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Search of human proteins with 45359859
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45359859 growth factor receptor-bound protein 2 isoform 2
[Homo sapiens]
(176 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45359859 growth factor receptor-bound protein 2 isoform 2 [Ho... 377 e-105
gi|4504111 growth factor receptor-bound protein 2 isoform 1 [Hom... 357 3e-99
gi|5729856 GRB2-related adaptor protein [Homo sapiens] 209 1e-54
gi|4758476 GRB2-related adaptor protein 2 [Homo sapiens] 120 8e-28
gi|193220941 hypothetical protein LOC400581 [Homo sapiens] 92 2e-19
gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo ... 86 2e-17
gi|78000167 sorbin and SH3 domain containing 1 isoform 5 [Homo s... 76 2e-14
gi|78000171 sorbin and SH3 domain containing 1 isoform 7 [Homo s... 75 2e-14
gi|78000169 sorbin and SH3 domain containing 1 isoform 6 [Homo s... 75 2e-14
gi|7661700 sorbin and SH3 domain containing 1 isoform 2 [Homo sa... 75 2e-14
gi|78000160 sorbin and SH3 domain containing 1 isoform 1 [Homo s... 75 2e-14
gi|5453754 NCK adaptor protein 1 [Homo sapiens] 75 4e-14
gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo ... 72 2e-13
gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo ... 72 2e-13
gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo ... 72 2e-13
gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo ... 72 2e-13
gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo ... 72 2e-13
gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo ... 72 2e-13
gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo s... 72 2e-13
gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo ... 72 2e-13
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 70 7e-13
gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens] 70 1e-12
gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens] 67 1e-11
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 66 2e-11
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 66 2e-11
gi|223468657 SH3-domain GRB2-like 3 [Homo sapiens] 65 3e-11
gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens] 65 4e-11
gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens] 65 4e-11
gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens] 65 4e-11
gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens] 65 4e-11
>gi|45359859 growth factor receptor-bound protein 2 isoform 2 [Homo
sapiens]
Length = 176
Score = 377 bits (968), Expect = e-105
Identities = 176/176 (100%), Positives = 176/176 (100%)
Query: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPF 60
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPF
Sbjct: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPF 60
Query: 61 GNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYV 120
GNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYV
Sbjct: 61 GNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYV 120
Query: 121 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 176
QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
Sbjct: 121 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 176
>gi|4504111 growth factor receptor-bound protein 2 isoform 1 [Homo
sapiens]
Length = 217
Score = 357 bits (916), Expect = 3e-99
Identities = 176/217 (81%), Positives = 176/217 (81%), Gaps = 41/217 (18%)
Query: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHP- 59
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHP
Sbjct: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW 60
Query: 60 ----------------------------------------FGNDVQHFKVLRDGAGKYFL 79
FGNDVQHFKVLRDGAGKYFL
Sbjct: 61 FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL 120
Query: 80 WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG 139
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
Sbjct: 121 WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG 180
Query: 140 DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 176
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
Sbjct: 181 DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 217
>gi|5729856 GRB2-related adaptor protein [Homo sapiens]
Length = 217
Score = 209 bits (532), Expect = 1e-54
Identities = 103/216 (47%), Positives = 135/216 (62%), Gaps = 43/216 (19%)
Query: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHP- 59
ME++A Y F+AT DEL+F +GD LK+LN E DQNWYKAEL G +GFIPKNYI +KPHP
Sbjct: 1 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW 60
Query: 60 ----------------------------------------FGNDVQHFKVLRDGAGKYFL 79
+G+ VQHFKVLR+ +GKYFL
Sbjct: 61 YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFL 120
Query: 80 WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQP--TYVQALFDFDPQEDGELGFR 137
W KFNSLNELVD++R+T++++ +QIFLRD E + + P + QA FDF Q+ +L FR
Sbjct: 121 WEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQDPSQLSFR 180
Query: 138 RGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVN 173
RGD I V++ DP+WW+G G+ G FPR+YV PV+
Sbjct: 181 RGDIIEVLERPDPHWWRGRSCGRVGFFPRSYVQPVH 216
>gi|4758476 GRB2-related adaptor protein 2 [Homo sapiens]
Length = 330
Score = 120 bits (300), Expect = 8e-28
Identities = 63/149 (42%), Positives = 88/149 (59%), Gaps = 42/149 (28%)
Query: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMK---- 56
MEA+AK+DF A+ +DELSF GD+LK+L+ + + W+KAEL ++G++PKN+I+++
Sbjct: 1 MEAVAKFDFTASGEDELSFHTGDVLKILSNQ--EEWFKAELGSQEGYVPKNFIDIQFPKW 58
Query: 57 ------------------------------PHPFG------NDVQHFKVLRDGAGKYFLW 80
P F +DVQHFKV+RD G YFLW
Sbjct: 59 FHEGLSRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNYFLW 118
Query: 81 VVKFNSLNELVDYHRSTSVSRNQQIFLRD 109
KF SLN+LVDY+R+ S+SR +QIFLRD
