Guide to the Human Genome
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Search of human proteins with 45120115

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45120115 hypothetical protein LOC56905 [Homo sapiens]
         (1047 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45120115 hypothetical protein LOC56905 [Homo sapiens]             2179   0.0  
gi|163965366 nascent polypeptide-associated complex alpha subuni...   107   8e-23
gi|47132519 Ras association and pleckstrin homology domains 1 is...    91   6e-18
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    90   1e-17
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    90   1e-17
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ...    90   1e-17
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    89   3e-17
gi|150170670 piccolo isoform 2 [Homo sapiens]                          78   5e-14
gi|150378539 piccolo isoform 1 [Homo sapiens]                          78   5e-14
gi|116256464 hypothetical protein LOC343990 [Homo sapiens]             77   6e-14
gi|110349719 titin isoform N2-A [Homo sapiens]                         77   1e-13
gi|116284392 mucin 2 precursor [Homo sapiens]                          72   3e-12
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    72   4e-12
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom...    72   4e-12
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom...    72   4e-12
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap...    72   4e-12
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             72   4e-12
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    71   5e-12
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]                    71   5e-12
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   71   6e-12
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   71   6e-12
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   71   6e-12
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    71   6e-12
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    69   2e-11
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         69   2e-11
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          67   7e-11
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          67   7e-11
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          67   7e-11
gi|237757308 synaptojanin 1 isoform b [Homo sapiens]                   67   9e-11
gi|55750053 atrophin-1 [Homo sapiens]                                  66   2e-10

>gi|45120115 hypothetical protein LOC56905 [Homo sapiens]
          Length = 1047

 Score = 2179 bits (5645), Expect = 0.0
 Identities = 1047/1047 (100%), Positives = 1047/1047 (100%)

Query: 1    MAEKRPLRTLGPVMYGKLPRLETDSGLEHSLPHSVGNQDPCTYKGSYFSCPMAGTPKAES 60
            MAEKRPLRTLGPVMYGKLPRLETDSGLEHSLPHSVGNQDPCTYKGSYFSCPMAGTPKAES
Sbjct: 1    MAEKRPLRTLGPVMYGKLPRLETDSGLEHSLPHSVGNQDPCTYKGSYFSCPMAGTPKAES 60

Query: 61   EQLASWTPYPPLYSTGMAGPPLQADNLLTNCLFYRSPAEGPEKMQDSSPVELLPFSPQAH 120
            EQLASWTPYPPLYSTGMAGPPLQADNLLTNCLFYRSPAEGPEKMQDSSPVELLPFSPQAH
Sbjct: 61   EQLASWTPYPPLYSTGMAGPPLQADNLLTNCLFYRSPAEGPEKMQDSSPVELLPFSPQAH 120

Query: 121  SYPGPPLAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWTLATGPLLPSADPPCSLAPAP 180
            SYPGPPLAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWTLATGPLLPSADPPCSLAPAP
Sbjct: 121  SYPGPPLAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWTLATGPLLPSADPPCSLAPAP 180

Query: 181  SKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYPRNSKQ 240
            SKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYPRNSKQ
Sbjct: 181  SKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYPRNSKQ 240

Query: 241  AMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSP 300
            AMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSP
Sbjct: 241  AMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSP 300

Query: 301  ALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLE 360
            ALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLE
Sbjct: 301  ALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLE 360

Query: 361  PPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPL 420
            PPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPL
Sbjct: 361  PPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPL 420

Query: 421  PASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCA 480
            PASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCA
Sbjct: 421  PASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCA 480

Query: 481  RECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPAT 540
            RECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPAT
Sbjct: 481  RECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPAT 540

Query: 541  SEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPT 600
            SEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPT
Sbjct: 541  SEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPT 600

Query: 601  AAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPA 660
            AAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPA
Sbjct: 601  AAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPA 660

Query: 661  PLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPA 720
            PLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPA
Sbjct: 661  PLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPA 720

Query: 721  PAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQHFTGLHASLCDAISG 780
            PAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQHFTGLHASLCDAISG
Sbjct: 721  PAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQHFTGLHASLCDAISG 780

Query: 781  SVAHSPPEKLREWLETAGPWGQAAWQDCQGVQGLLAKLLSQLQRFDRTHRCPFPHVVRAG 840
            SVAHSPPEKLREWLETAGPWGQAAWQDCQGVQGLLAKLLSQLQRFDRTHRCPFPHVVRAG
Sbjct: 781  SVAHSPPEKLREWLETAGPWGQAAWQDCQGVQGLLAKLLSQLQRFDRTHRCPFPHVVRAG 840

Query: 841  AIFVPIHLVKERLFPRLPPASVDHVLQEHRVELRPTTLSEERALRELALPGCTSRMLKLL 900
            AIFVPIHLVKERLFPRLPPASVDHVLQEHRVELRPTTLSEERALRELALPGCTSRMLKLL
Sbjct: 841  AIFVPIHLVKERLFPRLPPASVDHVLQEHRVELRPTTLSEERALRELALPGCTSRMLKLL 900

Query: 901  ALRQLPDIYPDLLGLQWRDCVRRQLGDFDTEAGAVSSSEPTVARDEPESLALAQKSPAPK 960
            ALRQLPDIYPDLLGLQWRDCVRRQLGDFDTEAGAVSSSEPTVARDEPESLALAQKSPAPK
Sbjct: 901  ALRQLPDIYPDLLGLQWRDCVRRQLGDFDTEAGAVSSSEPTVARDEPESLALAQKSPAPK 960

Query: 961  VRKPGRKPPTPGPEKAEAAAGEESCGASPTPATSASPPGPTLKARFRSLLETAWLNGLAL 1020
            VRKPGRKPPTPGPEKAEAAAGEESCGASPTPATSASPPGPTLKARFRSLLETAWLNGLAL
Sbjct: 961  VRKPGRKPPTPGPEKAEAAAGEESCGASPTPATSASPPGPTLKARFRSLLETAWLNGLAL 1020

Query: 1021 PTWGHKSSRPDQPSPCPQLLDSQSHHL 1047
            PTWGHKSSRPDQPSPCPQLLDSQSHHL
Sbjct: 1021 PTWGHKSSRPDQPSPCPQLLDSQSHHL 1047


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score =  107 bits (266), Expect = 8e-23
 Identities = 173/713 (24%), Positives = 243/713 (34%), Gaps = 126/713 (17%)

Query: 98   AEGPEKMQDSSPVELLPFSPQAHSYPGPPLAAPKPVYRNPLCYGLSTCLGEGAVKRPLDV 157
            +  P+K + +   + +P SP     P PP A P      P     +T   + A   P   
Sbjct: 915  SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGP-----ATPSPKWAPTPPAAT 969

Query: 158  DWTLATGPLLPSAD----PPCSLAPAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQ-P 212
              +   GP  PS      PP +  P+P  G        +G P   +    S   SP   P
Sbjct: 970  PPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP--KGAPTPPAVTPPSPKGSPAATP 1027

Query: 213  FLEKYQTIHSTGFLASRYTGPYPRNSKQAM---SEGPSSPWTQLAQPLGPPCQDTGPTHY 269
            F +   T  +        T P P+ S  A       P++P   L  P G P   +     
Sbjct: 1028 FPKGASTPPAA-------TPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP 1080

Query: 270  PPPHHPPPHP--------PQALPCPPACRHPEKQGSYS-PALPLQPLGGHKGTGYQAGGL 320
             PP   PP P        P+  P PPA   P  +G  + P     P           GGL
Sbjct: 1081 TPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL 1140

Query: 321  GSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPY 380
             +P            PP G  A   P+A  P+P  GL   PP                  
Sbjct: 1141 ATP------------PPKG--APTTPAATPPSPKGGLATPPPK----------------- 1169

