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Search of human proteins with 4557761
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557761 mutS homolog 2 [Homo sapiens]
(934 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557761 mutS homolog 2 [Homo sapiens] 1830 0.0
gi|68303635 mutS homolog 3 [Homo sapiens] 243 8e-64
gi|4504191 mutS homolog 6 [Homo sapiens] 233 5e-61
gi|36949366 mutS homolog 4 [Homo sapiens] 207 3e-53
gi|4505253 mutS homolog 5 isoform c [Homo sapiens] 150 7e-36
gi|26638662 mutS homolog 5 isoform a [Homo sapiens] 150 7e-36
gi|26638666 mutS homolog 5 isoform c [Homo sapiens] 150 7e-36
gi|26638664 mutS homolog 5 isoform b [Homo sapiens] 145 1e-34
gi|224451082 cytospin A [Homo sapiens] 40 0.013
gi|224451080 cytospin A [Homo sapiens] 40 0.013
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 39 0.029
gi|197304777 TBC1 domain family, member 5 isoform a [Homo sapiens] 35 0.43
gi|197304775 TBC1 domain family, member 5 isoform b [Homo sapiens] 35 0.43
gi|7661998 TBC1 domain family, member 5 isoform b [Homo sapiens] 35 0.43
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 35 0.43
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 33 0.95
gi|42794779 myosin 18A isoform b [Homo sapiens] 33 0.95
gi|28416946 myosin 18A isoform a [Homo sapiens] 33 0.95
gi|24308171 zinc finger protein 280C [Homo sapiens] 33 0.95
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 33 1.2
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 33 1.2
gi|151101140 coiled-coil domain containing 2 isoform a [Homo sap... 33 1.2
gi|151105223 coiled-coil domain containing 2 isoform a [Homo sap... 33 1.2
gi|151105229 coiled-coil domain containing 2 isoform a [Homo sap... 33 1.2
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 33 1.2
gi|34850061 superiorcervical ganglia, neural specific 10 [Homo s... 33 1.6
gi|4758648 kinesin family member 5B [Homo sapiens] 32 2.1
gi|50083279 centrosome protein 4 [Homo sapiens] 32 2.1
gi|225690497 tight junction associated protein 1 isoform b [Homo... 32 2.8
gi|225690495 tight junction associated protein 1 isoform b [Homo... 32 2.8
>gi|4557761 mutS homolog 2 [Homo sapiens]
Length = 934
Score = 1830 bits (4739), Expect = 0.0
Identities = 934/934 (100%), Positives = 934/934 (100%)
Query: 1 MAVQPKETLQLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKT 60
MAVQPKETLQLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKT
Sbjct: 1 MAVQPKETLQLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKT 60
Query: 61 QGVIKYMGPAGAKNLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKENDWYLA 120
QGVIKYMGPAGAKNLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKENDWYLA
Sbjct: 61 QGVIKYMGPAGAKNLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKENDWYLA 120
Query: 121 YKASPGNLSQFEDILFGNNDMSASIGVVGVKMSAVDGQRQVGVGYVDSIQRKLGLCEFPD 180
YKASPGNLSQFEDILFGNNDMSASIGVVGVKMSAVDGQRQVGVGYVDSIQRKLGLCEFPD
Sbjct: 121 YKASPGNLSQFEDILFGNNDMSASIGVVGVKMSAVDGQRQVGVGYVDSIQRKLGLCEFPD 180
Query: 181 NDQFSNLEALLIQIGPKECVLPGGETAGDMGKLRQIIQRGGILITERKKADFSTKDIYQD 240
NDQFSNLEALLIQIGPKECVLPGGETAGDMGKLRQIIQRGGILITERKKADFSTKDIYQD
Sbjct: 181 NDQFSNLEALLIQIGPKECVLPGGETAGDMGKLRQIIQRGGILITERKKADFSTKDIYQD 240
Query: 241 LNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYM 300
LNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYM
Sbjct: 241 LNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYM 300
Query: 301 KLDIAAVRALNLFQGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERL 360
KLDIAAVRALNLFQGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERL
Sbjct: 301 KLDIAAVRALNLFQGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERL 360
Query: 361 NLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQA 420
NLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQA
Sbjct: 361 NLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQA 420
Query: 421 LEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSE 480
LEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSE
Sbjct: 421 LEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSE 480
Query: 481 LREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFS 540
LREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFS
Sbjct: 481 LREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFS 540
Query: 541 TVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLA 600
TVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLA
Sbjct: 541 TVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLA 600
Query: 601 QLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKD 660
QLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKD
Sbjct: 601 QLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKD 660
Query: 661 KQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLK 720
KQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLK
Sbjct: 661 KQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLK 720
Query: 721 GVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMF 780
GVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMF
Sbjct: 721 GVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMF 780
Query: 781 ATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHV 840
ATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHV
Sbjct: 781 ATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHV 840
Query: 841 IECAKQKALELEEFQYIGESQGYDIMEPAAKKCYLEREQGEKIIQEFLSKVKQMPFTEMS 900
IECAKQKALELEEFQYIGESQGYDIMEPAAKKCYLEREQGEKIIQEFLSKVKQMPFTEMS
Sbjct: 841 IECAKQKALELEEFQYIGESQGYDIMEPAAKKCYLEREQGEKIIQEFLSKVKQMPFTEMS 900
Query: 901 EENITIKLKQLKAEVIAKNNSFVNEIISRIKVTT 934
EENITIKLKQLKAEVIAKNNSFVNEIISRIKVTT
