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Search of human proteins with 45356743
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45356743 SET domain-containing 8 [Homo sapiens]
(352 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45356743 SET domain-containing 8 [Homo sapiens] 711 0.0
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 78 1e-14
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 70 4e-12
gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens] 67 2e-11
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 65 7e-11
gi|19923202 enhancer of zeste homolog 1 [Homo sapiens] 65 7e-11
gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens] 64 2e-10
gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens] 64 2e-10
gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens] 64 3e-10
gi|197313748 SET domain containing 2 [Homo sapiens] 62 1e-09
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 60 2e-09
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 60 2e-09
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 60 2e-09
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor... 60 2e-09
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 58 1e-08
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 58 1e-08
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 58 1e-08
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens] 55 1e-07
gi|55741677 SET domain containing 1A [Homo sapiens] 54 2e-07
gi|27477095 nuclear receptor binding SET domain protein 1 isofor... 53 5e-07
gi|19923586 nuclear receptor binding SET domain protein 1 isofor... 53 5e-07
gi|210032580 SET domain containing 1B [Homo sapiens] 52 6e-07
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens] 52 6e-07
gi|224465233 euchromatic histone-lysine N-methyltransferase 1 is... 50 2e-06
gi|194306650 SET domain and mariner transposase fusion [Homo sap... 50 3e-06
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 39 0.005
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 39 0.005
gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [... 39 0.005
gi|24431975 hypothetical protein LOC26148 [Homo sapiens] 37 0.020
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 37 0.035
>gi|45356743 SET domain-containing 8 [Homo sapiens]
Length = 352
Score = 711 bits (1836), Expect = 0.0
Identities = 352/352 (100%), Positives = 352/352 (100%)
Query: 1 MARGRKMSKPRAVEAAAAAAAVAATAPGPEMVERRGPGRPRTDGENVFTGQSKIYSYMSP 60
MARGRKMSKPRAVEAAAAAAAVAATAPGPEMVERRGPGRPRTDGENVFTGQSKIYSYMSP
Sbjct: 1 MARGRKMSKPRAVEAAAAAAAVAATAPGPEMVERRGPGRPRTDGENVFTGQSKIYSYMSP 60
Query: 61 NKCSGMRFPLQEENSVTHHEVKCQGKPLAGIYRKREEKRNAGNAVRSAMKSEEQKIKDAR 120
NKCSGMRFPLQEENSVTHHEVKCQGKPLAGIYRKREEKRNAGNAVRSAMKSEEQKIKDAR
Sbjct: 61 NKCSGMRFPLQEENSVTHHEVKCQGKPLAGIYRKREEKRNAGNAVRSAMKSEEQKIKDAR 120
Query: 121 KGPLVPFPNQKSEAAEPPKTPPSSCDSTNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRK 180
KGPLVPFPNQKSEAAEPPKTPPSSCDSTNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRK
Sbjct: 121 KGPLVPFPNQKSEAAEPPKTPPSSCDSTNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRK 180
Query: 181 LTDFYPVRRSSRKSKAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGD 240
LTDFYPVRRSSRKSKAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGD
Sbjct: 181 LTDFYPVRRSSRKSKAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGD 240
Query: 241 FVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHS 300
FVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHS
Sbjct: 241 FVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHS 300
