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Search of human proteins with 4557441
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
sapiens]
(316 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ... 629 0.0
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 610 e-175
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 610 e-175
gi|72004269 tetra-peptide repeat homeobox [Homo sapiens] 95 7e-20
gi|45120115 hypothetical protein LOC56905 [Homo sapiens] 90 2e-18
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 89 4e-18
gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 88 9e-18
gi|4503519 eukaryotic translation initiation factor 3, subunit 5... 81 1e-15
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 80 2e-15
gi|210032509 hypothetical protein LOC100130302 [Homo sapiens] 78 9e-15
gi|19111150 angiomotin isoform 2 [Homo sapiens] 78 1e-14
gi|166064029 angiomotin isoform 1 [Homo sapiens] 78 1e-14
gi|33356148 formin-like 1 [Homo sapiens] 78 1e-14
gi|33286436 gametogenetin [Homo sapiens] 77 2e-14
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 77 2e-14
gi|4757962 cyclin-dependent kinase inhibitor 1B [Homo sapiens] 75 8e-14
gi|24307909 ral guanine nucleotide dissociation stimulator isofo... 74 2e-13
gi|108796058 ral guanine nucleotide dissociation stimulator isof... 74 2e-13
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 72 6e-13
gi|153792074 proline rich 12 [Homo sapiens] 72 6e-13
gi|110832843 TBP-associated factor 4 [Homo sapiens] 72 8e-13
gi|68563515 keratinocyte proline-rich protein [Homo sapiens] 71 1e-12
gi|153791535 general control of amino acid synthesis 5-like 2 [H... 70 2e-12
gi|47132519 Ras association and pleckstrin homology domains 1 is... 69 4e-12
gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog ... 68 9e-12
gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog ... 68 9e-12
gi|163965366 nascent polypeptide-associated complex alpha subuni... 68 9e-12
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 67 2e-11
gi|167614488 TBC1 domain family, member 10B [Homo sapiens] 67 3e-11
gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo ... 66 4e-11
>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
sapiens]
Length = 316
Score = 629 bits (1623), Expect = 0.0
Identities = 316/316 (100%), Positives = 316/316 (100%)
Query: 1 MSDASLRSTSTMERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNR 60
MSDASLRSTSTMERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNR
Sbjct: 1 MSDASLRSTSTMERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNR 60
Query: 61 WDYDFQQDMPLRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLE 120
WDYDFQQDMPLRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLE
Sbjct: 61 WDYDFQQDMPLRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLE 120
Query: 121 PAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAP 180
PAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAP
Sbjct: 121 PAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAP 180
Query: 181 APAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLAD 240
APAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLAD
Sbjct: 181 APAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLAD 240
Query: 241 QLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSA 300
QLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSA
Sbjct: 241 QLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSA 300
Query: 301 APGVGSVEQTPRKRLR 316
APGVGSVEQTPRKRLR
Sbjct: 301 APGVGSVEQTPRKRLR 316
>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 610 bits (1573), Expect = e-175
Identities = 305/305 (100%), Positives = 305/305 (100%)
Query: 12 MERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPL 71
MERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPL
Sbjct: 1 MERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPL 60
Query: 72 RGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEE 131
RGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEE
Sbjct: 61 RGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEE 120
Query: 132 APEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA 191
APEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA
Sbjct: 121 APEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA 180
Query: 192 PAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPA 251
PAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPA
Sbjct: 181 PAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPA 240
Query: 252 AGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTP 311
AGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTP
Sbjct: 241 AGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTP 300
Query: 312 RKRLR 316
RKRLR
Sbjct: 301 RKRLR 305
>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 610 bits (1573), Expect = e-175
Identities = 305/305 (100%), Positives = 305/305 (100%)
Query: 12 MERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPL 71
MERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPL
Sbjct: 1 MERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPL 60
Query: 72 RGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEE 131
RGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEE
Sbjct: 61 RGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEE 120
Query: 132 APEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA 191
APEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA
Sbjct: 121 APEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA 180
Query: 192 PAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPA 251
PAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPA
Sbjct: 181 PAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPA 240
Query: 252 AGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTP 311
AGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTP
Sbjct: 241 AGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTP 300
Query: 312 RKRLR 316
RKRLR
Sbjct: 301 RKRLR 305
>gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]
Length = 411
Score = 95.1 bits (235), Expect = 7e-20
Identities = 69/244 (28%), Positives = 95/244 (38%), Gaps = 14/244 (5%)
Query: 67 QDMPLRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAV--AVSPPLEPAAE 124
Q P R PG+ + VPA Q G +L A P ++ A P A +
Sbjct: 27 QQQPQRVPGQRGRGARAAPLVPAASASAPQRGPSGILPAAEPTICSLHQAWGGPGCRAQK 86
Query: 125 SLDG-LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPA 183
+ L P +P+ P+P PA P P+P P P P PA + +P+ AP+ + P
Sbjct: 87 GIPAALSPGPGPIPA-PIPGPAQIPGPLPGSIPGPIPGPAQIPSPIPAPIPGPISGPVQI 145
Query: 184 PAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLH 243
P P P P P++ PAP P P P P P P P G G P+ +
Sbjct: 146 PGPFRGPIPGPISGPAPIPGPISGPFSGPNPGPIPGPNPGPIPGPISG-----PIPGPIS 200
Query: 244 SGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGD----VPAPCPSPS 299
I G P G + +G + GP+ P SG +P P P P
Sbjct: 201 VPIPG-PIPGPISGPISGPNPGPIPGPIPGPISGPNPGPIPGPISGPNPGLIPGPIPGPI 259
Query: 300 AAPG 303
+ PG
Sbjct: 260 SGPG 263
Score = 75.1 bits (183), Expect = 8e-14
Identities = 58/198 (29%), Positives = 72/198 (36%), Gaps = 32/198 (16%)
Query: 108 PVAVAVAVSPPLE-PAAESLDGLEEAPEQLP-SVPVPAPASTPPPVPVLAPAPAPAPAPV 165
P + +S P P + G P P S P+P P S P P P+ P P P
Sbjct: 160 PAPIPGPISGPFSGPNPGPIPGPNPGPIPGPISGPIPGPISVPIPGPIPGPISGPISGPN 219
Query: 166 AAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAE 225
P+ P+ P P P P P P P++ P P P P P P P P P S
Sbjct: 220 PGPIPGPI------PGPISGPNPGPIPGPISGPNPGLIPGPIPGPISGPGPIIGPIPSPA 273
Query: 226 QGANQGQ-RGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAP 284
Q G+ +G P+ L G P + A G SGP
Sbjct: 274 QIPGPGRLQGPGPI---LSPGRMRSPGSLPGLAPILGPG----SGP-------------- 312
Query: 285 EKSSGDVPAPCPSPSAAP 302
SG VPAP P P + P
Sbjct: 313 --GSGSVPAPIPGPGSLP 328
Score = 60.5 bits (145), Expect = 2e-09
Identities = 42/151 (27%), Positives = 62/151 (41%), Gaps = 40/151 (26%)
Query: 106 PRPVAVAVAVSPPLE-PAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAP 164
P P ++V + P+ P + + G P +P P+P P S P P P+ P P P
Sbjct: 194 PIPGPISVPIPGPIPGPISGPISGPNPGP--IPG-PIPGPISGPNPGPIPGPISGPNPGL 250
Query: 165 VAAPVAAPVAVA--VLAPAPAPAPAPAPA----PAPVAAPA------------------- 199
+ P+ P++ ++ P P+PA P P P P+ +P
Sbjct: 251 IPGPIPGPISGPGPIIGPIPSPAQIPGPGRLQGPGPILSPGRMRSPGSLPGLAPILGPGS 310
Query: 200 -------PAPAPAPAPAPAPAP----APDAA 219
PAP P P PAPAP +PDA+
Sbjct: 311 GPGSGSVPAPIPGPGSLPAPAPLWPQSPDAS 341
>gi|45120115 hypothetical protein LOC56905 [Homo sapiens]
Length = 1047
Score = 90.1 bits (222), Expect = 2e-18
Identities = 50/107 (46%), Positives = 58/107 (54%), Gaps = 20/107 (18%)
Query: 140 PVPAPASTPPPVPVLAPAPA-PAPAPVAAPVA-------------------APVAVAVLA 179
P P PA+ P P APAP PAP P + P+ +P AVAV +
Sbjct: 659 PAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVAS 718
Query: 180 PAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQ 226
PAPAPAP+PAPA A A A PAPAPAP PAPA +AP +S EQ
Sbjct: 719 PAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQ 765
Score = 60.8 bits (146), Expect = 1e-09
Identities = 52/149 (34%), Positives = 67/149 (44%), Gaps = 31/149 (20%)
Query: 74 PGRLQWTEVDSDSVPA--FYRETVQVGRCRLLLAPRPVAVAVAVSPPL------EPAAES 125
PG L V +D++P F+ + R +L P P+ AV S P +PA
Sbjct: 626 PG-LPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTP 684
Query: 126 LDG------LEEAPEQLP--SVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAV 177
G L + P + S+ +P+P + P APAP+PAPA
Sbjct: 685 TSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPA-------------- 730
Query: 178 LAPAPAPAPAPAPAPAPVAAPAPAPAPAP 206
A APA A PAPAPAPVA PAPA AP
Sbjct: 731 RAQAPASARDPAPAPAPVAGPAPASTSAP 759
Score = 38.1 bits (87), Expect = 0.010
Identities = 54/219 (24%), Positives = 86/219 (39%), Gaps = 20/219 (9%)
Query: 106 PRPVAVAVAVSP--PLEPAAESLDGLEEAPEQ--LPSVPV----PAPASTPPPVPVLAPA 157
P+P A A P +P +E + +EA E+ LPS P + P V+ +
Sbjct: 408 PQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDS 467
Query: 158 PAPAPAPVAAPVAAPV-AVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAP 216
P P P P A ++ A P+ P P V + AP PAP P
Sbjct: 468 PVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEP 527
Query: 217 DAAPQE-----SAEQGANQGQRGQEPLADQLHSGISG-RPAAGTAAAS-ANGAAIKKLSG 269
D+A E + +G ++G RG P + G SG +P G+ A +++K +
Sbjct: 528 DSATAEPDSAPATSEGQDKGCRGTLPAQE----GPSGSKPLRGSLKEEVALDLSVRKPTA 583
Query: 270 PLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVE 308
++ A ++ DVP S PG+ ++
Sbjct: 584 EASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKID 622
Score = 35.4 bits (80), Expect = 0.067
Identities = 44/185 (23%), Positives = 62/185 (33%), Gaps = 20/185 (10%)
Query: 129 LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAP 188
L + Q P +P + P P AP PAP+P P P AP P
Sbjct: 325 LRQQAAQAPYIPPLGLDAYPYPS---APLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYA 381
Query: 189 APAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISG 248
+ A +P P A PQ A Q A Q +P ++ +
Sbjct: 382 RDDLSLYGA-----SPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPV------ 430
Query: 249 RPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVE 308
RPA + + K+ P +S+ S P D P PC P+ P +
Sbjct: 431 RPAQEAEEKTWLPSCRKEKLQPRLSE------HSGPPIVIRDSPVPCTPPALPPCARECQ 484
Query: 309 QTPRK 313
P+K
Sbjct: 485 SLPQK 489
Score = 34.3 bits (77), Expect = 0.15
Identities = 38/124 (30%), Positives = 49/124 (39%), Gaps = 23/124 (18%)
Query: 195 VAAPAPAPA------PAPAPAPA-PAPAPDAAPQESAEQGANQGQR--GQEPLADQLHSG 245
+ PAP PA P APAP PAP P + P G R Q+PL+ S
Sbjct: 656 ILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGP---------IGLRILAQQPLSVTCFSL 706
Query: 246 ISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVG 305
P A A+ A A P + A P + V P P+ ++APG
Sbjct: 707 ALPSPPAVAVASPAPAPA----PSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPG-D 761
Query: 306 SVEQ 309
S+EQ
Sbjct: 762 SLEQ 765
>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
Length = 1711
Score = 89.4 bits (220), Expect = 4e-18
Identities = 55/119 (46%), Positives = 60/119 (50%), Gaps = 10/119 (8%)
Query: 103 LLAPRPVAVAVAVS-PPLE----PAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPA 157
L AP P ++V VS PPL P S L AP P V P PASTPP APA
Sbjct: 297 LSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTP-VLAPMPASTPPA----APA 351
Query: 158 PAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAP 216
P P P P + P + L PA AP P PAP PAP+ PAP P PA PA P AP
Sbjct: 352 PPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAP 410
Score = 89.0 bits (219), Expect = 5e-18
Identities = 68/173 (39%), Positives = 74/173 (42%), Gaps = 52/173 (30%)
Query: 104 LAPRPVAVAV-AVSPPLEPAAESLDGLEEAPEQLP-------------SVPVPAPASTPP 149
L P VA +V A SPPL P + L AP +P SV VP PAS PP
Sbjct: 236 LVPVQVATSVPAPSPPLAP----VPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPP 291
Query: 150 --PVPVLAPAPAPAPAPVAAP----------------VAAPVAVAVLAPAPAPAPAPAPA 191
PVP+ APAPAP PV+AP V APV VLAP PA P APA
Sbjct: 292 SGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPA 351
Query: 192 PAPVAAPAP----------------APAPAPAPAPAPAPAPDAAPQESAEQGA 228
P V P P AP P PAP PAP P P +A A
Sbjct: 352 PPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAA 404
Score = 76.6 bits (187), Expect = 3e-14
Identities = 67/220 (30%), Positives = 84/220 (38%), Gaps = 52/220 (23%)