Sbjct: 901 EENITIKLKQLKAEVIAKNNSFVNEIISRIKVTT 934
>gi|68303635 mutS homolog 3 [Homo sapiens]
Length = 1137
Score = 243 bits (619), Expect = 8e-64
Identities = 201/736 (27%), Positives = 347/736 (47%), Gaps = 73/736 (9%)
Query: 161 VGVGYVDSIQRKLGLCEFPDNDQFSNLEALLIQIGPKECVLPGG---ETAGDMGKLRQI- 216
+G+ V ++ F D+ S LE + + P E +LP +T + + +
Sbjct: 388 IGIVGVQPATGEVVFDSFQDSASRSELETRMSSLQPVELLLPSALSEQTEALIHRATSVS 447
Query: 217 IQRGGILITERKKADFSTKDIYQDLNRLLKGK----KGEQMNSAVLPEMENQVAVSSLSA 272
+Q I + F +Q + KG Q+ S ++ +E V + SL+A
Sbjct: 448 VQDDRIRVERMDNIYFEYSHAFQAVTEFYAKDTVDIKGSQIISGIV-NLEKPV-ICSLAA 505
Query: 273 VIKFLE------LLSDDSNFGQFELTTFDFSQYMKLDIAAVRALNLFQGSVEDTTGSQSL 326
+IK+L+ +LS NF Q ++M ++ +R L + Q + T SL
Sbjct: 506 IIKYLKEFNLEKMLSKPENFKQLSSKM----EFMTINGTTLRNLEILQNQTDMKTKG-SL 560
Query: 327 AALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPD 386
+L+ KT G+R + +W+ QPL+ I RL+ V + E+ LR+ PD
Sbjct: 561 LWVLDHTKTSFGRRKLKKWVTQPLLKLREINARLDAVSEVLHSESSVFGQIENHLRKLPD 620
Query: 387 LNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKH-QKLLLAVFVTPLTDLRS 445
+ R + + Q+ + + + + L + QA+ H Q LL + + +L S
Sbjct: 621 IERGLCSIYHKKCSTQEFFLIVKTLYHLKSEFQAIIPAVNSHIQSDLLRTVILEIPELLS 680
Query: 446 DFSKFQEMIETTLDM--DQVENHEFLVK-PSFDPNLSELREIMNDLEKKMQSTLISAARD 502
+ +++ D+ E + L P E++ +++++ +Q
Sbjct: 681 PVEHYLKILNEQAAKVGDKTELFKDLSDFPLIKKRKDEIQGVIDEIRMHLQEI------- 733
Query: 503 LGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSKLTSLNEE 562
++I + SAQ+ VT ++ + KN + I + VK ++K S
Sbjct: 734 ------RKILKNPSAQY-----VTVSGQEFMIEIKNSAVSCIPTDWVKVGSTKAVSRFHS 782
Query: 563 --YTKNKTEYEEAQDAIV----KEIVNISSGYVEPMQTLNDV---LAQLDAVVSFAHVSN 613
+N + ++ +V E ++ + E +L LA +D + S A V+
Sbjct: 783 PFIVENYRHLNQLREQLVLDCSAEWLDFLEKFSEHYHSLCKAVHHLATVDCIFSLAKVAK 842
Query: 614 GAPVPYVRPAILEKGQGRIILKASRHACVEVQ--DEIAFIPNDVYFEKDKQMFHIITGPN 671
Y RP + E + +I++K RH ++V ++ ++PN+ +D + IITGPN
Sbjct: 843 QGD--YCRPTVQE--ERKIVIKNGRHPVIDVLLGEQDQYVPNNTDLSEDSERVMIITGPN 898
Query: 672 MGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLE 731
MGGKS+YI+Q +I +MAQIG +VP E A + IVD I R+GA D+ KG STFM E+ +
Sbjct: 899 MGGKSSYIKQVALITIMAQIGSYVPAEEATIGIVDGIFTRMGAADNIYKGRSTFMEELTD 958
Query: 732 TASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTAL- 790
TA I+R AT SL+I+DELGRGTST+DG +A+A EY + + +F TH+ + L
Sbjct: 959 TAEIIRKATSQSLVILDELGRGTSTHDGIAIAYATLEYFIRDVKSLTLFVTHYPPVCELE 1018
Query: 791 ANQIPTVNNLHVTALTTEET--------------LTMLYQVKKGVCDQSFGIHVAELANF 836
N V N H+ L +E+ +T LYQ+ +G+ +S+G++VA+LA+
Sbjct: 1019 KNYSHQVGNYHMGFLVSEDESKLDPGAAEQVPDFVTFLYQITRGIAARSYGLNVAKLADV 1078
Query: 837 PKHVIECAKQKALELE 852
P +++ A K+ ELE
Sbjct: 1079 PGEILKKAAHKSKELE 1094
>gi|4504191 mutS homolog 6 [Homo sapiens]
Length = 1360
Score = 233 bits (595), Expect = 5e-61
Identities = 217/821 (26%), Positives = 358/821 (43%), Gaps = 112/821 (13%)
Query: 129 SQFEDILFGNNDMSASIGVVGVKMSAVDGQ---RQVGVGYVDSIQRKLGLCEFPDNDQFS 185
+Q +L G+ + S ++ +K D R GV +VD+ K + +F D+ S
Sbjct: 521 TQTYSVLEGDPSENYSKYLLSLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQFSDDRHCS 580
Query: 186 NLEALLIQIGPKECVLPGGETAGDM-----GKLRQIIQRGGILITERKKADFSTKDIYQD 240
L+ P + + G + + L +Q G I ++ A + + + ++
Sbjct: 581 RFRTLVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIPGSQFWDASKTLRTLLEE 640
Query: 241 --------------LNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNF 286
L ++LKG E + + P ++++A+S+L + +L+ D
Sbjct: 641 EYFREKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALSALGGCVFYLKKCLIDQEL 700
Query: 287 GQFELTTFDFSQYMKLDIAAVRA--------------------LNLFQGSVEDTTGSQ-- 324
L+ +F +Y+ LD V LN + + T GS
Sbjct: 701 ----LSMANFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNGSTEG 756
Query: 325 SLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRF 384
+L ++ C TP G+RL+ QW+ PL + I +RL+ +E + + + E LL++
Sbjct: 757 TLLERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVVE-LLKKL 815
Query: 385 PDLNRLAKKFQRQAANLQ-----------------------DCYRLYQGINQLPNVIQAL 421
PDL RL K + L+ D +G + +I +
Sbjct: 816 PDLERLLSKIHNVGSPLKSQNHPDSRAIMYEETTYSKKKIIDFLSALEGFKVMCKIIGIM 875
Query: 422 EK-HEGKHQKLLLAVFVTPLTDLRSDFSKFQEMI---ETTLDMDQVENHEFLV-KPSFDP 476
E+ +G K+L V + F + +T D ++ + K FD
Sbjct: 876 EEVADGFKSKILKQVISLQTKNPEGRFPDLTVELNRWDTAFDHEKARKTGLITPKAGFD- 934
Query: 477 NLSELREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNN 536
S+ + + D+ + QS L + + I + Y + E RN
Sbjct: 935 --SDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRYQLEIP--ENFTTRNL 990
Query: 537 KNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIV-----NISSGYVEP 591
+ K G K T E+ N EE +D +K+ + N Y +
Sbjct: 991 PEEYELKSTKKGCK---RYWTKTIEKKLANLINAEERRDVSLKDCMRRLFYNFDKNYKD- 1046
Query: 592 MQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAIL--EKGQGRIILKASRHACVEVQ---D 646
Q+ + +A LD ++ A+ S G P RP IL E + LK SRH C+ D
Sbjct: 1047 WQSAVECIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFLELKGSRHPCITKTFFGD 1106
Query: 647 EIAFIPNDVYF-------EKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCES 699
+ FIPND+ E K ++TGPNMGGKST +RQ G++ +MAQ+GC+VP E
Sbjct: 1107 D--FIPNDILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGLLAVMAQMGCYVPAEV 1164
Query: 700 AEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDG 759
++ +D + R+GA D + G STF E+ ETASIL AT SL+++DELGRGT+T+DG
Sbjct: 1165 CRLTPIDRVFTRLGASDRIMSGESTFFVELSETASILMHATAHSLVLVDELGRGTATFDG 1224
Query: 760 FGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALT-------TEETLT 812
+A A+ + +A I +F+TH+H L +Q V H+ + ++ET+T
Sbjct: 1225 TAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMACMVENECEDPSQETIT 1284
Query: 813 MLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQKALELEE 853