Query: 381  ARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKT 440
                    GA      TPPS     A P P    +     PA+ P      P+ +    T
Sbjct: 1170 --------GAPTTPAATPPSPKGGLATPSP----KGAPTTPAATP------PSPKGGLAT 1211

Query: 441  WLPSCRKEKLQPRLSEHSGPPIVIRDSP--VPCTPPALPPCARECQSLPQKEDARPPSSP 498
              PS +     P  +  S    +   SP   P TP A PP  +   + P  + A  P + 
Sbjct: 1212 --PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAA 1269

Query: 499  PMPVIDNVFSLAPYRDYLDVPAPEATTEPDS----ATAEPDSAP---ATSEGQDKGCRGT 551
              P +    +  P++     P P   T P      AT+ P  AP   A +    KG  GT
Sbjct: 1270 TPPSLKGGLATPPHKG---APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT 1326

Query: 552  LPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNM 611
             P +  P+       S K    L  +   P+++  P   S S E   P AA      G  
Sbjct: 1327 PPPKGAPTPPAVTPPSPKGTPTLPATT--PSSKGGPTTPS-SKEGPTPPAATPSHKGGPA 1383

Query: 612  VSDLPGLKKIDTEAPGLPG----------VPVTTDAMPRTNFHSSVAFMFRKFKILRPAP 661
            ++  P  K+     P +P           +P++    P T      A    K  +  PA 
Sbjct: 1384 MTP-PSPKR----GPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV 1438

Query: 662  LPAAVV-----------PSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPS 710
             P ++            P+TP+S   PT PA TP   P      A + ++ +      P+
Sbjct: 1439 TPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP---PSPKEPPAPKQVATSSSPKKAPA 1495

Query: 711  PPAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSL 763
             PA   A   PA  PS        P+S RDP    A +      +T AP ++L
Sbjct: 1496 TPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL 1548



 Score =  106 bits (265), Expect = 1e-22
 Identities = 206/785 (26%), Positives = 268/785 (34%), Gaps = 122/785 (15%)

Query: 40   PCTYKGSYFSCPMAGTPKAESEQLASWTPYPPLYSTGMAGPPLQADNLLTNCLFYRSPAE 99
            P + KGS  + P    PK  S   A+  P P       A  PL      T      SP  
Sbjct: 1016 PPSPKGSPAATPF---PKGASTPPAATPPSP---KGSPAATPLPKGAPTTPAATLPSPKG 1069

Query: 100  GPEKMQ---DSSPVELLPFSPQAHSYPGPPLAAPKPVYRNPLCY--GLSTCLGEGAVKRP 154
            GP         +P    P SP+       P  AP P    P     GL+T   +GA   P
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTP 1129

Query: 155  LDVDWT----LAT-----GPLLPSADPPC---SLAPAPSKGQTLDGTFLRGVPAEGSSKD 202
                 +    LAT      P  P+A PP     LA  P KG           P  G +  
Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1189

Query: 203  SSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYPRNSKQAMSEGPSSPWTQLAQPLGPPCQ 262
            S    +P  P           G LA+    P P+ +    +  P SP   LA P  P   
Sbjct: 1190 SPKG-APTTPAATPPSP---KGGLAT----PSPKGAPTTPAATPPSPKGGLATP-SPKGA 1240

Query: 263  DTGPTHYPPPHH--PPPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAGGL 320
             T P   PP     P   PP+  P PPA   P  +G     L   P   HKG    A  +
Sbjct: 1241 PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGG----LATPP---HKGAPNPAV-V 1292

Query: 321  GSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPY 380
              P  +   A +P   P G    P  + P P  SPG    PP     P    P     P 
Sbjct: 1293 TPPSPKGGPATSP---PKGAPTPPAATPPSPKGSPGTP--PPKGAPTPPAVTP-----PS 1342

Query: 381  ARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKT 440
             +   +L   +P   G P + ++    P P A   + +  PA  P S    PA       
Sbjct: 1343 PKGTPTLPATTPSSKGGPTTPSSKEG-PTPPAATPSHKGGPAMTPPSPKRGPA------- 1394

Query: 441  WLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALP--PCARECQSLPQKEDARPPSSP 498
             +PS + +   P +              +P +P   P  P  RE  + P K D  PP+  
Sbjct: 1395 -IPSPKGDPTSPAV--------------IPLSPKKAPATPVTREGAATPSKGDLTPPAVT 1439

Query: 499  PMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGP 558
            P+ +     + AP        +    T P      P   PA  +          PA   P
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499

Query: 559  SGSKPLRG----SLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSD 614
             G+  L      S KE  A   S R P A  + + + ++     P  A+  P +      
Sbjct: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAM-----T 1554

Query: 615  LPGLKKIDT-----EAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKIL--------RPAP 661
            +P  KK        EAP  P     +     T      A   ++  I         + AP
Sbjct: 1555 VPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAP 1614

Query: 662  LPAAVVPSTPTSAPAPTQPAPTPTSGPI---GLRILAQQPLSVTC--------FSLALPS 710
             P AV P +P   PA   P  TPTS P+    L+     P SVTC         S  LP+
Sbjct: 1615 TPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPA 1674

Query: 711  ---PPAVAVASPAPAPAPSP---APAR---AQAPASARDPAPAPAPVA---GPAPASTSA 758
               P A+     APAP  +P   AP R       +SA  P   P P A      P ST A
Sbjct: 1675 KKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVA 1734

Query: 759  PGDSL 763
            P   L
Sbjct: 1735 PAPLL 1739



 Score =  100 bits (249), Expect = 7e-21
 Identities = 150/638 (23%), Positives = 212/638 (33%), Gaps = 97/638 (15%)

Query: 160  TLATGPLLPSADPPCSLAPAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQT 219
            TL T PL+P+A   C +AP+P        T +       S    S   +   P  +K   
Sbjct: 694  TLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDG 753

Query: 220  IHSTGFLASRYTGPYPRNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHP 279
            I  T  LA     P   + K+  +E   +  T  ++       D+            P P
Sbjct: 754  ISHTSALA-----PVASSPKECPTEDSGASATASSKGTLTYLADS------------PSP 796

Query: 280  PQALPCPPACRHPEKQGSYSPALPL----QPLGGHKGTGYQAGGLGSPYLRQQAAQAPYI 335
                  P   R P K+GS  P  P+     P+   + +      L     +   A     
Sbjct: 797  LGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSP 856

Query: 336  PPLGLDAYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYG--ASPG 393
             P      P PSA  P    G+ L P  TP       P  ++ P+ ++  +      +P 
Sbjct: 857  TPPSPKGAPTPSAVTPLSPKGVTLPPKETP------TPSVVNLPFPKEGPATPAPKQAPA 910

Query: 394  LGGTPPSQNNVRAVPQPGAFQRACQPL-----PASQPCSEPVRPAQEAEEKTWLPSCRKE 448
            L  T  S    RA P P     +  P      PA+ P S    PA  + +  W P+    
Sbjct: 911  LSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK--WAPT---- 964

Query: 449  KLQPRLSEHS--GPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNV 506
               P  +  S  G P        P  P A PP  +   + P  + A  P +   P     
Sbjct: 965  --PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP----- 1017

Query: 507  FSLAPYRDYLDVPAPEATTEPDSAT-AEPDSAPATS---EGQDKGCRGTLPAQEGPSGSK 562
               +P       P P+  + P +AT   P  +PA +   +G       TLP+ +G   + 
Sbjct: 1018 ---SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATP 1074

Query: 563  PLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKID 622
             L+G+     A       P+ +  P   S       P A    P  G       G     
Sbjct: 1075 SLKGAPTPPAA-----TPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTP 1129

Query: 623  TEAPGLP----------GVPVTTDAMPRTNFHSSVAFMFRKFKILRPAP-----LPAAVV 667
               P  P          G P T  A P +           K  +  P P      PAA  
Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATPPS----------PKGGLATPPPKGAPTTPAATP 1179

