Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 4557467
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557467 excision repair cross-complementing rodent repair
deficiency, complementation group 8 isoform 1 [Homo sapiens]
(396 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557467 excision repair cross-complementing rodent repair def... 820 0.0
gi|113865883 WD repeat domain 38 [Homo sapiens] 81 1e-15
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H... 75 8e-14
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H... 75 8e-14
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H... 75 8e-14
gi|21071067 TBP-associated factor 5 [Homo sapiens] 72 7e-13
gi|16554629 WD repeat domain 5 [Homo sapiens] 71 2e-12
gi|16554627 WD repeat domain 5 [Homo sapiens] 71 2e-12
gi|32189425 WD repeat domain 69 [Homo sapiens] 69 6e-12
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 69 7e-12
gi|118402582 cell division cycle 20 [Homo sapiens] 69 1e-11
gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapi... 68 1e-11
gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] 68 2e-11
gi|19913367 transducin beta-like 1Y [Homo sapiens] 67 2e-11
gi|19913365 transducin beta-like 1Y [Homo sapiens] 67 2e-11
gi|15150805 transducin beta-like 1Y [Homo sapiens] 67 2e-11
gi|8923881 WD SOCS-box protein 2 [Homo sapiens] 67 3e-11
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 67 4e-11
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 67 4e-11
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 67 4e-11
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 67 4e-11
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 67 4e-11
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 67 4e-11
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 67 4e-11
gi|23199987 WD repeat domain 5B [Homo sapiens] 67 4e-11
gi|102470001 PQQ repeat and WD repeat domain containing [Homo sa... 66 5e-11
gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ... 65 8e-11
gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo ... 64 3e-10
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 63 5e-10
gi|4557515 damage-specific DNA binding protein 2 [Homo sapiens] 62 7e-10
>gi|4557467 excision repair cross-complementing rodent repair
deficiency, complementation group 8 isoform 1 [Homo
sapiens]
Length = 396
Score = 820 bits (2118), Expect = 0.0
Identities = 396/396 (100%), Positives = 396/396 (100%)
Query: 1 MLGFLSARQTGLEDPLRLRRAESTRRVLGLELNKDRDVERIHGGGINTLDIEPVEGRYML 60
MLGFLSARQTGLEDPLRLRRAESTRRVLGLELNKDRDVERIHGGGINTLDIEPVEGRYML
Sbjct: 1 MLGFLSARQTGLEDPLRLRRAESTRRVLGLELNKDRDVERIHGGGINTLDIEPVEGRYML 60
Query: 61 SGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYSVETVQWYPHDTGMFTSSSF 120
SGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYSVETVQWYPHDTGMFTSSSF
Sbjct: 61 SGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYSVETVQWYPHDTGMFTSSSF 120
Query: 121 DKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCLVAVGTRGPKVQLCDLKSGSCSH 180
DKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCLVAVGTRGPKVQLCDLKSGSCSH
Sbjct: 121 DKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCLVAVGTRGPKVQLCDLKSGSCSH 180
Query: 181 ILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESA 240
ILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESA
Sbjct: 181 ILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESA 240
Query: 241 NTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKFTVS 300
NTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKFTVS
Sbjct: 241 NTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKFTVS 300
Query: 301 CGCSSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILA 360
CGCSSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILA
Sbjct: 301 CGCSSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILA 360
Query: 361 WVPSLYEPVPDDDETTTKSQLNPAFEDAWSSSDEEG 396
WVPSLYEPVPDDDETTTKSQLNPAFEDAWSSSDEEG
Sbjct: 361 WVPSLYEPVPDDDETTTKSQLNPAFEDAWSSSDEEG 396
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 81.3 bits (199), Expect = 1e-15
Identities = 81/315 (25%), Positives = 136/315 (43%), Gaps = 39/315 (12%)
Query: 42 HGGGINTLDIEPVEGRYMLSGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYS 101
HGG +N+ P +G+ +L+G DG + Y E S Q + H
Sbjct: 20 HGGEVNSSAFSP-DGQMLLTGSEDGCV--YGWETRSGQLLWRLGG-----------HTGP 65
Query: 102 VETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFN-FEETVYSHHMSPVSTKHCLVA 160
V+ ++ P D +F S+S D T+++WD + V + +V + SP S + +A
Sbjct: 66 VKFCRFSP-DGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQ---LA 121
Query: 161 VGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRAS 220
G +V L D++SG +L GHR I + +SP + LAT S DS V +WD+R +
Sbjct: 122 SGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVN-CLATGSWDSTVHIWDLRMVT 180
Query: 221 GCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENT 280
+ QA+E H+ ++ LC+++ GL L + D + +W +
Sbjct: 181 PAV---------SHQALE----GHSANISCLCYSASGL-LASGSWDKTIHIWKPTTSSLL 226
Query: 281 LVNYGKVCNNSKKGLKFTVSCGCSSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCC 340
+ G V K + F+ Y + V+ +G+ + LKG C
Sbjct: 227 IQLKGHV--TWVKSIAFSPD---ELWLASAGYSRMVKVWDCNTGKCLETLKGVLDVAHTC 281
Query: 341 VFQSNFQELYSGSRD 355
F + + L SG+ D
Sbjct: 282 AFTPDGKILVSGAAD 296
Score = 50.1 bits (118), Expect = 4e-06
Identities = 36/125 (28%), Positives = 57/125 (45%), Gaps = 19/125 (15%)
Query: 244 HNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYG------KVCNNSKKGLKF 297
H G+VN F+ DG LLT D + W + +G+ L G K C S G F
Sbjct: 20 HGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQ-LLWRLGGHTGPVKFCRFSPDGHLF 78
Query: 298 -TVSCGCSSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDC 356
+ SC C T+ ++ V + + +LKGH ++V+ F + ++L SG D
Sbjct: 79 ASASCDC-----------TVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDK 127
Query: 357 NILAW 361
++ W
Sbjct: 128 RVMLW 132
>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
sapiens]
Length = 589
Score = 75.5 bits (184), Expect = 8e-14
Identities = 65/254 (25%), Positives = 108/254 (42%), Gaps = 49/254 (19%)
Query: 117 SSSFDKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCL------VAVGTRGPKVQL 170
S S D+TLKVW+ T + T+Y H ST C+ V G+R +++
Sbjct: 318 SGSTDRTLKVWNAETGECI------HTLYGH----TSTVRCMHLHEKRVVSGSRDATLRV 367
Query: 171 CDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHN 230
D+++G C H+L GH + V + R + + + D VK+WD + CL TL
Sbjct: 368 WDIETGQCLHVLMGHVAAVRCVQYDGRR---VVSGAYDFMVKVWDPETET-CLHTLQ--- 420
Query: 231 GKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNN 290
H +V L F DG+H+++ D +R+W+ G G
Sbjct: 421 ------------GHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLT 466
Query: 291 SKKGLKFTVSCGCSSEFVFVPYGSTIAVYTVYSGEQITMLKG---HYKTVDCCVFQSNFQ 347
S LK + +++ ST+ ++ + +G+ + L+G H V C F NF
Sbjct: 467 SGMELKDNILVSGNAD-------STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNF- 518
Query: 348 ELYSGSRDCNILAW 361
+ + S D + W
Sbjct: 519 -VITSSDDGTVKLW 531
Score = 50.1 bits (118), Expect = 4e-06
Identities = 49/198 (24%), Positives = 85/198 (42%), Gaps = 27/198 (13%)
Query: 22 ESTRRVLGLELNKDRDVERIHGGGINTLDIEPVEGRYMLSGGSDGVIVLYDLENSSRQSY 81
++T RV +E + V H + + + GR ++SG D ++ ++D E +
Sbjct: 362 DATLRVWDIETGQCLHVLMGHVAAVRCVQYD---GRRVVSGAYDFMVKVWDPETET--CL 416
Query: 82 YTCKAVCSIGRDHPDVHRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFE 141
+T + H V ++Q+ D S S D +++VWD T N
Sbjct: 417 HTLQG-----------HTNRVYSLQF---DGIHVVSGSLDTSIRVWDVET------GNCI 456
Query: 142 ETVYSHHM--SPVSTKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYD 199
T+ H S + K ++ G V++ D+K+G C LQG + AV+
Sbjct: 457 HTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNK 516
Query: 200 YILATASADSRVKLWDVR 217
+ T+S D VKLWD++
Sbjct: 517 NFVITSSDDGTVKLWDLK 534
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/164 (25%), Positives = 68/164 (41%), Gaps = 31/164 (18%)
Query: 202 LATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDGLHLL 261
+ + S D+ +K+W CL TL H G V S+ N ++G
Sbjct: 276 IVSGSDDNTLKVWSAVTGK-CLRTLVGHTG----GVWSSQMRDNIIISG----------- 319
Query: 262 TVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKFTVSCGCSSE--FVFVPYGSTIAVY 319
TD +++WN+ GE C ++ G TV C E V +T+ V+
Sbjct: 320 --STDRTLKVWNAETGE---------CIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVW 368
Query: 320 TVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILAWVP 363
+ +G+ + +L GH V C Q + + + SG+ D + W P
Sbjct: 369 DIETGQCLHVLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDP 410
>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
sapiens]
Length = 707
Score = 75.5 bits (184), Expect = 8e-14
Identities = 65/254 (25%), Positives = 108/254 (42%), Gaps = 49/254 (19%)
Query: 117 SSSFDKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCL------VAVGTRGPKVQL 170
S S D+TLKVW+ T + T+Y H ST C+ V G+R +++
Sbjct: 436 SGSTDRTLKVWNAETGECI------HTLYGH----TSTVRCMHLHEKRVVSGSRDATLRV 485
Query: 171 CDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHN 230
D+++G C H+L GH + V + R + + + D VK+WD + CL TL
Sbjct: 486 WDIETGQCLHVLMGHVAAVRCVQYDGRR---VVSGAYDFMVKVWDPETET-CLHTLQ--- 538
Query: 231 GKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNN 290
H +V L F DG+H+++ D +R+W+ G G
Sbjct: 539 ------------GHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLT 584
Query: 291 SKKGLKFTVSCGCSSEFVFVPYGSTIAVYTVYSGEQITMLKG---HYKTVDCCVFQSNFQ 347
S LK + +++ ST+ ++ + +G+ + L+G H V C F NF
