597
Query: 473 AVTWYNQ----EKLILFMVSKDA-----SVKEYIFKELQKYLPSHAVPDELVLIDSLPFT 523
AV + E L F+ D + E + K++++ + A PD + LP T
Sbjct: 598 AVVGHPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDYIQNAPGLPKT 657
Query: 524 SHGKIDVSELNKIYLN 539
GKI L KI N
Sbjct: 658 RSGKIMRRVLRKIAQN 673
>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
Length = 615
Score = 45.8 bits (107), Expect = 2e-04
Identities = 91/370 (24%), Positives = 149/370 (40%), Gaps = 41/370 (11%)
Query: 198 TSGTTGIPKIVRVPHKCIVPN---IQHFRVLFDITQEDV-LFLASPLTFD-PSVVEIFLA 252
TSGTTG PK + H IV N + L + T E + + L +PL SV +
Sbjct: 263 TSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGTMMC 322
Query: 253 LSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRRFGSQLIKSTVLSATTSL 312
L GA+L++ + + K A S R T L TPT+ +Q S+ +T
Sbjct: 323 LMYGATLIL---ASPIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCG 379
Query: 313 RVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPEKTLNSTLKCELP 372
V+A G A P L +R+ + N + YG TE +S T PE T+ +
Sbjct: 380 GVIA-GSPAPPEL--IRAIINKINMKDLVVAYGTTE-NSPVTFAHFPEDTVEQKAE---- 431
Query: 373 VQLGFPLLGTVVEVRDTNGFTIQE--GSGQVFLGGRNRVCFLDDEVTVPLGTMRA----- 425
+G + T + + T+ + G++ + G C + P T A
Sbjct: 432 -SVGRIMPHTEARIMNMEAGTLAKLNTPGELCIRG---YCVMLGYWGEPQKTEEAVDQDK 487
Query: 426 ---TGDFVTVKD-GEIFFLGRKDSQIKRHGKRLNIELVQQVAEELQQVESCAVTWYNQEK 481
TGD T+ + G +GR I R G+ + ++ +V+ V ++
Sbjct: 488 WYWTGDVATMNEQGFCKIVGRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVKDDR 547
Query: 482 L-------ILFMVSKDASVKEYIFKELQKYLPSH-AVPDELVLIDSLPFTSHGKIDVSEL 533
+ I ++ +V+E K K SH +P +V + + P T GKI +L
Sbjct: 548 MGEEICACIRLKDGEETTVEE--IKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFKL 605
Query: 534 NKIYLNYINL 543
+ ++NL
Sbjct: 606 REQMERHLNL 615
>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
sapiens]
Length = 689
Score = 43.5 bits (101), Expect = 0.001
Identities = 83/372 (22%), Positives = 143/372 (38%), Gaps = 35/372 (9%)
Query: 192 LAYVLHTSGTTGIPK-IVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPS-VVEI 249
+ ++L+TSG+TG+PK IV ++ +++FD D+ + + + +
Sbjct: 288 MLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVV 347
Query: 250 FLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPT---LLRRFGSQLIKSTVL 306
+ L +GA+ ++ ++ + ++ PT LL ++G +K
Sbjct: 348 YGPLCNGATSVLFESTPVYPNAGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDR 407
Query: 307 SATTSLRVLALGGEAFPSLTVLRSWRGEGN-KTQIFNVYGITEVSSWATIYRIPEKTLNS 365
S SLR L GE R G+ + + + + TE R E+
Sbjct: 408 S---SLRTLGSVGEPINCEAWEWLHRVVGDSRCTLVDTWWQTETGGICIAPRPSEEGAEI 464
Query: 366 TLKCELPVQLGFPLLGTVVEVRDTNGFTIQEG--SGQVFLG----GRNRVCFLDDEVTVP 419
LP P G V + D G ++ SG + + G R + D + V
Sbjct: 465 -----LPAMAMRPFFGIVPVLMDEKGSVVEGSNVSGALCISQAWPGMARTIYGDHQRFVD 519
Query: 420 LGTMRATGDFVT------VKDGEIFFLGRKDSQIKRHGKRLNIELVQQVAEELQQVESCA 473
G + T + G GR D I G RL ++ + V A
Sbjct: 520 AYFKAYPGYYFTGDGAYRTEGGYYQITGRMDDVINISGHRLGTAEIEDAIADHPAVPESA 579
Query: 474 VTWYNQ----EKLILFMVSKD-ASVKEYIFKELQKYLPS----HAVPDELVLIDSLPFTS 524
V Y E F+V KD A + + +EL+ + + +AVPDE++++ LP T
Sbjct: 580 VIGYPHDIKGEAAFAFIVVKDSAGDSDVVVQELKSMVATKIAKYAVPDEILVVKRLPKTR 639
Query: 525 HGKIDVSELNKI 536