Query: 115 VSPPLEPAAESLDGLEEAPEQLPSVPVPAP----------ASTPPPVPVLAPAPAPAPAP 164
+ PP +A + +A + SVP P P S P P P LAP PA APAP
Sbjct: 203 ICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAP 262
Query: 165 VAAPVAAP------VAVAVLAPAPA------PAPAPAPAPAPVAAPAPAP------APAP 206
+ P V+ +VL P PA P P APAPAP++ P AP AP P
Sbjct: 263 PSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVP 322
Query: 207 APAP----APAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGA 262
AP AP P P AP ++ A PA +
Sbjct: 323 PSAPTLVLAPVPTPVLAPMPASTPPA--------------------APAPPSVPMPTPTP 362
Query: 263 AIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAP 302
+ S P + FA AP + PAP P P+A P
Sbjct: 363 SSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATP 402
Score = 71.2 bits (173), Expect = 1e-12
Identities = 44/108 (40%), Positives = 49/108 (45%), Gaps = 22/108 (20%)
Query: 102 LLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPA 161
L+LAP P V + PAA AP +P +P P P+S PP P L PA AP
Sbjct: 328 LVLAPVPTPVLAPMPASTPPAAP-------APPSVP-MPTPTPSSGPPSTPTLIPAFAPT 379
Query: 162 PAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 209
P P AP PAP PAP P P A PA P AP PA
Sbjct: 380 PVP--------------APTPAPIFTPAPTPMPAATPAAIPTSAPIPA 413
Score = 68.6 bits (166), Expect = 7e-12
Identities = 55/185 (29%), Positives = 78/185 (42%), Gaps = 26/185 (14%)
Query: 138 SVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAA 197
++P+ +P P P+ PAP A P + P A V ++V PAP P P VA
Sbjct: 188 TLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSV----PAPVPHSGLVPVQVAT 243
Query: 198 PAPAPAPAPAPAPAPAPAPDAAPQESAEQG-------------ANQGQRGQEPLA----D 240
PAP+P AP PA APAP + P ++ A+ G PL+
Sbjct: 244 SVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPA 303
Query: 241 QLHSGISGRPAA---GTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPS 297
L +S P A SA + + P+++ A +AP S VP P P+
Sbjct: 304 PLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPS--VPMPTPT 361
Query: 298 PSAAP 302
PS+ P
Sbjct: 362 PSSGP 366
Score = 34.3 bits (77), Expect = 0.15
Identities = 32/116 (27%), Positives = 48/116 (41%), Gaps = 22/116 (18%)
Query: 144 PASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAP-APAPAPAPAPVAAPAPAP 202
P ++P PAP P P+ A + A A + P P P PAP+ + AP P PA
Sbjct: 527 PCTSPSGSTTTQPAPDGVPGPL-ADTSLVTASAKVLPTPQPLLPAPSGSSAP---PHPAK 582
Query: 203 AP--------------APAPAPAPAPAPDAAPQESAEQG---ANQGQRGQEPLADQ 241
P +P +P A+P E +E +++ R + PL +Q
Sbjct: 583 MPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQ 638
Score = 31.2 bits (69), Expect = 1.3
Identities = 35/134 (26%), Positives = 44/134 (32%), Gaps = 8/134 (5%)
Query: 177 VLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAP---QESAEQGANQGQR 233
+LA P P +P PAP PAP A P + P Q A
Sbjct: 175 ILATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHS 234
Query: 234 GQEPLADQLHSGISGRPAAGTAAASANGAAIKKL---SGPLISDFFAKRKRSAPEKSSGD 290
G P+ P A A + ++ L S PL A SG
Sbjct: 235 GLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGP 294
Query: 291 VP--APCPSPSAAP 302
VP AP P+P + P
Sbjct: 295 VPLSAPAPAPLSVP 308
>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
Length = 1271
Score = 88.2 bits (217), Expect = 9e-18
Identities = 52/131 (39%), Positives = 62/131 (47%), Gaps = 17/131 (12%)
Query: 107 RPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVL----APAPAPAP 162
R A A +PP + + E+PE P P P P PPP P L +P P P P
Sbjct: 3 RGAAAAQGTAPPQDGEQPA-----ESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEP 57
Query: 163 APVAAPVAAPVAVAVLA--------PAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAP 214
P AP P A + A P PA PA PAP P PAP PA PAP PAP P
Sbjct: 58 CPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEP 117
Query: 215 APDAAPQESAE 225
A ++AP+ + E
Sbjct: 118 ATESAPEPTPE 128
Score = 70.9 bits (172), Expect = 1e-12
Identities = 46/132 (34%), Positives = 56/132 (42%), Gaps = 12/132 (9%)
Query: 106 PRPVAVAVAVSPPL-EPAAESLDG-----LEEAPEQLPSVPVPAPASTPPPVPVLAPAPA 159
P P ++ A P+ EP E G E+ +L + P P PA+ P P PA
Sbjct: 41 PAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATE 100
Query: 160 PAPAPVAAPVAAPVAVAVLAPAPAPAPAPA----PAPAPVAAPAPAP--APAPAPAPAPA 213
PAP P P P AP P P PA P PAP P AP AP P P P
Sbjct: 101 PAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTE 160
Query: 214 PAPDAAPQESAE 225
AP+ P+ + E
Sbjct: 161 LAPEFCPEAAPE 172
Score = 69.7 bits (169), Expect = 3e-12
Identities = 44/107 (41%), Positives = 50/107 (46%), Gaps = 4/107 (3%)
Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQ-LPSVPVPAPASTPPPVPVLAPAPAPAPA 163
AP P A A P EPA ES E PE L SVP PAP TP P LAP P P P
Sbjct: 102 APEP-ATEPAPEPAPEPATESAP--EPTPEPALESVPEPAPELTPEVAPELAPEPTPEPV 158
Query: 164 PVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAP 210
AP P A P+PAP P +P+P+P+P+P
Sbjct: 159 TELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSP 205
Score = 69.3 bits (168), Expect = 4e-12
Identities = 49/143 (34%), Positives = 59/143 (41%), Gaps = 20/143 (13%)
Query: 105 APRPV---AVAVAVSPPLEPAAESLDGLEEAPEQLP-----SVPVPAPASTPPPVPVLAP 156
+P P+ +A P E +ES L P P S P P PA+ P P P P
Sbjct: 50 SPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEP 109
Query: 157 APAPAPAPV--AAPVAAPVAVAVLAPAPAP----------APAPAPAPAPVAAPAPAPAP 204
AP PAP P +AP P P PAP AP P P P AP P
Sbjct: 110 APEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEA 169
Query: 205 APAPAPAPAPAPDAAPQESAEQG 227
AP P+PAP P ++ E+G
Sbjct: 170 APEFRPSPAPCLLQCPVDTRERG 192
Score = 60.5 bits (145), Expect = 2e-09
Identities = 49/140 (35%), Positives = 56/140 (40%), Gaps = 8/140 (5%)
Query: 81 EVDSDSVPAFYRETVQVGRCRLLLAPRPV-AVAVAVSPPLEPAAESLDGLEEAPEQLPS- 138
E S+S Y E P P A A P EPA E E A E P
Sbjct: 68 EATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAP--EPATESAPEP 125
Query: 139 VPVPAPASTPPPVPVLAPAPAP--APAPVAAPVA--APVAVAVLAPAPAPAPAPAPAPAP 194
P PA S P P P L P AP AP P PV AP AP P+PAP P
Sbjct: 126 TPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCP 185
Query: 195 VAAPAPAPAPAPAPAPAPAP 214
V +P+P+P+P+P
Sbjct: 186 VDTRERGLKTSPSPSPSPSP 205
Score = 52.4 bits (124), Expect = 5e-07
Identities = 48/174 (27%), Positives = 58/174 (33%), Gaps = 41/174 (23%)
Query: 143 APASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAP------APAPAPAPVA 196
A T PP PA +P P P P P PAP PAP +P P P P
Sbjct: 7 AAQGTAPPQDGEQPAESPEPPPPWPPPPPP-------PAPPPAPPLLSEASPEPIPEPCP 59
Query: 197 APAPAPAP------------APAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHS 244
AP P P P P PA PA + AP+ + E EP +
Sbjct: 60 ELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEP-------APEPATE---- 108
Query: 245 GISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSP 298
PA A A +A + P + PE + P P P P
Sbjct: 109 -----PAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEP 157
Score = 46.6 bits (109), Expect = 3e-05
Identities = 32/116 (27%), Positives = 45/116 (38%), Gaps = 5/116 (4%)
Query: 184 PAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLH 243
PA +P P P P P P PAP PAP +P+ P+ E A +L+
Sbjct: 20 PAESPEPPP-PWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELY 78
Query: 244 SGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPS 299
+ + PA A+ A A + P APE ++ P P P P+
Sbjct: 79 TEPTPEPATEPASEPAPEPATEPAPEPATE----PAPEPAPEPATESAPEPTPEPA 130
>gi|4503519 eukaryotic translation initiation factor 3, subunit 5
epsilon, 47kDa [Homo sapiens]
Length = 357
Score = 81.3 bits (199), Expect = 1e-15
Identities = 46/84 (54%), Positives = 50/84 (59%), Gaps = 4/84 (4%)
Query: 137 PSVPVPAPASTPPPVPVLAPA--PAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAP 194
P+VPV AP +TP PVP APA PAP PAP AAPV A + PA A A AP P
Sbjct: 4 PAVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQTP 63
Query: 195 VAAPAPAPAPAPA-PAPA-PAPAP 216
+A APA PAPA P PA P P P
Sbjct: 64 ASAQAPAQTPAPALPGPALPGPFP 87
Score = 67.4 bits (163), Expect = 2e-11
Identities = 35/75 (46%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Query: 149 PPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAP 208
P VPV AP P P P AAP + P AP PAPA AP PA AP ++ PA A A
Sbjct: 4 PAVPVSAPPATPTPVPAAAPASVP------APTPAPAAAPVPAAAPASSSDPAAAAAATA 57
Query: 209 APAPAPAPDAAPQES 223
AP PA AP ++
Sbjct: 58 APGQTPASAQAPAQT 72
Score = 63.9 bits (154), Expect = 2e-10
Identities = 33/61 (54%), Positives = 37/61 (60%)
Query: 163 APVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQE 222
A A PV+AP A PA APA PAP PAP AAP PA APA + PA A A AAP +
Sbjct: 2 ATPAVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQ 61
Query: 223 S 223
+
Sbjct: 62 T 62
Score = 61.2 bits (147), Expect = 1e-09
Identities = 32/62 (51%), Positives = 34/62 (54%)
Query: 159 APAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDA 218
A PV+AP A P V APA PAP PAPA APV A APA + PA A A AP
Sbjct: 2 ATPAVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQ 61
Query: 219 AP 220
P
Sbjct: 62 TP 63
Score = 58.5 bits (140), Expect = 7e-09
Identities = 31/60 (51%), Positives = 33/60 (55%)
Query: 171 APVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQ 230
A AV V AP P P PA APA V AP PAPA AP PA APA + D A +A Q
Sbjct: 2 ATPAVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQ 61
Score = 58.5 bits (140), Expect = 7e-09
Identities = 29/57 (50%), Positives = 32/57 (56%)
Query: 176 AVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQ 232
AV AP P P PA AP + PAP PAPA AP PA APA + P +A A GQ
Sbjct: 5 AVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQ 61
Score = 55.5 bits (132), Expect = 6e-08
Identities = 30/67 (44%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
Query: 178 LAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQR---G 234
+A P AP P PV A APA PAP PAPA AP P AAP S++ A G
Sbjct: 1 MATPAVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPG 60
Query: 235 QEPLADQ 241
Q P + Q
Sbjct: 61 QTPASAQ 67
Score = 41.2 bits (95), Expect = 0.001
Identities = 32/108 (29%), Positives = 37/108 (34%), Gaps = 22/108 (20%)
Query: 189 APAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISG 248
A PV+AP P P PA APA PAP AP + A S
Sbjct: 2 ATPAVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPAS--------------SS 47
Query: 249 RPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCP 296
PAA AA +A G P + AP +P P P
Sbjct: 48 DPAAAAAATAAPGQTPASAQAP--------AQTPAPALPGPALPGPFP 87
Score = 29.6 bits (65), Expect = 3.7
Identities = 24/61 (39%), Positives = 27/61 (44%), Gaps = 10/61 (16%)
Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPA-PAPA 163
AP P A + S P AA + AP Q P+ APA TP P P PA P P
Sbjct: 36 APVPAAAPASSSDPAAAAAATA-----APGQTPA-SAQAPAQTPAPA---LPGPALPGPF 86
Query: 164 P 164
P
Sbjct: 87 P 87
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 80.1 bits (196), Expect = 2e-15
Identities = 72/212 (33%), Positives = 91/212 (42%), Gaps = 32/212 (15%)
Query: 104 LAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPS-VPVPAPASTPPPVPVLAPAP---- 158
LAP + +V+ S P +A ++ AP P+ P+ A STP V +LA A
Sbjct: 1806 LAPVSASASVSASVPASTSAAAITS-SSAPASAPAPTPILASVSTPASVTILASASIPIL 1864
Query: 159 --------APAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAP 210
AP PAP A+ AAPV A PA AP + APA +APAPAP P AP P
Sbjct: 1865 ASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNP 1924
Query: 211 APAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGP 270
AP PAP A+ A + Q PL Q S S +P SA P
Sbjct: 1925 AP-PAP-------AQTQAQTHKPVQNPL--QTTSQSSKQPPPSIRLPSA--------QTP 1966
Query: 271 LISDFFAKRKRSAPEKSSGDVPAPCPSPSAAP 302
+D+ A K +S G + A AP
Sbjct: 1967 NGTDYVASGKSIQTPQSHGTLTAELWDNKVAP 1998
Score = 75.9 bits (185), Expect = 4e-14
Identities = 71/213 (33%), Positives = 88/213 (41%), Gaps = 16/213 (7%)
Query: 98 GRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPV-LAP 156
GR + P A A ++ S+ L AP PS PAST P+P L P
Sbjct: 1718 GRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLP-PSTSASVPASTSAPLPATLTP 1776
Query: 157 APAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPA------PAP 210
PA APV A APV + AP PA AP A A V+A PA A A PA
Sbjct: 1777 VPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPAS 1836
Query: 211 APAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGP 270
APAP P A + LA L S +A T A +A+ A ++ P
Sbjct: 1837 APAPTPILASVSTPASVTILASASIPILASALAS-----TSAPTPAPAASSPAAPVITAP 1891
Query: 271 LI-SDFFAKRKRSAPEKSSGDVPAPCPSPSAAP 302
I + AP +S PAP P+P +AP
Sbjct: 1892 TIPASAPTASVPLAPASASA--PAPAPTPVSAP 1922
Score = 73.6 bits (179), Expect = 2e-13
Identities = 66/199 (33%), Positives = 78/199 (39%), Gaps = 13/199 (6%)
Query: 105 APRPVAVAVAVSPPLEPAAE-SLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPA 163
A +V S PL P+ S+ AP PVPA S P P LAP A A
Sbjct: 1740 AQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSA 1799
Query: 164 PVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQES 223
PV A APV+ + A PA A A +APA APAP P A PA +
Sbjct: 1800 PVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASA 1859
Query: 224 AEQGANQGQRGQEPLADQL--HSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKR 281
+ LA L S + PAA + AA A S P S A
Sbjct: 1860 S----------IPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASA 1909
Query: 282 SAPEKSSGDVPAPCPSPSA 300
SAP + V AP P+P A
Sbjct: 1910 SAPAPAPTPVSAPNPAPPA 1928
Score = 64.3 bits (155), Expect = 1e-10
Identities = 55/198 (27%), Positives = 72/198 (36%), Gaps = 11/198 (5%)
