Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 4557441

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
sapiens]
         (316 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ...   629   0.0  
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom...   610   e-175
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom...   610   e-175
gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]               95   7e-20
gi|45120115 hypothetical protein LOC56905 [Homo sapiens]               90   2e-18
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]                    89   4e-18
gi|62000702 diacylglycerol kinase kappa [Homo sapiens]                 88   9e-18
gi|4503519 eukaryotic translation initiation factor 3, subunit 5...    81   1e-15
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             80   2e-15
gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]          78   9e-15
gi|19111150 angiomotin isoform 2 [Homo sapiens]                        78   1e-14
gi|166064029 angiomotin isoform 1 [Homo sapiens]                       78   1e-14
gi|33356148 formin-like 1 [Homo sapiens]                               78   1e-14
gi|33286436 gametogenetin [Homo sapiens]                               77   2e-14
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     77   2e-14
gi|4757962 cyclin-dependent kinase inhibitor 1B [Homo sapiens]         75   8e-14
gi|24307909 ral guanine nucleotide dissociation stimulator isofo...    74   2e-13
gi|108796058 ral guanine nucleotide dissociation stimulator isof...    74   2e-13
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         72   6e-13
gi|153792074 proline rich 12 [Homo sapiens]                            72   6e-13
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    72   8e-13
gi|68563515 keratinocyte proline-rich protein [Homo sapiens]           71   1e-12
gi|153791535 general control of amino acid synthesis 5-like 2 [H...    70   2e-12
gi|47132519 Ras association and pleckstrin homology domains 1 is...    69   4e-12
gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog ...    68   9e-12
gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog ...    68   9e-12
gi|163965366 nascent polypeptide-associated complex alpha subuni...    68   9e-12
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]              67   2e-11
gi|167614488 TBC1 domain family, member 10B [Homo sapiens]             67   3e-11
gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo ...    66   4e-11

>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
           sapiens]
          Length = 316

 Score =  629 bits (1623), Expect = 0.0
 Identities = 316/316 (100%), Positives = 316/316 (100%)

Query: 1   MSDASLRSTSTMERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNR 60
           MSDASLRSTSTMERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNR
Sbjct: 1   MSDASLRSTSTMERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNR 60

Query: 61  WDYDFQQDMPLRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLE 120
           WDYDFQQDMPLRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLE
Sbjct: 61  WDYDFQQDMPLRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLE 120

Query: 121 PAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAP 180
           PAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAP
Sbjct: 121 PAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAP 180

Query: 181 APAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLAD 240
           APAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLAD
Sbjct: 181 APAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLAD 240

Query: 241 QLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSA 300
           QLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSA
Sbjct: 241 QLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSA 300

Query: 301 APGVGSVEQTPRKRLR 316
           APGVGSVEQTPRKRLR
Sbjct: 301 APGVGSVEQTPRKRLR 316


>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score =  610 bits (1573), Expect = e-175
 Identities = 305/305 (100%), Positives = 305/305 (100%)

Query: 12  MERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPL 71
           MERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPL
Sbjct: 1   MERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPL 60

Query: 72  RGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEE 131
           RGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEE
Sbjct: 61  RGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEE 120

Query: 132 APEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA 191
           APEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA
Sbjct: 121 APEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA 180

Query: 192 PAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPA 251
           PAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPA
Sbjct: 181 PAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPA 240

Query: 252 AGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTP 311
           AGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTP
Sbjct: 241 AGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTP 300

Query: 312 RKRLR 316
           RKRLR
Sbjct: 301 RKRLR 305


>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score =  610 bits (1573), Expect = e-175
 Identities = 305/305 (100%), Positives = 305/305 (100%)

Query: 12  MERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPL 71
           MERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPL
Sbjct: 1   MERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPL 60

Query: 72  RGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEE 131
           RGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEE
Sbjct: 61  RGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEE 120

Query: 132 APEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA 191
           APEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA
Sbjct: 121 APEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA 180

Query: 192 PAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPA 251
           PAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPA
Sbjct: 181 PAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPA 240

Query: 252 AGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTP 311
           AGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTP
Sbjct: 241 AGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTP 300

Query: 312 RKRLR 316
           RKRLR
Sbjct: 301 RKRLR 305


>gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]
          Length = 411

 Score = 95.1 bits (235), Expect = 7e-20
 Identities = 69/244 (28%), Positives = 95/244 (38%), Gaps = 14/244 (5%)

Query: 67  QDMPLRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAV--AVSPPLEPAAE 124
           Q  P R PG+       +  VPA      Q G   +L A  P   ++  A   P   A +
Sbjct: 27  QQQPQRVPGQRGRGARAAPLVPAASASAPQRGPSGILPAAEPTICSLHQAWGGPGCRAQK 86

Query: 125 SLDG-LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPA 183
            +   L   P  +P+ P+P PA  P P+P   P P P PA + +P+ AP+   +  P   
Sbjct: 87  GIPAALSPGPGPIPA-PIPGPAQIPGPLPGSIPGPIPGPAQIPSPIPAPIPGPISGPVQI 145

Query: 184 PAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLH 243
           P P   P P P++ PAP P P   P   P P P   P      G   G     P+   + 
Sbjct: 146 PGPFRGPIPGPISGPAPIPGPISGPFSGPNPGPIPGPNPGPIPGPISG-----PIPGPIS 200

Query: 244 SGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGD----VPAPCPSPS 299
             I G P  G  +   +G     + GP+            P   SG     +P P P P 
Sbjct: 201 VPIPG-PIPGPISGPISGPNPGPIPGPIPGPISGPNPGPIPGPISGPNPGLIPGPIPGPI 259

Query: 300 AAPG 303
           + PG
Sbjct: 260 SGPG 263



 Score = 75.1 bits (183), Expect = 8e-14
 Identities = 58/198 (29%), Positives = 72/198 (36%), Gaps = 32/198 (16%)

Query: 108 PVAVAVAVSPPLE-PAAESLDGLEEAPEQLP-SVPVPAPASTPPPVPVLAPAPAPAPAPV 165
           P  +   +S P   P    + G    P   P S P+P P S P P P+  P   P   P 
Sbjct: 160 PAPIPGPISGPFSGPNPGPIPGPNPGPIPGPISGPIPGPISVPIPGPIPGPISGPISGPN 219

Query: 166 AAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAE 225
             P+  P+      P P   P P P P P++ P P   P P P P   P P   P  S  
Sbjct: 220 PGPIPGPI------PGPISGPNPGPIPGPISGPNPGLIPGPIPGPISGPGPIIGPIPSPA 273

Query: 226 QGANQGQ-RGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAP 284
           Q    G+ +G  P+   L  G    P +    A   G      SGP              
Sbjct: 274 QIPGPGRLQGPGPI---LSPGRMRSPGSLPGLAPILGPG----SGP-------------- 312

Query: 285 EKSSGDVPAPCPSPSAAP 302
              SG VPAP P P + P
Sbjct: 313 --GSGSVPAPIPGPGSLP 328



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 42/151 (27%), Positives = 62/151 (41%), Gaps = 40/151 (26%)

Query: 106 PRPVAVAVAVSPPLE-PAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAP 164
           P P  ++V +  P+  P +  + G    P  +P  P+P P S P P P+  P   P P  
Sbjct: 194 PIPGPISVPIPGPIPGPISGPISGPNPGP--IPG-PIPGPISGPNPGPIPGPISGPNPGL 250

Query: 165 VAAPVAAPVAVA--VLAPAPAPAPAPAPA----PAPVAAPA------------------- 199
           +  P+  P++    ++ P P+PA  P P     P P+ +P                    
Sbjct: 251 IPGPIPGPISGPGPIIGPIPSPAQIPGPGRLQGPGPILSPGRMRSPGSLPGLAPILGPGS 310

Query: 200 -------PAPAPAPAPAPAPAP----APDAA 219
                  PAP P P   PAPAP    +PDA+
Sbjct: 311 GPGSGSVPAPIPGPGSLPAPAPLWPQSPDAS 341


>gi|45120115 hypothetical protein LOC56905 [Homo sapiens]
          Length = 1047

 Score = 90.1 bits (222), Expect = 2e-18
 Identities = 50/107 (46%), Positives = 58/107 (54%), Gaps = 20/107 (18%)

Query: 140 PVPAPASTPPPVPVLAPAPA-PAPAPVAAPVA-------------------APVAVAVLA 179
           P P PA+  P  P  APAP  PAP P + P+                    +P AVAV +
Sbjct: 659 PAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVAS 718

Query: 180 PAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQ 226
           PAPAPAP+PAPA A   A A  PAPAPAP   PAPA  +AP +S EQ
Sbjct: 719 PAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQ 765



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 52/149 (34%), Positives = 67/149 (44%), Gaps = 31/149 (20%)

Query: 74  PGRLQWTEVDSDSVPA--FYRETVQVGRCRLLLAPRPVAVAVAVSPPL------EPAAES 125
           PG L    V +D++P   F+     + R   +L P P+  AV  S P       +PA   
Sbjct: 626 PG-LPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTP 684

Query: 126 LDG------LEEAPEQLP--SVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAV 177
             G      L + P  +   S+ +P+P +     P  APAP+PAPA              
Sbjct: 685 TSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPA-------------- 730

Query: 178 LAPAPAPAPAPAPAPAPVAAPAPAPAPAP 206
            A APA A  PAPAPAPVA PAPA   AP
Sbjct: 731 RAQAPASARDPAPAPAPVAGPAPASTSAP 759



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 54/219 (24%), Positives = 86/219 (39%), Gaps = 20/219 (9%)

Query: 106 PRPVAVAVAVSP--PLEPAAESLDGLEEAPEQ--LPSVPV----PAPASTPPPVPVLAPA 157
           P+P A   A  P    +P +E +   +EA E+  LPS       P  +    P  V+  +
Sbjct: 408 PQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDS 467

Query: 158 PAPAPAPVAAPVAAPV-AVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAP 216
           P P   P   P A    ++     A  P+  P P    V + AP       PAP     P
Sbjct: 468 PVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEP 527

Query: 217 DAAPQE-----SAEQGANQGQRGQEPLADQLHSGISG-RPAAGTAAAS-ANGAAIKKLSG 269
           D+A  E     +  +G ++G RG  P  +    G SG +P  G+     A   +++K + 
Sbjct: 528 DSATAEPDSAPATSEGQDKGCRGTLPAQE----GPSGSKPLRGSLKEEVALDLSVRKPTA 583

Query: 270 PLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVE 308
                  ++    A   ++ DVP      S  PG+  ++
Sbjct: 584 EASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKID 622



 Score = 35.4 bits (80), Expect = 0.067
 Identities = 44/185 (23%), Positives = 62/185 (33%), Gaps = 20/185 (10%)

Query: 129 LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAP 188
           L +   Q P +P     + P P    AP PAP+P     P   P      AP     P  
Sbjct: 325 LRQQAAQAPYIPPLGLDAYPYPS---APLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYA 381

Query: 189 APAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISG 248
               +   A     +P     P       A PQ  A Q A Q     +P ++ +      
Sbjct: 382 RDDLSLYGA-----SPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPV------ 430

Query: 249 RPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVE 308
           RPA      +   +  K+   P +S+       S P     D P PC  P+  P     +
Sbjct: 431 RPAQEAEEKTWLPSCRKEKLQPRLSE------HSGPPIVIRDSPVPCTPPALPPCARECQ 484

Query: 309 QTPRK 313
             P+K
Sbjct: 485 SLPQK 489



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 38/124 (30%), Positives = 49/124 (39%), Gaps = 23/124 (18%)

Query: 195 VAAPAPAPA------PAPAPAPA-PAPAPDAAPQESAEQGANQGQR--GQEPLADQLHSG 245
           +  PAP PA      P  APAP  PAP P + P          G R   Q+PL+    S 
Sbjct: 656 ILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGP---------IGLRILAQQPLSVTCFSL 706

Query: 246 ISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVG 305
               P A   A+ A   A      P  +   A      P  +   V  P P+ ++APG  
Sbjct: 707 ALPSPPAVAVASPAPAPA----PSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPG-D 761

Query: 306 SVEQ 309
           S+EQ
Sbjct: 762 SLEQ 765


>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
          Length = 1711

 Score = 89.4 bits (220), Expect = 4e-18
 Identities = 55/119 (46%), Positives = 60/119 (50%), Gaps = 10/119 (8%)

Query: 103 LLAPRPVAVAVAVS-PPLE----PAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPA 157
           L AP P  ++V VS PPL     P   S   L  AP   P V  P PASTPP     APA
Sbjct: 297 LSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTP-VLAPMPASTPPA----APA 351

Query: 158 PAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAP 216
           P   P P   P + P +   L PA AP P PAP PAP+  PAP P PA  PA  P  AP
Sbjct: 352 PPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAP 410



 Score = 89.0 bits (219), Expect = 5e-18
 Identities = 68/173 (39%), Positives = 74/173 (42%), Gaps = 52/173 (30%)

Query: 104 LAPRPVAVAV-AVSPPLEPAAESLDGLEEAPEQLP-------------SVPVPAPASTPP 149
           L P  VA +V A SPPL P    +  L  AP  +P             SV VP PAS PP
Sbjct: 236 LVPVQVATSVPAPSPPLAP----VPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPP 291

Query: 150 --PVPVLAPAPAPAPAPVAAP----------------VAAPVAVAVLAPAPAPAPAPAPA 191
             PVP+ APAPAP   PV+AP                V APV   VLAP PA  P  APA
Sbjct: 292 SGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPA 351

Query: 192 PAPVAAPAP----------------APAPAPAPAPAPAPAPDAAPQESAEQGA 228
           P  V  P P                AP P PAP PAP   P   P  +A   A
Sbjct: 352 PPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAA 404



 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 67/220 (30%), Positives = 84/220 (38%), Gaps = 52/220 (23%)

Query: 115 VSPPLEPAAESLDGLEEAPEQLPSVPVPAP----------ASTPPPVPVLAPAPAPAPAP 164
           + PP   +A     + +A +   SVP P P           S P P P LAP PA APAP
Sbjct: 203 ICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAP 262

Query: 165 VAAPVAAP------VAVAVLAPAPA------PAPAPAPAPAPVAAPAPAP------APAP 206
            + P          V+ +VL P PA      P P  APAPAP++ P  AP      AP P
Sbjct: 263 PSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVP 322

Query: 207 APAP----APAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGA 262
             AP    AP P P  AP  ++   A                     PA  +        
Sbjct: 323 PSAPTLVLAPVPTPVLAPMPASTPPA--------------------APAPPSVPMPTPTP 362

Query: 263 AIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAP 302
           +    S P +   FA     AP  +    PAP P P+A P
Sbjct: 363 SSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATP 402



 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 44/108 (40%), Positives = 49/108 (45%), Gaps = 22/108 (20%)

Query: 102 LLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPA 161
           L+LAP P  V   +     PAA        AP  +P +P P P+S PP  P L PA AP 
Sbjct: 328 LVLAPVPTPVLAPMPASTPPAAP-------APPSVP-MPTPTPSSGPPSTPTLIPAFAPT 379

Query: 162 PAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 209
           P P              AP PAP   PAP P P A PA  P  AP PA
Sbjct: 380 PVP--------------APTPAPIFTPAPTPMPAATPAAIPTSAPIPA 413



 Score = 68.6 bits (166), Expect = 7e-12
 Identities = 55/185 (29%), Positives = 78/185 (42%), Gaps = 26/185 (14%)

Query: 138 SVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAA 197
           ++P+     +P P P+  PAP  A  P + P A  V ++V    PAP P     P  VA 
Sbjct: 188 TLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSV----PAPVPHSGLVPVQVAT 243

Query: 198 PAPAPAPAPAPAPAPAPAPDAAPQESAEQG-------------ANQGQRGQEPLA----D 240
             PAP+P  AP PA APAP + P   ++               A+    G  PL+     
Sbjct: 244 SVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPA 303

Query: 241 QLHSGISGRPAA---GTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPS 297
            L   +S  P A        SA    +  +  P+++   A    +AP   S  VP P P+
Sbjct: 304 PLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPS--VPMPTPT 361