GK+ L KI
Sbjct: 640 SGKVMRRLLRKI 651
>gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 42.7 bits (99), Expect = 0.002
Identities = 96/433 (22%), Positives = 161/433 (37%), Gaps = 85/433 (19%)
Query: 27 NQLPVYYTYKTVVNAASELSNFLLLHCDFQGIRE--IGLYCQPGIDLPSWILGILQV--- 81
NQ + +YK V + A L + LLH ++ + +G++ Q + P WI+ L
Sbjct: 100 NQPYRWLSYKQVSDRAEYLGS-CLLHKGYKSSPDQFVGIFAQ---NRPEWIISELACYTY 155
Query: 82 PAAYVPIEPDSPPSLSTHFMKKCNLKYILVEKKQINKFKSFHETLLNYDTFTVEHNDLVL 141
VP+ P H + K ++ ++ + Q K+ FT ++L
Sbjct: 156 SMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQ----KALVLIGNVEKGFTPSLKVIIL 211
Query: 142 FRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKHC---LAYVLHT 198
++ +D K++ EK I+ I S + E +EH + L+ + T
Sbjct: 212 ---------MDPFDDDLKQRGEKSGIE-ILSLYDAENLGKEHFRKPVPPSPEDLSVICFT 261
Query: 199 SGTTGIPKIVRVPHKCIVPNIQHF----RVLFDITQEDVLFLASPLTFDPSVVEIFLALS 254
SGTTG PK + H+ IV N F ++ T +DV PL + + S
Sbjct: 262 SGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYS 321
Query: 255 SGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRRFGSQ------------LIK 302
GA + ++LL + ++ + T+ A P LL R + L+K
Sbjct: 322 CGARVGFFQGDIRLLADDMKTL-----KPTLFPAVPRLLNRIYDKVQNEAKTPLKKFLLK 376
Query: 303 STVLSATTSL-------------------------RVLALGGEAFPSLTVLRSWRGEGNK 337
V S L RV + A P T + ++
Sbjct: 377 LAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMG 436
Query: 338 TQIFNVYGITEVSSWATIYRIPEKTLNSTLKCELPVQLGFPLLGTVV---EVRDTNGFTI 394
Q++ YG TE + T + +P + +G PL V +V D N FT+
Sbjct: 437 CQVYEAYGQTECTGGCT-FTLPGDWTSG--------HVGVPLACNYVKLEDVADMNYFTV 487
Query: 395 QEGSGQVFLGGRN 407
G+V + G N
Sbjct: 488 -NNEGEVCIKGTN 499
>gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 42.7 bits (99), Expect = 0.002
Identities = 96/433 (22%), Positives = 161/433 (37%), Gaps = 85/433 (19%)
Query: 27 NQLPVYYTYKTVVNAASELSNFLLLHCDFQGIRE--IGLYCQPGIDLPSWILGILQV--- 81
NQ + +YK V + A L + LLH ++ + +G++ Q + P WI+ L
Sbjct: 100 NQPYRWLSYKQVSDRAEYLGS-CLLHKGYKSSPDQFVGIFAQ---NRPEWIISELACYTY 155
Query: 82 PAAYVPIEPDSPPSLSTHFMKKCNLKYILVEKKQINKFKSFHETLLNYDTFTVEHNDLVL 141
VP+ P H + K ++ ++ + Q K+ FT ++L
Sbjct: 156 SMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQ----KALVLIGNVEKGFTPSLKVIIL 211
Query: 142 FRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKHC---LAYVLHT 198
++ +D K++ EK I+ I S + E +EH + L+ + T
Sbjct: 212 ---------MDPFDDDLKQRGEKSGIE-ILSLYDAENLGKEHFRKPVPPSPEDLSVICFT 261
Query: 199 SGTTGIPKIVRVPHKCIVPNIQHF----RVLFDITQEDVLFLASPLTFDPSVVEIFLALS 254
SGTTG PK + H+ IV N F ++ T +DV PL + + S
Sbjct: 262 SGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYS 321
Query: 255 SGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRRFGSQ------------LIK 302
GA + ++LL + ++ + T+ A P LL R + L+K
Sbjct: 322 CGARVGFFQGDIRLLADDMKTL-----KPTLFPAVPRLLNRIYDKVQNEAKTPLKKFLLK 376
Query: 303 STVLSATTSL-------------------------RVLALGGEAFPSLTVLRSWRGEGNK 337
V S L RV + A P T + ++
Sbjct: 377 LAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMG 436
Query: 338 TQIFNVYGITEVSSWATIYRIPEKTLNSTLKCELPVQLGFPLLGTVV---EVRDTNGFTI 394
Q++ YG TE + T + +P + +G PL V +V D N FT+
Sbjct: 437 CQVYEAYGQTECTGGCT-FTLPGDWTSG--------HVGVPLACNYVKLEDVADMNYFTV 487