Query: 84 SDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEP---AAESLDGLEEAPEQLPSVP 140
S SVPA AP P + +VS P A+ S+ L A S P
Sbjct: 1816 SASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALAST-SAP 1874
Query: 141 VPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPA-------PAPAPAPA 193
PAPA++ P PV+ PA AP A+ AP + + APAP P PAPA A
Sbjct: 1875 TPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQA 1934
Query: 194 PVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAG 253
P P + + P P G + G+ Q H ++
Sbjct: 1935 QTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDN 1994
Query: 254 TAAASANGAAIKKLSGPL 271
A A I K GP+
Sbjct: 1995 KVAPPAVLNDISKKLGPI 2012
>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
Length = 887
Score = 78.2 bits (191), Expect = 9e-15
Identities = 67/174 (38%), Positives = 79/174 (45%), Gaps = 19/174 (10%)
Query: 71 LRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVS------PPLEPAAE 124
++GPG++ S S PA Q+ + P PV V +VS PP
Sbjct: 416 VKGPGKMS----HSSSGPA---SVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLP 468
Query: 125 SLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAP 184
S G + P P A +P P A A A A AA AA A A APAPA
Sbjct: 469 SSSGKISSGNSFP----PQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAA--APAPAL 522
Query: 185 APAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPL 238
A A APA A AAPA A A APAPAPA APA AAP +A + Q+ PL
Sbjct: 523 AAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPL 576
Score = 62.4 bits (150), Expect = 5e-10
Identities = 56/172 (32%), Positives = 71/172 (41%), Gaps = 28/172 (16%)
Query: 143 APASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAP 202
A A+ P P LA A APA A AAP A A APA APA A APA A AAP+ +
Sbjct: 511 AAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQ 570
Query: 203 APAPAPAPAPAPAPDAAPQESAEQ--GANQGQRGQEPL-ADQLHSGISGRPAAGT----- 254
P+ A P P A P + A Q + G L A + + G A G+
Sbjct: 571 KPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPV 630
Query: 255 --------AAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSP 298
A A +G+ ++ GPL P+ G V A P+P
Sbjct: 631 QAPGSGAPAPAGISGSDLQSSGGPL------------PDARPGAVQASSPAP 670
Score = 34.7 bits (78), Expect = 0.11
Identities = 35/145 (24%), Positives = 55/145 (37%), Gaps = 7/145 (4%)
Query: 162 PAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQ 221
P ++ + P +V+ L+ P P PV + P P ++ +
Sbjct: 419 PGKMSHSSSGPASVSQLSSWKTPEQ-----PDPVWVQSSVSGKGEKHPPPRTQLPSSSGK 473
Query: 222 ESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKR 281
S+ Q G PL S + AA AAA+A AA P ++ A
Sbjct: 474 ISSGNSFPPQQAGS-PLKRPF-SAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALA 531
Query: 282 SAPEKSSGDVPAPCPSPSAAPGVGS 306
+A + AP P+P+AAP V +
Sbjct: 532 AAAAPALAAAAAPAPAPAAAPAVAA 556
Score = 28.5 bits (62), Expect = 8.2
Identities = 21/63 (33%), Positives = 25/63 (39%), Gaps = 3/63 (4%)
Query: 103 LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPE---QLPSVPVPAPASTPPPVPVLAPAPA 159
LL P + P +PA SL G + P+ QLPSV PP L P
Sbjct: 744 LLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQLQPQWQ 803
Query: 160 PAP 162
P P
Sbjct: 804 PKP 806
>gi|19111150 angiomotin isoform 2 [Homo sapiens]
Length = 675
Score = 77.8 bits (190), Expect = 1e-14
Identities = 48/115 (41%), Positives = 53/115 (46%), Gaps = 2/115 (1%)
Query: 103 LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVP--VPAPASTPPPVPVLAPAPAP 160
++A PVAVA A +P A A P+ +PA AS V A A
Sbjct: 498 MVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAA 557
Query: 161 APAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 215
A VA APV L P PAPA A A APA AP APA AP PAP P PA
Sbjct: 558 AAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPA 612
Score = 76.3 bits (186), Expect = 3e-14
Identities = 57/143 (39%), Positives = 64/143 (44%), Gaps = 26/143 (18%)
Query: 106 PRPVAVAVAVSPPLEPAAE-SLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPA- 163
P PVA A + AA + + AP + + PA A+ P P A A A +PA
Sbjct: 475 PAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAA 534
Query: 164 ----PVAAPVA------------APVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPA---- 203
P AA VA A V VA APAP PAPA P PAP AA A APA
Sbjct: 535 AGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQA 594
Query: 204 ----PAPAPAPAPAPAPDAAPQE 222
PA AP PAP P P A E
Sbjct: 595 PTSAPAVAPTPAPTPTPAVAQAE 617
Score = 67.8 bits (164), Expect = 1e-11
Identities = 61/208 (29%), Positives = 76/208 (36%), Gaps = 41/208 (19%)
Query: 134 EQLPSVPVPAPASTP---------------------PPVPVLAPAPAPAPAPVAAPVAAP 172
E +PS P P P STP A AP PAPVAA A
Sbjct: 426 EYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAA 485
Query: 173 VAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQ 232
A A A AP A AA APA A AP+PA A A A +P +
Sbjct: 486 AITATAATITTTMVAAAPV-AVAAAAAPAAAAAPSPATAAATAAAVSPAAA--------- 535
Query: 233 RGQEPLADQLHSGISGRPAAGTAA---------ASANGAAIKKLSGPLISDFFAKRKRSA 283
GQ P A + S + P+A AA A A+ + P + A + A
Sbjct: 536 -GQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQA 594
Query: 284 PEKSSGDVPAPCPSPSAAPGVGSVEQTP 311
P + P P P+P+ A V +P
Sbjct: 595 PTSAPAVAPTPAPTPTPAVAQAEVPASP 622
Score = 61.2 bits (147), Expect = 1e-09
Identities = 56/192 (29%), Positives = 78/192 (40%), Gaps = 17/192 (8%)
Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAP 164
A P++V V+ AA + + + PV A+ P A AP+PA A
Sbjct: 468 AVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAA---APAAAAAPSPATAA 524
Query: 165 VAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESA 224
A +P A + A + A A A AP+ AA A APA APAP PAPA P +A
Sbjct: 525 ATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPA-APAPVPAPALVPVPAPAA 583
Query: 225 EQGANQGQRGQEPLADQLHSGISGRPAAGTA-----AASANGAAIKKLSGPLISDFFAKR 279
Q + Q A + + P A A+ A G +LS P ++
Sbjct: 584 AQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLT------ 637
Query: 280 KRSAPEKSSGDV 291
P+K+ G V
Sbjct: 638 --CNPDKTDGPV 647
>gi|166064029 angiomotin isoform 1 [Homo sapiens]
Length = 1084
Score = 77.8 bits (190), Expect = 1e-14
Identities = 48/115 (41%), Positives = 53/115 (46%), Gaps = 2/115 (1%)
Query: 103 LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVP--VPAPASTPPPVPVLAPAPAP 160
++A PVAVA A +P A A P+ +PA AS V A A
Sbjct: 907 MVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAA 966
Query: 161 APAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 215
A VA APV L P PAPA A A APA AP APA AP PAP P PA
Sbjct: 967 AAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPA 1021
Score = 76.3 bits (186), Expect = 3e-14
Identities = 57/143 (39%), Positives = 64/143 (44%), Gaps = 26/143 (18%)
Query: 106 PRPVAVAVAVSPPLEPAAE-SLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPA- 163
P PVA A + AA + + AP + + PA A+ P P A A A +PA
Sbjct: 884 PAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAA 943
Query: 164 ----PVAAPVA------------APVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPA---- 203
P AA VA A V VA APAP PAPA P PAP AA A APA
Sbjct: 944 AGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQA 1003
Query: 204 ----PAPAPAPAPAPAPDAAPQE 222
PA AP PAP P P A E
Sbjct: 1004 PTSAPAVAPTPAPTPTPAVAQAE 1026
Score = 67.8 bits (164), Expect = 1e-11
Identities = 61/208 (29%), Positives = 76/208 (36%), Gaps = 41/208 (19%)
Query: 134 EQLPSVPVPAPASTP---------------------PPVPVLAPAPAPAPAPVAAPVAAP 172
E +PS P P P STP A AP PAPVAA A
Sbjct: 835 EYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAA 894
Query: 173 VAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQ 232
A A A AP A AA APA A AP+PA A A A +P +
Sbjct: 895 AITATAATITTTMVAAAPV-AVAAAAAPAAAAAPSPATAAATAAAVSPAAA--------- 944
Query: 233 RGQEPLADQLHSGISGRPAAGTAA---------ASANGAAIKKLSGPLISDFFAKRKRSA 283
GQ P A + S + P+A AA A A+ + P + A + A
Sbjct: 945 -GQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQA 1003
Query: 284 PEKSSGDVPAPCPSPSAAPGVGSVEQTP 311
P + P P P+P+ A V +P
Sbjct: 1004 PTSAPAVAPTPAPTPTPAVAQAEVPASP 1031
Score = 61.2 bits (147), Expect = 1e-09
Identities = 56/192 (29%), Positives = 78/192 (40%), Gaps = 17/192 (8%)
Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAP 164
A P++V V+ AA + + + PV A+ P A AP+PA A
Sbjct: 877 AVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAA---APAAAAAPSPATAA 933
Query: 165 VAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESA 224
A +P A + A + A A A AP+ AA A APA APAP PAPA P +A
Sbjct: 934 ATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPA-APAPVPAPALVPVPAPAA 992
Query: 225 EQGANQGQRGQEPLADQLHSGISGRPAAGTA-----AASANGAAIKKLSGPLISDFFAKR 279
Q + Q A + + P A A+ A G +LS P ++
Sbjct: 993 AQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLT------ 1046
Query: 280 KRSAPEKSSGDV 291
P+K+ G V
Sbjct: 1047 --CNPDKTDGPV 1056
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 77.8 bits (190), Expect = 1e-14
Identities = 49/140 (35%), Positives = 59/140 (42%), Gaps = 25/140 (17%)
Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAP 164
AP P + SP L PAAE PAP + PPP P L P+P AP
Sbjct: 516 APTPGVPTGSPSPDLAPAAE-----------------PAPGAAPPPPPPLPGLPSPQEAP 558
Query: 165 VAAPVAAPVAVAVLAPAPAP------APAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDA 218
+AP AP P PAP P P P P P P P P P P P P PDA
Sbjct: 559 PSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDA 618
Query: 219 APQESAEQGANQGQRGQEPL 238
+ +E G G + ++P+
Sbjct: 619 LGRRDSELG--PGVKAKKPI 636
Score = 47.0 bits (110), Expect = 2e-05
Identities = 47/162 (29%), Positives = 59/162 (36%), Gaps = 6/162 (3%)
Query: 145 ASTPPPVPVLAPAPAPA-PAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPA 203
AS PP P AP AP P+ + V ++ P A + PVA P+
Sbjct: 455 ASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGG 514
Query: 204 PAPAP-APAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGA 262
AP P P +P+PD AP GA P L S P+A A G+
Sbjct: 515 DAPTPGVPTGSPSPDLAPAAEPAPGA---APPPPPPLPGLPSPQEAPPSAPPQAPPLPGS 571
Query: 263 AIKKLSGPLISDFFAKRKRSAPEK-SSGDVPAPCPSPSAAPG 303
+ PL D P + G VP P P P PG
Sbjct: 572 PEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPG 613
Score = 45.4 bits (106), Expect = 6e-05
Identities = 45/138 (32%), Positives = 57/138 (41%), Gaps = 14/138 (10%)
Query: 91 YRETVQVGRCRLLLAPRPVAVAVAVSPP-LEPAAESLDGLEEAPEQLPSVPVPAPASTPP 149
+ E+ +G R P A P LE E L+ E+ ++ P A +
Sbjct: 447 FSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELE--EKGLIRILRGPGDAVSIEIL 504
Query: 150 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPA---PAPAPAPVAAPAPAPAPAP 206
PV V P+ AP P P +P LAPA PAP P P P P P+P AP
Sbjct: 505 PVAVATPSGGDAPTP-GVPTGSPSPD--LAPAAEPAPGAAPPPPPPLP-GLPSPQEAPPS 560
Query: 207 APAPAP----APAPDAAP 220
AP AP +P P AP
Sbjct: 561 APPQAPPLPGSPEPPPAP 578
>gi|33286436 gametogenetin [Homo sapiens]
Length = 652
Score = 77.4 bits (189), Expect = 2e-14
Identities = 59/161 (36%), Positives = 74/161 (45%), Gaps = 9/161 (5%)
Query: 107 RPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVA 166
RP +A + PA + + + P L +P P P TPPP + PA P P PVA
Sbjct: 405 RPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELP-PLPPPTPPPT-LQPPALQPTPLPVA 462
Query: 167 APVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA----PAPAPAPDAAPQE 222
P+ + A AP APA PA A APAP+PAPAP A P APAP AAP +
Sbjct: 463 PPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIK 522
Query: 223 SAEQGANQGQRGQEPLA--DQLHSGISGRPAAGTAAASANG 261
+ + N+G R D LH A T S+ G
Sbjct: 523 TRTR-RNKGSRAARGATRKDGLHGDGPRERATATVPDSSGG 562
Score = 62.0 bits (149), Expect = 7e-10
Identities = 53/173 (30%), Positives = 67/173 (38%), Gaps = 14/173 (8%)
Query: 102 LLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAP----- 156
LL P + A P+ P L L P P + PA P P+PV P
Sbjct: 410 LLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGL 469
Query: 157 -----APAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA-- 209
A AP AP P A +PAPAP A P+P PV+APAPA AP
Sbjct: 470 GHKESALAPTAAPALPPALAADQAPAPSPAPAPTVA-EPSP-PVSAPAPAAAPIKTRTRR 527
Query: 210 PAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGA 262
+ A A ++ G +R + D G G A+ T AA+ A
Sbjct: 528 NKGSRAARGATRKDGLHGDGPRERATATVPDSSGGGGGGSGASQTGAANTRAA 580
Score = 43.5 bits (101), Expect = 2e-04
Identities = 59/217 (27%), Positives = 75/217 (34%), Gaps = 45/217 (20%)
Query: 123 AESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAP-------------- 168
AE DG E PS P + PPP P P V+AP
Sbjct: 312 AEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGG 371
Query: 169 -VAAP--VAVAVLAPAPAPAPAP----------APAPAPVAAPA---PAPAPAPAPAPAP 212
+ AP A A+ P +P P P PAPA +A P PAP P P
Sbjct: 372 GIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGP 431
Query: 213 ------APAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAA-GTAAASANGAAIK 265
P P P + + A Q P+A L G+ + +A AA A A+
Sbjct: 432 PGLQELPPLPPPTPPPTLQPPALQPT--PLPVAPPLTPGLGHKESALAPTAAPALPPALA 489
Query: 266 KLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAP 302
P A AP + P P+P+AAP
Sbjct: 490 ADQAP------APSPAPAPTVAEPSPPVSAPAPAAAP 520
Score = 43.1 bits (100), Expect = 3e-04
Identities = 67/255 (26%), Positives = 86/255 (33%), Gaps = 57/255 (22%)
Query: 108 PVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVP--VLAPAPAPAPAPV 165
P + V P P+ L LE +P A S PPP P L P P+ P