Query: 298 PSAAP 302
           PS+ P
Sbjct: 362 PSSGP 366



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 32/116 (27%), Positives = 48/116 (41%), Gaps = 22/116 (18%)

Query: 144 PASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAP-APAPAPAPAPVAAPAPAP 202
           P ++P       PAP   P P+ A  +   A A + P P P  PAP+ + AP   P PA 
Sbjct: 527 PCTSPSGSTTTQPAPDGVPGPL-ADTSLVTASAKVLPTPQPLLPAPSGSSAP---PHPAK 582

Query: 203 AP--------------APAPAPAPAPAPDAAPQESAEQG---ANQGQRGQEPLADQ 241
            P              +P  +P       A+P E +E     +++  R + PL +Q
Sbjct: 583 MPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQ 638



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 35/134 (26%), Positives = 44/134 (32%), Gaps = 8/134 (5%)

Query: 177 VLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAP---QESAEQGANQGQR 233
           +LA      P     P      +P PAP   PAP  A  P + P   Q      A     
Sbjct: 175 ILATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHS 234

Query: 234 GQEPLADQLHSGISGRPAAGTAAASANGAAIKKL---SGPLISDFFAKRKRSAPEKSSGD 290
           G  P+           P A   A +    ++  L   S PL           A    SG 
Sbjct: 235 GLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGP 294

Query: 291 VP--APCPSPSAAP 302
           VP  AP P+P + P
Sbjct: 295 VPLSAPAPAPLSVP 308


>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
          Length = 1271

 Score = 88.2 bits (217), Expect = 9e-18
 Identities = 52/131 (39%), Positives = 62/131 (47%), Gaps = 17/131 (12%)

Query: 107 RPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVL----APAPAPAP 162
           R  A A   +PP +    +     E+PE  P  P P P   PPP P L    +P P P P
Sbjct: 3   RGAAAAQGTAPPQDGEQPA-----ESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEP 57

Query: 163 APVAAPVAAPVAVAVLA--------PAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAP 214
            P  AP   P A +  A        P PA  PA  PAP P   PAP PA  PAP PAP P
Sbjct: 58  CPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEP 117

Query: 215 APDAAPQESAE 225
           A ++AP+ + E
Sbjct: 118 ATESAPEPTPE 128



 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 46/132 (34%), Positives = 56/132 (42%), Gaps = 12/132 (9%)

Query: 106 PRPVAVAVAVSPPL-EPAAESLDG-----LEEAPEQLPSVPVPAPASTPPPVPVLAPAPA 159
           P P  ++ A   P+ EP  E   G       E+  +L + P P PA+ P   P   PA  
Sbjct: 41  PAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATE 100

Query: 160 PAPAPVAAPVAAPVAVAVLAPAPAPAPAPA----PAPAPVAAPAPAP--APAPAPAPAPA 213
           PAP P   P   P        AP P P PA    P PAP   P  AP  AP P P P   
Sbjct: 101 PAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTE 160

Query: 214 PAPDAAPQESAE 225
            AP+  P+ + E
Sbjct: 161 LAPEFCPEAAPE 172



 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 44/107 (41%), Positives = 50/107 (46%), Gaps = 4/107 (3%)

Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQ-LPSVPVPAPASTPPPVPVLAPAPAPAPA 163
           AP P A   A  P  EPA ES    E  PE  L SVP PAP  TP   P LAP P P P 
Sbjct: 102 APEP-ATEPAPEPAPEPATESAP--EPTPEPALESVPEPAPELTPEVAPELAPEPTPEPV 158

Query: 164 PVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAP 210
              AP   P A     P+PAP     P          +P+P+P+P+P
Sbjct: 159 TELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSP 205



 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 49/143 (34%), Positives = 59/143 (41%), Gaps = 20/143 (13%)

Query: 105 APRPV---AVAVAVSPPLEPAAESLDGLEEAPEQLP-----SVPVPAPASTPPPVPVLAP 156
           +P P+      +A  P  E  +ES   L   P   P     S P P PA+ P P P   P
Sbjct: 50  SPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEP 109

Query: 157 APAPAPAPV--AAPVAAPVAVAVLAPAPAP----------APAPAPAPAPVAAPAPAPAP 204
           AP PAP P   +AP   P       P PAP          AP P P P    AP   P  
Sbjct: 110 APEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEA 169

Query: 205 APAPAPAPAPAPDAAPQESAEQG 227
           AP   P+PAP     P ++ E+G
Sbjct: 170 APEFRPSPAPCLLQCPVDTRERG 192



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 49/140 (35%), Positives = 56/140 (40%), Gaps = 8/140 (5%)

Query: 81  EVDSDSVPAFYRETVQVGRCRLLLAPRPV-AVAVAVSPPLEPAAESLDGLEEAPEQLPS- 138
           E  S+S    Y E            P P  A   A  P  EPA E     E A E  P  
Sbjct: 68  EATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAP--EPATESAPEP 125

Query: 139 VPVPAPASTPPPVPVLAPAPAP--APAPVAAPVA--APVAVAVLAPAPAPAPAPAPAPAP 194
            P PA  S P P P L P  AP  AP P   PV   AP      AP   P+PAP     P
Sbjct: 126 TPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCP 185

Query: 195 VAAPAPAPAPAPAPAPAPAP 214
           V         +P+P+P+P+P
Sbjct: 186 VDTRERGLKTSPSPSPSPSP 205



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 48/174 (27%), Positives = 58/174 (33%), Gaps = 41/174 (23%)

Query: 143 APASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAP------APAPAPAPVA 196
           A   T PP     PA +P P P   P   P       PAP PAP      +P P P P  
Sbjct: 7   AAQGTAPPQDGEQPAESPEPPPPWPPPPPP-------PAPPPAPPLLSEASPEPIPEPCP 59

Query: 197 APAPAPAP------------APAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHS 244
             AP P P             P P PA  PA + AP+ + E          EP  +    
Sbjct: 60  ELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEP-------APEPATE---- 108

Query: 245 GISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSP 298
                PA   A   A  +A +    P +           PE +    P P P P
Sbjct: 109 -----PAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEP 157



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 32/116 (27%), Positives = 45/116 (38%), Gaps = 5/116 (4%)

Query: 184 PAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLH 243
           PA +P P P P   P P PAP PAP      +P+  P+   E             A +L+
Sbjct: 20  PAESPEPPP-PWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELY 78

Query: 244 SGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPS 299
           +  +  PA   A+  A   A +    P            APE ++   P P P P+
Sbjct: 79  TEPTPEPATEPASEPAPEPATEPAPEPATE----PAPEPAPEPATESAPEPTPEPA 130


>gi|4503519 eukaryotic translation initiation factor 3, subunit 5
           epsilon, 47kDa [Homo sapiens]
          Length = 357

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 46/84 (54%), Positives = 50/84 (59%), Gaps = 4/84 (4%)

Query: 137 PSVPVPAPASTPPPVPVLAPA--PAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAP 194
           P+VPV AP +TP PVP  APA  PAP PAP AAPV A    +   PA A A   AP   P
Sbjct: 4   PAVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQTP 63

Query: 195 VAAPAPAPAPAPA-PAPA-PAPAP 216
            +A APA  PAPA P PA P P P
Sbjct: 64  ASAQAPAQTPAPALPGPALPGPFP 87



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 35/75 (46%), Positives = 40/75 (53%), Gaps = 6/75 (8%)

Query: 149 PPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAP 208
           P VPV AP   P P P AAP + P      AP PAPA AP PA AP ++  PA A A   
Sbjct: 4   PAVPVSAPPATPTPVPAAAPASVP------APTPAPAAAPVPAAAPASSSDPAAAAAATA 57

Query: 209 APAPAPAPDAAPQES 223
           AP   PA   AP ++
Sbjct: 58  APGQTPASAQAPAQT 72



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 33/61 (54%), Positives = 37/61 (60%)

Query: 163 APVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQE 222
           A  A PV+AP A     PA APA  PAP PAP AAP PA APA +  PA A A  AAP +
Sbjct: 2   ATPAVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQ 61

Query: 223 S 223
           +
Sbjct: 62  T 62



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 32/62 (51%), Positives = 34/62 (54%)

Query: 159 APAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDA 218
           A    PV+AP A P  V   APA  PAP PAPA APV A APA +  PA A A   AP  
Sbjct: 2   ATPAVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQ 61

Query: 219 AP 220
            P
Sbjct: 62  TP 63



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 31/60 (51%), Positives = 33/60 (55%)

Query: 171 APVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQ 230
           A  AV V AP   P P PA APA V AP PAPA AP PA APA + D A   +A     Q
Sbjct: 2   ATPAVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQ 61



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 29/57 (50%), Positives = 32/57 (56%)

Query: 176 AVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQ 232
           AV   AP   P P PA AP + PAP PAPA AP PA APA  + P  +A   A  GQ
Sbjct: 5   AVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQ 61



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 30/67 (44%), Positives = 34/67 (50%), Gaps = 3/67 (4%)

Query: 178 LAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQR---G 234
           +A    P  AP   P PV A APA  PAP PAPA AP P AAP  S++  A        G
Sbjct: 1   MATPAVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPG 60

Query: 235 QEPLADQ 241
           Q P + Q
Sbjct: 61  QTPASAQ 67



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 32/108 (29%), Positives = 37/108 (34%), Gaps = 22/108 (20%)

Query: 189 APAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISG 248
           A    PV+AP   P P PA APA  PAP  AP  +    A                  S 
Sbjct: 2   ATPAVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPAS--------------SS 47

Query: 249 RPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCP 296
            PAA  AA +A G        P         +  AP      +P P P
Sbjct: 48  DPAAAAAATAAPGQTPASAQAP--------AQTPAPALPGPALPGPFP 87



 Score = 29.6 bits (65), Expect = 3.7
 Identities = 24/61 (39%), Positives = 27/61 (44%), Gaps = 10/61 (16%)

Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPA-PAPA 163
           AP P A   + S P   AA +      AP Q P+    APA TP P     P PA P P 
Sbjct: 36  APVPAAAPASSSDPAAAAAATA-----APGQTPA-SAQAPAQTPAPA---LPGPALPGPF 86

Query: 164 P 164
           P
Sbjct: 87  P 87


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 80.1 bits (196), Expect = 2e-15
 Identities = 72/212 (33%), Positives = 91/212 (42%), Gaps = 32/212 (15%)

Query: 104  LAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPS-VPVPAPASTPPPVPVLAPAP---- 158
            LAP   + +V+ S P   +A ++     AP   P+  P+ A  STP  V +LA A     
Sbjct: 1806 LAPVSASASVSASVPASTSAAAITS-SSAPASAPAPTPILASVSTPASVTILASASIPIL 1864

Query: 159  --------APAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAP 210
                    AP PAP A+  AAPV  A   PA AP  +   APA  +APAPAP P  AP P
Sbjct: 1865 ASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNP 1924

Query: 211  APAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGP 270
            AP PAP       A+  A   +  Q PL  Q  S  S +P       SA          P
Sbjct: 1925 AP-PAP-------AQTQAQTHKPVQNPL--QTTSQSSKQPPPSIRLPSA--------QTP 1966

Query: 271  LISDFFAKRKRSAPEKSSGDVPAPCPSPSAAP 302
              +D+ A  K     +S G + A       AP
Sbjct: 1967 NGTDYVASGKSIQTPQSHGTLTAELWDNKVAP 1998



 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 71/213 (33%), Positives = 88/213 (41%), Gaps = 16/213 (7%)

Query: 98   GRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPV-LAP 156
            GR +    P   A   A       ++ S+  L  AP   PS     PAST  P+P  L P
Sbjct: 1718 GRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLP-PSTSASVPASTSAPLPATLTP 1776

Query: 157  APAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPA------PAP 210
             PA   APV A   APV  +  AP PA   AP  A A V+A  PA   A A      PA 
Sbjct: 1777 VPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPAS 1836

Query: 211  APAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGP 270
            APAP P  A   +              LA  L S      +A T A +A+  A   ++ P
Sbjct: 1837 APAPTPILASVSTPASVTILASASIPILASALAS-----TSAPTPAPAASSPAAPVITAP 1891

Query: 271  LI-SDFFAKRKRSAPEKSSGDVPAPCPSPSAAP 302
             I +         AP  +S   PAP P+P +AP
Sbjct: 1892 TIPASAPTASVPLAPASASA--PAPAPTPVSAP 1922



 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 66/199 (33%), Positives = 78/199 (39%), Gaps = 13/199 (6%)

Query: 105  APRPVAVAVAVSPPLEPAAE-SLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPA 163
            A    +V    S PL P+   S+     AP      PVPA  S P P   LAP  A   A
Sbjct: 1740 AQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSA 1799

Query: 164  PVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQES 223
            PV A   APV+ +    A  PA   A A    +APA APAP P  A    PA       +
Sbjct: 1800 PVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASA 1859

Query: 224  AEQGANQGQRGQEPLADQL--HSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKR 281
            +             LA  L   S  +  PAA + AA    A     S P  S   A    
Sbjct: 1860 S----------IPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASA 1909

Query: 282  SAPEKSSGDVPAPCPSPSA 300
            SAP  +   V AP P+P A
Sbjct: 1910 SAPAPAPTPVSAPNPAPPA 1928



 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 55/198 (27%), Positives = 72/198 (36%), Gaps = 11/198 (5%)

Query: 84   SDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEP---AAESLDGLEEAPEQLPSVP 140
            S SVPA               AP P  +  +VS P      A+ S+  L  A     S P
Sbjct: 1816 SASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALAST-SAP 1874

Query: 141  VPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPA-------PAPAPAPA 193
             PAPA++ P  PV+     PA AP A+   AP + +  APAP P        PAPA   A
Sbjct: 1875 TPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQA 1934

Query: 194  PVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAG 253
                P   P    + +    P     P      G +    G+     Q H  ++      
Sbjct: 1935 QTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDN 1994

Query: 254  TAAASANGAAIKKLSGPL 271
              A  A    I K  GP+
Sbjct: 1995 KVAPPAVLNDISKKLGPI 2012


>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
          Length = 887

 Score = 78.2 bits (191), Expect = 9e-15
 Identities = 67/174 (38%), Positives = 79/174 (45%), Gaps = 19/174 (10%)

Query: 71  LRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVS------PPLEPAAE 124
           ++GPG++      S S PA      Q+   +    P PV V  +VS      PP      
Sbjct: 416 VKGPGKMS----HSSSGPA---SVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLP 468

Query: 125 SLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAP 184
           S  G   +    P    P  A +P   P  A A   A A  AA  AA  A A  APAPA 
Sbjct: 469 SSSGKISSGNSFP----PQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAA--APAPAL 522

Query: 185 APAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPL 238
           A A APA A  AAPA A A APAPAPA APA  AAP  +A    +  Q+   PL
Sbjct: 523 AAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPL 576



 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 56/172 (32%), Positives = 71/172 (41%), Gaps = 28/172 (16%)

Query: 143 APASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAP 202
           A A+   P P LA A APA A  AAP  A  A    APA APA A APA A  AAP+ + 
Sbjct: 511 AAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQ 570

Query: 203 APAPAPAPAPAPAPDAAPQESAEQ--GANQGQRGQEPL-ADQLHSGISGRPAAGT----- 254
            P+     A  P P A P     +   A Q + G   L A  +   + G  A G+     
Sbjct: 571 KPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPV 630

Query: 255 --------AAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSP 298
                   A A  +G+ ++   GPL            P+   G V A  P+P
Sbjct: 631 QAPGSGAPAPAGISGSDLQSSGGPL------------PDARPGAVQASSPAP 670



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 35/145 (24%), Positives = 55/145 (37%), Gaps = 7/145 (4%)

Query: 162 PAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQ 221
           P  ++   + P +V+ L+    P       P PV   +          P     P ++ +
Sbjct: 419 PGKMSHSSSGPASVSQLSSWKTPEQ-----PDPVWVQSSVSGKGEKHPPPRTQLPSSSGK 473