Query: 395 QEGSGQVFLGGRN 407
G+V + G N
Sbjct: 488 -NNEGEVCIKGTN 499
>gi|42794756 acyl-CoA synthetase long-chain family member 5 isoform
a [Homo sapiens]
Length = 739
Score = 42.7 bits (99), Expect = 0.002
Identities = 96/433 (22%), Positives = 161/433 (37%), Gaps = 85/433 (19%)
Query: 27 NQLPVYYTYKTVVNAASELSNFLLLHCDFQGIRE--IGLYCQPGIDLPSWILGILQV--- 81
NQ + +YK V + A L + LLH ++ + +G++ Q + P WI+ L
Sbjct: 156 NQPYRWLSYKQVSDRAEYLGS-CLLHKGYKSSPDQFVGIFAQ---NRPEWIISELACYTY 211
Query: 82 PAAYVPIEPDSPPSLSTHFMKKCNLKYILVEKKQINKFKSFHETLLNYDTFTVEHNDLVL 141
VP+ P H + K ++ ++ + Q K+ FT ++L
Sbjct: 212 SMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQ----KALVLIGNVEKGFTPSLKVIIL 267
Query: 142 FRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKHC---LAYVLHT 198
++ +D K++ EK I+ I S + E +EH + L+ + T
Sbjct: 268 ---------MDPFDDDLKQRGEKSGIE-ILSLYDAENLGKEHFRKPVPPSPEDLSVICFT 317
Query: 199 SGTTGIPKIVRVPHKCIVPNIQHF----RVLFDITQEDVLFLASPLTFDPSVVEIFLALS 254
SGTTG PK + H+ IV N F ++ T +DV PL + + S
Sbjct: 318 SGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYS 377
Query: 255 SGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRRFGSQ------------LIK 302
GA + ++LL + ++ + T+ A P LL R + L+K
Sbjct: 378 CGARVGFFQGDIRLLADDMKTL-----KPTLFPAVPRLLNRIYDKVQNEAKTPLKKFLLK 432
Query: 303 STVLSATTSL-------------------------RVLALGGEAFPSLTVLRSWRGEGNK 337
V S L RV + A P T + ++
Sbjct: 433 LAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMG 492
Query: 338 TQIFNVYGITEVSSWATIYRIPEKTLNSTLKCELPVQLGFPLLGTVV---EVRDTNGFTI 394
Q++ YG TE + T + +P + +G PL V +V D N FT+
Sbjct: 493 CQVYEAYGQTECTGGCT-FTLPGDWTSG--------HVGVPLACNYVKLEDVADMNYFTV 543
Query: 395 QEGSGQVFLGGRN 407
G+V + G N
Sbjct: 544 -NNEGEVCIKGTN 555
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 42.4 bits (98), Expect = 0.002
Identities = 39/139 (28%), Positives = 60/139 (43%), Gaps = 12/139 (8%)
Query: 759 WRSDTGKCVDA----SPLVVIPTFDKSSTTVYIGSHSHRMKAVDFYSGKVKWEQILGDRI 814
W +TGKC + +V +F+ ST V GS K D +G E++ R
Sbjct: 162 WSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNG----EEVYTLRG 217
Query: 815 ESSACVS----KCGNFIVVGCYNGLVYVLKSNSGEKYWMFTTEDAVKSSATMDPTTGLIY 870
S+ +S G+ I+ G ++ V V +++G K + A SSA+ + LI
Sbjct: 218 HSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLIL 277
Query: 871 IGSHDQHAYALDIYRKKCV 889
GS D+ D KCV
Sbjct: 278 TGSMDKTCKLWDATNGKCV 296
>gi|31982927 acetoacetyl-CoA synthetase [Homo sapiens]
Length = 672
Score = 40.8 bits (94), Expect = 0.007
Identities = 79/377 (20%), Positives = 148/377 (39%), Gaps = 49/377 (12%)
Query: 182 EHMDLRLKHCLAYVLHTSGTTGIPK-IVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPL 240
E L H L +++ +SGTTG PK +V ++ +++ + ++T D+L + +
Sbjct: 275 EFEQLPFSHPL-FIMFSSGTTGAPKCMVHSAGGTLIQHLKEHLLHGNMTSSDILLCYTTV 333
Query: 241 TFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRRFGSQL 300
+ + L L++GA++++ S + + L +TVL L +
Sbjct: 334 GWMMWNWMVSL-LATGAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKA 392
Query: 301 IKSTVLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPE 360
+K + L + G + + +R + + ++ G T++ S +
Sbjct: 393 MKPVETHSLQMLHTILSTGSPLKAQSYEYVYRCIKSSILLGSISGGTDIISCFMGHNF-- 450
