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Search of human proteins with 108773808
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|108773808 hypothetical protein LOC51244 [Homo sapiens]
(467 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|108773808 hypothetical protein LOC51244 [Homo sapiens] 948 0.0
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 57 5e-08
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 54 2e-07
gi|92859701 myosin VI [Homo sapiens] 53 7e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 52 9e-07
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 52 1e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 51 2e-06
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 51 2e-06
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 50 3e-06
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 50 3e-06
gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 50 4e-06
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 50 4e-06
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 50 4e-06
gi|148746195 trichohyalin [Homo sapiens] 50 6e-06
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 50 6e-06
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 49 7e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 49 1e-05
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 47 3e-05
gi|87299628 biorientation of chromosomes in cell division 1-like... 47 5e-05
gi|219803769 trichoplein [Homo sapiens] 46 6e-05
gi|14150056 trichoplein [Homo sapiens] 46 6e-05
gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar)... 45 1e-04
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa... 45 1e-04
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap... 45 1e-04
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 45 1e-04
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 45 1e-04
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] 45 2e-04
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 44 2e-04
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 44 2e-04
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 44 2e-04
>gi|108773808 hypothetical protein LOC51244 [Homo sapiens]
Length = 467
Score = 948 bits (2450), Expect = 0.0
Identities = 467/467 (100%), Positives = 467/467 (100%)
Query: 1 MDRRKKPLDVTASSLVDLKAELFRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVG 60
MDRRKKPLDVTASSLVDLKAELFRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVG
Sbjct: 1 MDRRKKPLDVTASSLVDLKAELFRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVG 60
Query: 61 VSNRAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIID 120
VSNRAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIID
Sbjct: 61 VSNRAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIID 120
Query: 121 KRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDL 180
KRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDL
Sbjct: 121 KRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDL 180
Query: 181 PDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRE 240
PDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRE
Sbjct: 181 PDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRE 240
Query: 241 NEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLR 300
NEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLR
Sbjct: 241 NEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLR 300
Query: 301 QKKMKKSKEGGTEEENRDGDVIGPLPPEPEAVPTPRPAAQSSKVEVIVQERKDTKPGVPH 360
QKKMKKSKEGGTEEENRDGDVIGPLPPEPEAVPTPRPAAQSSKVEVIVQERKDTKPGVPH
Sbjct: 301 QKKMKKSKEGGTEEENRDGDVIGPLPPEPEAVPTPRPAAQSSKVEVIVQERKDTKPGVPH 360
Query: 361 IREWDRGKEFSFGYWSKRQSDLRAERDPEFAPPSDYFVGQKRTGFSSSQAWSRPGPAQSD 420
IREWDRGKEFSFGYWSKRQSDLRAERDPEFAPPSDYFVGQKRTGFSSSQAWSRPGPAQSD
Sbjct: 361 IREWDRGKEFSFGYWSKRQSDLRAERDPEFAPPSDYFVGQKRTGFSSSQAWSRPGPAQSD 420
Query: 421 PGQCPDQSHGPSPEHTSPTPAPDNPPQAPTVTFKTLDDMISYYKQVT 467
PGQCPDQSHGPSPEHTSPTPAPDNPPQAPTVTFKTLDDMISYYKQVT
Sbjct: 421 PGQCPDQSHGPSPEHTSPTPAPDNPPQAPTVTFKTLDDMISYYKQVT 467
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 56.6 bits (135), Expect = 5e-08
Identities = 67/328 (20%), Positives = 138/328 (42%), Gaps = 41/328 (12%)
Query: 19 KAELFRKQEEF---KQEKLLKDSGVFGKP--KTTNKKPSIWSKQNVGVSNRAEKDAEQKI 73
K E R+QEE K+EK+ + + + K ++ +W K+ + ++KI
Sbjct: 347 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI 406
Query: 74 EEQKTLDKAREKLEEKAKLYEKMTK-----------GDFIDEEVEDMY----LVDFTQKI 118
EQ+ + EK+ E+ K E+ K + I E+ + M+ + +KI
Sbjct: 407 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKI 466
Query: 119 IDKRKEMEASGAHRDSQKAGERDD---DEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRC 175
++ K E R +K E+++ +E + E E + + W + +
Sbjct: 467 REEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVW-RQEEKIREQEEK 525
Query: 176 MRKDLPDLLEMDKNLQGRLFISPANEK-----TLLSEDMRKELQRQQWEEEEREALKRPM 230
+R+ + ++ ++ + + EK + E+ R+E + + W +EE+ +
Sbjct: 526 IREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEK 585
Query: 231 GPVHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKA 290
E IRE E ++ +E K K E +REQ + + E I+E+ +
Sbjct: 586 VWRQEEKIREQEEKR-----------QEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634
Query: 291 ILE-ARLAKLRQKKMKKSKEGGTEEENR 317
I E + + +++KM + +E E+E +
Sbjct: 635 IREQEEMTQEQEEKMGEQEEKMCEQEEK 662
Score = 48.1 bits (113), Expect = 2e-05
Identities = 66/348 (18%), Positives = 154/348 (44%), Gaps = 44/348 (12%)
Query: 19 KAELFRKQEEFK-QEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAE-----QK 72
+A+++R++E+ + QE+ +++ + K ++ I ++ + + ++ E +K
Sbjct: 429 EAKMWRQEEKIREQEEKIREQ----EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 484
Query: 73 IEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAHR 132
I EQ+ + + +EK+ E+ + K + + EE + + +KI ++ ++M R
Sbjct: 485 IHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEK----IREQEEKIREQEEKM-----WR 535
Query: 133 DSQKAGERDD---DEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKN 189
+K E+++ +EE + E E ++ +E D + R +R+ + +
Sbjct: 536 QEEKIREQEEMWREEEKMHEQEKIWEEEKRQE---QEDKMWRQEEKIREQEEKVWRQE-- 590
Query: 190 LQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRENEARQLGVG 249
EK E+ R+E + + W++EE+ + E IRE E +
Sbjct: 591 -----------EKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQE 639
Query: 250 YFAFARDKELRNKQMKTLEM---LREQTTDQRTKRENIKEKRKAILEARLAKLRQKK--M 304
+++++ ++ K E ++EQ + E I+E+ K I E K+R+++ M
Sbjct: 640 EMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQE-EKIREQEEMM 698
Query: 305 KKSKEGGTEEENRDGDVIGPLPPEPEAVPTPRPAAQSSKVEVIVQERK 352
++ +E E+E + + + + E + +V + QE K
Sbjct: 699 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 746
Score = 41.2 bits (95), Expect = 0.002
Identities = 53/266 (19%), Positives = 110/266 (41%), Gaps = 18/266 (6%)
Query: 56 KQNVGVSNRAEKDAEQKIEEQKTLDKAREKLEEKAKLY----EKMTKGDFIDEEVEDMYL 111
++N + + + +K E Q + + + KLE +AKL + + D + +E++ +
Sbjct: 221 EKNAKLQEKLQLVESEKSEIQLNVKELKRKLE-RAKLLLPQQQLQAEADHLGKELQSV-- 277
Query: 112 VDFTQKIIDKRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGR 171
+ K+ + +E E + Q+ + EE + E E Q+ E+ + + +
Sbjct: 278 ---SAKLQAQVEENELWN-RLNQQQEEKMWRQEEKIQEWE-EKIQEQEEKIREQEEKIRE 332
Query: 172 SRRCMRKDLPDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMG 231
MR+ + E ++ ++ + E E+ + + WE+EE+ + M
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQ------EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 386
Query: 232 PVHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAI 291
E IRE E + +K ++++ E +EQ + E I+E+ + I
Sbjct: 387 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 446
Query: 292 LEARLAKLRQKKMKKSKEGGTEEENR 317
E RQ++ +E EEE R
Sbjct: 447 REQEKKMWRQEEKIHEQEKIREEEKR 472
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 54.3 bits (129), Expect = 2e-07
Identities = 66/382 (17%), Positives = 173/382 (45%), Gaps = 39/382 (10%)
Query: 21 ELFRKQEE-FKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQKTL 79
+++R++E ++QEK +++ + K +++ +W + + ++ E+++ EQ+ +
Sbjct: 370 KMWRQEERLWEQEKQMREQ----EQKMRDQEERMWEQ------DERLREKEERMREQEKM 419
Query: 80 DKAREKLEEKAKLYEKMTKGDFIDEEV-EDMYLVDFTQKIIDKRKEMEASGAHRDSQKAG 138
+ EK+ E+ K+ E+ K +E++ E+ + + +K+ ++ + M Q+
Sbjct: 420 WEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 479
Query: 139 ERDDDEENLPEGEIPPPQD---PSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQGRLF 195
+ +E+ + +P ++ E+ + + + +R D ++ +K + +
Sbjct: 480 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR-DQEEMWGQEKKMWRQEK 538
Query: 196 ISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPV----HYEDIRENEARQLGVGYF 251
+ ++ E+ ++ +++ W++EER K E +RE E +
Sbjct: 539 MREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMR------ 592
Query: 252 AFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILE-ARLAKLRQKKMKKSKEG 310
R+K++R ++ EM+REQ + + E ++E+ + + E + +++KM + +E
Sbjct: 593 --EREKKMREEE----EMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEK 646
Query: 311 GTEEENRDGDVIGPLPPEPEAVPTPRPAAQSSKVE-----VIVQERKDTKPGVPHIREWD 365
E+E + + LP + E + + K++ + QE+ + K + WD
Sbjct: 647 MWEQEEKMWEQ-QRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWD 705
Query: 366 RGKEFSFGYWSKRQSDLRAERD 387
+ K +R+ +R E +
Sbjct: 706 QEKMREEESMREREKKMREEEE 727
Score = 50.1 bits (118), Expect = 4e-06
Identities = 58/306 (18%), Positives = 138/306 (45%), Gaps = 20/306 (6%)
Query: 25 KQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEK--DAEQKIEEQKTLDKA 82
K+ ++EK+ ++ + + K ++ +Q + + E + E+K +Q+ L +
Sbjct: 437 KKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 496
Query: 83 REKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAHRDSQKAGERDD 142
+EKL E+ K+ E+ K +E++ D + +K + ++++M Q+ RD
Sbjct: 497 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 556
Query: 143 DEENLPEGE--IPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQGRLFISPAN 200
+++ + E Q+ ++ D + + R MR+ + E ++ ++ +
Sbjct: 557 EQKMWDQEERMEKKTQEQEKKTWDQEEKMREEER-MREREKKMREEEEMMREQ------E 609
Query: 201 EKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRENEARQLGVGYFAFARDKELR 260
EK E+ +E + + WE+EE+ + E + E E + ++K
Sbjct: 610 EKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE 669
Query: 261 NKQMKTLEMLREQ-----TTDQRTKRENIKEKR----KAILEARLAKLRQKKMKKSKEGG 311
+++M+ E ++EQ ++ K+ +EK+ + + E + R+KKM++ +E
Sbjct: 670 HEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMM 729
Query: 312 TEEENR 317
E+E +
Sbjct: 730 REQEEK 735
Score = 45.4 bits (106), Expect = 1e-04
Identities = 58/278 (20%), Positives = 114/278 (41%), Gaps = 46/278 (16%)
Query: 56 KQNVGVSNRAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFT 115
K+N + + +K E Q + + + KLE +AK + + + EE+
Sbjct: 225 KKNAELQEKLPLAESEKSEIQLNVKELKRKLE-RAKFLLPQVQTNTLQEEMW-------- 275
Query: 116 QKIIDKRKEMEASGAHRDSQKAGERD-DDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRR 174