Query: 301 KCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGDRSKASIEAHPWLKH 352
KCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGDRSKASIEAHPWLKH
Sbjct: 301 KCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGDRSKASIEAHPWLKH 352
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 77.8 bits (190), Expect = 1e-14
Identities = 61/212 (28%), Positives = 95/212 (44%), Gaps = 19/212 (8%)
Query: 129 NQKSEAAEPPKTPPSSCDSTNAAIAKQALKK----PIKGKQAPRKKAQGKTQQNRKLTDF 184
++ EA EPP P S + + K A K +Q P + ++ +L
Sbjct: 3748 HKPEEANEPPLNPHGSARA-EVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQL--- 3803
Query: 185 YPVRRSSRKSKAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVE 244
+ + R + +L R R ++ +E + + GRG+ + G+ V+E
Sbjct: 3804 ---KSARRATSMDLPMPMRFRH---LKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIE 3857
Query: 245 YHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGN 304
Y G++I KRE Y GCYM+ + + VDAT N R INHS N
Sbjct: 3858 YAGNVIRSIQTDKREKYY-DSKGIGCYMFR---IDDSEVVDATMHGNA-ARFINHSCEPN 3912
Query: 305 CQTKLHDIDGVPHLILIASRDIAAGEELLYDY 336
C +++ +IDG H+++ A R I GEEL YDY
Sbjct: 3913 CYSRVINIDGQKHIVIFAMRKIYRGEELTYDY 3944
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 69.7 bits (169), Expect = 4e-12
Identities = 41/110 (37%), Positives = 55/110 (50%), Gaps = 5/110 (4%)
Query: 227 GRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDA 286
GRG+ + G+ V+EY G +I KRE Y GCYM+ VDA
Sbjct: 2586 GRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFY-DGKGIGCYMFRMDDFD---VVDA 2641
Query: 287 TRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDY 336
T N R INHS NC +++ ++G H+++ A R I GEEL YDY
Sbjct: 2642 TMHGNA-ARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDY 2690
Score = 30.0 bits (66), Expect = 3.3
Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 4/72 (5%)
Query: 101 AGNAVRSAMKSEEQKIKDAR----KGPLVPFPNQKSEAAEPPKTPPSSCDSTNAAIAKQA 156
A +++RSA++S+ + R K +P P A PPKTP QA
Sbjct: 133 APSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARKRGEEGTERMVQA 192
Query: 157 LKKPIKGKQAPR 168
L + ++ QAP+
Sbjct: 193 LTELLRRAQAPQ 204
Score = 28.9 bits (63), Expect = 7.3
Identities = 14/27 (51%), Positives = 15/27 (55%)
Query: 18 AAAAVAATAPGPEMVERRGPGRPRTDG 44
AAAA + PGP R PGRPR G
Sbjct: 2 AAAAGGGSCPGPGSARGRFPGRPRGAG 28
>gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens]
Length = 412
Score = 67.4 bits (163), Expect = 2e-11
Identities = 43/131 (32%), Positives = 69/131 (52%), Gaps = 12/131 (9%)
Query: 215 EEGMKIDLI-----DGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTG 269
++G++ DL DG+G GV ++ + FV+EY G++I +A++R +Y + +T
Sbjct: 238 QKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGAT- 296
Query: 270 CYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDG----VPHLILIASRD 325
Y++ Y+ Y VDA N + +NHS N Q ID +P + A+R
Sbjct: 297 -YLFDLDYVEDVYTVDAAYYGN-ISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRT 354
Query: 326 IAAGEELLYDY 336
I AGEEL +DY
Sbjct: 355 IRAGEELTFDY 365
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 65.5 bits (158), Expect = 7e-11
Identities = 40/111 (36%), Positives = 60/111 (54%), Gaps = 5/111 (4%)
Query: 226 KGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVD 285
+G G+ A K + V+EY G +I A +RE +Y ++ + G YM+ ++ + +D
Sbjct: 5407 QGLGLYAAKDLEKHTMVIEYIGTIIRNEVANRREKIY-EEQNRGIYMFR---INNEHVID 5462
Query: 286 ATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDY 336
AT T R INHS NC ++ D +I+I+SR I GEEL YDY
Sbjct: 5463 ATL-TGGPARYINHSCAPNCVAEVVTFDKEDKIIIISSRRIPKGEELTYDY 5512
>gi|19923202 enhancer of zeste homolog 1 [Homo sapiens]
Length = 747
Score = 65.5 bits (158), Expect = 7e-11