Query: 668  PS------TPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAP 721
            PS      TP+   APT PA TP S   GL      P        A P  P   +A+P+P
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGL--ATPSPKGAPTTPAATPPSPKGGLATPSP 1237

Query: 722  APAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAP 759
              AP+     A  P S +     P P   P P + + P
Sbjct: 1238 KGAPT---TPAATPPSPKGGPATPPPKGAPTPPAATPP 1272



 Score = 87.0 bits (214), Expect = 8e-17
 Identities = 187/791 (23%), Positives = 280/791 (35%), Gaps = 129/791 (16%)

Query: 51   PMAGTPKAESEQLASWTPYPPLYSTGMAGPPLQADNLLTNCLFYRSPAEGPEKMQDSSPV 110
            P A TP +    LA+  P+    +T  A PP     L T           P K   ++P 
Sbjct: 1105 PPAATPPSPKGGLAT-PPHKGAPTTPAATPPSPKGGLATP----------PPKGAPTTPA 1153

Query: 111  ELLPFSPQAHSYPGPPLAAPKPVYRNPLCY--GLSTCLGEGAVKRPLDVDWTLATGPLLP 168
               P SP+      PP  AP      P     GL+T   +GA   P     +   G   P
Sbjct: 1154 ATPP-SPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212

Query: 169  SAD----PPCSLAPAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHST- 223
            S       P +  P+P  G        +G P   ++   S    P  P  +   T  +  
Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPSP--KGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT 1270

Query: 224  -----GFLASRYTGPYPRNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPH 278
                 G LA   T P+      A+   PS        P  P    T P   PP     P 
Sbjct: 1271 PPSLKGGLA---TPPHKGAPNPAVVTPPSPKGGPATSP--PKGAPTPPAATPPSPKGSPG 1325

Query: 279  --PPQALPCPPACRHPEKQGSYS-PALPLQPLGGHKGTGYQAGGL---------GSPYLR 326
              PP+  P PPA   P  +G+ + PA      GG      + G           G P + 
Sbjct: 1326 TPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385

Query: 327  QQAAQ-APYIP-PLGLDAYP--YPSAPLPAPSPGLKLE-----------PPLTPRCPLDF 371
              + +  P IP P G    P   P +P  AP+  +  E           PP      L  
Sbjct: 1386 PPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445

Query: 372  APQTLS------FPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQP 425
            AP T +       P ++ D +L   +P     PP+   V     P   +    P P   P
Sbjct: 1446 APATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK--KAPATPAPMGAP 1503

Query: 426  CSEPVRPAQEAEEKTWLPSCRKEKLQPR---LSEHSGPPIVIRDSPVPCTPPALPPCARE 482
                V P+   E     PS R++ + P    LS+ +   +  +++ +P  P    P  ++
Sbjct: 1504 TLPAVIPSSPKEVPA-TPSSRRDPIAPTATLLSKKTPATLAPKEALIP--PAMTVPSPKK 1560

Query: 483  CQSLPQKEDA------RPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDS 536
              ++P  ++A      +  SSPP  V  + +  AP    L +P    +  P  A   P  
Sbjct: 1561 TPAIPTPKEAPATPSSKEASSPPA-VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAV 1619

Query: 537  APATSEGQDKGCRGTLPAQEGPSGSKPLR-GSLKEEVALDLSVRKPTAEASPVKASRSVE 595
             P + E   KG     PA +G   S P+   SLK+      SV        P +AS+ + 
Sbjct: 1620 TPPSPE---KG--PATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVP-QASKGLP 1673

Query: 596  HAK-PTAAMDV-----PDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAF 649
              K PTA  +V     P+   +++  P  K   T+       P+  D   +      ++ 
Sbjct: 1674 AKKGPTALKEVLVAPAPESTPIIT-APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLS- 1731

Query: 650  MFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALP 709
                   + PAPL      S+ T+       +P     P   +  A  PL+   F   LP
Sbjct: 1732 ------TVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESK--ASTPLTAAAFEKVLP 1783

Query: 710  SPPAVAV-ASPAP------APAPSP------------------APARAQAPASARD--PA 742
             P + +V A+P+P      AP+P P                  +P++  APA   +  P 
Sbjct: 1784 KPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPL 1843

Query: 743  PAPAPVAGPAP 753
              P P++G  P
Sbjct: 1844 IPPEPISGGVP 1854



 Score = 78.2 bits (191), Expect = 4e-14
 Identities = 172/732 (23%), Positives = 247/732 (33%), Gaps = 140/732 (19%)

Query: 53   AGTPKAESEQLASWTPYPP-LYSTGMAGPPLQADNLLTNCLFYRSPAEGPEKMQDSSPVE 111
            A TP +    LA  TP P    +T  A PP     L T      SP   P     + P  
Sbjct: 1199 AATPPSPKGGLA--TPSPKGAPTTPAATPPSPKGGLATP-----SPKGAPTTPAATPP-- 1249

Query: 112  LLPFSPQAHSYPGPPLAAPKPVYRNP--LCYGLSTCLGEGA----VKRPLDVDWTLATGP 165
                SP+      PP  AP P    P  L  GL+T   +GA    V  P       AT P
Sbjct: 1250 ----SPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP 1305

Query: 166  LLPSADPPCSLAPAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHSTGF 225
               +  PP +  P+P           +G P     K +    +   P  +   T+ +T  
Sbjct: 1306 PKGAPTPPAATPPSP-----------KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPAT-- 1352

Query: 226  LASRYTGPYPRNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHP------ 279
              S   GP   +SK+  +   ++P  +    + PP    GP   P P   P  P      
Sbjct: 1353 TPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPA-IPSPKGDPTSPAVIPLS 1411

Query: 280  PQALPCPPACRH----PEKQGSYSPALPLQPLGGHKGTGYQAGG------LGSPYLRQQA 329
            P+  P  P  R     P K     PA+    L     T    GG       G P L    
Sbjct: 1412 PKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471

Query: 330  AQAPYIPP----LGLDAYPY--PSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARD 383
              +P  PP    +   + P   P+ P P  +P L    P +P+  +   P +   P A  
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPK-EVPATPSSRRDPIAPT 1530

Query: 384  DLSLYGASPGL----------GGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPA 433
               L   +P              T PS     A+P P    +     P+S+  S P  PA
Sbjct: 1531 ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTP----KEAPATPSSKEASSP--PA 1584

Query: 434  QEAEEKTWLPSCRKEKLQPRLSEHSG-----PPIVIRDSP-----------VPCTPPALP 477
                     PS ++  + P ++  S      PP V   SP            P +PP  P
Sbjct: 1585 VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTP 1644

Query: 478  PCARECQSLPQKEDAR-----PPSSPPMPVIDNVFSLAPYRDYLDVPAPEAT-------- 524
               ++  + P     +     P +S  +P      +L   ++ L  PAPE+T        
Sbjct: 1645 SSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTAL---KEVLVAPAPESTPIITAPTR 1701

Query: 525  ----TEPDSATAEPDSAPATSEGQDKGCRGT------LPAQE-------GPSGSKPLRGS 567
                T+  SAT+ P     +++   KG   T      LP Q+       G   S   +G 
Sbjct: 1702 KGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGP 1761

Query: 568  L-----KEEVALDLSVRK---PTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLK 619
            L     K    L  +  +   P  E++ V A+ S   + P A   VP +      LP   
Sbjct: 1762 LAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSP 1821

Query: 620  KIDTEAPGLPGVPVTTDAM----PRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAP 675
             +  E+P  P  P   D +    P       V   F+   +  P P  A +    P   P
Sbjct: 1822 GLVLESPSKPLAPADEDELLPLIPPEPISGGVP--FQSVLVNMPTPKSAGI----PVPTP 1875