LY+ KG C +S+G + A LAN P+ VI+ +KA E E+
Sbjct: 1285 FLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKAREFEK 1325
>gi|36949366 mutS homolog 4 [Homo sapiens]
Length = 936
Score = 207 bits (528), Expect = 3e-53
Identities = 194/716 (27%), Positives = 337/716 (47%), Gaps = 51/716 (7%)
Query: 160 QVGVGYVDSIQRKLGLCEFPDNDQFSNLEALLIQIGPKECVLPGGETAGDMGKLRQIIQR 219
++G+ +D ++ L +F DN ++ + L + P E ++ TA +G ++
Sbjct: 170 EIGMASIDLKNPQIILSQFADNTTYAKVITKLKILSPLEIIM--SNTACAVGNSTKLFT- 226
Query: 220 GGILITER-KKADFSTKDIYQDLNRLLKGKKG-EQMN----SAVLPEMENQV-AVSSLSA 272
LITE K +F+T I + KG + EQ+ S VL E++++ +++++A
Sbjct: 227 ---LITENFKNVNFTT--IQRKYFNETKGLEYIEQLCIAEFSTVLMEVQSKYYCLAAVAA 281
Query: 273 VIKFLELLSDDSNFGQFELTTFDFS-QYMKLDIAAVRALNLFQGSVEDTTGSQSLAALLN 331
++K++E + + + F S Q +D ++ + L L + +D + +L +LN
Sbjct: 282 LLKYVEFIQNSVYAPKSLKICFQGSEQTAMIDSSSAQNLELLINN-QDYRNNHTLFGVLN 340
Query: 332 KCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLA 391
KTP G R + I +PL+D I RL+ V+ ++D EL LQ ++ RF D +L
Sbjct: 341 YTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQS-VISRFLDTEQLL 399
Query: 392 -------KKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTDLR 444
K+ AA + +Y + ++ L+ LL + L D R
Sbjct: 400 SVLVQIPKQDTVNAAESKITNLIY--LKHTLELVDPLKIAMKNCNTPLLRAYYGSLEDKR 457
Query: 445 SDFSKFQEMIETTLDMDQ-----VENHEFLVKPSFDPNLSELREIMNDLEKKMQSTLISA 499
F E I+T ++ D N + N++E +I ++ +
Sbjct: 458 --FGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDDIAGM 515
Query: 500 ARDLGLDPGKQIKLDSSAQFGYYFRVT--CKEEKVLRNNKNFSTVDIQKNGVKFTNSKLT 557
LG ++ S+ G++ ++T C + F + KN FT++ L
Sbjct: 516 ISQLGEKYSLPLRTSFSSARGFFIQMTTDCIALPSDQLPSEFIKISKVKNSYSFTSADLI 575
Query: 558 SLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPV 617
+NE ++ E IV ++++ ++ + L+D ++ LD ++SFAH +
Sbjct: 576 KMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSD- 634
Query: 618 PYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHIITGPNMGGKST 677
YVRP + + +K H +E I N+ Y + F IITGPNM GKST
Sbjct: 635 -YVRPEFTDT----LAIKQGWHPILEKISAEKPIANNTYVTEGSN-FLIITGPNMSGKST 688
Query: 678 YIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILR 737
Y++Q + +MAQIG +VP E + I I R+ D STFM EM E A IL
Sbjct: 689 YLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSSTFMKEMKEIAYILH 748
Query: 738 SATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTV 797
+A SLI+IDELGRGT+T +G G+ +A+ EY+ + + AF +FATHF EL + P V
Sbjct: 749 NANDKSLILIDELGRGTNTEEGIGICYAVCEYLLS-LKAFTLFATHFLELCHIDALYPNV 807
Query: 798 NNLHV------TALTTEETLTMLYQVKKGVCDQ-SFGIHVAELANFPKHVIECAKQ 846
N+H +E + Y++ KG+ ++ ++G+ AE+++ P ++ AK+
Sbjct: 808 ENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAEVSSLPPSIVLDAKE 863
>gi|4505253 mutS homolog 5 isoform c [Homo sapiens]
Length = 834
Score = 150 bits (378), Expect = 7e-36
Identities = 132/536 (24%), Positives = 233/536 (43%), Gaps = 29/536 (5%)
Query: 325 SLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFV--EDAELRQTLQEDLLR 382
SL +LN+C G++L+ W +P D + RL++++ F+ ++ ++ Q L LL
Sbjct: 253 SLFGILNRCHCKWGEKLLRLWFTRPTHDLGELSSRLDVIQFFLLPQNLDMAQMLHR-LLG 311
Query: 383 RFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTD 442
++ + K+ + + D LY+ + + A Q +F +
Sbjct: 312 HIKNVPLILKRMKLSHTKVSDWQVLYKTVYSALGLRDACRSLPQSIQ-----LFRDIAQE 366
Query: 443 LRSDFSKFQEMIETTLDMD-QVENHEFLVKPSFDPNLSELREIMNDLEKKMQSTLISAAR 501
D +I +D + + + F V P+ DP + E + + L S L AR
Sbjct: 367 FSDDLHHIASLIGKVVDFEGSLAENRFTVLPNIDPEIDEKKRRLMGLP----SFLTEVAR 422
Query: 502 DLGLDPGKQIKLDSSAQF---GYYFRVTCKEEKVLRNNKNFSTVD---IQKNGVKFTNSK 555
+ +I S G+ + V ++ + +D + + + + +++
Sbjct: 423 KELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKLHYRSAR 482
Query: 556 LTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGA 615
L+ E + + ++ ++ + + D+ ++LD +++ A S
Sbjct: 483 TKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALA--SAAR 540
Query: 616 PVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHIITGPNMGGK 675
Y RP + G + ++ RH +E+ F+PN DK +ITGPN GK
Sbjct: 541 DYGYSRPRYSPQVLG-VRIQNGRHPLMELCAR-TFVPNSTECGGDKGRVKVITGPNSSGK 598
Query: 676 STYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASI 735
S Y++Q G+I MA +G FVP E AE+ VD I R+ + +S G+STFM ++ + A
Sbjct: 599 SIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQVAKA 658
Query: 736 LRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFC---MFATHFHELT--AL 790
+ +AT SL++IDE G+GT+T DG L A+ + + G C AT+F L L
Sbjct: 659 VNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLAR-GPTCPHIFVATNFLSLVQLQL 717
Query: 791 ANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQ 846
Q P V L + L YQV +GV S H A A P ++ K+
Sbjct: 718 LPQGPLVQYLTMETCEDGNDLVFFYQVCEGVAKASHASHTAAQAGLPDKLVARGKE 773
>gi|26638662 mutS homolog 5 isoform a [Homo sapiens]
Length = 851
Score = 150 bits (378), Expect = 7e-36
Identities = 132/536 (24%), Positives = 233/536 (43%), Gaps = 29/536 (5%)
Query: 325 SLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFV--EDAELRQTLQEDLLR 382
SL +LN+C G++L+ W +P D + RL++++ F+ ++ ++ Q L LL
Sbjct: 270 SLFGILNRCHCKWGEKLLRLWFTRPTHDLGELSSRLDVIQFFLLPQNLDMAQMLHR-LLG 328
Query: 383 RFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTD 442
++ + K+ + + D LY+ + + A Q +F +
Sbjct: 329 HIKNVPLILKRMKLSHTKVSDWQVLYKTVYSALGLRDACRSLPQSIQ-----LFRDIAQE 383
Query: 443 LRSDFSKFQEMIETTLDMD-QVENHEFLVKPSFDPNLSELREIMNDLEKKMQSTLISAAR 501
D +I +D + + + F V P+ DP + E + + L S L AR
Sbjct: 384 FSDDLHHIASLIGKVVDFEGSLAENRFTVLPNIDPEIDEKKRRLMGLP----SFLTEVAR 439
Query: 502 DLGLDPGKQIKLDSSAQF---GYYFRVTCKEEKVLRNNKNFSTVD---IQKNGVKFTNSK 555
+ +I S G+ + V ++ + +D + + + + +++
Sbjct: 440 KELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKLHYRSAR 499