Sbjct: 119 TEKFPSLNKLVDYYRTNSISRQKQIFLRD 147
Score = 71.6 bits (174), Expect = 3e-13
Identities = 27/56 (48%), Positives = 40/56 (71%)
Query: 119 YVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNR 174
+ +AL+DF+ ED ELGF G+ + V+D+S+P+WW G H + G+FP NYV P+ R
Sbjct: 275 WARALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAPMTR 330
Score = 45.8 bits (107), Expect = 2e-05
Identities = 21/51 (41%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
Query: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYI 53
A A YDF+A DDEL F G++++VL + + +W+ L+ K G P NY+
Sbjct: 276 ARALYDFEALEDDELGFHSGEVVEVL-DSSNPSWWTGRLHNKLGLFPANYV 325
Score = 37.7 bits (86), Expect = 0.005
Identities = 16/48 (33%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 122 ALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
A FDF + EL F GD + ++ N + W+K Q G P+N++
Sbjct: 5 AKFDFTASGEDELSFHTGDVLKILSNQE-EWFKAELGSQEGYVPKNFI 51
>gi|193220941 hypothetical protein LOC400581 [Homo sapiens]
Length = 118
Score = 92.4 bits (228), Expect = 2e-19
Identities = 40/60 (66%), Positives = 49/60 (81%)
Query: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPF 60
ME++A Y F+AT DEL+F +GD LK+LN E DQNWYKAEL G +GFIPKNYI +KPHP+
Sbjct: 1 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW 60
Score = 43.9 bits (102), Expect = 7e-05
Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Query: 122 ALFDFDPQEDGELGFRRGDFIHVMD-NSDPNWWKGACHGQTGMFPRNYV 169
AL+ F E EL F +GD + +++ D NW+K G G P+NY+
Sbjct: 5 ALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYI 53
>gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo
sapiens]
Length = 665
Score = 85.9 bits (211), Expect = 2e-17
Identities = 49/174 (28%), Positives = 83/174 (47%), Gaps = 28/174 (16%)
Query: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYI-----EM 55
+EAI ++D++A DDEL+ G+I+ + +E D W++ ++NG+ G P N++ EM
Sbjct: 2 VEAIVEFDYQAQHDDELTISVGEIITNIRKE-DGGWWEGQINGRRGLFPDNFVREIKKEM 60
Query: 56 KPHPFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQ 115
K P N + +G L + + LR ++ +
Sbjct: 61 KKDPLTNKAPEKPLHEVPSGNSLL----------------------SSETILRTNKRGER 98
Query: 116 QPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
+ Q F + PQ D EL + GD I V+ + WW+G +G+TGMFP N++
Sbjct: 99 RRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFI 152
Score = 56.6 bits (135), Expect = 1e-08
Identities = 27/78 (34%), Positives = 46/78 (58%), Gaps = 9/78 (11%)
Query: 7 YDFKATADDELSFKRGDILKVLNEEC-DQNWYKAELNGKDGFIPKNYIEMKPHPFGNDVQ 65
+ ++A DDEL+ K GDI+ ++N++C D W++ ELNG+ G P N++++ P F +
Sbjct: 276 FPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPPDFEKEGN 335
Query: 66 HFK--------VLRDGAG 75
K V++ GAG
Sbjct: 336 RPKKPPPPSAPVIKQGAG 353
Score = 46.6 bits (109), Expect = 1e-05
Identities = 18/53 (33%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
Query: 119 YVQALFDFDPQEDGELGFRRGDFIHVMDNS--DPNWWKGACHGQTGMFPRNYV 169
Y + +F ++ Q D EL + GD + +++ D WW+G +G+ G+FP N+V
Sbjct: 271 YCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFV 323
Score = 45.8 bits (107), Expect = 2e-05
Identities = 18/53 (33%), Positives = 29/53 (54%)
Query: 124 FDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 176
FD+ Q D EL G+ I + D WW+G +G+ G+FP N+V + + +
Sbjct: 8 FDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFVREIKKEM 60
Score = 43.9 bits (102), Expect = 7e-05
Identities = 19/41 (46%), Positives = 28/41 (68%), Gaps = 1/41 (2%)
Query: 14 DDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE 54
DDEL K GDI++V+ E ++ W++ LNGK G P N+I+
Sbjct: 114 DDELELKVGDIIEVVGE-VEEGWWEGVLNGKTGMFPSNFIK 153
>gi|78000167 sorbin and SH3 domain containing 1 isoform 5 [Homo
sapiens]
Length = 905
Score = 75.9 bits (185), Expect = 2e-14
Identities = 54/183 (29%), Positives = 84/183 (45%), Gaps = 13/183 (7%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNG--KDGFIPKNYIEMKPHP 59
EAIAK++F E+SF++G+ + +L + D+NWY+ + G + G P Y+++ P
Sbjct: 722 EAIAKFNFNGDTQVEMSFRKGERITLLRQ-VDENWYEGRIPGTSRQGIFPITYVDVIKRP 780
Query: 60 FGNDVQHFKVL-------RDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLR-DIE 111
+ + L R L + +L + +S + QQ + D
Sbjct: 781 LVKNPVDYMDLPFSSSPSRSATASPQLSHHSLRAGPDLTESEKSYVQPQAQQRRVTPDRS 840
Query: 112 QVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACH--GQTGMFPRNYV 169
Q Q QAL+ + PQ D EL R GD + VM+ D W+ G Q G FP NYV
Sbjct: 841 QTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYV 900
Query: 170 TPV 172
P+
Sbjct: 901 KPL 903
Score = 63.9 bits (154), Expect = 7e-11
Identities = 48/174 (27%), Positives = 74/174 (42%), Gaps = 45/174 (25%)
Query: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPFGN 62
A AK+DFKA EL ++GDI+ + ++ DQNWY+ E +G+ G P+ YIE+ P
Sbjct: 649 ARAKFDFKAQTLKELPLQKGDIVYIY-KQIDQNWYEGEHHGRVGIFPRTYIELLPP--AE 705
Query: 63 DVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQA 122
Q K+ +Y + KFN
Sbjct: 706 KAQPKKLTPVQVLEYGEAIAKFN------------------------------------- 728
Query: 123 LFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHG--QTGMFPRNYVTPVNR 174
F+ E+ FR+G+ I ++ D NW++G G + G+FP YV + R
Sbjct: 729 ---FNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVIKR 779
>gi|78000171 sorbin and SH3 domain containing 1 isoform 7 [Homo
sapiens]
Length = 740
Score = 75.5 bits (184), Expect = 2e-14
Identities = 51/175 (29%), Positives = 77/175 (44%), Gaps = 17/175 (9%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNG--KDGFIPKNYIEMKPHP 59
EAIAK++F E+SF++G+ + +L + D+NWY+ + G + G P Y+++ P
Sbjct: 577 EAIAKFNFNGDTQVEMSFRKGERITLLRQ-VDENWYEGRIPGTSRQGIFPITYVDVIKRP 635
Query: 60 FGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTY 119
+ + L F+S Q+ D Q Q
Sbjct: 636 LVKNPVDYMDL------------PFSSSPSRSATASPQQPQAQQRRVTPDRSQTSQDLFS 683
