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Search of human proteins with 108936958
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|108936958 WD-repeat protein [Homo sapiens]
(342 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|108936958 WD-repeat protein [Homo sapiens] 724 0.0
gi|58331266 WD repeat domain 59 [Homo sapiens] 54 2e-07
gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens] 51 2e-06
gi|157739942 gemin 5 [Homo sapiens] 48 1e-05
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 47 3e-05
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 47 3e-05
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 47 3e-05
gi|14150171 THO complex 3 [Homo sapiens] 45 7e-05
gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] 44 2e-04
gi|5902034 periodic tryptophan protein 1 [Homo sapiens] 44 3e-04
gi|32189425 WD repeat domain 69 [Homo sapiens] 42 6e-04
gi|48928050 F-box and WD repeat domain containing 11 isoform C [... 42 6e-04
gi|41281564 WD repeat domain 37 [Homo sapiens] 42 6e-04
gi|48928048 F-box and WD repeat domain containing 11 isoform A [... 42 6e-04
gi|48928046 F-box and WD repeat domain containing 11 isoform B [... 42 6e-04
gi|19913367 transducin beta-like 1Y [Homo sapiens] 42 0.001
gi|19913365 transducin beta-like 1Y [Homo sapiens] 42 0.001
gi|15150805 transducin beta-like 1Y [Homo sapiens] 42 0.001
gi|13376840 WD repeat domain 61 [Homo sapiens] 41 0.002
gi|4503513 eukaryotic translation initiation factor 3, subunit 2... 40 0.003
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 40 0.003
gi|4885105 chromatin assembly factor 1 subunit B [Homo sapiens] 40 0.003
gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens] 40 0.004
gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens] 40 0.004
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 40 0.004
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 40 0.004
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 40 0.004
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 40 0.004
gi|55741849 WD repeat domain 22 [Homo sapiens] 39 0.005
gi|113865883 WD repeat domain 38 [Homo sapiens] 39 0.005
>gi|108936958 WD-repeat protein [Homo sapiens]
Length = 342
Score = 724 bits (1870), Expect = 0.0
Identities = 342/342 (100%), Positives = 342/342 (100%)
Query: 1 MSLHGKRKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKVQLVGLDEESSEFI 60
MSLHGKRKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKVQLVGLDEESSEFI
Sbjct: 1 MSLHGKRKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKVQLVGLDEESSEFI 60
Query: 61 CRNTFDHPYPTTKLMWIPDTKGVYPDLLATSGDYLRVWRVGETETRLECLLNNNKNSDFC 120
CRNTFDHPYPTTKLMWIPDTKGVYPDLLATSGDYLRVWRVGETETRLECLLNNNKNSDFC
Sbjct: 61 CRNTFDHPYPTTKLMWIPDTKGVYPDLLATSGDYLRVWRVGETETRLECLLNNNKNSDFC 120
Query: 121 APLTSFDWNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDI 180
APLTSFDWNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDI
Sbjct: 121 APLTSFDWNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDI 180
Query: 181 AFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATM 240
AFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATM
Sbjct: 181 AFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATM 240
Query: 241 AMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMP 300
AMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMP
Sbjct: 241 AMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMP 300
Query: 301 RAIEDPILAYTAEGEINNVQWASTQPDWIAICYNNCLEILRV 342
RAIEDPILAYTAEGEINNVQWASTQPDWIAICYNNCLEILRV
Sbjct: 301 RAIEDPILAYTAEGEINNVQWASTQPDWIAICYNNCLEILRV 342
>gi|58331266 WD repeat domain 59 [Homo sapiens]
Length = 974
Score = 53.9 bits (128), Expect = 2e-07
Identities = 39/136 (28%), Positives = 66/136 (48%), Gaps = 6/136 (4%)
Query: 163 SGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHH 222
SG V T L H + + D+ + A D+ + D + ++D++ T+
Sbjct: 94 SGEVGTTLQGHTRVISDLDW--AVFEPDLLVTSSVDTYIYIWDIKDTRKPTVALSAVAGA 151
Query: 223 PLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHI 282
++ WNK++ N LAT + DG +V I D R P T V L H + ++G+ W P S +
Sbjct: 152 SQVK--WNKKNANCLAT-SHDG-DVRIWDKRKPSTAVEYLAAHLSKIHGLDWHPDSEHIL 207
Query: 283 CTAADDHQALIWDIQQ 298
T++ D+ WD +Q
Sbjct: 208 ATSSQDNSVKFWDYRQ 223
Score = 34.7 bits (78), Expect = 0.13
Identities = 36/134 (26%), Positives = 58/134 (43%), Gaps = 18/134 (13%)
Query: 123 LTSFDWNEVDPYLLGTSSIDTTCTIWGL-ETGQVLGRVNLVSGHVKTQLIAHDKEVYDIA 181
++ DW +P LL TSS+DT IW + +T + ++ V+G +Q+ + K +A
Sbjct: 108 ISDLDWAVFEPDLLVTSSVDTYIYIWDIKDTRKPTVALSAVAG--ASQVKWNKKNANCLA 165
Query: 182 FSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMA 241
S DG VR++D R + + Y + L W+ + LAT +
Sbjct: 166 TSH-------------DGDVRIWDKRK-PSTAVEYLAAHLSKIHGLDWHPDSEHILATSS 211
Query: 242 MDGMEVVILDVRVP 255
D V D R P
Sbjct: 212 QDN-SVKFWDYRQP 224
>gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens]
Length = 446
Score = 50.8 bits (120), Expect = 2e-06
Identities = 48/178 (26%), Positives = 79/178 (44%), Gaps = 23/178 (12%)
Query: 163 SGHVKTQ-LIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQH 221
S HV + + H + V D+ +S +FAS AD S+R++D+R +
Sbjct: 249 SWHVDQRPFVGHTRSVEDLQWSPTEN--TVFASCSADASIRIWDIRAAPSKACMLTTATA 306
Query: 222 HP--LLRLCWNKQDPNYLATMAMDGMEVVILDVRV--PCTPVARLNNHRACVNGIAWAPH 277
H + + W++++P +L + DG + I D+R +PVA H A V + W P
Sbjct: 307 HDGDVNVISWSRREP-FLLSGGDDGA-LKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQ 364
Query: 278 SSCHICTAADDHQALIWD--IQQMPRAIE---DPILA---------YTAEGEINNVQW 321
S + DHQ WD +++ P A + DP LA + E E+ + W
Sbjct: 365 DSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKELHW 422
Score = 34.7 bits (78), Expect = 0.13
Identities = 15/62 (24%), Positives = 27/62 (43%)
Query: 265 HRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWAST 324
H V + W+P + + + D IWDI+ P A +G++N + W+
Sbjct: 260 HTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRR 319
Query: 325 QP 326
+P
Sbjct: 320 EP 321
>gi|157739942 gemin 5 [Homo sapiens]
Length = 1508
Score = 47.8 bits (112), Expect = 1e-05
Identities = 36/150 (24%), Positives = 68/150 (45%), Gaps = 26/150 (17%)
Query: 198 DGSVRMFDLRHLEHSTIIYEDPQHHPLLR-LCWNKQ-----DPNYLATMAMDGMEVVILD 251
DGS+ +F + +L+ +I QHH L+ + W+ + + +YL + + + +
Sbjct: 557 DGSIEIFQIPNLK---LICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHN 613
Query: 252 VRV--------PCT---PVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMP 300
++ P T P L+ H A + +AW+PH + +A+ D A +WD +
Sbjct: 614 LKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALR-- 671
Query: 301 RAIEDPILAYTA-EGEINNVQWASTQPDWI 329
E+P+ + G + V W+ PD I
Sbjct: 672 ---EEPLCNFRGHRGRLLCVAWSPLDPDCI 698
Score = 33.5 bits (75), Expect = 0.28
Identities = 35/151 (23%), Positives = 57/151 (37%), Gaps = 47/151 (31%)
Query: 169 QLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQH-HPLLRL 227
+L+ H + V FS G ++ A+ DG+V+++D+ E T++ E H H + L
Sbjct: 59 ELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDV---ETKTVVTEHALHQHTISTL 115
Query: 228 CW----------------------NKQDPNYL--------------------ATMAMDGM 245
W N+ D +L A DG+