Query: 556 LTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGA 615
L+ E + + ++ ++ + + D+ ++LD +++ A S
Sbjct: 500 TKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALA--SAAR 557
Query: 616 PVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHIITGPNMGGK 675
Y RP + G + ++ RH +E+ F+PN DK +ITGPN GK
Sbjct: 558 DYGYSRPRYSPQVLG-VRIQNGRHPLMELCAR-TFVPNSTECGGDKGRVKVITGPNSSGK 615
Query: 676 STYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASI 735
S Y++Q G+I MA +G FVP E AE+ VD I R+ + +S G+STFM ++ + A
Sbjct: 616 SIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQVAKA 675
Query: 736 LRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFC---MFATHFHELT--AL 790
+ +AT SL++IDE G+GT+T DG L A+ + + G C AT+F L L
Sbjct: 676 VNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLAR-GPTCPHIFVATNFLSLVQLQL 734
Query: 791 ANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQ 846
Q P V L + L YQV +GV S H A A P ++ K+
Sbjct: 735 LPQGPLVQYLTMETCEDGNDLVFFYQVCEGVAKASHASHTAAQAGLPDKLVARGKE 790
>gi|26638666 mutS homolog 5 isoform c [Homo sapiens]
Length = 834
Score = 150 bits (378), Expect = 7e-36
Identities = 132/536 (24%), Positives = 233/536 (43%), Gaps = 29/536 (5%)
Query: 325 SLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFV--EDAELRQTLQEDLLR 382
SL +LN+C G++L+ W +P D + RL++++ F+ ++ ++ Q L LL
Sbjct: 253 SLFGILNRCHCKWGEKLLRLWFTRPTHDLGELSSRLDVIQFFLLPQNLDMAQMLHR-LLG 311
Query: 383 RFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTD 442
++ + K+ + + D LY+ + + A Q +F +
Sbjct: 312 HIKNVPLILKRMKLSHTKVSDWQVLYKTVYSALGLRDACRSLPQSIQ-----LFRDIAQE 366
Query: 443 LRSDFSKFQEMIETTLDMD-QVENHEFLVKPSFDPNLSELREIMNDLEKKMQSTLISAAR 501
D +I +D + + + F V P+ DP + E + + L S L AR
Sbjct: 367 FSDDLHHIASLIGKVVDFEGSLAENRFTVLPNIDPEIDEKKRRLMGLP----SFLTEVAR 422
Query: 502 DLGLDPGKQIKLDSSAQF---GYYFRVTCKEEKVLRNNKNFSTVD---IQKNGVKFTNSK 555
+ +I S G+ + V ++ + +D + + + + +++
Sbjct: 423 KELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKLHYRSAR 482
Query: 556 LTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGA 615
L+ E + + ++ ++ + + D+ ++LD +++ A S
Sbjct: 483 TKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALA--SAAR 540
Query: 616 PVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHIITGPNMGGK 675
Y RP + G + ++ RH +E+ F+PN DK +ITGPN GK
Sbjct: 541 DYGYSRPRYSPQVLG-VRIQNGRHPLMELCAR-TFVPNSTECGGDKGRVKVITGPNSSGK 598
Query: 676 STYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASI 735
S Y++Q G+I MA +G FVP E AE+ VD I R+ + +S G+STFM ++ + A
Sbjct: 599 SIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQVAKA 658
Query: 736 LRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFC---MFATHFHELT--AL 790
+ +AT SL++IDE G+GT+T DG L A+ + + G C AT+F L L
Sbjct: 659 VNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLAR-GPTCPHIFVATNFLSLVQLQL 717
Query: 791 ANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQ 846
Q P V L + L YQV +GV S H A A P ++ K+
Sbjct: 718 LPQGPLVQYLTMETCEDGNDLVFFYQVCEGVAKASHASHTAAQAGLPDKLVARGKE 773
>gi|26638664 mutS homolog 5 isoform b [Homo sapiens]
Length = 835
Score = 145 bits (367), Expect = 1e-34
Identities = 132/537 (24%), Positives = 233/537 (43%), Gaps = 30/537 (5%)
Query: 325 SLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFV--EDAELRQTLQEDLLR 382
SL +LN+C G++L+ W +P D + RL++++ F+ ++ ++ Q L LL
Sbjct: 253 SLFGILNRCHCKWGEKLLRLWFTRPTHDLGELSSRLDVIQFFLLPQNLDMAQMLHR-LLG 311
Query: 383 RFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTD 442
++ + K+ + + D LY+ + + A Q +F +
Sbjct: 312 HIKNVPLILKRMKLSHTKVSDWQVLYKTVYSALGLRDACRSLPQSIQ-----LFRDIAQE 366
Query: 443 LRSDFSKFQEMIETTLDMD-QVENHEFLVKPSFDPNLSELREIMNDLEKKMQSTLISAAR 501
D +I +D + + + F V P+ DP + E + + L S L AR
Sbjct: 367 FSDDLHHIASLIGKVVDFEGSLAENRFTVLPNIDPEIDEKKRRLMGLP----SFLTEVAR 422
Query: 502 DLGLDPGKQIKLDSSAQF---GYYFRVTCKEEKVLRNNKNFSTVD---IQKNGVKFTNSK 555
+ +I S G+ + V ++ + +D + + + + +++
Sbjct: 423 KELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKLHYRSAR 482
Query: 556 LTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGA 615
L+ E + + ++ ++ + + D+ ++LD +++ A S
Sbjct: 483 TKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALA--SAAR 540
Query: 616 PVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHIITGPNMGGK 675
Y RP + G + ++ RH +E+ F+PN DK +ITGPN GK
Sbjct: 541 DYGYSRPRYSPQVLG-VRIQNGRHPLMELCAR-TFVPNSTECGGDKGRVKVITGPNSSGK 598
Query: 676 STYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEM-LETAS 734
S Y++Q G+I MA +G FVP E AE+ VD I R+ + +S G+STFM ++ + A
Sbjct: 599 SIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQQVAK 658
Query: 735 ILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFC---MFATHFHELT--A 789
+ +AT SL++IDE G+GT+T DG L A+ + + G C AT+F L
Sbjct: 659 AVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLAR-GPTCPHIFVATNFLSLVQLQ 717
Query: 790 LANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQ 846
L Q P V L + L YQV +GV S H A A P ++ K+
Sbjct: 718 LLPQGPLVQYLTMETCEDGNDLVFFYQVCEGVAKASHASHTAAQAGLPDKLVARGKE 774
>gi|224451082 cytospin A [Homo sapiens]
Length = 1117
Score = 39.7 bits (91), Expect = 0.013
Identities = 67/314 (21%), Positives = 126/314 (40%), Gaps = 52/314 (16%)
Query: 352 DKNRIEERLNLVEAFVEDAE-LRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQ- 409
DK+ I++ L V E AE L +LQEDL D NRL Q A ++D YR +Q
Sbjct: 601 DKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRL----QDAIAKVEDEYRAFQE 656
Query: 410 -GINQLPNVIQALEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLDM-DQVEN-- 465
Q+ ++ LEK +DL ++ +M ET ++ D+VE
Sbjct: 657 EAKKQIEDLNMTLEKLR---------------SDLDEKETERSDMKETIFELEDEVEQHR 701
Query: 466 ----HEFLVKPSFDPNLSELREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGY 521