Query: 676  APTQPAPTPTSG 687
            +  QP      G
Sbjct: 1876 SAKQPVTKNNKG 1887



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 118/502 (23%), Positives = 161/502 (32%), Gaps = 64/502 (12%)

Query: 297  SYSPALPLQP--------LGGHKGTGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSA 348
            S SP +PL P        LG     G  A  + SP     +A       +  D+Y  P +
Sbjct: 577  SSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASV-----IKTDSYAGPDS 631

Query: 349  PLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYG--ASPGLGGT--------P 398
              P     L    P     PL+ A      P      S Y   ASP L GT        P
Sbjct: 632  AGPLLKSSLIT--PTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHP 689

Query: 399  PSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHS 458
              +  +  +P        C   P+ Q    P+     A      P   K    P L    
Sbjct: 690  VKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLA------PEIPKSVPSPSLPPAG 743

Query: 459  GPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDV 518
             PP   +   +  T  AL P A   +  P ++     ++     +     LA     L V
Sbjct: 744  TPPGTKKVDGISHTS-ALAPVASSPKECPTEDSGASATASSKGTLTY---LADSPSPLGV 799

Query: 519  PAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSV 578
                 T  P   T +  + P T  G        + A   P  S   +GS K+  A   S 
Sbjct: 800  SVSPQTKRPP--TKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGS-KDSPATTHSP 856

Query: 579  RKPTAEASPVKASRSVEHAK----PTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVT 634
              P+ + +P  ++ +    K    P      P V N+     G     T AP        
Sbjct: 857  TPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPA---TPAPKQAPALSM 913

Query: 635  TDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPA-------PTQPAPTPTSG 687
            T + P+    +            + AP P A  P +P   PA       PT PA TP S 
Sbjct: 914  TSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSP 973

Query: 688  PIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSP----------APARAQAPAS 737
              G       P        A P  P    A+P+P  AP+P          +PA    P  
Sbjct: 974  KGGPA--TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKG 1031

Query: 738  ARDPAPAPAPVAGPAPASTSAP 759
            A  P  A  P    +PA+T  P
Sbjct: 1032 ASTPPAATPPSPKGSPAATPLP 1053



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 117/522 (22%), Positives = 171/522 (32%), Gaps = 68/522 (13%)

Query: 256 PLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGY 315
           P+      T     P P  PPP  P    CP +  +          +   PL       +
Sbjct: 27  PMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPL----EVPF 82

Query: 316 QAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQT 375
                G+      A +AP   P  L   P   A L   SP +      TP      A   
Sbjct: 83  PQSSSGTALPLGTAPEAPTFLP-NLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVA 141

Query: 376 LSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQE 435
           L+ P++    S +   P L  +PPS     AV + G+      P+  S+P          
Sbjct: 142 LA-PHSVQKSSAF--PPNLLTSPPSV----AVAESGSVITLSAPIAPSEP---------- 184

Query: 436 AEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPP 495
              KT L     E + P       PP ++   P  C  P +        SLPQ       
Sbjct: 185 ---KTNLNKVPSE-VVPNPKGTPSPPCIVSTVPYHCVTP-MASIQSGVASLPQTTPTTTL 239

Query: 496 SSPPMPVIDNVFS---LAPYR-DYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGT 551
           +     V D   S   ++P     L +  P   + P + +    S P  +  Q      T
Sbjct: 240 AIASPQVKDTTISSVLISPQNPGSLSLKGP--VSPPAALSLSTQSLPVVTSSQKTAGPNT 297

Query: 552 LPAQEGPSGS--KPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVG 609
            P      GS   PL  S    V L L    P+A + P   + SV+H+   A+   P   
Sbjct: 298 PPDFPISLGSHLAPLHQSSFGSVQL-LGQTGPSALSDPTVKTISVDHSSTGAS--YPSQR 354

Query: 610 NMVSDLPGLKK-IDTEAPGLPGVPVTTDAMPRT------------NFHSSVAFMFRKFKI 656
           +++  LP   + +       P V  + D  P T            N  +S +       I
Sbjct: 355 SVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLI 414

Query: 657 LRPAP-----------LPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFS 705
           L+ +P           +P + V +TP     P   A  PT+    +      P+S    S
Sbjct: 415 LKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTT-TFEVATCVSPPMSSGPIS 473

Query: 706 LALPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAP 747
              P+ PA  V +P     PS      Q   + R P   P P
Sbjct: 474 NIEPTSPAALVMAPVAPKEPS-----TQVATTLRIPVSPPLP 510



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 5/67 (7%)

Query: 940  PTVARDE--PESLALAQKSPAPKVRKPGRKPPT---PGPEKAEAAAGEESCGASPTPATS 994
            P+  RD   P +  L++K+PA    K    PP    P P+K  A    +   A+P+   +
Sbjct: 1520 PSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEA 1579

Query: 995  ASPPGPT 1001
            +SPP  T
Sbjct: 1580 SSPPAVT 1586



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 1/46 (2%)

Query: 956  SPAPKVRKPGRKPPTPGPEKAEAAAGEESCGASPTPATSASPPGPT 1001
            +PAPK + P     +  P+KA A    +   ASP+P  + +PP  T
Sbjct: 902  TPAPK-QAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAAT 946



 Score = 30.4 bits (67), Expect = 9.1
 Identities = 28/90 (31%), Positives = 37/90 (41%), Gaps = 15/90 (16%)

Query: 673 SAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARA 732
           + PA  Q  P P +    L +     LSVT  +L  P P      SPAP   P  A    
Sbjct: 8   TVPATEQELPQPQAETAVLPM--SSALSVTA-ALGQPGPTLPPPCSPAPQQCPLSA---- 60

Query: 733 QAPASARDPAPAPAPVAG-----PAPASTS 757
              A+   P P+P+ +A      P P S+S
Sbjct: 61  ---ANQASPFPSPSTIASTPLEVPFPQSSS 87


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score = 90.9 bits (224), Expect = 6e-18
 Identities = 164/629 (26%), Positives = 207/629 (32%), Gaps = 98/629 (15%)

Query: 181  SKGQTLDGTFLRGVPAEGS--SKDSSGSFSPCQPFLE-KYQTIHSTGFLASRYTGPYPRN 237
            S      G+    +P   S  S  S    S  QP    + Q+I S+ F  +   G     
Sbjct: 530  SSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEE 589

Query: 238  SKQAMSEGPSSPWTQLAQPLGP---------PCQDTGPTHYPPPHHPPPHPPQALPCPP- 287
            S +A  E  + P+T L  PL P           Q + P   PPP  PPP PP   P PP 
Sbjct: 590  SSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPL 649

Query: 288  ACRHPEKQGS-------YSPALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQAPYI--PPL 338
              +     GS       YS    LQ    H G  ++     +P + Q  +  P I  PP 
Sbjct: 650  PSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKP---PTPPVMQSQSVKPQILVPPN 706

Query: 339  GLDAYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTP 398
            G+   P P  P P P+PG      +    P   AP    F      L ++         P
Sbjct: 707  GV--VPPPPPPPPPPTPG----SAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAP 760

Query: 399  PSQNNVRAVPQPGAFQRACQPL-----PASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPR 453
            P+      +P P   Q   +PL     P S     PV    +A   T  P     K QP 
Sbjct: 761  PTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPV--VTQAAPPTPTPPVPPAKKQPA 818

Query: 454  LSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYR 513
                  PP      PVP  PP LP     C        A+PP SP  PV   V  +A   
Sbjct: 819  FPASYIPPSP-PTPPVPVPPPTLPKQQSFC--------AKPPPSPLSPVPSVVKQIA--S 867

Query: 514  DYLDVPAPEA----TTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLK 569
             +   P P A      +P  A   P S PA  + + K    ++P         P   SL 
Sbjct: 868  QFPPPPTPPAMESQPLKPVPANVAPQSPPAV-KAKPKWQPSSIPVPSPDFPPPPPESSLV 926