Query: 120 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACH--GQTGMFPRNYVTPV 172
QAL+ + PQ D EL R GD + VM+ D W+ G Q G FP NYV P+
Sbjct: 684 YQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPL 738
Score = 50.8 bits (120), Expect = 6e-07
Identities = 20/49 (40%), Positives = 31/49 (63%)
Query: 121 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
+A FDF Q EL ++GD +++ D NW++G HG+ G+FPR Y+
Sbjct: 505 RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYI 553
>gi|78000169 sorbin and SH3 domain containing 1 isoform 6 [Homo
sapiens]
Length = 781
Score = 75.5 bits (184), Expect = 2e-14
Identities = 51/175 (29%), Positives = 77/175 (44%), Gaps = 17/175 (9%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNG--KDGFIPKNYIEMKPHP 59
EAIAK++F E+SF++G+ + +L + D+NWY+ + G + G P Y+++ P
Sbjct: 618 EAIAKFNFNGDTQVEMSFRKGERITLLRQ-VDENWYEGRIPGTSRQGIFPITYVDVIKRP 676
Query: 60 FGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTY 119
+ + L F+S Q+ D Q Q
Sbjct: 677 LVKNPVDYMDL------------PFSSSPSRSATASPQQPQAQQRRVTPDRSQTSQDLFS 724
Query: 120 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACH--GQTGMFPRNYVTPV 172
QAL+ + PQ D EL R GD + VM+ D W+ G Q G FP NYV P+
Sbjct: 725 YQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPL 779
Score = 50.8 bits (120), Expect = 6e-07
Identities = 20/49 (40%), Positives = 31/49 (63%)
Query: 121 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
+A FDF Q EL ++GD +++ D NW++G HG+ G+FPR Y+
Sbjct: 546 RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYI 594
>gi|7661700 sorbin and SH3 domain containing 1 isoform 2 [Homo
sapiens]
Length = 816
Score = 75.5 bits (184), Expect = 2e-14
Identities = 51/175 (29%), Positives = 77/175 (44%), Gaps = 17/175 (9%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNG--KDGFIPKNYIEMKPHP 59
EAIAK++F E+SF++G+ + +L + D+NWY+ + G + G P Y+++ P
Sbjct: 653 EAIAKFNFNGDTQVEMSFRKGERITLLRQ-VDENWYEGRIPGTSRQGIFPITYVDVIKRP 711
Query: 60 FGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTY 119
+ + L F+S Q+ D Q Q
Sbjct: 712 LVKNPVDYMDL------------PFSSSPSRSATASPQQPQAQQRRVTPDRSQTSQDLFS 759
Query: 120 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACH--GQTGMFPRNYVTPV 172
QAL+ + PQ D EL R GD + VM+ D W+ G Q G FP NYV P+
Sbjct: 760 YQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPL 814
Score = 50.8 bits (120), Expect = 6e-07
Identities = 20/49 (40%), Positives = 31/49 (63%)
Query: 121 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
+A FDF Q EL ++GD +++ D NW++G HG+ G+FPR Y+
Sbjct: 581 RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYI 629
>gi|78000160 sorbin and SH3 domain containing 1 isoform 1 [Homo
sapiens]
Length = 684
Score = 75.5 bits (184), Expect = 2e-14
Identities = 51/175 (29%), Positives = 77/175 (44%), Gaps = 17/175 (9%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNG--KDGFIPKNYIEMKPHP 59
EAIAK++F E+SF++G+ + +L + D+NWY+ + G + G P Y+++ P
Sbjct: 521 EAIAKFNFNGDTQVEMSFRKGERITLLRQ-VDENWYEGRIPGTSRQGIFPITYVDVIKRP 579
Query: 60 FGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTY 119
+ + L F+S Q+ D Q Q
Sbjct: 580 LVKNPVDYMDL------------PFSSSPSRSATASPQQPQAQQRRVTPDRSQTSQDLFS 627
Query: 120 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACH--GQTGMFPRNYVTPV 172
QAL+ + PQ D EL R GD + VM+ D W+ G Q G FP NYV P+
Sbjct: 628 YQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPL 682
Score = 50.8 bits (120), Expect = 6e-07
Identities = 20/49 (40%), Positives = 31/49 (63%)
Query: 121 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
+A FDF Q EL ++GD +++ D NW++G HG+ G+FPR Y+
Sbjct: 449 RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYI 497
>gi|5453754 NCK adaptor protein 1 [Homo sapiens]
Length = 377
Score = 74.7 bits (182), Expect = 4e-14
Identities = 54/179 (30%), Positives = 81/179 (45%), Gaps = 38/179 (21%)
Query: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYI-EMKPHP 59
M A K+++ A +DELS +G + V+ E+C W++ NG+ G+ P NY+ E P
Sbjct: 109 MPAYVKFNYMAEREDELSLIKGTKVIVM-EKCSDGWWRGSYNGQVGWFPSNYVTEEGDSP 167
Query: 60 FGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTY 119
G+ V SL+E + +V N Q
Sbjct: 168 LGDHV--------------------GSLSE-----KLAAVVNNLN--------TGQVLHV 194
Query: 120 VQALFDFDPQEDGELGFRRGDFIHVMD--NSDPNWWK-GACHGQTGMFPRNYVTPVNRN 175
VQAL+ F D EL F +GD + V++ +DP WWK +G G+ P+NYVT + N
Sbjct: 195 VQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYVTVMQNN 253
Score = 70.1 bits (170), Expect = 9e-13
Identities = 49/170 (28%), Positives = 86/170 (50%), Gaps = 19/170 (11%)
Query: 4 IAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELN-GKDGFIPKNYIEMKPHPFGN 62
+AK+D+ A + EL K+ + L +L++ ++W++ + K GF+P NY+E K
Sbjct: 8 VAKFDYVAQQEQELDIKKNERLWLLDDS--KSWWRVRNSMNKTGFVPSNYVERKNS--AR 63
Query: 63 DVQHFKVLRD--GAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYV 120
K L+D G GK V + S+ + + V ++++ D+ P YV
Sbjct: 64 KASIVKNLKDTLGIGK----VKRKPSVPDSASPADDSFVDPGERLY--DLNM----PAYV 113
Query: 121 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVT 170
+ F++ + + EL +G + VM+ WW+G+ +GQ G FP NYVT
Sbjct: 114 K--FNYMAEREDELSLIKGTKVIVMEKCSDGWWRGSYNGQVGWFPSNYVT 161
Score = 33.5 bits (75), Expect = 0.098
Identities = 17/54 (31%), Positives = 28/54 (51%)
Query: 120 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVN 173
V A FD+ Q++ EL ++ + + ++D+S W +TG P NYV N
Sbjct: 7 VVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKN 60
>gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo
sapiens]
Length = 492
Score = 72.4 bits (176), Expect = 2e-13
Identities = 53/172 (30%), Positives = 84/172 (48%), Gaps = 20/172 (11%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNG--KDGFIPKNYIEMKPHP 59
EAIAKY+F A + ELS ++GD + +L + DQNWY+ ++ G + G P +Y+E+