Sbjct: 116 HWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGI 175
Query: 246 EVVILDVRVPCTPVARLNNHRACVNGIAWAP 276
VVI+D+ + RL H ++ IAW P
Sbjct: 176 -VVIIDISKKGEVIHRLRGHDDEIHSIAWCP 205
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 46.6 bits (109), Expect = 3e-05
Identities = 18/46 (39%), Positives = 28/46 (60%)
Query: 256 CTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPR 301
C P RL H+ G++W P+ S H+ +A+DDH +WDI +P+
Sbjct: 132 CNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPK 177
Score = 45.8 bits (107), Expect = 6e-05
Identities = 52/217 (23%), Positives = 90/217 (41%), Gaps = 22/217 (10%)
Query: 128 WN-EVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAG 186
WN + +LL S T C +W + G+V KT H V D+++
Sbjct: 150 WNPNLSGHLLSASDDHTIC-LWDISAVPKEGKVV----DAKTIFTGHTAVVEDVSWHLLH 204
Query: 187 GGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLR-LCWNKQDPNYLATMAMDGM 245
+F SV D + ++D R S + H + L +N LAT + D
Sbjct: 205 --ESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSAD-K 261
Query: 246 EVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDI-----QQMP 300
V + D+R + +H+ + + W+PH+ + ++ D + +WD+ +Q P
Sbjct: 262 TVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSP 321
Query: 301 RAIED--PILAYTAEG---EINNVQWASTQPDWIAIC 332
ED P L + G +I++ W +P W+ IC
Sbjct: 322 EDAEDGPPELLFIHGGHTAKISDFSWNPNEP-WV-IC 356
Score = 41.2 bits (95), Expect = 0.001
Identities = 51/255 (20%), Positives = 101/255 (39%), Gaps = 27/255 (10%)
Query: 74 LMWIPDTKGVYPDLLATSGDY-LRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVD 132
L W P+ G LL+ S D+ + +W + + + + A + W+ +
Sbjct: 148 LSWNPNLSG---HLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLH 204
Query: 133 PYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMF 192
L G+ + D IW + + V AH EV ++F+ +
Sbjct: 205 ESLFGSVADDQKLMIWDTRSNNTSKPSHSVD--------AHTAEVNCLSFNPYS--EFIL 254
Query: 193 ASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMD--------- 243
A+ AD +V ++DLR+L+ +E + + ++ W+ + LA+ D
Sbjct: 255 ATGSADKTVALWDLRNLKLKLHSFESHKDE-IFQVQWSPHNETILASSGTDRRLNVWDLS 313
Query: 244 --GMEVVILDVRVPCTPVARLNN-HRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMP 300
G E D + ++ H A ++ +W P+ IC+ ++D+ +W + +
Sbjct: 314 KIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENI 373
Query: 301 RAIEDPILAYTAEGE 315
EDP + EG+
Sbjct: 374 YNDEDPEGSVDPEGQ 388
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 46.6 bits (109), Expect = 3e-05
Identities = 18/46 (39%), Positives = 28/46 (60%)
Query: 256 CTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPR 301
C P RL H+ G++W P+ S H+ +A+DDH +WDI +P+
Sbjct: 166 CNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPK 211
Score = 45.8 bits (107), Expect = 6e-05
Identities = 52/217 (23%), Positives = 90/217 (41%), Gaps = 22/217 (10%)
Query: 128 WN-EVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAG 186
WN + +LL S T C +W + G+V KT H V D+++
Sbjct: 184 WNPNLSGHLLSASDDHTIC-LWDISAVPKEGKVV----DAKTIFTGHTAVVEDVSWHLLH 238
Query: 187 GGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLR-LCWNKQDPNYLATMAMDGM 245
+F SV D + ++D R S + H + L +N LAT + D
Sbjct: 239 --ESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSAD-K 295
Query: 246 EVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDI-----QQMP 300
V + D+R + +H+ + + W+PH+ + ++ D + +WD+ +Q P
Sbjct: 296 TVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSP 355
Query: 301 RAIED--PILAYTAEG---EINNVQWASTQPDWIAIC 332
ED P L + G +I++ W +P W+ IC
Sbjct: 356 EDAEDGPPELLFIHGGHTAKISDFSWNPNEP-WV-IC 390
Score = 41.2 bits (95), Expect = 0.001
Identities = 51/255 (20%), Positives = 101/255 (39%), Gaps = 27/255 (10%)
Query: 74 LMWIPDTKGVYPDLLATSGDY-LRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVD 132
L W P+ G LL+ S D+ + +W + + + + A + W+ +
Sbjct: 182 LSWNPNLSG---HLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLH 238
Query: 133 PYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMF 192
L G+ + D IW + + V AH EV ++F+ +
Sbjct: 239 ESLFGSVADDQKLMIWDTRSNNTSKPSHSVD--------AHTAEVNCLSFNPYS--EFIL 288
Query: 193 ASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMD--------- 243
A+ AD +V ++DLR+L+ +E + + ++ W+ + LA+ D
Sbjct: 289 ATGSADKTVALWDLRNLKLKLHSFESHKDE-IFQVQWSPHNETILASSGTDRRLNVWDLS 347
Query: 244 --GMEVVILDVRVPCTPVARLNN-HRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMP 300
G E D + ++ H A ++ +W P+ IC+ ++D+ +W + +
Sbjct: 348 KIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENI 407
Query: 301 RAIEDPILAYTAEGE 315
EDP + EG+
Sbjct: 408 YNDEDPEGSVDPEGQ 422
>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
sapiens]
Length = 425
Score = 46.6 bits (109), Expect = 3e-05
Identities = 18/46 (39%), Positives = 28/46 (60%)
Query: 256 CTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPR 301
C P RL H+ G++W P+ S H+ +A+DDH +WDI +P+
Sbjct: 167 CNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPK 212
Score = 45.8 bits (107), Expect = 6e-05
Identities = 52/217 (23%), Positives = 90/217 (41%), Gaps = 22/217 (10%)
Query: 128 WN-EVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAG 186
WN + +LL S T C +W + G+V KT H V D+++
Sbjct: 185 WNPNLSGHLLSASDDHTIC-LWDISAVPKEGKVV----DAKTIFTGHTAVVEDVSWHLLH 239
Query: 187 GGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLR-LCWNKQDPNYLATMAMDGM 245
+F SV D + ++D R S + H + L +N LAT + D
Sbjct: 240 --ESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSAD-K 296
Query: 246 EVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDI-----QQMP 300
V + D+R + +H+ + + W+PH+ + ++ D + +WD+ +Q P
Sbjct: 297 TVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSP 356
Query: 301 RAIED--PILAYTAEG---EINNVQWASTQPDWIAIC 332
ED P L + G +I++ W +P W+ IC
Sbjct: 357 EDAEDGPPELLFIHGGHTAKISDFSWNPNEP-WV-IC 391
Score = 41.2 bits (95), Expect = 0.001
Identities = 51/255 (20%), Positives = 101/255 (39%), Gaps = 27/255 (10%)
Query: 74 LMWIPDTKGVYPDLLATSGDY-LRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVD 132
L W P+ G LL+ S D+ + +W + + + + A + W+ +
Sbjct: 183 LSWNPNLSG---HLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLH 239
Query: 133 PYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMF 192
L G+ + D IW + + V AH EV ++F+ +
Sbjct: 240 ESLFGSVADDQKLMIWDTRSNNTSKPSHSVD--------AHTAEVNCLSFNPYS--EFIL 289
Query: 193 ASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMD--------- 243
A+ AD +V ++DLR+L+ +E + + ++ W+ + LA+ D
Sbjct: 290 ATGSADKTVALWDLRNLKLKLHSFESHKDE-IFQVQWSPHNETILASSGTDRRLNVWDLS 348
Query: 244 --GMEVVILDVRVPCTPVARLNN-HRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMP 300
G E D + ++ H A ++ +W P+ IC+ ++D+ +W + +
Sbjct: 349 KIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENI 408
Query: 301 RAIEDPILAYTAEGE 315
EDP + EG+
Sbjct: 409 YNDEDPEGSVDPEGQ 423
>gi|14150171 THO complex 3 [Homo sapiens]
Length = 351
Score = 45.4 bits (106), Expect = 7e-05
Identities = 52/208 (25%), Positives = 85/208 (40%), Gaps = 19/208 (9%)
Query: 137 GTSSIDTTCTIWGLETGQVLGRVNLVSGHVKT-QLIAHDKEVYDIAFSRAGGGRDMFASV 195
G S+ C++ + VLG L GH KT + +AH +V+ +A+S G AS
Sbjct: 17 GPGSMAPWCSVSSGPSRYVLGMQELFRGHSKTREFLAHSAKVHSVAWSCDG---RRLASG 73