R+E E + +K E+ EE L E E + + W R +
Sbjct: 276 ------RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMW--------RQEK 321
Query: 175 CMRKDLPDLLEMDKNLQGRLFI-------SPANEKTLLSEDMRKELQRQQWEEEEREALK 227
+R+ +L E +K L+ + + EK E+ +E + + W +EER +
Sbjct: 322 RLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 381
Query: 228 RPMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQ--MKTLEMLREQTTDQRTKRENIK 285
+ +R+ E R + +D+ LR K+ M+ E + EQ R +++ +
Sbjct: 382 EKQMREQEQKMRDQEERM-------WEQDERLREKEERMREQEKMWEQVEKMREEKKMQE 434
Query: 286 EKRKA------ILEARLAKLRQKKMKKSKEGGTEEENR 317
+++K + E + R+KKM++ +E E+E +
Sbjct: 435 QEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEK 472
Score = 45.4 bits (106), Expect = 1e-04
Identities = 60/301 (19%), Positives = 129/301 (42%), Gaps = 31/301 (10%)
Query: 16 VDLKAELFRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEE 75
++ K + K+ ++EK+ ++ + + K ++ + +Q + + EK EQ E
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQ---E 623
Query: 76 QKTLDKAREKLEEKAKLYEKMTKGDFIDEEV-EDMYLVDFTQKIIDKRKEMEASGAHRDS 134
+K ++ + E++ K++E+ K +E++ E L + +K+ + K E
Sbjct: 624 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQE 683
Query: 135 QKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQGRL 194
+K E++ E+ E E + +E + +S+ + MR++ + E ++ +Q +
Sbjct: 684 EKIWEQEKMEKKTQEQE---KKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQ- 739
Query: 195 FISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRENEARQLGVGYFAFA 254
EK E+ E + + WE+EE+ ++ + P E + E+E Q
Sbjct: 740 -----EEKMQEQEEEMWEQEEKMWEQEEKMWEQQRL-PEQKEKLWEHEKMQ--------- 784
Query: 255 RDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLRQKKMKKSKEGGTEE 314
+Q K E E+ DQ K +EK + E + + ++ K G EE
Sbjct: 785 -------EQEKIWEQ-EEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEE 836
Query: 315 E 315
+
Sbjct: 837 K 837
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 52.8 bits (125), Expect = 7e-07
Identities = 37/117 (31%), Positives = 66/117 (56%), Gaps = 11/117 (9%)
Query: 206 SEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQMK 265
SE++ LQ+++ +EEE E L+R + E R E + R KE ++MK
Sbjct: 906 SEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEK--------RRRKEEEERRMK 957
Query: 266 T-LEMLREQTTDQRTKRENIKEKRKAILEARLAKLRQKKMKKSKEGGTEEENRDGDV 321
+E R+Q ++R KRE+ +++ +A +EA+LA RQK+ + ++ E+E RD ++
Sbjct: 958 LEMEAKRKQEEEERKKREDDEKRIQAEVEAQLA--RQKEEESQQQAVLEQERRDREL 1012
Score = 29.6 bits (65), Expect = 6.1
Identities = 78/402 (19%), Positives = 154/402 (38%), Gaps = 68/402 (16%)
Query: 1 MDRRKKPLDVTASSLVDLKAELFRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVG 60
M+++ K L+++ +L+ QE+ ++E D+ V K++ + S K+
Sbjct: 867 MNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEY---DALV----KSSEELLSALQKKK-- 917
Query: 61 VSNRAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIID 120
+ E++AE+ Q+ ++K R++ EE K K +EE M L
Sbjct: 918 ---QQEEEAERLRRIQEEMEKERKRREEDEKRRRK-------EEEERRMKL--------- 958
Query: 121 KRKEMEASGAHRDSQKAGERDDDEENLP---EGEIPPPQDPSEEWVDYVDSLGRSRRCMR 177
EMEA + ++ +R+DDE+ + E ++ ++ + ++ R R
Sbjct: 959 ---EMEAKRKQEEEERK-KREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELAL 1014
Query: 178 KDLPDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYED 237
+ E+ + + A+ ++ R ++ +Q +E E L R + +
Sbjct: 1015 RIAQSEAELISD------EAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKA 1068
Query: 238 IRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLA 297
+ L +A RD + ++ L RE+ +R + A
Sbjct: 1069 AAGTKKYDLSKWKYAELRDTINTSCDIELLAACREEF-----------HRRLKVYHA--W 1115
Query: 298 KLRQKKMKKSKEGGTEEENRDGDVIGPLPPEPEAVPTPRPAAQSSKVEVIVQERKDTKPG 357
K + KK E + D D L P+ P + A+ ++E+ Q+R
Sbjct: 1116 KSKNKKRNTETEQRAPKSVTDYDFAPFLNNSPQQNPAAQIPARQREIEMNRQQRFFR--- 1172
Query: 358 VPHIREWDRGKE-----------FSFGYWSKRQSDLRAERDP 388
+P IR D+ K+ G W RQ +L ++ P
Sbjct: 1173 IPFIRPADQYKDPQSKKKGWWYAHFDGPWIARQMELHPDKPP 1214
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 52.4 bits (124), Expect = 9e-07
Identities = 71/341 (20%), Positives = 140/341 (41%), Gaps = 38/341 (11%)
Query: 19 KAELFRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQKT 78
K E R+QEE EK + K + +W K+ + ++KI EQ+
Sbjct: 347 KEEKMRRQEEMMWEK---------EEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEE 397
Query: 79 LDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAHRDSQKAG 138
+ EK+ E+ K E+ K +E++ + +KI ++ K+M +
Sbjct: 398 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQ-----EEKIREQEKKM---------WRQE 443
Query: 139 ERDDDEENLPEGEIPPPQDP---SEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQGRLF 195
E+ ++E + E E Q+ EE + + + R + M E +K +
Sbjct: 444 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMH-------EQEKIRKQEEK 496
Query: 196 ISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRENEARQLGVGYFAFAR 255
+ EK E+ +E + + W +EE+ + E IRE E +
Sbjct: 497 VWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQ 556
Query: 256 DKELRN--KQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLRQKK--MKKSKEGG 311
+++++ K + E +REQ R ++E I+E+ + I E K+R+++ M++ +E
Sbjct: 557 EEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE-EKIREQEEMMQEQEEKM 615
Query: 312 TEEENRDGDVIGPLPPEPEAVPTPRPAAQSSKVEVIVQERK 352
E+E + + + + E + +V + QE K
Sbjct: 616 WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 656
Score = 37.4 bits (85), Expect = 0.029
Identities = 29/109 (26%), Positives = 53/109 (48%), Gaps = 12/109 (11%)
Query: 210 RKELQRQQWEE---EEREALKRPMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQMKT 266
R+E + Q+WEE E+ E ++ E IRE E + + +++++R ++
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIRE-----QEEKIREQEEKMRRQEEMMWEKEEKMRRQE--- 355
Query: 267 LEMLREQTTDQRTKRENIKEKRKAILEARLAKLRQKKMKKSKEGGTEEE 315
EM+ E+ R E + EK + I E Q+K+++ +E EEE
Sbjct: 356 -EMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE 403
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 52.0 bits (123), Expect = 1e-06
Identities = 65/293 (22%), Positives = 126/293 (43%), Gaps = 30/293 (10%)
Query: 44 PKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQKTLDKAREKLEE-KAKLYEKMTKGDFI 102
P + K S K+ + N K+ +++ QK + R +LEE K K E++ K
Sbjct: 525 PLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQA 584
Query: 103 DEEVEDMY---LVDFTQKIIDKRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPS 159
E VE M QK ++ E + R +++ ++ + + E E Q+
Sbjct: 585 RERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE 644
Query: 160 EEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWE 219
+ ++ RR +LL+ K + A K L + ++ ++++ E
Sbjct: 645 ARRLRWLQQEEEERRHQ-----ELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERRE 699
Query: 220 EEEREALKRPMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRT 279
+E RE +R E R + RQL +++ ++++ L+E+ R
Sbjct: 700 QERREQERR-------EQERREQERQLA------EQERRREQERLQAERELQEREKALRL 746
Query: 280 KRENIK----EKRKAILEARLAK--LRQKKMKKSKE--GGTEEENRDGDVIGP 324
++E ++ EK+K + RLA+ L++++ KK+KE G ++ N DV P
Sbjct: 747 QKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSP 799
Score = 33.1 bits (74), Expect = 0.55
Identities = 42/196 (21%), Positives = 82/196 (41%), Gaps = 16/196 (8%)
Query: 122 RKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLP 181
R+ +++ R ++A D+E++L + E+ PP+ + + R R +
Sbjct: 441 REPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQ 500
Query: 182 --DLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIR 239
+L + + S T L D + + E+ER+ L+ R
Sbjct: 501 RNQMLMTPTSAPRSVMKSFIKRNTPLRMD-----PKCSFVEKERQRLENLR--------R 547
Query: 240 ENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKL 299
+ EA QL + + L ++K E LR + R + E +KE++K +E + A++
Sbjct: 548 KEEAEQLRRQKVEEDKRRRLEEVKLKREERLR-KVLQARERVEQMKEEKKKQIEQKFAQI 606
Query: 300 RQKKMKKSKEGGTEEE 315
+K K +E EE+
Sbjct: 607 DEKTEKAKEERLAEEK 622
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 51.2 bits (121), Expect = 2e-06
Identities = 75/362 (20%), Positives = 160/362 (44%), Gaps = 32/362 (8%)
Query: 1 MDRRKKPLDVTASSLVDLKAEL-----FRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWS 55
M R++K L L + + EL R+QEE QE+ ++ + K ++ +W
Sbjct: 278 MRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQ--EEKMWEQEEKMREQEEKMWR 335
Query: 56 KQNVGVSNRAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFT 115
++ E++ + + +EQK D+ E+ +L EK + ++ E +
Sbjct: 336 QEE----RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEE 391
Query: 116 QKIIDKRKEM-EASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRR 174
++I ++ K+M E R+ ++ ++ EEN+ E E Q + + + L +
Sbjct: 392 ERIREREKKMREEEETMREQEEKMQKQ--EENMWEQEEKEWQQ--QRLPEQKEKLWEQEK 447
Query: 175 CMRKDLPDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVH 234
M++ + E ++ ++ + + +K E MR++ + Q WE+EE+ +
Sbjct: 448 -MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ-EDQMWEQEEKMRDQEQKMWDQ 505
Query: 235 YEDIRENEARQLGVGYFAFARDKELRNKQMKTL----EMLREQTTDQRTKRENIKEKRKA 290
E + E + R R+KE R ++ K + E +RE+ Q +++ ++ K
Sbjct: 506 EERMWEQDER---------LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKM 556
Query: 291 ILEARLAKLRQKKMKKSKEGGTEEENRDGDVIGPLPPEPEAVPTPRPAAQSSKVEVIVQE 350
E R+ + R+KKM++ +E E+E + + + + E + Q + ++ QE
Sbjct: 557 REEERMRE-REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615
Query: 351 RK 352
K
Sbjct: 616 EK 617
Score = 48.1 bits (113), Expect = 2e-05
Identities = 54/266 (20%), Positives = 109/266 (40%), Gaps = 26/266 (9%)
Query: 56 KQNVGVSNRAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFT 115
K+N + + +K E Q + + + KLE L ++ +E +
Sbjct: 187 KKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQ 246
Query: 116 QKIIDKRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRC 175
+K I K++E R ++ G+ + EE + E L +
Sbjct: 247 EKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQE---------------KRLREQEKE 291
Query: 176 MRKDLPDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHY 235
+R+ +L E K + + EK E+ +E + + W +EER +
Sbjct: 292 LREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 351
Query: 236 EDIRENEARQLGVGYFAFARDKELRNKQ--MKTLEMLREQTTDQRTKRENIKEKRKAILE 293
+ +R+ E R + +D+ LR K+ M+ E + EQ ++ + E I+E+ K + E
Sbjct: 352 QKMRDQEERM-------WEQDERLREKEERMREQEKMWEQE-EKMQEEERIREREKKMRE 403
Query: 294 AR-LAKLRQKKMKKSKEGGTEEENRD 318
+ +++KM+K +E E+E ++
Sbjct: 404 EEETMREQEEKMQKQEENMWEQEEKE 429
Score = 47.0 bits (110), Expect = 4e-05
Identities = 52/277 (18%), Positives = 132/277 (47%), Gaps = 20/277 (7%)
Query: 19 KAELFRKQEE--FKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQ 76
+ E R+QE+ ++QE+ ++D + K +++ +W + + ++ E+++ EQ
Sbjct: 477 RQEKMREQEDQMWEQEEKMRDQ----EQKMWDQEERMWEQ------DERLREKEERMREQ 526
Query: 77 KTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAHRDSQK 136
K + + EK+ E+ K E+ K +E++ + + +K + + +EM + ++
Sbjct: 527 KKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ 586