Sbjct: 334 EAIAKYNFNADTNVELSLRKGDRV-ILLKRVDQNWYEGKIPGTNRQGIFPVSYVEV---- 388
Query: 60 FGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTY 119
K GA Y + + ++ + H +S + +F + Q +P
Sbjct: 389 -------VKKNTKGAEDYPDPPIPHSYSSDRI--HSLSSNKPQRPVFTHENIQGGGEP-- 437
Query: 120 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQT--GMFPRNYV 169
QAL+++ P+ + EL R D I VM+ D W+ G G FP NYV
Sbjct: 438 FQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYV 489
Score = 55.5 bits (132), Expect = 2e-08
Identities = 27/59 (45%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHP 59
+ A A YDFKA ELSFK+GD + +L + DQNWY+ E +G+ G P +Y+E P
Sbjct: 258 LPAKAVYDFKAQTSKELSFKKGDTVYIL-RKIDQNWYEGEHHGRVGIFPISYVEKLTPP 315
Score = 53.5 bits (127), Expect = 9e-08
Identities = 20/49 (40%), Positives = 34/49 (69%)
Query: 121 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
+A++DF Q EL F++GD ++++ D NW++G HG+ G+FP +YV
Sbjct: 261 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYV 309
>gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo
sapiens]
Length = 1004
Score = 72.4 bits (176), Expect = 2e-13
Identities = 53/172 (30%), Positives = 84/172 (48%), Gaps = 20/172 (11%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNG--KDGFIPKNYIEMKPHP 59
EAIAKY+F A + ELS ++GD + +L + DQNWY+ ++ G + G P +Y+E+
Sbjct: 846 EAIAKYNFNADTNVELSLRKGDRV-ILLKRVDQNWYEGKIPGTNRQGIFPVSYVEV---- 900
Query: 60 FGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTY 119
K GA Y + + ++ + H +S + +F + Q +P
Sbjct: 901 -------VKKNTKGAEDYPDPPIPHSYSSDRI--HSLSSNKPQRPVFTHENIQGGGEP-- 949
Query: 120 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQT--GMFPRNYV 169
QAL+++ P+ + EL R D I VM+ D W+ G G FP NYV
Sbjct: 950 FQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYV 1001
Score = 55.5 bits (132), Expect = 2e-08
Identities = 27/59 (45%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHP 59
+ A A YDFKA ELSFK+GD + +L + DQNWY+ E +G+ G P +Y+E P
Sbjct: 770 LPAKAVYDFKAQTSKELSFKKGDTVYIL-RKIDQNWYEGEHHGRVGIFPISYVEKLTPP 827
Score = 53.5 bits (127), Expect = 9e-08
Identities = 20/49 (40%), Positives = 34/49 (69%)
Query: 121 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
+A++DF Q EL F++GD ++++ D NW++G HG+ G+FP +YV
Sbjct: 773 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYV 821
>gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo
sapiens]
Length = 824
Score = 72.4 bits (176), Expect = 2e-13
Identities = 53/172 (30%), Positives = 84/172 (48%), Gaps = 20/172 (11%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNG--KDGFIPKNYIEMKPHP 59
EAIAKY+F A + ELS ++GD + +L + DQNWY+ ++ G + G P +Y+E+
Sbjct: 666 EAIAKYNFNADTNVELSLRKGDRV-ILLKRVDQNWYEGKIPGTNRQGIFPVSYVEV---- 720
Query: 60 FGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTY 119
K GA Y + + ++ + H +S + +F + Q +P
Sbjct: 721 -------VKKNTKGAEDYPDPPIPHSYSSDRI--HSLSSNKPQRPVFTHENIQGGGEP-- 769
Query: 120 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQT--GMFPRNYV 169
QAL+++ P+ + EL R D I VM+ D W+ G G FP NYV
Sbjct: 770 FQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYV 821
Score = 55.5 bits (132), Expect = 2e-08
Identities = 27/59 (45%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHP 59
+ A A YDFKA ELSFK+GD + +L + DQNWY+ E +G+ G P +Y+E P
Sbjct: 590 LPAKAVYDFKAQTSKELSFKKGDTVYIL-RKIDQNWYEGEHHGRVGIFPISYVEKLTPP 647
Score = 53.5 bits (127), Expect = 9e-08
Identities = 20/49 (40%), Positives = 34/49 (69%)
Query: 121 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
+A++DF Q EL F++GD ++++ D NW++G HG+ G+FP +YV
Sbjct: 593 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYV 641
>gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo
sapiens]
Length = 661
Score = 72.4 bits (176), Expect = 2e-13
Identities = 53/172 (30%), Positives = 84/172 (48%), Gaps = 20/172 (11%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNG--KDGFIPKNYIEMKPHP 59
EAIAKY+F A + ELS ++GD + +L + DQNWY+ ++ G + G P +Y+E+
Sbjct: 503 EAIAKYNFNADTNVELSLRKGDRV-ILLKRVDQNWYEGKIPGTNRQGIFPVSYVEV---- 557
Query: 60 FGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTY 119
K GA Y + + ++ + H +S + +F + Q +P
Sbjct: 558 -------VKKNTKGAEDYPDPPIPHSYSSDRI--HSLSSNKPQRPVFTHENIQGGGEP-- 606
Query: 120 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQT--GMFPRNYV 169
QAL+++ P+ + EL R D I VM+ D W+ G G FP NYV
Sbjct: 607 FQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYV 658
Score = 55.5 bits (132), Expect = 2e-08
Identities = 27/59 (45%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHP 59
+ A A YDFKA ELSFK+GD + +L + DQNWY+ E +G+ G P +Y+E P
Sbjct: 427 LPAKAVYDFKAQTSKELSFKKGDTVYIL-RKIDQNWYEGEHHGRVGIFPISYVEKLTPP 484
Score = 53.5 bits (127), Expect = 9e-08
Identities = 20/49 (40%), Positives = 34/49 (69%)
Query: 121 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
+A++DF Q EL F++GD ++++ D NW++G HG+ G+FP +YV
Sbjct: 430 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYV 478
>gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo
sapiens]
Length = 731
Score = 72.4 bits (176), Expect = 2e-13
Identities = 53/172 (30%), Positives = 84/172 (48%), Gaps = 20/172 (11%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNG--KDGFIPKNYIEMKPHP 59
EAIAKY+F A + ELS ++GD + +L + DQNWY+ ++ G + G P +Y+E+
Sbjct: 573 EAIAKYNFNADTNVELSLRKGDRV-ILLKRVDQNWYEGKIPGTNRQGIFPVSYVEV---- 627
Query: 60 FGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTY 119
K GA Y + + ++ + H +S + +F + Q +P
Sbjct: 628 -------VKKNTKGAEDYPDPPIPHSYSSDRI--HSLSSNKPQRPVFTHENIQGGGEP-- 676
Query: 120 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQT--GMFPRNYV 169
QAL+++ P+ + EL R D I VM+ D W+ G G FP NYV
Sbjct: 677 FQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYV 728