Sbjct: 57 PPGLMVPREPQASPSTLPLT-LERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPA 115
Query: 166 AAPV--------------AAPVAVAVLAPAPAP-----------APAPAPAPAPVAAPAP 200
PV P ++ L P P P AP+ P P P P
Sbjct: 116 GTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPP 175
Query: 201 APAPAPAPAP---APAPAPDAAPQESAEQG-ANQGQR------GQEPLADQ--------L 242
PA PA A A+P ++ G NQGQ G P A +
Sbjct: 176 PLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADS 235
Query: 243 HSGIS--------GRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAP 294
SG+S RP+ AAS++ AA L G FA + + P P
Sbjct: 236 ESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLP 295
Query: 295 CPSPSAAPGVGSVEQ 309
P AA +G V +
Sbjct: 296 ---PGAARPLGEVSR 307
Score = 37.7 bits (86), Expect = 0.013
Identities = 21/69 (30%), Positives = 28/69 (40%)
Query: 144 PASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPA 203
P S PP ++ P +P+ + + P V A AP PAPA P P+
Sbjct: 52 PGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKW 111
Query: 204 PAPAPAPAP 212
PA P P
Sbjct: 112 QKPAGTPVP 120
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 77.0 bits (188), Expect = 2e-14
Identities = 55/157 (35%), Positives = 62/157 (39%), Gaps = 18/157 (11%)
Query: 112 AVAVSPPLEPAAESLDGLEEAPEQLPSV-----PVPAPASTPPPVPVLAPAPAPAPAPVA 166
A V PP A AP P+ P P PA PPP PV A APA AP A
Sbjct: 96 AARVQPPRRGATPPAP--PRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAA 153
Query: 167 APVAAPVAVAVLAP-----------APAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 215
A AP + P AP PAPA PA AP A P AP PA A P P
Sbjct: 154 AAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPP 213
Query: 216 PDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAA 252
P P +Q Q P + +G + RP +
Sbjct: 214 PPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVS 250
Score = 67.8 bits (164), Expect = 1e-11
Identities = 51/153 (33%), Positives = 57/153 (37%), Gaps = 31/153 (20%)
Query: 159 APAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDA 218
A PAP AP AP A A AP P PAP P PAP AAPA AP A A A AP A
Sbjct: 106 ATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPA 165
Query: 219 APQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAK 278
P A++ A P A A A A+ +GP
Sbjct: 166 QPGPRAQRAA---------------------PLAAPPPAPAAPPAVAPPAGP-------- 196
Query: 279 RKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTP 311
R AP + P P P P +Q P
Sbjct: 197 --RRAPPPAVAAREPPLPPPPQPPAPPQQQQPP 227
Score = 65.9 bits (159), Expect = 5e-11
Identities = 47/124 (37%), Positives = 50/124 (40%), Gaps = 12/124 (9%)
Query: 105 APR--PVAVAVAVSPPLE-----PAAESLDGLEEAPEQLPSV----PVPAPASTPPPVPV 153
APR P A A A PP PA + AP + P P PA P
Sbjct: 114 APRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQR 173
Query: 154 LAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPA 213
AP AP PAP A P AP A AP PA A P P P PAP P P P P
Sbjct: 174 AAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPP-PQPQ 232
Query: 214 PAPD 217
P P+
Sbjct: 233 PPPE 236
Score = 31.2 bits (69), Expect = 1.3
Identities = 24/74 (32%), Positives = 26/74 (35%), Gaps = 5/74 (6%)
Query: 99 RCRLLLAPRPVAVAV-AVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPA 157
R L AP P A AV+PP P + LP P P PP P
Sbjct: 173 RAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLP----PPPQPPAPPQQQQPPP 228
Query: 158 PAPAPAPVAAPVAA 171
P P P P V A
Sbjct: 229 PQPQPPPEGGAVRA 242
>gi|4757962 cyclin-dependent kinase inhibitor 1B [Homo sapiens]
Length = 198
Score = 75.1 bits (183), Expect = 8e-14
Identities = 45/118 (38%), Positives = 60/118 (50%), Gaps = 19/118 (16%)
Query: 26 RTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPLRGPGRLQWTEVDSD 85
+ SACR+LFGPVDHEEL+R+L+ ++ Q +W++DFQ PL G+ +W EV+
Sbjct: 25 KPSACRNLFGPVDHEELTRDLEKHCRDMEEASQRKWNFDFQNHKPLE--GKYEWQEVEKG 82
Query: 86 SVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPA 143
S+P FY PRP A V PA ES D P P + PA
Sbjct: 83 SLPEFYYR-----------PPRPPKGACKV-----PAQESQDVSGSRP-AAPLIGAPA 123
>gi|24307909 ral guanine nucleotide dissociation stimulator isoform
1 [Homo sapiens]
Length = 914
Score = 73.6 bits (179), Expect = 2e-13
Identities = 53/134 (39%), Positives = 62/134 (46%), Gaps = 22/134 (16%)
Query: 124 ESLDGLEEAPEQLPSVPVPAP------ASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAV 177
E + +E PE L VP P A TP P +P PAPAP P AP AP +
Sbjct: 249 EHSEPIEAEPEALSPVPALKPTPELELALTPARAP--SPVPAPAPEPEPAPTPAPGSELE 306
Query: 178 LAPAPAP----APAPA----PAPAPVAAPAPAPAPAPAPA------PAPAPAPDAAPQES 223
+APAPAP AP PA APAP PAP PAP+ PAPAP P P
Sbjct: 307 VAPAPAPELQQAPEPAVGLESAPAPALELEPAPEQDPAPSQTLELEPAPAPVPSLQPSWP 366
Query: 224 AEQGANQGQRGQEP 237
+ A G ++P
Sbjct: 367 SPVVAENGLSEEKP 380
Score = 54.3 bits (129), Expect = 1e-07
Identities = 48/147 (32%), Positives = 59/147 (40%), Gaps = 44/147 (29%)
Query: 164 PVAAPVAAPVAVAVLAPAPAP--APAPAPAPAPVAAPAPAPAPAPAPAP------APAPA 215
P+ A A V L P P A PA AP+PV APAP P PAP PAP APAPA
Sbjct: 253 PIEAEPEALSPVPALKPTPELELALTPARAPSPVPAPAPEPEPAPTPAPGSELEVAPAPA 312
Query: 216 PDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDF 275
P+ Q++ E PA G +A A ++
Sbjct: 313 PEL--QQAPE------------------------PAVGLESAPAPALELEP--------- 337
Query: 276 FAKRKRSAPEKSSGDVPAPCPSPSAAP 302
A + AP ++ PAP P PS P
Sbjct: 338 -APEQDPAPSQTLELEPAPAPVPSLQP 363
Score = 47.4 bits (111), Expect = 2e-05
Identities = 39/99 (39%), Positives = 44/99 (44%), Gaps = 15/99 (15%)
Query: 105 APRPVAVAVAVSPPLEPAAESLDG--LEEAPEQLPSV---PVPAPASTPPPVPVLAPAPA 159
AP PV A +P EPA G LE AP P + P PA P P L PA
Sbjct: 282 APSPVP---APAPEPEPAPTPAPGSELEVAPAPAPELQQAPEPAVGLESAPAPALELEPA 338
Query: 160 PAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA-PAPVAA 197
P P AP L PAPAP P+ P+ P+PV A
Sbjct: 339 PEQDP------APSQTLELEPAPAPVPSLQPSWPSPVVA 371
>gi|108796058 ral guanine nucleotide dissociation stimulator isoform
2 [Homo sapiens]
Length = 859
Score = 73.6 bits (179), Expect = 2e-13
Identities = 53/134 (39%), Positives = 62/134 (46%), Gaps = 22/134 (16%)
Query: 124 ESLDGLEEAPEQLPSVPVPAP------ASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAV 177
E + +E PE L VP P A TP P +P PAPAP P AP AP +
Sbjct: 194 EHSEPIEAEPEALSPVPALKPTPELELALTPARAP--SPVPAPAPEPEPAPTPAPGSELE 251
Query: 178 LAPAPAP----APAPA----PAPAPVAAPAPAPAPAPAPA------PAPAPAPDAAPQES 223
+APAPAP AP PA APAP PAP PAP+ PAPAP P P
Sbjct: 252 VAPAPAPELQQAPEPAVGLESAPAPALELEPAPEQDPAPSQTLELEPAPAPVPSLQPSWP 311
Query: 224 AEQGANQGQRGQEP 237
+ A G ++P
Sbjct: 312 SPVVAENGLSEEKP 325
Score = 54.3 bits (129), Expect = 1e-07
Identities = 48/147 (32%), Positives = 59/147 (40%), Gaps = 44/147 (29%)
Query: 164 PVAAPVAAPVAVAVLAPAPAP--APAPAPAPAPVAAPAPAPAPAPAPAP------APAPA 215
P+ A A V L P P A PA AP+PV APAP P PAP PAP APAPA
Sbjct: 198 PIEAEPEALSPVPALKPTPELELALTPARAPSPVPAPAPEPEPAPTPAPGSELEVAPAPA 257
Query: 216 PDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDF 275
P+ Q++ E PA G +A A ++
Sbjct: 258 PEL--QQAPE------------------------PAVGLESAPAPALELEP--------- 282
Query: 276 FAKRKRSAPEKSSGDVPAPCPSPSAAP 302
A + AP ++ PAP P PS P
Sbjct: 283 -APEQDPAPSQTLELEPAPAPVPSLQP 308
Score = 47.4 bits (111), Expect = 2e-05
Identities = 39/99 (39%), Positives = 44/99 (44%), Gaps = 15/99 (15%)
Query: 105 APRPVAVAVAVSPPLEPAAESLDG--LEEAPEQLPSV---PVPAPASTPPPVPVLAPAPA 159
AP PV A +P EPA G LE AP P + P PA P P L PA
Sbjct: 227 APSPVP---APAPEPEPAPTPAPGSELEVAPAPAPELQQAPEPAVGLESAPAPALELEPA 283
Query: 160 PAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA-PAPVAA 197
P P AP L PAPAP P+ P+ P+PV A
Sbjct: 284 PEQDP------APSQTLELEPAPAPVPSLQPSWPSPVVA 316
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 72.0 bits (175), Expect = 6e-13
Identities = 58/151 (38%), Positives = 68/151 (45%), Gaps = 36/151 (23%)
Query: 102 LLLAPRPV-------AVAVAVSPPLEPAAESLDGLEEAPEQLPS-VPVPAPAS------- 146
LLLAP VA A SP L PA+ AP P+ + APAS
Sbjct: 1525 LLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALA 1584
Query: 147 TP------PPVPVLAPAPAP--APAPVAAPV--AAPVAVAVLAPAPAPAP---------- 186
TP P +LAP+PAP AP PV AP AAPV + P P AP
Sbjct: 1585 TPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLAS 1644
Query: 187 -APAPAPAPVAAPAPAPAPAPAPAPAPAPAP 216
+P PAP PV AP+ PAP P+P P+P
Sbjct: 1645 ASPVPAPTPVLAPSSTQTMLPAPVPSPLPSP 1675
Score = 66.6 bits (161), Expect = 3e-11
Identities = 32/84 (38%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 130 EEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPA 189
E P P P P PAS P +P L P P AP P++AP + + P+P P
Sbjct: 2434 ERVPRPAPR-PRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIP 2492
Query: 190 PAPAPVAAPAPAPAPAPAPAPAPA 213
P +P P PA P PA P PA
Sbjct: 2493 PCSSPACTPPPACTPPPAHTPPPA 2516
Score = 65.1 bits (157), Expect = 8e-11
Identities = 65/246 (26%), Positives = 95/246 (38%), Gaps = 29/246 (11%)
Query: 70 PLRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGL 129
P PGRL + + P T + R L L P A +P P S
Sbjct: 1346 PTLTPGRLPTPTLGTARAPM---PTPTLVRPLLKLVHSPSPEVSASAPGAAPLTIS---- 1398
Query: 130 EEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPA 189
+P +PS +P PAS+P P+P +P +P + V+ P+++ + ++V P PA
Sbjct: 1399 --SPLHVPS-SLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISV------PTTLPA 1449
Query: 190 PAPAPVAAPAPAPAPAPAPAPA--PAPAPDAAPQESAEQG-ANQGQRGQEPLADQLHSGI 246
PA AP+ P AP A PA + P AP A G + G P A L G+
Sbjct: 1450 PASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGL 1509
Query: 247 SGRPAAGT----------AAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCP 296
+ P+ + A S++ + P S A S PAP
Sbjct: 1510 ATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQ 1569
Query: 297 SPSAAP 302
+ AP
Sbjct: 1570 ASLLAP 1575
Score = 61.6 bits (148), Expect = 9e-10
Identities = 57/194 (29%), Positives = 76/194 (39%), Gaps = 28/194 (14%)
Query: 117 PPLEPAAESLDGLEEAPEQLPSVPVPAPASTPP--PVPVLAPAPAPAPAPVAAPVAAPVA 174
PPL PA LP+V P P TP P P L A AP P P + P+
Sbjct: 1325 PPLAPAPRP------PSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPT---LVRPLL 1375
Query: 175 VAVLAPAP-APAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQR 233
V +P+P A AP AP +++P P+ P PA +P P P+++P S
Sbjct: 1376 KLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSST----- 1430
Query: 234 GQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPA 293
PL+ L + T A A+ +S PL S P + P
Sbjct: 1431 VSVPLSSSLPISV-----PTTLPAPASAPLTIPISAPLTV------SASGPALLTSVTPP 1479
Query: 294 PCPSPSAAPGVGSV 307
P AAPG S+
Sbjct: 1480 LAPVVPAAPGPPSL 1493
Score = 58.5 bits (140), Expect = 7e-09
Identities = 43/130 (33%), Positives = 48/130 (36%), Gaps = 15/130 (11%)
Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAP----EQLPSVPVPAPASTPPPVPVLAPAPAP 160
A P VS L A G P Q S P P +P V PAP P
Sbjct: 2385 AKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTP-PRCSPARERVPRPAPRP 2443
Query: 161 APAPVAAPVAAPVAVAVLAPAPAPAPAP----------APAPAPVAAPAPAPAPAPAPAP 210
P P +AP A P V V AP P AP P+P P + P +PA P P
Sbjct: 2444 RPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPP 2503
Query: 211 APAPAPDAAP 220
A P P P
Sbjct: 2504 ACTPPPAHTP 2513
Score = 58.5 bits (140), Expect = 7e-09
Identities = 36/84 (42%), Positives = 42/84 (50%), Gaps = 12/84 (14%)
Query: 141 VPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAP--------APAPAPAPAP 192
VP PA P P P APA PA PV PV+APV ++ AP P P+P P
Sbjct: 2436 VPRPAPRPRPTPASAPAAIPALVPV--PVSAPVPIS--APNPITILPVHILPSPPPPSQI 2491
Query: 193 APVAAPAPAPAPAPAPAPAPAPAP 216
P ++PA P PA P PA P P
Sbjct: 2492 PPCSSPACTPPPACTPPPAHTPPP 2515
Score = 55.1 bits (131), Expect = 8e-08
Identities = 71/265 (26%), Positives = 86/265 (32%), Gaps = 77/265 (29%)
Query: 103 LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPS---VPVPAPASTP----------- 148
+ AP+ +A + +PPL P AP S VPV AP+STP
Sbjct: 1590 MAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVP 1649
Query: 149 PPVPVLAPAPAPA--PAPVAAPVAAPVAVAVLAPAPAPAP-------------------- 186
P PVLAP+ PAPV +P+ +P + LA APA AP
Sbjct: 1650 APTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQG 1709
Query: 187 -------------------------APAPAPAPVA----APAPAPAPAPAPAPAPAPAPD 217
AP P P APAP APA PAPA
Sbjct: 1710 PFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLT 1769
Query: 218 AAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFA 277
AP S+ L + P G AAA A P A
Sbjct: 1770 LAPASSSASLLAPAS------VQTLTLSPAPVPTLGPAAAQTLALAPASTQSP------A 1817
Query: 278 KRKRSAPEKSSGDVPAPCPSPSAAP 302
+ S +SG P P S P
Sbjct: 1818 SQASSLVVSASGAAPLPVTMVSRLP 1842
Score = 53.9 bits (128), Expect = 2e-07
Identities = 65/229 (28%), Positives = 79/229 (34%), Gaps = 60/229 (26%)
Query: 110 AVAVAVSPPLEPAAESLDGLEEAPEQLPS-------------VPVPAPASTPPPVPVLAP 156
A+ +V+PPL P + G P PS P+ +S+ P L
Sbjct: 1471 ALLTSVTPPLAPVVPAAPG---PPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLL 1527
Query: 157 APAPAPAPVAAPVAAPVAVAVLAPAPAPA-PAP-APAPAPVAAPAPAPAP---------- 204
AP + P AP VL PA A A P P AP PAP A APA
Sbjct: 1528 APTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPL 1587
Query: 205 -----------APAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAG 253
AP+PAP AP P AP A Q +A S P
Sbjct: 1588 APMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAP------SSTPGTS 1641
Query: 254 TAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAP 302
A+AS A L AP + +PAP PSP +P
Sbjct: 1642 LASASPVPAPTPVL---------------APSSTQTMLPAPVPSPLPSP 1675
Score = 52.0 bits (123), Expect = 7e-07