Query: 570  EEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLP 629
                       P    SPV A        P  A   PD     S  PG K   T +PG  
Sbjct: 927  ----------FPPPPPSPVPAP---PPPPPPTASPTPD----KSGSPGKKTSKTSSPGGK 969

Query: 630  GVPVTTDAMPRTNFHS----------SVAFMFRKFKILRPAPLPAAVVPSTPTSAP--AP 677
              P T          S          SV  +  KF      P   +  PS  T  P  AP
Sbjct: 970  KPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKF-----TPPAESGSPSKETLPPPAAP 1024

Query: 678  TQPAPTPTSGPIGLRILAQQPLSVTCFSLA---------LPSPPAVAVASPAPAPAPSPA 728
             +P     SG     +L Q  +S     L+          PSPP+ +   P P     P 
Sbjct: 1025 PKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPL 1084

Query: 729  PARAQAPASARDPAPAPAPVAGPAPASTS 757
            P   + PA           V  P P   S
Sbjct: 1085 PP-IEIPAVFSGNTSPKVAVVNPQPQQWS 1112



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 107/423 (25%), Positives = 143/423 (33%), Gaps = 85/423 (20%)

Query: 355 PGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQ 414
           P   L PPL+P+ P    P T S P           SP L   PP        P P    
Sbjct: 601 PYTSLVPPLSPQ-PKIVTPYTASQP-----------SPPLPPPPP--------PPP---- 636

Query: 415 RACQPLPASQPCSEPVRPAQEAEEK-TWLPSCRKEKLQPRL---SEHSGPPIVIRDSPVP 470
               P P   P   P  P+Q A    +  P   K     RL   S+HSG          P
Sbjct: 637 ----PPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFK------P 686

Query: 471 CTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSA 530
            TPP +   + + Q L       PP  PP P      ++A  +     PAP A + P   
Sbjct: 687 PTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLK-----PAPCAPSLPQF- 740

Query: 531 TAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKA 590
                SAP       +    T  A   P    P+   L  +      V  P   ++   A
Sbjct: 741 -----SAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVA 795

Query: 591 SRSVEHAKPTAAMDVPDVGNM----VSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSS 646
               + A PT    VP          S +P        +P  P VPV    +P+     +
Sbjct: 796 PVVTQAAPPTPTPPVPPAKKQPAFPASYIP-------PSPPTPPVPVPPPTLPKQQSFCA 848

Query: 647 VAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSL 706
                      +P P P + VPS      +   P PTP +       +  QPL     ++
Sbjct: 849 -----------KPPPSPLSPVPSVVKQIASQFPPPPTPPA-------MESQPLKPVPANV 890

Query: 707 ALPSPPAVAV-------ASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAP 759
           A  SPPAV         + P P+P   P P  +        P+P PAP   P P ++  P
Sbjct: 891 APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTP 950

Query: 760 GDS 762
             S
Sbjct: 951 DKS 953


>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 90.1 bits (222), Expect = 1e-17
 Identities = 50/107 (46%), Positives = 58/107 (54%), Gaps = 20/107 (18%)

Query: 659 PAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVAS 718
           P P PA+  P  P  APAP  PAP P + P+                    +P AVAV +
Sbjct: 129 PVPAPASTPPPVPVLAPAPA-PAPAPVAAPVA-------------------APVAVAVLA 168

Query: 719 PAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQ 765
           PAPAPAP+PAPA A   A A  PAPAPAP   PAPA  +AP +S EQ
Sbjct: 169 PAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQ 215



 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 52/149 (34%), Positives = 67/149 (44%), Gaps = 31/149 (20%)

Query: 626 PG-LPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTP 684
           PG L    V +D++P   F+     + R   +L P P+  AV  S P       +PA   
Sbjct: 63  PGRLQWTEVDSDSVPA--FYRETVQVGRCRLLLAPRPVAVAVAVSPPL------EPAAES 114

Query: 685 TSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPA-------------- 730
             G      L + P  +   S+ +P+P +     P  APAP+PAPA              
Sbjct: 115 LDG------LEEAPEQLP--SVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAV 166

Query: 731 RAQAPASARDPAPAPAPVAGPAPASTSAP 759
            A APA A  PAPAPAPVA PAPA   AP
Sbjct: 167 LAPAPAPAPAPAPAPAPVAAPAPAPAPAP 195



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 54/219 (24%), Positives = 86/219 (39%), Gaps = 20/219 (9%)

Query: 408 PQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDS 467
           P+P A   A  P    +P +E +   +EA E+  LPS       P  +    P  V+  +
Sbjct: 95  PRPVAVAVAVSP--PLEPAAESLDGLEEAPEQ--LPSVPV----PAPASTPPPVPVLAPA 146

Query: 468 PVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEP 527
           P P   P   P A    ++     A  P+  P P    V + AP       PAP     P
Sbjct: 147 PAPAPAPVAAPVAAPV-AVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAP 205

Query: 528 DSATAEPDSAPATSEGQDKGCRGTLPAQE----GPSGSKPLRGSLKEEVALDLSVRKPTA 583
           D+A  E     +  +G ++G RG  P  +    G SG +P  G+     A   +++K + 
Sbjct: 206 DAAPQE-----SAEQGANQGQRGQEPLADQLHSGISG-RPAAGTAAAS-ANGAAIKKLSG 258

Query: 584 EASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKID 622
                  ++    A   ++ DVP      S  PG+  ++
Sbjct: 259 PLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVE 297



 Score = 35.4 bits (80), Expect = 0.28
 Identities = 44/185 (23%), Positives = 62/185 (33%), Gaps = 20/185 (10%)

Query: 325 LRQQAAQAPYIPPLGLDAYPYPS---APLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYA 381
           L +   Q P +P     + P P    AP PAP+P     P   P      AP     P  
Sbjct: 118 LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAP 177

Query: 382 RDDLSLYGA-----SPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPV------ 430
               +   A     +P     P       A PQ  A Q A Q     +P ++ +      
Sbjct: 178 APAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISG 237

Query: 431 RPAQEAEEKTWLPSCRKEKLQPRLSE------HSGPPIVIRDSPVPCTPPALPPCARECQ 484
           RPA      +   +  K+   P +S+       S P     D P PC  P+  P     +
Sbjct: 238 RPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVE 297

Query: 485 SLPQK 489
             P+K
Sbjct: 298 QTPRK 302



 Score = 34.3 bits (77), Expect = 0.63
 Identities = 38/124 (30%), Positives = 49/124 (39%), Gaps = 23/124 (18%)

Query: 656 ILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGP---------IGLRILAQQPLSVTCFSL 706
           +  PAP PA      P  APAP  PAP P + P          G R   Q+PL+    S 
Sbjct: 184 VAAPAPAPA------PAPAPAPA-PAPAPDAAPQESAEQGANQGQR--GQEPLADQLHSG 234

Query: 707 ALPSPPAVAVASPAPAPA----PSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPG-D 761
               P A   A+ A   A      P  +   A      P  +   V  P P+ ++APG  
Sbjct: 235 ISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVG 294

Query: 762 SLEQ 765
           S+EQ
Sbjct: 295 SVEQ 298


>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 90.1 bits (222), Expect = 1e-17
 Identities = 50/107 (46%), Positives = 58/107 (54%), Gaps = 20/107 (18%)

Query: 659 PAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVAS 718
           P P PA+  P  P  APAP  PAP P + P+                    +P AVAV +
Sbjct: 129 PVPAPASTPPPVPVLAPAPA-PAPAPVAAPVA-------------------APVAVAVLA 168

Query: 719 PAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQ 765
           PAPAPAP+PAPA A   A A  PAPAPAP   PAPA  +AP +S EQ
Sbjct: 169 PAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQ 215