Identities = 42/128 (32%), Positives = 68/128 (53%), Gaps = 8/128 (6%)
Query: 210 IESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTG 269
I+ G ++ + + D G G + + +F+ EY G+LI +A +R +Y +
Sbjct: 607 IQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDK----- 661
Query: 270 CYMYYFQY-LSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAA 328
YM F + L+ + VDATR+ N++ R NHS NC K+ ++G + + A R I A
Sbjct: 662 -YMSSFLFNLNNDFVVDATRKGNKI-RFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQA 719
Query: 329 GEELLYDY 336
GEEL +DY
Sbjct: 720 GEELFFDY 727
>gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens]
Length = 707
Score = 64.3 bits (155), Expect = 2e-10
Identities = 40/128 (31%), Positives = 67/128 (52%), Gaps = 8/128 (6%)
Query: 210 IESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTG 269
I+ G ++ + + D G G+ + +F+ EY G++I +A +R +Y +
Sbjct: 567 IQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDK----- 621
Query: 270 CYMYYFQY-LSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAA 328
YM F + L+ + VDATR+ N++ R NHS NC K+ ++G + + A R I
Sbjct: 622 -YMCSFLFNLNNDFVVDATRKGNKI-RFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQT 679
Query: 329 GEELLYDY 336
GEEL +DY
Sbjct: 680 GEELFFDY 687
>gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens]
Length = 751
Score = 64.3 bits (155), Expect = 2e-10
Identities = 40/128 (31%), Positives = 67/128 (52%), Gaps = 8/128 (6%)
Query: 210 IESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTG 269
I+ G ++ + + D G G+ + +F+ EY G++I +A +R +Y +
Sbjct: 611 IQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDK----- 665
Query: 270 CYMYYFQY-LSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAA 328
YM F + L+ + VDATR+ N++ R NHS NC K+ ++G + + A R I
Sbjct: 666 -YMCSFLFNLNNDFVVDATRKGNKI-RFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQT 723
Query: 329 GEELLYDY 336
GEEL +DY
Sbjct: 724 GEELFFDY 731
>gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens]
Length = 350
Score = 63.5 bits (153), Expect = 3e-10
Identities = 47/134 (35%), Positives = 67/134 (50%), Gaps = 12/134 (8%)
Query: 224 DGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYC 283
+G+G GV + R FV+EY G++I +A++R Y T Y++ Y S +
Sbjct: 199 NGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGIT--YLFDLDYESDEFT 256
Query: 284 VDATRETNRLGRLINHSKCGNCQTKLHDIDG----VPHLILIASRDIAAGEELLYDY--- 336
VDA R N + +NHS N Q ID +P + L ++R I AGEEL +DY
Sbjct: 257 VDAARYGN-VSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMK 315
Query: 337 --GDRSKASIEAHP 348
GD S SI+ P
Sbjct: 316 GSGDISSDSIDHSP 329
>gi|197313748 SET domain containing 2 [Homo sapiens]
Length = 2564
Score = 61.6 bits (148), Expect = 1e-09
Identities = 48/175 (27%), Positives = 84/175 (48%), Gaps = 14/175 (8%)
Query: 162 KGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKRIDELIESGKEEGMKID 221
K ++A + A G+ NR L + SSR + S R + + +++
Sbjct: 1506 KDERAQGEIACGEDCLNRLLM----IECSSRCPNGDYCSNRR------FQRKQHADVEVI 1555
Query: 222 LIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKT 281
L + KG G+ A K FV+EY G++++ + K R YA++ + YYF L
Sbjct: 1556 LTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKN---IHYYFMALKND 1612
Query: 282 YCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDY 336
+DAT++ N R +NHS NC+T+ ++G + ++ + +G EL +DY
Sbjct: 1613 EIIDATQKGN-CSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDY 1666
>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 60.5 bits (145), Expect = 2e-09
Identities = 41/118 (34%), Positives = 61/118 (51%), Gaps = 4/118 (3%)
Query: 219 KIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYL 278