Identities = 33/109 (30%), Positives = 44/109 (40%), Gaps = 4/109 (3%)
Query: 106 PRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPV 165
PRP V + V+ L+P + +G P P+ PPP P L+ P P P P
Sbjct: 985 PRPKPVKMKVNRMLQPVPKQ-EGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQ 1043
Query: 166 AAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAP 214
P + V+ + P PA P P PV P P P P+P
Sbjct: 1044 VLPASLMVSASPAGPPLIPASRP---PGPVLLPPLQPNSGSLPQVLPSP 1089
Score = 51.6 bits (122), Expect = 9e-07
Identities = 53/176 (30%), Positives = 68/176 (38%), Gaps = 30/176 (17%)
Query: 141 VPAPAST------PP--PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAP 192
VP PA T PP P L+ APAP AP + AP LAPA + A APA
Sbjct: 1725 VPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPAS 1784
Query: 193 APVAAPAPAPAPAPAPAPAPAPA-PDAAPQESAEQGAN--QGQRGQEPLADQLHSGI--- 246
+PAP P PA A A A+ Q A Q ++ G PL + S +
Sbjct: 1785 VQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVS 1844
Query: 247 ----------SGRPAAGTAAASANGAAIKKLSGP------LISDFFAKRKRSAPEK 286
SG P+ + A S G ++ P + KRKR E+
Sbjct: 1845 KDEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPPRSPFYLDSLEEKRKRQRSER 1900
Score = 51.2 bits (121), Expect = 1e-06
Identities = 55/180 (30%), Positives = 69/180 (38%), Gaps = 30/180 (16%)
Query: 66 QQDMPLRGPGRLQWTEVDSDS-VPAFYRETVQVGRCRLLLAPRPVAV-------AVAVSP 117
Q +P+ P T + S S VPA +L AP P + +A++P
Sbjct: 1626 QTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAP 1685
Query: 118 PLEPAAESLDGLEEAPEQL-------PSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVA 170
L P +L G +P Q P P P + P L P PA + P
Sbjct: 1686 ALAP---TLGG--SSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPL 1740
Query: 171 APVAVAVLAPAPAPAPA----PAPAPAPVAAPAPAPAPAPAPAP------APAPAPDAAP 220
P LAPAP APA PAPA APA + A APA +PAP P P
Sbjct: 1741 GPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGP 1800
Score = 48.9 bits (115), Expect = 6e-06
Identities = 37/116 (31%), Positives = 49/116 (42%), Gaps = 10/116 (8%)
Query: 102 LLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPA 161
L+ A RP + PPL+P + SL P+ LPS ++ PP P L+ P P
Sbjct: 1060 LIPASRPPGPVLL--PPLQPNSGSL------PQVLPSPLGVLSGTSRPPTPTLSLKPTP- 1110
Query: 162 PAPVA-APVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAP 216
PAPV +P P + ++L P P P A PAP PAP
Sbjct: 1111 PAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAP 1166
Score = 45.1 bits (105), Expect = 8e-05
Identities = 38/153 (24%), Positives = 53/153 (34%), Gaps = 5/153 (3%)
Query: 117 PPLEPAAESLDGLEEAPEQLP-SVPVPAPASTP----PPVPVLAPAPAPAPAPVAAPVAA 171
P PA E + P P S P PA P PVP+ AP P P
Sbjct: 2427 PRCSPARERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPP 2486
Query: 172 PVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQG 231
P + +PA P PA P P P PA P+ P + P ++ G
Sbjct: 2487 PPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLG 2546
Query: 232 QRGQEPLADQLHSGISGRPAAGTAAASANGAAI 264
R + L Q + A A++ + ++
Sbjct: 2547 LRPEAELCAQALASPESLELASVASSETSSLSL 2579
Score = 43.9 bits (102), Expect = 2e-04
Identities = 41/127 (32%), Positives = 50/127 (39%), Gaps = 18/127 (14%)
Query: 104 LAPR-PVAVAVAVSPPLEPAAESLDGLEEAPEQ-LPSVPVPAPASTPPPVPVLAPAPAPA 161
LAP PV A A + L PA+ S L A Q L P P P P LA APA
Sbjct: 1754 LAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPAST 1813
Query: 162 PAP--------VAAPVAAPVAVAVLAPAPAPAPAP--------APAPAPVAAPAPAPAPA 205
+P V+A AAP+ V +++ P P P+P A P P
Sbjct: 1814 QSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPR 1873
Query: 206 PAPAPAP 212
P P P
Sbjct: 1874 RQPPPPP 1880
Score = 40.0 bits (92), Expect = 0.003
Identities = 39/131 (29%), Positives = 51/131 (38%), Gaps = 13/131 (9%)
Query: 106 PRPVAVAVAVSPPLEPAAESLDGLEEAPEQLP-SVPVPAPASTPPPVPVLAP-----APA 159
PR V V PP P + P+ LP S+ V A + PP +P P P
Sbjct: 1015 PRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPP 1074
Query: 160 PAPAPVAAPVAAPVAVAVLA-----PAPAPAPAPAPAPAPV-AAPAPAPAPAPAPAPAPA 213
P + P P + VL+ P P + P P PAPV +PAP P + P
Sbjct: 1075 LQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTP-PAPVRLSPAPPPGSSSLLKPLTV 1133
Query: 214 PAPDAAPQESA 224
P P +A
Sbjct: 1134 PPGYTFPPAAA 1144
Score = 35.0 bits (79), Expect = 0.087
Identities = 48/211 (22%), Positives = 73/211 (34%), Gaps = 34/211 (16%)
Query: 120 EPAAESLDG--LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAV 177
+ A +S +G L PE +P+ S +P A + P P+ A +
Sbjct: 2622 QEAPDSAEGTTLTVLPEG-EELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEA 2680
Query: 178 LAPAPAPAPAPAPAPAPVAAPAPAPAPAPAP-APAPAPAPDAAPQESAE-QGANQGQRGQ 235
P +P A VAAP+ + + +P P+PA P E +G G+ GQ
Sbjct: 2681 KTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQ 2740
Query: 236 EPLADQLHSGISGR-------------------------PAAGTAAASANGAAIKKLSGP 270
P L + GR P +AS +++ +SGP
Sbjct: 2741 PPGPKVLRK-LPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGP 2799
Query: 271 LISDFFAKRKRSAPEKSSGDVPAPCPSPSAA 301
S +AP S +P P P A
Sbjct: 2800 ESSPPIGGPCEAAP---SSSLPTPPQQPFIA 2827
Score = 35.0 bits (79), Expect = 0.087
Identities = 51/209 (24%), Positives = 64/209 (30%), Gaps = 42/209 (20%)
Query: 103 LLAPRPVAVAVAVSPPLEPAAESLD---GLEEAPEQL------PSVPVPAPASTPPPVPV 153
LLA P AV P + D G++EAP + PVP P + PV
Sbjct: 2848 LLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPV 2907
Query: 154 LAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPA 213
L P P P P+ P P P P +PV P P P
Sbjct: 2908 LEPQLIPGPQPL---------------GPQPVHRPNPLLSPVEKRRRGRPPKARDLPIPG 2952
Query: 214 PAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLIS 273
A N R Q P + + TA + + + P
Sbjct: 2953 TISSAG-------DGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSP--- 3002
Query: 274 DFFAKRKRSAPEKSSGDVPAPCPSPSAAP 302
KRKR P K+ P P PS P
Sbjct: 3003 ---PKRKRGRPPKN-----PPSPRPSQLP 3023
Score = 32.7 bits (73), Expect = 0.43
Identities = 54/257 (21%), Positives = 84/257 (32%), Gaps = 50/257 (19%)
Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVP--VLAPAPAPAP 162
AP P+ + P P + P P PA TPPP ++ P+
Sbjct: 2470 APNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLL 2529
Query: 163 APVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPD----- 217
P + P++A V L P +P + + A + + + P D
Sbjct: 2530 GPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVA 2589
Query: 218 ---------------AAPQESAEQGANQGQRGQE-------------------PLADQLH 243
+AP + E G+ + QE PL
Sbjct: 2590 VEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSES 2649
Query: 244 SGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKS----SGDVPAPCPSPS 299
+G+ P+A + + S L AK S+PEK + +V AP S S
Sbjct: 2650 NGLELPPSAASDEPLQEPLEADRTSEELTE---AKTPTSSPEKPQELVTAEVAAPSTSSS 2706
Query: 300 A--APGVGSVEQTPRKR 314
A +P S + PR+R
Sbjct: 2707 ATSSPEGPSPARPPRRR 2723
Score = 32.0 bits (71), Expect = 0.74
Identities = 25/89 (28%), Positives = 30/89 (33%), Gaps = 11/89 (12%)
Query: 143 APASTPPPVP---------VLAPAPAPAPAPVAAP--VAAPVAVAVLAPAPAPAPAPAPA 191
A A PPP P +L P P V AP+ + P P P + P
Sbjct: 978 ATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPT 1037
Query: 192 PAPVAAPAPAPAPAPAPAPAPAPAPDAAP 220
P PV PA A P P + P
Sbjct: 1038 PGPVPQVLPASLMVSASPAGPPLIPASRP 1066
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 72.0 bits (175), Expect = 6e-13
Identities = 52/132 (39%), Positives = 61/132 (46%), Gaps = 16/132 (12%)
Query: 108 PVAVAVAV-SPPLEPAAESLDG--------LEEAPEQLPS-VPVPAPASTPPPVPVLAPA 157
P+A A AV PP P S + LEE P P P P P PPP P P
Sbjct: 1423 PLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPP---PQ 1479
Query: 158 PA-PAPAPVAAPVAAPVAVAVLAPAPAPA-PAPAPAPAPVAAPAPAPAPAP-APAPAPAP 214
PA P+P P+ AP + L P P PA P+P P P P AAP AP P AP+P
Sbjct: 1480 PALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPE 1539
Query: 215 APDAAPQESAEQ 226
PD P A++
Sbjct: 1540 LPDTRPLHLAKK 1551
Score = 71.6 bits (174), Expect = 8e-13
Identities = 50/124 (40%), Positives = 57/124 (45%), Gaps = 11/124 (8%)
Query: 106 PRPVAVAVAVSPPLE--PAAESLDGLEEAP--EQLPSVPVPAPASTPPPVPVLAPAPAPA 161
P A AV PPL P+A S +G E P E+ P P P PA TP P P P P
Sbjct: 1423 PLAPAAAVPGPPPLPGLPSANS-NGTPEPPLLEEKPP-PTPPPAPTPQPQP-----PPPP 1475
Query: 162 PAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQ 221
P P A + P VA +P P P P P P + +P P P PA AP AP P A
Sbjct: 1476 PPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSP 1535
Query: 222 ESAE 225
E E
Sbjct: 1536 EDPE 1539
Score = 70.5 bits (171), Expect = 2e-12
Identities = 45/113 (39%), Positives = 51/113 (45%), Gaps = 13/113 (11%)
Query: 117 PPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLA----PAPAPAPAPVAAPVAAP 172
PPL PAA P LP +P TP P P+L P P PAP P P P
Sbjct: 1422 PPLAPAAAV-----PGPPPLPGLPSANSNGTPEP-PLLEEKPPPTPPPAPTPQPQPPPPP 1475
Query: 173 VAVAVLAPAPAPAPAPAPA---PAPVAAPAPAPAPAPAPAPAPAPAPDAAPQE 222
P+P P AP P+ P P+ P P P+P P P PA AP AAP E
Sbjct: 1476 PPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPE 1528
Score = 54.3 bits (129), Expect = 1e-07
Identities = 38/105 (36%), Positives = 46/105 (43%), Gaps = 14/105 (13%)
Query: 127 DGLEEAPEQLPSVPVPAPASTPPPV-PVLAPAPA-PAPAPVAAPVAA--------PVAVA 176
+ + A L P+ P T P P LAPA A P P P+ +A P+
Sbjct: 1396 ESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEE 1455
Query: 177 VLAPAPAPAPAPAPAPAPVAAPAPAPAPA-PAPAPAPAPAPDAAP 220
P P PAP P P P P P P P PA P+P P AP P + P
Sbjct: 1456 KPPPTPPPAPTPQPQPPP---PPPPPQPALPSPPPLVAPTPSSPP 1497
Score = 47.0 bits (110), Expect = 2e-05
Identities = 25/80 (31%), Positives = 31/80 (38%), Gaps = 6/80 (7%)
Query: 151 VPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPA------PVAAPAPAPAP 204
+ L P P + P P+A A P P P P A + P+ P P P
Sbjct: 1402 ISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTP 1461
Query: 205 APAPAPAPAPAPDAAPQESA 224
PAP P P P P P + A
Sbjct: 1462 PPAPTPQPQPPPPPPPPQPA 1481
Score = 45.8 bits (107), Expect = 5e-05
Identities = 39/128 (30%), Positives = 50/128 (39%), Gaps = 36/128 (28%)
Query: 147 TPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAP--------APAPAPAPAPAPV--- 195
+PPP P A + P P + P VL P P + AP+P+P+ + V
Sbjct: 763 SPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVH 822
Query: 196 --------AAPAPAPAPAPAPAPAP---------------APAPDAAPQESAE-QGANQG 231
AP P P P P P P P AP+P P+ES + GA Q
Sbjct: 823 LLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQE 882
Query: 232 QRGQ-EPL 238
G EPL
Sbjct: 883 LLGALEPL 890
Score = 45.4 bits (106), Expect = 6e-05
Identities = 33/96 (34%), Positives = 38/96 (39%), Gaps = 16/96 (16%)
Query: 137 PSVPVPAPASTP--PPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAP 194
P + P STP PP+ A P P P P P A + P P P P P
Sbjct: 1408 PPLAGPKDTSTPDGPPLAPAAAVPGPPPLP-----GLPSANSNGTPEP---PLLEEKPPP 1459
Query: 195 VAAPAPAPAPAPAPAP------APAPAPDAAPQESA 224
PAP P P P P P P+P P AP S+
Sbjct: 1460 TPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSS 1495
Score = 45.1 bits (105), Expect = 8e-05
Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 6/91 (6%)
Query: 129 LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAP 188
L+++P P P A ++ P P +L A P V P + +VL+ AP+P+P+
Sbjct: 760 LQKSP---PPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSA 816
Query: 189 APAPAPVAAPAP---APAPAPAPAPAPAPAP 216
+ + PA AP P P P P P P P
Sbjct: 817 SKVGVHLLEPATRDGAPQPPPPPPPPPPPMP 847
Score = 44.3 bits (103), Expect = 1e-04
Identities = 33/95 (34%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPA-PAPA 163
AP P PP +PA S P + P P+S PPP P PA P+P
Sbjct: 1464 APTPQPQPPPPPPPPQPALPSP----------PPLVAPTPSSPPPPPLPPPPPPAMPSPP 1513
Query: 164 PVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAP 198
P P AAP+A PA AP+P P P
Sbjct: 1514 PPPPPAAAPLAAPPEEPA---APSPEDPELPDTRP 1545
Score = 39.7 bits (91), Expect = 0.004
Identities = 53/201 (26%), Positives = 65/201 (32%), Gaps = 38/201 (18%)
Query: 106 PRPVAVAVAVS-PPLEPAAESL----DGLEEAPEQLPSVPV--------------PA--- 143
P PV ++++ PP P A L D L P Q P+VP PA
Sbjct: 161 PFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLG 220
Query: 144 PASTPPPVPVLAPAPAPAP---------------APVAAPVAAPVAVAVLAPAPAPAPAP 188
PA TPP P P P P P A AA ++P AP P P
Sbjct: 221 PAQTPPYRPG-PPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPE 279
Query: 189 APAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISG 248
P PA A P P P A + G+ + LA G
Sbjct: 280 RALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEP 339
Query: 249 RPAAGTAAASANGAAIKKLSG 269
P AG + + A SG
Sbjct: 340 SPGAGEPSKAGPSGATAGASG 360
Score = 39.7 bits (91), Expect = 0.004
Identities = 41/170 (24%), Positives = 56/170 (32%), Gaps = 15/170 (8%)
Query: 149 PPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAP 208
PPVPV A P A P APAP P P + P P A
Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPP------PKAPAPPPKPETPEKTTSEKPPEQTPETAM 1723
Query: 209 APAPAP-APDAAPQESAEQGANQGQRGQEPL-ADQLHSGISGRPAAGTAAASANGAAIKK 266
PAP P E+ + RG+ PL ++ SG RP A + + K
Sbjct: 1724 PEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPK 1783
Query: 267 LSGPLISDFFAKRKRSAPEK-------SSGDVPAPCPSPSAAPGVGSVEQ 309
+ +KR K + G P ++PG S ++
Sbjct: 1784 ARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSEDE 1833
Score = 37.0 bits (84), Expect = 0.023
Identities = 32/94 (34%), Positives = 36/94 (38%), Gaps = 32/94 (34%)
Query: 103 LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAP 162
L+AP P SPP P LP P PA S PPP P PA