 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 52/149 (34%), Positives = 67/149 (44%), Gaps = 31/149 (20%)

Query: 626 PG-LPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTP 684
           PG L    V +D++P   F+     + R   +L P P+  AV  S P       +PA   
Sbjct: 63  PGRLQWTEVDSDSVPA--FYRETVQVGRCRLLLAPRPVAVAVAVSPPL------EPAAES 114

Query: 685 TSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPA-------------- 730
             G      L + P  +   S+ +P+P +     P  APAP+PAPA              
Sbjct: 115 LDG------LEEAPEQLP--SVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAV 166

Query: 731 RAQAPASARDPAPAPAPVAGPAPASTSAP 759
            A APA A  PAPAPAPVA PAPA   AP
Sbjct: 167 LAPAPAPAPAPAPAPAPVAAPAPAPAPAP 195



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 54/219 (24%), Positives = 86/219 (39%), Gaps = 20/219 (9%)

Query: 408 PQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDS 467
           P+P A   A  P    +P +E +   +EA E+  LPS       P  +    P  V+  +
Sbjct: 95  PRPVAVAVAVSP--PLEPAAESLDGLEEAPEQ--LPSVPV----PAPASTPPPVPVLAPA 146

Query: 468 PVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEP 527
           P P   P   P A    ++     A  P+  P P    V + AP       PAP     P
Sbjct: 147 PAPAPAPVAAPVAAPV-AVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAP 205

Query: 528 DSATAEPDSAPATSEGQDKGCRGTLPAQE----GPSGSKPLRGSLKEEVALDLSVRKPTA 583
           D+A  E     +  +G ++G RG  P  +    G SG +P  G+     A   +++K + 
Sbjct: 206 DAAPQE-----SAEQGANQGQRGQEPLADQLHSGISG-RPAAGTAAAS-ANGAAIKKLSG 258

Query: 584 EASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKID 622
                  ++    A   ++ DVP      S  PG+  ++
Sbjct: 259 PLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVE 297



 Score = 35.4 bits (80), Expect = 0.28
 Identities = 44/185 (23%), Positives = 62/185 (33%), Gaps = 20/185 (10%)

Query: 325 LRQQAAQAPYIPPLGLDAYPYPS---APLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYA 381
           L +   Q P +P     + P P    AP PAP+P     P   P      AP     P  
Sbjct: 118 LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAP 177

Query: 382 RDDLSLYGA-----SPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPV------ 430
               +   A     +P     P       A PQ  A Q A Q     +P ++ +      
Sbjct: 178 APAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISG 237

Query: 431 RPAQEAEEKTWLPSCRKEKLQPRLSE------HSGPPIVIRDSPVPCTPPALPPCARECQ 484
           RPA      +   +  K+   P +S+       S P     D P PC  P+  P     +
Sbjct: 238 RPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVE 297

Query: 485 SLPQK 489
             P+K
Sbjct: 298 QTPRK 302



 Score = 34.3 bits (77), Expect = 0.63
 Identities = 38/124 (30%), Positives = 49/124 (39%), Gaps = 23/124 (18%)

Query: 656 ILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGP---------IGLRILAQQPLSVTCFSL 706
           +  PAP PA      P  APAP  PAP P + P          G R   Q+PL+    S 
Sbjct: 184 VAAPAPAPA------PAPAPAPA-PAPAPDAAPQESAEQGANQGQR--GQEPLADQLHSG 234

Query: 707 ALPSPPAVAVASPAPAPA----PSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPG-D 761
               P A   A+ A   A      P  +   A      P  +   V  P P+ ++APG  
Sbjct: 235 ISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVG 294

Query: 762 SLEQ 765
           S+EQ
Sbjct: 295 SVEQ 298


>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
           sapiens]
          Length = 316

 Score = 90.1 bits (222), Expect = 1e-17
 Identities = 50/107 (46%), Positives = 58/107 (54%), Gaps = 20/107 (18%)

Query: 659 PAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVAS 718
           P P PA+  P  P  APAP  PAP P + P+                    +P AVAV +
Sbjct: 140 PVPAPASTPPPVPVLAPAPA-PAPAPVAAPVA-------------------APVAVAVLA 179

Query: 719 PAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQ 765
           PAPAPAP+PAPA A   A A  PAPAPAP   PAPA  +AP +S EQ
Sbjct: 180 PAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQ 226



 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 52/149 (34%), Positives = 67/149 (44%), Gaps = 31/149 (20%)

Query: 626 PG-LPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTP 684
           PG L    V +D++P   F+     + R   +L P P+  AV  S P       +PA   
Sbjct: 74  PGRLQWTEVDSDSVPA--FYRETVQVGRCRLLLAPRPVAVAVAVSPPL------EPAAES 125

Query: 685 TSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPA-------------- 730
             G      L + P  +   S+ +P+P +     P  APAP+PAPA              
Sbjct: 126 LDG------LEEAPEQLP--SVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAV 177

Query: 731 RAQAPASARDPAPAPAPVAGPAPASTSAP 759
            A APA A  PAPAPAPVA PAPA   AP
Sbjct: 178 LAPAPAPAPAPAPAPAPVAAPAPAPAPAP 206



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 54/219 (24%), Positives = 86/219 (39%), Gaps = 20/219 (9%)

Query: 408 PQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDS 467
           P+P A   A  P    +P +E +   +EA E+  LPS       P  +    P  V+  +
Sbjct: 106 PRPVAVAVAVSP--PLEPAAESLDGLEEAPEQ--LPSVPV----PAPASTPPPVPVLAPA 157

Query: 468 PVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEP 527
           P P   P   P A    ++     A  P+  P P    V + AP       PAP     P
Sbjct: 158 PAPAPAPVAAPVAAPV-AVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAP 216

Query: 528 DSATAEPDSAPATSEGQDKGCRGTLPAQE----GPSGSKPLRGSLKEEVALDLSVRKPTA 583
           D+A  E     +  +G ++G RG  P  +    G SG +P  G+     A   +++K + 
Sbjct: 217 DAAPQE-----SAEQGANQGQRGQEPLADQLHSGISG-RPAAGTAAAS-ANGAAIKKLSG 269

Query: 584 EASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKID 622
                  ++    A   ++ DVP      S  PG+  ++
Sbjct: 270 PLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVE 308



 Score = 35.4 bits (80), Expect = 0.28
 Identities = 44/185 (23%), Positives = 62/185 (33%), Gaps = 20/185 (10%)

Query: 325 LRQQAAQAPYIPPLGLDAYPYPS---APLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYA 381
           L +   Q P +P     + P P    AP PAP+P     P   P      AP     P  
Sbjct: 129 LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAP 188

Query: 382 RDDLSLYGA-----SPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPV------ 430
               +   A     +P     P       A PQ  A Q A Q     +P ++ +      
Sbjct: 189 APAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISG 248

Query: 431 RPAQEAEEKTWLPSCRKEKLQPRLSE------HSGPPIVIRDSPVPCTPPALPPCARECQ 484
           RPA      +   +  K+   P +S+       S P     D P PC  P+  P     +
Sbjct: 249 RPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVE 308

Query: 485 SLPQK 489
             P+K
Sbjct: 309 QTPRK 313



 Score = 34.3 bits (77), Expect = 0.63
 Identities = 38/124 (30%), Positives = 49/124 (39%), Gaps = 23/124 (18%)

Query: 656 ILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGP---------IGLRILAQQPLSVTCFSL 706
           +  PAP PA      P  APAP  PAP P + P          G R   Q+PL+    S 
Sbjct: 195 VAAPAPAPA------PAPAPAPA-PAPAPDAAPQESAEQGANQGQR--GQEPLADQLHSG 245

Query: 707 ALPSPPAVAVASPAPAPA----PSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPG-D 761
               P A   A+ A   A      P  +   A      P  +   V  P P+ ++APG  
Sbjct: 246 ISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVG 305