Sbjct: 585 SGMELKDNILVSGNAD-------STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNF- 636
Query: 348 ELYSGSRDCNILAW 361
+ + S D + W
Sbjct: 637 -VITSSDDGTVKLW 649
Score = 50.1 bits (118), Expect = 4e-06
Identities = 49/198 (24%), Positives = 85/198 (42%), Gaps = 27/198 (13%)
Query: 22 ESTRRVLGLELNKDRDVERIHGGGINTLDIEPVEGRYMLSGGSDGVIVLYDLENSSRQSY 81
++T RV +E + V H + + + GR ++SG D ++ ++D E +
Sbjct: 480 DATLRVWDIETGQCLHVLMGHVAAVRCVQYD---GRRVVSGAYDFMVKVWDPETET--CL 534
Query: 82 YTCKAVCSIGRDHPDVHRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFE 141
+T + H V ++Q+ D S S D +++VWD T N
Sbjct: 535 HTLQG-----------HTNRVYSLQF---DGIHVVSGSLDTSIRVWDVET------GNCI 574
Query: 142 ETVYSHHM--SPVSTKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYD 199
T+ H S + K ++ G V++ D+K+G C LQG + AV+
Sbjct: 575 HTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNK 634
Query: 200 YILATASADSRVKLWDVR 217
+ T+S D VKLWD++
Sbjct: 635 NFVITSSDDGTVKLWDLK 652
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/164 (25%), Positives = 68/164 (41%), Gaps = 31/164 (18%)
Query: 202 LATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDGLHLL 261
+ + S D+ +K+W CL TL H G V S+ N ++G
Sbjct: 394 IVSGSDDNTLKVWSAVTGK-CLRTLVGHTG----GVWSSQMRDNIIISG----------- 437
Query: 262 TVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKFTVSCGCSSE--FVFVPYGSTIAVY 319
TD +++WN+ GE C ++ G TV C E V +T+ V+
Sbjct: 438 --STDRTLKVWNAETGE---------CIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVW 486
Query: 320 TVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILAWVP 363
+ +G+ + +L GH V C Q + + + SG+ D + W P
Sbjct: 487 DIETGQCLHVLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDP 528
>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
sapiens]
Length = 627
Score = 75.5 bits (184), Expect = 8e-14
Identities = 65/254 (25%), Positives = 108/254 (42%), Gaps = 49/254 (19%)
Query: 117 SSSFDKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCL------VAVGTRGPKVQL 170
S S D+TLKVW+ T + T+Y H ST C+ V G+R +++
Sbjct: 356 SGSTDRTLKVWNAETGECI------HTLYGH----TSTVRCMHLHEKRVVSGSRDATLRV 405
Query: 171 CDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHN 230
D+++G C H+L GH + V + R + + + D VK+WD + CL TL
Sbjct: 406 WDIETGQCLHVLMGHVAAVRCVQYDGRR---VVSGAYDFMVKVWDPETET-CLHTLQ--- 458
Query: 231 GKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNN 290
H +V L F DG+H+++ D +R+W+ G G
Sbjct: 459 ------------GHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLT 504
Query: 291 SKKGLKFTVSCGCSSEFVFVPYGSTIAVYTVYSGEQITMLKG---HYKTVDCCVFQSNFQ 347
S LK + +++ ST+ ++ + +G+ + L+G H V C F NF
Sbjct: 505 SGMELKDNILVSGNAD-------STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNF- 556
Query: 348 ELYSGSRDCNILAW 361
+ + S D + W
Sbjct: 557 -VITSSDDGTVKLW 569
Score = 50.1 bits (118), Expect = 4e-06
Identities = 49/198 (24%), Positives = 85/198 (42%), Gaps = 27/198 (13%)
Query: 22 ESTRRVLGLELNKDRDVERIHGGGINTLDIEPVEGRYMLSGGSDGVIVLYDLENSSRQSY 81
++T RV +E + V H + + + GR ++SG D ++ ++D E +
Sbjct: 400 DATLRVWDIETGQCLHVLMGHVAAVRCVQYD---GRRVVSGAYDFMVKVWDPETET--CL 454
Query: 82 YTCKAVCSIGRDHPDVHRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFE 141
+T + H V ++Q+ D S S D +++VWD T N
Sbjct: 455 HTLQG-----------HTNRVYSLQF---DGIHVVSGSLDTSIRVWDVET------GNCI 494
Query: 142 ETVYSHHM--SPVSTKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYD 199
T+ H S + K ++ G V++ D+K+G C LQG + AV+
Sbjct: 495 HTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNK 554
Query: 200 YILATASADSRVKLWDVR 217
+ T+S D VKLWD++
Sbjct: 555 NFVITSSDDGTVKLWDLK 572
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/164 (25%), Positives = 68/164 (41%), Gaps = 31/164 (18%)
Query: 202 LATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDGLHLL 261
+ + S D+ +K+W CL TL H G V S+ N ++G
Sbjct: 314 IVSGSDDNTLKVWSAVTGK-CLRTLVGHTG----GVWSSQMRDNIIISG----------- 357
Query: 262 TVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKFTVSCGCSSE--FVFVPYGSTIAVY 319
TD +++WN+ GE C ++ G TV C E V +T+ V+
Sbjct: 358 --STDRTLKVWNAETGE---------CIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVW 406
Query: 320 TVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILAWVP 363
+ +G+ + +L GH V C Q + + + SG+ D + W P
Sbjct: 407 DIETGQCLHVLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDP 448
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 72.4 bits (176), Expect = 7e-13
Identities = 70/279 (25%), Positives = 116/279 (41%), Gaps = 58/279 (20%)
Query: 15 PLRLRRAESTRRVLGLELNKDRDVERI--------------HGGGINTLDIEPVEGRYML 60
P +LR + + ++ D +ERI H G + P + Y+L
Sbjct: 501 PKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSP-DRNYLL 559
Query: 61 SGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYSVETVQWYPHDTGMFTSSSF 120
S DG + L+ L+ + C +G H Y V Q+ P+ F S
Sbjct: 560 SSSEDGTVRLWSLQTFT----------CLVGYKG---HNYPVWDTQFSPYGY-YFVSGGH 605
Query: 121 DKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHC-----LVAVGTRGPKVQLCDLKS 175
D+ ++W T+ Q +F + H++ V+ VA G+ V+L D+ +
Sbjct: 606 DRVARLWATDHYQPLRIF-------AGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN 658
Query: 176 GSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQ 235
G+C I GH+ I ++++SP + LAT + D RV LWD+ G + + + G
Sbjct: 659 GNCVRIFTGHKGPIHSLTFSPNGRF-LATGATDGRVLLWDI----GHGLMVGELKG---- 709
Query: 236 AVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNS 274
H V L F+ DG L + DN +RLW++
Sbjct: 710 --------HTDTVCSLRFSRDGEILASGSMDNTVRLWDA 740
Score = 50.8 bits (120), Expect = 2e-06
Identities = 49/197 (24%), Positives = 86/197 (43%), Gaps = 30/197 (15%)
Query: 169 QLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQ 228
++ D K+ S IL GH + S+SP +Y+L++ S D V+LW ++ + CL+
Sbjct: 526 RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSS-SEDGTVRLWSLQTFT-CLV---- 579
Query: 229 HNGKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVC 288
G K HN V F+ G + ++ G D RLW + + + + G +
Sbjct: 580 --GYKG---------HNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLA 628
Query: 289 NNSKKGLKFTVSCG-CSSEFVFVPYGS---TIAVYTVYSGEQITMLKGHYKTVDCCVFQS 344
+ V+C +V GS T+ ++ V +G + + GH + F
Sbjct: 629 D---------VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSP 679
Query: 345 NFQELYSGSRDCNILAW 361
N + L +G+ D +L W
Sbjct: 680 NGRFLATGATDGRVLLW 696
Score = 42.7 bits (99), Expect = 6e-04
Identities = 44/185 (23%), Positives = 71/185 (38%), Gaps = 38/185 (20%)
Query: 201 ILATASADSRVKLWDVR-------RASGCLITLDQHNGKKSQAVESANTA--------HN 245
++A ADS V++W V + + L +D+ + + + TA H+
Sbjct: 484 LIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHS 543
Query: 246 GKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKFTVSCGCSS 305
G V G F+ D +LL+ D +RLW S LV Y KG + V
Sbjct: 544 GPVYGASFSPDRNYLLSSSEDGTVRLW-SLQTFTCLVGY--------KGHNYPV-----W 589
Query: 306 EFVFVPYG---------STIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDC 356
+ F PYG ++ + + + GH V+C F N + +GS D
Sbjct: 590 DTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADR 649
Query: 357 NILAW 361
+ W
Sbjct: 650 TVRLW 654
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 70.9 bits (172), Expect = 2e-12
Identities = 66/249 (26%), Positives = 112/249 (44%), Gaps = 39/249 (15%)
Query: 98 HRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVF-NFEETVYSHHMSPVSTKH 156
H+ + V W D+ + S+S DKTLK+WD ++ + V+ + +P S
Sbjct: 86 HKLGISDVAW-SSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSN-- 142
Query: 157 CLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDV 216
L+ G+ V++ D+K+G C L H + AV ++ R ++ ++S D ++WD
Sbjct: 143 -LIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFN-RDGSLIVSSSYDGLCRIWDT 200
Query: 217 RRASG-CLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSS 275
ASG CL TL + N V+ + F+ +G ++L DN ++LW+ S
Sbjct: 201 --ASGQCLKTLIDDD--------------NPPVSFVKFSPNGKYILAATLDNTLKLWDYS 244
Query: 276 NGENTLVNYG----KVC---NNSKKGLKFTVSCGCSSEFVFVPYGSTIAVYTVYSGEQIT 328
G+ G K C N S G K+ VS G V+ ++ + + E +
Sbjct: 245 KGKCLKTYTGHKNEKYCIFANFSVTGGKWIVS-GSEDNLVY--------IWNLQTKEIVQ 295
Query: 329 MLKGHYKTV 337
L+GH V
Sbjct: 296 KLQGHTDVV 304
Score = 69.7 bits (169), Expect = 4e-12
Identities = 67/282 (23%), Positives = 124/282 (43%), Gaps = 57/282 (20%)
Query: 98 HRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYSHHMS----PVS 153
H +V +V++ P+ + SSS DK +K+W A FE+T+ H + S
Sbjct: 44 HTKAVSSVKFSPNGEWL-ASSSADKLIKIWG------AYDGKFEKTISGHKLGISDVAWS 96
Query: 154 TKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKL 213
+ L+ + +++ D+ SG C L+GH + +++P+ + ++ + S D V++
Sbjct: 97 SDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSN-LIVSGSFDESVRI 155
Query: 214 WDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWN 273
WDV+ CL TL AH+ V+ + F DG +++ D R+W+
Sbjct: 156 WDVKTGK-CLKTL---------------PAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWD 199
Query: 274 SSNG---------ENTLVNYGKVCNNSKKGLKFTVSCGCSSEFVFVPYGSTIAVYTVYSG 324
+++G +N V++ K N K L T+ +T+ ++ G
Sbjct: 200 TASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLD-------------NTLKLWDYSKG 246
Query: 325 EQITMLKGHYKTVDCCVFQSNF-----QELYSGSRDCNILAW 361
+ + GH K C+F +NF + + SGS D + W
Sbjct: 247 KCLKTYTGH-KNEKYCIF-ANFSVTGGKWIVSGSEDNLVYIW 286
Score = 50.8 bits (120), Expect = 2e-06
Identities = 32/130 (24%), Positives = 58/130 (44%), Gaps = 5/130 (3%)
Query: 232 KKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNS 291
K + A++ H V+ + F+ +G L + D +++W + +G+ + K +
Sbjct: 32 KPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGK-----FEKTISGH 86
Query: 292 KKGLKFTVSCGCSSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYS 351
K G+ S+ V T+ ++ V SG+ + LKGH V CC F + S
Sbjct: 87 KLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVS 146
Query: 352 GSRDCNILAW 361
GS D ++ W
Sbjct: 147 GSFDESVRIW 156
Score = 47.0 bits (110), Expect = 3e-05
Identities = 42/185 (22%), Positives = 80/185 (43%), Gaps = 32/185 (17%)
Query: 182 LQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESAN 241
L GH + + +V +SP ++ LA++SAD +K+W ++GK E
Sbjct: 41 LAGHTKAVSSVKFSPNGEW-LASSSADKLIKIWGA------------YDGK----FEKTI 83
Query: 242 TAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKFTVSC 301
+ H ++ + ++SD L++ D +++W+ S+G+ C + KG V C
Sbjct: 84 SGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGK---------CLKTLKGHSNYVFC 134
Query: 302 GC-----SSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDC 356
C S+ V + ++ ++ V +G+ + L H V F + + S S D
Sbjct: 135 -CNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDG 193
Query: 357 NILAW 361
W
Sbjct: 194 LCRIW 198
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 70.9 bits (172), Expect = 2e-12
Identities = 66/249 (26%), Positives = 112/249 (44%), Gaps = 39/249 (15%)
Query: 98 HRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVF-NFEETVYSHHMSPVSTKH 156
H+ + V W D+ + S+S DKTLK+WD ++ + V+ + +P S
Sbjct: 86 HKLGISDVAW-SSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSN-- 142
Query: 157 CLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDV 216
L+ G+ V++ D+K+G C L H + AV ++ R ++ ++S D ++WD
Sbjct: 143 -LIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFN-RDGSLIVSSSYDGLCRIWDT 200
Query: 217 RRASG-CLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSS 275
ASG CL TL + N V+ + F+ +G ++L DN ++LW+ S
Sbjct: 201 --ASGQCLKTLIDDD--------------NPPVSFVKFSPNGKYILAATLDNTLKLWDYS 244
Query: 276 NGENTLVNYG----KVC---NNSKKGLKFTVSCGCSSEFVFVPYGSTIAVYTVYSGEQIT 328
G+ G K C N S G K+ VS G V+ ++ + + E +
Sbjct: 245 KGKCLKTYTGHKNEKYCIFANFSVTGGKWIVS-GSEDNLVY--------IWNLQTKEIVQ 295
Query: 329 MLKGHYKTV 337
L+GH V
Sbjct: 296 KLQGHTDVV 304
Score = 69.7 bits (169), Expect = 4e-12
Identities = 67/282 (23%), Positives = 124/282 (43%), Gaps = 57/282 (20%)
Query: 98 HRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYSHHMS----PVS 153
H +V +V++ P+ + SSS DK +K+W A FE+T+ H + S
Sbjct: 44 HTKAVSSVKFSPNGEWL-ASSSADKLIKIWG------AYDGKFEKTISGHKLGISDVAWS 96
Query: 154 TKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKL 213
+ L+ + +++ D+ SG C L+GH + +++P+ + ++ + S D V++
Sbjct: 97 SDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSN-LIVSGSFDESVRI 155
Query: 214 WDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWN 273
WDV+ CL TL AH+ V+ + F DG +++ D R+W+
Sbjct: 156 WDVKTGK-CLKTL---------------PAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWD 199
Query: 274 SSNG---------ENTLVNYGKVCNNSKKGLKFTVSCGCSSEFVFVPYGSTIAVYTVYSG 324
+++G +N V++ K N K L T+ +T+ ++ G
Sbjct: 200 TASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLD-------------NTLKLWDYSKG 246
Query: 325 EQITMLKGHYKTVDCCVFQSNF-----QELYSGSRDCNILAW 361
+ + GH K C+F +NF + + SGS D + W
Sbjct: 247 KCLKTYTGH-KNEKYCIF-ANFSVTGGKWIVSGSEDNLVYIW 286
Score = 50.8 bits (120), Expect = 2e-06
Identities = 32/130 (24%), Positives = 58/130 (44%), Gaps = 5/130 (3%)
Query: 232 KKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNS 291
K + A++ H V+ + F+ +G L + D +++W + +G+ + K +
Sbjct: 32 KPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGK-----FEKTISGH 86
Query: 292 KKGLKFTVSCGCSSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYS 351
K G+ S+ V T+ ++ V SG+ + LKGH V CC F + S
Sbjct: 87 KLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVS 146
Query: 352 GSRDCNILAW 361
GS D ++ W
Sbjct: 147 GSFDESVRIW 156
Score = 47.0 bits (110), Expect = 3e-05
Identities = 42/185 (22%), Positives = 80/185 (43%), Gaps = 32/185 (17%)
Query: 182 LQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESAN 241
L GH + + +V +SP ++ LA++SAD +K+W ++GK E
Sbjct: 41 LAGHTKAVSSVKFSPNGEW-LASSSADKLIKIWGA------------YDGK----FEKTI 83
Query: 242 TAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKFTVSC 301
+ H ++ + ++SD L++ D +++W+ S+G+ C + KG V C
Sbjct: 84 SGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGK---------CLKTLKGHSNYVFC 134
Query: 302 GC-----SSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDC 356
C S+ V + ++ ++ V +G+ + L H V F + + S S D
Sbjct: 135 -CNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDG 193
Query: 357 NILAW 361
W
Sbjct: 194 LCRIW 198
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 69.3 bits (168), Expect = 6e-12
Identities = 50/221 (22%), Positives = 98/221 (44%), Gaps = 27/221 (12%)
Query: 115 FTSSSFDKTLKVWDTNTLQTADVFN-FEETVYSHHMS-PVSTKHCLVAVGTRGPKVQLCD 172
F + S+D+T K+WDT + + + VY+ + P K +A G+ +L
Sbjct: 107 FITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDK---IATGSFDKTCKLWS 163
Query: 173 LKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNGK 232
+++G C H +GH EI+ +S++P+ ++AT S D+ KLWD++ NG+
Sbjct: 164 VETGKCYHTFRGHTAEIVCLSFNPQ-STLVATGSMDTTAKLWDIQ------------NGE 210
Query: 233 KSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNSK 292
+ + H+ ++ L F + G ++T D+ + +W++ G + G S
Sbjct: 211 EVYTLR----GHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISS 266
Query: 293 KGLKFTVSCGCSSEFVFVPYGSTIAVYTVYSGEQITMLKGH 333
+ S + T ++ +G+ + L GH
Sbjct: 267 ASFNWDCSLILTGSM-----DKTCKLWDATNGKCVATLTGH 302
Score = 65.5 bits (158), Expect = 8e-11
Identities = 62/266 (23%), Positives = 108/266 (40%), Gaps = 52/266 (19%)
Query: 22 ESTRRVLGLELNKDRDVERIHGGGINTLDIEPVEGRYMLSGGSDGVIVLYDLENSSRQSY 81
+ T ++ +E K R H I L P + + +G D L+D++N +
Sbjct: 156 DKTCKLWSVETGKCYHTFRGHTAEIVCLSFNP-QSTLVATGSMDTTAKLWDIQNG--EEV 212
Query: 82 YTCKAVCSIGRDHPDVHRYSVETVQWYPHDTG-MFTSSSFDKTLKVWDTNTLQTADVFNF 140
YT + +S E + + +G + SFD T+ VWD +T + ++
Sbjct: 213 YTLRG-------------HSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNIL-- 257
Query: 141 EETVYSHHMSPVSTKH-----CLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWS 195
H + +S+ L+ G+ +L D +G C L GH EIL
Sbjct: 258 -----IGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEIL----D 308
Query: 196 PRYDY---ILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLC 252
+DY ++ATASAD +++ C+ L+ H G+++ +
Sbjct: 309 SCFDYTGKLIATASADGTARIFSAATRK-CIAKLE---------------GHEGEISKIS 352
Query: 253 FTSDGLHLLTVGTDNRMRLWNSSNGE 278
F G HLLT +D R+W++ G+
Sbjct: 353 FNPQGNHLLTGSSDKTARIWDAQTGQ 378
Score = 55.1 bits (131), Expect = 1e-07
Identities = 45/193 (23%), Positives = 72/193 (37%), Gaps = 21/193 (10%)
Query: 169 QLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQ 228
+L D SG + L+GHR + A++++ Y +AT S D KLW V C T
Sbjct: 117 KLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGK-CYHTF-- 173
Query: 229 HNGKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVC 288
H ++ L F + T D +LW+ NGE G
Sbjct: 174 -------------RGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGH-- 218
Query: 289 NNSKKGLKFTVSCGCSSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQE 348
+ L F S + + T+ V+ +G ++ +L GH + F +
Sbjct: 219 SAEIISLSFNTS---GDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSL 275
Query: 349 LYSGSRDCNILAW 361
+ +GS D W
Sbjct: 276 ILTGSMDKTCKLW 288
Score = 35.0 bits (79), Expect = 0.12
Identities = 40/235 (17%), Positives = 89/235 (37%), Gaps = 60/235 (25%)
Query: 22 ESTRRVLGLELNKDRDVERIHGGGINTLDIEPVEGRYMLSGGSDGVIVLYDLENSSRQSY 81
++T ++ ++ ++ R H I +L G +++G D +V++D + + +
Sbjct: 198 DTTAKLWDIQNGEEVYTLRGHSAEIISLSFN-TSGDRIITGSFDHTVVVWDADTGRKVNI 256
Query: 82 YT--CKAVCSIGRDHPDVHRYSVETVQWYPHDTGMFTSSSFDKTLKVWD-TNTLQTADVF 138
C + S + W D + + S DKT K+WD TN A +
Sbjct: 257 LIGHCAEISSA-------------SFNW---DCSLILTGSMDKTCKLWDATNGKCVATLT 300
Query: 139 NFEETVYSH------------------HMSPVSTKHCLVAV------------------- 161
++ + + +T+ C+ +
Sbjct: 301 GHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHL 360
Query: 162 --GTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLW 214
G+ ++ D ++G C +L+GH EI + +++ + + I+ T S D+ ++W
Sbjct: 361 LTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGN-IVITGSKDNTCRIW 414
Score = 32.0 bits (71), Expect = 1.0
Identities = 26/121 (21%), Positives = 47/121 (38%), Gaps = 8/121 (6%)
Query: 243 AHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGE--NTLVNYGKVCNNSKKGLKFTVS 300
AH + + G +T D +LW++++GE NTL + N + F
Sbjct: 90 AHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGH----RNVVYAIAFNNP 145
Query: 301 CGCSSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILA 360
G + + T +++V +G+ +GH + C F + +GS D
Sbjct: 146 YG--DKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKL 203
Query: 361 W 361
W
Sbjct: 204 W 204
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 68.9 bits (167), Expect = 7e-12
Identities = 62/260 (23%), Positives = 92/260 (35%), Gaps = 99/260 (38%)
Query: 55 EGRYMLSGGSDGVIVLYDLENSSRQSYYT------------------------CKAVCSI 90
+G ++LS G D +++D + + C VC +
Sbjct: 277 KGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKL 336
Query: 91 GRDHP----DVHRYSVETVQWYPHDTG-MFTSSSFDKTLKVWDTNTLQTADVFNFEETVY 145
G+D P H V ++W P TG + S S D TLK+W
Sbjct: 337 GQDRPIKTFQGHTNEVNAIKWDP--TGNLLASCSDDMTLKIWS----------------- 377
Query: 146 SHHMSPVSTKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWS--------PR 197
+K +C H LQ H +EI + WS P
Sbjct: 378 ---------------------------MKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPN 410