Query: 196 GADGSVRMFDLRHLEHSTIIYEDPQH---HPLLRLCWNKQDPNYLATMAMDGMEVVILDV 252
D + +F LE ++ E+ + +LCW+ +P+ T + D + I DV
Sbjct: 74 SFDKTASVF---LLEKDRLVKENNYRGHGDSVDQLCWHPSNPDLFVTASGD-KTIRIWDV 129
Query: 253 RVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTA 312
R +A +N +N I W+P DD I +A E
Sbjct: 130 RT-TKCIATVNTKGENIN-ICWSPDGQTIAVGNKDDVVTFIDAKTHRSKAEEQ------F 181
Query: 313 EGEINNVQWASTQPDWIAICYNNCLEIL 340
+ E+N + W + + N C+ IL
Sbjct: 182 KFEVNEISWNNDNNMFFLTNGNGCINIL 209
>gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]
Length = 425
Score = 44.3 bits (103), Expect = 2e-04
Identities = 50/226 (22%), Positives = 96/226 (42%), Gaps = 23/226 (10%)
Query: 128 WNE-VDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAG 186
WN + +LL S T C +W + G G++ K H V D+A+
Sbjct: 184 WNSNLSGHLLSASDDHTVC-LWDINAGPKEGKIV----DAKAIFTGHSAVVEDVAWHLLH 238
Query: 187 GGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLR-LCWNKQDPNYLATMAMDGM 245
+F SV D + ++D R S + H + L +N LAT + D
Sbjct: 239 --ESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSAD-K 295
Query: 246 EVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQM--PRAI 303
V + D+R + +H+ + + W+PH+ + ++ D + +WD+ ++ ++
Sbjct: 296 TVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSA 355
Query: 304 ED-----PILAYTAEG---EINNVQWASTQPDWI--AICYNNCLEI 339
ED P L + G +I++ W +P W+ ++ +N ++I
Sbjct: 356 EDAEDGPPELLFIHGGHTAKISDFSWNPNEP-WVICSVSEDNIMQI 400
Score = 43.1 bits (100), Expect = 4e-04
Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 11/101 (10%)
Query: 232 QDPNYLATMAMDGMEVVILDVRVP--------CTPVARLNNHRACVNGIAWAPHSSCHIC 283
Q+P+ +AT +V + P C P RL H+ G++W + S H+
Sbjct: 134 QNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLL 193
Query: 284 TAADDHQALIWDIQQMPR--AIEDPILAYTAEGE-INNVQW 321
+A+DDH +WDI P+ I D +T + +V W
Sbjct: 194 SASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAW 234
Score = 37.0 bits (84), Expect = 0.026
Identities = 38/183 (20%), Positives = 75/183 (40%), Gaps = 23/183 (12%)
Query: 128 WNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGG 187
W+ + L G+ + D IW + +LV AH EV ++F+
Sbjct: 234 WHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVD--------AHTAEVNCLSFNPYS- 284
Query: 188 GRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMD---- 243
+ A+ AD +V ++DLR+L+ +E + + ++ W+ + LA+ D
Sbjct: 285 -EFILATGSADKTVALWDLRNLKLKLHTFESHKDE-IFQVHWSPHNETILASSGTDRRLN 342
Query: 244 -------GMEVVILDVRVPCTPVARLNN-HRACVNGIAWAPHSSCHICTAADDHQALIWD 295
G E D + ++ H A ++ +W P+ IC+ ++D+ IW
Sbjct: 343 VWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQ 402
Query: 296 IQQ 298
+ +
Sbjct: 403 MAE 405
>gi|5902034 periodic tryptophan protein 1 [Homo sapiens]
Length = 501
Score = 43.5 bits (101), Expect = 3e-04
Identities = 42/169 (24%), Positives = 70/169 (41%), Gaps = 17/169 (10%)
Query: 128 WNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGG 187
WN++ +L ++S D T +W + G+ + + + V+T L H E +
Sbjct: 264 WNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQT-LQFHPFEAQTL------- 315
Query: 188 GRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEV 247
S D SV ++D R + S ++ + R+ WN P + DG V
Sbjct: 316 -----ISGSYDKSVALYDCRSPDESHRMWRFSGQ--IERVTWNHFSPCHFLASTDDGF-V 367
Query: 248 VILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDI 296
LD R P+ LN H ++G+ + + TA+ D IWDI
Sbjct: 368 YNLDARSD-KPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDI 415
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 42.4 bits (98), Expect = 6e-04
Identities = 42/180 (23%), Positives = 64/180 (35%), Gaps = 67/180 (37%)
Query: 120 CAPLTS--FDWNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEV 177
CA ++S F+W D L+ T S+D TC +W G+ + L HD E+
Sbjct: 261 CAEISSASFNW---DCSLILTGSMDKTCKLWDATNGKCV-----------ATLTGHDDEI 306
Query: 178 YDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYL 237
D F G + A+ ADG+ R+F R C
Sbjct: 307 LDSCFDYTG---KLIATASADGTARIFS-----------------AATRKC--------- 337
Query: 238 ATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQ 297
+A+L H ++ I++ P + H+ T + D A IWD Q
Sbjct: 338 ---------------------IAKLEGHEGEISKISFNPQGN-HLLTGSSDKTARIWDAQ 375
Score = 34.3 bits (77), Expect = 0.17
Identities = 51/201 (25%), Positives = 83/201 (41%), Gaps = 33/201 (16%)
Query: 106 RLECLLNNNKNSDF---------CAPLTSFDWNEVDPYLLGTSSIDTTCTIWGLETGQVL 156
RL+ L N N F PLT+ N+ + T S D TC +W +G+ L
Sbjct: 69 RLQEKLGQNSNHTFYLFKVLKAHILPLTNVALNKSGSCFI-TGSYDRTCKLWDTASGEEL 127
Query: 157 GRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIY 216
N + GH VY IAF+ G D A+ D + +++ + + Y
Sbjct: 128 ---NTLEGHRNV--------VYAIAFNNPYG--DKIATGSFDKTCKLWSV----ETGKCY 170
Query: 217 EDPQHH--PLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAW 274
+ H ++ L +N Q +AT +MD + D++ V L H A + +++
Sbjct: 171 HTFRGHTAEIVCLSFNPQS-TLVATGSMD-TTAKLWDIQ-NGEEVYTLRGHSAEIISLSF 227
Query: 275 APHSSCHICTAADDHQALIWD 295
S I T + DH ++WD
Sbjct: 228 NT-SGDRIITGSFDHTVVVWD 247
>gi|48928050 F-box and WD repeat domain containing 11 isoform C
[Homo sapiens]
Length = 542
Score = 42.4 bits (98), Expect = 6e-04
Identities = 53/228 (23%), Positives = 91/228 (39%), Gaps = 44/228 (19%)
Query: 79 DTKGVY----PDLLATSG---DYLRVWRVGETETRLECL--LNNNKNSDFCAPLTSFDWN 129
++KGVY D SG + +++W +T LECL L + S C
Sbjct: 239 NSKGVYCLQYDDEKIISGLRDNSIKIW----DKTSLECLKVLTGHTGSVLCL-------- 286
Query: 130 EVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGR 189
+ D ++ T S D+T +W + TG+VL LI H++ V + FS
Sbjct: 287 QYDERVIVTGSSDSTVRVWDVNTGEVL-----------NTLIHHNEAVLHLRFSNG---- 331
Query: 190 DMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVI 249
+ + D S+ ++D+ T+ H R N D + ++ G +
Sbjct: 332 -LMVTCSKDRSIAVWDMASATDITLRRVLVGH----RAAVNVVDFDDKYIVSASGDRTIK 386
Query: 250 LDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQ 297
+ C V LN H+ GIA + + + + D+ +WDI+
Sbjct: 387 VWSTSTCEFVRTLNGHK---RGIACLQYRDRLVVSGSSDNTIRLWDIE 431
>gi|41281564 WD repeat domain 37 [Homo sapiens]
Length = 494
Score = 42.4 bits (98), Expect = 6e-04
Identities = 41/166 (24%), Positives = 69/166 (41%), Gaps = 21/166 (12%)
Query: 135 LLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFAS 194
L+ TSS DTT +W + VN+ GH T A V+ + D S
Sbjct: 337 LVVTSSRDTTFRLWDFRDPSIHS-VNVFQGHTDTVTSA----VFTVG--------DNVVS 383
Query: 195 VGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILD--- 251
D +V+++DL+++ + +C ++ + + D +V + D
Sbjct: 384 GSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQK----IIALPHDNRQVRLFDMSG 439
Query: 252 VRVPCTPVARLNNHRACVNGIAWAP-HSSCHICTAADDHQALIWDI 296
VR+ P + HR V AW+ H C++ T D QA+ W+I
Sbjct: 440 VRLARLPRSSRQGHRRMVCCSAWSEDHPVCNLFTCGFDRQAIGWNI 485
Score = 35.0 bits (79), Expect = 0.097
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 7/48 (14%)
Query: 130 EVDPYLLGTSSIDTTCTIWGLETGQVL-------GRVNLVSGHVKTQL 170
+ P +LGT+S D T +W +ETG+ L G VN + H QL
Sbjct: 166 KTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL 213
>gi|48928048 F-box and WD repeat domain containing 11 isoform A
[Homo sapiens]
Length = 508
Score = 42.4 bits (98), Expect = 6e-04
Identities = 53/228 (23%), Positives = 91/228 (39%), Gaps = 44/228 (19%)