Query: 762 SLEQ 765
           S+EQ
Sbjct: 306 SVEQ 309


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 183/756 (24%), Positives = 249/756 (32%), Gaps = 153/756 (20%)

Query: 70  PPLYSTGMAGPPLQADNLLTNCLFYRSPAEGPEKMQDSSPVELLPFSPQAHSYPGPPLAA 129
           PP      A  PL +  L T       P+    K +   P +       A   P PPLA 
Sbjct: 287 PPRKDAAPALGPLSSSPLAT-------PSPSGTKARPVPPPDNAATPLPATLPPSPPLAT 339

Query: 130 PKPVYR-NPLCYGLSTCLGEGAVKRPLDVDWTLATGPLLPSADPPCSLAPAPSKGQTLDG 188
           P P+   +P        L       P     ++ T P+   A P     P      +L  
Sbjct: 340 PLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM--QAPPSLQTIPPIQVPHSLTS 397

Query: 189 TFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYPRNSKQAMSEGPSS 248
             L+  P+  +      + S   P L   Q  HS   ++ R T     +  +  S  P S
Sbjct: 398 PSLQAPPSPLALSSLQATTSLGSPTL---QATHSFLTMSPRQTQASLTSPSRPASTPPDS 454

Query: 249 PWTQ--LAQPLGPPCQDTGPTHYPPPHHPPP-HPPQALPCPPACRHPEKQGSYSPALPLQ 305
           P  Q  L+ P  PP Q +      P   P   HP QAL             S+SP  PL 
Sbjct: 455 PPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL---------SSLASHSPQAPLS 505

Query: 306 PLGGHKGTGYQAGGLGSPYLRQQAAQAP---YIPPLGLDAYPYPSAPLPAPSPGLKLEPP 362
                         L  P L  Q++ AP     PP  L   P  + P  AP P      P
Sbjct: 506 -------------SLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAP 552

Query: 363 LTPR----------CPLDFAPQTLSFPYARDDLSLYG---------ASPGLGGTPPSQNN 403
           LT            CPL   P  L+ P      S+           ASP L G P    +
Sbjct: 553 LTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLS 612

Query: 404 VRAVPQPGAFQRACQP---LPASQPCSEPVRPAQEAEEKTWLPSCRK-EKLQPRLSEHSG 459
             A P P A      P    P S P S P+ P   A      P+      LQ   S    
Sbjct: 613 PLATPPPQAPPXLALPPLQAPPSPPASPPLSPL--ATPSPQAPNALAVHLLQAPFSPPPS 670

Query: 460 PPIVIRDSPVPCTPPALPPCARECQSLPQ------KEDARPPSSPPMPVIDNVFSLAPYR 513
           PP+    SP P +PP  P      Q+ P       +    PP+SPPM    +  +  P +
Sbjct: 671 PPVQAPFSP-PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM----SPSATPPPQ 725

Query: 514 DYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVA 573
               + AP     P    + P S  AT   +        P Q  PS    L  S      
Sbjct: 726 APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMS------ 779

Query: 574 LDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPG--V 631
               + KP  +A P  A+       P  A+  P      +  PG      +AP  P   +
Sbjct: 780 ---PLAKPPPQAPPALAT------PPLQALPSPP-----ASFPG------QAPFSPSASL 819

Query: 632 PVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGL 691
           P++  A P       +A              P   VP +P ++P    P   PT GP   
Sbjct: 820 PMSPLATPPPQAPPVLA-------------APLLQVPPSPPASPTLQAPRRPPTPGP--- 863

Query: 692 RILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGP 751
                          ++  P      +P P P PS +P+   +  S  D       +AG 
Sbjct: 864 -------------DTSVSGPRLTLALAPGPPPPPSRSPS---STLSGPD-------LAGH 900

Query: 752 APASTSAPGDSLEQHFTGLHASLCDAISGSVAHSPP 787
           + ++TS P + L  + +G          G  A SPP
Sbjct: 901 SSSATSTP-EELRGYDSG--------PEGGAAASPP 927



 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 195/771 (25%), Positives = 253/771 (32%), Gaps = 202/771 (26%)

Query: 68   PYPPLYSTGMAGPPLQADNLLTNCLFYRSPAEGPEKMQDSSPVELLPFSPQAHSYPGPPL 127
            P PP      A PP QA   +T       P + P  +Q   P+++       HS   P L
Sbjct: 358  PSPP------ATPPSQAPPSMTT-----PPMQAPPSLQTIPPIQV------PHSLTSPSL 400

Query: 128  AAPKPVYRNPLCYG---LSTCLGEGAVKR--------PLDVDWTLATGPLLPSADPPCSL 176
             AP     +PL       +T LG   ++         P     +L T P  P++ PP   
Sbjct: 401  QAPP----SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASL-TSPSRPASTPP--- 452

Query: 177  APAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYPR 236
                      D   L+   +  +S     S SP    L    TIH    L+S  +     
Sbjct: 453  ----------DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLAS----- 497

Query: 237  NSKQAMSEGPSSPWTQLAQPLGPPCQDTGPT----------------------------H 268
            +S QA       P  +    L PP   T P                             H
Sbjct: 498  HSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPH 557

Query: 269  YPPPHHPPPHPPQALPCPPACRHPEKQGSYS-------PALPLQPLGGHKGTGYQAGGLG 321
               P  P P P QA P P     PE   S +       PAL   PL G          L 
Sbjct: 558  LETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG----------LP 607

Query: 322  SPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYA 381
            SP L   A   P  PP  L   P  + P P  SP L      +P+ P   A   L  P++
Sbjct: 608  SPPLSPLATPPPQAPPX-LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 666

Query: 382  RDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTW 441
                            PP    V+A   P          PAS P S    P  +A     
Sbjct: 667  ----------------PPPSPPVQAPFSP----------PASPPVSPSATPPSQAP---- 696

Query: 442  LPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSP--- 498
             PS     LQ   S  + PP+    +P P  PP   P A     +P    A PP SP   
Sbjct: 697  -PSLAAPPLQVPPSPPASPPMSPSATPPPQAPP---PLAAPPLQVPPSPPASPPMSPSAT 752

Query: 499  PMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEP--DSAPATSEGQDKGCRGTLPAQE 556
            P P +  + +  P    L VP     + P S  A+P   + PA +          L A  
Sbjct: 753  PPPRVPPLLAAPP----LQVPPSPPASLPMSPLAKPPPQAPPALATPP-------LQALP 801

Query: 557  GPSGSKPLRGSLKEEVALDLS-VRKPTAEASPVKASRSVE-----HAKPTA-AMDVPDVG 609
             P  S P +       +L +S +  P  +A PV A+  ++      A PT  A   P   
Sbjct: 802  SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 861

Query: 610  NMVSDLPGLKKIDTEAPGLPGVPV----TTDAMPRTNFHSSVAFMF-RKFKILRPAPLPA 664
               + + G +     APG P  P     +T + P    HSS A     + +     P   
Sbjct: 862  GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 921

Query: 665  AVVPSTPTSAPAPTQPA-----PTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAV--- 716
            A     P +  A   PA     P P   P+  R     PL         P PPA      
Sbjct: 922  AAASPPPDAELAACHPAAWSRGPAP---PLAFRGAPGAPL---------PWPPATGPGSA 969

Query: 717  --------------ASPAPA---PAPSP------APARAQAPASARDPAPA 744
                          A+PAP    P PSP      A A A A AS+R P  A
Sbjct: 970  DGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQA 1020



 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 172/695 (24%), Positives = 218/695 (31%), Gaps = 103/695 (14%)

Query: 95  RSPAEGPEKMQDSSPVELLPFSPQAHSYPGPPLAAPKPVYRNPLCYGLSTCLGEGAVKRP 154
           R P EGP K   S+           HS        P P  R     G       G ++RP
Sbjct: 199 RPPTEGPRKSVSSA---------SEHS-----TTEPSPAARRRPSAG-------GGLQRP 237