KI DGKG G++A + +G+FV EY G+LI+ + R ++ T YM +
Sbjct: 1066 KIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYML---TI 1122
Query: 279 SKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDY 336
K +DA + N R +NHS NC+T ++G + L A DI AG EL ++Y
Sbjct: 1123 DKDRIIDAGPKGN-YSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNY 1179
>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 60.5 bits (145), Expect = 2e-09
Identities = 41/118 (34%), Positives = 61/118 (51%), Gaps = 4/118 (3%)
Query: 219 KIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYL 278
KI DGKG G++A + +G+FV EY G+LI+ + R ++ T YM +
Sbjct: 1066 KIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYML---TI 1122
Query: 279 SKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDY 336
K +DA + N R +NHS NC+T ++G + L A DI AG EL ++Y
Sbjct: 1123 DKDRIIDAGPKGN-YSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNY 1179
>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 60.5 bits (145), Expect = 2e-09
Identities = 41/118 (34%), Positives = 61/118 (51%), Gaps = 4/118 (3%)
Query: 219 KIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYL 278
KI DGKG G++A + +G+FV EY G+LI+ + R ++ T YM +
Sbjct: 1066 KIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYML---TI 1122
Query: 279 SKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDY 336
K +DA + N R +NHS NC+T ++G + L A DI AG EL ++Y
Sbjct: 1123 DKDRIIDAGPKGN-YSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNY 1179
>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 60.5 bits (145), Expect = 2e-09
Identities = 41/118 (34%), Positives = 61/118 (51%), Gaps = 4/118 (3%)
Query: 219 KIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYL 278
KI DGKG G++A + +G+FV EY G+LI+ + R ++ T YM +
Sbjct: 1066 KIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYML---TI 1122
Query: 279 SKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDY 336
K +DA + N R +NHS NC+T ++G + L A DI AG EL ++Y
Sbjct: 1123 DKDRIIDAGPKGN-YSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNY 1179
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 58.2 bits (139), Expect = 1e-08
Identities = 37/111 (33%), Positives = 57/111 (51%), Gaps = 5/111 (4%)
Query: 226 KGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVD 285
+G G+ A + + V+EY G +I A ++E LY + + G YM+ + + +D
Sbjct: 4781 QGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLY-ESQNRGVYMFR---MDNDHVID 4836
Query: 286 ATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDY 336
AT T R INHS NC ++ + +I+ +SR I GEEL YDY
Sbjct: 4837 ATL-TGGPARYINHSCAPNCVAEVVTFERGHKIIISSSRRIQKGEELCYDY 4886
Score = 28.5 bits (62), Expect = 9.5
Identities = 12/25 (48%), Positives = 15/25 (60%)
Query: 24 ATAPGPEMVERRGPGRPRTDGENVF 48
A AP P ++R GRPR DG + F
Sbjct: 24 APAPSPAAADKRPRGRPRKDGASPF 48
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2 isoform
b [Homo sapiens]
Length = 1176
Score = 57.8 bits (138), Expect = 1e-08
Identities = 45/140 (32%), Positives = 65/140 (46%), Gaps = 18/140 (12%)
Query: 207 DELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREA---LYA 263
+ +++SG + +++ G GV A + +G F+ EY G+LI +A RE L+
Sbjct: 995 NRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFD 1054
Query: 264 QDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQT----KLHDIDGVPHLI 319
D G + YC+DA R + R INH N LH P +
Sbjct: 1055 LDNKDG----------EVYCIDA-RYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIA 1103
Query: 320 LIASRDIAAGEELLYDYGDR 339
+SRDI GEEL +DYGDR
Sbjct: 1104 FFSSRDIRTGEELGFDYGDR 1123
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2 isoform
a [Homo sapiens]