Query: 79 DTKGVY----PDLLATSG---DYLRVWRVGETETRLECL--LNNNKNSDFCAPLTSFDWN 129
++KGVY D SG + +++W +T LECL L + S C
Sbjct: 205 NSKGVYCLQYDDEKIISGLRDNSIKIW----DKTSLECLKVLTGHTGSVLCL-------- 252
Query: 130 EVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGR 189
+ D ++ T S D+T +W + TG+VL LI H++ V + FS
Sbjct: 253 QYDERVIVTGSSDSTVRVWDVNTGEVL-----------NTLIHHNEAVLHLRFSNG---- 297
Query: 190 DMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVI 249
+ + D S+ ++D+ T+ H R N D + ++ G +
Sbjct: 298 -LMVTCSKDRSIAVWDMASATDITLRRVLVGH----RAAVNVVDFDDKYIVSASGDRTIK 352
Query: 250 LDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQ 297
+ C V LN H+ GIA + + + + D+ +WDI+
Sbjct: 353 VWSTSTCEFVRTLNGHK---RGIACLQYRDRLVVSGSSDNTIRLWDIE 397
>gi|48928046 F-box and WD repeat domain containing 11 isoform B
[Homo sapiens]
Length = 529
Score = 42.4 bits (98), Expect = 6e-04
Identities = 53/228 (23%), Positives = 91/228 (39%), Gaps = 44/228 (19%)
Query: 79 DTKGVY----PDLLATSG---DYLRVWRVGETETRLECL--LNNNKNSDFCAPLTSFDWN 129
++KGVY D SG + +++W +T LECL L + S C
Sbjct: 226 NSKGVYCLQYDDEKIISGLRDNSIKIW----DKTSLECLKVLTGHTGSVLCL-------- 273
Query: 130 EVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGR 189
+ D ++ T S D+T +W + TG+VL LI H++ V + FS
Sbjct: 274 QYDERVIVTGSSDSTVRVWDVNTGEVL-----------NTLIHHNEAVLHLRFSNG---- 318
Query: 190 DMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVI 249
+ + D S+ ++D+ T+ H R N D + ++ G +
Sbjct: 319 -LMVTCSKDRSIAVWDMASATDITLRRVLVGH----RAAVNVVDFDDKYIVSASGDRTIK 373
Query: 250 LDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQ 297
+ C V LN H+ GIA + + + + D+ +WDI+
Sbjct: 374 VWSTSTCEFVRTLNGHK---RGIACLQYRDRLVVSGSSDNTIRLWDIE 418
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 41.6 bits (96), Expect = 0.001
Identities = 59/242 (24%), Positives = 92/242 (38%), Gaps = 57/242 (23%)
Query: 128 WNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQ---LIAHDKEVYDIAFSR 184
WN V LL + S D+T IW L G LV H + + +K+V + ++
Sbjct: 187 WNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNS 245
Query: 185 AGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHH-PLLRLCWNKQDPNYLATMAMD 243
G + A DG R++ E+ + QH P+ L WNK+ NY+ + +D
Sbjct: 246 DG---TLLAMGSYDGFARIW----TENGNLASTLGQHKGPIFALKWNKKG-NYVLSAGVD 297
Query: 244 GMEVV------------------ILDV--------------------RVPCT-PVARLNN 264
++ LDV R+ C PV
Sbjct: 298 KTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQG 357
Query: 265 HRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWAST 324
H VN I W P S + + +DD IW ++Q A + A++ EI ++W+ T
Sbjct: 358 HTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQ--DACVHDLQAHSK--EIYTIKWSPT 412
Query: 325 QP 326
P
Sbjct: 413 GP 414
Score = 38.1 bits (87), Expect = 0.011
Identities = 49/229 (21%), Positives = 91/229 (39%), Gaps = 49/229 (21%)
Query: 42 EYNNKVQLVGLDEESSEFICRNTFDHPYPTTK--------LMWIPDTKGVYPDLLATSGD 93
++ N + + +CR DHP T + + W P LLA+ D
Sbjct: 325 DWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGM-----LLASCSD 379
Query: 94 --YLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDP--------YLLGTSSIDT 143
L++W + + C+ + +S + + W+ P +L ++S D+
Sbjct: 380 DMTLKIWSMKQDA----CVHDLQAHSK---EIYTIKWSPTGPATSNPNSSIMLASASFDS 432
Query: 144 TCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRM 203
T +W +E G V H L+ H + VY +AFS G AS D V +
Sbjct: 433 TVRLWDVEQG--------VCTHT---LMKHQEPVYSVAFSPDG---KYLASGSFDKYVHI 478
Query: 204 FDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDV 252
+ + + ++++ + +CWN + + + A DG V +LD+
Sbjct: 479 W---NTQSGSLVHSYQGTGGIFEVCWNARG-DKVGASASDG-SVCVLDL 522
Score = 35.4 bits (80), Expect = 0.074
Identities = 51/226 (22%), Positives = 76/226 (33%), Gaps = 48/226 (21%)
Query: 88 LATSGDYLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSIDTTCTI 147
L G Y R+ L L +K P+ + WN+ Y+L ++ +D T I
Sbjct: 249 LLAMGSYDGFARIWTENGNLASTLGQHKG-----PIFALKWNKKGNYVL-SAGVDKTTII 302
Query: 148 WGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSR----AGGGRDMFASV---GADGS 200
W TG+ K Q H D+ + A DM V G D
Sbjct: 303 WDAHTGEA-----------KQQFPFHSAPALDVDWQNNMTFASCSTDMCIHVCRLGCDHP 351
Query: 201 VRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVA 260
V+ F H I DP L D M + I ++ V
Sbjct: 352 VKTFQ-GHTNEVNAIKWDPS--------------GMLLASCSDDMTLKIWSMKQDAC-VH 395
Query: 261 RLNNHRACVNGIAWAP--------HSSCHICTAADDHQALIWDIQQ 298
L H + I W+P +SS + +A+ D +WD++Q
Sbjct: 396 DLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQ 441
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 41.6 bits (96), Expect = 0.001
Identities = 59/242 (24%), Positives = 92/242 (38%), Gaps = 57/242 (23%)
Query: 128 WNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQ---LIAHDKEVYDIAFSR 184
WN V LL + S D+T IW L G LV H + + +K+V + ++
Sbjct: 187 WNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNS 245
Query: 185 AGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHH-PLLRLCWNKQDPNYLATMAMD 243
G + A DG R++ E+ + QH P+ L WNK+ NY+ + +D
Sbjct: 246 DG---TLLAMGSYDGFARIW----TENGNLASTLGQHKGPIFALKWNKKG-NYVLSAGVD 297
Query: 244 GMEVV------------------ILDV--------------------RVPCT-PVARLNN 264
++ LDV R+ C PV
Sbjct: 298 KTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQG 357
Query: 265 HRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWAST 324
H VN I W P S + + +DD IW ++Q A + A++ EI ++W+ T
Sbjct: 358 HTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQ--DACVHDLQAHSK--EIYTIKWSPT 412
Query: 325 QP 326
P
Sbjct: 413 GP 414
Score = 38.1 bits (87), Expect = 0.011
Identities = 49/229 (21%), Positives = 91/229 (39%), Gaps = 49/229 (21%)
Query: 42 EYNNKVQLVGLDEESSEFICRNTFDHPYPTTK--------LMWIPDTKGVYPDLLATSGD 93
++ N + + +CR DHP T + + W P LLA+ D
Sbjct: 325 DWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGM-----LLASCSD 379
Query: 94 --YLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDP--------YLLGTSSIDT 143
L++W + + C+ + +S + + W+ P +L ++S D+
Sbjct: 380 DMTLKIWSMKQDA----CVHDLQAHSK---EIYTIKWSPTGPATSNPNSSIMLASASFDS 432
Query: 144 TCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRM 203
T +W +E G V H L+ H + VY +AFS G AS D V +
Sbjct: 433 TVRLWDVEQG--------VCTHT---LMKHQEPVYSVAFSPDG---KYLASGSFDKYVHI 478
Query: 204 FDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDV 252
+ + + ++++ + +CWN + + + A DG V +LD+
Sbjct: 479 W---NTQSGSLVHSYQGTGGIFEVCWNARG-DKVGASASDG-SVCVLDL 522
Score = 35.4 bits (80), Expect = 0.074
Identities = 51/226 (22%), Positives = 76/226 (33%), Gaps = 48/226 (21%)
Query: 88 LATSGDYLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSIDTTCTI 147
L G Y R+ L L +K P+ + WN+ Y+L ++ +D T I
Sbjct: 249 LLAMGSYDGFARIWTENGNLASTLGQHKG-----PIFALKWNKKGNYVL-SAGVDKTTII 302
Query: 148 WGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSR----AGGGRDMFASV---GADGS 200
W TG+ K Q H D+ + A DM V G D
Sbjct: 303 WDAHTGEA-----------KQQFPFHSAPALDVDWQNNMTFASCSTDMCIHVCRLGCDHP 351
Query: 201 VRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVA 260
V+ F H I DP L D M + I ++ V
Sbjct: 352 VKTFQ-GHTNEVNAIKWDPS--------------GMLLASCSDDMTLKIWSMKQDAC-VH 395
Query: 261 RLNNHRACVNGIAWAP--------HSSCHICTAADDHQALIWDIQQ 298