Sbjct: 1488 LVAPTP------SSPP--------------PPPLPPPPPPAMPSPPPP-------PPPAA 1520
Query: 163 APVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVA 196
AP+AAP P AP+P P P +A
Sbjct: 1521 APLAAPPEEPA-----APSPEDPELPDTRPLHLA 1549
Score = 36.2 bits (82), Expect = 0.039
Identities = 41/131 (31%), Positives = 52/131 (39%), Gaps = 17/131 (12%)
Query: 108 PVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPA--------PA 159
P ++ A SP + + LE A P P P PPP+P+ A PA
Sbjct: 803 PSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPA 862
Query: 160 PAPAPVAAP---VAAPVAVAVLAPAPAPAPAPAPAPAPVAAP-APAPAPAPA---PAPAP 212
AP+P P + P A+ L A P P PAP V P + PA A P+P
Sbjct: 863 -APSPRLRPEESLDPPGAMQELLGALEPLP-PAPGDTGVGPPNSEGKDPAGAYRSPSPQG 920
Query: 213 APAPDAAPQES 223
AP P S
Sbjct: 921 TKAPRFVPLTS 931
Score = 32.7 bits (73), Expect = 0.43
Identities = 23/81 (28%), Positives = 30/81 (37%), Gaps = 2/81 (2%)
Query: 143 APASTPPPVPVLAPAP--APAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAP 200
A A PP P P P A A P + + P P+ A + +
Sbjct: 976 AGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPH 1035
Query: 201 APAPAPAPAPAPAPAPDAAPQ 221
AP P P P P PAP + P+
Sbjct: 1036 QAAPPPPPPPPPPPAPASEPK 1056
Score = 30.4 bits (67), Expect = 2.1
Identities = 29/101 (28%), Positives = 36/101 (35%), Gaps = 20/101 (19%)
Query: 159 APAPAPVAAPVAAPVAVAVLAPAPAP-APAPAPAPAPVAAPAP-APAPAPAP-------- 208
+P P P A P +L A P P P P P P+ + AP+P+P
Sbjct: 763 SPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVH 822
Query: 209 ---------APAPAPAPDAAPQESAEQ-GANQGQRGQEPLA 239
AP P P P P Q A+ G EP A
Sbjct: 823 LLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAA 863
Score = 29.3 bits (64), Expect = 4.8
Identities = 32/107 (29%), Positives = 39/107 (36%), Gaps = 23/107 (21%)
Query: 146 STPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAP-----------------APAP 188
S P PVP P +P A + +P V L P+ AP PA
Sbjct: 159 SRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAG 218
Query: 189 -APAPAPVAAPAPAPAPAPAPAPAPAP----APDAAPQESAEQGANQ 230
PA P P P P P P P P A +A +AEQ + Q
Sbjct: 219 LGPAQTPPYRPGP-PDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQ 264
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 71.6 bits (174), Expect = 8e-13
Identities = 75/215 (34%), Positives = 86/215 (40%), Gaps = 29/215 (13%)
Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVP----APASTPPPVPVLAPAPAP 160
AP A A PP PA + G Q P P P PA PP L P P
Sbjct: 77 APAEGAPGAAPEPP--PAGRARPG--GGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEG 132
Query: 161 APAPVAAPVAAPVAVAVLAPAPAPA-PAPAPAPAPVAAPA-PAPAPAPAPAPAPAPAPDA 218
+ A APV A AVA P PAPA PA PA +AA A P P P P P P P P A
Sbjct: 133 S-AGSCAPVPAAAAVAA-GPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPA 190
Query: 219 APQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANG-AAIKKLSGPLISDFFA 277
P GA Q G L + H+ AA + NG AA+ L P
Sbjct: 191 GP------GAAQTLNGSAALLNSHHA------AAPAVSLVNNGPAALLPLPKPAAPGTVI 238
Query: 278 KRKRSAPEKSSGDVPAP-CPSPSAAPGVGSVEQTP 311
++ P + PAP PSP AAP + P
Sbjct: 239 ---QTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAP 270
Score = 70.9 bits (172), Expect = 1e-12
Identities = 63/201 (31%), Positives = 84/201 (41%), Gaps = 35/201 (17%)
Query: 122 AAESLDGLEEAPEQLPSVPVPAPAS------TPPPVPVLAPAPAPAPAPVAAPVAAPVAV 175
AA ++ + P L +P+P PA+ TPP V AP AP+P AAP A
Sbjct: 211 AAPAVSLVNNGPAAL--LPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPA---- 264
Query: 176 AVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQ 235
APA AP P P PAPA +A P PA P APA P +A+ G + G
Sbjct: 265 ---APAAAP-PPPPPAPATLARPPGHPAGPPTAAPA------VPPPAAAQNGGSAGAAPA 314
Query: 236 EPLADQLHSGISGRPAAGTAAA-------SANGAAIKKLSGPLISDFFAKRKRSAPEK-- 286
A +G+SG+P G AAA + + + + + P A S
Sbjct: 315 PAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMV 374
Query: 287 ----SSGDVPAPCPSPSAAPG 303
G +P+P P APG
Sbjct: 375 IGPTMQGALPSPAAVPPPAPG 395
Score = 32.0 bits (71), Expect = 0.74
Identities = 30/116 (25%), Positives = 43/116 (37%), Gaps = 2/116 (1%)
Query: 106 PRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPV 165
P P A A A +P ++ A ++ AP ++ PAST + + P+P
Sbjct: 329 PGPGAAAAAPAPGVK-AESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPA 387
Query: 166 AAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAP-APAPDAAP 220
A P AP L A A + + P A + A AP P P P
Sbjct: 388 AVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNP 443
>gi|68563515 keratinocyte proline-rich protein [Homo sapiens]
Length = 579
Score = 71.2 bits (173), Expect = 1e-12
Identities = 43/126 (34%), Positives = 51/126 (40%), Gaps = 14/126 (11%)
Query: 106 PRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPV 165
PRP+ + PP LD E+P Q P P P P P L P P P P +
Sbjct: 376 PRPLP---SFCPP-----RRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQL 427
Query: 166 AAPVAAPVAVAVLAPAPAPAPAPAPA------PAPVAAPAPAPAPAPAPAPAPAPAPDAA 219
+ P P + L P P P P P P P P P P P P P P P PAP +
Sbjct: 428 SEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPS 487
Query: 220 PQESAE 225
P+ E
Sbjct: 488 PEPCRE 493
Score = 64.3 bits (155), Expect = 1e-10
Identities = 39/109 (35%), Positives = 45/109 (41%), Gaps = 9/109 (8%)
Query: 114 AVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPV 173
A P L P E LE P LP + P P P+P L P P P P P P
Sbjct: 403 APRPRLRP--EPCISLEPRPRPLPR-QLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPE 459
Query: 174 AVAVLAPAPAPAPAPAPAPAPVAAPAPAPAP------APAPAPAPAPAP 216
L P P P P P P P+ AP P+P P +P+P P P P
Sbjct: 460 PRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVP 508
Score = 53.1 bits (126), Expect = 3e-07
Identities = 47/160 (29%), Positives = 60/160 (37%), Gaps = 18/160 (11%)
Query: 104 LAPRPVAVAVAVSPP-LEPAAESLDGLEEAPEQLP-------SVPVPAPASTPPPVPVLA 155
L PRP + +S P L P E L L P +P +P P P P P
Sbjct: 416 LEPRPRPLPRQLSEPCLYP--EPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPC 473
Query: 156 PAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 215
P P P P P P P +P+P P P P P + +P AP P+
Sbjct: 474 PRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPS 533
Query: 216 PDAAPQESAEQGANQG-----QRGQEPLADQ--LHSGISG 248
QES G G +RGQ+ DQ +G+ G
Sbjct: 534 SYNQGQESG-AGCGPGDVFPERRGQDGHGDQGNAFAGVKG 572
Score = 41.2 bits (95), Expect = 0.001
Identities = 27/84 (32%), Positives = 30/84 (35%), Gaps = 8/84 (9%)
Query: 145 ASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAP 204
AS P P + P P P+ P P + P PAP P P P P P P P
Sbjct: 365 ASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLP 424
Query: 205 A--------PAPAPAPAPAPDAAP 220
P P PA P P P
Sbjct: 425 RQLSEPCLYPEPLPALRPTPRPVP 448
>gi|153791535 general control of amino acid synthesis 5-like 2 [Homo
sapiens]
Length = 837
Score = 70.1 bits (170), Expect = 2e-12
Identities = 41/97 (42%), Positives = 51/97 (52%), Gaps = 4/97 (4%)
Query: 160 PAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAA 219
P+ AP AP A P + APAP P PAP+PA AP+ P PAPAPAPA APA +
Sbjct: 4 PSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGTGGP 63
Query: 220 PQES--AEQGANQGQRG--QEPLADQLHSGISGRPAA 252
S A G + + G Q+ A Q + + G P A
Sbjct: 64 GVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRA 100
Score = 68.9 bits (167), Expect = 5e-12
Identities = 45/107 (42%), Positives = 50/107 (46%), Gaps = 15/107 (14%)
Query: 156 PAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 215
P+ AP PAP A P P +PAPAP P PAP +PA AP P P PAPAPAPA
Sbjct: 4 PSQAPTPAPAAQP----------RPLQSPAPAPTPTPAP--SPASAPIPTPTPAPAPAPA 51
Query: 216 PDAAPQESAEQGA-NQGQRGQEPLADQLHSGISGRPAAGTAAASANG 261
AAP S G G G D G+S + A A G
Sbjct: 52 --AAPAGSTGTGGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRG 96
Score = 64.7 bits (156), Expect = 1e-10
Identities = 38/91 (41%), Positives = 47/91 (51%), Gaps = 9/91 (9%)
Query: 140 PVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPA 199
P PAPA+ P P+ +PAPAP P P +P +AP+ P P PAPAPAPA AP A
Sbjct: 8 PTPAPAAQPRPLQ--SPAPAPTPTPAPSPASAPI------PTPTPAPAPAPAAAP-AGST 58
Query: 200 PAPAPAPAPAPAPAPAPDAAPQESAEQGANQ 230
P A + A P S +Q A+Q
Sbjct: 59 GTGGPGVGSGGAGSGGDPARPGLSQQQRASQ 89
Score = 30.4 bits (67), Expect = 2.1
Identities = 17/49 (34%), Positives = 20/49 (40%), Gaps = 7/49 (14%)
Query: 116 SPPLEPAAESLDGLEEAPEQLP-------SVPVPAPASTPPPVPVLAPA 157
+P PAA+ AP P S P+P P P P P APA
Sbjct: 7 APTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPA 55
Score = 28.5 bits (62), Expect = 8.2
Identities = 14/41 (34%), Positives = 18/41 (43%)
Query: 270 PLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQT 310
PL S A AP +S +P P P+P+ AP T
Sbjct: 18 PLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGST 58
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 69.3 bits (168), Expect = 4e-12
Identities = 51/196 (26%), Positives = 76/196 (38%), Gaps = 14/196 (7%)
Query: 108 PVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAP-APAPAPAPVA 166
P + PP P + +++ Q P P P + P PV A AP PA A
Sbjct: 841 PKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKA 900
Query: 167 APVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQ 226
P P ++ V +P P P + P P+P PAP P P P +P PD + +
Sbjct: 901 KPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKT 960
Query: 227 GANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGP----LISDFFAKRKRS 282
G++P P ++ S++GA + P L+S F +
Sbjct: 961 SKTSSPGGKKP---------PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESG 1011
Query: 283 APEKSSGDVPAPCPSP 298
+P K + PA P P
Sbjct: 1012 SPSKETLPPPAAPPKP 1027
Score = 61.6 bits (148), Expect = 9e-10
Identities = 40/129 (31%), Positives = 51/129 (39%), Gaps = 13/129 (10%)
Query: 106 PRPVAVAVAVSPPLEPAAESLDGLEEAP-----EQLPSVPVPAPASTPPPVPVLAPAPAP 160
P P + + P P A SL P Q+ + AP + PPP P+ AP P
Sbjct: 719 PTPGSAMAQLKPA--PCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQ 776
Query: 161 APAPVAAPVAAPVAVAVLAPA------PAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAP 214
AP + AP + +AP P P P PA A PA P+P P P P
Sbjct: 777 APPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVP 836
Query: 215 APDAAPQES 223
P Q+S
Sbjct: 837 PPTLPKQQS 845
Score = 54.3 bits (129), Expect = 1e-07
Identities = 53/192 (27%), Positives = 66/192 (34%), Gaps = 11/192 (5%)
Query: 111 VAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVA 170
VA PP P L +AP + P V +PAP ST PV+ A P P P P
Sbjct: 758 VAPPTPPPPPPIPAPLP--PQAPPK-PLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAK 814
Query: 171 APVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQ 230
A P+P P P P P + P P+P +P P Q ++
Sbjct: 815 KQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPL-SPVPSVVKQIAS------ 867
Query: 231 GQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGD 290
Q P + S A A S K P + P +SS
Sbjct: 868 -QFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLV 926
Query: 291 VPAPCPSPSAAP 302
P P PSP AP
Sbjct: 927 FPPPPPSPVPAP 938
Score = 50.8 bits (120), Expect = 2e-06
Identities = 40/136 (29%), Positives = 49/136 (36%), Gaps = 28/136 (20%)
Query: 117 PPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAV- 175
PPL P + + + P P P P PPP P P P P+ + +A AAP+ V
Sbjct: 607 PPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVK 666
Query: 176 ---------------AVLAPAPAPA-------PAPAPAPAPVAAPAPAPAPAPAPAPA-- 211
A+ P P P P V P P P P P P A
Sbjct: 667 YSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMA 726
Query: 212 ---PAPAPDAAPQESA 224
PAP + PQ SA
Sbjct: 727 QLKPAPCAPSLPQFSA 742
Score = 46.2 bits (108), Expect = 4e-05
Identities = 34/112 (30%), Positives = 41/112 (36%), Gaps = 9/112 (8%)
Query: 117 PPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVP-----VLAPAPAPAPAPVAAPVAA 171
PP P +S + V P P PPP P L PAP P +
Sbjct: 686 PPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPP 745
Query: 172 PVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAP---APAPAPAPDAAP 220
P+ + + AP P P P+ AP P AP P P PAP AP
Sbjct: 746 PLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAP-PKPLVTIPAPTSTKTVAP 796
Score = 43.1 bits (100), Expect = 3e-04
Identities = 37/127 (29%), Positives = 47/127 (37%), Gaps = 25/127 (19%)
Query: 101 RLLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPP---------V 151
++L+ P V PP ++ L+ AP PS+P S PPP +
Sbjct: 700 QILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAP-CAPSLP---QFSAPPPPLKIHQVQHI 755
Query: 152 PVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPA---PAPAPAPVAAPAPAPAPAPAP 208
+AP P P P+ AP L P P P PAP AP A P P
Sbjct: 756 TQVAPPTPPPPPPIPAP---------LPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTP 806
Query: 209 APAPAPA 215
P PA
Sbjct: 807 TPPVPPA 813
Score = 38.9 bits (89), Expect = 0.006
Identities = 37/139 (26%), Positives = 52/139 (37%), Gaps = 16/139 (11%)
Query: 175 VAVLAPAPA-PAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQR 233
V L+P P P A P+P P P P P P P P P P P Q + G+
Sbjct: 606 VPPLSPQPKIVTPYTASQPSP-PLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMF 664
Query: 234 GQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDV-P 292
+ +L + A+ +GA K + P++ K + P +G V P
Sbjct: 665 VKYSTITRLQN-----------ASQHSGALFKPPTPPVMQSQSVKPQILVP--PNGVVPP 711
Query: 293 APCPSPSAAPGVGSVEQTP 311
P P P PG + P
Sbjct: 712 PPPPPPPPTPGSAMAQLKP 730
Score = 36.2 bits (82), Expect = 0.039