H+ L+ + + +L++ +D+E++++ + R L + + + + Q
Sbjct: 702 AVKLHDNLIISDLENTVKKLQDQKHDMEREIK----TLHRRLREESAEWRQFQADLQTAV 757
Query: 522 YFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQ-----DA 576
K E + + + + + N KLT EE K E E + +A
Sbjct: 758 VIANDIKSEA----QEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNA 813
Query: 577 IVKEIVNI---------SSGYVEPMQTLNDVLAQLDAVVSFAHVSNGA-PVPYVRPAILE 626
+ +++ + SS EP T+ ++ D+ + + A P + P+ ++
Sbjct: 814 VERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQVPNPAAAAIPRTPLSPSPMK 873
Query: 627 KGQGRIILKASRHA 640
+ RH+
Sbjct: 874 TPPAAAVSPMQRHS 887
>gi|224451080 cytospin A [Homo sapiens]
Length = 1117
Score = 39.7 bits (91), Expect = 0.013
Identities = 67/314 (21%), Positives = 126/314 (40%), Gaps = 52/314 (16%)
Query: 352 DKNRIEERLNLVEAFVEDAE-LRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQ- 409
DK+ I++ L V E AE L +LQEDL D NRL Q A ++D YR +Q
Sbjct: 601 DKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRL----QDAIAKVEDEYRAFQE 656
Query: 410 -GINQLPNVIQALEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLDM-DQVEN-- 465
Q+ ++ LEK +DL ++ +M ET ++ D+VE
Sbjct: 657 EAKKQIEDLNMTLEKLR---------------SDLDEKETERSDMKETIFELEDEVEQHR 701
Query: 466 ----HEFLVKPSFDPNLSELREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGY 521
H+ L+ + + +L++ +D+E++++ + R L + + + + Q
Sbjct: 702 AVKLHDNLIISDLENTVKKLQDQKHDMEREIK----TLHRRLREESAEWRQFQADLQTAV 757
Query: 522 YFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQ-----DA 576
K E + + + + + N KLT EE K E E + +A
Sbjct: 758 VIANDIKSEA----QEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNA 813
Query: 577 IVKEIVNI---------SSGYVEPMQTLNDVLAQLDAVVSFAHVSNGA-PVPYVRPAILE 626
+ +++ + SS EP T+ ++ D+ + + A P + P+ ++
Sbjct: 814 VERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQVPNPAAAAIPRTPLSPSPMK 873
Query: 627 KGQGRIILKASRHA 640
+ RH+
Sbjct: 874 TPPAAAVSPMQRHS 887
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 38.5 bits (88), Expect = 0.029
Identities = 48/236 (20%), Positives = 99/236 (41%), Gaps = 14/236 (5%)
Query: 353 KNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAA--NLQDCYRLYQG 410
+ +E+++ +E +E +EL + D + AK+ R+ LQ+ + Q
Sbjct: 1157 RGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQL 1216
Query: 411 INQLPNVIQALEKHEG--KHQKLLLAVFVTPLTDLRSDFSKFQEMIETT-LDMDQVENHE 467
++ Q +++ E K Q+ +A DL + +E ++ + ++ + + +
Sbjct: 1217 KKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQ 1276
Query: 468 FLVKPSFDPNLSELREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTC 527
+ + SEL + M L K+ + A +LG ++ L++ Q +
Sbjct: 1277 VQAQREIERLSSELED-MKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAE--IKKLS 1333
Query: 528 KEEKVLRNNKNFSTVDIQKNGVKFT------NSKLTSLNEEYTKNKTEYEEAQDAI 577
E + L+ + + Q+N K+ S + LNE+ K K E EEAQD +
Sbjct: 1334 AEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTV 1389
>gi|197304777 TBC1 domain family, member 5 isoform a [Homo sapiens]
Length = 817
Score = 34.7 bits (78), Expect = 0.43
Identities = 37/127 (29%), Positives = 59/127 (46%), Gaps = 17/127 (13%)
Query: 347 KQPLMDKNRI-EERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCY 405
+Q LM N + ++ +L F +D ELR +++D+ R FP++ ++ R+ L D
Sbjct: 133 QQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQENVRKI--LTDVL 190
Query: 406 RLYQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTDLRSDFSKF---QEMIETTLDMDQ 462
Y N+ Q L K +G H+ L VFV L D F E + + +M
Sbjct: 191 FCYARENE-----QLLYK-QGMHELLAPIVFV-----LHCDHQAFLHASESAQPSEEMKT 239
Query: 463 VENHEFL 469
V N E+L
Sbjct: 240 VLNPEYL 246
>gi|197304775 TBC1 domain family, member 5 isoform b [Homo sapiens]
Length = 795
Score = 34.7 bits (78), Expect = 0.43
Identities = 37/127 (29%), Positives = 59/127 (46%), Gaps = 17/127 (13%)
Query: 347 KQPLMDKNRI-EERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCY 405
+Q LM N + ++ +L F +D ELR +++D+ R FP++ ++ R+ L D
Sbjct: 133 QQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQENVRKI--LTDVL 190
Query: 406 RLYQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTDLRSDFSKF---QEMIETTLDMDQ 462
Y N+ Q L K +G H+ L VFV L D F E + + +M
Sbjct: 191 FCYARENE-----QLLYK-QGMHELLAPIVFV-----LHCDHQAFLHASESAQPSEEMKT 239
Query: 463 VENHEFL 469
V N E+L
Sbjct: 240 VLNPEYL 246
>gi|7661998 TBC1 domain family, member 5 isoform b [Homo sapiens]
Length = 795
Score = 34.7 bits (78), Expect = 0.43
Identities = 37/127 (29%), Positives = 59/127 (46%), Gaps = 17/127 (13%)
Query: 347 KQPLMDKNRI-EERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCY 405
+Q LM N + ++ +L F +D ELR +++D+ R FP++ ++ R+ L D
Sbjct: 133 QQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQENVRKI--LTDVL 190
Query: 406 RLYQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTDLRSDFSKF---QEMIETTLDMDQ 462
Y N+ Q L K +G H+ L VFV L D F E + + +M
Sbjct: 191 FCYARENE-----QLLYK-QGMHELLAPIVFV-----LHCDHQAFLHASESAQPSEEMKT 239
Query: 463 VENHEFL 469
V N E+L
Sbjct: 240 VLNPEYL 246
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 34.7 bits (78), Expect = 0.43
Identities = 80/420 (19%), Positives = 162/420 (38%), Gaps = 59/420 (14%)
Query: 233 STKDIYQDLNRLLKGKKGEQMNSAVLPEMENQVAVS---------------SLSAVIKFL 277
S + QDL ++G +Q N + +NQ V+ SLS +
Sbjct: 1751 SLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPT 1810
Query: 278 ELLSDDSNFGQFELTTFDFSQY-------MKLDIAAVRALNLFQGSVEDTTGSQSLA--- 327
S S + DFS + ++D R L + ++ SQ+L
Sbjct: 1811 CSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEK 1870
Query: 328 -ALLNKCKTPQGQ-RLVNQWIKQPLMDKNRIEERLNLVEAFVEDAEL-RQTLQEDLLRRF 384
LL++ T G+ +++ + + + + +I+E L+ V E AE + L+E L+ +
Sbjct: 1871 NTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQL 1930