L H + I W+P +SS + +A+ D +WD++Q
Sbjct: 396 DLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQ 441
>gi|15150805 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 41.6 bits (96), Expect = 0.001
Identities = 59/242 (24%), Positives = 92/242 (38%), Gaps = 57/242 (23%)
Query: 128 WNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQ---LIAHDKEVYDIAFSR 184
WN V LL + S D+T IW L G LV H + + +K+V + ++
Sbjct: 187 WNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNS 245
Query: 185 AGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHH-PLLRLCWNKQDPNYLATMAMD 243
G + A DG R++ E+ + QH P+ L WNK+ NY+ + +D
Sbjct: 246 DG---TLLAMGSYDGFARIW----TENGNLASTLGQHKGPIFALKWNKKG-NYVLSAGVD 297
Query: 244 GMEVV------------------ILDV--------------------RVPCT-PVARLNN 264
++ LDV R+ C PV
Sbjct: 298 KTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQG 357
Query: 265 HRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWAST 324
H VN I W P S + + +DD IW ++Q A + A++ EI ++W+ T
Sbjct: 358 HTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQ--DACVHDLQAHSK--EIYTIKWSPT 412
Query: 325 QP 326
P
Sbjct: 413 GP 414
Score = 38.1 bits (87), Expect = 0.011
Identities = 49/229 (21%), Positives = 91/229 (39%), Gaps = 49/229 (21%)
Query: 42 EYNNKVQLVGLDEESSEFICRNTFDHPYPTTK--------LMWIPDTKGVYPDLLATSGD 93
++ N + + +CR DHP T + + W P LLA+ D
Sbjct: 325 DWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGM-----LLASCSD 379
Query: 94 --YLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDP--------YLLGTSSIDT 143
L++W + + C+ + +S + + W+ P +L ++S D+
Sbjct: 380 DMTLKIWSMKQDA----CVHDLQAHSK---EIYTIKWSPTGPATSNPNSSIMLASASFDS 432
Query: 144 TCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRM 203
T +W +E G V H L+ H + VY +AFS G AS D V +
Sbjct: 433 TVRLWDVEQG--------VCTHT---LMKHQEPVYSVAFSPDG---KYLASGSFDKYVHI 478
Query: 204 FDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDV 252
+ + + ++++ + +CWN + + + A DG V +LD+
Sbjct: 479 W---NTQSGSLVHSYQGTGGIFEVCWNARG-DKVGASASDG-SVCVLDL 522
Score = 35.4 bits (80), Expect = 0.074
Identities = 51/226 (22%), Positives = 76/226 (33%), Gaps = 48/226 (21%)
Query: 88 LATSGDYLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSIDTTCTI 147
L G Y R+ L L +K P+ + WN+ Y+L ++ +D T I
Sbjct: 249 LLAMGSYDGFARIWTENGNLASTLGQHKG-----PIFALKWNKKGNYVL-SAGVDKTTII 302
Query: 148 WGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSR----AGGGRDMFASV---GADGS 200
W TG+ K Q H D+ + A DM V G D
Sbjct: 303 WDAHTGEA-----------KQQFPFHSAPALDVDWQNNMTFASCSTDMCIHVCRLGCDHP 351
Query: 201 VRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVA 260
V+ F H I DP L D M + I ++ V
Sbjct: 352 VKTFQ-GHTNEVNAIKWDPS--------------GMLLASCSDDMTLKIWSMKQDAC-VH 395
Query: 261 RLNNHRACVNGIAWAP--------HSSCHICTAADDHQALIWDIQQ 298
L H + I W+P +SS + +A+ D +WD++Q
Sbjct: 396 DLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQ 441
>gi|13376840 WD repeat domain 61 [Homo sapiens]
Length = 305
Score = 40.8 bits (94), Expect = 0.002
Identities = 52/235 (22%), Positives = 91/235 (38%), Gaps = 46/235 (19%)
Query: 93 DYLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSIDTTCTIWGLE- 151
D ++VW+ + L+ L ++ + S D + P + +SS+D +W LE
Sbjct: 42 DLVKVWKWRDERLDLQWSLEGHQLG-----VVSVDISHTLP-IAASSSLDAHIRLWDLEN 95
Query: 152 ---------------------------TGQVLGRVNLV---SGHVKTQLIAHDKEVYDIA 181
TG +G+VN+ SG + L K + IA
Sbjct: 96 GKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIA 155
Query: 182 FSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMA 241
+S G AS DG + +FD + +++ H +R D L T +
Sbjct: 156 YSPDG---KYLASGAIDGIINIFD---IATGKLLHTLEGHAMPIRSLTFSPDSQLLVTAS 209
Query: 242 MDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDI 296
DG + I DV+ L+ H + V +A+ P + H +++ D +WD+
Sbjct: 210 DDGY-IKIYDVQ-HANLAGTLSGHASWVLNVAFCPDDT-HFVSSSSDKSVKVWDV 261
>gi|4503513 eukaryotic translation initiation factor 3, subunit 2
beta, 36kDa [Homo sapiens]
Length = 325
Score = 40.0 bits (92), Expect = 0.003
Identities = 40/162 (24%), Positives = 62/162 (38%), Gaps = 30/162 (18%)
Query: 145 CTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMF 204
C I G E+G+ L + + SG V + H +++ DI SR MF + D + ++F
Sbjct: 160 CIIAGHESGE-LNQYSAKSGEVLVNVKEHSRQINDIQLSR---DMTMFVTASKDNTAKLF 215
Query: 205 DLRHLEH-STIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPV---- 259
D LEH T E P + L PNY + G E +DV T +
Sbjct: 216 DSTTLEHQKTFRTERPVNSAAL-------SPNYDHVVLGGGQEA--MDVTTTSTRIGKFE 266
Query: 260 ------------ARLNNHRACVNGIAWAPHSSCHICTAADDH 289
R+ H +N +A+ P + D +
Sbjct: 267 ARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGY 308
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 40.0 bits (92), Expect = 0.003
Identities = 56/242 (23%), Positives = 89/242 (36%), Gaps = 57/242 (23%)
Query: 128 WNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHV---KTQLIAHDKEVYDIAFSR 184
WN V LL + S D+T IW L G LV H Q + +K+V + ++
Sbjct: 177 WNPVSD-LLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNS 235
Query: 185 AGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHH-PLLRLCWNKQDPNYLATMAMD 243
G + A+ DG R++ ST+ QH P+ L WNK+ N++ + +D
Sbjct: 236 EG---TLLATGSYDGFARIWTKDGNLASTL----GQHKGPIFALKWNKKG-NFILSAGVD 287
Query: 244 GMEVV------------------ILDVR-------VPCT--------------PVARLNN 264
++ LDV C+ P+
Sbjct: 288 KTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQG 347
Query: 265 HRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWAST 324
H VN I W P + + + +DD IW ++Q + D EI ++W+ T
Sbjct: 348 HTNEVNAIKWDPTGNL-LASCSDDMTLKIWSMKQ-DNCVHD---LQAHNKEIYTIKWSPT 402
Query: 325 QP 326
P
Sbjct: 403 GP 404
Score = 36.2 bits (82), Expect = 0.044
Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 20/115 (17%)
Query: 135 LLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRD---- 190
LL + S D T IW ++ + L AH+KE+Y I +S G G +
Sbjct: 363 LLASCSDDMTLKIWSMKQDNCVH-----------DLQAHNKEIYTIKWSPTGPGTNNPNA 411
Query: 191 --MFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMD 243
M AS D +VR++D ++ I+ +H + D YLA+ + D
Sbjct: 412 NLMLASASFDSTVRLWD---VDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFD 463
>gi|4885105 chromatin assembly factor 1 subunit B [Homo sapiens]
Length = 559
Score = 40.0 bits (92), Expect = 0.003
Identities = 47/201 (23%), Positives = 84/201 (41%), Gaps = 32/201 (15%)
Query: 136 LGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASV 195
L ++ +DT IW +E G G+ + + L H K V + FS G ++ AS
Sbjct: 32 LASAGVDTNVRIWKVEKGPD-GKAIV---EFLSNLARHTKAVNVVRFSPTG---EILASG 84
Query: 196 GADGSVRMFDLR-HLEHSTIIYEDPQHHPLLR------------------LCWNKQDPNY 236
G D + ++ + + E I ++D L + +CW D N
Sbjct: 85 GDDAVILLWKVNDNKEPEQIAFQDEDEAQLNKENWTVVKTLRGHLEDVYDICW-ATDGNL 143
Query: 237 LATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDI 296
+A+ ++D +I DV ++ N H++ V G+ W P ++ T + D ++ I
Sbjct: 144 MASASVDNT-AIIWDVSKG-QKISIFNEHKSYVQGVTWDPLGQ-YVATLSCDRVLRVYSI 200
Query: 297 QQMPRA--IEDPILAYTAEGE 315
Q+ A + + AEGE
Sbjct: 201 QKKRVAFNVSKMLSGIGAEGE 221
Score = 30.4 bits (67), Expect = 2.4
Identities = 35/155 (22%), Positives = 58/155 (37%), Gaps = 36/155 (23%)
Query: 86 DLLATSGD--YLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEV------------ 131