Identities = 21/65 (32%), Positives = 28/65 (43%), Gaps = 3/65 (4%)
Query: 150 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 209
P L P +P P V A+ + + P P P P P P P P P P P+ + A
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPP---PPPLPSQSAPSA 657
Query: 210 PAPAP 214
+ AP
Sbjct: 658 GSAAP 662
Score = 35.0 bits (79), Expect = 0.087
Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 7/78 (8%)
Query: 130 EEAPEQLPSVPVPAPASTPPPVP---VLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAP 186
E + ++ S+ P + PP P ++ P A P+P P P P P P P
Sbjct: 589 ESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPP----PPPPPPPP 644
Query: 187 APAPAPAPVAAPAPAPAP 204
P P P+ A A + AP
Sbjct: 645 PPPPLPSQSAPSAGSAAP 662
Score = 33.9 bits (76), Expect = 0.19
Identities = 27/104 (25%), Positives = 39/104 (37%), Gaps = 6/104 (5%)
Query: 102 LLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVP-----VLAP 156
L+ P P + A PP P A +P + S PPP P + +
Sbjct: 925 LVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSS 984
Query: 157 APAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAP 200
+ A P P V + V+ PA + +P+ P P A P P
Sbjct: 985 SGAEHPEPKRPSVDSLVS-KFTPPAESGSPSKETLPPPAAPPKP 1027
Score = 30.0 bits (66), Expect = 2.8
Identities = 27/107 (25%), Positives = 39/107 (36%), Gaps = 6/107 (5%)
Query: 116 SPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPP-----PVPVLAPAPAPAPAPVAAPVA 170
+P + +S G E + PSV TPP P P PA P P ++
Sbjct: 974 TPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLS 1033
Query: 171 APVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPD 217
VL A AP + + P+P P+ + P P P+
Sbjct: 1034 GVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSP-PSDSDFPPPPPE 1079
>gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog A
isoform 2 [Homo sapiens]
Length = 548
Score = 68.2 bits (165), Expect = 9e-12
Identities = 65/213 (30%), Positives = 81/213 (38%), Gaps = 39/213 (18%)
Query: 129 LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVA---------------------- 166
++++P P+ P P P P A P PAP P
Sbjct: 310 MKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQ 369
Query: 167 ---APVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA---PAPAPDAAP 220
A AP VL APAPAPAPA A APAP P AP P A PAP P A
Sbjct: 370 ISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAG 429
Query: 221 QESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSG---PLISDFFA 277
+ + + Q Q E L L G S PA T AS + + ++L P+
Sbjct: 430 EGTLSEALLQLQFDDEDLGALL--GNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTE 487
Query: 278 KRKRSAPEKSSGDV------PAPCPSPSAAPGV 304
PE + V P P P+P APG+
Sbjct: 488 PMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGL 520
Score = 29.3 bits (64), Expect = 4.8
Identities = 19/71 (26%), Positives = 31/71 (43%), Gaps = 2/71 (2%)
Query: 82 VDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPV 141
++ D P + Q+ + L AP P V + +P PA + L +AP +P +
Sbjct: 355 INYDEFPTMVFPSGQISQASAL-APAPPQV-LPQAPAPAPAPAMVSALAQAPAPVPVLAP 412
Query: 142 PAPASTPPPVP 152
P + PP P
Sbjct: 413 GPPQAVAPPAP 423
>gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog A
isoform 1 [Homo sapiens]
Length = 551
Score = 68.2 bits (165), Expect = 9e-12
Identities = 65/213 (30%), Positives = 81/213 (38%), Gaps = 39/213 (18%)
Query: 129 LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVA---------------------- 166
++++P P+ P P P P A P PAP P
Sbjct: 313 MKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQ 372
Query: 167 ---APVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA---PAPAPDAAP 220
A AP VL APAPAPAPA A APAP P AP P A PAP P A
Sbjct: 373 ISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAG 432
Query: 221 QESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSG---PLISDFFA 277
+ + + Q Q E L L G S PA T AS + + ++L P+
Sbjct: 433 EGTLSEALLQLQFDDEDLGALL--GNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTE 490
Query: 278 KRKRSAPEKSSGDV------PAPCPSPSAAPGV 304
PE + V P P P+P APG+
Sbjct: 491 PMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGL 523
Score = 29.3 bits (64), Expect = 4.8
Identities = 19/71 (26%), Positives = 31/71 (43%), Gaps = 2/71 (2%)
Query: 82 VDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPV 141
++ D P + Q+ + L AP P V + +P PA + L +AP +P +
Sbjct: 358 INYDEFPTMVFPSGQISQASAL-APAPPQV-LPQAPAPAPAPAMVSALAQAPAPVPVLAP 415
Query: 142 PAPASTPPPVP 152
P + PP P
Sbjct: 416 GPPQAVAPPAP 426
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 68.2 bits (165), Expect = 9e-12
Identities = 67/235 (28%), Positives = 81/235 (34%), Gaps = 38/235 (16%)
Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLP-------SVPVPAPASTPPPVPVLAPA 157
AP P A A SP PA S G P P + P P A TPP V +P
Sbjct: 962 APTPPA-ATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK 1020
Query: 158 PAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAP-----------AP 206
+PA P + P A +P +PA P P AP A P+P AP
Sbjct: 1021 GSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP 1080
Query: 207 APAPAPAPAPDAAPQESAEQGANQGQRGQEP-----LADQLHSGISGRPAA-------GT 254
P A P+P P + +GA P LA H G PAA G
Sbjct: 1081 TPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL 1140
Query: 255 AAASANGAAIKKLSGPLI--SDFFAKRKRSAPEKSSGDVPAP-----CPSPSAAP 302
A GA + P + AP + P+P PSP AP
Sbjct: 1141 ATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195
Score = 64.7 bits (156), Expect = 1e-10
Identities = 66/209 (31%), Positives = 81/209 (38%), Gaps = 42/209 (20%)
Query: 106 PRPVAVAVAVSP---PLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPA- 161
P P + + SP P PAA +P+ P+ P P A TPP +P PA
Sbjct: 925 PAPKGIPASPSPKGAPTPPAATP-----PSPKGGPATPSPKWAPTPPAATPPSPKGGPAT 979
Query: 162 PAPVAAPVAAPVAVAVLAPAPAPA-PAPAPAPAP--VAAPAPAPAPAPAPAPAPAPAPDA 218
P+P AP P A +P PA P+P AP P V P+P +PA P P A P A
Sbjct: 980 PSPKGAPT--PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037
Query: 219 APQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAK 278
A S + P A L G PAA T + G A L G
Sbjct: 1038 ATPPSPK---------GSPAATPLPKGAPTTPAA-TLPSPKGGPATPSLKG--------- 1078
Query: 279 RKRSAPEKSSGDVPAP-----CPSPSAAP 302
AP + P+P PSP AP
Sbjct: 1079 ----APTPPAATPPSPKGGPATPSPKGAP 1103
Score = 60.8 bits (146), Expect = 1e-09
Identities = 71/261 (27%), Positives = 91/261 (34%), Gaps = 65/261 (24%)
Query: 108 PVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAP----- 162
P AV P EP A +P++ P+ P P A T P V +P PA
Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRR 1524
Query: 163 ---APVA-----------APVAAPVAVAVLAPAPAPAPA-PAPAPAPV--------AAPA 199
AP A AP A + A+ P+P PA P P AP + PA
Sbjct: 1525 DPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA 1584
Query: 200 PAP-----APAP----------APAPAPAPAPDAAPQESAEQG-ANQGQRGQEPLADQLH 243
P AP+P +P+P AP P A S E+G A +G
Sbjct: 1585 VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTP 1644
Query: 244 SGISGRPAAGTAAASANGAAIKKLS-------GP--LISDFFAKRKRSAP---------- 284
S + P + + GA + + S GP L A S P
Sbjct: 1645 SSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGP 1704
Query: 285 --EKSSGDVPAPCPSPSAAPG 303
+KSS P CP PSA G
Sbjct: 1705 QTKKSSATSPPICPDPSAKNG 1725
Score = 58.9 bits (141), Expect = 6e-09
Identities = 71/242 (29%), Positives = 91/242 (37%), Gaps = 37/242 (15%)
Query: 105 APRPVAVAV-----AVSPPLEPAAESLDGLEEAPEQLPSVPVP--APA------------ 145
AP P AV PP E S+ L P++ P+ P P APA
Sbjct: 864 APTPSAVTPLSPKGVTLPPKETPTPSVVNLP-FPKEGPATPAPKQAPALSMTSSSPKKAR 922
Query: 146 STPPPVPVLAPAPAP--APAPVAAPVAAPV-AVAVLAPAPAPAPAPAPAPAPVAAPA-PA 201
+TP P + A +P+P AP P AA +P A +P AP P A P+P PA P+
Sbjct: 923 ATPAPKGIPA-SPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPS 981
Query: 202 PAPAPAPAPAPAPAPDAAPQESAEQGA------NQGQRGQEPLADQLHSGISGRPAAGTA 255
P AP P A P+P P + +GA P A G S PAA
Sbjct: 982 PKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPP 1041
Query: 256 AASANGAAIKKLSG----PLISDFFAKRKRSAPEKSSGDVP--APCPSPSAAPGVGSVEQ 309
+ + AA G P + K + P P A PSP P S +
Sbjct: 1042 SPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG 1101
Query: 310 TP 311
P
Sbjct: 1102 AP 1103
Score = 52.4 bits (124), Expect = 5e-07
Identities = 65/232 (28%), Positives = 83/232 (35%), Gaps = 42/232 (18%)
Query: 105 APRPVAVAVAVSPPLEP---AAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPA 161
+P+ A +PP A S G P P P PA+ PP AP P A
Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPK---GAPTPPAA 1269
Query: 162 PAP-----VAAP--VAAPVAVAVLAPAPAPAPAPAP---APAPVAAPAPAP-----APAP 206
P +A P AP V P+P PA +P AP P AA P+P P P
Sbjct: 1270 TPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPP 1329
Query: 207 APAPAP----APAPDAAPQESAEQGANQG--------QRGQEPLADQLHSG----ISGRP 250
AP P P+P P A +++G + P A H G P
Sbjct: 1330 KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSP 1389
Query: 251 AAGTAAASANG----AAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSP 298
G A S G A+ LS P + + A S GD+ P +P
Sbjct: 1390 KRGPAIPSPKGDPTSPAVIPLS-PKKAPATPVTREGAATPSKGDLTPPAVTP 1440
Score = 51.6 bits (122), Expect = 9e-07
Identities = 67/273 (24%), Positives = 95/273 (34%), Gaps = 63/273 (23%)
Query: 105 APRPVAVAVA---------------------VSPPLEPA--------AESLDGLEEAP-- 133
+P P+ V+V+ +S P+ P + S G +++P
Sbjct: 793 SPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPAT 852
Query: 134 EQLPSVPVPAPASTPPPVPVLAP--------------------------APAPAPAPVAA 167
P+ P P A TP V L+P PAP AP +
Sbjct: 853 THSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALS 912
Query: 168 PVAAPVAVAVLAPAP---APAPAPAPAPAPVAAPAPAPAPAPA-PAPAPAPAPDAAPQES 223
++ A PAP +P+P AP P AA P+P PA P+P AP P AA S
Sbjct: 913 MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPS 972
Query: 224 AEQG-ANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRS 282
+ G A +G G PA + + A+ S P S +
Sbjct: 973 PKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS-PKGSPAATPFPKG 1031
Query: 283 APEKSSGDVPAPCPSPSAAPGVGSVEQTPRKRL 315
A + P+P SP+A P TP L
Sbjct: 1032 ASTPPAATPPSPKGSPAATPLPKGAPTTPAATL 1064
Score = 50.1 bits (118), Expect = 3e-06
Identities = 66/248 (26%), Positives = 82/248 (33%), Gaps = 53/248 (21%)
Query: 112 AVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPP---PVPVLAPAPAP-------- 160
A SP PA SL G P P P PA+ P P+P A P+P
Sbjct: 1062 ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121
Query: 161 ---APAPVAA-------------PVAAPVAVAVLAPAPA---PAPAPAPAPAPVAAPAPA 201
AP AA P AP A P+P P P AP AA P+
Sbjct: 1122 HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1181
Query: 202 P-----APAPAPAP----APAPAPDAAPQESAEQGANQGQRGQEP-----LADQLHSGIS 247
P P+P AP A P+P + +GA P LA G
Sbjct: 1182 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1241
Query: 248 GRPAA-------GTAAASANGAAIKKLSGP--LISDFFAKRKRSAPEKSSGDVPAPCPSP 298
PAA G A GA + P L + AP + P+P P
Sbjct: 1242 TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP 1301
Query: 299 SAAPGVGS 306
+ +P G+
Sbjct: 1302 ATSPPKGA 1309
Score = 48.9 bits (115), Expect = 6e-06
Identities = 37/115 (32%), Positives = 46/115 (40%), Gaps = 2/115 (1%)
Query: 116 SPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAV 175
SP PA S G +P +P P APA+ P+ P PV+ A
Sbjct: 1388 SPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAP 1447
Query: 176 AVLAPAPAPA-PAPAPAPAPVAAPAPAPAPAPAPAP-APAPAPDAAPQESAEQGA 228
A AP PA P+ P A P+P PAP A + +P AP A GA
Sbjct: 1448 ATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA 1502
Score = 42.7 bits (99), Expect = 4e-04
Identities = 62/236 (26%), Positives = 83/236 (35%), Gaps = 39/236 (16%)
Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQL--PSVPVPAPASTPPPVPVLAPAP--AP 160
AP + A SPP + + G E L P+V P+P P P V P+P P
Sbjct: 1570 APATPSSKEASSPPAVTPS-TYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP 1628
Query: 161 A-PAPVAAPVAAPVAVAVLAPAP-APA-----------------PA---PAPAPAPVAAP 198
A PAP P + PV + L +P +PA PA P + AP
Sbjct: 1629 ATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP 1688
Query: 199 APAPAP--------APAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRP 250
AP P P + A +P P SA+ G+ P S +
Sbjct: 1689 APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKT 1748
Query: 251 AAGTAAASANGAAI----KKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAP 302
A G A+ + + K S PL + F K S P+P S AP
Sbjct: 1749 AKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAP 1804
Score = 40.4 bits (93), Expect = 0.002
Identities = 45/184 (24%), Positives = 72/184 (39%), Gaps = 16/184 (8%)
Query: 115 VSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPV---LAPAPAPAPAPVAAPVAA 171
++PP A+ L A E++ P A S P PV LAP+P P P + +
Sbjct: 1762 LAPPESKASTPLTAA--AFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPS 1819
Query: 172 PVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA-----PAPAPAPDAAPQESAEQ 226
+ + +P+ APA P+ P P P + P P A P SA+Q
Sbjct: 1820 SPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQ 1879
Query: 227 GANQGQRGQ--EPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAP 284
+ +G E +D+ + + + A AA ++ +S K K+S
Sbjct: 1880 PVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVS----KAKQSRS 1935
Query: 285 EKSS 288
EK +
Sbjct: 1936 EKKA 1939
Score = 37.7 bits (86), Expect = 0.013
Identities = 52/241 (21%), Positives = 78/241 (32%), Gaps = 37/241 (15%)
Query: 109 VAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAP-APAPAPAPVAA 167