Query: 198 YDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDG 257
+ +LA+AS DS V+LWDV R C+ TL T H V + F+ DG
Sbjct: 411 ANLMLASASFDSTVRLWDVDRGI-CIHTL---------------TKHQEPVYSVAFSPDG 454
Query: 258 LHLLTVGTDNRMRLWNSSNG 277
+L + D + +WN+ G
Sbjct: 455 RYLASGSFDKCVHIWNTQTG 474
Score = 40.4 bits (93), Expect = 0.003
Identities = 26/94 (27%), Positives = 45/94 (47%), Gaps = 7/94 (7%)
Query: 181 ILQGHRQEILAVSWSPRYDYILATASADSRVKLWDV--RRASGCLITLDQHNGKKSQAVE 238
+L+GH E+ +W+P D +LA+ S DS ++W++ SG + +H ++
Sbjct: 164 VLRGHESEVFICAWNPVSD-LLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREG---- 218
Query: 239 SANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLW 272
+ N V L + S+G L T D R+W
Sbjct: 219 GQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIW 252
>gi|118402582 cell division cycle 20 [Homo sapiens]
Length = 499
Score = 68.6 bits (166), Expect = 1e-11
Identities = 69/293 (23%), Positives = 128/293 (43%), Gaps = 34/293 (11%)
Query: 69 VLYDLENSSRQSYYTCKAVCSIGR---DHPDVHR-YSVETVQWYPHDTGMFTSSSFDKTL 124
VLY + + S TC+ + S+ D P++ Y + V W +G + + D ++
Sbjct: 150 VLYSQKATPGSSRKTCRYIPSLPDRILDAPEIRNDYYLNLVDW---SSGNVLAVALDNSV 206
Query: 125 KVWDTNTLQTADVFNFEETVYSHHMSPVS--TKHCLVAVGTRGPKVQLCDLKSGSCSHIL 182
+W ++ + E+ ++S V+ + +AVGT +VQL D++ +
Sbjct: 207 YLWSASSGDILQLLQMEQP--GEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNM 264
Query: 183 QGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANT 242
H + ++SW+ YIL++ S + DVR A + TL +
Sbjct: 265 TSHSARVGSLSWN---SYILSSGSRSGHIHHHDVRVAEHHVATL---------------S 306
Query: 243 AHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKFTVSCG 302
H+ +V GL + DG HL + G DN + +W S+ GE V + + +K C
Sbjct: 307 GHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPL-QTFTQHQGAVKAVAWCP 365
Query: 303 CSSEFVFVPYGST---IAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYSG 352
S + G++ I ++ V SG ++ + H V ++ +++EL SG
Sbjct: 366 WQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAH-SQVCSILWSPHYKELISG 417
Score = 39.7 bits (91), Expect = 0.005
Identities = 49/254 (19%), Positives = 86/254 (33%), Gaps = 56/254 (22%)
Query: 55 EGRYMLSGGSDGVIVLYDLENSSRQSYYTCKA-----------VCSIGRDHPDVHRYSVE 103
EG Y+ G S + L+D++ R T + + S G +H + V
Sbjct: 237 EGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSRSGHIHHHDVR 296
Query: 104 TVQ-----------------WYPHDTGMFTSSSFDKTLKVWDTNT-------LQTADVFN 139
+ W P D S D + VW + LQT
Sbjct: 297 VAEHHVATLSGHSQEVCGLRWAP-DGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFT--Q 353
Query: 140 FEETVYSHHMSPVSTKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRY- 198
+ V + P + GT +++ ++ SG+C + H Q + ++ WSP Y
Sbjct: 354 HQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQ-VCSILWSPHYK 412
Query: 199 DYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDGL 258
+ I A +++ +W + A + H +V L + DG
Sbjct: 413 ELISGHGFAQNQLVIWKY----------------PTMAKVAELKGHTSRVLSLTMSPDGA 456
Query: 259 HLLTVGTDNRMRLW 272
+ + D +RLW
Sbjct: 457 TVASAAADETLRLW 470
>gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo
sapiens]
Length = 522
Score = 68.2 bits (165), Expect = 1e-11
Identities = 63/255 (24%), Positives = 111/255 (43%), Gaps = 49/255 (19%)
Query: 47 NTLDIEPVEGRYMLSGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYSVETVQ 106
+T+ ++P + + S +DG + L+ L++ + V I + H V V
Sbjct: 285 STVSLDPKDVN-LASCAADGSVKLWSLDSD--------EPVADI-----EGHTVRVARVM 330
Query: 107 WYPHDTGMFTSSS-FDKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCLVAVGTRG 165
W+P +G F ++ +D++ ++WD + ++ + E + L G
Sbjct: 331 WHP--SGRFLGTTCYDRSWRLWDLEAQE--EILHQEGHSMGVYDIAFHQDGSLAGTGGLD 386
Query: 166 PKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLIT 225
++ DL++G C L+GH +EI +++SP Y +AT S D+ K+WD+R+ C+ T
Sbjct: 387 AFGRVWDLRTGRCIMFLEGHLKEIYGINFSPN-GYHIATGSGDNTCKVWDLRQRR-CVYT 444
Query: 226 LDQH----NGKKSQAVES--------ANTA----------------HNGKVNGLCFTSDG 257
+ H G K + + NTA H GKV GL +SDG
Sbjct: 445 IPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDG 504
Query: 258 LHLLTVGTDNRMRLW 272
+ T D +LW
Sbjct: 505 QLIATCSYDRTFKLW 519
Score = 33.5 bits (75), Expect = 0.34
Identities = 59/281 (20%), Positives = 94/281 (33%), Gaps = 37/281 (13%)
Query: 114 MFTSSSFDKTLKVW---DTNTLQTADVFNFEE-TVYSHHMSPVST--KHCLVAVGTRGPK 167
M ++ + K+W D N L T N + H S VS K +A
Sbjct: 245 MLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGS 304
Query: 168 VQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLD 227
V+L L S ++GH + V W P + L T D +LWD+ L
Sbjct: 305 VKLWSLDSDEPVADIEGHTVRVARVMWHPSGRF-LGTTCYDRSWRLWDLEAQEEILHQEG 363
Query: 228 QHNGKKSQAVESANT--------------------------AHNGKVNGLCFTSDGLHLL 261
G A + H ++ G+ F+ +G H+
Sbjct: 364 HSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIA 423
Query: 262 TVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKFTVSCGCSSEFVFVPYGSTIAVYTV 321
T DN ++W+ + V N G+KF G + + Y +T ++T
Sbjct: 424 TGSGDNTCKVWDLR--QRRCVYTIPAHQNLVTGVKFEPIHG--NFLLTGAYDNTAKIWTH 479
Query: 322 YSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILAWV 362
+ L GH V S+ Q + + S D W+
Sbjct: 480 PGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWM 520
>gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]
Length = 425
Score = 67.8 bits (164), Expect = 2e-11
Identities = 51/219 (23%), Positives = 95/219 (43%), Gaps = 12/219 (5%)
Query: 58 YMLSGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYSVETVQWYPHDTGMFTS 117
++LS D + L+D+ ++ G H VE V W+ +F S
Sbjct: 191 HLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTG------HSAVVEDVAWHLLHESLFGS 244
Query: 118 SSFDKTLKVWDTNTLQTADVFNFEE--TVYSHHMSPVSTKHCLVAVGTRGPKVQLCDLKS 175
+ D+ L +WDT + T+ + + T + +S ++A G+ V L DL++
Sbjct: 245 VADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN 304
Query: 176 GSCS-HILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNGKKS 234
H + H+ EI V WSP + ILA++ D R+ +WD+ + D +G
Sbjct: 305 LKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPE 364
Query: 235 QAVESANTAHNGKVNGLCFT-SDGLHLLTVGTDNRMRLW 272
+ + H K++ + ++ + +V DN M++W
Sbjct: 365 --LLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIW 401
Score = 63.5 bits (153), Expect = 3e-10
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 27/198 (13%)
Query: 91 GRDHPDV----HRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYS 146
G +PD+ H+ + W + +G S+S D T+ +WD N + +++
Sbjct: 164 GECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFT 223
Query: 147 HHMSPVST------KHCLVAVGTRGPKVQLCDLKSGSCS---HILQGHRQEILAVSWSPR 197
H + V L K+ + D +S + S H++ H E+ +S++P
Sbjct: 224 GHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPY 283
Query: 198 YDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDG 257
++ILAT SAD V LWD+R L T + H K + + + HN +
Sbjct: 284 SEFILATGSADKTVALWDLRNLKLKLHTFESH---KDEIFQVHWSPHNETI--------- 331
Query: 258 LHLLTVGTDNRMRLWNSS 275
L + GTD R+ +W+ S
Sbjct: 332 --LASSGTDRRLNVWDLS 347
Score = 46.6 bits (109), Expect = 4e-05
Identities = 36/175 (20%), Positives = 63/175 (36%), Gaps = 42/175 (24%)
Query: 42 HGGGINTLDIEPVEGRYMLSGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYS 101
H +N L P + +G +D + L+DL N + + + H+
Sbjct: 271 HTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTF------------ESHKDE 318
Query: 102 VETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCLVAV 161
+ V W PH+ + SS D+ L VWD + + E
Sbjct: 319 IFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAED------------------ 360
Query: 162 GTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDV 216
GP L I GH +I SW+P +++ + S D+ +++W +
Sbjct: 361 ---GPPELL---------FIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQM 403
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 67.4 bits (163), Expect = 2e-11
Identities = 62/260 (23%), Positives = 91/260 (35%), Gaps = 99/260 (38%)
Query: 55 EGRYMLSGGSDGVIVLYDLENSSRQSYYT------------------------CKAVCSI 90
+G Y+LS G D +++D + + C VC +
Sbjct: 287 KGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCIHVCRL 346
Query: 91 GRDHP----DVHRYSVETVQWYPHDTGMFTSS-SFDKTLKVWDTNTLQTADVFNFEETVY 145
G DHP H V ++W P +GM +S S D TLK+W
Sbjct: 347 GCDHPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWS----------------- 387
Query: 146 SHHMSPVSTKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWS--------PR 197
+K +C H LQ H +EI + WS P
Sbjct: 388 ---------------------------MKQDACVHDLQAHSKEIYTIKWSPTGPATSNPN 420
Query: 198 YDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDG 257
+LA+AS DS V+LWDV + C TL H V + F+ DG
Sbjct: 421 SSIMLASASFDSTVRLWDVEQGV-CTHTL---------------MKHQEPVYSVAFSPDG 464
Query: 258 LHLLTVGTDNRMRLWNSSNG 277
+L + D + +WN+ +G
Sbjct: 465 KYLASGSFDKYVHIWNTQSG 484
Score = 43.5 bits (101), Expect = 3e-04
Identities = 30/137 (21%), Positives = 54/137 (39%), Gaps = 40/137 (29%)
Query: 181 ILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRAS-------------------- 220
+L+GH E+ +W+P D +LA+ S DS ++W++ S
Sbjct: 174 VLRGHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 232
Query: 221 --------------GCLITLDQHNGKKSQAVESANTA-----HNGKVNGLCFTSDGLHLL 261
G L+ + ++G E+ N A H G + L + G ++L
Sbjct: 233 PSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKKGNYVL 292
Query: 262 TVGTDNRMRLWNSSNGE 278
+ G D +W++ GE
Sbjct: 293 SAGVDKTTIIWDAHTGE 309
Score = 34.3 bits (77), Expect = 0.20
Identities = 40/217 (18%), Positives = 78/217 (35%), Gaps = 30/217 (13%)
Query: 174 KSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRA---------SGCLI 224