++LA+ GD + +W+V + + + + A L +W V
Sbjct: 79 EILASGGDDAVILLWKVNDNKEPEQIAFQDEDE----AQLNKENWTVVKTLRGHLEDVYD 134
Query: 132 -----DPYLLGTSSIDTTCTIWGLETGQVLGRVN----LVSG--------HVKTQLIAHD 174
D L+ ++S+D T IW + GQ + N V G +V T
Sbjct: 135 ICWATDGNLMASASVDNTAIIWDVSKGQKISIFNEHKSYVQGVTWDPLGQYVATLSCDRV 194
Query: 175 KEVYDIAFSR-AGGGRDMFASVGADGSVRMFDLRH 208
VY I R A M + +GA+G R + + H
Sbjct: 195 LRVYSIQKKRVAFNVSKMLSGIGAEGEARSYRMFH 229
>gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens]
Length = 1298
Score = 39.7 bits (91), Expect = 0.004
Identities = 41/153 (26%), Positives = 66/153 (43%), Gaps = 18/153 (11%)
Query: 8 KEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKVQLVGLDEESSEFICRNTFDH 67
K ++KY+ P V+ +WS + + +A G E+ N +V V SS+ + H
Sbjct: 489 KVLHKYKHPAAVFGCDWS--QNNKDMIATGC--EDTNVRVYYVAT---SSDQPLKVFSGH 541
Query: 68 PYPTTKLMWIPDTKGVYPDLLATSGD-YLRVWRVGETETRLECLLNNNKNSDFCAPLTSF 126
+ W P +G+ L + S D +R+W T+ C+ N + AP+
Sbjct: 542 TAKVFHVKWSPLREGI---LCSGSDDGTVRIWDY----TQDACI---NILNGHTAPVRGL 591
Query: 127 DWNEVDPYLLGTSSIDTTCTIWGLETGQVLGRV 159
WN PYLL + S D T +W G + V
Sbjct: 592 MWNTEIPYLLISGSWDYTIKVWDTREGTCVDTV 624
Score = 39.3 bits (90), Expect = 0.005
Identities = 50/244 (20%), Positives = 100/244 (40%), Gaps = 46/244 (18%)
Query: 82 GVYPDLLATSGDYLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSI 141
G+Y D+ A D+LR +G ET +C + DP LL T+S
Sbjct: 351 GLY-DMGAKKWDFLR--DLGHVETIFDCKFKPD-----------------DPNLLATASF 390
Query: 142 DTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSV 201
D T +W + T L V G ++ +Y ++++ GG + +G+
Sbjct: 391 DGTIKVWDINT---LTAVYTSPG--------NEGVIYSLSWA-PGGLNCIAGGTSRNGAF 438
Query: 202 RMFDLRHLEHSTIIYEDPQH--HPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPV 259
+ +++ II +H + + + W+ +D +AT + DG + +R V
Sbjct: 439 ----IWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCI----IRTIDGKV 490
Query: 260 ARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAE-GEINN 318
H A V G W+ ++ I T +D ++ + + + P+ ++ ++ +
Sbjct: 491 LHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVY---YVATSSDQPLKVFSGHTAKVFH 547
Query: 319 VQWA 322
V+W+
Sbjct: 548 VKWS 551
Score = 37.4 bits (85), Expect = 0.020
Identities = 42/190 (22%), Positives = 82/190 (43%), Gaps = 15/190 (7%)
Query: 127 DWNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAG 186
DW++ + ++ T DT ++ + T + + SGH +V+ + +S
Sbjct: 504 DWSQNNKDMIATGCEDTNVRVYYVATSSDQP-LKVFSGHTA--------KVFHVKWSPLR 554
Query: 187 GGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGME 246
G + S DG+VR++D + + + I + P+ L WN + P L + + D
Sbjct: 555 EG--ILCSGSDDGTVRIWD--YTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWD-YT 609
Query: 247 VVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDP 306
+ + D R T V + +H A V G+ P + + + D +W + + ++
Sbjct: 610 IKVWDTREG-TCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLTALVTPVQIN 668
Query: 307 ILAYTAEGEI 316
ILA + EI
Sbjct: 669 ILADRSWEEI 678
Score = 32.3 bits (72), Expect = 0.63
Identities = 41/209 (19%), Positives = 80/209 (38%), Gaps = 23/209 (11%)
Query: 90 TSGDYLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSIDTTCTIWG 149
TS + +W V + + ++ + N FC W+ D + T S D C I
Sbjct: 432 TSRNGAFIWNVQKGKI-IQRFNEHGTNGIFCIA-----WSHKDSKRIATCSSDGFCIIRT 485
Query: 150 LETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHL 209
++ G+VL + H V+ +S+ +DM A+ D +VR++ +
Sbjct: 486 ID-GKVLHKYK------------HPAAVFGCDWSQ--NNKDMIATGCEDTNVRVYYVATS 530
Query: 210 EHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACV 269
+ + + W+ L + + DG + + C + LN H A V
Sbjct: 531 SDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINI--LNGHTAPV 588
Query: 270 NGIAWAPHSSCHICTAADDHQALIWDIQQ 298
G+ W + + + D+ +WD ++
Sbjct: 589 RGLMWNTEIPYLLISGSWDYTIKVWDTRE 617
Score = 30.8 bits (68), Expect = 1.8
Identities = 9/39 (23%), Positives = 22/39 (56%)
Query: 260 ARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQ 298
A ++ H+ + I+W PH+ + + D+ +IW++ +
Sbjct: 53 AIMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAE 91
>gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens]
Length = 1322
Score = 39.7 bits (91), Expect = 0.004
Identities = 41/153 (26%), Positives = 66/153 (43%), Gaps = 18/153 (11%)
Query: 8 KEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKVQLVGLDEESSEFICRNTFDH 67
K ++KY+ P V+ +WS + + +A G E+ N +V V SS+ + H
Sbjct: 513 KVLHKYKHPAAVFGCDWS--QNNKDMIATGC--EDTNVRVYYVAT---SSDQPLKVFSGH 565
Query: 68 PYPTTKLMWIPDTKGVYPDLLATSGD-YLRVWRVGETETRLECLLNNNKNSDFCAPLTSF 126
+ W P +G+ L + S D +R+W T+ C+ N + AP+
Sbjct: 566 TAKVFHVKWSPLREGI---LCSGSDDGTVRIWDY----TQDACI---NILNGHTAPVRGL 615
Query: 127 DWNEVDPYLLGTSSIDTTCTIWGLETGQVLGRV 159
WN PYLL + S D T +W G + V
Sbjct: 616 MWNTEIPYLLISGSWDYTIKVWDTREGTCVDTV 648
Score = 39.3 bits (90), Expect = 0.005
Identities = 50/244 (20%), Positives = 100/244 (40%), Gaps = 46/244 (18%)
Query: 82 GVYPDLLATSGDYLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSI 141
G+Y D+ A D+LR +G ET +C + DP LL T+S
Sbjct: 375 GLY-DMGAKKWDFLR--DLGHVETIFDCKFKPD-----------------DPNLLATASF 414
Query: 142 DTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSV 201
D T +W + T L V G ++ +Y ++++ GG + +G+
Sbjct: 415 DGTIKVWDINT---LTAVYTSPG--------NEGVIYSLSWA-PGGLNCIAGGTSRNGAF 462
Query: 202 RMFDLRHLEHSTIIYEDPQH--HPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPV 259
+ +++ II +H + + + W+ +D +AT + DG + +R V
Sbjct: 463 ----IWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCI----IRTIDGKV 514
Query: 260 ARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAE-GEINN 318
H A V G W+ ++ I T +D ++ + + + P+ ++ ++ +
Sbjct: 515 LHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVY---YVATSSDQPLKVFSGHTAKVFH 571
Query: 319 VQWA 322
V+W+
Sbjct: 572 VKWS 575
Score = 37.4 bits (85), Expect = 0.020
Identities = 42/190 (22%), Positives = 82/190 (43%), Gaps = 15/190 (7%)
Query: 127 DWNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAG 186
DW++ + ++ T DT ++ + T + + SGH +V+ + +S
Sbjct: 528 DWSQNNKDMIATGCEDTNVRVYYVATSSDQP-LKVFSGHTA--------KVFHVKWSPLR 578
Query: 187 GGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGME 246
G + S DG+VR++D + + + I + P+ L WN + P L + + D
Sbjct: 579 EG--ILCSGSDDGTVRIWD--YTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWD-YT 633
Query: 247 VVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDP 306
+ + D R T V + +H A V G+ P + + + D +W + + ++
Sbjct: 634 IKVWDTREG-TCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLTALVTPVQIN 692
Query: 307 ILAYTAEGEI 316
ILA + EI
Sbjct: 693 ILADRSWEEI 702
Score = 32.3 bits (72), Expect = 0.63
Identities = 41/209 (19%), Positives = 80/209 (38%), Gaps = 23/209 (11%)
Query: 90 TSGDYLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSIDTTCTIWG 149
TS + +W V + + ++ + N FC W+ D + T S D C I
Sbjct: 456 TSRNGAFIWNVQKGKI-IQRFNEHGTNGIFCIA-----WSHKDSKRIATCSSDGFCIIRT 509
Query: 150 LETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHL 209
++ G+VL + H V+ +S+ +DM A+ D +VR++ +
Sbjct: 510 ID-GKVLHKYK------------HPAAVFGCDWSQ--NNKDMIATGCEDTNVRVYYVATS 554