Query: 222 ESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKR 281
            S+       Q G  PL     S  +   AA  AAA+A  AA      P ++   A    
Sbjct: 474 ISSGNSFPPQQAGS-PLKRPF-SAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALA 531

Query: 282 SAPEKSSGDVPAPCPSPSAAPGVGS 306
           +A   +     AP P+P+AAP V +
Sbjct: 532 AAAAPALAAAAAPAPAPAAAPAVAA 556



 Score = 28.5 bits (62), Expect = 8.2
 Identities = 21/63 (33%), Positives = 25/63 (39%), Gaps = 3/63 (4%)

Query: 103 LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPE---QLPSVPVPAPASTPPPVPVLAPAPA 159
           LL   P      + P  +PA  SL G  + P+   QLPSV         PP   L P   
Sbjct: 744 LLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQLQPQWQ 803

Query: 160 PAP 162
           P P
Sbjct: 804 PKP 806


>gi|19111150 angiomotin isoform 2 [Homo sapiens]
          Length = 675

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 48/115 (41%), Positives = 53/115 (46%), Gaps = 2/115 (1%)

Query: 103 LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVP--VPAPASTPPPVPVLAPAPAP 160
           ++A  PVAVA A +P    A         A    P+    +PA AS      V   A A 
Sbjct: 498 MVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAA 557

Query: 161 APAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 215
           A   VA    APV    L P PAPA A A APA   AP  APA AP PAP P PA
Sbjct: 558 AAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPA 612



 Score = 76.3 bits (186), Expect = 3e-14
 Identities = 57/143 (39%), Positives = 64/143 (44%), Gaps = 26/143 (18%)

Query: 106 PRPVAVAVAVSPPLEPAAE-SLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPA- 163
           P PVA A   +     AA  +   +  AP  + +   PA A+ P P    A A A +PA 
Sbjct: 475 PAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAA 534

Query: 164 ----PVAAPVA------------APVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPA---- 203
               P AA VA            A V VA  APAP PAPA  P PAP AA A APA    
Sbjct: 535 AGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQA 594

Query: 204 ----PAPAPAPAPAPAPDAAPQE 222
               PA AP PAP P P  A  E
Sbjct: 595 PTSAPAVAPTPAPTPTPAVAQAE 617



 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 61/208 (29%), Positives = 76/208 (36%), Gaps = 41/208 (19%)

Query: 134 EQLPSVPVPAPASTP---------------------PPVPVLAPAPAPAPAPVAAPVAAP 172
           E +PS P P P STP                           A AP   PAPVAA   A 
Sbjct: 426 EYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAA 485

Query: 173 VAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQ 232
              A  A       A AP  A  AA APA A AP+PA A A A   +P  +         
Sbjct: 486 AITATAATITTTMVAAAPV-AVAAAAAPAAAAAPSPATAAATAAAVSPAAA--------- 535

Query: 233 RGQEPLADQLHSGISGRPAAGTAA---------ASANGAAIKKLSGPLISDFFAKRKRSA 283
            GQ P A  + S  +  P+A  AA         A     A+  +  P  +   A  +  A
Sbjct: 536 -GQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQA 594

Query: 284 PEKSSGDVPAPCPSPSAAPGVGSVEQTP 311
           P  +    P P P+P+ A     V  +P
Sbjct: 595 PTSAPAVAPTPAPTPTPAVAQAEVPASP 622



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 56/192 (29%), Positives = 78/192 (40%), Gaps = 17/192 (8%)

Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAP 164
           A  P++V   V+     AA +          + + PV   A+     P  A AP+PA A 
Sbjct: 468 AVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAA---APAAAAAPSPATAA 524

Query: 165 VAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESA 224
             A   +P A   +  A + A A A AP+  AA A   APA APAP PAPA    P  +A
Sbjct: 525 ATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPA-APAPVPAPALVPVPAPAA 583

Query: 225 EQGANQGQRGQEPLADQLHSGISGRPAAGTA-----AASANGAAIKKLSGPLISDFFAKR 279
            Q +   Q      A  +    +  P    A     A+ A G    +LS P ++      
Sbjct: 584 AQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLT------ 637

Query: 280 KRSAPEKSSGDV 291
               P+K+ G V
Sbjct: 638 --CNPDKTDGPV 647


>gi|166064029 angiomotin isoform 1 [Homo sapiens]
          Length = 1084

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 48/115 (41%), Positives = 53/115 (46%), Gaps = 2/115 (1%)

Query: 103  LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVP--VPAPASTPPPVPVLAPAPAP 160
            ++A  PVAVA A +P    A         A    P+    +PA AS      V   A A 
Sbjct: 907  MVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAA 966

Query: 161  APAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 215
            A   VA    APV    L P PAPA A A APA   AP  APA AP PAP P PA
Sbjct: 967  AAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPA 1021



 Score = 76.3 bits (186), Expect = 3e-14
 Identities = 57/143 (39%), Positives = 64/143 (44%), Gaps = 26/143 (18%)

Query: 106  PRPVAVAVAVSPPLEPAAE-SLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPA- 163
            P PVA A   +     AA  +   +  AP  + +   PA A+ P P    A A A +PA 
Sbjct: 884  PAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAA 943

Query: 164  ----PVAAPVA------------APVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPA---- 203
                P AA VA            A V VA  APAP PAPA  P PAP AA A APA    
Sbjct: 944  AGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQA 1003

Query: 204  ----PAPAPAPAPAPAPDAAPQE 222
                PA AP PAP P P  A  E
Sbjct: 1004 PTSAPAVAPTPAPTPTPAVAQAE 1026



 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 61/208 (29%), Positives = 76/208 (36%), Gaps = 41/208 (19%)

Query: 134  EQLPSVPVPAPASTP---------------------PPVPVLAPAPAPAPAPVAAPVAAP 172
            E +PS P P P STP                           A AP   PAPVAA   A 
Sbjct: 835  EYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAA 894

Query: 173  VAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQ 232
               A  A       A AP  A  AA APA A AP+PA A A A   +P  +         
Sbjct: 895  AITATAATITTTMVAAAPV-AVAAAAAPAAAAAPSPATAAATAAAVSPAAA--------- 944

Query: 233  RGQEPLADQLHSGISGRPAAGTAA---------ASANGAAIKKLSGPLISDFFAKRKRSA 283
             GQ P A  + S  +  P+A  AA         A     A+  +  P  +   A  +  A
Sbjct: 945  -GQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQA 1003

Query: 284  PEKSSGDVPAPCPSPSAAPGVGSVEQTP 311
            P  +    P P P+P+ A     V  +P
Sbjct: 1004 PTSAPAVAPTPAPTPTPAVAQAEVPASP 1031



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 56/192 (29%), Positives = 78/192 (40%), Gaps = 17/192 (8%)

Query: 105  APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAP 164
            A  P++V   V+     AA +          + + PV   A+     P  A AP+PA A 
Sbjct: 877  AVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAA---APAAAAAPSPATAA 933

Query: 165  VAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESA 224
              A   +P A   +  A + A A A AP+  AA A   APA APAP PAPA    P  +A
Sbjct: 934  ATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPA-APAPVPAPALVPVPAPAA 992

Query: 225  EQGANQGQRGQEPLADQLHSGISGRPAAGTA-----AASANGAAIKKLSGPLISDFFAKR 279
             Q +   Q      A  +    +  P    A     A+ A G    +LS P ++      
Sbjct: 993  AQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLT------ 1046

Query: 280  KRSAPEKSSGDV 291
                P+K+ G V
Sbjct: 1047 --CNPDKTDGPV 1056


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 49/140 (35%), Positives = 59/140 (42%), Gaps = 25/140 (17%)

Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAP 164
           AP P     + SP L PAAE                 PAP + PPP P L   P+P  AP
Sbjct: 516 APTPGVPTGSPSPDLAPAAE-----------------PAPGAAPPPPPPLPGLPSPQEAP 558

Query: 165 VAAPVAAPVAVAVLAPAPAP------APAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDA 218
            +AP  AP       P PAP       P P P P P     P P P P P P P   PDA
Sbjct: 559 PSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDA 618

Query: 219 APQESAEQGANQGQRGQEPL 238
             +  +E G   G + ++P+
Sbjct: 619 LGRRDSELG--PGVKAKKPI 636



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 47/162 (29%), Positives = 59/162 (36%), Gaps = 6/162 (3%)

Query: 145 ASTPPPVPVLAPAPAPA-PAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPA 203
           AS  PP P  AP  AP  P+ +   V       ++     P  A +    PVA   P+  
Sbjct: 455 ASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGG 514

Query: 204 PAPAP-APAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGA 262
            AP P  P  +P+PD AP      GA        P    L S     P+A   A    G+
Sbjct: 515 DAPTPGVPTGSPSPDLAPAAEPAPGA---APPPPPPLPGLPSPQEAPPSAPPQAPPLPGS 571

Query: 263 AIKKLSGPLISDFFAKRKRSAPEK-SSGDVPAPCPSPSAAPG 303
                + PL  D         P   + G VP P P P   PG
Sbjct: 572 PEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPG 613



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 45/138 (32%), Positives = 57/138 (41%), Gaps = 14/138 (10%)

Query: 91  YRETVQVGRCRLLLAPRPVAVAVAVSPP-LEPAAESLDGLEEAPEQLPSVPVPAPASTPP 149
           + E+  +G  R    P     A    P  LE   E L+  E+   ++   P  A +    
Sbjct: 447 FSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELE--EKGLIRILRGPGDAVSIEIL 504

Query: 150 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPA---PAPAPAPVAAPAPAPAPAP 206
           PV V  P+   AP P   P  +P     LAPA  PAP    P P P P   P+P  AP  
Sbjct: 505 PVAVATPSGGDAPTP-GVPTGSPSPD--LAPAAEPAPGAAPPPPPPLP-GLPSPQEAPPS 560

Query: 207 APAPAP----APAPDAAP 220
           AP  AP    +P P  AP
Sbjct: 561 APPQAPPLPGSPEPPPAP 578


>gi|33286436 gametogenetin [Homo sapiens]
          Length = 652

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 59/161 (36%), Positives = 74/161 (45%), Gaps = 9/161 (5%)

Query: 107 RPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVA 166
           RP    +A    + PA  + + +   P  L  +P P P  TPPP  +  PA  P P PVA
Sbjct: 405 RPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELP-PLPPPTPPPT-LQPPALQPTPLPVA 462

Query: 167 APVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA----PAPAPAPDAAPQE 222
            P+   +     A AP  APA  PA A   APAP+PAPAP  A    P  APAP AAP +
Sbjct: 463 PPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIK 522

Query: 223 SAEQGANQGQRGQEPLA--DQLHSGISGRPAAGTAAASANG 261
           +  +  N+G R        D LH       A  T   S+ G
Sbjct: 523 TRTR-RNKGSRAARGATRKDGLHGDGPRERATATVPDSSGG 562



 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 53/173 (30%), Positives = 67/173 (38%), Gaps = 14/173 (8%)

Query: 102 LLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAP----- 156
           LL  P  +  A     P+ P    L  L   P   P   +  PA  P P+PV  P     
Sbjct: 410 LLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGL 469

Query: 157 -----APAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA-- 209
                A AP  AP   P  A       +PAPAP  A  P+P PV+APAPA AP       
Sbjct: 470 GHKESALAPTAAPALPPALAADQAPAPSPAPAPTVA-EPSP-PVSAPAPAAAPIKTRTRR 527

Query: 210 PAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGA 262
              + A   A ++    G    +R    + D    G  G  A+ T AA+   A
Sbjct: 528 NKGSRAARGATRKDGLHGDGPRERATATVPDSSGGGGGGSGASQTGAANTRAA 580



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 59/217 (27%), Positives = 75/217 (34%), Gaps = 45/217 (20%)

Query: 123 AESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAP-------------- 168
           AE  DG  E     PS P     + PPP     P   P    V+AP              
Sbjct: 312 AEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGG 371

Query: 169 -VAAP--VAVAVLAPAPAPAPAP----------APAPAPVAAPA---PAPAPAPAPAPAP 212
            + AP   A A+  P  +P P P           PAPA +A P    PAP       P P
Sbjct: 372 GIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGP 431

Query: 213 ------APAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAA-GTAAASANGAAIK 265
                  P P   P  + +  A Q      P+A  L  G+  + +A    AA A   A+ 
Sbjct: 432 PGLQELPPLPPPTPPPTLQPPALQPT--PLPVAPPLTPGLGHKESALAPTAAPALPPALA 489

Query: 266 KLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAP 302
               P      A     AP  +    P   P+P+AAP
Sbjct: 490 ADQAP------APSPAPAPTVAEPSPPVSAPAPAAAP 520



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 67/255 (26%), Positives = 86/255 (33%), Gaps = 57/255 (22%)

Query: 108 PVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVP--VLAPAPAPAPAPV 165
           P  + V   P   P+   L  LE     +P     A  S PPP P   L P P+    P 
Sbjct: 57  PPGLMVPREPQASPSTLPLT-LERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPA 115

Query: 166 AAPV--------------AAPVAVAVLAPAPAP-----------APAPAPAPAPVAAPAP 200
             PV                P ++  L P P P           AP+  P P     P P
Sbjct: 116 GTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPP 175

Query: 201 APAPAPAPAP---APAPAPDAAPQESAEQG-ANQGQR------GQEPLADQ--------L 242
                  PA     PA A  A+P   ++ G  NQGQ       G  P A +         
Sbjct: 176 PLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADS 235

Query: 243 HSGIS--------GRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAP 294
            SG+S         RP+    AAS++ AA   L G      FA     +  +     P P
Sbjct: 236 ESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLP 295

Query: 295 CPSPSAAPGVGSVEQ 309
              P AA  +G V +
Sbjct: 296 ---PGAARPLGEVSR 307



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 21/69 (30%), Positives = 28/69 (40%)

Query: 144 PASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPA 203
           P S  PP  ++   P  +P+ +   +  P  V       A   AP PAPA    P P+  
Sbjct: 52  PGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKW 111

Query: 204 PAPAPAPAP 212
             PA  P P
Sbjct: 112 QKPAGTPVP 120


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 55/157 (35%), Positives = 62/157 (39%), Gaps = 18/157 (11%)

Query: 112 AVAVSPPLEPAAESLDGLEEAPEQLPSV-----PVPAPASTPPPVPVLAPAPAPAPAPVA 166
           A  V PP   A         AP   P+      P P PA  PPP PV A APA AP   A
Sbjct: 96  AARVQPPRRGATPPAP--PRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAA 153

Query: 167 APVAAPVAVAVLAP-----------APAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 215
           A   AP +     P           AP PAPA  PA AP A P  AP PA A    P P 
Sbjct: 154 AAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPP 213

Query: 216 PDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAA 252
           P   P    +Q     Q    P    + +G + RP +
Sbjct: 214 PPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVS 250



 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 51/153 (33%), Positives = 57/153 (37%), Gaps = 31/153 (20%)

Query: 159 APAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDA 218
           A  PAP  AP  AP A A  AP P PAP P PAP   AAPA AP  A A A AP     A
Sbjct: 106 ATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPA 165

Query: 219 APQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAK 278
            P   A++ A                     P A    A A   A+   +GP        
Sbjct: 166 QPGPRAQRAA---------------------PLAAPPPAPAAPPAVAPPAGP-------- 196

Query: 279 RKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTP 311
             R AP  +      P P P   P     +Q P
Sbjct: 197 --RRAPPPAVAAREPPLPPPPQPPAPPQQQQPP 227



 Score = 65.9 bits (159), Expect = 5e-11
 Identities = 47/124 (37%), Positives = 50/124 (40%), Gaps = 12/124 (9%)

Query: 105 APR--PVAVAVAVSPPLE-----PAAESLDGLEEAPEQLPSV----PVPAPASTPPPVPV 153
           APR  P A A A  PP       PA  +      AP    +     P P PA   P    
Sbjct: 114 APRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQR 173

Query: 154 LAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPA 213
            AP  AP PAP A P  AP A    AP PA A    P P P   PAP     P P P P 
Sbjct: 174 AAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPP-PQPQ 232