++G+ + L H+ I A+ W+ + +Y+L+ A D +WD S +
Sbjct: 264 ENGNLASTLGQHKGPIFALKWNKKGNYVLS-AGVDKTTIIWDAHTGEAKQQFPFHSAPAL 322
Query: 225 TLDQHNGKKSQAVES----------------ANTAHNGKVNGLCFTSDGLHLLTVGTDNR 268
+D N + + H +VN + + G+ L + D
Sbjct: 323 DVDWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMT 382
Query: 269 MRLWNSSNGE--NTLVNYGKVCNNSKKGLKFTVSCGCSSEFVFVP--YGSTIAVYTVYSG 324
+++W+ + L + K K + +S + + ST+ ++ V G
Sbjct: 383 LKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQG 442
Query: 325 EQITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILAW 361
L H + V F + + L SGS D + W
Sbjct: 443 VCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIW 479
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 67.4 bits (163), Expect = 2e-11
Identities = 62/260 (23%), Positives = 91/260 (35%), Gaps = 99/260 (38%)
Query: 55 EGRYMLSGGSDGVIVLYDLENSSRQSYYT------------------------CKAVCSI 90
+G Y+LS G D +++D + + C VC +
Sbjct: 287 KGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCIHVCRL 346
Query: 91 GRDHP----DVHRYSVETVQWYPHDTGMFTSS-SFDKTLKVWDTNTLQTADVFNFEETVY 145
G DHP H V ++W P +GM +S S D TLK+W
Sbjct: 347 GCDHPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWS----------------- 387
Query: 146 SHHMSPVSTKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWS--------PR 197
+K +C H LQ H +EI + WS P
Sbjct: 388 ---------------------------MKQDACVHDLQAHSKEIYTIKWSPTGPATSNPN 420
Query: 198 YDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDG 257
+LA+AS DS V+LWDV + C TL H V + F+ DG
Sbjct: 421 SSIMLASASFDSTVRLWDVEQGV-CTHTL---------------MKHQEPVYSVAFSPDG 464
Query: 258 LHLLTVGTDNRMRLWNSSNG 277
+L + D + +WN+ +G
Sbjct: 465 KYLASGSFDKYVHIWNTQSG 484
Score = 43.5 bits (101), Expect = 3e-04
Identities = 30/137 (21%), Positives = 54/137 (39%), Gaps = 40/137 (29%)
Query: 181 ILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRAS-------------------- 220
+L+GH E+ +W+P D +LA+ S DS ++W++ S
Sbjct: 174 VLRGHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 232
Query: 221 --------------GCLITLDQHNGKKSQAVESANTA-----HNGKVNGLCFTSDGLHLL 261
G L+ + ++G E+ N A H G + L + G ++L
Sbjct: 233 PSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKKGNYVL 292
Query: 262 TVGTDNRMRLWNSSNGE 278
+ G D +W++ GE
Sbjct: 293 SAGVDKTTIIWDAHTGE 309
Score = 34.3 bits (77), Expect = 0.20
Identities = 40/217 (18%), Positives = 78/217 (35%), Gaps = 30/217 (13%)
Query: 174 KSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRA---------SGCLI 224
++G+ + L H+ I A+ W+ + +Y+L+ A D +WD S +
Sbjct: 264 ENGNLASTLGQHKGPIFALKWNKKGNYVLS-AGVDKTTIIWDAHTGEAKQQFPFHSAPAL 322
Query: 225 TLDQHNGKKSQAVES----------------ANTAHNGKVNGLCFTSDGLHLLTVGTDNR 268
+D N + + H +VN + + G+ L + D
Sbjct: 323 DVDWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMT 382
Query: 269 MRLWNSSNGE--NTLVNYGKVCNNSKKGLKFTVSCGCSSEFVFVP--YGSTIAVYTVYSG 324
+++W+ + L + K K + +S + + ST+ ++ V G
Sbjct: 383 LKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQG 442
Query: 325 EQITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILAW 361
L H + V F + + L SGS D + W
Sbjct: 443 VCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIW 479
>gi|15150805 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 67.4 bits (163), Expect = 2e-11
Identities = 62/260 (23%), Positives = 91/260 (35%), Gaps = 99/260 (38%)
Query: 55 EGRYMLSGGSDGVIVLYDLENSSRQSYYT------------------------CKAVCSI 90
+G Y+LS G D +++D + + C VC +
Sbjct: 287 KGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCIHVCRL 346
Query: 91 GRDHP----DVHRYSVETVQWYPHDTGMFTSS-SFDKTLKVWDTNTLQTADVFNFEETVY 145
G DHP H V ++W P +GM +S S D TLK+W
Sbjct: 347 GCDHPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWS----------------- 387
Query: 146 SHHMSPVSTKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWS--------PR 197
+K +C H LQ H +EI + WS P
Sbjct: 388 ---------------------------MKQDACVHDLQAHSKEIYTIKWSPTGPATSNPN 420
Query: 198 YDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDG 257
+LA+AS DS V+LWDV + C TL H V + F+ DG
Sbjct: 421 SSIMLASASFDSTVRLWDVEQGV-CTHTL---------------MKHQEPVYSVAFSPDG 464
Query: 258 LHLLTVGTDNRMRLWNSSNG 277
+L + D + +WN+ +G
Sbjct: 465 KYLASGSFDKYVHIWNTQSG 484
Score = 43.5 bits (101), Expect = 3e-04
Identities = 30/137 (21%), Positives = 54/137 (39%), Gaps = 40/137 (29%)
Query: 181 ILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRAS-------------------- 220
+L+GH E+ +W+P D +LA+ S DS ++W++ S
Sbjct: 174 VLRGHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 232
Query: 221 --------------GCLITLDQHNGKKSQAVESANTA-----HNGKVNGLCFTSDGLHLL 261
G L+ + ++G E+ N A H G + L + G ++L
Sbjct: 233 PSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKKGNYVL 292
Query: 262 TVGTDNRMRLWNSSNGE 278
+ G D +W++ GE
Sbjct: 293 SAGVDKTTIIWDAHTGE 309
Score = 34.3 bits (77), Expect = 0.20
Identities = 40/217 (18%), Positives = 78/217 (35%), Gaps = 30/217 (13%)
Query: 174 KSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRA---------SGCLI 224
++G+ + L H+ I A+ W+ + +Y+L+ A D +WD S +
Sbjct: 264 ENGNLASTLGQHKGPIFALKWNKKGNYVLS-AGVDKTTIIWDAHTGEAKQQFPFHSAPAL 322
Query: 225 TLDQHNGKKSQAVES----------------ANTAHNGKVNGLCFTSDGLHLLTVGTDNR 268
+D N + + H +VN + + G+ L + D
Sbjct: 323 DVDWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMT 382
Query: 269 MRLWNSSNGE--NTLVNYGKVCNNSKKGLKFTVSCGCSSEFVFVP--YGSTIAVYTVYSG 324
+++W+ + L + K K + +S + + ST+ ++ V G
Sbjct: 383 LKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQG 442
Query: 325 EQITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILAW 361
L H + V F + + L SGS D + W
Sbjct: 443 VCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIW 479
>gi|8923881 WD SOCS-box protein 2 [Homo sapiens]
Length = 404
Score = 67.0 bits (162), Expect = 3e-11
Identities = 50/178 (28%), Positives = 87/178 (48%), Gaps = 12/178 (6%)
Query: 98 HRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNT--LQTADVFNFEETVYSHHMSPVSTK 155
H+ V + + P + + S+S DKTL++WD N Q + + VY +SP +
Sbjct: 152 HQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSM 211
Query: 156 HCLVAVGTRGPK-VQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLW 214
C A G K V L ++S + L+GH+ +++ +SP +L TAS D+ V +W
Sbjct: 212 LCSAA----GEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPD-SALLVTASYDTNVIMW 266
Query: 215 DVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLW 272
D H+ + A++ ++ H + +CF+ +GL+L TV D +R+W
Sbjct: 267 DPYTGERLR---SLHHTQVDPAMDDSDV-HISSLRSVCFSPEGLYLATVADDRLLRIW 320
Score = 50.1 bits (118), Expect = 4e-06
Identities = 45/192 (23%), Positives = 84/192 (43%), Gaps = 31/192 (16%)
Query: 201 ILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDG-LH 259
+LAT D ++K+W+V+ L+ L+ + H V L FT G L
Sbjct: 125 VLATGLNDGQIKIWEVQTG---LLLLNL-------------SGHQDVVRDLSFTPSGSLI 168
Query: 260 LLTVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKFTVSCGCSSEFVFVPYGS---TI 316
L++ D +R+W+ L +GK L++ C S + + + ++
Sbjct: 169 LVSASRDKTLRIWD-------LNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSV 221
Query: 317 AVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILAWVPSLYEPVPDDDETT 376
++++ S I L+GH +V C F + L + S D N++ W P E + +
Sbjct: 222 FLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERL----RSL 277
Query: 377 TKSQLNPAFEDA 388
+Q++PA +D+
Sbjct: 278 HHTQVDPAMDDS 289
Score = 45.4 bits (106), Expect = 9e-05
Identities = 36/163 (22%), Positives = 67/163 (41%), Gaps = 28/163 (17%)
Query: 144 VYSHHMSPVSTKHCLV-AVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYIL 202
+++ H V CLV A G ++++ ++++G L GH+ + +S++P IL
Sbjct: 110 LWARHHPQVPDVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLIL 169
Query: 203 ATASADSRVKLWDVRRASGCLITLDQH-------------------NGKKSQAVESANT- 242
+AS D +++WD+ + + L H G+KS + S +
Sbjct: 170 VSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSY 229
Query: 243 -------AHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGE 278
H V F+ D L+T D + +W+ GE
Sbjct: 230 TLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGE 272
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 66.6 bits (161), Expect = 4e-11
Identities = 52/219 (23%), Positives = 95/219 (43%), Gaps = 12/219 (5%)
Query: 58 YMLSGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYSVETVQWYPHDTGMFTS 117
++LS D I L+D+ ++ G H VE V W+ +F S
Sbjct: 157 HLLSASDDHTICLWDISAVPKEGKVVDAKTIFTG------HTAVVEDVSWHLLHESLFGS 210
Query: 118 SSFDKTLKVWDTNTLQTADVFNFEE--TVYSHHMSPVSTKHCLVAVGTRGPKVQLCDLKS 175
+ D+ L +WDT + T+ + + T + +S ++A G+ V L DL++
Sbjct: 211 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN 270
Query: 176 GSCS-HILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNGKKS 234
H + H+ EI V WSP + ILA++ D R+ +WD+ + D +G
Sbjct: 271 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE 330
Query: 235 QAVESANTAHNGKVNGLCFT-SDGLHLLTVGTDNRMRLW 272
+ + H K++ + ++ + +V DN M++W
Sbjct: 331 --LLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVW 367
Score = 65.9 bits (159), Expect = 6e-11
Identities = 50/198 (25%), Positives = 88/198 (44%), Gaps = 27/198 (13%)
Query: 91 GRDHPDV----HRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYS 146
G +PD+ H+ + W P+ +G S+S D T+ +WD + + +T+++
Sbjct: 130 GECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFT 189
Query: 147 HHMSPVST------KHCLVAVGTRGPKVQLCDLKSGSCS---HILQGHRQEILAVSWSPR 197
H + V L K+ + D +S + S H + H E+ +S++P
Sbjct: 190 GHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPY 249
Query: 198 YDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDG 257