Query: 210 EHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACV 269
+ + + W+ L + + DG + + C + LN H A V
Sbjct: 555 SDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINI--LNGHTAPV 612
Query: 270 NGIAWAPHSSCHICTAADDHQALIWDIQQ 298
G+ W + + + D+ +WD ++
Sbjct: 613 RGLMWNTEIPYLLISGSWDYTIKVWDTRE 641
Score = 30.8 bits (68), Expect = 1.8
Identities = 9/39 (23%), Positives = 22/39 (56%)
Query: 260 ARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQ 298
A ++ H+ + I+W PH+ + + D+ +IW++ +
Sbjct: 77 AIMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAE 115
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 39.7 bits (91), Expect = 0.004
Identities = 58/242 (23%), Positives = 89/242 (36%), Gaps = 57/242 (23%)
Query: 128 WNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQ---LIAHDKEVYDIAFSR 184
WN V LL + S D+T IW L G LV H + + +K+V + ++
Sbjct: 189 WNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNT 247
Query: 185 AGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHH-PLLRLCWNKQDPNYLATMAMD 243
G + A+ DG R++ E + QH P+ L WN++ NY+ + +D
Sbjct: 248 NG---TLLATGSYDGFARIW----TEDGNLASTLGQHKGPIFALKWNRKG-NYILSAGVD 299
Query: 244 GMEVV------------------ILDV--------------------RVPC-TPVARLNN 264
++ LDV R+ C PV
Sbjct: 300 KTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQG 359
Query: 265 HRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWAST 324
H VN I W P S + + +DD IW ++Q I D EI ++W+ T
Sbjct: 360 HTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQ-EVCIHD---LQAHNKEIYTIKWSPT 414
Query: 325 QP 326
P
Sbjct: 415 GP 416
Score = 39.7 bits (91), Expect = 0.004
Identities = 51/230 (22%), Positives = 90/230 (39%), Gaps = 49/230 (21%)
Query: 42 EYNNKVQLVGLDEESSEFICRNTFDHPYPTTK--------LMWIPDTKGVYPDLLATSGD 93
++ N + +CR D P T + + W P LLA+ D
Sbjct: 327 DWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGM-----LLASCSD 381
Query: 94 --YLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDP--------YLLGTSSIDT 143
L++W + + E + L +NK + + W+ P +L ++S D+
Sbjct: 382 DMTLKIWSMKQ-EVCIHDLQAHNKE------IYTIKWSPTGPATSNPNSNIMLASASFDS 434
Query: 144 TCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRM 203
T +W +E G V H T+ H + VY +AFS G AS D V +
Sbjct: 435 TVRLWDIERG--------VCTHTLTK---HQEPVYSVAFSPDG---KYLASGSFDKCVHI 480
Query: 204 FDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVR 253
+ + + +++ + +CWN + + + A DG V +LD+R
Sbjct: 481 W---NTQSGNLVHSYRGTGGIFEVCWNARG-DKVGASASDG-SVCVLDLR 525
Score = 36.6 bits (83), Expect = 0.033
Identities = 62/242 (25%), Positives = 89/242 (36%), Gaps = 54/242 (22%)
Query: 72 TKLMWIPDTKGVYPDLLATSGDYLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEV 131
T L W +T G LLAT G Y R+ + L L +K P+ + WN
Sbjct: 241 TSLDW--NTNGT---LLAT-GSYDGFARIWTEDGNLASTLGQHKG-----PIFALKWNRK 289
Query: 132 DPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSR----AGG 187
Y+L ++ +D T IW TG+ K Q H D+ + A
Sbjct: 290 GNYIL-SAGVDKTTIIWDAHTGEA-----------KQQFPFHSAPALDVDWQNNTTFASC 337
Query: 188 GRDMFASV---GADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDG 244
DM V G D V+ F H I DP LL C D L +M
Sbjct: 338 STDMCIHVCRLGCDRPVKTFQ-GHTNEVNAIKWDPSGM-LLASC---SDDMTLKIWSMK- 391
Query: 245 MEVVILDVRVPCTPVARLNNHRACVNGIAWAP--------HSSCHICTAADDHQALIWDI 296
EV I D++ H + I W+P +S+ + +A+ D +WDI
Sbjct: 392 QEVCIHDLQA----------HNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI 441
Query: 297 QQ 298
++
Sbjct: 442 ER 443
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 39.7 bits (91), Expect = 0.004
Identities = 58/242 (23%), Positives = 89/242 (36%), Gaps = 57/242 (23%)
Query: 128 WNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQ---LIAHDKEVYDIAFSR 184
WN V LL + S D+T IW L G LV H + + +K+V + ++
Sbjct: 189 WNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNT 247
Query: 185 AGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHH-PLLRLCWNKQDPNYLATMAMD 243
G + A+ DG R++ E + QH P+ L WN++ NY+ + +D
Sbjct: 248 NG---TLLATGSYDGFARIW----TEDGNLASTLGQHKGPIFALKWNRKG-NYILSAGVD 299
Query: 244 GMEVV------------------ILDV--------------------RVPC-TPVARLNN 264
++ LDV R+ C PV
Sbjct: 300 KTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQG 359
Query: 265 HRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWAST 324
H VN I W P S + + +DD IW ++Q I D EI ++W+ T
Sbjct: 360 HTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQ-EVCIHD---LQAHNKEIYTIKWSPT 414
Query: 325 QP 326
P
Sbjct: 415 GP 416
Score = 39.7 bits (91), Expect = 0.004
Identities = 51/230 (22%), Positives = 90/230 (39%), Gaps = 49/230 (21%)
Query: 42 EYNNKVQLVGLDEESSEFICRNTFDHPYPTTK--------LMWIPDTKGVYPDLLATSGD 93
++ N + +CR D P T + + W P LLA+ D
Sbjct: 327 DWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGM-----LLASCSD 381
Query: 94 --YLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDP--------YLLGTSSIDT 143
L++W + + E + L +NK + + W+ P +L ++S D+
Sbjct: 382 DMTLKIWSMKQ-EVCIHDLQAHNKE------IYTIKWSPTGPATSNPNSNIMLASASFDS 434
Query: 144 TCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRM 203
T +W +E G V H T+ H + VY +AFS G AS D V +
Sbjct: 435 TVRLWDIERG--------VCTHTLTK---HQEPVYSVAFSPDG---KYLASGSFDKCVHI 480
Query: 204 FDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVR 253
+ + + +++ + +CWN + + + A DG V +LD+R
Sbjct: 481 W---NTQSGNLVHSYRGTGGIFEVCWNARG-DKVGASASDG-SVCVLDLR 525
Score = 36.6 bits (83), Expect = 0.033
Identities = 62/242 (25%), Positives = 89/242 (36%), Gaps = 54/242 (22%)
Query: 72 TKLMWIPDTKGVYPDLLATSGDYLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEV 131
T L W +T G LLAT G Y R+ + L L +K P+ + WN
Sbjct: 241 TSLDW--NTNGT---LLAT-GSYDGFARIWTEDGNLASTLGQHKG-----PIFALKWNRK 289
Query: 132 DPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSR----AGG 187
Y+L ++ +D T IW TG+ K Q H D+ + A
Sbjct: 290 GNYIL-SAGVDKTTIIWDAHTGEA-----------KQQFPFHSAPALDVDWQNNTTFASC 337
Query: 188 GRDMFASV---GADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDG 244
DM V G D V+ F H I DP LL C D L +M
Sbjct: 338 STDMCIHVCRLGCDRPVKTFQ-GHTNEVNAIKWDPSGM-LLASC---SDDMTLKIWSMK- 391
Query: 245 MEVVILDVRVPCTPVARLNNHRACVNGIAWAP--------HSSCHICTAADDHQALIWDI 296
EV I D++ H + I W+P +S+ + +A+ D +WDI
Sbjct: 392 QEVCIHDLQA----------HNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI 441
Query: 297 QQ 298
++
Sbjct: 442 ER 443
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 39.7 bits (91), Expect = 0.004
Identities = 58/242 (23%), Positives = 89/242 (36%), Gaps = 57/242 (23%)
Query: 128 WNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQ---LIAHDKEVYDIAFSR 184
WN V LL + S D+T IW L G LV H + + +K+V + ++
Sbjct: 240 WNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNT 298
Query: 185 AGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHH-PLLRLCWNKQDPNYLATMAMD 243
G + A+ DG R++ E + QH P+ L WN++ NY+ + +D
Sbjct: 299 NG---TLLATGSYDGFARIW----TEDGNLASTLGQHKGPIFALKWNRKG-NYILSAGVD 350
Query: 244 GMEVV------------------ILDV--------------------RVPC-TPVARLNN 264
++ LDV R+ C PV
Sbjct: 351 KTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQG 410
Query: 265 HRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWAST 324
H VN I W P S + + +DD IW ++Q I D EI ++W+ T