Query: 214 PAPD 217
           P P+
Sbjct: 233 PPPE 236



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 24/74 (32%), Positives = 26/74 (35%), Gaps = 5/74 (6%)

Query: 99  RCRLLLAPRPVAVAV-AVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPA 157
           R   L AP P   A  AV+PP  P       +      LP    P P    PP     P 
Sbjct: 173 RAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLP----PPPQPPAPPQQQQPPP 228

Query: 158 PAPAPAPVAAPVAA 171
           P P P P    V A
Sbjct: 229 PQPQPPPEGGAVRA 242


>gi|4757962 cyclin-dependent kinase inhibitor 1B [Homo sapiens]
          Length = 198

 Score = 75.1 bits (183), Expect = 8e-14
 Identities = 45/118 (38%), Positives = 60/118 (50%), Gaps = 19/118 (16%)

Query: 26  RTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPLRGPGRLQWTEVDSD 85
           + SACR+LFGPVDHEEL+R+L+    ++    Q +W++DFQ   PL   G+ +W EV+  
Sbjct: 25  KPSACRNLFGPVDHEELTRDLEKHCRDMEEASQRKWNFDFQNHKPLE--GKYEWQEVEKG 82

Query: 86  SVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPA 143
           S+P FY              PRP   A  V     PA ES D     P   P +  PA
Sbjct: 83  SLPEFYYR-----------PPRPPKGACKV-----PAQESQDVSGSRP-AAPLIGAPA 123


>gi|24307909 ral guanine nucleotide dissociation stimulator isoform
           1 [Homo sapiens]
          Length = 914

 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 53/134 (39%), Positives = 62/134 (46%), Gaps = 22/134 (16%)

Query: 124 ESLDGLEEAPEQLPSVPVPAP------ASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAV 177
           E  + +E  PE L  VP   P      A TP   P  +P PAPAP P  AP  AP +   
Sbjct: 249 EHSEPIEAEPEALSPVPALKPTPELELALTPARAP--SPVPAPAPEPEPAPTPAPGSELE 306

Query: 178 LAPAPAP----APAPA----PAPAPVAAPAPAPAPAPAPA------PAPAPAPDAAPQES 223
           +APAPAP    AP PA     APAP     PAP   PAP+      PAPAP P   P   
Sbjct: 307 VAPAPAPELQQAPEPAVGLESAPAPALELEPAPEQDPAPSQTLELEPAPAPVPSLQPSWP 366

Query: 224 AEQGANQGQRGQEP 237
           +   A  G   ++P
Sbjct: 367 SPVVAENGLSEEKP 380



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 48/147 (32%), Positives = 59/147 (40%), Gaps = 44/147 (29%)

Query: 164 PVAAPVAAPVAVAVLAPAPAP--APAPAPAPAPVAAPAPAPAPAPAPAP------APAPA 215
           P+ A   A   V  L P P    A  PA AP+PV APAP P PAP PAP      APAPA
Sbjct: 253 PIEAEPEALSPVPALKPTPELELALTPARAPSPVPAPAPEPEPAPTPAPGSELEVAPAPA 312

Query: 216 PDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDF 275
           P+   Q++ E                        PA G  +A A    ++          
Sbjct: 313 PEL--QQAPE------------------------PAVGLESAPAPALELEP--------- 337

Query: 276 FAKRKRSAPEKSSGDVPAPCPSPSAAP 302
            A  +  AP ++    PAP P PS  P
Sbjct: 338 -APEQDPAPSQTLELEPAPAPVPSLQP 363



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 39/99 (39%), Positives = 44/99 (44%), Gaps = 15/99 (15%)

Query: 105 APRPVAVAVAVSPPLEPAAESLDG--LEEAPEQLPSV---PVPAPASTPPPVPVLAPAPA 159
           AP PV    A +P  EPA     G  LE AP   P +   P PA      P P L   PA
Sbjct: 282 APSPVP---APAPEPEPAPTPAPGSELEVAPAPAPELQQAPEPAVGLESAPAPALELEPA 338

Query: 160 PAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA-PAPVAA 197
           P   P      AP     L PAPAP P+  P+ P+PV A
Sbjct: 339 PEQDP------APSQTLELEPAPAPVPSLQPSWPSPVVA 371


>gi|108796058 ral guanine nucleotide dissociation stimulator isoform
           2 [Homo sapiens]
          Length = 859

 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 53/134 (39%), Positives = 62/134 (46%), Gaps = 22/134 (16%)

Query: 124 ESLDGLEEAPEQLPSVPVPAP------ASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAV 177
           E  + +E  PE L  VP   P      A TP   P  +P PAPAP P  AP  AP +   
Sbjct: 194 EHSEPIEAEPEALSPVPALKPTPELELALTPARAP--SPVPAPAPEPEPAPTPAPGSELE 251

Query: 178 LAPAPAP----APAPA----PAPAPVAAPAPAPAPAPAPA------PAPAPAPDAAPQES 223
           +APAPAP    AP PA     APAP     PAP   PAP+      PAPAP P   P   
Sbjct: 252 VAPAPAPELQQAPEPAVGLESAPAPALELEPAPEQDPAPSQTLELEPAPAPVPSLQPSWP 311

Query: 224 AEQGANQGQRGQEP 237
           +   A  G   ++P
Sbjct: 312 SPVVAENGLSEEKP 325



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 48/147 (32%), Positives = 59/147 (40%), Gaps = 44/147 (29%)

Query: 164 PVAAPVAAPVAVAVLAPAPAP--APAPAPAPAPVAAPAPAPAPAPAPAP------APAPA 215
           P+ A   A   V  L P P    A  PA AP+PV APAP P PAP PAP      APAPA
Sbjct: 198 PIEAEPEALSPVPALKPTPELELALTPARAPSPVPAPAPEPEPAPTPAPGSELEVAPAPA 257

Query: 216 PDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDF 275
           P+   Q++ E                        PA G  +A A    ++          
Sbjct: 258 PEL--QQAPE------------------------PAVGLESAPAPALELEP--------- 282

Query: 276 FAKRKRSAPEKSSGDVPAPCPSPSAAP 302
            A  +  AP ++    PAP P PS  P
Sbjct: 283 -APEQDPAPSQTLELEPAPAPVPSLQP 308



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 39/99 (39%), Positives = 44/99 (44%), Gaps = 15/99 (15%)

Query: 105 APRPVAVAVAVSPPLEPAAESLDG--LEEAPEQLPSV---PVPAPASTPPPVPVLAPAPA 159
           AP PV    A +P  EPA     G  LE AP   P +   P PA      P P L   PA
Sbjct: 227 APSPVP---APAPEPEPAPTPAPGSELEVAPAPAPELQQAPEPAVGLESAPAPALELEPA 283

Query: 160 PAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA-PAPVAA 197
           P   P      AP     L PAPAP P+  P+ P+PV A
Sbjct: 284 PEQDP------APSQTLELEPAPAPVPSLQPSWPSPVVA 316


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 72.0 bits (175), Expect = 6e-13
 Identities = 58/151 (38%), Positives = 68/151 (45%), Gaps = 36/151 (23%)

Query: 102  LLLAPRPV-------AVAVAVSPPLEPAAESLDGLEEAPEQLPS-VPVPAPAS------- 146
            LLLAP           VA A SP L PA+        AP   P+   + APAS       
Sbjct: 1525 LLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALA 1584

Query: 147  TP------PPVPVLAPAPAP--APAPVAAPV--AAPVAVAVLAPAPAPAP---------- 186
            TP      P   +LAP+PAP  AP PV AP   AAPV  +   P P  AP          
Sbjct: 1585 TPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLAS 1644

Query: 187  -APAPAPAPVAAPAPAPAPAPAPAPAPAPAP 216
             +P PAP PV AP+      PAP P+P P+P
Sbjct: 1645 ASPVPAPTPVLAPSSTQTMLPAPVPSPLPSP 1675



 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 32/84 (38%), Positives = 39/84 (46%), Gaps = 1/84 (1%)

Query: 130  EEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPA 189
            E  P   P  P P PAS P  +P L P P  AP P++AP    +    + P+P P     
Sbjct: 2434 ERVPRPAPR-PRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIP 2492

Query: 190  PAPAPVAAPAPAPAPAPAPAPAPA 213
            P  +P   P PA  P PA  P PA
Sbjct: 2493 PCSSPACTPPPACTPPPAHTPPPA 2516



 Score = 65.1 bits (157), Expect = 8e-11
 Identities = 65/246 (26%), Positives = 95/246 (38%), Gaps = 29/246 (11%)

Query: 70   PLRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGL 129
            P   PGRL    + +   P     T  + R  L L   P     A +P   P   S    
Sbjct: 1346 PTLTPGRLPTPTLGTARAPM---PTPTLVRPLLKLVHSPSPEVSASAPGAAPLTIS---- 1398

Query: 130  EEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPA 189
              +P  +PS  +P PAS+P P+P  +P  +P  + V+ P+++ + ++V      P   PA
Sbjct: 1399 --SPLHVPS-SLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISV------PTTLPA 1449

Query: 190  PAPAPVAAPAPAPAPAPAPAPA--PAPAPDAAPQESAEQG-ANQGQRGQEPLADQLHSGI 246
            PA AP+  P  AP    A  PA   +  P  AP   A  G  +    G  P A  L  G+
Sbjct: 1450 PASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGL 1509

Query: 247  SGRPAAGT----------AAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCP 296
            +  P+  +          A  S++   +     P  S         A    S   PAP  
Sbjct: 1510 ATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQ 1569

Query: 297  SPSAAP 302
            +   AP
Sbjct: 1570 ASLLAP 1575



 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 57/194 (29%), Positives = 76/194 (39%), Gaps = 28/194 (14%)

Query: 117  PPLEPAAESLDGLEEAPEQLPSVPVPAPASTPP--PVPVLAPAPAPAPAPVAAPVAAPVA 174
            PPL PA             LP+V  P P  TP   P P L  A AP P P    +  P+ 
Sbjct: 1325 PPLAPAPRP------PSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPT---LVRPLL 1375

Query: 175  VAVLAPAP-APAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQR 233
              V +P+P   A AP  AP  +++P   P+  P PA +P P P+++P  S          
Sbjct: 1376 KLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSST----- 1430

Query: 234  GQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPA 293
               PL+  L   +       T  A A+      +S PL          S P   +   P 
Sbjct: 1431 VSVPLSSSLPISV-----PTTLPAPASAPLTIPISAPLTV------SASGPALLTSVTPP 1479

Query: 294  PCPSPSAAPGVGSV 307
              P   AAPG  S+
Sbjct: 1480 LAPVVPAAPGPPSL 1493



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 43/130 (33%), Positives = 48/130 (36%), Gaps = 15/130 (11%)

Query: 105  APRPVAVAVAVSPPLEPAAESLDGLEEAP----EQLPSVPVPAPASTPPPVPVLAPAPAP 160
            A  P      VS  L  A     G    P     Q  S   P P  +P    V  PAP P
Sbjct: 2385 AKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTP-PRCSPARERVPRPAPRP 2443

Query: 161  APAPVAAPVAAPVAVAVLAPAPAPAPAP----------APAPAPVAAPAPAPAPAPAPAP 210
             P P +AP A P  V V   AP P  AP           P+P P +   P  +PA  P P
Sbjct: 2444 RPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPP 2503

Query: 211  APAPAPDAAP 220
            A  P P   P
Sbjct: 2504 ACTPPPAHTP 2513



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 36/84 (42%), Positives = 42/84 (50%), Gaps = 12/84 (14%)

Query: 141  VPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAP--------APAPAPAPAP 192
            VP PA  P P P  APA  PA  PV  PV+APV ++  AP P         P+P P    
Sbjct: 2436 VPRPAPRPRPTPASAPAAIPALVPV--PVSAPVPIS--APNPITILPVHILPSPPPPSQI 2491

Query: 193  APVAAPAPAPAPAPAPAPAPAPAP 216
             P ++PA  P PA  P PA  P P
Sbjct: 2492 PPCSSPACTPPPACTPPPAHTPPP 2515



 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 71/265 (26%), Positives = 86/265 (32%), Gaps = 77/265 (29%)

Query: 103  LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPS---VPVPAPASTP----------- 148
            + AP+   +A + +PPL P          AP    S   VPV AP+STP           
Sbjct: 1590 MAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVP 1649

Query: 149  PPVPVLAPAPAPA--PAPVAAPVAAPVAVAVLAPAPAPAP-------------------- 186
             P PVLAP+      PAPV +P+ +P +   LA APA AP                    
Sbjct: 1650 APTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQG 1709

Query: 187  -------------------------APAPAPAPVA----APAPAPAPAPAPAPAPAPAPD 217
                                     AP P   P      APAP  APA    PAPA    
Sbjct: 1710 PFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLT 1769

Query: 218  AAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFA 277
             AP  S+                 L    +  P  G AAA     A      P      A
Sbjct: 1770 LAPASSSASLLAPAS------VQTLTLSPAPVPTLGPAAAQTLALAPASTQSP------A 1817

Query: 278  KRKRSAPEKSSGDVPAPCPSPSAAP 302
             +  S    +SG  P P    S  P
Sbjct: 1818 SQASSLVVSASGAAPLPVTMVSRLP 1842



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 65/229 (28%), Positives = 79/229 (34%), Gaps = 60/229 (26%)

Query: 110  AVAVAVSPPLEPAAESLDGLEEAPEQLPS-------------VPVPAPASTPPPVPVLAP 156
            A+  +V+PPL P   +  G    P   PS                P+ +S+  P   L  
Sbjct: 1471 ALLTSVTPPLAPVVPAAPG---PPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLL 1527

Query: 157  APAPAPAPVAAPVAAPVAVAVLAPAPAPA-PAP-APAPAPVAAPAPAPAP---------- 204
            AP  +  P      AP    VL PA A A P P AP PAP  A   APA           
Sbjct: 1528 APTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPL 1587

Query: 205  -----------APAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAG 253
                       AP+PAP  AP P  AP   A       Q     +A       S  P   
Sbjct: 1588 APMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAP------SSTPGTS 1641

Query: 254  TAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAP 302
             A+AS   A    L               AP  +   +PAP PSP  +P
Sbjct: 1642 LASASPVPAPTPVL---------------APSSTQTMLPAPVPSPLPSP 1675



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 33/109 (30%), Positives = 44/109 (40%), Gaps = 4/109 (3%)

Query: 106  PRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPV 165
            PRP  V + V+  L+P  +  +G        P  P+      PPP P L+  P P P P 
Sbjct: 985  PRPKPVKMKVNRMLQPVPKQ-EGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQ 1043

Query: 166  AAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAP 214
              P +  V+ +   P   PA  P   P PV  P   P     P   P+P
Sbjct: 1044 VLPASLMVSASPAGPPLIPASRP---PGPVLLPPLQPNSGSLPQVLPSP 1089



 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 53/176 (30%), Positives = 68/176 (38%), Gaps = 30/176 (17%)

Query: 141  VPAPAST------PP--PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAP 192
            VP PA T      PP  P   L+ APAP  AP +    AP     LAPA + A   APA 
Sbjct: 1725 VPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPAS 1784

Query: 193  APVAAPAPAPAPAPAPAPAPAPA-PDAAPQESAEQGAN--QGQRGQEPLADQLHSGI--- 246
                  +PAP P   PA A   A   A+ Q  A Q ++      G  PL   + S +   
Sbjct: 1785 VQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVS 1844

Query: 247  ----------SGRPAAGTAAASANGAAIKKLSGP------LISDFFAKRKRSAPEK 286
                      SG P+  + A S  G   ++   P       +     KRKR   E+
Sbjct: 1845 KDEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPPRSPFYLDSLEEKRKRQRSER 1900



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 55/180 (30%), Positives = 69/180 (38%), Gaps = 30/180 (16%)

Query: 66   QQDMPLRGPGRLQWTEVDSDS-VPAFYRETVQVGRCRLLLAPRPVAV-------AVAVSP 117
            Q  +P+  P     T + S S VPA            +L AP P  +        +A++P
Sbjct: 1626 QTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAP 1685