Query: 361 KTLNSTLKCELPVQLG---FPLLGTVVEVRDTNGFTIQEGSGQVFL-------------- 403
LPV G LG VE + G + SG++
Sbjct: 451 ---------SLPVYKGEIQARNLGMAVEAWNEEGKAVWGESGELVCTKPIPCQPTHFWND 501
Query: 404 --GGRNRVCFLDDEVTVPLGTMRATGDFVTV--KDGEIFFLGRKDSQIKRHGKRLNIELV 459
G + R + + A GD+ + K G I LGR D + +G R +
Sbjct: 502 ENGNKYRKAYFSK-----FPGIWAHGDYCRINPKTGGIVMLGRSDGTLNPNGVRFGSSEI 556
Query: 460 QQVAEELQQVE-SCAVTWYN---QEKLILF--MVSKDA---SVKEYIFKELQKYLPSHAV 510
+ E ++VE S V YN +E++ILF M S A + + I ++ L + V
Sbjct: 557 YNIVESFEEVEDSLCVPQYNKYREERVILFLKMASGHAFQPDLVKRIRDAIRMGLSARHV 616
Query: 511 PDELVLIDSLPFTSHGK 527
P ++ +P+T +GK
Sbjct: 617 PSLILETKGIPYTLNGK 633
>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 2 [Homo sapiens]
Length = 571
Score = 40.4 bits (93), Expect = 0.009
Identities = 108/509 (21%), Positives = 188/509 (36%), Gaps = 84/509 (16%)
Query: 71 LPSW---ILGILQVPAAYVPIEPDSPPSLSTHFMKKCNLKYILVEKKQINKFKSF---HE 124
+P W ILG ++ ++P T MK ++ Y L Q++K K+ E
Sbjct: 116 VPEWWLVILGCIRAGLIFMP---------GTIQMKSTDILYRL----QMSKAKAIVAGDE 162
Query: 125 TLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHM 184
+ DT E L + L V+ DG ++K ++ ++ H E ++E
Sbjct: 163 VIQEVDTVASECPSLRIKLL------VSEKSCDGWLNFKKLLNEASTTHHCVETGSQE-- 214
Query: 185 DLRLKHCLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDP 244
+ + TSGT+G+PK+ + + + + D+++ S +
Sbjct: 215 -------ASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWIL 267
Query: 245 SVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRRFGSQLIKST 304
+++ L + + V K P + L S + + + P + R Q + S
Sbjct: 268 NILGSLLESWTLGACTFVHLLPKFDPLVILKTL-SSYPIKSMMGAPIVYRMLLQQDLSSY 326
Query: 305 VLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPEKTLN 364
L+ GGE+ T L +WR + I YG TE + +
Sbjct: 327 KFP---HLQNCLAGGESLLPET-LENWRAQTG-LDIREFYGQTETGLTCMV--------S 373
Query: 365 STLKCELPVQLGFPLLGTVVEVRDTNGFTIQEGS---GQVFLGGRNRVCFLDDEVTVPLG 421
T+K ++ G+ +GT D GS G + G + F +
Sbjct: 374 KTMK----IKPGY--MGTAASCYDVQVIAFVHGSPRAGDLGFAGTMTLSFCGHQENPDKT 427
Query: 422 TMRATGDF-------VTVKDGEIFFLGRKDSQIKRHGKRLNIELVQQVAEELQQVESCAV 474
GDF + +DG F+GR D I G R+ V+ + V AV
Sbjct: 428 AANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAV 487
Query: 475 TWYNQE------KLILFMVSKDAS-VKEYIFKELQKYLPS----HAVPDELVLIDSLPFT 523
K + + S+ S E + KELQ+++ S + P ++ + +LP T
Sbjct: 488 ISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKT 547
Query: 524 SHGKIDVSELNKIYLNYINLKSENKLSGK 552
GKI ++L E K+SGK
Sbjct: 548 VTGKIQRTKLR---------DKEWKMSGK 567
>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 1 [Homo sapiens]
Length = 571
Score = 40.4 bits (93), Expect = 0.009
Identities = 108/509 (21%), Positives = 188/509 (36%), Gaps = 84/509 (16%)
Query: 71 LPSW---ILGILQVPAAYVPIEPDSPPSLSTHFMKKCNLKYILVEKKQINKFKSF---HE 124
+P W ILG ++ ++P T MK ++ Y L Q++K K+ E
Sbjct: 116 VPEWWLVILGCIRAGLIFMP---------GTIQMKSTDILYRL----QMSKAKAIVAGDE 162
Query: 125 TLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHM 184
+ DT E L + L V+ DG ++K ++ ++ H E ++E
Sbjct: 163 VIQEVDTVASECPSLRIKLL------VSEKSCDGWLNFKKLLNEASTTHHCVETGSQE-- 214
Query: 185 DLRLKHCLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDP 244
+ + TSGT+G+PK+ + + + + D+++ S +