Query: 385 PDLNRLAKKFQRQAANLQ--------DCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVF 436
+LN + + + Q + L + +++L Q L K + K + + +
Sbjct: 1931 AELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1990
Query: 437 VTPLTDL------RSDFSKFQEMIETT------LDMDQVENHEFLVKPSFDPNLSELREI 484
+ + +S + QE+++ L D + E + + + + L +
Sbjct: 1991 LEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKI--SALERTVKALEFV 2048
Query: 485 MNDLEKKMQSTLISAARDLGLDPGKQIKL--------DSSAQFGYYFRVTCKEEKVLRNN 536
+ +K ++ T + A+ + Q +L D+ ++ K +K L++N
Sbjct: 2049 QTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSN 2108
Query: 537 KNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLN 596
K S K + +L E++ K K +E DA+ +E V++ E TLN
Sbjct: 2109 KE-SVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLN 2167
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
sapiens]
Length = 1478
Score = 33.5 bits (75), Expect = 0.95
Identities = 65/297 (21%), Positives = 117/297 (39%), Gaps = 49/297 (16%)
Query: 139 NDMSASIGVVGVKMSAVDGQR-------QVGVGYVDSIQRKLGLCEFPDNDQFSNLEALL 191
+D + + +G K+ A++ +R + ++ + ++L L E D ++LE L+
Sbjct: 394 SDAAQEMQELGEKLQALERERTKVEEVNRQQSAQLEQLVKELQLKE----DARASLERLV 449
Query: 192 IQIGPKECVLPGGETAGDMGKLRQIIQRGGILITERKKADFSTKDIYQDLNRLLKGKKGE 251
++ P + L G D Q+ +R L+ T ++L L + KK +
Sbjct: 450 KEMAPLQEELSGKGQEAD-----QLWRRLQELLAH-------TSSWEEELAELRREKKQQ 497
Query: 252 QMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYMKLDIAAVRALN 311
Q +L + V SL+ ++FLE + Q D + K I L+
Sbjct: 498 QEEKELLEQ-----EVRSLTRQLQFLE-----TQLAQVSQHVSDLEEQKKQLIQDKDHLS 547
Query: 312 LFQGSVEDTTGSQS----LAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFV 367
G +E G +A N+ P L W K EE+ L EA +
Sbjct: 548 QQVGMLERLAGPPGPELPVAGEKNEALVPVNSSLQEAWGKPE-------EEQRGLQEAQL 600
Query: 368 EDAELRQTLQEDLLRRF-----PDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQ 419
+D ++++ QE+ LR+ +L + + Q LQ YQ + Q + IQ
Sbjct: 601 DDTKVQEGSQEEELRQANRELEKELQNVVGRNQLLEGKLQALQADYQALQQRESAIQ 657
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 33.5 bits (75), Expect = 0.95
Identities = 53/236 (22%), Positives = 93/236 (39%), Gaps = 29/236 (12%)
Query: 375 TLQEDLLRR-FPDLNRLAKKFQRQAANLQDCYRLYQGI-NQLPNVIQALE-KHEGKHQKL 431
TL + + RR F RL K +R A L D + + N P+ + + K++ + +
Sbjct: 1638 TLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEF 1697
Query: 432 LLAVFV-------TPLTDLR---SDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSEL 481
A V + DL D +K + +E L Q E +E L E
Sbjct: 1698 TCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEI------QNRLEED 1751
Query: 482 REIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFST 541
+E MN+L KK ++ + A+RDL Q +L+ + KE++ L+
Sbjct: 1752 QEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEAN----------KEKQELQEKLQALQ 1801
Query: 542 VDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLND 597
++ + L S E + E + VK + +++S E M+ L +
Sbjct: 1802 SQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTE 1857
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 33.5 bits (75), Expect = 0.95
Identities = 53/236 (22%), Positives = 93/236 (39%), Gaps = 29/236 (12%)
Query: 375 TLQEDLLRR-FPDLNRLAKKFQRQAANLQDCYRLYQGI-NQLPNVIQALE-KHEGKHQKL 431
TL + + RR F RL K +R A L D + + N P+ + + K++ + +
Sbjct: 1638 TLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEF 1697
Query: 432 LLAVFV-------TPLTDLR---SDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSEL 481
A V + DL D +K + +E L Q E +E L E
Sbjct: 1698 TCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEI------QNRLEED 1751
Query: 482 REIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFST 541
+E MN+L KK ++ + A+RDL Q +L+ + KE++ L+
Sbjct: 1752 QEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEAN----------KEKQELQEKLQALQ 1801
Query: 542 VDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLND 597
++ + L S E + E + VK + +++S E M+ L +
Sbjct: 1802 SQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTE 1857
>gi|24308171 zinc finger protein 280C [Homo sapiens]
Length = 737
Score = 33.5 bits (75), Expect = 0.95
Identities = 26/99 (26%), Positives = 40/99 (40%), Gaps = 5/99 (5%)
Query: 475 DPNLSELREIMNDLEKKMQSTLISAARDLGLDP-----GKQIKLDSSAQFGYYFRVTCKE 529
DP ++ D+ K ++ + R D GK I L + +G + VT KE
Sbjct: 250 DPLKYHMKHCCPDMITKFLGVIVKSERPCDEDKTDSETGKLIMLVNEFYYGRHEGVTEKE 309
Query: 530 EKVLRNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKT 568
K K FS + KN ++F N L E N++
Sbjct: 310 PKTYTTFKCFSCSKVLKNNIRFMNHMKHHLELEKQNNES 348
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 33.1 bits (74), Expect = 1.2
Identities = 17/52 (32%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
Query: 875 LEREQGEKIIQ---EFLSKVKQMPFTEMSEENITIKLKQLKAEVIAKNNSFV 923
LE E+ E++++ E K P +E SEE + K +L +++ KN+ FV
Sbjct: 1773 LEEEEEEEVVENDEEIAFSGKDKPASENSEEKLISKFDKLPVKIVQKNDPFV 1824
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 33.1 bits (74), Expect = 1.2
Identities = 17/52 (32%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
Query: 875 LEREQGEKIIQ---EFLSKVKQMPFTEMSEENITIKLKQLKAEVIAKNNSFV 923
LE E+ E++++ E K P +E SEE + K +L +++ KN+ FV
Sbjct: 1556 LEEEEEEEVVENDEEIAFSGKDKPASENSEEKLISKFDKLPVKIVQKNDPFV 1607
>gi|151101140 coiled-coil domain containing 2 isoform a [Homo
sapiens]
Length = 600
Score = 33.1 bits (74), Expect = 1.2
Identities = 103/480 (21%), Positives = 198/480 (41%), Gaps = 73/480 (15%)
Query: 204 GETAGDMGKLRQIIQRGGILITERKKADFSTKDIYQDLNRLLKGKKGEQMNSAVLPEMEN 263
G G G RQI+ + L R K T ++ N+L KG + ++V E
Sbjct: 79 GMKTGTKGPQRQILDKSYYLGLLRSKISELTTEV----NKLQKGIEMYNQENSVYLSYEK 134
Query: 264 QVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYMKLDIAAVRALNLFQGSVEDTTGS 323