V++A P E +L + A E P P P P VLAP P P+P
Sbjct: 681 VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLP 740
Query: 168 PVAAPVA---------VAVLAPAPAPAPAPAPA-PAPVAAPAPAPAPAPAPAPAPAPAPD 217
P P + LAP A +P P + +A A + A +P+P
Sbjct: 741 PAGTPPGTKKVDGISHTSALAPV-ASSPKECPTEDSGASATASSKGTLTYLADSPSPLGV 799
Query: 218 AAPQESAEQGANQGQRGQEPLADQLHSGISGRPAA--------------------GTAAA 257
+ ++ +G G + L S +S A+
Sbjct: 800 SVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPP 859
Query: 258 SANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAP-----CPSPSAAPGVGSVEQTPR 312
S GA PL + P S ++P P P+P AP + +P+
Sbjct: 860 SPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPK 919
Query: 313 K 313
K
Sbjct: 920 K 920
Score = 35.0 bits (79), Expect = 0.087
Identities = 30/124 (24%), Positives = 48/124 (38%), Gaps = 10/124 (8%)
Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAP 164
+P P +A +P P +S G P P P PP+ +PA +P
Sbjct: 65 SPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPI---SPAALALASP 121
Query: 165 VAAPV-------AAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPD 217
+ AP +AP+A+ LAP + P + P+ A A + + AP
Sbjct: 122 MIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAP 181
Query: 218 AAPQ 221
+ P+
Sbjct: 182 SEPK 185
Score = 33.5 bits (75), Expect = 0.25
Identities = 44/172 (25%), Positives = 63/172 (36%), Gaps = 18/172 (10%)
Query: 131 EAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAP 190
EA E +P+ P P A P+++ ++ A+ P P +PAP
Sbjct: 4 EATETVPATEQELPQ----------PQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAP 53
Query: 191 APAPVAAPAPAPAPAPAPAP-APAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGR 249
P++A A +P P+P+ A P PQ S+ G P A + G
Sbjct: 54 QQCPLSA-ANQASPFPSPSTIASTPLEVPFPQSSSGTAL---PLGTAPEAPTFLPNLIGP 109
Query: 250 PAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAP---EKSSGDVPAPCPSP 298
P + A A A+ L G S AP +KSS P SP
Sbjct: 110 PISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSP 161
Score = 31.6 bits (70), Expect = 0.96
Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 10/71 (14%)
Query: 102 LLLAPRPVAVA-----VAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAP 156
LL +P VAVA + +S P+ P+ E L + P ++ VP P TP P +++
Sbjct: 157 LLTSPPSVAVAESGSVITLSAPIAPS-EPKTNLNKVPSEV----VPNPKGTPSPPCIVST 211
Query: 157 APAPAPAPVAA 167
P P+A+
Sbjct: 212 VPYHCVTPMAS 222
Score = 31.2 bits (69), Expect = 1.3
Identities = 27/105 (25%), Positives = 41/105 (39%), Gaps = 9/105 (8%)
Query: 114 AVSPPLEPAAESLDGLE---EAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVA 170
A SPP+ P + +G + P +PV +S + +P AP + +
Sbjct: 1711 ATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAS 1770
Query: 171 APVAVAV---LAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAP 212
P+ A + P P A A PV+ P AP+P P P
Sbjct: 1771 TPLTAAAFEKVLPKPESASVSAAPSPPVSLPL---APSPVPTLPP 1812
Score = 29.6 bits (65), Expect = 3.7
Identities = 31/112 (27%), Positives = 41/112 (36%), Gaps = 5/112 (4%)
Query: 108 PVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAP-APAPAPAPVA 166
P++ A SP P+ + LE P S P T P P P P +P A
Sbjct: 57 PLSAANQASPFPSPSTIASTPLE-VPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAA 115
Query: 167 APVAAPVAVAVLAPAP---APAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 215
+A+P+ L P AP A AP V + P P+ A A
Sbjct: 116 LALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVA 167
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 67.0 bits (162), Expect = 2e-11
Identities = 47/138 (34%), Positives = 62/138 (44%), Gaps = 14/138 (10%)
Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAP-----ASTPPPVPVLAPAPA 159
+PRP A + SP + AA S + + P+ P P P AS P V PA
Sbjct: 360 SPRPQASSY--SPAV--AASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPAST 415
Query: 160 PAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAA 219
+P+P A P P+PAPA P+PAPA +P P P+PAPA P+PAP+
Sbjct: 416 YSPSPGANYSPTPYT-----PSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYN 470
Query: 220 PQESAEQGANQGQRGQEP 237
P S + P
Sbjct: 471 PAPSVAYSGGPAEPASRP 488
Score = 58.5 bits (140), Expect = 7e-09
Identities = 39/97 (40%), Positives = 45/97 (46%), Gaps = 10/97 (10%)
Query: 137 PSVPVPAPASTPPPVP-------VLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPA 189
PSV P PAST P P P+PAPA P AP P V P+PAPA P+
Sbjct: 405 PSVYQPVPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPS 464
Query: 190 PAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQ 226
PAP AP+ A + PA PA P +S Q
Sbjct: 465 PAPNYNPAPSVAYSGGPA---EPASRPPWVTDDSFSQ 498
Score = 52.0 bits (123), Expect = 7e-07
Identities = 56/205 (27%), Positives = 75/205 (36%), Gaps = 16/205 (7%)
Query: 117 PPLEPAAESLDGLEEAPEQLPSVPVPA-PASTPPPVPVLAPAPAPAPAPVAAPVAAPVAV 175
P E S +E AP P PAS PP +P+ A P AA A +
Sbjct: 290 PDEEALRRSSTPIEHAPVCTSQATTPLLPASAQPPAAA-SPSAASPPLATAAAHTAIASA 348
Query: 176 AVLAPAPAPAPAPAP-----APAPVAAPAPAPAPAPAPAP-APAPAPDAAPQESAEQGAN 229
+ APA +PA +P P +PA A+ APA + + P APAP P S
Sbjct: 349 STTAPASSPADSPRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVY 408
Query: 230 QGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSG 289
Q P+ +S G + T + A P + +P +
Sbjct: 409 Q------PVPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYT 462
Query: 290 DVPAP--CPSPSAAPGVGSVEQTPR 312
PAP P+PS A G E R
Sbjct: 463 PSPAPNYNPAPSVAYSGGPAEPASR 487
>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
Length = 808
Score = 66.6 bits (161), Expect = 3e-11
Identities = 70/222 (31%), Positives = 86/222 (38%), Gaps = 41/222 (18%)
Query: 111 VAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVA 170
V VA PP+ A AP L + PA P APAPAPAPAP A
Sbjct: 34 VVVAPGPPVTTATS-------APVTLVAPGEARPAWVPGSAETSAPAPAPAPAPAPAVTG 86
Query: 171 APVAVAVLAPAP-APAP-----APAPAPAPV---------AAPAPAPAPAPA-PAPAPAP 214
+ V V L +P AP P +P PA V AA A +P A P+PAP P
Sbjct: 87 STVVVLTLEASPEAPKPQLPSGPESPEPAAVAGVETSRALAAGADSPKTEEARPSPAPGP 146
Query: 215 -APDAAPQESAEQGANQGQRGQEPLADQ----LHSGISGRPAAGTAAASANGAAIKKLSG 269
P P + + A + PLA + + SG++ R A+G AA S
Sbjct: 147 GTPTGTPTRTPSRTAPGALTAKPPLAPKPGTTVASGVTARSASGQVTGGHGAAAATSASA 206
Query: 270 PLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTP 311
APE SG P PS + V V TP
Sbjct: 207 -----------GQAPEDPSG--PGTGPSGTCEAPVAVVTVTP 235
Score = 61.2 bits (147), Expect = 1e-09
Identities = 60/174 (34%), Positives = 74/174 (42%), Gaps = 14/174 (8%)
Query: 137 PSVPVPAP-ASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPV 195
P+ P P P S PV V+AP P PV +APV + +AP A PA P A
Sbjct: 18 PAAPSPPPRGSRAGPVVVVAPGP-----PVTTATSAPVTL--VAPGEA-RPAWVPGSAET 69
Query: 196 AAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGI--SGRPAAG 253
+APAPAPAPAPAPA + + S E Q G E +G+ S AAG
Sbjct: 70 SAPAPAPAPAPAPAVTGSTVVVLTLEASPEAPKPQLPSGPESPEPAAVAGVETSRALAAG 129
Query: 254 TAAASANGAAIKKLSGPLISDFFAKR--KRSAPEKSSGDVP-APCPSPSAAPGV 304
+ A GP R R+AP + P AP P + A GV
Sbjct: 130 ADSPKTEEARPSPAPGPGTPTGTPTRTPSRTAPGALTAKPPLAPKPGTTVASGV 183
Score = 38.9 bits (89), Expect = 0.006
Identities = 47/155 (30%), Positives = 55/155 (35%), Gaps = 23/155 (14%)
Query: 105 APRPVAVA-VAVSPPLEPAAESLDGLEEAPEQLPS------VPVPAPASTPPPVPVLAPA 157
+P P AVA V S L A+S E P P P P+ T P P
Sbjct: 111 SPEPAAVAGVETSRALAAGADSPKTEEARPSPAPGPGTPTGTPTRTPSRTAPGALTAKPP 170
Query: 158 PAPAPAP-VAAPVAAPVAV--------AVLAPAPAPAPAPAPAPAPVAAPA---PAPAPA 205
AP P VA+ V A A A A + + AP P P+ AP
Sbjct: 171 LAPKPGTTVASGVTARSASGQVTGGHGAAAATSASAGQAPEDPSGPGTGPSGTCEAPVAV 230
Query: 206 PAPAPAPAPA---PDAAPQESAEQGANQGQRGQEP 237
PAP PA D S G + G RGQ P
Sbjct: 231 VTVTPAPEPAENSQDLGSTSSLGPGIS-GPRGQAP 264
Score = 30.0 bits (66), Expect = 2.8
Identities = 42/154 (27%), Positives = 52/154 (33%), Gaps = 11/154 (7%)
Query: 167 APVAAPVAVAVLAPAPAPAPAPAPA-PAPVAAPAP---APAPAPAPAPAPAPAPDAAPQE 222
AP+ AP AP+P P + A P V AP P AP AP A A
Sbjct: 6 APLVAPPRRHGAPAAPSPPPRGSRAGPVVVVAPGPPVTTATSAPVTLVAPGEARPAWVPG 65
Query: 223 SAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRS 282
SAE A P S + T AS + SGP + A
Sbjct: 66 SAETSAPAPAPAPAPAPAVTGSTV----VVLTLEASPEAPKPQLPSGPESPEPAAVAGVE 121
Query: 283 APEKSSGDVPAPCPS---PSAAPGVGSVEQTPRK 313
+ +P PS APG G+ TP +
Sbjct: 122 TSRALAAGADSPKTEEARPSPAPGPGTPTGTPTR 155
>gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo
sapiens]
Length = 907
Score = 66.2 bits (160), Expect = 4e-11
Identities = 71/225 (31%), Positives = 84/225 (37%), Gaps = 36/225 (16%)
Query: 106 PRPVAVAVAVSPPLEPAAESLDGLEEAPE--------QLPSVPVPAP-ASTPPPVPVLAP 156
P PVA A+ +P A S E APE SVPV P AST PPVP AP
Sbjct: 464 PTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAP 523
Query: 157 APAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAP 216
+PAPA VAA AA A A A AP A P A AP P
Sbjct: 524 SPAPA---VAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKP 580
Query: 217 DAAPQ---------ESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAA--ASANGAAIK 265
DAAP S QGA+ AD L P+ T A A + + +
Sbjct: 581 DAAPSIDLFSTDAFSSPPQGASPVPE-SSLTADLLSVDAFAAPSPATTASPAKVDSSGVI 639
Query: 266 KLSGPLISDFFAKRKRSAPEKSS------------GDVPAPCPSP 298
L G ++ + ++ SS G AP PSP
Sbjct: 640 DLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSP 684
Score = 42.7 bits (99), Expect = 4e-04
Identities = 56/211 (26%), Positives = 70/211 (33%), Gaps = 62/211 (29%)
Query: 137 PSVPVPAPASTP-------PPVPVLAPAPAPAPAPVAAP----------VAAPVAVAVLA 179
P+ V +P STP PPV + A A A P + P ++ A A A
Sbjct: 307 PATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAA 366
Query: 180 PAPAPAPAPAPA------PAPVAAPAPAPAPAPAPAP-APAPAPDAAPQESAEQGANQGQ 232
PAP P A A +AA + P+ A P AP P P E A A+
Sbjct: 367 PAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASAS--- 423
Query: 233 RGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVP 292
A+ T +A A + L D FA AP S G
Sbjct: 424 ------------------ASTTTTVTAVTAEV-----DLFGDAFAASPGEAPAASEGAAA 460
Query: 293 APCPSPSA------------APGVGSVEQTP 311
P+P A AP GS E P
Sbjct: 461 PATPTPVAAALDACSGNDPFAPSEGSAEAAP 491
Score = 41.2 bits (95), Expect = 0.001
Identities = 55/232 (23%), Positives = 73/232 (31%), Gaps = 43/232 (18%)
Query: 110 AVAVAVSPPLEPAA-----------ESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAP 158
A A A P PA +SL L P + AP TPP
Sbjct: 361 AAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA 420
Query: 159 APAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDA 218
+ + + A V + A A +P APA + AA P P A A +
Sbjct: 421 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF 480
Query: 219 APQESAEQGANQ----GQRGQEPLADQLHSGISGRP----------------AAGTAAAS 258
AP E + + A + + E + S P AA T AA+
Sbjct: 481 APSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAAT 540
Query: 259 A------NGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGV 304
A +A + P D F S PE A P P AAP +
Sbjct: 541 AAATTTTTTSAATATTAPPALDIFGDLFESTPE------VAAAPKPDAAPSI 586
Score = 34.3 bits (77), Expect = 0.15
Identities = 28/100 (28%), Positives = 36/100 (36%), Gaps = 2/100 (2%)
Query: 104 LAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPA 163
+AP + V S PL+ A + PSV P PP P P
Sbjct: 799 VAPATWSAGVPPSAPLQGAVPPTSSVPPVAGA-PSVGQPGAGFGMPPAGTGMPMMPQQPV 857
Query: 164 PVAAPVAAPVAVAVLAPAPAPAPAPAPA-PAPVAAPAPAP 202
A P+ P A P +P+P PA +P PA P
Sbjct: 858 MFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDP 897
Score = 32.7 bits (73), Expect = 0.43
Identities = 56/226 (24%), Positives = 78/226 (34%), Gaps = 45/226 (19%)
Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAP---ASTPPPVPVLAP----- 156
AP P A SP ++ +D +A S P PA +S+ +LA
Sbjct: 621 APSPATTA---SPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSF 677
Query: 157 -APAPAPA-PVAAPVAAPVAVAVLAPAPAPAPAPAPAPA----------PVAAPAPAPAP 204
AP+P+P P + P A P+ + + + P+ P APA PAP
Sbjct: 678 MAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAP 737
Query: 205 APAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASAN---G 261
P+PA A A L L S + +GT +
Sbjct: 738 VSMVPPSPAMAASKALGSD--------------LDSSLASLVGNLGISGTTTKKGDLQWN 783
Query: 262 AAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSV 307
A KKL+G + + AP S VP P A P SV
Sbjct: 784 AGEKKLTGGA-----NWQPKVAPATWSAGVPPSAPLQGAVPPTSSV 824
Score = 32.3 bits (72), Expect = 0.57
Identities = 32/108 (29%), Positives = 39/108 (36%), Gaps = 11/108 (10%)
Query: 117 PPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPA------PAPVAAPVA 170
P + PA S AP Q +VP P S+ PPV P PA P+
Sbjct: 797 PKVAPATWSAGVPPSAPLQ-GAVP---PTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMM 852
Query: 171 APVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPA-PAPAPAPAPAPAPD 217
V P P A P +P+P PA +P PA P D
Sbjct: 853 PQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDPLAD 900
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,835,952
Number of Sequences: 37866
Number of extensions: 1457065
Number of successful extensions: 89213
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1618
Number of HSP's successfully gapped in prelim test: 1615
Number of HSP's that attempted gapping in prelim test: 15178
Number of HSP's gapped (non-prelim): 23900
length of query: 316
length of database: 18,247,518
effective HSP length: 102
effective length of query: 214
effective length of database: 14,385,186
effective search space: 3078429804
effective search space used: 3078429804
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.