Query: 118  PLEPAAESLDGLEEAPEQL-------PSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVA 170
             L P   +L G   +P Q        P  P P    +  P   L P PA   +    P  
Sbjct: 1686 ALAP---TLGG--SSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPL 1740

Query: 171  APVAVAVLAPAPAPAPA----PAPAPAPVAAPAPAPAPAPAPAP------APAPAPDAAP 220
             P     LAPAP  APA    PAPA     APA + A   APA       +PAP P   P
Sbjct: 1741 GPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGP 1800



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 37/116 (31%), Positives = 49/116 (42%), Gaps = 10/116 (8%)

Query: 102  LLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPA 161
            L+ A RP    +   PPL+P + SL      P+ LPS       ++ PP P L+  P P 
Sbjct: 1060 LIPASRPPGPVLL--PPLQPNSGSL------PQVLPSPLGVLSGTSRPPTPTLSLKPTP- 1110

Query: 162  PAPVA-APVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAP 216
            PAPV  +P   P + ++L P   P     P  A                PAP PAP
Sbjct: 1111 PAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAP 1166



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 38/153 (24%), Positives = 53/153 (34%), Gaps = 5/153 (3%)

Query: 117  PPLEPAAESLDGLEEAPEQLP-SVPVPAPASTP----PPVPVLAPAPAPAPAPVAAPVAA 171
            P   PA E +      P   P S P   PA  P     PVP+ AP P         P   
Sbjct: 2427 PRCSPARERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPP 2486

Query: 172  PVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQG 231
            P +      +PA  P PA  P P   P PA      P+      P + P  ++      G
Sbjct: 2487 PPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLG 2546

Query: 232  QRGQEPLADQLHSGISGRPAAGTAAASANGAAI 264
             R +  L  Q  +       A  A++  +  ++
Sbjct: 2547 LRPEAELCAQALASPESLELASVASSETSSLSL 2579



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 41/127 (32%), Positives = 50/127 (39%), Gaps = 18/127 (14%)

Query: 104  LAPR-PVAVAVAVSPPLEPAAESLDGLEEAPEQ-LPSVPVPAPASTPPPVPVLAPAPAPA 161
            LAP  PV  A A +  L PA+ S   L  A  Q L   P P P   P     LA APA  
Sbjct: 1754 LAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPAST 1813

Query: 162  PAP--------VAAPVAAPVAVAVLAPAPAPAPAP--------APAPAPVAAPAPAPAPA 205
             +P        V+A  AAP+ V +++  P     P         P+P   A     P P 
Sbjct: 1814 QSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPR 1873

Query: 206  PAPAPAP 212
              P P P
Sbjct: 1874 RQPPPPP 1880



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 39/131 (29%), Positives = 51/131 (38%), Gaps = 13/131 (9%)

Query: 106  PRPVAVAVAVSPPLEPAAESLDGLEEAPEQLP-SVPVPAPASTPPPVPVLAP-----APA 159
            PR     V V PP  P   +       P+ LP S+ V A  + PP +P   P      P 
Sbjct: 1015 PRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPP 1074

Query: 160  PAPAPVAAPVAAPVAVAVLA-----PAPAPAPAPAPAPAPV-AAPAPAPAPAPAPAPAPA 213
              P   + P   P  + VL+     P P  +  P P PAPV  +PAP P  +    P   
Sbjct: 1075 LQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTP-PAPVRLSPAPPPGSSSLLKPLTV 1133

Query: 214  PAPDAAPQESA 224
            P     P  +A
Sbjct: 1134 PPGYTFPPAAA 1144



 Score = 35.0 bits (79), Expect = 0.087
 Identities = 48/211 (22%), Positives = 73/211 (34%), Gaps = 34/211 (16%)

Query: 120  EPAAESLDG--LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAV 177
            + A +S +G  L   PE    +P+    S    +P  A +  P   P+ A   +      
Sbjct: 2622 QEAPDSAEGTTLTVLPEG-EELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEA 2680

Query: 178  LAPAPAPAPAPAPAPAPVAAPAPAPAPAPAP-APAPAPAPDAAPQESAE-QGANQGQRGQ 235
              P  +P        A VAAP+ + +   +P  P+PA  P        E +G   G+ GQ
Sbjct: 2681 KTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQ 2740

Query: 236  EPLADQLHSGISGR-------------------------PAAGTAAASANGAAIKKLSGP 270
             P    L   + GR                         P     +AS    +++ +SGP
Sbjct: 2741 PPGPKVLRK-LPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGP 2799

Query: 271  LISDFFAKRKRSAPEKSSGDVPAPCPSPSAA 301
              S        +AP   S  +P P   P  A
Sbjct: 2800 ESSPPIGGPCEAAP---SSSLPTPPQQPFIA 2827



 Score = 35.0 bits (79), Expect = 0.087
 Identities = 51/209 (24%), Positives = 64/209 (30%), Gaps = 42/209 (20%)

Query: 103  LLAPRPVAVAVAVSPPLEPAAESLD---GLEEAPEQL------PSVPVPAPASTPPPVPV 153
            LLA  P AV      P +      D   G++EAP          + PVP P +     PV
Sbjct: 2848 LLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPV 2907

Query: 154  LAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPA 213
            L P   P P P+                P P   P P  +PV        P     P P 
Sbjct: 2908 LEPQLIPGPQPL---------------GPQPVHRPNPLLSPVEKRRRGRPPKARDLPIPG 2952

Query: 214  PAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLIS 273
                A          N   R Q P      + +       TA  +     +   + P   
Sbjct: 2953 TISSAG-------DGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSP--- 3002

Query: 274  DFFAKRKRSAPEKSSGDVPAPCPSPSAAP 302
                KRKR  P K+      P P PS  P
Sbjct: 3003 ---PKRKRGRPPKN-----PPSPRPSQLP 3023



 Score = 32.7 bits (73), Expect = 0.43
 Identities = 54/257 (21%), Positives = 84/257 (32%), Gaps = 50/257 (19%)

Query: 105  APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVP--VLAPAPAPAP 162
            AP P+ +      P  P    +          P    P PA TPPP    ++ P+     
Sbjct: 2470 APNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLL 2529

Query: 163  APVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPD----- 217
             P + P++A V    L   P          +P +    + A +   + +  P  D     
Sbjct: 2530 GPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVA 2589

Query: 218  ---------------AAPQESAEQGANQGQRGQE-------------------PLADQLH 243
                           +AP  + E G+    + QE                   PL     
Sbjct: 2590 VEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSES 2649

Query: 244  SGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKS----SGDVPAPCPSPS 299
            +G+   P+A +           + S  L     AK   S+PEK     + +V AP  S S
Sbjct: 2650 NGLELPPSAASDEPLQEPLEADRTSEELTE---AKTPTSSPEKPQELVTAEVAAPSTSSS 2706

Query: 300  A--APGVGSVEQTPRKR 314
            A  +P   S  + PR+R
Sbjct: 2707 ATSSPEGPSPARPPRRR 2723



 Score = 32.0 bits (71), Expect = 0.74
 Identities = 25/89 (28%), Positives = 30/89 (33%), Gaps = 11/89 (12%)

Query: 143  APASTPPPVP---------VLAPAPAPAPAPVAAP--VAAPVAVAVLAPAPAPAPAPAPA 191
            A A  PPP P         +L P P      V       AP+    + P P P  +  P 
Sbjct: 978  ATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPT 1037

Query: 192  PAPVAAPAPAPAPAPAPAPAPAPAPDAAP 220
            P PV    PA     A    P   P + P
Sbjct: 1038 PGPVPQVLPASLMVSASPAGPPLIPASRP 1066


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 72.0 bits (175), Expect = 6e-13
 Identities = 52/132 (39%), Positives = 61/132 (46%), Gaps = 16/132 (12%)

Query: 108  PVAVAVAV-SPPLEPAAESLDG--------LEEAPEQLPS-VPVPAPASTPPPVPVLAPA 157
            P+A A AV  PP  P   S +         LEE P   P   P P P   PPP P   P 
Sbjct: 1423 PLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPP---PQ 1479

Query: 158  PA-PAPAPVAAPVAAPVAVAVLAPAPAPA-PAPAPAPAPVAAPAPAPAPAP-APAPAPAP 214
            PA P+P P+ AP  +      L P P PA P+P P P P AAP  AP   P AP+P    
Sbjct: 1480 PALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPE 1539

Query: 215  APDAAPQESAEQ 226
             PD  P   A++
Sbjct: 1540 LPDTRPLHLAKK 1551



 Score = 71.6 bits (174), Expect = 8e-13
 Identities = 50/124 (40%), Positives = 57/124 (45%), Gaps = 11/124 (8%)

Query: 106  PRPVAVAVAVSPPLE--PAAESLDGLEEAP--EQLPSVPVPAPASTPPPVPVLAPAPAPA 161
            P   A AV   PPL   P+A S +G  E P  E+ P  P P PA TP P P     P P 
Sbjct: 1423 PLAPAAAVPGPPPLPGLPSANS-NGTPEPPLLEEKPP-PTPPPAPTPQPQP-----PPPP 1475

Query: 162  PAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQ 221
            P P  A  + P  VA    +P P P P P P  + +P P P PA AP  AP   P A   
Sbjct: 1476 PPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSP 1535

Query: 222  ESAE 225
            E  E
Sbjct: 1536 EDPE 1539



 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 45/113 (39%), Positives = 51/113 (45%), Gaps = 13/113 (11%)

Query: 117  PPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLA----PAPAPAPAPVAAPVAAP 172
            PPL PAA         P  LP +P      TP P P+L     P P PAP P   P   P
Sbjct: 1422 PPLAPAAAV-----PGPPPLPGLPSANSNGTPEP-PLLEEKPPPTPPPAPTPQPQPPPPP 1475

Query: 173  VAVAVLAPAPAPAPAPAPA---PAPVAAPAPAPAPAPAPAPAPAPAPDAAPQE 222
                   P+P P  AP P+   P P+  P P   P+P P P PA AP AAP E
Sbjct: 1476 PPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPE 1528



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 38/105 (36%), Positives = 46/105 (43%), Gaps = 14/105 (13%)

Query: 127  DGLEEAPEQLPSVPVPAPASTPPPV-PVLAPAPA-PAPAPVAAPVAA--------PVAVA 176
            + +  A   L   P+  P  T  P  P LAPA A P P P+    +A        P+   
Sbjct: 1396 ESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEE 1455

Query: 177  VLAPAPAPAPAPAPAPAPVAAPAPAPAPA-PAPAPAPAPAPDAAP 220
               P P PAP P P P P   P P P PA P+P P  AP P + P
Sbjct: 1456 KPPPTPPPAPTPQPQPPP---PPPPPQPALPSPPPLVAPTPSSPP 1497



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 25/80 (31%), Positives = 31/80 (38%), Gaps = 6/80 (7%)

Query: 151  VPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPA------PVAAPAPAPAP 204
            +  L   P   P   + P   P+A A   P P P P    A +      P+    P P P
Sbjct: 1402 ISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTP 1461

Query: 205  APAPAPAPAPAPDAAPQESA 224
             PAP P P P P   P + A
Sbjct: 1462 PPAPTPQPQPPPPPPPPQPA 1481



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 39/128 (30%), Positives = 50/128 (39%), Gaps = 36/128 (28%)

Query: 147 TPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAP--------APAPAPAPAPAPV--- 195
           +PPP P  A +  P P  +      P    VL P P        + AP+P+P+ + V   
Sbjct: 763 SPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVH 822

Query: 196 --------AAPAPAPAPAPAPAPAP---------------APAPDAAPQESAE-QGANQG 231
                    AP P P P P P P P               AP+P   P+ES +  GA Q 
Sbjct: 823 LLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQE 882

Query: 232 QRGQ-EPL 238
             G  EPL
Sbjct: 883 LLGALEPL 890



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 33/96 (34%), Positives = 38/96 (39%), Gaps = 16/96 (16%)

Query: 137  PSVPVPAPASTP--PPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAP 194
            P +  P   STP  PP+   A  P P P P       P A +   P P   P     P P
Sbjct: 1408 PPLAGPKDTSTPDGPPLAPAAAVPGPPPLP-----GLPSANSNGTPEP---PLLEEKPPP 1459

Query: 195  VAAPAPAPAPAPAPAP------APAPAPDAAPQESA 224
               PAP P P P P P       P+P P  AP  S+
Sbjct: 1460 TPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSS 1495



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 6/91 (6%)

Query: 129 LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAP 188
           L+++P   P  P  A ++ P P  +L  A  P    V  P    +  +VL+ AP+P+P+ 
Sbjct: 760 LQKSP---PPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSA 816

Query: 189 APAPAPVAAPAP---APAPAPAPAPAPAPAP 216
           +     +  PA    AP P P P P P P P
Sbjct: 817 SKVGVHLLEPATRDGAPQPPPPPPPPPPPMP 847



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 33/95 (34%), Positives = 39/95 (41%), Gaps = 14/95 (14%)

Query: 105  APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPA-PAPA 163
            AP P        PP +PA  S           P +  P P+S PPP     P PA P+P 
Sbjct: 1464 APTPQPQPPPPPPPPQPALPSP----------PPLVAPTPSSPPPPPLPPPPPPAMPSPP 1513

Query: 164  PVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAP 198
            P   P AAP+A     PA   AP+P     P   P
Sbjct: 1514 PPPPPAAAPLAAPPEEPA---APSPEDPELPDTRP 1545



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 53/201 (26%), Positives = 65/201 (32%), Gaps = 38/201 (18%)

Query: 106 PRPVAVAVAVS-PPLEPAAESL----DGLEEAPEQLPSVPV--------------PA--- 143
           P PV  ++++  PP  P A  L    D L   P Q P+VP               PA   
Sbjct: 161 PFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLG 220

Query: 144 PASTPPPVPVLAPAPAPAP---------------APVAAPVAAPVAVAVLAPAPAPAPAP 188
           PA TPP  P   P P P P               A  AA  ++P        AP P P  
Sbjct: 221 PAQTPPYRPG-PPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPE 279

Query: 189 APAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISG 248
              P           PA A  P P P   A     +  G+      +  LA     G   
Sbjct: 280 RALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEP 339

Query: 249 RPAAGTAAASANGAAIKKLSG 269
            P AG  + +    A    SG
Sbjct: 340 SPGAGEPSKAGPSGATAGASG 360



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 41/170 (24%), Positives = 56/170 (32%), Gaps = 15/170 (8%)

Query: 149  PPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAP 208
            PPVPV     A  P       A P        APAP P P       +   P   P  A 
Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPP------PKAPAPPPKPETPEKTTSEKPPEQTPETAM 1723

Query: 209  APAPAP-APDAAPQESAEQGANQGQRGQEPL-ADQLHSGISGRPAAGTAAASANGAAIKK 266
               PAP  P        E+   +  RG+ PL  ++  SG   RP    A      + + K
Sbjct: 1724 PEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPK 1783

Query: 267  LSGPLISDFFAKRKRSAPEK-------SSGDVPAPCPSPSAAPGVGSVEQ 309
                 +      +KR    K       + G  P       ++PG  S ++
Sbjct: 1784 ARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSEDE 1833



 Score = 37.0 bits (84), Expect = 0.023
 Identities = 32/94 (34%), Positives = 36/94 (38%), Gaps = 32/94 (34%)

Query: 103  LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAP 162
            L+AP P       SPP              P  LP  P PA  S PPP       P PA 
Sbjct: 1488 LVAPTP------SSPP--------------PPPLPPPPPPAMPSPPPP-------PPPAA 1520

Query: 163  APVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVA 196
            AP+AAP   P      AP+P     P   P  +A
Sbjct: 1521 APLAAPPEEPA-----APSPEDPELPDTRPLHLA 1549



 Score = 36.2 bits (82), Expect = 0.039
 Identities = 41/131 (31%), Positives = 52/131 (39%), Gaps = 17/131 (12%)