Query: 137 AGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLL-EMDKNLQGRLF 195
+ + EE + E E + + W + ++ +++ E ++ +Q +
Sbjct: 587 EEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE 646
Query: 196 ISPANEKTL--LSEDMRKELQRQQWEEEE-REALKRPMGPVHYEDIRENEARQLGVGYFA 252
E+ + E MR++ ++ Q +EE+ RE ++ G E +RE E + G
Sbjct: 647 KMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQG--QEEKMREQEEKMRGQEEKM 704
Query: 253 FARDKEL--RNKQMKTLEMLREQTTDQRTKRENIKEK 287
+ +++++ + ++M E +RE+ R ++E ++E+
Sbjct: 705 WGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQER 741
Score = 45.1 bits (105), Expect = 1e-04
Identities = 63/309 (20%), Positives = 134/309 (43%), Gaps = 40/309 (12%)
Query: 21 ELFRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQKTLD 80
E +KQEE E+ K+ + + + +K +W ++ + + E+KI +Q+ +
Sbjct: 413 EKMQKQEENMWEQEEKE---WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW 469
Query: 81 KAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEM--------EASGAHR 132
+K+ + K+ E+ D + E+ E M D QK+ D+ + M E R
Sbjct: 470 GQEKKMWRQEKMREQE---DQMWEQEEKMR--DQEQKMWDQEERMWEQDERLREKEERMR 524
Query: 133 DSQKAGERDDD--EENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNL 190
+ +K ++++ EE + + D E+ + R ++ MR++ + E ++ +
Sbjct: 525 EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKK-MREEEEMMREQEEKM 583
Query: 191 QGRLF-ISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRENEARQLGVG 249
Q + + EK E+ +E + + WE+EE+ M ED + + +
Sbjct: 584 QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK------MWEQEEEDKMQEQEEMMW-- 635
Query: 250 YFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLRQKKMKKSKE 309
E K + E + EQ R + E ++E+ + ++ + K+R+++ K
Sbjct: 636 --------EQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK-MQGQEEKMREQEEKMQ-- 684
Query: 310 GGTEEENRD 318
G EE+ R+
Sbjct: 685 -GQEEKMRE 692
Score = 32.3 bits (72), Expect = 0.94
Identities = 38/227 (16%), Positives = 101/227 (44%), Gaps = 13/227 (5%)
Query: 1 MDRRKKPLDVTASSLVDLKAELFRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVG 60
M +KK + K + K+ ++EK+ ++ + + K ++ + +Q
Sbjct: 523 MREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK 582
Query: 61 VSNRAEKDAEQK---IEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQK 117
+ + EK EQ+ E+++ + + EK+ E+ + + + D + E+ E M+ + +K
Sbjct: 583 MQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMW--EQEEK 640
Query: 118 IIDKRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMR 177
+ ++ ++M Q+ R+ +E+ +G+ ++ E+ + + MR
Sbjct: 641 MQEQEEKMWEQEEKMREQEEKMREQEEK--MQGQEEKMREQEEKMQGQEEKMREQEEKMR 698
Query: 178 KDLPDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEERE 224
+ ++ + G+ EK E+MR++ +R + ++E+ +
Sbjct: 699 GQEEKMWGQEEKMWGQ------EEKMWGQEEMREKEERIRDQKEKMQ 739
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 51.2 bits (121), Expect = 2e-06
Identities = 82/397 (20%), Positives = 151/397 (38%), Gaps = 75/397 (18%)
Query: 66 EKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEM 125
E++ E++ E ++ ++ RE+ E+ K E+ + D+ +D +KR+E+
Sbjct: 757 ERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRR---------EKREEI 807
Query: 126 EASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLE 185
RD ER + EG P Q P DS + + + LL
Sbjct: 808 REDRNPRDGHD--ERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLS 865
Query: 186 MDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRENEARQ 245
Q +SP++ L+ED ++ +W+EE+R+ P E R E ++
Sbjct: 866 QVVRPQESRSLSPSH----LTED-----RQGRWKEEDRK-------PERKESSRRYEEQE 909
Query: 246 LGVGYFAFARDKE----LRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLRQ 301
L + + +E L + +M+ +++ ++ R + ++ K + AK+++
Sbjct: 910 LKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENK-----KKAKIQK 964
Query: 302 KKMKKSKE-------GGTEEENRDGDVIGPLP-PEPEAVPTPRPAAQS----SKVEVIVQ 349
K +KK KE G E + DG V P + +++ R ++ S E Q
Sbjct: 965 KPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQ 1024
Query: 350 ERKDTKPGVPHIREWDRGKEFSFGYWSKRQSDLRAERDPEFAPPSDYFVGQKRTGFSSSQ 409
+K P P I + E G + D + + D F+ SD V
Sbjct: 1025 SKKKRGPRTPPITTKEELVEMCNGK-NGILEDSQKKEDTAFSDWSDEDV----------- 1072
Query: 410 AWSRPGPAQSDPGQCPDQSHGPSPEHTSPTPAPDNPP 446
PD++ EHT+ P + P
Sbjct: 1073 ---------------PDRTEVTEAEHTATATTPGSTP 1094
Score = 35.8 bits (81), Expect = 0.085
Identities = 49/221 (22%), Positives = 90/221 (40%), Gaps = 26/221 (11%)
Query: 182 DLLEMDKNLQGRLF--ISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIR 239
D LE D+ + R + ++ D +E R++ E ERE + E R
Sbjct: 652 DELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDRER------EKER 705
Query: 240 ENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKL 299
E E + AR++E ++ + E R++ D+ +RE +++ K R +
Sbjct: 706 ELERER--------AREREREREKERDRERDRDRDHDRERERERERDREKEREREREERE 757
Query: 300 RQKKMKKSKEGGTEEEN---RDGDVIGPLPPEPEAVPTPRPAAQSSKVEVIVQERKDTKP 356
R+++ ++ +E E E R+ D + E R + + E+ R+D P
Sbjct: 758 RERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEI----REDRNP 813
Query: 357 GVPHIREWDRGKEFSFGYWSKRQSDLRAERDPEFAPPSDYF 397
H + + + G S RQS +R E +P SD +
Sbjct: 814 RDGHDERKSKKRYRNEGSPSPRQS---PKRRREHSPDSDAY 851
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 50.4 bits (119), Expect = 3e-06
Identities = 68/339 (20%), Positives = 139/339 (41%), Gaps = 39/339 (11%)
Query: 19 KAELFRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQKT 78
K E R+QEE EK + K ++ +W K+ + ++KI EQ+
Sbjct: 408 KEEKMRRQEEMMWEK---------EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 458
Query: 79 LDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAHRDSQKAG 138
+ EK+ E+ K E+ K +E++ + +KI ++ ++M +
Sbjct: 459 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQ-----EEKIREQEEKM---------WRQE 504
Query: 139 ERDDDEENLPEGEIPPPQDP---SEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQGRLF 195
E+ ++E + E E Q+ EE + + + R + + + + + ++ + +
Sbjct: 505 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQ-- 562
Query: 196 ISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRENEARQLGVGYFAFAR 255
EK E+ +E + + W +EE+ + E IRE E + +
Sbjct: 563 ----EEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE----MTQEQEEK 614
Query: 256 DKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLRQKK--MKKSKEGGTE 313
E K + E ++EQ R + E I+E+ K I E K+R+++ M++ +E E
Sbjct: 615 MGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQE-EKIREQEEMMQEQEEKMWE 673
Query: 314 EENRDGDVIGPLPPEPEAVPTPRPAAQSSKVEVIVQERK 352
+E + + + + E + +V + QE K
Sbjct: 674 QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 712
Score = 38.5 bits (88), Expect = 0.013
Identities = 29/109 (26%), Positives = 54/109 (49%), Gaps = 12/109 (11%)
Query: 210 RKELQRQQWEE---EEREALKRPMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQMKT 266
R+E + Q+WEE E+ E ++ E IRE E + + +++++R ++
Sbjct: 365 RQEEKIQEWEEKIQEQEEKIRE-----QEEKIREQEEKMRRQEEMMWEKEEKMRRQE--- 416
Query: 267 LEMLREQTTDQRTKRENIKEKRKAILEARLAKLRQKKMKKSKEGGTEEE 315
EM+ E+ R + E + EK + I E Q+K+++ +E EEE
Sbjct: 417 -EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE 464
Score = 34.7 bits (78), Expect = 0.19
Identities = 45/241 (18%), Positives = 108/241 (44%), Gaps = 26/241 (10%)
Query: 84 EKLEEK-AKLYEKM----TKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAHRDSQKAG 138
E+L+EK AKL EK+ ++ I V+++ K++ +++++A H +
Sbjct: 278 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 337
Query: 139 ERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQGRLFISP 198
+ + E E+ + +E + + R +++ + E ++ ++ +
Sbjct: 338 VSAKLQAQVEENELWNRLNQQQE-----EKMWRQEEKIQEWEEKIQEQEEKIREQ----- 387
Query: 199 ANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRENEARQLGVGYFAFARDKE 258
EK E+ + + WE+EE+ + M E +R E + ++++
Sbjct: 388 -EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE-------MMWEKEEK 439
Query: 259 LR--NKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLRQKKMKKSKEGGTEEEN 316
+R ++M E +REQ ++R + E I+E+ K + +++K+++ +E E+E
Sbjct: 440 IRELEEKMHEQEKIREQ-EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE 498
Query: 317 R 317
+
Sbjct: 499 K 499
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 50.4 bits (119), Expect = 3e-06
Identities = 68/314 (21%), Positives = 120/314 (38%), Gaps = 47/314 (14%)
Query: 19 KAELFRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSK-QNVGVSNRAEKDAEQKIEEQK 77
K E+ KQ+E K ++ DS PK ++ K K Q + + N+ + E +++E
Sbjct: 523 KQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDE-- 580
Query: 78 TLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAHRDSQKA 137
L + ++ EE L E++T+G E L + + ++ ++
Sbjct: 581 ILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECR 640
Query: 138 GERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLP---------------- 181
RD+ E L E+ D ++ + MRK+L
Sbjct: 641 KLRDEKETLLQR------LTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASL 694
Query: 182 -----DLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWE--------EEEREALKR 228
DL + L+ RL + A E L E++ K + Q E E+ER+ALK
Sbjct: 695 QQTQGDLSAYEAELEARLNLRDA-EANQLKEELEKVTRLTQLEQSALQAELEKERQALKN 753
Query: 229 PMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKR 288
+G + + +E E +L D L +Q+K + D + E +
Sbjct: 754 ALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEV---- 809
Query: 289 KAILEARLAKLRQK 302
AR+ +LR+K
Sbjct: 810 ----AARVDELRRK 819
Score = 37.7 bits (86), Expect = 0.022
Identities = 63/324 (19%), Positives = 138/324 (42%), Gaps = 55/324 (16%)
Query: 2 DRRKKPLDVTASSLVDLKAELFRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGV 61
D+R L+ T ++++ K EL Q+ +Q+K G+ + W KQ +
Sbjct: 1720 DQRVSELEKTQVAVLEEKLELENLQQISQQQK--------GEIE--------WQKQ---L 1760
Query: 62 SNRAEKDAEQKIEEQKTLD-------KAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDF 114
R +++ E+ E + L K +E L+EK ++EK + + + +
Sbjct: 1761 LERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKK-----LAQTKRVLAAAEE 1815
Query: 115 TQKIIDKRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRR 174
K+ E + Q+ + + D+ +L +I Q +E + V+SL
Sbjct: 1816 NSKMEQSNLEKLELNVRKLQQELDQLNRDKLSL-HNDISAMQQQLQEKREAVNSL----- 1869
Query: 175 CMRKDLPDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEE-----EEREALKRP 229
+++L ++ + + L + ++ LLSE R + +W ++ E K+
Sbjct: 1870 --QEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQ 1927
Query: 230 MGPVHYEDIRENEAR--QLGVGYFAFARDKELRNKQMKTLEM--------LREQTTDQRT 279
V +I EN+ + Q + + +++E +++T ++ L ++ TDQ++
Sbjct: 1928 QLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKS 1987
Query: 280 KRENIKEKRKAILEARLAKLRQKK 303
K + + K A E R+ L++++
Sbjct: 1988 KLDQVLSKVLA-AEERVRTLQEEE 2010
Score = 30.4 bits (67), Expect = 3.6
Identities = 15/57 (26%), Positives = 30/57 (52%)
Query: 42 GKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTK 98
G+P TT + + + ++ R E+D E+K+ E + L + + E+ K +K+ K
Sbjct: 252 GQPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNK 308