Sbjct: 215 -------ASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWIL 267
Query: 245 SVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRRFGSQLIKST 304
+++ L + + V K P + L S + + + P + R Q + S
Sbjct: 268 NILGSLLESWTLGACTFVHLLPKFDPLVILKTL-SSYPIKSMMGAPIVYRMLLQQDLSSY 326
Query: 305 VLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPEKTLN 364
L+ GGE+ T L +WR + I YG TE + +
Sbjct: 327 KFP---HLQNCLAGGESLLPET-LENWRAQTG-LDIREFYGQTETGLTCMV--------S 373
Query: 365 STLKCELPVQLGFPLLGTVVEVRDTNGFTIQEGS---GQVFLGGRNRVCFLDDEVTVPLG 421
T+K ++ G+ +GT D GS G + G + F +
Sbjct: 374 KTMK----IKPGY--MGTAASCYDVQVIAFVHGSPRAGDLGFAGTMTLSFCGHQENPDKT 427
Query: 422 TMRATGDF-------VTVKDGEIFFLGRKDSQIKRHGKRLNIELVQQVAEELQQVESCAV 474
GDF + +DG F+GR D I G R+ V+ + V AV
Sbjct: 428 AANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAV 487
Query: 475 TWYNQE------KLILFMVSKDAS-VKEYIFKELQKYLPS----HAVPDELVLIDSLPFT 523
K + + S+ S E + KELQ+++ S + P ++ + +LP T
Sbjct: 488 ISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKT 547
Query: 524 SHGKIDVSELNKIYLNYINLKSENKLSGK 552
GKI ++L E K+SGK
Sbjct: 548 VTGKIQRTKLR---------DKEWKMSGK 567
>gi|145312265 endoplasmic reticulum to nucleus signalling 2 [Homo
sapiens]
Length = 974
Score = 39.7 bits (91), Expect = 0.016
Identities = 43/152 (28%), Positives = 64/152 (42%), Gaps = 35/152 (23%)
Query: 802 GKVKWEQILGDRIESSACVSKCGNFIVVGCYNGLVYVLKSNSGEKYWMFTTEDAVKSSAT 861
G +K + + + +S C S G F G +V+ SGE TTE
Sbjct: 148 GLMKLPFTIPELVHASPCRSSDGVFYT-GRKQDAWFVVDPESGETQMTLTTEG------- 199
Query: 862 MDPTTGLIYIGS-------HDQHAYAL---DIYRKKCVWKSKCGGTVFSSPCLNLIP--H 909
P+T +YIG HD A AL YR+ +S+P ++ P +
Sbjct: 200 --PSTPRLYIGRTQYTVTMHDPRAPALRWNTTYRR------------YSAPPMDGSPGKY 245
Query: 910 HLYFATLG-GLLLAVNPATGNVIWKHSCGKPL 940
+ A+ G GLLL V+P +G V+W G P+
Sbjct: 246 MSHLASCGMGLLLTVDPGSGTVLWTQDLGVPV 277
>gi|58331161 PHD finger protein 19 isoform a [Homo sapiens]
Length = 580
Score = 39.7 bits (91), Expect = 0.016
Identities = 61/252 (24%), Positives = 95/252 (37%), Gaps = 44/252 (17%)
Query: 467 QQVESCAVTWYNQEKLILFMVSKDASVKEYIFKELQKYLPSHAVPDELVLIDSLPFTSHG 526
+ +E + W + L L+ + + K + F+E+ ++ H +L + S P T G
Sbjct: 251 EYIERLPLRWVDVVHLALYNLGVQSKKKYFDFEEILAFVNHHWELLQLGKLTSTPVTDRG 310
Query: 527 KIDVSELNKIYLNYINLKSENKLSGKEDLWEKLQYLWKSTL--NLPEDLLRVPDESLFLN 584
LN +N L GKE +K + + + N P LL PD+ L N
Sbjct: 311 --------PHLLNALNSYKSRFLCGKEIKKKKCIFRLRIRVPPNPPGKLL--PDKGLLPN 360
Query: 585 SGGDSLKSIRLLSEIEKLVGTSVPGLLEIILSSSILEIYNH-----ILQTVVPDEDVTFR 639
S SE+ K G S PGLL +Y +L+ +P D T
Sbjct: 361 ENSAS-------SELRKR-GKSKPGLLPHEFQQQKRRVYRRKRSKFLLEDAIPSSDFT-- 410
Query: 640 KSCATKRKLSDINQEEASGTSLHQKAIMTFTCHNEINAFVVLSRGSQILS-LNSTRFLTK 698
A T+ H +I FT +EI + S G S ++ST +
Sbjct: 411 ---------------SAWSTNHHLASIFDFTL-DEIQSLKSASSGQTFFSDVDSTDAAST 454
Query: 699 LGHCSSACPSDS 710
G S++ DS
Sbjct: 455 SGSASTSLSYDS 466
>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
sapiens]
Length = 577
Score = 38.1 bits (87), Expect = 0.046
Identities = 39/130 (30%), Positives = 57/130 (43%), Gaps = 12/130 (9%)
Query: 418 VPLGTMRATGDFVTV-KDGEIFFLGRKDSQIKRHGKRLNIELVQQVAEELQQVESCAVTW 476
V G TGD + ++G I FLGR D I G R+ V+ E V AV