Query: 108 PVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPA--------PA 159
           P  ++ A SP    +   +  LE A       P P P   PPP+P+   A        PA
Sbjct: 803 PSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPA 862

Query: 160 PAPAPVAAP---VAAPVAVAVLAPAPAPAPAPAPAPAPVAAP-APAPAPAPA---PAPAP 212
            AP+P   P   +  P A+  L  A  P P PAP    V  P +    PA A   P+P  
Sbjct: 863 -APSPRLRPEESLDPPGAMQELLGALEPLP-PAPGDTGVGPPNSEGKDPAGAYRSPSPQG 920

Query: 213 APAPDAAPQES 223
             AP   P  S
Sbjct: 921 TKAPRFVPLTS 931



 Score = 32.7 bits (73), Expect = 0.43
 Identities = 23/81 (28%), Positives = 30/81 (37%), Gaps = 2/81 (2%)

Query: 143  APASTPPPVPVLAPAP--APAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAP 200
            A A  PP  P   P     P  A  A P    + +    P   P+   A     + +   
Sbjct: 976  AGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPH 1035

Query: 201  APAPAPAPAPAPAPAPDAAPQ 221
              AP P P P P PAP + P+
Sbjct: 1036 QAAPPPPPPPPPPPAPASEPK 1056



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 29/101 (28%), Positives = 36/101 (35%), Gaps = 20/101 (19%)

Query: 159 APAPAPVAAPVAAPVAVAVLAPAPAP-APAPAPAPAPVAAPAP-APAPAPAP-------- 208
           +P P P  A    P    +L  A  P  P   P P P   P+  + AP+P+P        
Sbjct: 763 SPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVH 822

Query: 209 ---------APAPAPAPDAAPQESAEQ-GANQGQRGQEPLA 239
                    AP P P P   P     Q  A+    G EP A
Sbjct: 823 LLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAA 863



 Score = 29.3 bits (64), Expect = 4.8
 Identities = 32/107 (29%), Positives = 39/107 (36%), Gaps = 23/107 (21%)

Query: 146 STPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAP-----------------APAP 188
           S P PVP       P  +P A  + +P  V  L P+ AP                  PA 
Sbjct: 159 SRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAG 218

Query: 189 -APAPAPVAAPAPAPAPAPAPAPAPAP----APDAAPQESAEQGANQ 230
             PA  P   P P P P P P   P      A  +A   +AEQ + Q
Sbjct: 219 LGPAQTPPYRPGP-PDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQ 264


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 71.6 bits (174), Expect = 8e-13
 Identities = 75/215 (34%), Positives = 86/215 (40%), Gaps = 29/215 (13%)

Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVP----APASTPPPVPVLAPAPAP 160
           AP   A   A  PP  PA  +  G      Q P  P P     PA   PP   L P P  
Sbjct: 77  APAEGAPGAAPEPP--PAGRARPG--GGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEG 132

Query: 161 APAPVAAPVAAPVAVAVLAPAPAPA-PAPAPAPAPVAAPA-PAPAPAPAPAPAPAPAPDA 218
           + A   APV A  AVA   P PAPA PA    PA +AA A P P P P P P P P   A
Sbjct: 133 S-AGSCAPVPAAAAVAA-GPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPA 190

Query: 219 APQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANG-AAIKKLSGPLISDFFA 277
            P      GA Q   G   L +  H+      AA   +   NG AA+  L  P       
Sbjct: 191 GP------GAAQTLNGSAALLNSHHA------AAPAVSLVNNGPAALLPLPKPAAPGTVI 238

Query: 278 KRKRSAPEKSSGDVPAP-CPSPSAAPGVGSVEQTP 311
              ++ P   +   PAP  PSP AAP   +    P
Sbjct: 239 ---QTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAP 270



 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 63/201 (31%), Positives = 84/201 (41%), Gaps = 35/201 (17%)

Query: 122 AAESLDGLEEAPEQLPSVPVPAPAS------TPPPVPVLAPAPAPAPAPVAAPVAAPVAV 175
           AA ++  +   P  L  +P+P PA+      TPP V   AP    AP+P AAP  A    
Sbjct: 211 AAPAVSLVNNGPAAL--LPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPA---- 264

Query: 176 AVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQ 235
              APA AP P P PAPA +A P   PA  P  APA        P  +A+ G + G    
Sbjct: 265 ---APAAAP-PPPPPAPATLARPPGHPAGPPTAAPA------VPPPAAAQNGGSAGAAPA 314

Query: 236 EPLADQLHSGISGRPAAGTAAA-------SANGAAIKKLSGPLISDFFAKRKRSAPEK-- 286
              A    +G+SG+P  G AAA       + +   + + + P      A    S      
Sbjct: 315 PAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMV 374

Query: 287 ----SSGDVPAPCPSPSAAPG 303
                 G +P+P   P  APG
Sbjct: 375 IGPTMQGALPSPAAVPPPAPG 395



 Score = 32.0 bits (71), Expect = 0.74
 Identities = 30/116 (25%), Positives = 43/116 (37%), Gaps = 2/116 (1%)

Query: 106 PRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPV 165
           P P A A A +P ++ A      ++ AP    ++    PAST   + +        P+P 
Sbjct: 329 PGPGAAAAAPAPGVK-AESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPA 387

Query: 166 AAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAP-APAPDAAP 220
           A P  AP     L    A A   + +  P A  +   A       AP  P P   P
Sbjct: 388 AVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNP 443


>gi|68563515 keratinocyte proline-rich protein [Homo sapiens]
          Length = 579

 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 43/126 (34%), Positives = 51/126 (40%), Gaps = 14/126 (11%)

Query: 106 PRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPV 165
           PRP+    +  PP       LD   E+P Q    P P P   P P   L P P P P  +
Sbjct: 376 PRPLP---SFCPP-----RRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQL 427

Query: 166 AAPVAAPVAVAVLAPAPAPAPAPAPA------PAPVAAPAPAPAPAPAPAPAPAPAPDAA 219
           + P   P  +  L P P P P P P       P P   P   P P P P P P PAP  +
Sbjct: 428 SEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPS 487

Query: 220 PQESAE 225
           P+   E
Sbjct: 488 PEPCRE 493



 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 39/109 (35%), Positives = 45/109 (41%), Gaps = 9/109 (8%)

Query: 114 AVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPV 173
           A  P L P  E    LE  P  LP   +  P   P P+P L P P P P P       P 
Sbjct: 403 APRPRLRP--EPCISLEPRPRPLPR-QLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPE 459

Query: 174 AVAVLAPAPAPAPAPAPAPAPVAAPAPAPAP------APAPAPAPAPAP 216
               L P   P P P P P P+ AP P+P P      +P+P   P P P
Sbjct: 460 PRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVP 508



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 47/160 (29%), Positives = 60/160 (37%), Gaps = 18/160 (11%)

Query: 104 LAPRPVAVAVAVSPP-LEPAAESLDGLEEAPEQLP-------SVPVPAPASTPPPVPVLA 155
           L PRP  +   +S P L P  E L  L   P  +P        +P P P   P   P   
Sbjct: 416 LEPRPRPLPRQLSEPCLYP--EPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPC 473

Query: 156 PAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 215
           P P P P P   P   P      +P+P   P P P P  +     +P      AP   P+
Sbjct: 474 PRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPS 533

Query: 216 PDAAPQESAEQGANQG-----QRGQEPLADQ--LHSGISG 248
                QES   G   G     +RGQ+   DQ    +G+ G
Sbjct: 534 SYNQGQESG-AGCGPGDVFPERRGQDGHGDQGNAFAGVKG 572



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 27/84 (32%), Positives = 30/84 (35%), Gaps = 8/84 (9%)

Query: 145 ASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAP 204
           AS P   P + P P P+  P       P +     P PAP P   P P     P P P P
Sbjct: 365 ASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLP 424

Query: 205 A--------PAPAPAPAPAPDAAP 220
                    P P PA  P P   P
Sbjct: 425 RQLSEPCLYPEPLPALRPTPRPVP 448


>gi|153791535 general control of amino acid synthesis 5-like 2 [Homo
           sapiens]
          Length = 837

 Score = 70.1 bits (170), Expect = 2e-12
 Identities = 41/97 (42%), Positives = 51/97 (52%), Gaps = 4/97 (4%)

Query: 160 PAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAA 219
           P+ AP  AP A P  +   APAP P PAP+PA AP+  P PAPAPAPA APA +      
Sbjct: 4   PSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGTGGP 63

Query: 220 PQES--AEQGANQGQRG--QEPLADQLHSGISGRPAA 252
              S  A  G +  + G  Q+  A Q  + + G P A
Sbjct: 64  GVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRA 100



 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 45/107 (42%), Positives = 50/107 (46%), Gaps = 15/107 (14%)

Query: 156 PAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 215
           P+ AP PAP A P           P  +PAPAP P PAP  +PA AP P P PAPAPAPA
Sbjct: 4   PSQAPTPAPAAQP----------RPLQSPAPAPTPTPAP--SPASAPIPTPTPAPAPAPA 51

Query: 216 PDAAPQESAEQGA-NQGQRGQEPLADQLHSGISGRPAAGTAAASANG 261
             AAP  S   G    G  G     D    G+S +  A    A   G
Sbjct: 52  --AAPAGSTGTGGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRG 96



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 38/91 (41%), Positives = 47/91 (51%), Gaps = 9/91 (9%)

Query: 140 PVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPA 199
           P PAPA+ P P+   +PAPAP P P  +P +AP+      P P PAPAPAPA AP A   
Sbjct: 8   PTPAPAAQPRPLQ--SPAPAPTPTPAPSPASAPI------PTPTPAPAPAPAAAP-AGST 58

Query: 200 PAPAPAPAPAPAPAPAPDAAPQESAEQGANQ 230
               P      A +    A P  S +Q A+Q
Sbjct: 59  GTGGPGVGSGGAGSGGDPARPGLSQQQRASQ 89



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 17/49 (34%), Positives = 20/49 (40%), Gaps = 7/49 (14%)

Query: 116 SPPLEPAAESLDGLEEAPEQLP-------SVPVPAPASTPPPVPVLAPA 157
           +P   PAA+       AP   P       S P+P P   P P P  APA
Sbjct: 7   APTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPA 55



 Score = 28.5 bits (62), Expect = 8.2
 Identities = 14/41 (34%), Positives = 18/41 (43%)

Query: 270 PLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQT 310
           PL S   A     AP  +S  +P P P+P+ AP       T
Sbjct: 18  PLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGST 58


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 51/196 (26%), Positives = 76/196 (38%), Gaps = 14/196 (7%)

Query: 108  PVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAP-APAPAPAPVA 166
            P   +    PP  P +     +++   Q P  P P    + P  PV A  AP   PA  A
Sbjct: 841  PKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKA 900

Query: 167  APVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQ 226
             P   P ++ V +P   P P  +    P   P+P PAP P P P  +P PD +     + 
Sbjct: 901  KPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKT 960

Query: 227  GANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGP----LISDFFAKRKRS 282
                   G++P            P   ++  S++GA   +   P    L+S F    +  
Sbjct: 961  SKTSSPGGKKP---------PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESG 1011

Query: 283  APEKSSGDVPAPCPSP 298
            +P K +   PA  P P
Sbjct: 1012 SPSKETLPPPAAPPKP 1027



 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 40/129 (31%), Positives = 51/129 (39%), Gaps = 13/129 (10%)

Query: 106 PRPVAVAVAVSPPLEPAAESLDGLEEAP-----EQLPSVPVPAPASTPPPVPVLAPAPAP 160
           P P +    + P   P A SL      P      Q+  +   AP + PPP P+ AP P  
Sbjct: 719 PTPGSAMAQLKPA--PCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQ 776

Query: 161 APAPVAAPVAAPVAVAVLAPA------PAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAP 214
           AP      + AP +   +AP       P P P   PA    A PA    P+P   P P P
Sbjct: 777 APPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVP 836

Query: 215 APDAAPQES 223
            P    Q+S
Sbjct: 837 PPTLPKQQS 845



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 53/192 (27%), Positives = 66/192 (34%), Gaps = 11/192 (5%)

Query: 111 VAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVA 170
           VA    PP  P    L    +AP + P V +PAP ST    PV+  A  P P P   P  
Sbjct: 758 VAPPTPPPPPPIPAPLP--PQAPPK-PLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAK 814

Query: 171 APVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQ 230
              A       P+P   P P P P      +    P P+P  +P P    Q ++      
Sbjct: 815 KQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPL-SPVPSVVKQIAS------ 867

Query: 231 GQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGD 290
            Q    P    + S       A  A  S      K    P      +      P +SS  
Sbjct: 868 -QFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLV 926

Query: 291 VPAPCPSPSAAP 302
            P P PSP  AP
Sbjct: 927 FPPPPPSPVPAP 938



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 40/136 (29%), Positives = 49/136 (36%), Gaps = 28/136 (20%)

Query: 117 PPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAV- 175
           PPL P  + +     +    P  P P P   PPP P   P P P+ +  +A  AAP+ V 
Sbjct: 607 PPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVK 666

Query: 176 ---------------AVLAPAPAPA-------PAPAPAPAPVAAPAPAPAPAPAPAPA-- 211
                          A+  P   P        P     P  V  P P P P P P  A  
Sbjct: 667 YSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMA 726

Query: 212 ---PAPAPDAAPQESA 224
              PAP   + PQ SA
Sbjct: 727 QLKPAPCAPSLPQFSA 742



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 34/112 (30%), Positives = 41/112 (36%), Gaps = 9/112 (8%)

Query: 117 PPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVP-----VLAPAPAPAPAPVAAPVAA 171
           PP  P  +S     +       V  P P   PPP P      L PAP     P  +    
Sbjct: 686 PPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPP 745

Query: 172 PVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAP---APAPAPAPDAAP 220
           P+ +  +      AP   P P P+ AP P  AP P P    PAP      AP
Sbjct: 746 PLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAP-PKPLVTIPAPTSTKTVAP 796



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 37/127 (29%), Positives = 47/127 (37%), Gaps = 25/127 (19%)

Query: 101 RLLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPP---------V 151
           ++L+ P  V       PP      ++  L+ AP   PS+P     S PPP         +
Sbjct: 700 QILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAP-CAPSLP---QFSAPPPPLKIHQVQHI 755

Query: 152 PVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPA---PAPAPAPVAAPAPAPAPAPAP 208
             +AP   P P P+ AP         L P   P P    PAP      AP    A  P P
Sbjct: 756 TQVAPPTPPPPPPIPAP---------LPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTP 806

Query: 209 APAPAPA 215
            P   PA
Sbjct: 807 TPPVPPA 813



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 37/139 (26%), Positives = 52/139 (37%), Gaps = 16/139 (11%)

Query: 175 VAVLAPAPA-PAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQR 233
           V  L+P P    P  A  P+P   P P P P P P P P P P    Q +   G+     
Sbjct: 606 VPPLSPQPKIVTPYTASQPSP-PLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMF 664

Query: 234 GQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDV-P 292
            +     +L +           A+  +GA  K  + P++     K +   P   +G V P
Sbjct: 665 VKYSTITRLQN-----------ASQHSGALFKPPTPPVMQSQSVKPQILVP--PNGVVPP 711

Query: 293 APCPSPSAAPGVGSVEQTP 311
            P P P   PG    +  P
Sbjct: 712 PPPPPPPPTPGSAMAQLKP 730



 Score = 36.2 bits (82), Expect = 0.039
 Identities = 21/65 (32%), Positives = 28/65 (43%), Gaps = 3/65 (4%)

Query: 150 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 209
           P   L P  +P P  V    A+  +  +  P P P P P P P P   P P P+ +   A
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPP---PPPLPSQSAPSA 657

Query: 210 PAPAP 214
            + AP
Sbjct: 658 GSAAP 662



 Score = 35.0 bits (79), Expect = 0.087
 Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 7/78 (8%)

Query: 130 EEAPEQLPSVPVPAPASTPPPVP---VLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAP 186
           E +  ++ S+  P  +  PP  P   ++ P  A  P+P   P   P       P P P P
Sbjct: 589 ESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPP----PPPPPPPP 644