>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
Length = 1233
Score = 50.1 bits (118), Expect = 4e-06
Identities = 48/181 (26%), Positives = 82/181 (45%), Gaps = 22/181 (12%)
Query: 199 ANEKTLLSEDMRKELQRQQWEEEEREALKRPMG-----PVHYEDI-RENEARQLGVGYF- 251
A EK L E + L+R+ WEE R+ L G P+ E RE + R L +
Sbjct: 242 AAEKRRLEEQRLQALERRLWEENRRQELLEEEGEGQEPPLEAERAPREEQQRSLEAPGWE 301
Query: 252 -AFARDKELRNKQMKTLEMLREQTTDQRTKRENIKE-------KRKAILEARLAKLRQKK 303
A R++E R + E R Q Q +R ++E +R+ E R A+ +++
Sbjct: 302 DAERREREERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQ 361
Query: 304 MKKSKEGGTEEENRDGDVIGPLPPEPEAVPTPRPAAQSSKVEVIVQERKDTKPGVPHIRE 363
++ EG E E ++ +V GP PEA+ + ++ E + +E ++ G H+ +
Sbjct: 362 EEEEAEGWEELEQQEAEVQGP----PEALEETGEGRRGAEEEDLGEEEEE---GQAHLED 414
Query: 364 W 364
W
Sbjct: 415 W 415
Score = 32.3 bits (72), Expect = 0.94
Identities = 52/231 (22%), Positives = 98/231 (42%), Gaps = 42/231 (18%)
Query: 64 RAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRK 123
+A+ + +++EE L++ R + EE+ + E++ + + +EE E ++ ++
Sbjct: 326 QAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQE--EEEAEGWEELE--------QQ 375
Query: 124 EMEASGAHRDSQKAGE--RDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLP 181
E E G ++ GE R +EE+L E E Q E+W R L
Sbjct: 376 EAEVQGPPEALEETGEGRRGAEEEDLGEEE-EEGQAHLEDW--------------RGQLS 420
Query: 182 DLL-EMDKNLQGRLFISPA-----NEKTLLSEDMRKELQR---QQWEEEEREALKRPMGP 232
+LL + ++ L+ + + P +E+ + E+ E +R QQ + + RP GP
Sbjct: 421 ELLNDFEERLEDQERLKPEGQREHSEEPGICEEQNPEAERRREQQGRSGDFQGADRP-GP 479
Query: 233 VHYEDIRENEARQLGVGYFAFA-----RDKELRNKQMKTLEMLREQTTDQR 278
+ + E G A R + +Q + +E LR Q D+R
Sbjct: 480 EEKREEGDTEPLLKQEGPVEAAQPPVERKEAAALEQGRKVEELRWQEVDER 530
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 50.1 bits (118), Expect = 4e-06
Identities = 57/266 (21%), Positives = 123/266 (46%), Gaps = 22/266 (8%)
Query: 64 RAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDK-- 121
RAE++ + K+EEQK + ++ E+K + E KG+ +++++E + V+ + DK
Sbjct: 374 RAEEEEKAKVEEQK---RNKQLEEKKHAMQETKIKGEKVEQKIEGKW-VNEKKAQEDKLQ 429
Query: 122 ----RKEMEASGAHRDSQKAGERDD----DEENLPEGEIPPPQDPSEEWVDYVDSLGRSR 173
+K+ E G +++ ++D +E + + +I ++P EE ++D
Sbjct: 430 TAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFT 489
Query: 174 RCMRKDLPDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEER-EALKRPMGP 232
++ + K+ + F P S D ++ Q E +R E L+R G
Sbjct: 490 EVKSQNGEFMTHKLKHTE-NTFSRPGGR---ASVDTKEAEGAPQVEAGKRLEELRRRRGE 545
Query: 233 VHYEDIRENEARQ--LGVGYFAFARDKELRNKQMKTLEMLREQ-TTDQRTKRENIKEKRK 289
E+ + + +Q + + +E R K ++ E R+Q D++ + E K + K
Sbjct: 546 TESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLK 605
Query: 290 AILEARLAKLRQKKMKKSKEGGTEEE 315
+E R A+ +K+ K ++G ++++
Sbjct: 606 EEIERRRAEAAEKRQKMPEDGLSDDK 631
Score = 44.7 bits (104), Expect = 2e-04
Identities = 73/301 (24%), Positives = 131/301 (43%), Gaps = 37/301 (12%)
Query: 21 ELFRKQEEFKQEKL---LKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQK 77
E ++EE +Q++L L+ F P T+ S+ S++ ++ AE + +K EE+
Sbjct: 98 ERLARREERRQKRLQEALERQKEFD-PTITDASLSLPSRRMQ--NDTAENETTEK-EEKS 153
Query: 78 TLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAHRDSQKA 137
+ R ++EE + + K D+ D E K DK KE E ++
Sbjct: 154 ESRQERYEIEETETVTKSYQKNDWRDAE---------ENKKEDKEKEEE-------EEEK 197
Query: 138 GERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQGRLFIS 197
+R EN E + S+E +++ S + + + + ++ QG IS
Sbjct: 198 PKRGSIGENQVEVMVEEKTTESQE-----ETVVMSLKNGQISSEEPKQEEEREQGSDEIS 252
Query: 198 PANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRENEARQLGVGYFAFARDK 257
+EK + R E +R + E EERE +K ++ EA + A A+++
Sbjct: 253 H-HEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEK-----AAAQER 306
Query: 258 ELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEAR-LAKLRQKKMKKSKEGGTEEEN 316
E R + + E +RE+ +R+ IKE+ K E R K +K+ + ++ EEE
Sbjct: 307 ERREAEER--ERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEK 364
Query: 317 R 317
R
Sbjct: 365 R 365
Score = 42.4 bits (98), Expect = 0.001
Identities = 55/252 (21%), Positives = 107/252 (42%), Gaps = 15/252 (5%)
Query: 61 VSNRAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIID 120
V+ +K+ + EE K DK +E+ EE EK +G + +VE M +K +
Sbjct: 168 VTKSYQKNDWRDAEENKKEDKEKEEEEE-----EKPKRGSIGENQVEVMV----EEKTTE 218
Query: 121 KRKEMEASGAHRDSQKAGERDDDEENLPEG--EIPPPQDPSEEWVDYVDSLGRSRRCMRK 178
++E ++ Q + E EE +G EI + EE + ++ R+R +
Sbjct: 219 SQEETVVMSL-KNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEA-ERARLEAEE 276
Query: 179 DLPDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQ-RQQWEEEEREALKRPMGPVHYED 237
E DK + A EK E R+E + R++ EEE+ A + E
Sbjct: 277 RERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEK 336
Query: 238 IRENEARQLGVGYFAFARDKE-LRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARL 296
E +++ A +++ ++ ++ + E + ++ K + ++KR LE +
Sbjct: 337 RAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKK 396
Query: 297 AKLRQKKMKKSK 308
+++ K+K K
Sbjct: 397 HAMQETKIKGEK 408
Score = 29.3 bits (64), Expect = 8.0
Identities = 16/55 (29%), Positives = 30/55 (54%)
Query: 253 FARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLRQKKMKKS 307
F R +ELR ++ + + + E+ QR + + R+ AR +LRQK+ ++S
Sbjct: 4 FERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEES 58
>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
sapiens]
Length = 551
Score = 50.1 bits (118), Expect = 4e-06
Identities = 71/308 (23%), Positives = 129/308 (41%), Gaps = 68/308 (22%)
Query: 13 SSLVDLKAELFRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQK 72
+S V + EL + + FK+EK V + K +K +W+ +N+ D E+
Sbjct: 115 ASHVLTREELEARDQAFKKEKEATMDAVMTRKKIMKQKEMVWN------NNKKLSDLEEV 168
Query: 73 IEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAHR 132
+E +A+ L+ KL + +EE++DM KII K A R
Sbjct: 169 AKE-----RAQNLLQRANKLRMEQ------EEELKDM------SKIILNAK----CHAIR 207
Query: 133 DSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQG 192
D+Q L + +I D E+ +D + + R + R++ + ++ ++G
Sbjct: 208 DAQ----------ILEKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELERKRREERIRG 257
Query: 193 RLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRENEARQLGVGYFA 252
R I EK +++ R L Q+ E+E+E + M + ED+++ E RQ
Sbjct: 258 RRQIVEQMEK---NQEERSLLAEQR--EQEKEQMLEYMEQLQEEDLKDMERRQ------- 305
Query: 253 FARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLA-----KLRQKKMKKS 307
+ L+ Q +R EN K+K + + + +LA + +KKM +
Sbjct: 306 --------------QQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMARE 351
Query: 308 KEGGTEEE 315
E E+E
Sbjct: 352 AEFEAEQE 359
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 49.7 bits (117), Expect = 6e-06
Identities = 64/318 (20%), Positives = 138/318 (43%), Gaps = 46/318 (14%)
Query: 24 RKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQKTLDKAR 83
R++++ ++E+ L+ + + ++ + +Q + + ++ + + E+Q ++
Sbjct: 372 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEE 431
Query: 84 EKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAHRDSQKAGERDDD 143
E+ E+K +E+ + + E E+ + + + +E E R Q+ +RD +
Sbjct: 432 ERHEQK---HEQERREQRLKREQEER------RDWLKREEETERHEQERRKQQL-KRDQE 481
Query: 144 EEN------LPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQGRL--- 194
EE L E E Q+ E+ + R +R R++ + L+ + +L
Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541
Query: 195 -------FISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRENEARQLG 247
+ EK L E + L+R+Q EE + LKR RE E R
Sbjct: 542 QEERREQLLKREEEKRLEQERREQRLKREQ-EERRDQLLKREEERRQQRLKREQEERL-- 598
Query: 248 VGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAIL-------EARLAKLR 300
++ L+ ++++ LE +E+ +QR KRE +E+R+ L E R +LR
Sbjct: 599 --------EQRLKREEVERLE--QEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLR 648
Query: 301 QKKMKKSKEGGTEEENRD 318
+++ ++ ++ EE +
Sbjct: 649 REQQERREQRLKREEEEE 666
Score = 47.0 bits (110), Expect = 4e-05
Identities = 50/252 (19%), Positives = 117/252 (46%), Gaps = 26/252 (10%)
Query: 66 EKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEM 125
++ +++ E+++ L + E+ E++ +L ++ D + D L Q+ +R+E
Sbjct: 135 QRRRQKRQEQERELAEGEEQSEKQERLEQR-------DRQRRDEELWRQRQEW-QEREER 186
Query: 126 EASGAHRDSQKAGERDD--DEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDL 183
A S K E ++ DEE L E+ + E + +R R+D
Sbjct: 187 RAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEK-------QQQRRERQDRVFQ 239
Query: 184 LEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRENEA 243
E +K + R + E+ L E+ +++ + Q+ EE+ R+ ++ + E+ ++ +
Sbjct: 240 EEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQR 299
Query: 244 RQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLRQKK 303
+ R+++LR KQ + +E+ +Q+ +RE +E+R+ L + R+++
Sbjct: 300 LR---------REQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQ 350
Query: 304 MKKSKEGGTEEE 315
+++ +E E+
Sbjct: 351 LRREQEEERREQ 362
Score = 43.9 bits (102), Expect = 3e-04
Identities = 56/301 (18%), Positives = 129/301 (42%), Gaps = 27/301 (8%)
Query: 25 KQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQKTLDKARE 84
+QEE ++++L ++ + + ++ +Q + E+ +Q EQ+ + +
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
Query: 85 KLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAHRDSQKAGERDDDE 144
+ E++ + +++ + + E Q++ +++ R+ ++ E
Sbjct: 390 RREQQLRREQQLRREQQLRRE----------QQLRREQQLRREQQLRREQEEERHEQKHE 439
Query: 145 ENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQGRLFISPANEKTL 204
+ E + Q+ +W+ + R + RK L+ D+ + R E+
Sbjct: 440 QERREQRLKREQEERRDWLKREEETERHEQERRKQQ---LKRDQEEERRERWLKLEEEER 496
Query: 205 LSEDMRKELQRQQWEEEEREA-LKRPMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQ 263
+ R+E Q ++ +EE RE LKR + +E + R++E R +Q
Sbjct: 497 REQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQ--------LRREQEERREQ 548
Query: 264 MKTLE---MLREQTTDQRTKRENIKEKRKAILEARLAKLRQKKMKKSKEGGTEEENRDGD 320
+ E L ++ +QR KRE +E+R+ L R + RQ+++K+ +E E+ + +
Sbjct: 549 LLKREEEKRLEQERREQRLKRE--QEERRDQLLKREEERRQQRLKREQEERLEQRLKREE 606
Query: 321 V 321
V
Sbjct: 607 V 607
Score = 42.4 bits (98), Expect = 0.001
Identities = 70/331 (21%), Positives = 142/331 (42%), Gaps = 59/331 (17%)
Query: 18 LKAELFRKQEEFKQEKLLKDSGVFGKPKTTN-------------KKPSIWSKQNVGVSNR 64
+K+ + + Q + + E + S V+ +P+ ++ S Q ++R
Sbjct: 697 IKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHR 756
Query: 65 AEKDAEQKIE-------EQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQK 117
+++ EQ+ + E+K+ ++ R++L + L E+ + +E + Q+
Sbjct: 757 QQQEEEQRRDFTWQWQAEEKS-ERGRQRLSARPPLREQRERQLRAEERQQR------EQR 809
Query: 118 IIDKRKEMEASGAHR-DSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCM 176
+ + +E E R + +K + ++EE L E E+ + RS+
Sbjct: 810 FLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE-Q 868
Query: 177 RKDLP---DLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPV 233
R+D L E K + L+ PA L E +RKE Q Q EEEE + +R