Score = 55.5 bits (132), Expect = 2e-08
Identities = 27/59 (45%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHP 59
+ A A YDFKA ELSFK+GD + +L + DQNWY+ E +G+ G P +Y+E P
Sbjct: 497 LPAKAVYDFKAQTSKELSFKKGDTVYIL-RKIDQNWYEGEHHGRVGIFPISYVEKLTPP 554
Score = 53.5 bits (127), Expect = 9e-08
Identities = 20/49 (40%), Positives = 34/49 (69%)
Query: 121 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
+A++DF Q EL F++GD ++++ D NW++G HG+ G+FP +YV
Sbjct: 500 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYV 548
>gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo
sapiens]
Length = 644
Score = 72.4 bits (176), Expect = 2e-13
Identities = 53/172 (30%), Positives = 84/172 (48%), Gaps = 20/172 (11%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNG--KDGFIPKNYIEMKPHP 59
EAIAKY+F A + ELS ++GD + +L + DQNWY+ ++ G + G P +Y+E+
Sbjct: 486 EAIAKYNFNADTNVELSLRKGDRV-ILLKRVDQNWYEGKIPGTNRQGIFPVSYVEV---- 540
Query: 60 FGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTY 119
K GA Y + + ++ + H +S + +F + Q +P
Sbjct: 541 -------VKKNTKGAEDYPDPPIPHSYSSDRI--HSLSSNKPQRPVFTHENIQGGGEP-- 589
Query: 120 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQT--GMFPRNYV 169
QAL+++ P+ + EL R D I VM+ D W+ G G FP NYV
Sbjct: 590 FQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYV 641
Score = 55.5 bits (132), Expect = 2e-08
Identities = 27/59 (45%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHP 59
+ A A YDFKA ELSFK+GD + +L + DQNWY+ E +G+ G P +Y+E P
Sbjct: 410 LPAKAVYDFKAQTSKELSFKKGDTVYIL-RKIDQNWYEGEHHGRVGIFPISYVEKLTPP 467
Score = 53.5 bits (127), Expect = 9e-08
Identities = 20/49 (40%), Positives = 34/49 (69%)
Query: 121 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
+A++DF Q EL F++GD ++++ D NW++G HG+ G+FP +YV
Sbjct: 413 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYV 461
>gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo
sapiens]
Length = 1100
Score = 72.4 bits (176), Expect = 2e-13
Identities = 53/172 (30%), Positives = 84/172 (48%), Gaps = 20/172 (11%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNG--KDGFIPKNYIEMKPHP 59
EAIAKY+F A + ELS ++GD + +L + DQNWY+ ++ G + G P +Y+E+
Sbjct: 942 EAIAKYNFNADTNVELSLRKGDRV-ILLKRVDQNWYEGKIPGTNRQGIFPVSYVEV---- 996
Query: 60 FGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTY 119
K GA Y + + ++ + H +S + +F + Q +P
Sbjct: 997 -------VKKNTKGAEDYPDPPIPHSYSSDRI--HSLSSNKPQRPVFTHENIQGGGEP-- 1045
Query: 120 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQT--GMFPRNYV 169
QAL+++ P+ + EL R D I VM+ D W+ G G FP NYV
Sbjct: 1046 FQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYV 1097
Score = 55.5 bits (132), Expect = 2e-08
Identities = 27/59 (45%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHP 59
+ A A YDFKA ELSFK+GD + +L + DQNWY+ E +G+ G P +Y+E P
Sbjct: 866 LPAKAVYDFKAQTSKELSFKKGDTVYIL-RKIDQNWYEGEHHGRVGIFPISYVEKLTPP 923
Score = 53.5 bits (127), Expect = 9e-08
Identities = 20/49 (40%), Positives = 34/49 (69%)
Query: 121 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
+A++DF Q EL F++GD ++++ D NW++G HG+ G+FP +YV
Sbjct: 869 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYV 917
>gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo
sapiens]
Length = 666
Score = 72.4 bits (176), Expect = 2e-13
Identities = 53/172 (30%), Positives = 84/172 (48%), Gaps = 20/172 (11%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNG--KDGFIPKNYIEMKPHP 59
EAIAKY+F A + ELS ++GD + +L + DQNWY+ ++ G + G P +Y+E+
Sbjct: 508 EAIAKYNFNADTNVELSLRKGDRV-ILLKRVDQNWYEGKIPGTNRQGIFPVSYVEV---- 562
Query: 60 FGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTY 119
K GA Y + + ++ + H +S + +F + Q +P
Sbjct: 563 -------VKKNTKGAEDYPDPPIPHSYSSDRI--HSLSSNKPQRPVFTHENIQGGGEP-- 611
Query: 120 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQT--GMFPRNYV 169
QAL+++ P+ + EL R D I VM+ D W+ G G FP NYV
Sbjct: 612 FQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYV 663
Score = 55.5 bits (132), Expect = 2e-08
Identities = 27/59 (45%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHP 59
+ A A YDFKA ELSFK+GD + +L + DQNWY+ E +G+ G P +Y+E P
Sbjct: 432 LPAKAVYDFKAQTSKELSFKKGDTVYIL-RKIDQNWYEGEHHGRVGIFPISYVEKLTPP 489
Score = 53.5 bits (127), Expect = 9e-08
Identities = 20/49 (40%), Positives = 34/49 (69%)
Query: 121 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
+A++DF Q EL F++GD ++++ D NW++G HG+ G+FP +YV
Sbjct: 435 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYV 483
>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
sapiens]
Length = 756
Score = 70.5 bits (171), Expect = 7e-13
Identities = 45/170 (26%), Positives = 73/170 (42%), Gaps = 27/170 (15%)
Query: 7 YDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMK---PHPFGND 63
+ + DEL + G+I++++ +E + W+ + NG+ G P N++E+ P GN
Sbjct: 92 FSYSPEQADELKLQAGEIVEMI-KEIEDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNP 150
Query: 64 VQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQAL 123
+ G R +S D Q P + L
Sbjct: 151 --DMPSVSPGP-------------------QRPPKLSSLAYDSPPDYLQTVSHPEVYRVL 189
Query: 124 FDFDPQEDGELGFRRGDFIHVMDNS--DPNWWKGACHGQTGMFPRNYVTP 171
FD+ P+ EL RRGD + V+ + D WW+G C G+ G+FP N+V P
Sbjct: 190 FDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFVLP 239
Score = 54.3 bits (129), Expect = 5e-08
Identities = 37/169 (21%), Positives = 71/169 (42%), Gaps = 32/169 (18%)
Query: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPF 60
ME + ++A +DELS GD+++ + + W + E G+ G P+ ++ P
Sbjct: 1 MEVLVLAGYRAQKEDELSLAPGDVVRQVRWVPARGWLRGEFGGRYGLFPERLVQEIP--- 57
Query: 61 GNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYV 120
+ LR G+G+ R +R + + P+ +
Sbjct: 58 -------ETLR-GSGEA-----------------RRPRCARRRGHPAKH----PRPQRWC 88