Query: 187 APAPAPAPVAAPAPAPAP 204
            P P P+  A  A + AP
Sbjct: 645 PPPPLPSQSAPSAGSAAP 662



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 27/104 (25%), Positives = 39/104 (37%), Gaps = 6/104 (5%)

Query: 102  LLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVP-----VLAP 156
            L+  P P +   A  PP  P A        +P +  S         PPP P     + + 
Sbjct: 925  LVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSS 984

Query: 157  APAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAP 200
            + A  P P    V + V+     PA + +P+    P P A P P
Sbjct: 985  SGAEHPEPKRPSVDSLVS-KFTPPAESGSPSKETLPPPAAPPKP 1027



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 27/107 (25%), Positives = 39/107 (36%), Gaps = 6/107 (5%)

Query: 116  SPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPP-----PVPVLAPAPAPAPAPVAAPVA 170
            +P    + +S  G E    + PSV       TPP     P     P PA  P P    ++
Sbjct: 974  TPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLS 1033

Query: 171  APVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPD 217
                  VL      A AP  +     +    P+P P+ +  P P P+
Sbjct: 1034 GVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSP-PSDSDFPPPPPE 1079


>gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog A
           isoform 2 [Homo sapiens]
          Length = 548

 Score = 68.2 bits (165), Expect = 9e-12
 Identities = 65/213 (30%), Positives = 81/213 (38%), Gaps = 39/213 (18%)

Query: 129 LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVA---------------------- 166
           ++++P   P+ P P P     P    A  P PAP P                        
Sbjct: 310 MKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQ 369

Query: 167 ---APVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA---PAPAPDAAP 220
              A   AP    VL  APAPAPAPA   A   APAP P  AP P  A   PAP P  A 
Sbjct: 370 ISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAG 429

Query: 221 QESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSG---PLISDFFA 277
           + +  +   Q Q   E L   L  G S  PA  T  AS + +  ++L     P+      
Sbjct: 430 EGTLSEALLQLQFDDEDLGALL--GNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTE 487

Query: 278 KRKRSAPEKSSGDV------PAPCPSPSAAPGV 304
                 PE  +  V      P P P+P  APG+
Sbjct: 488 PMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGL 520



 Score = 29.3 bits (64), Expect = 4.8
 Identities = 19/71 (26%), Positives = 31/71 (43%), Gaps = 2/71 (2%)

Query: 82  VDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPV 141
           ++ D  P     + Q+ +   L AP P  V +  +P   PA   +  L +AP  +P +  
Sbjct: 355 INYDEFPTMVFPSGQISQASAL-APAPPQV-LPQAPAPAPAPAMVSALAQAPAPVPVLAP 412

Query: 142 PAPASTPPPVP 152
             P +  PP P
Sbjct: 413 GPPQAVAPPAP 423


>gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog A
           isoform 1 [Homo sapiens]
          Length = 551

 Score = 68.2 bits (165), Expect = 9e-12
 Identities = 65/213 (30%), Positives = 81/213 (38%), Gaps = 39/213 (18%)

Query: 129 LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVA---------------------- 166
           ++++P   P+ P P P     P    A  P PAP P                        
Sbjct: 313 MKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQ 372

Query: 167 ---APVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA---PAPAPDAAP 220
              A   AP    VL  APAPAPAPA   A   APAP P  AP P  A   PAP P  A 
Sbjct: 373 ISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAG 432

Query: 221 QESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSG---PLISDFFA 277
           + +  +   Q Q   E L   L  G S  PA  T  AS + +  ++L     P+      
Sbjct: 433 EGTLSEALLQLQFDDEDLGALL--GNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTE 490

Query: 278 KRKRSAPEKSSGDV------PAPCPSPSAAPGV 304
                 PE  +  V      P P P+P  APG+
Sbjct: 491 PMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGL 523



 Score = 29.3 bits (64), Expect = 4.8
 Identities = 19/71 (26%), Positives = 31/71 (43%), Gaps = 2/71 (2%)

Query: 82  VDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPV 141
           ++ D  P     + Q+ +   L AP P  V +  +P   PA   +  L +AP  +P +  
Sbjct: 358 INYDEFPTMVFPSGQISQASAL-APAPPQV-LPQAPAPAPAPAMVSALAQAPAPVPVLAP 415

Query: 142 PAPASTPPPVP 152
             P +  PP P
Sbjct: 416 GPPQAVAPPAP 426


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 68.2 bits (165), Expect = 9e-12
 Identities = 67/235 (28%), Positives = 81/235 (34%), Gaps = 38/235 (16%)

Query: 105  APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLP-------SVPVPAPASTPPPVPVLAPA 157
            AP P A A   SP   PA  S  G    P   P       + P P  A TPP V   +P 
Sbjct: 962  APTPPA-ATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK 1020

Query: 158  PAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAP-----------AP 206
             +PA  P     + P A    +P  +PA  P P  AP    A  P+P           AP
Sbjct: 1021 GSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP 1080

Query: 207  APAPAPAPAPDAAPQESAEQGANQGQRGQEP-----LADQLHSGISGRPAA-------GT 254
             P  A  P+P   P   + +GA        P     LA   H G    PAA       G 
Sbjct: 1081 TPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL 1140

Query: 255  AAASANGAAIKKLSGPLI--SDFFAKRKRSAPEKSSGDVPAP-----CPSPSAAP 302
            A     GA     + P            + AP   +   P+P      PSP  AP
Sbjct: 1141 ATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 66/209 (31%), Positives = 81/209 (38%), Gaps = 42/209 (20%)

Query: 106  PRPVAVAVAVSP---PLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPA- 161
            P P  +  + SP   P  PAA        +P+  P+ P P  A TPP     +P   PA 
Sbjct: 925  PAPKGIPASPSPKGAPTPPAATP-----PSPKGGPATPSPKWAPTPPAATPPSPKGGPAT 979

Query: 162  PAPVAAPVAAPVAVAVLAPAPAPA-PAPAPAPAP--VAAPAPAPAPAPAPAPAPAPAPDA 218
            P+P  AP   P A    +P   PA P+P  AP P  V  P+P  +PA  P P  A  P A
Sbjct: 980  PSPKGAPT--PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037

Query: 219  APQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAK 278
            A   S +           P A  L  G    PAA T  +   G A   L G         
Sbjct: 1038 ATPPSPK---------GSPAATPLPKGAPTTPAA-TLPSPKGGPATPSLKG--------- 1078

Query: 279  RKRSAPEKSSGDVPAP-----CPSPSAAP 302
                AP   +   P+P      PSP  AP
Sbjct: 1079 ----APTPPAATPPSPKGGPATPSPKGAP 1103



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 71/261 (27%), Positives = 91/261 (34%), Gaps = 65/261 (24%)

Query: 108  PVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAP----- 162
            P   AV    P EP A        +P++ P+ P P  A T P V   +P   PA      
Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRR 1524

Query: 163  ---APVA-----------APVAAPVAVAVLAPAPAPAPA-PAPAPAPV--------AAPA 199
               AP A           AP  A +  A+  P+P   PA P P  AP         + PA
Sbjct: 1525 DPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA 1584

Query: 200  PAP-----APAP----------APAPAPAPAPDAAPQESAEQG-ANQGQRGQEPLADQLH 243
              P     AP+P          +P+P  AP P A    S E+G A    +G         
Sbjct: 1585 VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTP 1644

Query: 244  SGISGRPAAGTAAASANGAAIKKLS-------GP--LISDFFAKRKRSAP---------- 284
            S +   P +  +     GA + + S       GP  L     A    S P          
Sbjct: 1645 SSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGP 1704

Query: 285  --EKSSGDVPAPCPSPSAAPG 303
              +KSS   P  CP PSA  G
Sbjct: 1705 QTKKSSATSPPICPDPSAKNG 1725



 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 71/242 (29%), Positives = 91/242 (37%), Gaps = 37/242 (15%)

Query: 105  APRPVAVAV-----AVSPPLEPAAESLDGLEEAPEQLPSVPVP--APA------------ 145
            AP P AV          PP E    S+  L   P++ P+ P P  APA            
Sbjct: 864  APTPSAVTPLSPKGVTLPPKETPTPSVVNLP-FPKEGPATPAPKQAPALSMTSSSPKKAR 922

Query: 146  STPPPVPVLAPAPAP--APAPVAAPVAAPV-AVAVLAPAPAPAPAPAPAPAPVAAPA-PA 201
            +TP P  + A +P+P  AP P AA   +P    A  +P  AP P  A  P+P   PA P+
Sbjct: 923  ATPAPKGIPA-SPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPS 981

Query: 202  PAPAPAPAPAPAPAPDAAPQESAEQGA------NQGQRGQEPLADQLHSGISGRPAAGTA 255
            P  AP P  A  P+P   P   + +GA              P A     G S  PAA   
Sbjct: 982  PKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPP 1041

Query: 256  AASANGAAIKKLSG----PLISDFFAKRKRSAPEKSSGDVP--APCPSPSAAPGVGSVEQ 309
            +   + AA     G    P  +    K   + P       P  A  PSP   P   S + 
Sbjct: 1042 SPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG 1101

Query: 310  TP 311
             P
Sbjct: 1102 AP 1103



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 65/232 (28%), Positives = 83/232 (35%), Gaps = 42/232 (18%)

Query: 105  APRPVAVAVAVSPPLEP---AAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPA 161
            +P+      A +PP      A  S  G    P   P  P   PA+ PP     AP P  A
Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPK---GAPTPPAA 1269

Query: 162  PAP-----VAAP--VAAPVAVAVLAPAPAPAPAPAP---APAPVAAPAPAP-----APAP 206
              P     +A P    AP    V  P+P   PA +P   AP P AA  P+P      P P
Sbjct: 1270 TPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPP 1329

Query: 207  APAPAP----APAPDAAPQESAEQGANQG--------QRGQEPLADQLHSG----ISGRP 250
              AP P     P+P   P   A   +++G        +    P A   H G        P
Sbjct: 1330 KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSP 1389

Query: 251  AAGTAAASANG----AAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSP 298
              G A  S  G     A+  LS P  +      +  A   S GD+  P  +P
Sbjct: 1390 KRGPAIPSPKGDPTSPAVIPLS-PKKAPATPVTREGAATPSKGDLTPPAVTP 1440



 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 67/273 (24%), Positives = 95/273 (34%), Gaps = 63/273 (23%)

Query: 105  APRPVAVAVA---------------------VSPPLEPA--------AESLDGLEEAP-- 133
            +P P+ V+V+                     +S P+ P         + S  G +++P  
Sbjct: 793  SPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPAT 852

Query: 134  EQLPSVPVPAPASTPPPVPVLAP--------------------------APAPAPAPVAA 167
               P+ P P  A TP  V  L+P                           PAP  AP  +
Sbjct: 853  THSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALS 912

Query: 168  PVAAPVAVAVLAPAP---APAPAPAPAPAPVAAPAPAPAPAPA-PAPAPAPAPDAAPQES 223
              ++    A   PAP     +P+P  AP P AA  P+P   PA P+P  AP P AA   S
Sbjct: 913  MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPS 972

Query: 224  AEQG-ANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRS 282
             + G A    +G             G PA  +   +    A+   S P  S       + 
Sbjct: 973  PKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS-PKGSPAATPFPKG 1031

Query: 283  APEKSSGDVPAPCPSPSAAPGVGSVEQTPRKRL 315
            A    +   P+P  SP+A P       TP   L
Sbjct: 1032 ASTPPAATPPSPKGSPAATPLPKGAPTTPAATL 1064



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 66/248 (26%), Positives = 82/248 (33%), Gaps = 53/248 (21%)

Query: 112  AVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPP---PVPVLAPAPAP-------- 160
            A   SP   PA  SL G    P   P  P   PA+  P   P+P  A  P+P        
Sbjct: 1062 ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121

Query: 161  ---APAPVAA-------------PVAAPVAVAVLAPAPA---PAPAPAPAPAPVAAPAPA 201
               AP   AA             P  AP   A   P+P      P P  AP   AA  P+
Sbjct: 1122 HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1181

Query: 202  P-----APAPAPAP----APAPAPDAAPQESAEQGANQGQRGQEP-----LADQLHSGIS 247
            P      P+P  AP    A  P+P       + +GA        P     LA     G  
Sbjct: 1182 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1241

Query: 248  GRPAA-------GTAAASANGAAIKKLSGP--LISDFFAKRKRSAPEKSSGDVPAPCPSP 298
              PAA       G A     GA     + P  L         + AP  +    P+P   P
Sbjct: 1242 TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP 1301

Query: 299  SAAPGVGS 306
            + +P  G+
Sbjct: 1302 ATSPPKGA 1309



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 37/115 (32%), Positives = 46/115 (40%), Gaps = 2/115 (1%)

Query: 116  SPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAV 175
            SP   PA  S  G   +P  +P  P  APA+         P+      P   PV+   A 
Sbjct: 1388 SPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAP 1447

Query: 176  AVLAPAPAPA-PAPAPAPAPVAAPAPAPAPAPAPAP-APAPAPDAAPQESAEQGA 228
            A  AP   PA P+    P   A   P+P   PAP   A + +P  AP   A  GA
Sbjct: 1448 ATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA 1502



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 62/236 (26%), Positives = 83/236 (35%), Gaps = 39/236 (16%)

Query: 105  APRPVAVAVAVSPPLEPAAESLDGLEEAPEQL--PSVPVPAPASTPPPVPVLAPAP--AP 160
            AP   +   A SPP    + +  G     E L  P+V  P+P   P P  V  P+P   P
Sbjct: 1570 APATPSSKEASSPPAVTPS-TYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP 1628

Query: 161  A-PAPVAAPVAAPVAVAVLAPAP-APA-----------------PA---PAPAPAPVAAP 198
            A PAP   P + PV  + L  +P +PA                 PA   P      + AP
Sbjct: 1629 ATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP 1688

Query: 199  APAPAP--------APAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRP 250
            AP   P         P    + A +P   P  SA+ G+        P         S + 
Sbjct: 1689 APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKT 1748

Query: 251  AAGTAAASANGAAI----KKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAP 302
            A G  A+ +    +     K S PL +  F K        S    P+P  S   AP
Sbjct: 1749 AKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAP 1804



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 45/184 (24%), Positives = 72/184 (39%), Gaps = 16/184 (8%)

Query: 115  VSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPV---LAPAPAPAPAPVAAPVAA 171
            ++PP   A+  L     A E++   P  A  S  P  PV   LAP+P P   P    + +
Sbjct: 1762 LAPPESKASTPLTAA--AFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPS 1819

Query: 172  PVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA-----PAPAPAPDAAPQESAEQ 226
               + + +P+   APA      P+  P P     P  +     P P  A    P  SA+Q
Sbjct: 1820 SPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQ 1879

Query: 227  GANQGQRGQ--EPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAP 284
               +  +G   E  +D+    +  + +       A  AA  ++    +S    K K+S  
Sbjct: 1880 PVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVS----KAKQSRS 1935

Query: 285  EKSS 288
            EK +
Sbjct: 1936 EKKA 1939



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 52/241 (21%), Positives = 78/241 (32%), Gaps = 37/241 (15%)

Query: 109 VAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAP-APAPAPAPVAA 167
           V++A    P  E    +L  +  A E  P  P P     P    VLAP  P   P+P   
Sbjct: 681 VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLP 740

Query: 168 PVAAPVA---------VAVLAPAPAPAPAPAPA-PAPVAAPAPAPAPAPAPAPAPAPAPD 217
           P   P            + LAP  A +P   P   +  +A A +       A +P+P   
Sbjct: 741 PAGTPPGTKKVDGISHTSALAPV-ASSPKECPTEDSGASATASSKGTLTYLADSPSPLGV 799

Query: 218 AAPQESAEQGANQGQRGQEPLADQLHSGISGRPAA--------------------GTAAA 257
           +   ++      +G  G +     L S +S   A+                         
Sbjct: 800 SVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPP 859