Sbjct: 442 VECGDFYNTGDRGKMDEEGYICFLGRSDDIINASGYRIGPAEVESALVEHPAVAESAVVG 501
Query: 477 ----YNQEKLILFMVSKDASV---KEYIFKELQKYLPS----HAVPDELVLIDSLPFTSH 525
E + F+V + K+ + KELQ+++ S + P ++ + LP T
Sbjct: 502 SPDPIRGEVVKAFIVLTPQFLSHDKDQLTKELQQHVKSVTAPYKYPRKVEFVSELPKTIT 561
Query: 526 GKIDVSELNK 535
GKI+ EL K
Sbjct: 562 GKIERKELRK 571
>gi|153946421 endoplasmic reticulum to nucleus signalling 1 [Homo
sapiens]
Length = 977
Score = 35.8 bits (81), Expect = 0.23
Identities = 31/140 (22%), Positives = 64/140 (45%), Gaps = 6/140 (4%)
Query: 802 GKVKWEQILGDRIESSACVSKCGNFIVVGCYNGLVYVLKSNSGEKYWMFTTEDAVKSSAT 861
G K + + +++S C S G + +G + YV+ +GEK ++ A +
Sbjct: 92 GLTKLPFTIPELVQASPCRSSDG-ILYMGKKQDIWYVIDLLTGEKQQTLSSAFA----DS 146
Query: 862 MDPTTGLIYIGSHDQHAYALDIYRKKCVWKSKCGGTVFSSPCLNLIPHHLYFATLG-GLL 920
+ P+T L+Y+G + D ++ W + S P ++ +F + G GL+
Sbjct: 147 LCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYAASLPEDDVDYKMSHFVSNGDGLV 206
Query: 921 LAVNPATGNVIWKHSCGKPL 940
+ V+ +G+V+W + P+
Sbjct: 207 VTVDSESGDVLWIQNYASPV 226
>gi|13376840 WD repeat domain 61 [Homo sapiens]
Length = 305
Score = 35.4 bits (80), Expect = 0.30
Identities = 29/143 (20%), Positives = 55/143 (38%), Gaps = 5/143 (3%)
Query: 746 PAIGTQKMELHVR-WRSDTGK---CVDASPLVVIP-TFDKSSTTVYIGSHSHRMKAVDFY 800
P + ++ H+R W + GK +DA P+ F S + G+H ++
Sbjct: 77 PIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVE 136
Query: 801 SGKVKWEQILGDRIESSACVSKCGNFIVVGCYNGLVYVLKSNSGEKYWMFTTEDAVKSSA 860
SGK ++ + S S G ++ G +G++ + +G+ S
Sbjct: 137 SGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSL 196
Query: 861 TMDPTTGLIYIGSHDQHAYALDI 883
T P + L+ S D + D+
Sbjct: 197 TFSPDSQLLVTASDDGYIKIYDV 219
>gi|42544134 SA hypertension-associated homolog isoform 2 [Homo
sapiens]
Length = 438
Score = 35.0 bits (79), Expect = 0.39
Identities = 43/174 (24%), Positives = 74/174 (42%), Gaps = 14/174 (8%)
Query: 180 AEEHMDLRLKHC-LAYVLHTSGTTGIPKIVRVPHKCIVPNIQ-HFRVLFDITQEDVLFLA 237
++ H ++ KH + + TSGT+G PK+ H + + R D+T DV++
Sbjct: 216 SDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNT 275
Query: 238 SPLTFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRRFG 297
S + S + + + + P+ + L S + +TV + PT+ R
Sbjct: 276 SDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTSILQTL-SKYPITVFCSAPTVYR--- 331
Query: 298 SQLIKSTVLS-ATTSLRVLALGGEAFPSLTVLRSWRGEGNKT--QIFNVYGITE 348
L+++ + S SL+ GE + V WR NKT I+ YG TE
Sbjct: 332 -MLVQNDITSYKFKSLKHCVSAGEPI-TPDVTEKWR---NKTGLDIYEGYGQTE 380
>gi|27477105 lipidosin [Homo sapiens]
Length = 724
Score = 35.0 bits (79), Expect = 0.39
Identities = 55/267 (20%), Positives = 104/267 (38%), Gaps = 31/267 (11%)
Query: 2 TLQELVHKAASCYMDRVAVCFDECNNQLPVYYTYKTVVNAASELSNFLLLHCDFQGIREI 61
T+ + ++A Y D +A+ F + + Y+ ++ A FL L G+++
Sbjct: 104 TVHRMFYEALDKYGDLIALGFKRQDKWEHISYSQYYLL-ARRAAKGFLKL-----GLKQA 157
Query: 62 GLYCQPGIDLPSWI---LGILQVPAAYVPIEPDSPPSLSTHFMKKCNLKYILVE-KKQIN 117
G + P W +G + I S P + C I+V+ +KQ+
Sbjct: 158 HSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLE 217
Query: 118 KFKSFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNE 177
K + L + + +K N M N Y E+ + +E V E
Sbjct: 218 KILKIWKQLPHLKAVVI-----------YKEPPPNKMAN----VYTMEEFMELGNE-VPE 261
Query: 178 EKAEEHMDLRLKHCLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDI----TQEDV 233
E + +D + + +++TSGTTG PK V + I ++ DI Q++V
Sbjct: 262 EALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIRPAEVQQEV 321
Query: 234 LFLASPLT-FDPSVVEIFLALSSGASL 259
+ PL+ + +++ + GA +
Sbjct: 322 VVSYLPLSHIAAQIYDLWTGIQWGAQV 348
>gi|13375727 acyl-CoA synthetase short-chain family member 3 [Homo
sapiens]
Length = 686
Score = 35.0 bits (79), Expect = 0.39
Identities = 87/390 (22%), Positives = 151/390 (38%), Gaps = 42/390 (10%)
Query: 179 KAEEH--MDLRLKHCLAYVLHTSGTTGIPK-IVRVPHKCIVPNIQHFRVLFDITQEDVLF 235
KA+ H + + +H L Y+L+TSGTTG+PK ++R V ++ + +V +
Sbjct: 279 KAQSHDCVPVLSEHPL-YILYTSGTTGLPKGVIRPTGGYAVMLHWSMSSIYGLQPGEVWW 337
Query: 236 LASPLTF--DPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLL 293
AS L + S + L ++L V + + + H V L PT +
Sbjct: 338 AASDLGWVVGHSYICYGPLLHGNTTVLYEGKPVGTPDAGAYFRVLAEHGVAALFTAPTAI 397
Query: 294 RRF-----GSQLIKSTVLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITE 348
R G+ L K L T + L + GE T+ W + + + + TE
Sbjct: 398 RAIRQQDPGAALGKQYSL---TRFKTLFVAGERCDVETL--EWSKNVFRVPVLDHWWQTE 452
Query: 349 VSSWATIYRIPEKTLNSTLKCELPVQLGFPLLGTVVEVRDTNGFTIQEGS-GQVFLG--- 404
S T + K P Q G + G V + D N ++ G + +
Sbjct: 453 TGSPITASCVGL----GNSKTPPPGQAGKSVPGYNVMILDDNMQKLKARCLGNIVVKLPL 508
Query: 405 --GRNRVCFLDDEVTVPLGTMRATGDFVTV------KDGEIFFLGRKDSQIKRHGKRLNI 456
G + + E L + G + T+ ++G ++ + R D I G R++
Sbjct: 509 PPGAFSGLWKNQEAFKHLYFEKFPGYYDTMDAGYMDEEGYLYVMSRVDDVINVAGHRISA 568
Query: 457 ELVQQVAEELQQVESCAVTWYNQE-----KLILFMVSKDASV-KEYIFKELQKYLPSHAV 510
+++ V CAV L L ++ KD + +E + +E+ K++ +
Sbjct: 569 GAIEESILSHGTVADCAVVGKEDPLKGHVPLALCVLRKDINATEEQVLEEIVKHVRQNIG 628
Query: 511 P----DELVLIDSLPFTSHGKIDVSELNKI 536
P V + LP T GKI S L+ I
Sbjct: 629 PVAAFRNAVFVKQLPKTRSGKIPRSALSAI 658
>gi|6912356 echinoderm microtubule associated protein like 2 [Homo
sapiens]
Length = 649
Score = 35.0 bits (79), Expect = 0.39
Identities = 45/210 (21%), Positives = 78/210 (37%), Gaps = 15/210 (7%)
Query: 806 WEQILGDRIESSACVSKCGNFIVVGCYNGLVYVLKSNSGEKYWMFTTEDAVKSSATMDPT 865
W +I+ D S+ G+ + VG G +L + + + + T + S + P
Sbjct: 413 WSRIIEDPARSAG-FHPSGSVLAVGTVTGRWLLLDTETHDLVAIHTDGNEQISVVSFSPD 471
Query: 866 TGLIYIGSHDQ--HAYALDIYRKKCVWKSKCGGTVFSSPCLNLIPHHLYFATLGG--LLL 921
+ +GSHD + Y +D +K KC G L+ F T G +L
Sbjct: 472 GAYLAVGSHDNLVYVYTVDQGGRKVSRLGKCSGHSSFITHLDWAQDSSCFVTNSGDYEIL 531
Query: 922 AVNPATGNVIWKHSCGKPL-FSSPQCCSQYICIGC-------VDGNLLCFTHFGEQVWQF 973
+PAT I + + +++ C + G D N + +H G+ +
Sbjct: 532 YWDPATCKQITSADAVRNMEWATATCVLGFGVFGIWSEGADGTDINAVARSHDGKLLASA 591
Query: 974 STSGPI--FSSPCTSPSEQKIFFGSHDCFI 1001
G + FS PC P +G H +
Sbjct: 592 DDFGKVHLFSYPCCQPRALSHKYGGHSSHV 621
>gi|57165412 acyl-CoA synthetase long-chain family member 6 isoform
b [Homo sapiens]
Length = 722
Score = 34.7 bits (78), Expect = 0.51
Identities = 64/280 (22%), Positives = 107/280 (38%), Gaps = 43/280 (15%)
Query: 32 YYTYKTVVNAASELSNFLLLH-CDFQGIREIGLYCQPGIDLPSWI---LGILQVPAAYVP 87
+ +Y+ V + A L + LL H C + IG++ Q + P WI L VP
Sbjct: 145 WLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQ---NRPEWIIVELACYTYSMVVVP 201