Sbjct: 869 RRDQKWRWQLEEERKRRRHTLYAKPA-----LQEQLRKEQQLLQEEEEELQREERE---- 919
Query: 234 HYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRE-----NIKEKR 288
+ R+ + RQ + +++L+ ++ + L RE+ Q +R+ +++K
Sbjct: 920 --KRRRQEQERQ-------YREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKE 970
Query: 289 KAIL----EARLAKLRQKKMKKSKEGGTEEE 315
+ +L E R + R+KK ++ +E EEE
Sbjct: 971 EQLLGEEPEKRRRQEREKKYREEEELQQEEE 1001
Score = 42.4 bits (98), Expect = 0.001
Identities = 68/308 (22%), Positives = 128/308 (41%), Gaps = 60/308 (19%)
Query: 3 RRKKPLDVTASSLVDLKAELFRKQEEFK----QEKLLKDSGVFGKPKTTNKKPSIWSKQN 58
R+ K L L+ + E R+QE K +E+L ++ + + ++ W +Q
Sbjct: 961 RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQY 1020
Query: 59 VGVSNRAEKDAEQKIEEQKTLDKAREK--LEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQ 116
K E + EE++ L + REK L+E+ + Y + +EE++ + Q
Sbjct: 1021 -------RKKDELQQEEEQLLREEREKRRLQERERQYRE-------EEELQQ----EEEQ 1062
Query: 117 KIIDKRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRC- 175
+ ++R+ R +K E +EE L E P + +E R R+C
Sbjct: 1063 LLGEERETRRRQELERQYRKEEELQQEEEQLLREE--PEKRRRQE---------RERQCR 1111
Query: 176 ----MRKDLPDLLEMDKNLQGRLFIS---------PANEKTLLSED----MRKELQRQQW 218
++++ LL ++ + R + E+ LL E+ R+EL+RQ
Sbjct: 1112 EEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYR 1171
Query: 219 EEEEREALKRPMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQR 278
EEEE + + + E R+ RQ + ++EL+ ++ K +Q +D +
Sbjct: 1172 EEEELQQEEEQLLREEQEKRRQERERQ-------YREEEELQRQKRKQRYRDEDQRSDLK 1224
Query: 279 TKRENIKE 286
+ E KE
Sbjct: 1225 WQWEPEKE 1232
Score = 41.2 bits (95), Expect = 0.002
Identities = 60/318 (18%), Positives = 137/318 (43%), Gaps = 42/318 (13%)
Query: 19 KAELFRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQKT 78
K +L R QEE ++E+ LK + + ++ + +Q E+ EQ+++ Q+
Sbjct: 473 KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQ--------EERREQRLKRQEE 524
Query: 79 LDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAH---RDSQ 135
++ +++L + +L + +E E + + +++ +R+E RD
Sbjct: 525 EERLQQRLRSEQQLRREQ------EERREQLLKREEEKRLEQERREQRLKREQEERRDQL 578
Query: 136 KAGERDDDEENLP-EGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQGRL 194
E + ++ L E E Q E V+ ++ R + ++++ P+ + + +L
Sbjct: 579 LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE-----EERRQQL 633
Query: 195 FISPANEKTLLSEDMRKELQRQQWE---EEEREALKRPMGPVHYEDIRENEARQ------ 245
S E+ + R++ +R++ EEE E L++ + H E+ RE E +
Sbjct: 634 LKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQA 693
Query: 246 -----LGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLR 300
+ + + + E +Q K R+Q +R + + K +R+ E+ L
Sbjct: 694 RERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRR---ESELQWQE 750
Query: 301 QKKMKKSKEGGTEEENRD 318
+++ + ++ EE+ RD
Sbjct: 751 EERAHRQQQ--EEEQRRD 766
Score = 40.0 bits (92), Expect = 0.005
Identities = 64/318 (20%), Positives = 146/318 (45%), Gaps = 48/318 (15%)
Query: 23 FRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQKTLDKA 82
+R++EE +QE+ + ++P +Q + R E++ +Q+ EEQ ++
Sbjct: 1140 YREEEEVQQEE----------EQLLREEPEKRRRQELERQYREEEELQQE-EEQLLREEQ 1188
Query: 83 REKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAHRDSQK--AGER 140
++ +E+ + Y + + + ++ + Y + + + + E E A RD++ G
Sbjct: 1189 EKRRQERERQYRE--EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE 1246
Query: 141 DDDEENLPEGEIPPPQDPSEEWVDYV-------DSLGRSRRCMRKD--LPDLLEMDKNLQ 191
++ L + ++ Q S++ + ++ D RR ++D P+ ++++ Q
Sbjct: 1247 NEQFRQLEDSQLRDRQ--SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304
Query: 192 G---RLFISPANEKTLLSEDMRKELQRQQ----WEEEEREALKRPMGPVHYEDIRENEAR 244
R EK LL E+ ++ +RQ+ + EEE+ +R P+ R+ R
Sbjct: 1305 KEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR----RQERDR 1360
Query: 245 QLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKREN--IKEKRKAILEARLAKLRQK 302
+ R++ELR+++ + L E+ +R +RE +KE+++ + R +LRQ
Sbjct: 1361 KF--------REEELRHQEQGR-KFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQD 1411
Query: 303 KMKKSKEGGTEEENRDGD 320
+ +K +E + ++ D
Sbjct: 1412 RDRKFREEEQQLSRQERD 1429
Score = 40.0 bits (92), Expect = 0.005
Identities = 83/428 (19%), Positives = 180/428 (42%), Gaps = 51/428 (11%)
Query: 18 LKAELFRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQK 77
L+ E RK E +E+LL++ + + + +Q + R E+D + + +E +
Sbjct: 1455 LRQERHRKFRE--EEQLLQEREEQQLHRQERDRKFLEEEQQL---RRQERDRKFREQELR 1509
Query: 78 TLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIID---KRKEMEASGAHRDS 134
+ + R+ LEE+ +L+ + + F+ EE + Q+ D K +E E R+
Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE 1569
Query: 135 QKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSR----------RCMRKDLPDLL 184
Q+ ++ D + E + Q+ ++++ L R R R+D L
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629
Query: 185 E-----MDKNLQGRLFI--SPANEKTLLSEDMRKELQRQQWEEE------EREALKRPMG 231
E + + + R F+ P + + +R + R+ EEE E + L+R
Sbjct: 1630 EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQER 1689
Query: 232 PVHYEDIRENEARQLGVGYFAFARDKELRNKQM----KTLEMLREQTTDQRTKRENIKEK 287
+ + + RQ F +++LR +++ + E LR++T ++ +R+ +
Sbjct: 1690 DRKFREEEQQLRRQERERKF-LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQ--ERY 1746
Query: 288 RKAILEARLAKLRQ----KKMKKSKEGGTEEENRDGDVIGPLPPEPEAVPTPRPAAQSSK 343
RK + E +L R+ ++ ++ ++ EE+ R E + + + + +
Sbjct: 1747 RKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQ-------EREEQQLRSQESDRKFRE 1799
Query: 344 VEVIVQERKDTKPGVPHIREWDRGKEFSFGYWSKRQSDLRAERDPEFAPPSDYFVGQKRT 403
E + QER++ + P R+ E +++ LR ERD ++ + F Q+++
Sbjct: 1800 EEQLRQEREEQQLR-PQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR-AEEQFATQEKS 1857
Query: 404 GFSSSQAW 411
+ W
Sbjct: 1858 RREEQELW 1865
Score = 38.1 bits (87), Expect = 0.017
Identities = 55/304 (18%), Positives = 129/304 (42%), Gaps = 26/304 (8%)
Query: 24 RKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKI----EEQKTL 79
R++EE +Q++L ++ + K + ++ ++ + E+ EQ++ EE++
Sbjct: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQ 349
Query: 80 DKAREKLEEKAKLY-EKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAHRDSQKAG 138
RE+ EE+ + + + + ++++ + Q++ +++ R+ Q
Sbjct: 350 QLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 409
Query: 139 ERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQGRLFISP 198
E+ E E ++ EE + R + ++++ + + K +
Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQ 469
Query: 199 ANEKTLLSEDMRKELQRQQW----EEEEREALKRPMGPVHYEDIRENEARQLGVGYFAFA 254
K L D +E +R++W EEE RE +R + RE E R
Sbjct: 470 ERRKQQLKRDQEEE-RRERWLKLEEEERREQQERREQQLR----REQEER---------- 514
Query: 255 RDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLRQKKMKKSKEGGTEE 314
+E R K+ + E L+++ ++ R +E+R+ +L+ K +++ ++ + +E
Sbjct: 515 --REQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQE 572
Query: 315 ENRD 318
E RD
Sbjct: 573 ERRD 576
Score = 36.6 bits (83), Expect = 0.050
Identities = 48/267 (17%), Positives = 120/267 (44%), Gaps = 23/267 (8%)
Query: 64 RAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEV-------EDMYLVDFTQ 116
R E+D + + EE + ++ R+ LEE+ +L + + F+ EE E D +
Sbjct: 1355 RQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDR 1414
Query: 117 KIIDKRKEM---EASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSL-GRS 172
K ++ +++ E R+ ++ R + E E E Q+ ++ + L R
Sbjct: 1415 KFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQERE 1474
Query: 173 RRCMRKDLPDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGP 232
+ + + D +++ Q R ++ +++R + +++ EEE++ ++
Sbjct: 1475 EQQLHRQERDRKFLEEEQQLR---RQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR 1531
Query: 233 VHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAIL 292
++ ++ ++ G + ++ R+++ + E LR++ +Q+ R+ + RK L
Sbjct: 1532 KFLQEEQQLRRQERG------QQRRQDRDRKFREEEQLRQEREEQQLSRQ--ERDRKFRL 1583
Query: 293 EARLAKLRQKKMKKSKEGGTEEENRDG 319
E + + RQ++ +K E + ++G
Sbjct: 1584 EEQKVR-RQEQERKFMEDEQQLRRQEG 1609
Score = 32.7 bits (73), Expect = 0.72
Identities = 52/271 (19%), Positives = 117/271 (43%), Gaps = 33/271 (12%)
Query: 50 KPSIWSKQNVGVSNRAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDM 109
K S+ + R + ++++EE+ + +++ E++ +L E G+ E+ E +
Sbjct: 106 KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAE----GEEQSEKQERL 161
Query: 110 YLVDFTQKIIDKRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQD-PSEEWVDYVDS 168
D +R++ E ++ Q+ ER +EE L + ++ P EE + +
Sbjct: 162 EQRD------RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRREL 215
Query: 169 LGRSRRCMRKDLPDLLEMDKNLQGRLFISPANEKTLLSED-MRKELQRQQWEEEEREALK 227
L RK + + + Q R+F ++ E +RKE ++ Q EE +R+
Sbjct: 216 L----ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQREL 271
Query: 228 RPMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEK 287
+ E + R+L +ELR ++ + + + +Q+ +R+ +E+
Sbjct: 272 QE---------EEEQLRKL--------ERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314
Query: 288 RKAILEARLAKLRQKKMKKSKEGGTEEENRD 318
R+ E R + R+++ ++ +E E +
Sbjct: 315 REQQEERREQQERREQQEERREQQLRREQEE 345
Score = 32.3 bits (72), Expect = 0.94
Identities = 47/219 (21%), Positives = 94/219 (42%), Gaps = 22/219 (10%)
Query: 64 RAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRK 123
R E + + + EEQ + +E+L + + Y K+ + + + E E+ L Q+ K +
Sbjct: 1718 RQELERKFREEEQLRQETEQEQLRRQER-YRKILEEEQLRPEREEQQLR--RQERDRKFR 1774
Query: 124 EMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGR--SRRCMRKDLP 181
E E R+ Q+ ++ D + E ++ ++ + D R + ++
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE 1834
Query: 182 DLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEE---REALKRPMGPVHYEDI 238
L +++ Q R A E+ E R+E +++ W+EEE R+ +R + H
Sbjct: 1835 QRLRQERDRQYR-----AEEQFATQEKSRRE-EQELWQEEEQKRRQERERKLREEHIRRQ 1888
Query: 239 RENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQ 277
++ E R VG E+++++ K L E T Q
Sbjct: 1889 QKEEQRHRQVG--------EIKSQEGKGHGRLLEPGTHQ 1919
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 49.7 bits (117), Expect = 6e-06
Identities = 62/281 (22%), Positives = 122/281 (43%), Gaps = 30/281 (10%)
Query: 56 KQNVGVSNRAEKDAEQKIEEQKTLDKAREKLEE-KAKLYEKMTKGDFIDEEVEDMY---L 111
K+ + N K+ +++ QK + R +LEE K K E++ K E VE M
Sbjct: 533 KERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKK 592
Query: 112 VDFTQKIIDKRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGR 171
QK ++ E + R +++ ++ + + E E Q+ + ++
Sbjct: 593 KQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE 652
Query: 172 SRRCMRKDLPDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMG 231
RR +LL+ K + A K L + ++ ++++ E+E RE +R
Sbjct: 653 ERRHQ-----ELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERR--- 704
Query: 232 PVHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIK----EK 287
E R + RQL +++ ++++ L+E+ R ++E ++ EK
Sbjct: 705 ----EQERREQERQLA------EQERRREQERLQAERELQEREKALRLQKEQLQRELEEK 754
Query: 288 RKAILEARLAK--LRQKKMKKSKE--GGTEEENRDGDVIGP 324