Query: 121 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
+ F + P++ EL + G+ + ++ + WW G +GQ G FP N+V
Sbjct: 89 KVNFSYSPEQADELKLQAGEIVEMIKEIEDGWWLGKKNGQLGAFPSNFV 137
Score = 48.5 bits (114), Expect = 3e-06
Identities = 24/69 (34%), Positives = 41/69 (59%), Gaps = 2/69 (2%)
Query: 7 YDFKATADDELSFKRGDILKVLNEEC-DQNWYKAELNGKDGFIPKNYIEMKPHPFGNDVQ 65
+D++ A DEL+ +RGD++KVL++ D+ W++ E G+ G P N++ + P P V
Sbjct: 190 FDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFV-LPPPPIKKLVP 248
Query: 66 HFKVLRDGA 74
V R+ A
Sbjct: 249 RKVVSRESA 257
>gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens]
Length = 540
Score = 69.7 bits (169), Expect = 1e-12
Identities = 28/51 (54%), Positives = 38/51 (74%)
Query: 120 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVT 170
V+A++DF+ ED EL F+ G+ I V+D+SDPNWWKG H G+FP N+VT
Sbjct: 215 VRAIYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGIGLFPSNFVT 265
Score = 49.7 bits (117), Expect = 1e-06
Identities = 28/74 (37%), Positives = 40/74 (54%), Gaps = 14/74 (18%)
Query: 5 AKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYI----------- 53
A YDF+A D+EL+FK G+I+ VL ++ D NW+K E + G P N++
Sbjct: 217 AIYDFEAAEDNELTFKAGEIITVL-DDSDPNWWKGETHQGIGLFPSNFVTADLTAEPEMI 275
Query: 54 --EMKPHPFGNDVQ 65
E K F +DVQ
Sbjct: 276 KTEKKTVQFSDDVQ 289
>gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens]
Length = 525
Score = 66.6 bits (161), Expect = 1e-11
Identities = 30/57 (52%), Positives = 40/57 (70%), Gaps = 1/57 (1%)
Query: 120 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 176
V+AL+DF+ ED EL F+ G+ I V+D+SD NWWKG H G+FP N+VT N N+
Sbjct: 207 VRALYDFEAVEDNELTFKHGEIIIVLDDSDANWWKGENHRGIGLFPSNFVT-TNLNI 262
Score = 48.1 bits (113), Expect = 4e-06
Identities = 22/49 (44%), Positives = 33/49 (67%), Gaps = 1/49 (2%)
Query: 5 AKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYI 53
A YDF+A D+EL+FK G+I+ VL ++ D NW+K E + G P N++
Sbjct: 209 ALYDFEAVEDNELTFKHGEIIIVL-DDSDANWWKGENHRGIGLFPSNFV 256
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 65.9 bits (159), Expect = 2e-11
Identities = 40/169 (23%), Positives = 79/169 (46%), Gaps = 29/169 (17%)
Query: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPF 60
++A A Y ++A D+ L+F + D++ VL ++ W+ E+ G+ G+ PK+Y+++ P
Sbjct: 916 LQAQALYPWRAKKDNHLNFNKNDVITVLEQQ--DMWWFGEVQGQKGWFPKSYVKLISGPI 973
Query: 61 GNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYV 120
+D S S + +++ + V ++
Sbjct: 974 RKSTS-------------------------MDSGSSESPASLKRVASPAAKPVVSGEEFI 1008
Query: 121 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
A++ ++ E G+L F++GD I ++ D +WW G + G+FP NYV
Sbjct: 1009 -AMYTYESSEQGDLTFQQGDVI-LVTKKDGDWWTGTVGDKAGVFPSNYV 1055
Score = 64.3 bits (155), Expect = 5e-11
Identities = 44/173 (25%), Positives = 76/173 (43%), Gaps = 48/173 (27%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKD-----GFIPKNYIEMK 56
+ IA Y AT ++L+ G ++ ++ ++ W++ EL + G+ P NY+
Sbjct: 1080 QVIASYT--ATGPEQLTLAPGQLI-LIRKKNPGGWWEGELQARGKKRQIGWFPANYV--- 1133
Query: 57 PHPFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQ 116
K+L G K + +ST+++ Q+
Sbjct: 1134 -----------KLLSPGTSKI-----------TPTEPPKSTALAAVCQVI---------- 1161
Query: 117 PTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
++D+ Q D EL F +G I+V++ DP+WWKG +GQ G+FP NYV
Sbjct: 1162 -----GMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYV 1209
Score = 59.7 bits (143), Expect = 1e-09
Identities = 25/54 (46%), Positives = 38/54 (70%), Gaps = 1/54 (1%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEM 55
+ I YD+ A DDEL+F +G I+ VLN+E D +W+K E+NG+ G P NY+++
Sbjct: 1159 QVIGMYDYTAQNDDELAFNKGQIINVLNKE-DPDWWKGEVNGQVGLFPSNYVKL 1211
Score = 43.9 bits (102), Expect = 7e-05
Identities = 37/173 (21%), Positives = 63/173 (36%), Gaps = 50/173 (28%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPFG 61
E IA Y ++++ +L+F++GD++ V + D +W+ + K G P NY+ +K
Sbjct: 1006 EFIAMYTYESSEQGDLTFQQGDVILVTKK--DGDWWTGTVGDKAGVFPSNYVRLKD---- 1059
Query: 62 NDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQ 121
+G+G K SL ++P Q
Sbjct: 1060 ---------SEGSGT----AGKTGSLG--------------------------KKPEIAQ 1080
Query: 122 ALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHG-----QTGMFPRNYV 169
+ + +L G I + + WW+G Q G FP NYV
Sbjct: 1081 VIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYV 1133
Score = 42.7 bits (99), Expect = 2e-04
Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 6/59 (10%)
Query: 5 AKYDFKATADDELSFKRGDILKVLNEECDQN------WYKAELNGKDGFIPKNYIEMKP 57
A Y F++ + DE++ + GDI+ V E D++ W EL GK G+ P NY E P
Sbjct: 747 ALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKIP 805
Score = 40.0 bits (92), Expect = 0.001
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 7/64 (10%)
Query: 119 YVQALFDFDPQEDGELGFRRGDFIHV----MDNS---DPNWWKGACHGQTGMFPRNYVTP 171
Y +AL+ F+ + E+ + GD + V +D S +P W G G+TG FP NY
Sbjct: 744 YYRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEK 803
Query: 172 VNRN 175
+ N
Sbjct: 804 IPEN 807
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 65.9 bits (159), Expect = 2e-11
Identities = 40/169 (23%), Positives = 79/169 (46%), Gaps = 29/169 (17%)
Query: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPF 60
++A A Y ++A D+ L+F + D++ VL ++ W+ E+ G+ G+ PK+Y+++ P
Sbjct: 916 LQAQALYPWRAKKDNHLNFNKNDVITVLEQQ--DMWWFGEVQGQKGWFPKSYVKLISGPI 973
Query: 61 GNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYV 120
+D S S + +++ + V ++
Sbjct: 974 RKSTS-------------------------MDSGSSESPASLKRVASPAAKPVVSGEEFI 1008
Query: 121 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
A++ ++ E G+L F++GD I ++ D +WW G + G+FP NYV
Sbjct: 1009 -AMYTYESSEQGDLTFQQGDVI-LVTKKDGDWWTGTVGDKAGVFPSNYV 1055