++ILAT SAD V LWD+R L + + H K + + + HN +
Sbjct: 250 SEFILATGSADKTVALWDLRNLKLKLHSFESH---KDEIFQVQWSPHNETI--------- 297
Query: 258 LHLLTVGTDNRMRLWNSS 275
L + GTD R+ +W+ S
Sbjct: 298 --LASSGTDRRLNVWDLS 313
Score = 50.4 bits (119), Expect = 3e-06
Identities = 38/175 (21%), Positives = 66/175 (37%), Gaps = 42/175 (24%)
Query: 42 HGGGINTLDIEPVEGRYMLSGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYS 101
H +N L P + +G +D + L+DL N + + + H+
Sbjct: 237 HTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSF------------ESHKDE 284
Query: 102 VETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCLVAV 161
+ VQW PH+ + SS D+ L VWD + + SP +
Sbjct: 285 IFQVQWSPHNETILASSGTDRRLNVWDLSKI-------------GEEQSPEDAED----- 326
Query: 162 GTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDV 216
GP L I GH +I SW+P +++ + S D+ +++W +
Sbjct: 327 ---GPPELL---------FIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQM 369
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 66.6 bits (161), Expect = 4e-11
Identities = 52/219 (23%), Positives = 95/219 (43%), Gaps = 12/219 (5%)
Query: 58 YMLSGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYSVETVQWYPHDTGMFTS 117
++LS D I L+D+ ++ G H VE V W+ +F S
Sbjct: 191 HLLSASDDHTICLWDISAVPKEGKVVDAKTIFTG------HTAVVEDVSWHLLHESLFGS 244
Query: 118 SSFDKTLKVWDTNTLQTADVFNFEE--TVYSHHMSPVSTKHCLVAVGTRGPKVQLCDLKS 175
+ D+ L +WDT + T+ + + T + +S ++A G+ V L DL++
Sbjct: 245 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN 304
Query: 176 GSCS-HILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNGKKS 234
H + H+ EI V WSP + ILA++ D R+ +WD+ + D +G
Sbjct: 305 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE 364
Query: 235 QAVESANTAHNGKVNGLCFT-SDGLHLLTVGTDNRMRLW 272
+ + H K++ + ++ + +V DN M++W
Sbjct: 365 --LLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVW 401
Score = 65.9 bits (159), Expect = 6e-11
Identities = 50/198 (25%), Positives = 88/198 (44%), Gaps = 27/198 (13%)
Query: 91 GRDHPDV----HRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYS 146
G +PD+ H+ + W P+ +G S+S D T+ +WD + + +T+++
Sbjct: 164 GECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFT 223
Query: 147 HHMSPVST------KHCLVAVGTRGPKVQLCDLKSGSCS---HILQGHRQEILAVSWSPR 197
H + V L K+ + D +S + S H + H E+ +S++P
Sbjct: 224 GHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPY 283
Query: 198 YDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDG 257
++ILAT SAD V LWD+R L + + H K + + + HN +
Sbjct: 284 SEFILATGSADKTVALWDLRNLKLKLHSFESH---KDEIFQVQWSPHNETI--------- 331
Query: 258 LHLLTVGTDNRMRLWNSS 275
L + GTD R+ +W+ S
Sbjct: 332 --LASSGTDRRLNVWDLS 347
Score = 50.4 bits (119), Expect = 3e-06
Identities = 38/175 (21%), Positives = 66/175 (37%), Gaps = 42/175 (24%)
Query: 42 HGGGINTLDIEPVEGRYMLSGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYS 101
H +N L P + +G +D + L+DL N + + + H+
Sbjct: 271 HTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSF------------ESHKDE 318
Query: 102 VETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCLVAV 161
+ VQW PH+ + SS D+ L VWD + + SP +
Sbjct: 319 IFQVQWSPHNETILASSGTDRRLNVWDLSKI-------------GEEQSPEDAED----- 360
Query: 162 GTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDV 216
GP L I GH +I SW+P +++ + S D+ +++W +
Sbjct: 361 ---GPPELL---------FIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQM 403
>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
sapiens]
Length = 425
Score = 66.6 bits (161), Expect = 4e-11
Identities = 52/219 (23%), Positives = 95/219 (43%), Gaps = 12/219 (5%)
Query: 58 YMLSGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYSVETVQWYPHDTGMFTS 117
++LS D I L+D+ ++ G H VE V W+ +F S
Sbjct: 192 HLLSASDDHTICLWDISAVPKEGKVVDAKTIFTG------HTAVVEDVSWHLLHESLFGS 245
Query: 118 SSFDKTLKVWDTNTLQTADVFNFEE--TVYSHHMSPVSTKHCLVAVGTRGPKVQLCDLKS 175
+ D+ L +WDT + T+ + + T + +S ++A G+ V L DL++
Sbjct: 246 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN 305
Query: 176 GSCS-HILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNGKKS 234
H + H+ EI V WSP + ILA++ D R+ +WD+ + D +G
Sbjct: 306 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE 365
Query: 235 QAVESANTAHNGKVNGLCFT-SDGLHLLTVGTDNRMRLW 272
+ + H K++ + ++ + +V DN M++W
Sbjct: 366 --LLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVW 402
Score = 65.9 bits (159), Expect = 6e-11
Identities = 50/198 (25%), Positives = 88/198 (44%), Gaps = 27/198 (13%)
Query: 91 GRDHPDV----HRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYS 146
G +PD+ H+ + W P+ +G S+S D T+ +WD + + +T+++
Sbjct: 165 GECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFT 224
Query: 147 HHMSPVST------KHCLVAVGTRGPKVQLCDLKSGSCS---HILQGHRQEILAVSWSPR 197
H + V L K+ + D +S + S H + H E+ +S++P
Sbjct: 225 GHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPY 284
Query: 198 YDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDG 257
++ILAT SAD V LWD+R L + + H K + + + HN +
Sbjct: 285 SEFILATGSADKTVALWDLRNLKLKLHSFESH---KDEIFQVQWSPHNETI--------- 332
Query: 258 LHLLTVGTDNRMRLWNSS 275
L + GTD R+ +W+ S
Sbjct: 333 --LASSGTDRRLNVWDLS 348
Score = 50.4 bits (119), Expect = 3e-06
Identities = 38/175 (21%), Positives = 66/175 (37%), Gaps = 42/175 (24%)
Query: 42 HGGGINTLDIEPVEGRYMLSGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYS 101
H +N L P + +G +D + L+DL N + + + H+
Sbjct: 272 HTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSF------------ESHKDE 319
Query: 102 VETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCLVAV 161
+ VQW PH+ + SS D+ L VWD + + SP +
Sbjct: 320 IFQVQWSPHNETILASSGTDRRLNVWDLSKI-------------GEEQSPEDAED----- 361
Query: 162 GTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDV 216
GP L I GH +I SW+P +++ + S D+ +++W +
Sbjct: 362 ---GPPELL---------FIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQM 404
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 66.6 bits (161), Expect = 4e-11
Identities = 62/260 (23%), Positives = 91/260 (35%), Gaps = 99/260 (38%)
Query: 55 EGRYMLSGGSDGVIVLYDLENSSRQSYYT------------------------CKAVCSI 90
+G Y+LS G D +++D + + C VC +
Sbjct: 289 KGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRL 348
Query: 91 GRDHP----DVHRYSVETVQWYPHDTGMFTSS-SFDKTLKVWDTNTLQTADVFNFEETVY 145
G D P H V ++W P +GM +S S D TLK+W
Sbjct: 349 GCDRPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWS----------------- 389
Query: 146 SHHMSPVSTKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSP--------R 197
+K C H LQ H +EI + WSP
Sbjct: 390 ---------------------------MKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPN 422
Query: 198 YDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDG 257
+ +LA+AS DS V+LWD+ R C TL T H V + F+ DG
Sbjct: 423 SNIMLASASFDSTVRLWDIERGV-CTHTL---------------TKHQEPVYSVAFSPDG 466
Query: 258 LHLLTVGTDNRMRLWNSSNG 277
+L + D + +WN+ +G
Sbjct: 467 KYLASGSFDKCVHIWNTQSG 486
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/137 (21%), Positives = 52/137 (37%), Gaps = 40/137 (29%)
Query: 181 ILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRAS-------------------- 220
+L+GH E+ +W+P D +LA+ S DS ++W++ S
Sbjct: 176 VLRGHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 234
Query: 221 --------------GCLITLDQHNGKKSQAVESANTA-----HNGKVNGLCFTSDGLHLL 261
G L+ ++G E N A H G + L + G ++L
Sbjct: 235 PSNKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYIL 294
Query: 262 TVGTDNRMRLWNSSNGE 278
+ G D +W++ GE
Sbjct: 295 SAGVDKTTIIWDAHTGE 311
Score = 35.0 bits (79), Expect = 0.12
Identities = 58/310 (18%), Positives = 109/310 (35%), Gaps = 54/310 (17%)
Query: 98 HRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYSH------HMSP 151
H V W P + + S S D T ++W+ N + V H H P
Sbjct: 180 HESEVFICAWNPV-SDLLASGSGDSTARIWNLNENSNG---GSTQLVLRHCIREGGHDVP 235
Query: 152 VS---------TKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYIL 202
+ T L+A G+ ++ + G+ + L H+ I A+ W+ + +YIL
Sbjct: 236 SNKDVTSLDWNTNGTLLATGSYDGFARIWT-EDGNLASTLGQHKGPIFALKWNRKGNYIL 294
Query: 203 ATASADSRVKLWDVRRA---------SGCLITLDQHNGKKSQAVES-------------- 239
+A D +WD S + +D N + +
Sbjct: 295 -SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRP 353
Query: 240 --ANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKF 297
H +VN + + G+ L + D +++W S + ++ + N +K+
Sbjct: 354 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIW--SMKQEVCIHDLQAHNKEIYTIKW 411
Query: 298 TVSCGCSSE------FVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYS 351
+ + +S + ST+ ++ + G L H + V F + + L S
Sbjct: 412 SPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLAS 471
Query: 352 GSRDCNILAW 361
GS D + W
Sbjct: 472 GSFDKCVHIW 481
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 66.6 bits (161), Expect = 4e-11
Identities = 62/260 (23%), Positives = 91/260 (35%), Gaps = 99/260 (38%)
Query: 55 EGRYMLSGGSDGVIVLYDLENSSRQSYYT------------------------CKAVCSI 90
+G Y+LS G D +++D + + C VC +
Sbjct: 289 KGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRL 348
Query: 91 GRDHP----DVHRYSVETVQWYPHDTGMFTSS-SFDKTLKVWDTNTLQTADVFNFEETVY 145
G D P H V ++W P +GM +S S D TLK+W
Sbjct: 349 GCDRPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWS----------------- 389
Query: 146 SHHMSPVSTKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSP--------R 197
+K C H LQ H +EI + WSP
Sbjct: 390 ---------------------------MKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPN 422
Query: 198 YDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDG 257