+K + RLA+ L++++ KK+KE G ++ N DV P
Sbjct: 755 KKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSP 795
Score = 37.0 bits (84), Expect = 0.038
Identities = 43/194 (22%), Positives = 82/194 (42%), Gaps = 16/194 (8%)
Query: 122 RKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLP 181
R+ +++ R ++A D+E++L + E+ PP+ + + R R
Sbjct: 441 REPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTF----- 495
Query: 182 DLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIREN 241
L + Q + + A + S R R +E+ER+ L+ R+
Sbjct: 496 --LHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLR--------RKE 545
Query: 242 EARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLRQ 301
EA QL + + L ++K E LR+ R + E +KE++K +E + A++ +
Sbjct: 546 EAEQLRRQKVEEDKRRRLEEVKLKREERLRK-VLQARERVEQMKEEKKKQIEQKFAQIDE 604
Query: 302 KKMKKSKEGGTEEE 315
K K +E EE+
Sbjct: 605 KTEKAKEERLAEEK 618
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 49.3 bits (116), Expect = 7e-06
Identities = 75/326 (23%), Positives = 142/326 (43%), Gaps = 55/326 (16%)
Query: 2 DRRKKPLDVTASSLVDLKAELFRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGV 61
++ K+ L +++ +LKA+L RK+E++ K K + + K K+ S+ ++ +
Sbjct: 1218 EKLKEELSASSARTQNLKADLQRKEEDYADLKE-KLTDAKKQIKQVQKEVSVMRDEDKLL 1276
Query: 62 S---NRAEKDAEQKIEE----QKTLDKARE-----KLEEKAKLYEKMTKGDFIDEEV-ED 108
N EK Q +E Q+T+ + +E K+EE + YE+ K + E++ ED
Sbjct: 1277 RIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIED 1336
Query: 109 MYLV--DFTQKIIDKRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYV 166
M + + Q +++ + +EA + A E + +E + E Q ++E +
Sbjct: 1337 MRMTLEEQEQTQVEQDQVLEAK-LEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNT 1395
Query: 167 DSLGRSRRCMRKDLPDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREAL 226
D LG+ NLQ L S + + R++W EE+ +
Sbjct: 1396 DVLGKLT---------------NLQDELQES----------EQKYNADRKKWLEEKMMLI 1430
Query: 227 KRPMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKE 286
+ E+IR E ++ +A D+E KQ +E+L Q T++ + + +E
Sbjct: 1431 TQAK---EAENIRNKEMKK-------YAEDRERFFKQQNEMEILTAQLTEKDSDLQKWRE 1480
Query: 287 KRK---AILEARLAKLRQKKMKKSKE 309
+R A LE +L L ++K E
Sbjct: 1481 ERDQLVAALEIQLKALISSNVQKDNE 1506
Score = 37.7 bits (86), Expect = 0.022
Identities = 59/259 (22%), Positives = 104/259 (40%), Gaps = 36/259 (13%)
Query: 72 KIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAH 131
K EE++T + EKL+E+ T+ D + ++ D +K+ D +K++
Sbjct: 1206 KEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQI------ 1259
Query: 132 RDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQ 191
+ QK DE+ L +I + + +D R+ + +++ L + + Q
Sbjct: 1260 KQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQ 1319
Query: 192 GRLFISPANEKTLLSEDMRKELQRQ-QWEEEEREALKRPMGPVHYEDIRENEARQLGVGY 250
N K + EDMR L+ Q Q + E+ + L+ + V E A +L +
Sbjct: 1320 YERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEV------ERLATEL-EKW 1372
Query: 251 FAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEK-----------RKAILEARL--- 296
D E +N Q E E TD K N++++ RK LE ++
Sbjct: 1373 KEKCNDLETKNNQRSNKE--HENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLI 1430
Query: 297 ------AKLRQKKMKKSKE 309
+R K+MKK E
Sbjct: 1431 TQAKEAENIRNKEMKKYAE 1449
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 48.9 bits (115), Expect = 1e-05
Identities = 62/297 (20%), Positives = 130/297 (43%), Gaps = 53/297 (17%)
Query: 21 ELFRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQKTLD 80
E R+QEE EK + K ++ +W K+ + ++KI EQ+
Sbjct: 316 EKMRRQEEMMWEK---------EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 366
Query: 81 KAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAHRDSQKAGER 140
+ EK+ E+ K E+ K +E++ + +KI ++ + M+ +K GE+
Sbjct: 367 QEEEKIREQEKRQEQEAKMWRQEEKIREQ-----EEKIREQEEMMQ-----EQEEKMGEQ 416
Query: 141 DDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQGRLFISPAN 200
EE + E E EE + + + R +R+ + E ++ ++ + +
Sbjct: 417 ---EEKMWEQE--------EEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 465
Query: 201 EKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRENEARQLGVGYFAFARDKELR 260
E+ + E K +++ +E+ E ++R E IRE E + R++E +
Sbjct: 466 EEK-MGEQEGKMCEQEAKMQEQEEKMRR-----QEEKIREQEKK---------IREQEEK 510
Query: 261 NKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLRQKKMKKSKEGGTEEENR 317
++ + EM++EQ + E + E+ + + E +++KM++ +E E+E R
Sbjct: 511 IREQE--EMMQEQEEKMWEQEEKMCEQEEKMQE------QEEKMRRQEEKMREQEVR 559
Score = 48.1 bits (113), Expect = 2e-05
Identities = 65/325 (20%), Positives = 136/325 (41%), Gaps = 37/325 (11%)
Query: 56 KQNVGVSNRAEKDAEQKIEEQKTLDKAREKLEEKAKLY----EKMTKGDFIDEEVEDMYL 111
++N + + + +K E Q + + + KLE +AKL + + D + +E++ +
Sbjct: 209 EKNAKLQEKLQLVESEKSEIQLNVKELKRKLE-RAKLLLPQQQLQAEADHLGKELQSVSA 267
Query: 112 VDFTQ----KIIDKRKEMEASGAHRDSQKAGERDD----DEENLPEGEIPPPQDPSEEWV 163
Q ++ ++ + + R +K ER++ EE + E E + W
Sbjct: 268 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMW- 326
Query: 164 DYVDSLGRSRRCMRKDLPDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQ-----W 218
+ + + R M + + E+++ + + I EK E +R++ +RQ+ W
Sbjct: 327 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 386
Query: 219 EEEEREALKRPMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQR 278
+EE+ + E ++E E + E K + E ++EQ R
Sbjct: 387 RQEEKIREQEEKIREQEEMMQEQEEKM-----------GEQEEKMWEQEEEMQEQEEKMR 435
Query: 279 TKRENIKEKRKAILEARLAKLRQKKMKKSKEGGTEEENRDGDVIGPLPPEPEAVPTPRPA 338
+ E I+E+ K I E +++K+++ +E E+E + G+ G + E EA +
Sbjct: 436 RQEEKIREQEKKIRE------QEEKIREQEEMMQEQEEKMGEQEGKM-CEQEAKMQEQEE 488
Query: 339 AQSSKVEVIVQERKDTKPGVPHIRE 363
+ E I ++ K + IRE
Sbjct: 489 KMRRQEEKIREQEKKIREQEEKIRE 513
Score = 42.7 bits (99), Expect = 7e-04
Identities = 49/248 (19%), Positives = 112/248 (45%), Gaps = 43/248 (17%)
Query: 21 ELFRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQKTLD 80
E R+QEE +QE + + + K ++ +W ++ ++ E+KI EQ+ +
Sbjct: 357 EKIREQEEKRQE----EEKIREQEKRQEQEAKMWRQEE------KIREQEEKIREQEEMM 406
Query: 81 KAREKL--EEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEM-EASGAHRDSQKA 137
+ +E+ E++ K++E+ + + E+ E M + +KI ++ K++ E R+ ++
Sbjct: 407 QEQEEKMGEQEEKMWEQEEE---MQEQEEKMRRQE--EKIREQEKKIREQEEKIREQEEM 461
Query: 138 GERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQGRLFIS 197
+ +++ EG++ + +E MR+ + E +K ++ +
Sbjct: 462 MQEQEEKMGEQEGKMCEQEAKMQE----------QEEKMRRQEEKIREQEKKIREQ---- 507
Query: 198 PANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRENEARQLGVGYFAFARDK 257
EK E+M +E + + WE+EE+ + E +R E + R++
Sbjct: 508 --EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM---------REQ 556
Query: 258 ELRNKQMK 265
E+R +Q +
Sbjct: 557 EVRLRQQE 564
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 47.4 bits (111), Expect = 3e-05
Identities = 66/326 (20%), Positives = 126/326 (38%), Gaps = 31/326 (9%)
Query: 64 RAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRK 123
R EKD +K D+ RE+ ++ K E+ T D E + +K +++K
Sbjct: 82 RREKDRHRK------RDRHRERQRDREKERERQT-----DRERDRQ-----REKERNRQK 125
Query: 124 EMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDL 183
E E R++++ GER D + + E +D +E D +R ++
Sbjct: 126 ERE-----RETEREGERGRDRQTDGQRERERQRDAEKERERQTDR--ERQRQTERNRQKE 178
Query: 184 LEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRENEA 243
E +KN Q R EK +ED E R++ E E E E R+ +
Sbjct: 179 REREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKT 238
Query: 244 RQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLRQKK 303
+ R+K+ ++ E R++ ++ R+ +++R+ E + + RQ++
Sbjct: 239 ER--------EREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRR 290
Query: 304 MKKSKEGGTEEENRDGDVIGPLPPEPEAVPTPRPAAQSSKVEVIVQERKDTKPGVPHIRE 363
++ +E + E + R + + E K+ + E
Sbjct: 291 TERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTE 350
Query: 364 WDRGKEFSFGYWSKRQSDLRAERDPE 389
DR + G +RQ++ ER+ E
Sbjct: 351 MDRERNRQTGREGRRQAERERERERE 376
Score = 40.8 bits (94), Expect = 0.003
Identities = 73/393 (18%), Positives = 150/393 (38%), Gaps = 46/393 (11%)
Query: 66 EKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEM 125
EK+ E++ + ++ + +E+ +K + E +G+ + D Q+ +K +E
Sbjct: 102 EKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERER 161
Query: 126 EASG-----AHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDL 180
+ R+ QK ER+ + + E E ++ E D GR R R+
Sbjct: 162 QTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTE--DRHSERGRERERERETE 219
Query: 181 PDL-------LEMDKNLQGRLFISPANEKTLLSE-DMRKELQRQQWEEEEREALKRPMGP 232
+ E D+ + E+ SE + ++ +R++ + +R+ +R
Sbjct: 220 TETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKER 279
Query: 233 VHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEK---RK 289
D + + RD+E K+ + E RE+ +++ +RE +E+ R+
Sbjct: 280 ERQTDRKRQRRTE---------RDRETERKRERQRERERERERNRKRERERERERERERQ 330
Query: 290 AILEARLAKLRQKKMKKSKEGGTE---------------EENRDGDVIGPLPPEPEAVPT 334
E K R++K K+ E E E R+ + E E
Sbjct: 331 RETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERER 390
Query: 335 PRPAAQSSKVEVIVQERKDTKPGVPHIREWDRGKEFSFGYWSKRQSDLRAERDPEFAPPS 394
R + + E ++ +D + RE ++ +E G R+ + + R+ + +
Sbjct: 391 DRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQT 450
Query: 395 DYFVGQKRTG----FSSSQAWSRPGPAQSDPGQ 423
D G++R + +R G QSDP +
Sbjct: 451 DRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNR 483
Score = 35.0 bits (79), Expect = 0.15
Identities = 52/291 (17%), Positives = 112/291 (38%), Gaps = 57/291 (19%)
Query: 25 KQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQKTLDKARE 84
++ E + E+ + + + T ++ +++ E+D E++ E + D+ R
Sbjct: 216 RETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRR 275
Query: 85 KLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAHRDSQKAGERDDDE 144
+ E + + K + D E E KR+ R+ + ER+ +
Sbjct: 276 QKERERQTDRKRQRRTERDRETE------------RKRERQRERERERERNRKRERERER 323
Query: 145 ENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQGRLFISPANEKTL 204
E E + +D +E R R+ R+ EMD+ N +T
Sbjct: 324 ERERERQRETERDREKE---------RERKRKRQ-----TEMDRE---------RNRQT- 359
Query: 205 LSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQM 264
+ R++ +R++ E ER+ + RE E R+ RD++ + ++
Sbjct: 360 -GREGRRQAERERERERERDR----------QSAREREERERD-------RDRDRQKERE 401
Query: 265 KTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLRQKKMKKSKEGGTEEE 315
+ E R+ + +RE K++ E + R+++ +K +E E +
Sbjct: 402 RQTEKDRDGQRETEKQREREKDRES---ERGRERGREREKQKGRERDRERQ 449
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 46.6 bits (109), Expect = 5e-05
Identities = 72/320 (22%), Positives = 129/320 (40%), Gaps = 50/320 (15%)
Query: 26 QEEFKQEKLLKDSGVFGKPKTTN------KKPSIWSK------QNVGVSNRAEKDAEQKI 73
+E+ KQ K + + KT + KP ++SK + V R + A++K
Sbjct: 443 EEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKE 502
Query: 74 EEQKTLDKAREKLEEKAKLYEKMTKG--------DFIDEEVEDMYLVD----FTQKIIDK 121
E REKLEEK K + TK +D E ++ ++++ +