Query: 258 SANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAP-----CPSPSAAPGVGSVEQTPR 312
           S  GA       PL         +  P  S  ++P P      P+P  AP +     +P+
Sbjct: 860 SPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPK 919

Query: 313 K 313
           K
Sbjct: 920 K 920



 Score = 35.0 bits (79), Expect = 0.087
 Identities = 30/124 (24%), Positives = 48/124 (38%), Gaps = 10/124 (8%)

Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAP 164
           +P P    +A +P   P  +S  G        P  P   P    PP+   +PA     +P
Sbjct: 65  SPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPI---SPAALALASP 121

Query: 165 VAAPV-------AAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPD 217
           + AP        +AP+A+  LAP      +  P     + P+ A A + +     AP   
Sbjct: 122 MIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAP 181

Query: 218 AAPQ 221
           + P+
Sbjct: 182 SEPK 185



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 44/172 (25%), Positives = 63/172 (36%), Gaps = 18/172 (10%)

Query: 131 EAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAP 190
           EA E +P+     P           P    A  P+++ ++   A+    P   P  +PAP
Sbjct: 4   EATETVPATEQELPQ----------PQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAP 53

Query: 191 APAPVAAPAPAPAPAPAPAP-APAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGR 249
              P++A A   +P P+P+  A  P     PQ S+         G  P A      + G 
Sbjct: 54  QQCPLSA-ANQASPFPSPSTIASTPLEVPFPQSSSGTAL---PLGTAPEAPTFLPNLIGP 109

Query: 250 PAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAP---EKSSGDVPAPCPSP 298
           P +  A A A+      L G   S         AP   +KSS   P    SP
Sbjct: 110 PISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSP 161



 Score = 31.6 bits (70), Expect = 0.96
 Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 10/71 (14%)

Query: 102 LLLAPRPVAVA-----VAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAP 156
           LL +P  VAVA     + +S P+ P+ E    L + P ++    VP P  TP P  +++ 
Sbjct: 157 LLTSPPSVAVAESGSVITLSAPIAPS-EPKTNLNKVPSEV----VPNPKGTPSPPCIVST 211

Query: 157 APAPAPAPVAA 167
            P     P+A+
Sbjct: 212 VPYHCVTPMAS 222



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 27/105 (25%), Positives = 41/105 (39%), Gaps = 9/105 (8%)

Query: 114  AVSPPLEPAAESLDGLE---EAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVA 170
            A SPP+ P   + +G +         P +PV   +S        + +P    AP  +  +
Sbjct: 1711 ATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAS 1770

Query: 171  APVAVAV---LAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAP 212
             P+  A    + P P  A   A    PV+ P    AP+P P   P
Sbjct: 1771 TPLTAAAFEKVLPKPESASVSAAPSPPVSLPL---APSPVPTLPP 1812



 Score = 29.6 bits (65), Expect = 3.7
 Identities = 31/112 (27%), Positives = 41/112 (36%), Gaps = 5/112 (4%)

Query: 108 PVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAP-APAPAPAPVA 166
           P++ A   SP   P+  +   LE  P    S     P  T P  P   P    P  +P A
Sbjct: 57  PLSAANQASPFPSPSTIASTPLE-VPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAA 115

Query: 167 APVAAPVAVAVLAPAP---APAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 215
             +A+P+    L   P   AP    A AP  V   +  P       P+ A A
Sbjct: 116 LALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVA 167


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 47/138 (34%), Positives = 62/138 (44%), Gaps = 14/138 (10%)

Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAP-----ASTPPPVPVLAPAPA 159
           +PRP A +   SP +  AA S      +  + P+ P P P     AS  P V    PA  
Sbjct: 360 SPRPQASSY--SPAV--AASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPAST 415

Query: 160 PAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAA 219
            +P+P A     P       P+PAPA  P+PAPA   +P P   P+PAPA  P+PAP+  
Sbjct: 416 YSPSPGANYSPTPYT-----PSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYN 470

Query: 220 PQESAEQGANQGQRGQEP 237
           P  S        +    P
Sbjct: 471 PAPSVAYSGGPAEPASRP 488



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 39/97 (40%), Positives = 45/97 (46%), Gaps = 10/97 (10%)

Query: 137 PSVPVPAPASTPPPVP-------VLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPA 189
           PSV  P PAST  P P          P+PAPA  P  AP   P  V    P+PAPA  P+
Sbjct: 405 PSVYQPVPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPS 464

Query: 190 PAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQ 226
           PAP    AP+ A +  PA    PA  P     +S  Q
Sbjct: 465 PAPNYNPAPSVAYSGGPA---EPASRPPWVTDDSFSQ 498



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 56/205 (27%), Positives = 75/205 (36%), Gaps = 16/205 (7%)

Query: 117 PPLEPAAESLDGLEEAPEQLPSVPVPA-PASTPPPVPVLAPAPAPAPAPVAAPVAAPVAV 175
           P  E    S   +E AP        P  PAS  PP    +P+ A  P   AA   A  + 
Sbjct: 290 PDEEALRRSSTPIEHAPVCTSQATTPLLPASAQPPAAA-SPSAASPPLATAAAHTAIASA 348

Query: 176 AVLAPAPAPAPAPAP-----APAPVAAPAPAPAPAPAPAP-APAPAPDAAPQESAEQGAN 229
           +  APA +PA +P P     +PA  A+ APA   + +  P APAP P      S      
Sbjct: 349 STTAPASSPADSPRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVY 408

Query: 230 QGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSG 289
           Q      P+    +S   G   + T    +   A      P  +         +P  +  
Sbjct: 409 Q------PVPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYT 462

Query: 290 DVPAP--CPSPSAAPGVGSVEQTPR 312
             PAP   P+PS A   G  E   R
Sbjct: 463 PSPAPNYNPAPSVAYSGGPAEPASR 487


>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
          Length = 808

 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 70/222 (31%), Positives = 86/222 (38%), Gaps = 41/222 (18%)

Query: 111 VAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVA 170
           V VA  PP+  A         AP  L +     PA  P      APAPAPAPAP  A   
Sbjct: 34  VVVAPGPPVTTATS-------APVTLVAPGEARPAWVPGSAETSAPAPAPAPAPAPAVTG 86

Query: 171 APVAVAVLAPAP-APAP-----APAPAPAPV---------AAPAPAPAPAPA-PAPAPAP 214
           + V V  L  +P AP P       +P PA V         AA A +P    A P+PAP P
Sbjct: 87  STVVVLTLEASPEAPKPQLPSGPESPEPAAVAGVETSRALAAGADSPKTEEARPSPAPGP 146

Query: 215 -APDAAPQESAEQGANQGQRGQEPLADQ----LHSGISGRPAAGTAAASANGAAIKKLSG 269
             P   P  +  + A      + PLA +    + SG++ R A+G        AA    S 
Sbjct: 147 GTPTGTPTRTPSRTAPGALTAKPPLAPKPGTTVASGVTARSASGQVTGGHGAAAATSASA 206

Query: 270 PLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTP 311
                        APE  SG  P   PS +    V  V  TP
Sbjct: 207 -----------GQAPEDPSG--PGTGPSGTCEAPVAVVTVTP 235



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 60/174 (34%), Positives = 74/174 (42%), Gaps = 14/174 (8%)

Query: 137 PSVPVPAP-ASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPV 195
           P+ P P P  S   PV V+AP P     PV    +APV +  +AP  A  PA  P  A  
Sbjct: 18  PAAPSPPPRGSRAGPVVVVAPGP-----PVTTATSAPVTL--VAPGEA-RPAWVPGSAET 69

Query: 196 AAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGI--SGRPAAG 253
           +APAPAPAPAPAPA   +       + S E    Q   G E       +G+  S   AAG
Sbjct: 70  SAPAPAPAPAPAPAVTGSTVVVLTLEASPEAPKPQLPSGPESPEPAAVAGVETSRALAAG 129

Query: 254 TAAASANGAAIKKLSGPLISDFFAKR--KRSAPEKSSGDVP-APCPSPSAAPGV 304
             +     A      GP        R   R+AP   +   P AP P  + A GV
Sbjct: 130 ADSPKTEEARPSPAPGPGTPTGTPTRTPSRTAPGALTAKPPLAPKPGTTVASGV 183



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 47/155 (30%), Positives = 55/155 (35%), Gaps = 23/155 (14%)

Query: 105 APRPVAVA-VAVSPPLEPAAESLDGLEEAPEQLPS------VPVPAPASTPPPVPVLAPA 157
           +P P AVA V  S  L   A+S    E  P   P        P   P+ T P      P 
Sbjct: 111 SPEPAAVAGVETSRALAAGADSPKTEEARPSPAPGPGTPTGTPTRTPSRTAPGALTAKPP 170

Query: 158 PAPAPAP-VAAPVAAPVAV--------AVLAPAPAPAPAPAPAPAPVAAPA---PAPAPA 205
            AP P   VA+ V A  A         A  A + +   AP     P   P+    AP   
Sbjct: 171 LAPKPGTTVASGVTARSASGQVTGGHGAAAATSASAGQAPEDPSGPGTGPSGTCEAPVAV 230

Query: 206 PAPAPAPAPA---PDAAPQESAEQGANQGQRGQEP 237
               PAP PA    D     S   G + G RGQ P
Sbjct: 231 VTVTPAPEPAENSQDLGSTSSLGPGIS-GPRGQAP 264



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 42/154 (27%), Positives = 52/154 (33%), Gaps = 11/154 (7%)

Query: 167 APVAAPVAVAVLAPAPAPAPAPAPA-PAPVAAPAP---APAPAPAPAPAPAPAPDAAPQE 222
           AP+ AP        AP+P P  + A P  V AP P       AP    AP  A  A    
Sbjct: 6   APLVAPPRRHGAPAAPSPPPRGSRAGPVVVVAPGPPVTTATSAPVTLVAPGEARPAWVPG 65

Query: 223 SAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRS 282
           SAE  A        P      S +       T  AS      +  SGP   +  A     
Sbjct: 66  SAETSAPAPAPAPAPAPAVTGSTV----VVLTLEASPEAPKPQLPSGPESPEPAAVAGVE 121

Query: 283 APEKSSGDVPAPCPS---PSAAPGVGSVEQTPRK 313
                +    +P      PS APG G+   TP +
Sbjct: 122 TSRALAAGADSPKTEEARPSPAPGPGTPTGTPTR 155


>gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo
           sapiens]
          Length = 907

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 71/225 (31%), Positives = 84/225 (37%), Gaps = 36/225 (16%)

Query: 106 PRPVAVAVAVSPPLEPAAESLDGLEEAPE--------QLPSVPVPAP-ASTPPPVPVLAP 156
           P PVA A+      +P A S    E APE           SVPV  P AST PPVP  AP
Sbjct: 464 PTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAP 523

Query: 157 APAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAP 216
           +PAPA   VAA  AA  A    A       A     AP A           P  A AP P
Sbjct: 524 SPAPA---VAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKP 580

Query: 217 DAAPQ---------ESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAA--ASANGAAIK 265
           DAAP           S  QGA+         AD L       P+  T A  A  + + + 
Sbjct: 581 DAAPSIDLFSTDAFSSPPQGASPVPE-SSLTADLLSVDAFAAPSPATTASPAKVDSSGVI 639

Query: 266 KLSGPLISDFFAKRKRSAPEKSS------------GDVPAPCPSP 298
            L G       ++ + ++   SS            G   AP PSP
Sbjct: 640 DLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSP 684



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 56/211 (26%), Positives = 70/211 (33%), Gaps = 62/211 (29%)

Query: 137 PSVPVPAPASTP-------PPVPVLAPAPAPAPAPVAAP----------VAAPVAVAVLA 179
           P+  V +P STP       PPV + A A A  P   + P           ++  A A  A
Sbjct: 307 PATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAA 366

Query: 180 PAPAPAPAPAPA------PAPVAAPAPAPAPAPAPAP-APAPAPDAAPQESAEQGANQGQ 232
           PAP P    A A         +AA +  P+ A    P AP P P     E A   A+   
Sbjct: 367 PAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASAS--- 423

Query: 233 RGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVP 292
                             A+ T   +A  A +      L  D FA     AP  S G   
Sbjct: 424 ------------------ASTTTTVTAVTAEV-----DLFGDAFAASPGEAPAASEGAAA 460

Query: 293 APCPSPSA------------APGVGSVEQTP 311
              P+P A            AP  GS E  P
Sbjct: 461 PATPTPVAAALDACSGNDPFAPSEGSAEAAP 491



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 55/232 (23%), Positives = 73/232 (31%), Gaps = 43/232 (18%)

Query: 110 AVAVAVSPPLEPAA-----------ESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAP 158
           A A A   P  PA            +SL  L   P +       AP  TPP         
Sbjct: 361 AAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA 420

Query: 159 APAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDA 218
           + + +      A    V +   A A +P  APA +  AA    P P  A   A +     
Sbjct: 421 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF 480

Query: 219 APQESAEQGANQ----GQRGQEPLADQLHSGISGRP----------------AAGTAAAS 258
           AP E + + A +      +  E     +    S  P                AA T AA+
Sbjct: 481 APSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAAT 540

Query: 259 A------NGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGV 304
           A        +A    + P   D F     S PE       A  P P AAP +
Sbjct: 541 AAATTTTTTSAATATTAPPALDIFGDLFESTPE------VAAAPKPDAAPSI 586



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 28/100 (28%), Positives = 36/100 (36%), Gaps = 2/100 (2%)

Query: 104 LAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPA 163
           +AP   +  V  S PL+ A      +       PSV  P      PP     P     P 
Sbjct: 799 VAPATWSAGVPPSAPLQGAVPPTSSVPPVAGA-PSVGQPGAGFGMPPAGTGMPMMPQQPV 857

Query: 164 PVAAPVAAPVAVAVLAPAPAPAPAPAPA-PAPVAAPAPAP 202
             A P+  P   A   P    +P+P PA  +P   PA  P
Sbjct: 858 MFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDP 897



 Score = 32.7 bits (73), Expect = 0.43
 Identities = 56/226 (24%), Positives = 78/226 (34%), Gaps = 45/226 (19%)

Query: 105 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAP---ASTPPPVPVLAP----- 156
           AP P   A   SP    ++  +D   +A     S P PA    +S+     +LA      
Sbjct: 621 APSPATTA---SPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSF 677

Query: 157 -APAPAPA-PVAAPVAAPVAVAVLAPAPAPAPAPAPAPA----------PVAAPAPAPAP 204
            AP+P+P  P    +  P   A     P+ + + +  P+          P  APA  PAP
Sbjct: 678 MAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAP 737

Query: 205 APAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASAN---G 261
                P+PA A   A                  L   L S +     +GT     +    
Sbjct: 738 VSMVPPSPAMAASKALGSD--------------LDSSLASLVGNLGISGTTTKKGDLQWN 783

Query: 262 AAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSV 307
           A  KKL+G         + + AP   S  VP   P   A P   SV
Sbjct: 784 AGEKKLTGGA-----NWQPKVAPATWSAGVPPSAPLQGAVPPTSSV 824



 Score = 32.3 bits (72), Expect = 0.57
 Identities = 32/108 (29%), Positives = 39/108 (36%), Gaps = 11/108 (10%)

Query: 117 PPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPA------PAPVAAPVA 170
           P + PA  S      AP Q  +VP   P S+ PPV        P       PA    P+ 
Sbjct: 797 PKVAPATWSAGVPPSAPLQ-GAVP---PTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMM 852

Query: 171 APVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPA-PAPAPAPAPAPAPD 217
               V    P   P    A  P    +P+P PA  +P   PA  P  D
Sbjct: 853 PQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDPLAD 900


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.128    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,835,952
Number of Sequences: 37866
Number of extensions: 1457065
Number of successful extensions: 89213
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1618
Number of HSP's successfully gapped in prelim test: 1615
Number of HSP's that attempted gapping in prelim test: 15178
Number of HSP's gapped (non-prelim): 23900
length of query: 316
length of database: 18,247,518
effective HSP length: 102
effective length of query: 214
effective length of database: 14,385,186
effective search space: 3078429804
effective search space used: 3078429804
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press