Length = 1210
Score = 57.8 bits (138), Expect = 1e-08
Identities = 45/140 (32%), Positives = 65/140 (46%), Gaps = 18/140 (12%)
Query: 207 DELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREA---LYA 263
+ +++SG + +++ G GV A + +G F+ EY G+LI +A RE L+
Sbjct: 1029 NRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFD 1088
Query: 264 QDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQT----KLHDIDGVPHLI 319
D G + YC+DA R + R INH N LH P +
Sbjct: 1089 LDNKDG----------EVYCIDA-RYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIA 1137
Query: 320 LIASRDIAAGEELLYDYGDR 339
+SRDI GEEL +DYGDR
Sbjct: 1138 FFSSRDIRTGEELGFDYGDR 1157
>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
Length = 2964
Score = 54.7 bits (130), Expect = 1e-07
Identities = 35/115 (30%), Positives = 55/115 (47%), Gaps = 5/115 (4%)
Query: 226 KGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVD 285
KG G+ + G F++EY G+++ + + R + S +Y L +D
Sbjct: 2150 KGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSD----HYCLNLDSGMVID 2205
Query: 286 ATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGDRS 340
+ R N R INHS NC+ + ++GV + L A +D+ AG EL YDY S
Sbjct: 2206 SYRMGNE-ARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHS 2259
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 54.3 bits (129), Expect = 2e-07
Identities = 47/181 (25%), Positives = 79/181 (43%), Gaps = 15/181 (8%)
Query: 160 PIKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKRIDELIESGKEEGMK 219
P+ +Q QG NR L++ RRS ++ +L++ + + K
Sbjct: 1515 PVSARQLEGVDTQGT---NRVLSE----RRSEQRRLLSAIGTSAIMDSDLLKLNQLKFRK 1567
Query: 220 IDLIDGKGR----GVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYF 275
L G+ R G+ A + + + V+EY G I A RE Y Q+ Y++
Sbjct: 1568 KKLRFGRSRIHEWGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSYLFRV 1627
Query: 276 QYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYD 335
+ + +DAT+ N L R INH NC K+ I+ +++ + + I EE+ YD
Sbjct: 1628 DHDT---IIDATKCGN-LARFINHCCTPNCYAKVITIESQKKIVIYSKQPIGVDEEITYD 1683
Query: 336 Y 336
Y
Sbjct: 1684 Y 1684
>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
[Homo sapiens]
Length = 2427
Score = 52.8 bits (125), Expect = 5e-07
Identities = 36/111 (32%), Positives = 56/111 (50%), Gaps = 4/111 (3%)
Query: 226 KGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVD 285
+G G+ +G+FV EY G+LI+ + + R YAQ+ +Y L K +D
Sbjct: 1683 RGWGLRTKTDIKKGEFVNEYVGELIDEEECRAR-IRYAQEHDIT--NFYMLTLDKDRIID 1739
Query: 286 ATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDY 336
A + N R +NH NC+T+ ++G + L A DI AG EL ++Y
Sbjct: 1740 AGPKGN-YARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNY 1789
>gi|19923586 nuclear receptor binding SET domain protein 1 isoform b
[Homo sapiens]
Length = 2696
Score = 52.8 bits (125), Expect = 5e-07
Identities = 36/111 (32%), Positives = 56/111 (50%), Gaps = 4/111 (3%)
Query: 226 KGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVD 285
+G G+ +G+FV EY G+LI+ + + R YAQ+ +Y L K +D
Sbjct: 1952 RGWGLRTKTDIKKGEFVNEYVGELIDEEECRAR-IRYAQEHDIT--NFYMLTLDKDRIID 2008
Query: 286 ATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDY 336
A + N R +NH NC+T+ ++G + L A DI AG EL ++Y
Sbjct: 2009 AGPKGN-YARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNY 2058
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 52.4 bits (124), Expect = 6e-07
Identities = 38/159 (23%), Positives = 72/159 (45%), Gaps = 16/159 (10%)
Query: 190 SSRKSKAELQSEERKRIDELIESGKEEGMKIDLIDGKGR------------GVIATKQFS 237
+S ++ +E +SE+R+ + S + +K + + + + G+ A + +
Sbjct: 1746 ASTRAGSERRSEQRRLLSSFTGSCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFAMEPIA 1805