Sbjct: 503 ERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKE 562
Query: 122 RKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLP 181
RK +E A +K R+ +E + + + EE D ++L S C ++ +
Sbjct: 563 RKVLEKKVALSKKRKKDSRNVEENSKKKQQY-------EE--DSKETLKTSEHCEKEKIS 613
Query: 182 DLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIREN 241
E+ K++ + P+ LSE + + + + ERE +R PV E ++E
Sbjct: 614 SSKEL-KHVHAK--SEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIMEGVQEE 670
Query: 242 EARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEA-RLAKLR 300
D +Q++ E+ E+ Q++ +N K +K E L L
Sbjct: 671 -------------TDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLL 717
Query: 301 QKKMKKSKEGGTEEENRDGD 320
+K++K SKE E+ D
Sbjct: 718 KKEVKSSKEKPEREKTPSED 737
Score = 35.4 bits (80), Expect = 0.11
Identities = 58/308 (18%), Positives = 121/308 (39%), Gaps = 26/308 (8%)
Query: 67 KDAEQKIEEQK--TLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKR-- 122
KD +Q+ EQK + DK +K + K K K + +++ + + TQK+ D++
Sbjct: 305 KDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQA 364
Query: 123 KEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPD 182
KE E S+K + E E D V S+ S D
Sbjct: 365 KEKEVESLKLPSEKNSNKAKTVEGTKEDFSLIDSDVDGLTDITVSSVHTS---------D 415
Query: 183 LLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRENE 242
L +++ + + S + E+ ++ D ++ ++ + + + ++ + V + + +
Sbjct: 416 LSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHK-- 473
Query: 243 ARQLGVGYFAFARDK-ELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLRQ 301
L Y++ + D+ + ++ + E+ ++ RE ++EKRK +
Sbjct: 474 -PYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQ---------KA 523
Query: 302 KKMKKSKEGGTEEENRDGDVIGPLPPEPEAVPTPRPAAQSSKVEVIVQERKDTKPGVPHI 361
+K K SK G + D + EP+A + +E V K K ++
Sbjct: 524 EKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNV 583
Query: 362 REWDRGKE 369
E + K+
Sbjct: 584 EENSKKKQ 591
>gi|219803769 trichoplein [Homo sapiens]
Length = 498
Score = 46.2 bits (108), Expect = 6e-05
Identities = 57/258 (22%), Positives = 116/258 (44%), Gaps = 36/258 (13%)
Query: 66 EKDAEQKIEEQKTLDKAR---EKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKR 122
E +A + +EQ+ L K R E+LEE+ K E + + + Y +++ +
Sbjct: 231 EVEATKLKKEQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSRRTQQIQ 290
Query: 123 KEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPD 182
+E+EA R Q E++D+ + L L R + M D
Sbjct: 291 EELEAD--RRILQALLEKEDESQRL--------------------HLARREQVMA----D 324
Query: 183 LLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEERE-ALKRPMGPVHYEDIREN 241
+ M + ++ +L + A E L + + +E ++ WE+ E E A +R ++
Sbjct: 325 VAWMKQAIEEQLQLERAREAEL--QMLLREEAKEMWEKREAEWARERSARDRLMSEVLTG 382
Query: 242 EARQLG--VGYFAFARDKELRNKQ--MKTLEMLREQTTDQRTKRENIKEKRKAILEARLA 297
+Q+ + A+++ L++++ ++ LE +RE ++ + E +K RK LEA++A
Sbjct: 383 RQQQIQEKIEQNRRAQEESLKHREQLIRNLEEVRELARREKEESEKLKSARKQELEAQVA 442
Query: 298 KLRQKKMKKSKEGGTEEE 315
+ R + + ++ EEE
Sbjct: 443 ERRLQAWEADQQEEEEEE 460
>gi|14150056 trichoplein [Homo sapiens]
Length = 498
Score = 46.2 bits (108), Expect = 6e-05
Identities = 57/258 (22%), Positives = 116/258 (44%), Gaps = 36/258 (13%)
Query: 66 EKDAEQKIEEQKTLDKAR---EKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKR 122
E +A + +EQ+ L K R E+LEE+ K E + + + Y +++ +
Sbjct: 231 EVEATKLKKEQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSRRTQQIQ 290
Query: 123 KEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPD 182
+E+EA R Q E++D+ + L L R + M D
Sbjct: 291 EELEAD--RRILQALLEKEDESQRL--------------------HLARREQVMA----D 324
Query: 183 LLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEERE-ALKRPMGPVHYEDIREN 241
+ M + ++ +L + A E L + + +E ++ WE+ E E A +R ++
Sbjct: 325 VAWMKQAIEEQLQLERAREAEL--QMLLREEAKEMWEKREAEWARERSARDRLMSEVLTG 382
Query: 242 EARQLG--VGYFAFARDKELRNKQ--MKTLEMLREQTTDQRTKRENIKEKRKAILEARLA 297
+Q+ + A+++ L++++ ++ LE +RE ++ + E +K RK LEA++A
Sbjct: 383 RQQQIQEKIEQNRRAQEESLKHREQLIRNLEEVRELARREKEESEKLKSARKQELEAQVA 442
Query: 298 KLRQKKMKKSKEGGTEEE 315
+ R + + ++ EEE
Sbjct: 443 ERRLQAWEADQQEEEEEE 460
>gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar)
[Homo sapiens]
Length = 731
Score = 45.4 bits (106), Expect = 1e-04
Identities = 48/271 (17%), Positives = 113/271 (41%), Gaps = 26/271 (9%)
Query: 33 KLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQKTLDKAREKLEEKAKL 92
+LL S + P+ P + G + E +++ EE D E + ++
Sbjct: 472 QLLPSSSLEVVPEAAQNNPGEEVTETAGEGS--ESIIKEETEENSHCDANTEMQQILTRV 529
Query: 93 YEKMTKGDFIDE-EVEDMYLVDFTQKIIDKRKEMEASGAHRDSQKAGERDDDEENLPEGE 151
+ K + + + +D+ V+ + D +E+E+ + ++ +RDD EE+ E E
Sbjct: 530 RQNFGKINVVPQFSGDDLVPVE----VSDLEEELESFSDEEEEEQEQQRDDAEESSSEPE 585
Query: 152 IPPPQDPSEEWVDYVD-SLGRSRRCMRKDLP---DLLEMDKNLQGRLFISPANEKTLLSE 207
+ ++ + +D + + ++ + K + + K L ++F P ++ L E
Sbjct: 586 EENVGNDTKAVIKALDEKIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEE 645
Query: 208 DM----------RKELQRQQWEEEEREALKRPMGPVHYEDIRENEARQLGVGYFAFARDK 257
D+ +++ QR++ +E +A + +R+ +++GV Y+ K
Sbjct: 646 DVDDRAPSKKGKKRKAQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVK 705
Query: 258 ELRNKQMKTLEMLREQTTDQRTKRENIKEKR 288
+ KT + Q+ KR+ ++K+
Sbjct: 706 NRNRNKKKT-----NDSEGQKHKRKKFRQKQ 731
>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
sapiens]
Length = 1352
Score = 45.1 bits (105), Expect = 1e-04
Identities = 57/295 (19%), Positives = 120/295 (40%), Gaps = 14/295 (4%)
Query: 76 QKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAHRDSQ 135
Q ++ K + E++ K FI ++ + + + ID+ K+ + +
Sbjct: 263 QSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYE 322
Query: 136 KAGERDDDEENLPEGE------IPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKN 189
+G +++EEN GE +P +++ + +R+ + + +
Sbjct: 323 YSGSEEEEEEN-DSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENE 381
Query: 190 LQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYED--IRENEARQLG 247
R ++ ++ ++ R+ L+ QQ E+E + HYE+ RE E R+
Sbjct: 382 EHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAE 441
Query: 248 VGYFAFARDKELRNKQMKTL--EMLREQTTDQRTKRENIKEKRKAILEARLAKLRQKKMK 305
R E +Q++ L ++L EQ KR+ ++E+R+A E +L+Q++
Sbjct: 442 HEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQA--ERLQRQLKQERDY 499
Query: 306 KSKEGGTEEENRDGDVIGPLPPEPEAVPTPRPAAQSSKVEVIVQERKDTKPGVPH 360
+E R + PL E + A + +VE + + + P +PH
Sbjct: 500 LVSLQHQRQEQRPVEK-KPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSPAMPH 553
>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
sapiens]
Length = 1360
Score = 45.1 bits (105), Expect = 1e-04
Identities = 57/295 (19%), Positives = 120/295 (40%), Gaps = 14/295 (4%)
Query: 76 QKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAHRDSQ 135
Q ++ K + E++ K FI ++ + + + ID+ K+ + +
Sbjct: 263 QSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYE 322
Query: 136 KAGERDDDEENLPEGE------IPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKN 189
+G +++EEN GE +P +++ + +R+ + + +
Sbjct: 323 YSGSEEEEEEN-DSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENE 381
Query: 190 LQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYED--IRENEARQLG 247
R ++ ++ ++ R+ L+ QQ E+E + HYE+ RE E R+
Sbjct: 382 EHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAE 441
Query: 248 VGYFAFARDKELRNKQMKTL--EMLREQTTDQRTKRENIKEKRKAILEARLAKLRQKKMK 305
R E +Q++ L ++L EQ KR+ ++E+R+A E +L+Q++
Sbjct: 442 HEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQA--ERLQRQLKQERDY 499
Query: 306 KSKEGGTEEENRDGDVIGPLPPEPEAVPTPRPAAQSSKVEVIVQERKDTKPGVPH 360
+E R + PL E + A + +VE + + + P +PH
Sbjct: 500 LVSLQHQRQEQRPVEK-KPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSPAMPH 553
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 45.1 bits (105), Expect = 1e-04
Identities = 66/286 (23%), Positives = 116/286 (40%), Gaps = 47/286 (16%)
Query: 64 RAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGD-------FIDEEVEDMYLVDFTQ 116
+ EK +++ E+ K DK++EK + K K +K T + F+ EE D Y +
Sbjct: 535 KKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLKEEEADPYKFKIKE 594
Query: 117 -KIIDKRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRC 175
+ +D + +++ ++ +K ++ D E +D + + V GR +
Sbjct: 595 FEDVDPKVKLKDGLVRKEKEKHKDKKKDREK-------GKKDKDKREKEKVKDKGREDK- 646
Query: 176 MRKDLPDLLEMDKNLQGRLFISPANEKTL--LSEDMRKELQRQQWEEEEREALKRPMGPV 233
M+ P L+ K L LF SPA + + + L + +EE+E+
Sbjct: 647 MKAPAPPLVLPPKELALPLF-SPATASRVPAMLPSLLPVLPEKLFEEKEK---------- 695
Query: 234 HYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRK---- 289
++E E ++ K+ + K+ + E RE+ +R KRE KEK K
Sbjct: 696 ----VKEKEKKK------DKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKI 745
Query: 290 AILEARLAKLRQKKMKKSKEGGTEEENRDGDVIGPLPPEPEAVPTP 335
+ LA + G +D VI + P PEA P P
Sbjct: 746 KVEPVALAPSPVIPRLTLRVGA----GQDKIVISKVVPAPEAKPAP 787
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 45.1 bits (105), Expect = 1e-04
Identities = 51/224 (22%), Positives = 103/224 (45%), Gaps = 20/224 (8%)
Query: 8 LDVTASSLVDLKAELFRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEK 67
L + L + K +L ++ E K K+ + + K K K+ I + VSN AE+
Sbjct: 1572 LKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAER 1631
Query: 68 DAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEA 127
Q ++ R +EK +LY K+ + +E E + ++ +++ KE
Sbjct: 1632 -------IQHVVEAVR---QEKQELYGKLRSTEANKKETEKQ--LQEAEQEMEEMKEKMR 1679
Query: 128 SGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMD 187
A QK E +++ + L E+ P D ++E +++L S M+++L + ++M+
Sbjct: 1680 KFAKSKQQKILELEEENDRL-RAEVHPAGDTAKE---CMETLLSSNASMKEEL-ERVKME 1734
Query: 188 KNLQGRLFISPANEKTLLSE---DMRKELQRQQWEEEEREALKR 228
+ F S +EK LSE D++ +++ ++ EA ++
Sbjct: 1735 YETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEK 1778
Score = 32.7 bits (73), Expect = 0.72
Identities = 79/433 (18%), Positives = 161/433 (37%), Gaps = 82/433 (18%)
Query: 57 QNVGVSNRAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQ 116
+ +G +RA++ ++K+ Q L +E L+E L E+++ E + T+
Sbjct: 1469 EEIGEESRAKQQIQRKL--QAALISRKEALKENKSLQEELSLARGTIERL--------TK 1518
Query: 117 KIIDKRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVD-------SL 169
+ D ++ A +D+ G + Q+ ++ + +D SL
Sbjct: 1519 SLADVESQVSAQNKEKDTVL-------------GRLALLQEERDKLITEMDRSLLENQSL 1565
Query: 170 GRSRRCMRKDLPDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKR- 228
S ++ L L E + L K + S K + +W+E+ +E K
Sbjct: 1566 SSSCESLKLALEGLTEDKEKLV----------KEIESLKSSKIAESTEWQEKHKELQKEY 1615
Query: 229 PMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKR 288
+ YE++ NEA ++ A ++K+ E+ + + + K+E K+ +
Sbjct: 1616 EILLQSYENV-SNEAERIQHVVEAVRQEKQ---------ELYGKLRSTEANKKETEKQLQ 1665
Query: 289 KAILEARLAKLRQKKMKKSKEGGTEEENRDGDVIGPLPPEPEAVPTPRPAAQSSK--VEV 346
+A E K + +K KSK+ E + D + PA ++K +E
Sbjct: 1666 EAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLR---------AEVHPAGDTAKECMET 1716