Score = 64.3 bits (155), Expect = 5e-11
Identities = 44/173 (25%), Positives = 76/173 (43%), Gaps = 48/173 (27%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKD-----GFIPKNYIEMK 56
+ IA Y AT ++L+ G ++ ++ ++ W++ EL + G+ P NY+
Sbjct: 1080 QVIASYT--ATGPEQLTLAPGQLI-LIRKKNPGGWWEGELQARGKKRQIGWFPANYV--- 1133
Query: 57 PHPFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQ 116
K+L G K + +ST+++ Q+
Sbjct: 1134 -----------KLLSPGTSKI-----------TPTEPPKSTALAAVCQVI---------- 1161
Query: 117 PTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
++D+ Q D EL F +G I+V++ DP+WWKG +GQ G+FP NYV
Sbjct: 1162 -----GMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYV 1209
Score = 59.7 bits (143), Expect = 1e-09
Identities = 25/54 (46%), Positives = 38/54 (70%), Gaps = 1/54 (1%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEM 55
+ I YD+ A DDEL+F +G I+ VLN+E D +W+K E+NG+ G P NY+++
Sbjct: 1159 QVIGMYDYTAQNDDELAFNKGQIINVLNKE-DPDWWKGEVNGQVGLFPSNYVKL 1211
Score = 43.9 bits (102), Expect = 7e-05
Identities = 37/173 (21%), Positives = 63/173 (36%), Gaps = 50/173 (28%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPFG 61
E IA Y ++++ +L+F++GD++ V + D +W+ + K G P NY+ +K
Sbjct: 1006 EFIAMYTYESSEQGDLTFQQGDVILVTKK--DGDWWTGTVGDKAGVFPSNYVRLKD---- 1059
Query: 62 NDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQ 121
+G+G K SL ++P Q
Sbjct: 1060 ---------SEGSGT----AGKTGSLG--------------------------KKPEIAQ 1080
Query: 122 ALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHG-----QTGMFPRNYV 169
+ + +L G I + + WW+G Q G FP NYV
Sbjct: 1081 VIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYV 1133
Score = 42.7 bits (99), Expect = 2e-04
Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 6/59 (10%)
Query: 5 AKYDFKATADDELSFKRGDILKVLNEECDQN------WYKAELNGKDGFIPKNYIEMKP 57
A Y F++ + DE++ + GDI+ V E D++ W EL GK G+ P NY E P
Sbjct: 747 ALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKIP 805
Score = 40.0 bits (92), Expect = 0.001
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 7/64 (10%)
Query: 119 YVQALFDFDPQEDGELGFRRGDFIHV----MDNS---DPNWWKGACHGQTGMFPRNYVTP 171
Y +AL+ F+ + E+ + GD + V +D S +P W G G+TG FP NY
Sbjct: 744 YYRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEK 803
Query: 172 VNRN 175
+ N
Sbjct: 804 IPEN 807
>gi|223468657 SH3-domain GRB2-like 3 [Homo sapiens]
Length = 347
Score = 65.1 bits (157), Expect = 3e-11
Identities = 25/57 (43%), Positives = 37/57 (64%)
Query: 113 VPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
+P + L+DF+P+ GELGF+ GD I + + D NW++G HG++G FP NYV
Sbjct: 283 IPMDQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYV 339
Score = 53.1 bits (126), Expect = 1e-07
Identities = 22/49 (44%), Positives = 33/49 (67%), Gaps = 1/49 (2%)
Query: 7 YDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEM 55
YDF+ EL FK GDI+ + N+ D+NWY+ ++G+ GF P NY+E+
Sbjct: 294 YDFEPENQGELGFKEGDIITLTNQ-IDENWYEGMIHGESGFFPINYVEV 341
>gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens]
Length = 352
Score = 64.7 bits (156), Expect = 4e-11
Identities = 25/49 (51%), Positives = 36/49 (73%)
Query: 121 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
+AL+DF+P+ +GELGF+ GD I + + D NW++G HG +G FP NYV
Sbjct: 296 RALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGHSGFFPINYV 344
Score = 54.7 bits (130), Expect = 4e-08
Identities = 24/51 (47%), Positives = 34/51 (66%), Gaps = 1/51 (1%)
Query: 5 AKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEM 55
A YDF+ + EL FK GDI+ + N+ D+NWY+ L+G GF P NY+E+
Sbjct: 297 ALYDFEPENEGELGFKEGDIITLTNQ-IDENWYEGMLHGHSGFFPINYVEI 346
>gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens]
Length = 731
Score = 64.7 bits (156), Expect = 4e-11
Identities = 43/170 (25%), Positives = 81/170 (47%), Gaps = 31/170 (18%)
Query: 4 IAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE-MKPHP-FG 61
+A++++ DELSF G+I+ +L E ++ W + E+ G+ G P N++E ++ +P G
Sbjct: 518 VARFEYIGEQKDELSFSEGEII-ILKEYVNEEWARGEVRGRTGIFPLNFVEPVEDYPTSG 576
Query: 62 NDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQ 121
+V KV + + S S +Q + +P + + +
Sbjct: 577 ANVLSTKV--------------------PLKTKKEDSGSNSQ------VNSLPAE--WCE 608
Query: 122 ALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTP 171
AL F + +L F+RGD I +++ D +W +G + G+FP +V P
Sbjct: 609 ALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREGIFPAVFVRP 658
Score = 63.5 bits (153), Expect = 9e-11
Identities = 41/165 (24%), Positives = 69/165 (41%), Gaps = 48/165 (29%)
Query: 5 AKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPFGNDV 64
A + F A D+LSFKRGD +++L E D +W + L ++G P ++ P
Sbjct: 609 ALHSFTAETSDDLSFKRGDRIQIL-ERLDSDWCRGRLQDREGIFPAVFVRPCP------- 660
Query: 65 QHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALF 124
+ S+ +V R +AL+
Sbjct: 661 -----------------AEAKSMLAIVPKGRKA-----------------------KALY 680
Query: 125 DFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
DF + + EL F+ GD I +++ D +W G G++G+FP+NY+
Sbjct: 681 DFRGENEDELSFKAGDIITELESVDDDWMSGELMGKSGIFPKNYI 725
Score = 57.0 bits (136), Expect = 8e-09
Identities = 28/53 (52%), Positives = 34/53 (64%), Gaps = 1/53 (1%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE 54
+A A YDF+ +DELSFK GDI+ L E D +W EL GK G PKNYI+
Sbjct: 675 KAKALYDFRGENEDELSFKAGDIITEL-ESVDDDWMSGELMGKSGIFPKNYIQ 726
Score = 55.1 bits (131), Expect = 3e-08
Identities = 42/170 (24%), Positives = 72/170 (42%), Gaps = 41/170 (24%)
Query: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPFGN 62
A+ +DF A D+L+ G+I+ +L E+ D +WY+ + G P NY+++
Sbjct: 441 AVVLHDFPAEQVDDLNLTSGEIVYLL-EKIDTDWYRGNCRNQIGIFPANYVKVI------ 493
Query: 63 DVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQA 122
+ G GK E V H V ++ + A