Query: 238 RGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLI 297
+ V+EY G I A RE Y + YM+ + + +DAT+ N R I
Sbjct: 1806 ADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHDT---IIDATKCGN-FARFI 1861
Query: 298 NHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDY 336
NHS NC K+ ++ +++ + + I EE+ YDY
Sbjct: 1862 NHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDY 1900
>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
Length = 1437
Score = 52.4 bits (124), Expect = 6e-07
Identities = 35/111 (31%), Positives = 58/111 (52%), Gaps = 4/111 (3%)
Query: 226 KGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVD 285
+G G+ + +G+FV EY G+LI+ + + R ++ T YM ++K +D
Sbjct: 1155 RGWGLRTKRSIKKGEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLT---VTKDRIID 1211
Query: 286 ATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDY 336
A + N R +NHS NC+T+ ++G + L A DI AG EL ++Y
Sbjct: 1212 AGPKGN-YSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAGMELTFNY 1261
>gi|224465233 euchromatic histone-lysine N-methyltransferase 1 isoform
1 [Homo sapiens]
Length = 1298
Score = 50.4 bits (119), Expect = 2e-06
Identities = 41/144 (28%), Positives = 66/144 (45%), Gaps = 26/144 (18%)
Query: 207 DELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREA---LYA 263
+ ++++G +++ G GV + + G FV EY G+LI ++A RE L+
Sbjct: 1117 NRVVQNGLRARLQLYRTRDMGWGVRSLQDIPPGTFVCEYVGELISDSEADVREEDSYLFD 1176
Query: 264 QDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKL--------HDIDGV 315
D G + YC+DA R + R INH +C+ L H
Sbjct: 1177 LDNKDG----------EVYCIDA-RFYGNVSRFINH----HCEPNLVPVRVFMAHQDLRF 1221
Query: 316 PHLILIASRDIAAGEELLYDYGDR 339
P + ++R I AGE+L +DYG+R
Sbjct: 1222 PRIAFFSTRLIEAGEQLGFDYGER 1245
>gi|194306650 SET domain and mariner transposase fusion [Homo
sapiens]
Length = 684
Score = 50.1 bits (118), Expect = 3e-06
Identities = 42/140 (30%), Positives = 69/140 (49%), Gaps = 11/140 (7%)
Query: 207 DELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDP 266
+ +++ G + ++ KG G+ + +G FV EY G+++ ++ ++R ++ Q
Sbjct: 130 NRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRR--IHLQTK 187
Query: 267 STGCYMY------YFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDG-VPHLI 319
S Y+ Y + +T+ VD T N +GR +NHS N ID VP L
Sbjct: 188 SDSNYIIAIREHVYNGQVMETF-VDPTYIGN-IGRFLNHSCEPNLLMIPVRIDSMVPKLA 245
Query: 320 LIASRDIAAGEELLYDYGDR 339
L A++DI EEL YDY R
Sbjct: 246 LFAAKDIVPEEELSYDYSGR 265
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 39.3 bits (90), Expect = 0.005
Identities = 36/150 (24%), Positives = 70/150 (46%), Gaps = 18/150 (12%)
Query: 70 LQEENSVTHHEVKCQGKPLAGIYRKREEKRNAGNAVRSAMKSEEQKIKDARKGPLVPFPN 129
LQE+ H ++ +P +K+E+ K E++K K RK + N
Sbjct: 514 LQEQLKAVHEQLAALSQPQQNKPKKKEKD-----------KKEKKKEKHKRKEEVEE--N 560
Query: 130 QKSEAAEPPKTPPSSCDSTNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRKLTDFYPVRR 189
+KS+A EPP +S+N+ ++K+ P+K K P +++ ++++ Y +R
Sbjct: 561 KKSKAKEPPPKKTKKNNSSNSNVSKKE-PAPMKSKPPPTYESE---EEDKCKPMSYEEKR 616
Query: 190 SSRKSKAELQSEERKRIDELIESGKEEGMK 219
+L E+ R+ +I+S +E +K
Sbjct: 617 QLSLDINKLPGEKLGRVVHIIQS-REPSLK 645
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 39.3 bits (90), Expect = 0.005
Identities = 36/150 (24%), Positives = 70/150 (46%), Gaps = 18/150 (12%)
Query: 70 LQEENSVTHHEVKCQGKPLAGIYRKREEKRNAGNAVRSAMKSEEQKIKDARKGPLVPFPN 129
LQE+ H ++ +P +K+E+ K E++K K RK + N
Sbjct: 514 LQEQLKAVHEQLAALSQPQQNKPKKKEKD-----------KKEKKKEKHKRKEEVEE--N 560
Query: 130 QKSEAAEPPKTPPSSCDSTNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRKLTDFYPVRR 189
+KS+A EPP +S+N+ ++K+ P+K K P +++ ++++ Y +R