+ +LA+AS DS V+LWD+ R C TL T H V + F+ DG
Sbjct: 423 SNIMLASASFDSTVRLWDIERGV-CTHTL---------------TKHQEPVYSVAFSPDG 466
Query: 258 LHLLTVGTDNRMRLWNSSNG 277
+L + D + +WN+ +G
Sbjct: 467 KYLASGSFDKCVHIWNTQSG 486
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/137 (21%), Positives = 52/137 (37%), Gaps = 40/137 (29%)
Query: 181 ILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRAS-------------------- 220
+L+GH E+ +W+P D +LA+ S DS ++W++ S
Sbjct: 176 VLRGHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 234
Query: 221 --------------GCLITLDQHNGKKSQAVESANTA-----HNGKVNGLCFTSDGLHLL 261
G L+ ++G E N A H G + L + G ++L
Sbjct: 235 PSNKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYIL 294
Query: 262 TVGTDNRMRLWNSSNGE 278
+ G D +W++ GE
Sbjct: 295 SAGVDKTTIIWDAHTGE 311
Score = 35.0 bits (79), Expect = 0.12
Identities = 58/310 (18%), Positives = 109/310 (35%), Gaps = 54/310 (17%)
Query: 98 HRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYSH------HMSP 151
H V W P + + S S D T ++W+ N + V H H P
Sbjct: 180 HESEVFICAWNPV-SDLLASGSGDSTARIWNLNENSNG---GSTQLVLRHCIREGGHDVP 235
Query: 152 VS---------TKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYIL 202
+ T L+A G+ ++ + G+ + L H+ I A+ W+ + +YIL
Sbjct: 236 SNKDVTSLDWNTNGTLLATGSYDGFARIWT-EDGNLASTLGQHKGPIFALKWNRKGNYIL 294
Query: 203 ATASADSRVKLWDVRRA---------SGCLITLDQHNGKKSQAVES-------------- 239
+A D +WD S + +D N + +
Sbjct: 295 -SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRP 353
Query: 240 --ANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKF 297
H +VN + + G+ L + D +++W S + ++ + N +K+
Sbjct: 354 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIW--SMKQEVCIHDLQAHNKEIYTIKW 411
Query: 298 TVSCGCSSE------FVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYS 351
+ + +S + ST+ ++ + G L H + V F + + L S
Sbjct: 412 SPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLAS 471
Query: 352 GSRDCNILAW 361
GS D + W
Sbjct: 472 GSFDKCVHIW 481
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 66.6 bits (161), Expect = 4e-11
Identities = 62/260 (23%), Positives = 91/260 (35%), Gaps = 99/260 (38%)
Query: 55 EGRYMLSGGSDGVIVLYDLENSSRQSYYT------------------------CKAVCSI 90
+G Y+LS G D +++D + + C VC +
Sbjct: 340 KGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRL 399
Query: 91 GRDHP----DVHRYSVETVQWYPHDTGMFTSS-SFDKTLKVWDTNTLQTADVFNFEETVY 145
G D P H V ++W P +GM +S S D TLK+W
Sbjct: 400 GCDRPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWS----------------- 440
Query: 146 SHHMSPVSTKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSP--------R 197
+K C H LQ H +EI + WSP
Sbjct: 441 ---------------------------MKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPN 473
Query: 198 YDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDG 257
+ +LA+AS DS V+LWD+ R C TL T H V + F+ DG
Sbjct: 474 SNIMLASASFDSTVRLWDIERGV-CTHTL---------------TKHQEPVYSVAFSPDG 517
Query: 258 LHLLTVGTDNRMRLWNSSNG 277
+L + D + +WN+ +G
Sbjct: 518 KYLASGSFDKCVHIWNTQSG 537
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/137 (21%), Positives = 52/137 (37%), Gaps = 40/137 (29%)
Query: 181 ILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRAS-------------------- 220
+L+GH E+ +W+P D +LA+ S DS ++W++ S
Sbjct: 227 VLRGHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 285
Query: 221 --------------GCLITLDQHNGKKSQAVESANTA-----HNGKVNGLCFTSDGLHLL 261
G L+ ++G E N A H G + L + G ++L
Sbjct: 286 PSNKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYIL 345
Query: 262 TVGTDNRMRLWNSSNGE 278
+ G D +W++ GE
Sbjct: 346 SAGVDKTTIIWDAHTGE 362
Score = 35.0 bits (79), Expect = 0.12
Identities = 58/310 (18%), Positives = 109/310 (35%), Gaps = 54/310 (17%)
Query: 98 HRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYSH------HMSP 151
H V W P + + S S D T ++W+ N + V H H P
Sbjct: 231 HESEVFICAWNPV-SDLLASGSGDSTARIWNLNENSNG---GSTQLVLRHCIREGGHDVP 286
Query: 152 VS---------TKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYIL 202
+ T L+A G+ ++ + G+ + L H+ I A+ W+ + +YIL
Sbjct: 287 SNKDVTSLDWNTNGTLLATGSYDGFARIWT-EDGNLASTLGQHKGPIFALKWNRKGNYIL 345
Query: 203 ATASADSRVKLWDVRRA---------SGCLITLDQHNGKKSQAVES-------------- 239
+A D +WD S + +D N + +
Sbjct: 346 -SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRP 404
Query: 240 --ANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKF 297
H +VN + + G+ L + D +++W S + ++ + N +K+
Sbjct: 405 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIW--SMKQEVCIHDLQAHNKEIYTIKW 462
Query: 298 TVSCGCSSE------FVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYS 351
+ + +S + ST+ ++ + G L H + V F + + L S
Sbjct: 463 SPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLAS 522
Query: 352 GSRDCNILAW 361
GS D + W
Sbjct: 523 GSFDKCVHIW 532
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 66.6 bits (161), Expect = 4e-11
Identities = 62/260 (23%), Positives = 91/260 (35%), Gaps = 99/260 (38%)
Query: 55 EGRYMLSGGSDGVIVLYDLENSSRQSYYT------------------------CKAVCSI 90
+G Y+LS G D +++D + + C VC +
Sbjct: 340 KGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRL 399
Query: 91 GRDHP----DVHRYSVETVQWYPHDTGMFTSS-SFDKTLKVWDTNTLQTADVFNFEETVY 145
G D P H V ++W P +GM +S S D TLK+W
Sbjct: 400 GCDRPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWS----------------- 440
Query: 146 SHHMSPVSTKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSP--------R 197
+K C H LQ H +EI + WSP
Sbjct: 441 ---------------------------MKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPN 473
Query: 198 YDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDG 257
+ +LA+AS DS V+LWD+ R C TL T H V + F+ DG
Sbjct: 474 SNIMLASASFDSTVRLWDIERGV-CTHTL---------------TKHQEPVYSVAFSPDG 517
Query: 258 LHLLTVGTDNRMRLWNSSNG 277
+L + D + +WN+ +G
Sbjct: 518 KYLASGSFDKCVHIWNTQSG 537
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/137 (21%), Positives = 52/137 (37%), Gaps = 40/137 (29%)
Query: 181 ILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRAS-------------------- 220
+L+GH E+ +W+P D +LA+ S DS ++W++ S
Sbjct: 227 VLRGHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 285
Query: 221 --------------GCLITLDQHNGKKSQAVESANTA-----HNGKVNGLCFTSDGLHLL 261
G L+ ++G E N A H G + L + G ++L
Sbjct: 286 PSNKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYIL 345
Query: 262 TVGTDNRMRLWNSSNGE 278
+ G D +W++ GE
Sbjct: 346 SAGVDKTTIIWDAHTGE 362
Score = 35.0 bits (79), Expect = 0.12
Identities = 58/310 (18%), Positives = 109/310 (35%), Gaps = 54/310 (17%)
Query: 98 HRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYSH------HMSP 151
H V W P + + S S D T ++W+ N + V H H P
Sbjct: 231 HESEVFICAWNPV-SDLLASGSGDSTARIWNLNENSNG---GSTQLVLRHCIREGGHDVP 286
Query: 152 VS---------TKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYIL 202
+ T L+A G+ ++ + G+ + L H+ I A+ W+ + +YIL
Sbjct: 287 SNKDVTSLDWNTNGTLLATGSYDGFARIWT-EDGNLASTLGQHKGPIFALKWNRKGNYIL 345
Query: 203 ATASADSRVKLWDVRRA---------SGCLITLDQHNGKKSQAVES-------------- 239
+A D +WD S + +D N + +
Sbjct: 346 -SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRP 404
Query: 240 --ANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKF 297
H +VN + + G+ L + D +++W S + ++ + N +K+
Sbjct: 405 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIW--SMKQEVCIHDLQAHNKEIYTIKW 462
Query: 298 TVSCGCSSE------FVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYS 351
+ + +S + ST+ ++ + G L H + V F + + L S
Sbjct: 463 SPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLAS 522
Query: 352 GSRDCNILAW 361
GS D + W
Sbjct: 523 GSFDKCVHIW 532
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 66.6 bits (161), Expect = 4e-11
Identities = 70/280 (25%), Positives = 121/280 (43%), Gaps = 59/280 (21%)
Query: 98 HRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYSHHMS----PVS 153
H +V +V++ P+ + SSS D+ + +W A +E+T+Y H++ S
Sbjct: 40 HTEAVSSVKFSPNGEWL-ASSSADRLIIIWG------AYDGKYEKTLYGHNLEISDVAWS 92
Query: 154 TKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKL 213
+ + + ++L D++SG C L+GH + +++P + I++ S D VK+
Sbjct: 93 SDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIIS-GSFDETVKI 151
Query: 214 WDVRRASGCLITLDQHNGKKSQAVE---SANTAHNGKVNGLC------------------ 252
W+V+ CL TL H+ S AV S + +G +GLC
Sbjct: 152 WEVKTGK-CLKTLSAHSDPVS-AVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDD 209
Query: 253 --------FTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYG----KVC---NNSKKGLKF 297
F+ +G ++LT DN ++LW+ S G G K C N S G K+
Sbjct: 210 NPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKW 269
Query: 298 TVSCGCSSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTV 337
VS G V+ ++ + + E + L+GH V
Sbjct: 270 IVS-GSEDNLVY--------IWNLQTKEIVQKLQGHTDVV 300
Score = 43.5 bits (101), Expect = 3e-04
Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 5/126 (3%)
Query: 236 AVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGL 295
A++ H V+ + F+ +G L + D + +W + +G+ Y K +
Sbjct: 32 ALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGK-----YEKTLYGHNLEI 86
Query: 296 KFTVSCGCSSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRD 355
SS V T+ ++ V SG+ + LKGH V CC F + SGS D
Sbjct: 87 SDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFD 146
Query: 356 CNILAW 361
+ W
Sbjct: 147 ETVKIW 152
>gi|102470001 PQQ repeat and WD repeat domain containing [Homo
sapiens]
Length = 472
Score = 66.2 bits (160), Expect = 5e-11
Identities = 75/323 (23%), Positives = 136/323 (42%), Gaps = 41/323 (12%)