Sbjct: 494 ----IDIPEGGNGK-----------RECVSSH---CVKGSRCV----------------A 519
Query: 123 LFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPV 172
F++ ++ EL F G+ I + + + W +G G+TG+FP N+V PV
Sbjct: 520 RFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNFVEPV 569
>gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens]
Length = 767
Score = 64.7 bits (156), Expect = 4e-11
Identities = 43/170 (25%), Positives = 81/170 (47%), Gaps = 31/170 (18%)
Query: 4 IAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE-MKPHP-FG 61
+A++++ DELSF G+I+ +L E ++ W + E+ G+ G P N++E ++ +P G
Sbjct: 554 VARFEYIGEQKDELSFSEGEII-ILKEYVNEEWARGEVRGRTGIFPLNFVEPVEDYPTSG 612
Query: 62 NDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQ 121
+V KV + + S S +Q + +P + + +
Sbjct: 613 ANVLSTKV--------------------PLKTKKEDSGSNSQ------VNSLPAE--WCE 644
Query: 122 ALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTP 171
AL F + +L F+RGD I +++ D +W +G + G+FP +V P
Sbjct: 645 ALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREGIFPAVFVRP 694
Score = 63.5 bits (153), Expect = 9e-11
Identities = 41/165 (24%), Positives = 69/165 (41%), Gaps = 48/165 (29%)
Query: 5 AKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPFGNDV 64
A + F A D+LSFKRGD +++L E D +W + L ++G P ++ P
Sbjct: 645 ALHSFTAETSDDLSFKRGDRIQIL-ERLDSDWCRGRLQDREGIFPAVFVRPCP------- 696
Query: 65 QHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALF 124
+ S+ +V R +AL+
Sbjct: 697 -----------------AEAKSMLAIVPKGRKA-----------------------KALY 716
Query: 125 DFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
DF + + EL F+ GD I +++ D +W G G++G+FP+NY+
Sbjct: 717 DFRGENEDELSFKAGDIITELESVDDDWMSGELMGKSGIFPKNYI 761
Score = 57.0 bits (136), Expect = 8e-09
Identities = 28/53 (52%), Positives = 34/53 (64%), Gaps = 1/53 (1%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE 54
+A A YDF+ +DELSFK GDI+ L E D +W EL GK G PKNYI+
Sbjct: 711 KAKALYDFRGENEDELSFKAGDIITEL-ESVDDDWMSGELMGKSGIFPKNYIQ 762
Score = 55.1 bits (131), Expect = 3e-08
Identities = 42/170 (24%), Positives = 72/170 (42%), Gaps = 41/170 (24%)
Query: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPFGN 62
A+ +DF A D+L+ G+I+ +L E+ D +WY+ + G P NY+++
Sbjct: 477 AVVLHDFPAEQVDDLNLTSGEIVYLL-EKIDTDWYRGNCRNQIGIFPANYVKVI------ 529
Query: 63 DVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQA 122
+ G GK E V H V ++ + A
Sbjct: 530 ----IDIPEGGNGK-----------RECVSSH---CVKGSRCV----------------A 555
Query: 123 LFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPV 172
F++ ++ EL F G+ I + + + W +G G+TG+FP N+V PV
Sbjct: 556 RFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNFVEPV 605
>gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens]
Length = 790
Score = 64.7 bits (156), Expect = 4e-11
Identities = 43/170 (25%), Positives = 81/170 (47%), Gaps = 31/170 (18%)
Query: 4 IAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE-MKPHP-FG 61
+A++++ DELSF G+I+ +L E ++ W + E+ G+ G P N++E ++ +P G
Sbjct: 577 VARFEYIGEQKDELSFSEGEII-ILKEYVNEEWARGEVRGRTGIFPLNFVEPVEDYPTSG 635
Query: 62 NDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQ 121
+V KV + + S S +Q + +P + + +
Sbjct: 636 ANVLSTKV--------------------PLKTKKEDSGSNSQ------VNSLPAE--WCE 667
Query: 122 ALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTP 171
AL F + +L F+RGD I +++ D +W +G + G+FP +V P
Sbjct: 668 ALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREGIFPAVFVRP 717
Score = 63.5 bits (153), Expect = 9e-11
Identities = 41/165 (24%), Positives = 69/165 (41%), Gaps = 48/165 (29%)
Query: 5 AKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPFGNDV 64
A + F A D+LSFKRGD +++L E D +W + L ++G P ++ P
Sbjct: 668 ALHSFTAETSDDLSFKRGDRIQIL-ERLDSDWCRGRLQDREGIFPAVFVRPCP------- 719
Query: 65 QHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALF 124
+ S+ +V R +AL+
Sbjct: 720 -----------------AEAKSMLAIVPKGRKA-----------------------KALY 739
Query: 125 DFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169
DF + + EL F+ GD I +++ D +W G G++G+FP+NY+
Sbjct: 740 DFRGENEDELSFKAGDIITELESVDDDWMSGELMGKSGIFPKNYI 784
Score = 57.0 bits (136), Expect = 8e-09
Identities = 28/53 (52%), Positives = 34/53 (64%), Gaps = 1/53 (1%)
Query: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE 54
+A A YDF+ +DELSFK GDI+ L E D +W EL GK G PKNYI+
Sbjct: 734 KAKALYDFRGENEDELSFKAGDIITEL-ESVDDDWMSGELMGKSGIFPKNYIQ 785
Score = 55.1 bits (131), Expect = 3e-08
Identities = 42/170 (24%), Positives = 72/170 (42%), Gaps = 41/170 (24%)
Query: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPFGN 62
A+ +DF A D+L+ G+I+ +L E+ D +WY+ + G P NY+++
Sbjct: 500 AVVLHDFPAEQVDDLNLTSGEIVYLL-EKIDTDWYRGNCRNQIGIFPANYVKVI------ 552
Query: 63 DVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQA 122
+ G GK E V H V ++ + A
Sbjct: 553 ----IDIPEGGNGK-----------RECVSSH---CVKGSRCV----------------A 578
Query: 123 LFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPV 172
F++ ++ EL F G+ I + + + W +G G+TG+FP N+V PV
Sbjct: 579 RFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNFVEPV 628
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.139 0.443
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,988,986
Number of Sequences: 37866
Number of extensions: 305354
Number of successful extensions: 1531
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 255
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 523
Number of HSP's gapped (non-prelim): 725
length of query: 176
length of database: 18,247,518
effective HSP length: 95
effective length of query: 81
effective length of database: 14,650,248
effective search space: 1186670088
effective search space used: 1186670088
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.