Sbjct: 561 KKSKAKEPPPKKTKKNNSSNSNVSKKE-PAPMKSKPPPTYESE---EEDKCKPMSYEEKR 616
Query: 190 SSRKSKAELQSEERKRIDELIESGKEEGMK 219
+L E+ R+ +I+S +E +K
Sbjct: 617 QLSLDINKLPGEKLGRVVHIIQS-REPSLK 645
Score = 31.6 bits (70), Expect = 1.1
Identities = 29/130 (22%), Positives = 51/130 (39%), Gaps = 4/130 (3%)
Query: 39 RPRTDGENVFTGQSKIYSYMSP-NKCSGMRFPLQEENSVTHHEVKCQGKPLAGIYRKREE 97
+P+ + +V G SK+ + S ++ S E+S T K + K G +K+
Sbjct: 680 KPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHH 739
Query: 98 KRNAGNAVRSAMKSEEQKIKDARKGPLVPFPNQKSEAAEPPKTPPSSCDSTNAAIAKQAL 157
+ ++ +Q ++ P P P Q+ + PP PP AA A ++
Sbjct: 740 HHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQ---PPPPPPPPSMPQQAAPAMKSS 796
Query: 158 KKPIKGKQAP 167
P Q P
Sbjct: 797 PPPFIATQVP 806
>gi|54112382 F-box and leucine-rich repeat protein 10 isoform a
[Homo sapiens]
Length = 1336
Score = 39.3 bits (90), Expect = 0.005
Identities = 40/179 (22%), Positives = 76/179 (42%), Gaps = 16/179 (8%)
Query: 38 GRPRTDGENVFTGQSKIYSYMSPNKCSGMRFPLQEENSVTHHEVKCQGKPLAGIYRKREE 97
GR R G S S++SP G +S+T+ + + + ++RK+
Sbjct: 814 GRKRASSLQTSPGSS---SHLSPRPPLGSSLSPWWRSSLTYFQQQLKPGKEDKLFRKK-- 868
Query: 98 KRNAGNAVRSAMKSEEQKIKDARKGPLVPFPNQKSEAAEPPKTPPSSCDSTNAAIAKQAL 157
R + K+ E ++ A K PL F + + E P+ PP + +S ++ +
Sbjct: 869 --------RRSWKNAEDRMALANK-PLRRFKQEPED--ELPEAPPKTRESDHSRSSSPTA 917
Query: 158 KKPIKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKRIDELIESGKEE 216
+G + P +K + K ++ R+L + R S++ E+Q E +E + K E
Sbjct: 918 GPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSE 976
>gi|24431975 hypothetical protein LOC26148 [Homo sapiens]
Length = 1247
Score = 37.4 bits (85), Expect = 0.020
Identities = 37/189 (19%), Positives = 72/189 (38%), Gaps = 28/189 (14%)
Query: 58 MSPNKCSGMRFPLQEENSVTHHEVKCQGKPLAGIYRKREEKRNAGNAVRSAMKSEEQKIK 117
+ P GM+ ++ S + + Q K + +N G V++ S+E+
Sbjct: 1060 VKPKSTEGMKGRKGKQVSEILPKAEVQSKRKRTEGSSPPDSKNKGPTVKA---SKEKHAD 1116
Query: 118 DARKGPLVPFPNQKSEAAEPPKT-------------------PPSSCDSTNA------AI 152
A K P P + +++PPK PPS + N +I
Sbjct: 1117 GATKTPAAKRPAARDRSSQPPKKTSLKENKVKIPKKSAGKSCPPSRKEKENTNKRPSQSI 1176
Query: 153 AKQALKKPIKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKRIDELIES 212
A + L KP K K A ++ + NRK + R S K+ ++ ++++ ++
Sbjct: 1177 ASETLTKPAKQKGAGESSSRPQKATNRKQSSGKTRARPSTKTPESSAAQRKRKLKAKLDC 1236
Query: 213 GKEEGMKID 221
+ ++D
Sbjct: 1237 SHSKRRRLD 1245
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 36.6 bits (83), Expect = 0.035
Identities = 29/127 (22%), Positives = 57/127 (44%), Gaps = 16/127 (12%)
Query: 93 RKREEKRNAGNAVRSAMKSEEQKIKDARKGPLVPFPNQKSEAAEPPKTPPSSCDSTNAAI 152
R+R R G RS K+ ++K +D +K + PPK+ S+ + +A
Sbjct: 292 RRRSHSRERGRRSRSTSKTRDKKKED----------KEKKRSKTPPKSY-STARRSRSAS 340
Query: 153 AKQALKKPIKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKRIDELIES 212
++ ++ G ++P+K K + +R P R +K K + + +ER R + +
Sbjct: 341 RERRRRRSRSGTRSPKKPRSPKRKLSRS-----PSPRRHKKEKKKDKDKERSRDERERST 395
Query: 213 GKEEGMK 219
K++ K
Sbjct: 396 SKKKKSK 402
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,285,455
Number of Sequences: 37866
Number of extensions: 681727
Number of successful extensions: 3820
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 171
Number of HSP's that attempted gapping in prelim test: 3553
Number of HSP's gapped (non-prelim): 406
length of query: 352
length of database: 18,247,518
effective HSP length: 103
effective length of query: 249
effective length of database: 14,347,320
effective search space: 3572482680
effective search space used: 3572482680
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.