+ +L+ IK L+ D N +L T + + D ++A N +
Sbjct: 135 RA--ETLAVEIKELQGQLADYNMLVDKLNTNTEMEEVMNDYNMLKAQN--------DRET 184
Query: 324 QSLAALLNKCKTPQGQ-RLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQT----LQE 378
QSL + + + + Q R V + I+Q + I + ++ E V+ E++ T LQE
Sbjct: 185 QSLDVIFTERQAKEKQIRSVEEEIEQEKQATDDIIKNMSF-ENQVKYLEMKTTNEKLLQE 243
Query: 379 -DLLRRFPDLNRLAKK----------FQRQAANLQD-CYRLYQGINQLPNVIQALEKHEG 426
D L++ D + K+ +++A L + Y L +Q+ +++
Sbjct: 244 LDTLQQQLDSQNMKKESLEAEIAHSQVKQEAVLLHEKLYELESHRDQMIAEDKSIGSPME 303
Query: 427 KHQKLL---------LAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPN 477
+ +KLL +A LTD + ++F E I LDMD +E H+ + +
Sbjct: 304 EREKLLKQIKDDNQEIASMERQLTDTKEKINQFIEEIRQ-LDMD-LEEHQGEMNQKYK-E 360
Query: 478 LSELREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFR----------VTC 527
L + E M+ + + T ++ L QI+ + A + R +T
Sbjct: 361 LKKREEHMDTFIETFEET-----KNQELKRKAQIEANIVALLEHCSRNINRIEQISSITN 415
Query: 528 KEEKVLRNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSG 587
+E K+++++ NF + ++QK+ + T LTS + + + E + + +E ++ S
Sbjct: 416 QELKMMQDDLNFKSTEVQKS--QSTAQNLTSDIQRLQLDLQKMELLESKMTEEQHSLKS- 472
Query: 588 YVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDE 647
++ M T ++ L A+ S I + Q R+IL R+A ++ ++
Sbjct: 473 KIKQMTTDLEIYNDLPALKSSG-----------EEKIKKLHQERMILSTHRNAFKKIMEK 521
>gi|151105223 coiled-coil domain containing 2 isoform a [Homo
sapiens]
Length = 600
Score = 33.1 bits (74), Expect = 1.2
Identities = 103/480 (21%), Positives = 198/480 (41%), Gaps = 73/480 (15%)
Query: 204 GETAGDMGKLRQIIQRGGILITERKKADFSTKDIYQDLNRLLKGKKGEQMNSAVLPEMEN 263
G G G RQI+ + L R K T ++ N+L KG + ++V E
Sbjct: 79 GMKTGTKGPQRQILDKSYYLGLLRSKISELTTEV----NKLQKGIEMYNQENSVYLSYEK 134
Query: 264 QVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYMKLDIAAVRALNLFQGSVEDTTGS 323
+ +L+ IK L+ D N +L T + + D ++A N +
Sbjct: 135 RA--ETLAVEIKELQGQLADYNMLVDKLNTNTEMEEVMNDYNMLKAQN--------DRET 184
Query: 324 QSLAALLNKCKTPQGQ-RLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQT----LQE 378
QSL + + + + Q R V + I+Q + I + ++ E V+ E++ T LQE
Sbjct: 185 QSLDVIFTERQAKEKQIRSVEEEIEQEKQATDDIIKNMSF-ENQVKYLEMKTTNEKLLQE 243
Query: 379 -DLLRRFPDLNRLAKK----------FQRQAANLQD-CYRLYQGINQLPNVIQALEKHEG 426
D L++ D + K+ +++A L + Y L +Q+ +++
Sbjct: 244 LDTLQQQLDSQNMKKESLEAEIAHSQVKQEAVLLHEKLYELESHRDQMIAEDKSIGSPME 303
Query: 427 KHQKLL---------LAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPN 477
+ +KLL +A LTD + ++F E I LDMD +E H+ + +
Sbjct: 304 EREKLLKQIKDDNQEIASMERQLTDTKEKINQFIEEIRQ-LDMD-LEEHQGEMNQKYK-E 360
Query: 478 LSELREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFR----------VTC 527
L + E M+ + + T ++ L QI+ + A + R +T
Sbjct: 361 LKKREEHMDTFIETFEET-----KNQELKRKAQIEANIVALLEHCSRNINRIEQISSITN 415
Query: 528 KEEKVLRNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSG 587
+E K+++++ NF + ++QK+ + T LTS + + + E + + +E ++ S
Sbjct: 416 QELKMMQDDLNFKSTEVQKS--QSTAQNLTSDIQRLQLDLQKMELLESKMTEEQHSLKS- 472
Query: 588 YVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDE 647
++ M T ++ L A+ S I + Q R+IL R+A ++ ++
Sbjct: 473 KIKQMTTDLEIYNDLPALKSSG-----------EEKIKKLHQERMILSTHRNAFKKIMEK 521
>gi|151105229 coiled-coil domain containing 2 isoform a [Homo
sapiens]
Length = 600
Score = 33.1 bits (74), Expect = 1.2
Identities = 103/480 (21%), Positives = 198/480 (41%), Gaps = 73/480 (15%)
Query: 204 GETAGDMGKLRQIIQRGGILITERKKADFSTKDIYQDLNRLLKGKKGEQMNSAVLPEMEN 263
G G G RQI+ + L R K T ++ N+L KG + ++V E
Sbjct: 79 GMKTGTKGPQRQILDKSYYLGLLRSKISELTTEV----NKLQKGIEMYNQENSVYLSYEK 134
Query: 264 QVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYMKLDIAAVRALNLFQGSVEDTTGS 323
+ +L+ IK L+ D N +L T + + D ++A N +
Sbjct: 135 RA--ETLAVEIKELQGQLADYNMLVDKLNTNTEMEEVMNDYNMLKAQN--------DRET 184
Query: 324 QSLAALLNKCKTPQGQ-RLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQT----LQE 378
QSL + + + + Q R V + I+Q + I + ++ E V+ E++ T LQE
Sbjct: 185 QSLDVIFTERQAKEKQIRSVEEEIEQEKQATDDIIKNMSF-ENQVKYLEMKTTNEKLLQE 243
Query: 379 -DLLRRFPDLNRLAKK----------FQRQAANLQD-CYRLYQGINQLPNVIQALEKHEG 426
D L++ D + K+ +++A L + Y L +Q+ +++
Sbjct: 244 LDTLQQQLDSQNMKKESLEAEIAHSQVKQEAVLLHEKLYELESHRDQMIAEDKSIGSPME 303
Query: 427 KHQKLL---------LAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPN 477
+ +KLL +A LTD + ++F E I LDMD +E H+ + +
Sbjct: 304 EREKLLKQIKDDNQEIASMERQLTDTKEKINQFIEEIRQ-LDMD-LEEHQGEMNQKYK-E 360
Query: 478 LSELREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFR----------VTC 527
L + E M+ + + T ++ L QI+ + A + R +T
Sbjct: 361 LKKREEHMDTFIETFEET-----KNQELKRKAQIEANIVALLEHCSRNINRIEQISSITN 415
Query: 528 KEEKVLRNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSG 587
+E K+++++ NF + ++QK+ + T LTS + + + E + + +E ++ S
Sbjct: 416 QELKMMQDDLNFKSTEVQKS--QSTAQNLTSDIQRLQLDLQKMELLESKMTEEQHSLKS- 472
Query: 588 YVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDE 647
++ M T ++ L A+ S I + Q R+IL R+A ++ ++
Sbjct: 473 KIKQMTTDLEIYNDLPALKSSG-----------EEKIKKLHQERMILSTHRNAFKKIMEK 521
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 33.1 bits (74), Expect = 1.2
Identities = 57/281 (20%), Positives = 116/281 (41%), Gaps = 46/281 (16%)
Query: 353 KNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLY-QGI 411
KN+I VEA + AEL + ++LLR LN+ K D +L+ Q
Sbjct: 355 KNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAK 414
Query: 412 NQLPNVIQALEKHEGKHQKLLLAV------FVTPLTDLRSD---------------FSKF 450
L IQ + K +K++ + ++ +DL F
Sbjct: 415 RNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDYR 474
Query: 451 QEMIETTLDMDQVENHEFLVKPS---FDPNLSELREIMNDLEKKMQSTLISAARDLGLDP 507
+++ E+ + + Q +N V+ + NL E ++ + D+++K++ + +