Sbjct: 411 HTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQ-EVCIHD---LQAHNKEIYTIKWSPT 465
Query: 325 QP 326
P
Sbjct: 466 GP 467
Score = 39.7 bits (91), Expect = 0.004
Identities = 51/230 (22%), Positives = 90/230 (39%), Gaps = 49/230 (21%)
Query: 42 EYNNKVQLVGLDEESSEFICRNTFDHPYPTTK--------LMWIPDTKGVYPDLLATSGD 93
++ N + +CR D P T + + W P LLA+ D
Sbjct: 378 DWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGM-----LLASCSD 432
Query: 94 --YLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDP--------YLLGTSSIDT 143
L++W + + E + L +NK + + W+ P +L ++S D+
Sbjct: 433 DMTLKIWSMKQ-EVCIHDLQAHNKE------IYTIKWSPTGPATSNPNSNIMLASASFDS 485
Query: 144 TCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRM 203
T +W +E G V H T+ H + VY +AFS G AS D V +
Sbjct: 486 TVRLWDIERG--------VCTHTLTK---HQEPVYSVAFSPDG---KYLASGSFDKCVHI 531
Query: 204 FDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVR 253
+ + + +++ + +CWN + + + A DG V +LD+R
Sbjct: 532 W---NTQSGNLVHSYRGTGGIFEVCWNARG-DKVGASASDG-SVCVLDLR 576
Score = 36.6 bits (83), Expect = 0.033
Identities = 62/242 (25%), Positives = 89/242 (36%), Gaps = 54/242 (22%)
Query: 72 TKLMWIPDTKGVYPDLLATSGDYLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEV 131
T L W +T G LLAT G Y R+ + L L +K P+ + WN
Sbjct: 292 TSLDW--NTNGT---LLAT-GSYDGFARIWTEDGNLASTLGQHKG-----PIFALKWNRK 340
Query: 132 DPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSR----AGG 187
Y+L ++ +D T IW TG+ K Q H D+ + A
Sbjct: 341 GNYIL-SAGVDKTTIIWDAHTGEA-----------KQQFPFHSAPALDVDWQNNTTFASC 388
Query: 188 GRDMFASV---GADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDG 244
DM V G D V+ F H I DP LL C D L +M
Sbjct: 389 STDMCIHVCRLGCDRPVKTFQ-GHTNEVNAIKWDPSGM-LLASC---SDDMTLKIWSMK- 442
Query: 245 MEVVILDVRVPCTPVARLNNHRACVNGIAWAP--------HSSCHICTAADDHQALIWDI 296
EV I D++ H + I W+P +S+ + +A+ D +WDI
Sbjct: 443 QEVCIHDLQA----------HNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI 492
Query: 297 QQ 298
++
Sbjct: 493 ER 494
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 39.7 bits (91), Expect = 0.004
Identities = 58/242 (23%), Positives = 89/242 (36%), Gaps = 57/242 (23%)
Query: 128 WNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQ---LIAHDKEVYDIAFSR 184
WN V LL + S D+T IW L G LV H + + +K+V + ++
Sbjct: 240 WNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNT 298
Query: 185 AGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHH-PLLRLCWNKQDPNYLATMAMD 243
G + A+ DG R++ E + QH P+ L WN++ NY+ + +D
Sbjct: 299 NG---TLLATGSYDGFARIW----TEDGNLASTLGQHKGPIFALKWNRKG-NYILSAGVD 350
Query: 244 GMEVV------------------ILDV--------------------RVPC-TPVARLNN 264
++ LDV R+ C PV
Sbjct: 351 KTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQG 410
Query: 265 HRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWAST 324
H VN I W P S + + +DD IW ++Q I D EI ++W+ T
Sbjct: 411 HTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQ-EVCIHD---LQAHNKEIYTIKWSPT 465
Query: 325 QP 326
P
Sbjct: 466 GP 467
Score = 39.7 bits (91), Expect = 0.004
Identities = 51/230 (22%), Positives = 90/230 (39%), Gaps = 49/230 (21%)
Query: 42 EYNNKVQLVGLDEESSEFICRNTFDHPYPTTK--------LMWIPDTKGVYPDLLATSGD 93
++ N + +CR D P T + + W P LLA+ D
Sbjct: 378 DWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGM-----LLASCSD 432
Query: 94 --YLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDP--------YLLGTSSIDT 143
L++W + + E + L +NK + + W+ P +L ++S D+
Sbjct: 433 DMTLKIWSMKQ-EVCIHDLQAHNKE------IYTIKWSPTGPATSNPNSNIMLASASFDS 485
Query: 144 TCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRM 203
T +W +E G V H T+ H + VY +AFS G AS D V +
Sbjct: 486 TVRLWDIERG--------VCTHTLTK---HQEPVYSVAFSPDG---KYLASGSFDKCVHI 531
Query: 204 FDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVR 253
+ + + +++ + +CWN + + + A DG V +LD+R
Sbjct: 532 W---NTQSGNLVHSYRGTGGIFEVCWNARG-DKVGASASDG-SVCVLDLR 576
Score = 36.6 bits (83), Expect = 0.033
Identities = 62/242 (25%), Positives = 89/242 (36%), Gaps = 54/242 (22%)
Query: 72 TKLMWIPDTKGVYPDLLATSGDYLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEV 131
T L W +T G LLAT G Y R+ + L L +K P+ + WN
Sbjct: 292 TSLDW--NTNGT---LLAT-GSYDGFARIWTEDGNLASTLGQHKG-----PIFALKWNRK 340
Query: 132 DPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSR----AGG 187
Y+L ++ +D T IW TG+ K Q H D+ + A
Sbjct: 341 GNYIL-SAGVDKTTIIWDAHTGEA-----------KQQFPFHSAPALDVDWQNNTTFASC 388
Query: 188 GRDMFASV---GADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDG 244
DM V G D V+ F H I DP LL C D L +M
Sbjct: 389 STDMCIHVCRLGCDRPVKTFQ-GHTNEVNAIKWDPSGM-LLASC---SDDMTLKIWSMK- 442
Query: 245 MEVVILDVRVPCTPVARLNNHRACVNGIAWAP--------HSSCHICTAADDHQALIWDI 296
EV I D++ H + I W+P +S+ + +A+ D +WDI
Sbjct: 443 QEVCIHDLQA----------HNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI 492
Query: 297 QQ 298
++
Sbjct: 493 ER 494
>gi|55741849 WD repeat domain 22 [Homo sapiens]
Length = 942
Score = 39.3 bits (90), Expect = 0.005
Identities = 39/166 (23%), Positives = 68/166 (40%), Gaps = 9/166 (5%)
Query: 167 KTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTI--IYEDPQHHPL 224
K L+ H V I FS GG S G D V ++ + HS + I +HH
Sbjct: 46 KKDLLGHFGCVNAIEFSNNGG--QWLVSGGDDRRVLLWHMEQAIHSRVKPIQLKGEHHSN 103
Query: 225 LRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICT 284
+ C N + +V++ DV + + H V G++ +P + +
Sbjct: 104 I-FCLAFNSGNTKVFSGGNDEQVILHDVE--SSETLDVFAHEDAVYGLSVSPVNDNIFAS 160
Query: 285 AADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWASTQPDWIA 330
++DD + LIWDI++ P +P ++V + +P +A
Sbjct: 161 SSDDGRVLIWDIRESPHG--EPFCLANYPSAFHSVMFNPVEPRLLA 204
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 39.3 bits (90), Expect = 0.005
Identities = 48/207 (23%), Positives = 80/207 (38%), Gaps = 30/207 (14%)
Query: 132 DPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDM 191
D +L T S D W +GQ+L R+ +G VK F R +
Sbjct: 32 DGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVK--------------FCRFSPDGHL 77
Query: 192 FASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILD 251
FAS D +VR++D+ + ++ H + D LA+ D V++ D
Sbjct: 78 FASASCDCTVRLWDVARAKCLRVL---KGHQRSVETVSFSPDSRQLASGGWD-KRVMLWD 133
Query: 252 VRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIED------ 305
V+ + L HR + ++P +C + T + D IWD++ + A+
Sbjct: 134 VQ-SGQMLRLLVGHRDSIQSSDFSPTVNC-LATGSWDSTVHIWDLRMVTPAVSHQALEGH 191
Query: 306 ----PILAYTAEGEINNVQWASTQPDW 328
L Y+A G + + W T W
Sbjct: 192 SANISCLCYSASGLLASGSWDKTIHIW 218
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.444
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,862,833
Number of Sequences: 37866
Number of extensions: 592376
Number of successful extensions: 1509
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 88
Number of HSP's that attempted gapping in prelim test: 1269
Number of HSP's gapped (non-prelim): 297
length of query: 342
length of database: 18,247,518
effective HSP length: 103
effective length of query: 239
effective length of database: 14,347,320
effective search space: 3429009480
effective search space used: 3429009480
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.