Query: 88 IEPDSPPSLSTHFMKKCNLKYILVEKKQINKFKSFHETLLNYDTFTVEHNDLVLFRLHWK 147
+ P + + ++ ++V+K Q H VE + +L
Sbjct: 202 LYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEH----------VERKETPGLKL--- 248
Query: 148 NTEVNLMLNDGKEKYEKEKIKS----ISSEHVNEEKAEEHMDLRLK---HCLAYVLHTSG 200
++L D E+ KE+ + I S E+ +E+ + L+ V TSG
Sbjct: 249 -----IILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSG 303
Query: 201 TTGIPKIVRVPHKCIVPNIQHF-----RVLFDITQEDVLFLASPLTFDPSVVEIFLALSS 255
TTG PK + H +V + F +V+F Q+DVL PL V +
Sbjct: 304 TTGNPKGAMLTHGNVVADFSGFLKVTEKVIFP-RQDDVLISFLPLAHMFERVIQSVVYCH 362
Query: 256 GASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRR 295
G + ++LL + ++ T+ P LL R
Sbjct: 363 GGRVGFFQGDIRLLSDDMKALC-----PTIFPVVPRLLNR 397
>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 34.7 bits (78), Expect = 0.51
Identities = 110/510 (21%), Positives = 192/510 (37%), Gaps = 80/510 (15%)
Query: 71 LPSW---ILGILQVPAAYVPIEPDSPPSLSTHFMKKCNLKYILVEKKQINKFKSF---HE 124
+P W ILG ++ ++P T MK ++ Y L Q++K K+ E
Sbjct: 116 VPEWWLVILGCIRAGLIFMP---------GTIQMKSTDILYRL----QMSKAKAIVAGDE 162
Query: 125 TLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHM 184
+ DT E L + L V+ DG ++K ++ ++ H E ++E
Sbjct: 163 VIQEVDTVASECPSLRIKLL------VSEKSCDGWLNFKKLLNEASTTHHCVETGSQE-- 214
Query: 185 DLRLKHCLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDP 244
+ + TSGT+G+PK+ + + + + D+++ S +
Sbjct: 215 -------ASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWIL 267
Query: 245 SVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRRFGSQLIKST 304
+++ L + + V K P + L S + + + P + R Q + S
Sbjct: 268 NILGSLLESWTLGACTFVHLLPKFDPLVILKTL-SSYPIKSMMGAPIVYRMLLQQDLSSY 326
Query: 305 VLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPEKTLN 364
L+ GGE+ T L +WR + I YG TE + +
Sbjct: 327 KFP---HLQNCLAGGESLLPET-LENWRAQTG-LDIREFYGQTETGLTCMV--------S 373
Query: 365 STLKCELPVQLGFPLLGTVVEVRDTNGFTIQEGS-GQVFLGGR--NRVCFLDDEVTVPLG 421
T+K + P +G V+V D G + G+ G + + + + V P
Sbjct: 374 KTMKIK-PGYMGTAASCYDVQVIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDK 432
Query: 422 TM-RATGDF-------VTVKDGEIFFLGRKDSQIKRHGKRLNIELVQQVAEELQQVESCA 473
T GDF + +DG F+GR D I G R+ V+ + V A
Sbjct: 433 TAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETA 492
Query: 474 VTWYNQE------KLILFMVSKDAS-VKEYIFKELQKYLPS----HAVPDELVLIDSLPF 522
V K + + S+ S E + KELQ+++ S + P ++ + +LP
Sbjct: 493 VISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPK 552
Query: 523 TSHGKIDVSELNKIYLNYINLKSENKLSGK 552
T GKI ++L E K+SGK
Sbjct: 553 TVTGKIQRTKLR---------DKEWKMSGK 573
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,787,562
Number of Sequences: 37866
Number of extensions: 1910825
Number of successful extensions: 5020
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 49
Number of HSP's that attempted gapping in prelim test: 4958
Number of HSP's gapped (non-prelim): 85
length of query: 1098
length of database: 18,247,518
effective HSP length: 113
effective length of query: 985
effective length of database: 13,968,660
effective search space: 13759130100
effective search space used: 13759130100
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.