Query: 347 IVQERKDTKPGVPHIREWDRGKEFSFGYWSKRQSDLRAERDPEFAPPSDY---------- 396
++ K + ++ + SK+ L +E+D D
Sbjct: 1717 LLSSNASMKEELERVK-------MEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSK 1769
Query: 397 FVGQKRTGFSSSQAWSRPGPAQSDPGQCPDQ---SHGPSPEHTSPTPAPDNPPQAPTVTF 453
+ T +Q QS PG+ +Q S P + P+ + A + F
Sbjct: 1770 QANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDF 1829
Query: 454 KTLDDMISYYKQV 466
+ D++ +Y +Q+
Sbjct: 1830 SSHDEINNYLQQI 1842
Score = 30.8 bits (68), Expect = 2.7
Identities = 54/308 (17%), Positives = 130/308 (42%), Gaps = 29/308 (9%)
Query: 21 ELFRKQEEFKQEKLLKDSGV-----FGKPKTTNKKPSIWS-KQNVGVSNRAEKDAEQKI- 73
+L +K E ++E+ D+ + K K T+ I K G E +E+++
Sbjct: 74 QLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQSEEQLS 133
Query: 74 -------EEQKTLDKAREKLEEKAKLYE----KMTKGDFIDEEVEDMYLVDFT---QKII 119
EE+ ++K + KL+EK +L ++T+ + +F Q++
Sbjct: 134 KHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQ 193
Query: 120 DKRK---EMEASGAHRDSQKAGERDDDEENLP-EGEIPPPQDPSEEWVDYVDSLGRSRRC 175
+K + ++A + +++A ++ E++ E ++ +D + V D ++
Sbjct: 194 EKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQK 253
Query: 176 MRKDLPDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWE--EEEREALKRPMGPV 233
+R L E +++L GR + ++ L + + R ++ QQ + E E L+ +
Sbjct: 254 LRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETE 313
Query: 234 HYED--IRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAI 291
E + E ++ +F +E + ++ E + + ++ +++K KA
Sbjct: 314 REESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAE 373
Query: 292 LEARLAKL 299
+E + + +
Sbjct: 374 MEEKTSHI 381
Score = 30.4 bits (67), Expect = 3.6
Identities = 36/182 (19%), Positives = 87/182 (47%), Gaps = 23/182 (12%)
Query: 56 KQNVGVSNRAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFT 115
K+ + + +RAE+ ++++EE + ++ Y++M+ I +E E + D
Sbjct: 932 KEQLNLLSRAEEAKKEQVEEDNEVSSGLKQN------YDEMSPAGQISKE-ELQHEFDLL 984
Query: 116 QKIIDKRK-EMEASGAHRDS--QKAGERDDDEENLPEG---EIPPPQDPSEEWVDYVDSL 169
+K ++RK +++A+ +R Q+ +++ NL + EIP + E + ++
Sbjct: 985 KKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENK 1044
Query: 170 GRSRRCMRKDLPDLLEMDKNLQGRLFISPA-NEKTLLSEDMRKELQRQQWEEEEREALKR 228
S +C+ ++ +++ +EK + + +RK+L+ + EE+ +AL +
Sbjct: 1045 EYSEKCVTSKCQEI---------EIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVK 1095
Query: 229 PM 230
M
Sbjct: 1096 QM 1097
>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
Length = 495
Score = 44.7 bits (104), Expect = 2e-04
Identities = 65/292 (22%), Positives = 126/292 (43%), Gaps = 61/292 (20%)
Query: 67 KDAEQKIEEQKTLDKAREKLEEK-----AKLYEKMTKGDFIDEEVEDMYL----VDFTQK 117
++A QK EE K L + + K EEK AKL + K + + ++V + + ++ K
Sbjct: 70 EEAIQKAEENKRLKELQLKQEEKLAMELAKLKHESLKDEKMRQQVRENSIELRELEKKLK 129
Query: 118 IIDKRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMR 177
KE A A +D+ K + D E + + + + +E D +++
Sbjct: 130 AAYMNKERAAQIAEKDAIKYEQMKRDAE-IAKTMMEEHKRIIKEENAAEDKRNKAKAQYY 188
Query: 178 KDLPDLLEMDKNLQGRLFISPANEKTLLSEDMRK-----ELQRQQ--------------- 217
DL LE + + + EK ++ E +RK +L++QQ
Sbjct: 189 LDLEKQLEEQEKKKQEAYEQLLKEKLMIDEIVRKIYEEDQLEKQQKLEKMNAMRRYIEEF 248
Query: 218 ------WEEEEREALKRP---------MGPVHYED----IRENEARQLGVGYFAFARDKE 258
W +++RE ++ M ED ++ENE ++L +
Sbjct: 249 QKEQALWRKKKREEMEEENRKIIEFANMQQQREEDRMAKVQENEEKRL-----------Q 297
Query: 259 LRNKQMKTLE-MLREQTTDQRTKRENIKEKRKAILEARLAKLRQKKMKKSKE 309
L+N + LE MLR++ ++ ++E +E++ I +++L + +KK++K KE
Sbjct: 298 LQNALTQKLEEMLRQREDLEQVRQELYQEEQAEIYKSKLKEEAEKKLRKQKE 349
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 44.3 bits (103), Expect = 2e-04
Identities = 60/267 (22%), Positives = 118/267 (44%), Gaps = 25/267 (9%)
Query: 46 TTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTK-GDFIDE 104
T N + S K+ ++ E E K QK ++ ++ EEKA Y+K+ K + + +
Sbjct: 1368 TLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ 1427
Query: 105 EVEDM--------YLVDFTQKIIDKRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQ 156
E++D+ LV +K K ++ A + S+ A ERD E E E
Sbjct: 1428 ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALS 1487
Query: 157 --DPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQGRLFISPANEKTLLS--EDMRKE 212
EE ++ + L R+ + ++ ++ DL+ ++ + +++ L + E+M+ +
Sbjct: 1488 LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQ 1547
Query: 213 LQRQQWEEEEREALKRPMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLRE 272
L+ + E + E K + V+ + ++ R L ARD++ K+ + L E
Sbjct: 1548 LEELEDELQATEDAKLRL-EVNMQALKGQFERDLQ------ARDEQNEEKRRQLQRQLHE 1600
Query: 273 QTTDQRTKRENIKEKRKAILEARLAKL 299
T+ +R K++A+ A KL
Sbjct: 1601 YETELEDER-----KQRALAAAAKKKL 1622
Score = 33.5 bits (75), Expect = 0.42
Identities = 55/271 (20%), Positives = 112/271 (41%), Gaps = 42/271 (15%)
Query: 64 RAEKDAEQKIEEQKTLDKAREKLEEKAK------LYEKMTKGDFIDEEVEDMYLVDFTQK 117
R E++ E++ + Q+ L + +LE++ K +K +GD D E++ + ++
Sbjct: 1583 RDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 1642
Query: 118 II-----------DKRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYV 166
I D ++E+E + A RD A ++++++ + + +
Sbjct: 1643 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK---------AKSLEADLMQLQ 1693
Query: 167 DSLGRSRRCMRKDLPDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREAL 226
+ L + R ++ + E+ + L L + L E R E + Q EEE L
Sbjct: 1694 EDLAAAERARKQADLEKEELAEELASSL----SGRNALQDEKRRLEARIAQLEEE----L 1745
Query: 227 KRPMGPVHYEDIRENEARQLGVGYF-AFARDKELRNKQMKTLEMLREQTTDQRTKREN-- 283
+ G + R +A Q A ++ K + L Q + R+K
Sbjct: 1746 EEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEME 1805
Query: 284 --IKEKRK---AILEARLAKLRQKKMKKSKE 309
+K K K A LEA++A+L ++ ++++E
Sbjct: 1806 GAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1836
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 44.3 bits (103), Expect = 2e-04
Identities = 60/267 (22%), Positives = 118/267 (44%), Gaps = 25/267 (9%)
Query: 46 TTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTK-GDFIDE 104
T N + S K+ ++ E E K QK ++ ++ EEKA Y+K+ K + + +
Sbjct: 1375 TLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ 1434
Query: 105 EVEDM--------YLVDFTQKIIDKRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQ 156
E++D+ LV +K K ++ A + S+ A ERD E E E
Sbjct: 1435 ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALS 1494
Query: 157 --DPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQGRLFISPANEKTLLS--EDMRKE 212
EE ++ + L R+ + ++ ++ DL+ ++ + +++ L + E+M+ +
Sbjct: 1495 LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQ 1554
Query: 213 LQRQQWEEEEREALKRPMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLRE 272
L+ + E + E K + V+ + ++ R L ARD++ K+ + L E
Sbjct: 1555 LEELEDELQATEDAKLRL-EVNMQALKGQFERDLQ------ARDEQNEEKRRQLQRQLHE 1607
Query: 273 QTTDQRTKRENIKEKRKAILEARLAKL 299
T+ +R K++A+ A KL
Sbjct: 1608 YETELEDER-----KQRALAAAAKKKL 1629
Score = 33.5 bits (75), Expect = 0.42
Identities = 55/271 (20%), Positives = 112/271 (41%), Gaps = 42/271 (15%)
Query: 64 RAEKDAEQKIEEQKTLDKAREKLEEKAK------LYEKMTKGDFIDEEVEDMYLVDFTQK 117
R E++ E++ + Q+ L + +LE++ K +K +GD D E++ + ++
Sbjct: 1590 RDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 1649
Query: 118 II-----------DKRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYV 166
I D ++E+E + A RD A ++++++ + + +
Sbjct: 1650 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK---------AKSLEADLMQLQ 1700
Query: 167 DSLGRSRRCMRKDLPDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREAL 226
+ L + R ++ + E+ + L L + L E R E + Q EEE L
Sbjct: 1701 EDLAAAERARKQADLEKEELAEELASSL----SGRNALQDEKRRLEARIAQLEEE----L 1752
Query: 227 KRPMGPVHYEDIRENEARQLGVGYF-AFARDKELRNKQMKTLEMLREQTTDQRTKREN-- 283
+ G + R +A Q A ++ K + L Q + R+K
Sbjct: 1753 EEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEME 1812
Query: 284 --IKEKRK---AILEARLAKLRQKKMKKSKE 309
+K K K A LEA++A+L ++ ++++E
Sbjct: 1813 GAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1843
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 44.3 bits (103), Expect = 2e-04
Identities = 60/267 (22%), Positives = 118/267 (44%), Gaps = 25/267 (9%)
Query: 46 TTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTK-GDFIDE 104
T N + S K+ ++ E E K QK ++ ++ EEKA Y+K+ K + + +
Sbjct: 1375 TLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ 1434
Query: 105 EVEDM--------YLVDFTQKIIDKRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQ 156
E++D+ LV +K K ++ A + S+ A ERD E E E
Sbjct: 1435 ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALS 1494
Query: 157 --DPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQGRLFISPANEKTLLS--EDMRKE 212
EE ++ + L R+ + ++ ++ DL+ ++ + +++ L + E+M+ +
Sbjct: 1495 LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQ 1554
Query: 213 LQRQQWEEEEREALKRPMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLRE 272
L+ + E + E K + V+ + ++ R L ARD++ K+ + L E
Sbjct: 1555 LEELEDELQATEDAKLRL-EVNMQALKGQFERDLQ------ARDEQNEEKRRQLQRQLHE 1607
Query: 273 QTTDQRTKRENIKEKRKAILEARLAKL 299
T+ +R K++A+ A KL
Sbjct: 1608 YETELEDER-----KQRALAAAAKKKL 1629
Score = 33.5 bits (75), Expect = 0.42
Identities = 55/271 (20%), Positives = 112/271 (41%), Gaps = 42/271 (15%)
Query: 64 RAEKDAEQKIEEQKTLDKAREKLEEKAK------LYEKMTKGDFIDEEVEDMYLVDFTQK 117
R E++ E++ + Q+ L + +LE++ K +K +GD D E++ + ++
Sbjct: 1590 RDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 1649
Query: 118 II-----------DKRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYV 166
I D ++E+E + A RD A ++++++ + + +
Sbjct: 1650 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK---------AKSLEADLMQLQ 1700
Query: 167 DSLGRSRRCMRKDLPDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREAL 226
+ L + R ++ + E+ + L L + L E R E + Q EEE L
Sbjct: 1701 EDLAAAERARKQADLEKEELAEELASSL----SGRNALQDEKRRLEARIAQLEEE----L 1752
Query: 227 KRPMGPVHYEDIRENEARQLGVGYF-AFARDKELRNKQMKTLEMLREQTTDQRTKREN-- 283
+ G + R +A Q A ++ K + L Q + R+K
Sbjct: 1753 EEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEME 1812
Query: 284 --IKEKRK---AILEARLAKLRQKKMKKSKE 309
+K K K A LEA++A+L ++ ++++E
Sbjct: 1813 GAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1843
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.130 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,438,737
Number of Sequences: 37866
Number of extensions: 1229989
Number of successful extensions: 11757
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 108
Number of HSP's successfully gapped in prelim test: 702
Number of HSP's that attempted gapping in prelim test: 9088
Number of HSP's gapped (non-prelim): 2785
length of query: 467
length of database: 18,247,518
effective HSP length: 106
effective length of query: 361
effective length of database: 14,233,722
effective search space: 5138373642
effective search space used: 5138373642
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.