Sbjct: 475 KKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLK---------IMIHQ 525
Query: 508 GKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNK 567
++K D SA KE +++ + ++ +K +K KL E TK+
Sbjct: 526 VDELKEDISA----------KESALVKLHLEQQRIEKEKETLKAELQKLRQQALE-TKHF 574
Query: 568 TEYEEAQDAIVKEIVNISSG-YVEPMQTLNDVLAQLDAVVS 607
E +EA++ + I+ + G + + L+ V+++ D + S
Sbjct: 575 IEKQEAEERKLLRIIAEADGERLRQKKELDQVISERDILGS 615
>gi|34850061 superiorcervical ganglia, neural specific 10 [Homo
sapiens]
Length = 179
Score = 32.7 bits (73), Expect = 1.6
Identities = 29/107 (27%), Positives = 54/107 (50%), Gaps = 17/107 (15%)
Query: 816 QVKKGVCDQSFGIHV---AELANFPKHVIECAKQKALELEEFQYIGE-------SQGYDI 865
Q+ K Q+F + + + ++ P+ + K+K L LEE Q E SQ +
Sbjct: 44 QINKRASGQAFELILKPPSPISEAPR-TLASPKKKDLSLEEIQKKLEAAEERRKSQEAQV 102
Query: 866 MEPAAKKCYLEREQGEKIIQEFLSKVKQMPFTEMSEENITIKLKQLK 912
++ A+K ERE +K ++E F++M+EE + +K++Q+K
Sbjct: 103 LKQLAEKREHEREVLQKALEE------NNNFSKMAEEKLILKMEQIK 143
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 32.3 bits (72), Expect = 2.1
Identities = 57/278 (20%), Positives = 105/278 (37%), Gaps = 62/278 (22%)
Query: 368 EDAELRQTLQ--EDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGIN-----QLPNVIQA 420
+D E+ Q Q E L + D L +R N+Q Q N ++ V+QA
Sbjct: 435 KDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQA 494
Query: 421 LEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSE 480
LE+ LAV + D +K E++ L N + S D L +
Sbjct: 495 LEE---------LAVNYDQKSQEVEDKTKEYELLSDEL------NQKSATLASIDAELQK 539
Query: 481 LREIMNDLEKK---MQSTLISAARDLGLDPGKQ--IKLDSSAQFGYYFRVT--------- 526
L+E+ N +K+ M ++L+ ++G+ G + + + F V
Sbjct: 540 LKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKS 599
Query: 527 --------CKE---------EKVLRNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTE 569
CK+ +K+ N K + ++ + + LT + + K +
Sbjct: 600 EVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQ 659
Query: 570 YEEAQDAIVKEIVNI---------SSGYVEPMQTLNDV 598
EE+ DA+ +E+V + ++ +QT N+V
Sbjct: 660 LEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEV 697
>gi|50083279 centrosome protein 4 [Homo sapiens]
Length = 1140
Score = 32.3 bits (72), Expect = 2.1
Identities = 56/246 (22%), Positives = 102/246 (41%), Gaps = 38/246 (15%)
Query: 376 LQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKH--------EGK 427
L+E + +L KK R+ A+L+ NQ + ++ LEK +
Sbjct: 92 LREHSDQHVKELKTSLKKCARETADLKFLN------NQYAHKLKLLEKESKAKNERIQQL 145
Query: 428 HQKLLLAVFVTPLTDLRSDFSKFQEM-IETTLDMDQVENHEFLVKPSFDPNLSELREIMN 486
+K L AV TP RS + Q M I+ + +V ++ V DP +++L ++ +
Sbjct: 146 QEKNLHAVVQTPGGKKRSIAFRRQRMQIDEPVPPSEVSSYP--VPQPDDPYIADLLQVAD 203
Query: 487 DLEKKMQSTLISAARDLGL------DPGKQI--------KLDSSAQFGYYFRVTCKEEKV 532
+ +++Q + L + D KQI +L + G V E +
Sbjct: 204 NRIQELQQEVHQLQEKLAMMESGVRDYSKQIELREREIERLSVALDGGRSPDVLSLESRN 263
Query: 533 LRNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPM 592
N K + ++IQ V F L N++ K E E ++ + E+VN+S+ +
Sbjct: 264 KTNEKLIAHLNIQ---VDF----LQQANKDLEKRIRELMETKETVTSEVVNLSNKNEKLC 316
Query: 593 QTLNDV 598
Q L ++
Sbjct: 317 QELTEI 322
Score = 32.0 bits (71), Expect = 2.8
Identities = 33/160 (20%), Positives = 69/160 (43%), Gaps = 13/160 (8%)
Query: 350 LMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCY-RLY 408
L +N+ E+L + + Q +DL +R +L + + NL + +L
Sbjct: 259 LESRNKTNEKL--IAHLNIQVDFLQQANKDLEKRIRELMETKETVTSEVVNLSNKNEKLC 316
Query: 409 QGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETT------LDMDQ 462
Q + ++ + Q LE+H+ + + +++ S+ Q++ ET L++ Q
Sbjct: 317 QELTEIDQLAQQLERHKEEVLETADKELGEAKKEIKRKLSEMQDLEETMAKLQLELNLCQ 376
Query: 463 VENH----EFLVKPSFDPNLSELREIMNDLEKKMQSTLIS 498
E E LVK + + +L + L KK++S ++
Sbjct: 377 KEKERLSDELLVKSDLETVVHQLEQEKQRLSKKVESFAVT 416
>gi|225690497 tight junction associated protein 1 isoform b [Homo
sapiens]
Length = 547
Score = 32.0 bits (71), Expect = 2.8
Identities = 37/136 (27%), Positives = 59/136 (43%), Gaps = 13/136 (9%)
Query: 354 NRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQ 413
+R+E+ L +A E +L Q E+L RR R + +R+ QDC L G ++
Sbjct: 28 SRLEQEEPLTDA--ERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSR 85
Query: 414 LPNVIQALEKHEGKHQKLLLAVFVT-----PLTDLRSDFSKFQEMIETTLDMDQVE-NHE 467
+ L+K + K ++L + + L D K EM TLD + VE ++
Sbjct: 86 -----EELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLIKKAEMDRKTLDWEIVELTNK 140
Query: 468 FLVKPSFDPNLSELRE 483
L + L EL E
Sbjct: 141 LLDAKNTINKLEELNE 156
>gi|225690495 tight junction associated protein 1 isoform b [Homo
sapiens]
Length = 547
Score = 32.0 bits (71), Expect = 2.8
Identities = 37/136 (27%), Positives = 59/136 (43%), Gaps = 13/136 (9%)
Query: 354 NRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQ 413
+R+E+ L +A E +L Q E+L RR R + +R+ QDC L G ++
Sbjct: 28 SRLEQEEPLTDA--ERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSR 85
Query: 414 LPNVIQALEKHEGKHQKLLLAVFVT-----PLTDLRSDFSKFQEMIETTLDMDQVE-NHE 467
+ L+K + K ++L + + L D K EM TLD + VE ++
Sbjct: 86 -----EELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLIKKAEMDRKTLDWEIVELTNK 140
Query: 468 FLVKPSFDPNLSELRE 483
L + L EL E
Sbjct: 141 LLDAKNTINKLEELNE 156
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,612,839
Number of Sequences: 37866
Number of extensions: 1266887
Number of successful extensions: 3619
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 3568
Number of HSP's gapped (non-prelim): 81
length of query: 934
length of database: 18,247,518
effective HSP length: 112
effective length of query: 822
effective length of database: 14,006,526
effective search space: 11513364372
effective search space used: 11513364372
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.