Query: 54 VEGRYMLSGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYSVETVQW-YPHDT 112
V+ +LSG D + L+D + S + RD HR V+ D+
Sbjct: 112 VDDTKLLSGSYDCTVKLWDPVDGS------------VVRDFE--HRPKAPVVECSITGDS 157
Query: 113 GMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCLVAVGTRGPKVQLCD 172
++S+DKT++ WD T + ++ + S SP +V+ + + D
Sbjct: 158 SRVIAASYDKTVRAWDLETGKLLWKVRYDTFIVSCKFSPDGKY--VVSGFDVDHGICIMD 215
Query: 173 LKSGSCSHILQGHR-QEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNG 231
++ + +++ H + I + + P + A+ S D +K+WDV + L+T+ +
Sbjct: 216 AENITTVSVIKDHHTRSITSCCFDPDSQRV-ASVSLDRCIKIWDVT-SQATLLTITK--- 270
Query: 232 KKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNS 291
AH+ ++ CFT G L T D +++WN GE N G C
Sbjct: 271 -----------AHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGE--FRNCG-ACVTL 316
Query: 292 KKGLKFTV-SCGCSSEFVFVPYGS---TIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQ 347
+G + +V SC + + F+ G T+A++ V G + LKGH V +N +
Sbjct: 317 MQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAISNNKK 376
Query: 348 ELYSGSRDCNILAWVPSLYEPVP 370
+ S S+D + W + +P
Sbjct: 377 WILSASKDRTMRLWNIEEIDEIP 399
Score = 31.2 bits (69), Expect = 1.7
Identities = 14/35 (40%), Positives = 18/35 (51%)
Query: 329 MLKGHYKTVDCCVFQSNFQELYSGSRDCNILAWVP 363
+L GH V C F + +L SGS DC + W P
Sbjct: 97 ILSGHEHAVSTCHFCVDDTKLLSGSYDCTVKLWDP 131
>gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo
sapiens]
Length = 421
Score = 65.5 bits (158), Expect = 8e-11
Identities = 60/216 (27%), Positives = 102/216 (47%), Gaps = 20/216 (9%)
Query: 63 GSDGVIVLYDLENSSRQSY--YTCKAVCSIGRDHPDVHRYSVETVQWYPHDTGMFTSSSF 120
G D +++ L N + + YT K + ++ DH +V V + + P + + S+S
Sbjct: 137 GQDQLLLATGLNNGRIKIWDVYTGKLLLNLV-DHTEV----VRDLTFAPDGSLILVSASR 191
Query: 121 DKTLKVWDT----NTLQTADVFNFEETVYSHHMSPVSTKHCLVAVGTRGPKVQLCDLKSG 176
DKTL+VWD N ++ + + VYS SP S+ C V V L ++
Sbjct: 192 DKTLRVWDLKDDGNMMKV--LRGHQNWVYSCAFSPDSSMLCSVGASKA---VFLWNMDKY 246
Query: 177 SCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQA 236
+ L+GH +++A +SP +LATAS D+RV +WD I ++ +
Sbjct: 247 TMIRKLEGHHHDVVACDFSPD-GALLATASYDTRVYIWDPHNGD---ILMEFGHLFPPPT 302
Query: 237 VESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLW 272
A A++ V + F+ DGLH+ ++ D +R W
Sbjct: 303 PIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFW 338
Score = 43.9 bits (102), Expect = 3e-04
Identities = 39/164 (23%), Positives = 62/164 (37%), Gaps = 21/164 (12%)
Query: 201 ILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDG-LH 259
+LAT + R+K+WDV L +D H V L F DG L
Sbjct: 142 LLATGLNNGRIKIWDVYTGKLLLNLVD----------------HTEVVRDLTFAPDGSLI 185
Query: 260 LLTVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKFTVSCGCSSEFVFVPYGSTIAVY 319
L++ D +R+W+ + N + KV + + SS V + ++
Sbjct: 186 LVSASRDKTLRVWDLKDDGNMM----KVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLW 241
Query: 320 TVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILAWVP 363
+ I L+GH+ V C F + L + S D + W P
Sbjct: 242 NMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDP 285
Score = 42.4 bits (98), Expect = 7e-04
Identities = 32/155 (20%), Positives = 63/155 (40%), Gaps = 28/155 (18%)
Query: 158 LVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVR 217
L+A G ++++ D+ +G L H + + ++++P IL +AS D +++WD++
Sbjct: 142 LLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLK 201
Query: 218 RASGCLITLDQHNGKKSQAVESANTA---------------------------HNGKVNG 250
+ L H S +++ H+ V
Sbjct: 202 DDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVA 261
Query: 251 LCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYG 285
F+ DG L T D R+ +W+ NG+ L+ +G
Sbjct: 262 CDFSPDGALLATASYDTRVYIWDPHNGD-ILMEFG 295
>gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo
sapiens]
Length = 275
Score = 63.5 bits (153), Expect = 3e-10
Identities = 53/184 (28%), Positives = 87/184 (47%), Gaps = 17/184 (9%)
Query: 93 DHPDVHRYSVETVQWYPHDTGMFTSSSFDKTLKVWDT----NTLQTADVFNFEETVYSHH 148
DH +V V + + P + + S+S DKTL+VWD N ++ + + VYS
Sbjct: 22 DHTEV----VRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKV--LRGHQNWVYSCA 75
Query: 149 MSPVSTKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASAD 208
SP S+ C V V L ++ + L+GH +++A +SP +LATAS D
Sbjct: 76 FSPDSSMLCSVGASKA---VFLWNMDKYTMIRKLEGHHHDVVACDFSPD-GALLATASYD 131
Query: 209 SRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNR 268
+RV +WD I ++ + A A++ V + F+ DGLH+ ++ D
Sbjct: 132 TRVYIWDPHNGD---ILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKM 188
Query: 269 MRLW 272
+R W
Sbjct: 189 VRFW 192
Score = 36.6 bits (83), Expect = 0.041
Identities = 30/129 (23%), Positives = 59/129 (45%), Gaps = 19/129 (14%)
Query: 158 LVAVGTRGPKVQLCDLKS-GSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDV 216
++ +R +++ DLK G+ +L+GH+ + + ++SP +L + A V LW+
Sbjct: 39 ILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSS-MLCSVGASKAVFLWN- 96
Query: 217 RRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSN 276
+D++ + H+ V F+ DG L T D R+ +W+ N
Sbjct: 97 ---------MDKYTMIRKLE------GHHHDVVACDFSPDGALLATASYDTRVYIWDPHN 141
Query: 277 GENTLVNYG 285
G+ L+ +G
Sbjct: 142 GD-ILMEFG 149
Score = 36.2 bits (82), Expect = 0.053
Identities = 29/121 (23%), Positives = 47/121 (38%), Gaps = 5/121 (4%)
Query: 244 HNGKVNGLCFTSDG-LHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKFTVSCG 302
H V L F DG L L++ D +R+W+ + N + KV + +
Sbjct: 23 HTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMM----KVLRGHQNWVYSCAFSP 78
Query: 303 CSSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILAWV 362
SS V + ++ + I L+GH+ V C F + L + S D + W
Sbjct: 79 DSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWD 138
Query: 363 P 363
P
Sbjct: 139 P 139
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 62.8 bits (151), Expect = 5e-10
Identities = 76/321 (23%), Positives = 129/321 (40%), Gaps = 44/321 (13%)
Query: 42 HGGGINTLDIEPVEGRYMLSGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYS 101
H G + P G + S G D +I+L+++ +Y T K H +
Sbjct: 65 HEGEVYCCKFHP-NGSTLASAGFDRLILLWNVYGDC-DNYATLKG-----------HSGA 111
Query: 102 VETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCLVAV 161
V + Y D M S+S DKT+ VWD+ T + T + + P LV
Sbjct: 112 VMELH-YNTDGSMLFSASTDKTVAVWDSETGERVKRLK-GHTSFVNSCYPARRGPQLVCT 169
Query: 162 GTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASG 221
G+ V+L D++ + Q Q +LAV+++ D I++ D+ +K+WD+R+
Sbjct: 170 GSDDGTVKLWDIRKKAAIQTFQNTYQ-VLAVTFNDTSDQIIS-GGIDNDIKVWDLRQ--- 224
Query: 222 CLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWN----SSNG 277
+ H V GL +S+G +LL+ DN +R+W+ +
Sbjct: 225 -------------NKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKE 271
Query: 278 ENTLVNYGKVCNNSKKGLKFTVSCGCSSEFVFVPYGST---IAVYTVYSGEQITMLKGHY 334
+ G V N K L+ C S + + GS + V+ S + L GH
Sbjct: 272 RCVKIFQGNVHNFEKNLLR----CSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHA 327
Query: 335 KTVDCCVFQSNFQELYSGSRD 355
+++ F + + S S D
Sbjct: 328 GSINEVAFHPDEPIIISASSD 348
Score = 42.0 bits (97), Expect = 0.001
Identities = 40/186 (21%), Positives = 70/186 (37%), Gaps = 31/186 (16%)
Query: 181 ILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESA 240
+L GH E+ + P LA+A D + LW+V TL
Sbjct: 61 LLSGHEGEVYCCKFHPNGS-TLASAGFDRLILLWNVYGDCDNYATLK------------- 106
Query: 241 NTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTL-----VNYGKVCNNSKKGL 295
H+G V L + +DG L + TD + +W+S GE ++ C +++G
Sbjct: 107 --GHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGP 164
Query: 296 KFTVSCGCSSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRD 355
+ C S + T+ ++ + I + Y+ + F ++ SG D
Sbjct: 165 QLV--CTGSDD-------GTVKLWDIRKKAAIQTFQNTYQVL-AVTFNDTSDQIISGGID 214
Query: 356 CNILAW 361
+I W
Sbjct: 215 NDIKVW 220
Score = 28.9 bits (63), Expect = 8.5
Identities = 15/35 (42%), Positives = 16/35 (45%)
Query: 327 ITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILAW 361
I +L GH V CC F N L S D IL W
Sbjct: 59 IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLW 93
>gi|4557515 damage-specific DNA binding protein 2 [Homo sapiens]
Length = 427
Score = 62.4 bits (150), Expect = 7e-10
Identities = 51/178 (28%), Positives = 86/178 (48%), Gaps = 20/178 (11%)
Query: 101 SVETVQWYPHDTGMFTSSSFDKTLKVWDT--NTLQTADVFNFEETVYSHHMS-PVSTKHC 157
S+ +++ P +T F +SS + T ++ D N L+ VF +T+ S VS
Sbjct: 158 SITGLKFNPLNTNQFYASSMEGTTRLQDFKGNILR---VFASSDTINIWFCSLDVSASSR 214
Query: 158 LVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVR 217
+V G V L ++ G L+ H++++ V+ +P D+ LATAS D VK+WD+R
Sbjct: 215 MVVTGDNVGNVILLNM-DGKELWNLRMHKKKVTHVALNPCCDWFLATASVDQTVKIWDLR 273
Query: 218 RASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSS 275
+ G +A + H VN CF+ DG LLT + +R++++S
Sbjct: 274 QVRG-------------KASFLYSLPHRHPVNAACFSPDGARLLTTDQKSEIRVYSAS 318
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,342,144
Number of Sequences: 37866
Number of extensions: 670594
Number of successful extensions: 3496
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 148
Number of HSP's successfully gapped in prelim test: 139
Number of HSP's that attempted gapping in prelim test: 1764
Number of HSP's gapped (non-prelim): 1182
length of query: 396
length of database: 18,247,518
effective HSP length: 104
effective length of query: 292
effective length of database: 14,309,454
effective search space: 4178360568
effective search space used: 4178360568
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.