Query: 155 LDVDWTLATGPLL-PSADPPCSL----APA-PSKGQTLDGTFLRGVPAEGSSKDSSGSFS 208
                + +  PL  P+   P +     APA PS+ +      LR        KD++ +  
Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297

Query: 209 PCQPFLEKYQTIHSTGFLASRYTGPYPRNSKQAMSEG-PSSPWTQLAQPLGPPCQDTGP- 266
           P         T   +G  A     P P N+   +    P SP      PL PP     P 
Sbjct: 298 PLSS--SPLATPSPSGTKARPV--PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPS 353

Query: 267 --THYPPPHHPPPHPPQALPCPPACRHPEKQ---------GSYSPALPLQPLGGHKGTGY 315
             T   PP  PP   P ++  PP    P  Q            SP+L   P      +  
Sbjct: 354 LQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQ 413

Query: 316 QAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEPPLT-PRCP-----L 369
               LGSP L+   +     P     +   PS P   P     L+ PL+ P  P     L
Sbjct: 414 ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSL 473

Query: 370 DFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEP 429
             A   LS P     L    A   L    P       +  P   Q +  P     P +  
Sbjct: 474 SPAVSPLSSPLTIHPLQ---ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL 530

Query: 430 VRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALP-PCARECQSLPQ 488
             P  E      LPS     LQ   +  + P +     P PC   A P P        P 
Sbjct: 531 TTPPLEN-----LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS 585

Query: 489 KEDARPPSSPPMPVIDNVFSL-APYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKG 547
                PP +PP      +  L +P    L  P P+A   P      P  AP +       
Sbjct: 586 SIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA---PPXLALPPLQAPPSPPASPPL 642

Query: 548 CRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPD 607
                P+ + P+                L+V    A  SP  +        P A+  V  
Sbjct: 643 SPLATPSPQAPNA---------------LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 687

Query: 608 VGNMVSDLP-GLKKIDTEAPGLPGV--PVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPA 664
                S  P  L     + P  P    P++  A P       +A           AP P 
Sbjct: 688 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA-----------AP-PL 735

Query: 665 AVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPA 724
            V PS P S P      P P   P+    LA  PL V       PSPPA    SP   P 
Sbjct: 736 QVPPSPPASPPMSPSATPPPRVPPL----LAAPPLQVP------PSPPASLPMSPLAKPP 785

Query: 725 PSPAPARAQAPASARDPAPAPAPVAGPAPASTSAP 759
           P   PA A  P  A    PA  P   P   S S P
Sbjct: 786 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 820



 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 167/640 (26%), Positives = 215/640 (33%), Gaps = 79/640 (12%)

Query: 30   SLPHSVGNQDPCTYKGSYFSCPMAGTPKAESEQLASWTPYPPLYSTGMAGPPLQADNLLT 89
            SLP S   Q   +   S  S P+   P      LAS +P  PL S  M  PPL+  + L 
Sbjct: 462  SLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIM--PPLETQSSLA 519

Query: 90   NCLFYRSPAEGPEKMQDSSPVELLPFSPQAHSYP-------GPPLAAPKPVYRNPLCYGL 142
                   PA       ++ P  L P   Q  S P        PP  AP P+   P    L
Sbjct: 520  PPSLQTPPASLTTPPLENLP-SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPS--PL 576

Query: 143  STCLGE---GAVKRPLDVDWTLATGPLLPSADPPCS--LAPAPSKGQTLDGTFLRGVPAE 197
            +T   E        P      LA+ PL     PP S    P P     L    L+  P+ 
Sbjct: 577  TTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP 636

Query: 198  GSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYPRNSKQAMSEGPSSPWTQLAQPL 257
             +S   S   +P  P       +H    L      P P    QA    P+SP      P 
Sbjct: 637  PASPPLSPLATP-SPQAPNALAVH----LLQAPFSPPPSPPVQAPFSPPASP---PVSPS 688

Query: 258  GPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQA 317
              P     P+   PP   PP PP + P  P+   P +      A PLQ            
Sbjct: 689  ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ---------VPP 739

Query: 318  GGLGSPYLRQQAAQAPYIPPLGLDAYPY---PSAPLPAPSPGLKLEPPLTPRCPLDFAPQ 374
                SP +   A   P +PPL L A P    PS P   P   L   PP  P        Q
Sbjct: 740  SPPASPPMSPSATPPPRVPPL-LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ 798

Query: 375  TLSFPYARDDLSLYGASPGLGGTPPSQN---NVRAVPQPGAFQRACQPLPASQPCSEPVR 431
             L  P A        + PG     PS +   +  A P P A      PL    P S P  
Sbjct: 799  ALPSPPA--------SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPPAS 849

Query: 432  PAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCA---------RE 482
            P  +A  +   P        P  S  SGP + +  +P P  PP+  P +           
Sbjct: 850  PTLQAPRRPPTPG-------PDTSV-SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS 901

Query: 483  CQSLPQKEDARPPSSPP------MPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDS 536
              +    E+ R   S P       P  D   +      +   PAP            P  
Sbjct: 902  SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP-W 960

Query: 537  APATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEH 596
             PAT  G   G   T+   EGP  + P  G+L    +   S  K  A A    +SRS + 
Sbjct: 961  PPATGPGSADGLC-TIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 1019

Query: 597  AK----PTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVP 632
            A+    P  A+    V +++S    L   +  A G  G P
Sbjct: 1020 ARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGP 1059



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 69/272 (25%), Positives = 98/272 (36%), Gaps = 47/272 (17%)

Query: 521 PEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRK 580
           P A+   + A    +++P       +    T P   GP G K LR S +E VA   +   
Sbjct: 94  PPASGRGERAPPAKNTSPGPVSSPGRASGTTRP---GPLGQKGLRISAEETVARGKATEA 150

Query: 581 PTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPR 640
           P   A    A R  + + PT     P +          +   TE  GLP    +    P 
Sbjct: 151 PKRSALSAGARR--DTSGPTPGTPSPAMARR------SRAAGTEV-GLPRPAPSARPRPP 201

Query: 641 TNFHSSVAFMFRKFKILRPAPL----PAA------------VVPSTPTSAPAPTQP---- 680
           T           +     P+P     P+A               +TP S+PA + P    
Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 261

Query: 681 ---APTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQ---A 734
              AP   S P    + A +P  VT       + PA+   S +P   PSP+  +A+    
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVT--PPRKDAAPALGPLSSSPLATPSPSGTKARPVPP 319

Query: 735 PASARDPAPAPAPVAGP-------APASTSAP 759
           P +A  P PA  P + P       AP S SAP
Sbjct: 320 PDNAATPLPATLPPSPPLATPLPLAPPSPSAP 351



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 53/211 (25%), Positives = 74/211 (35%), Gaps = 22/211 (10%)

Query: 569 KEEVALDLSVRKPTAEASPVKASRSVEHAKPT-----AAMDVPDVGNMVSDLPGLKKIDT 623
           +++     + R P A A  +   R     +P      AA+ V      V    G K +  
Sbjct: 5   RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAV----GRKPLAE 60

Query: 624 EAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPT----Q 679
            A G+ G  +   A PR     S     R      PA       P    ++P P     +
Sbjct: 61  RAGGIGGATIPESA-PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR 119

Query: 680 PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPA------PAPA-PSPAPARA 732
            + T   GP+G + L            A  +P   A+++ A      P P  PSPA AR 
Sbjct: 120 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 179

Query: 733 QAPASARDPAPAPAPVAGPAPASTSAPGDSL 763
              A      P PAP A P P  T  P  S+
Sbjct: 180 SRAAGTEVGLPRPAPSARPRP-PTEGPRKSV 209



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 35/118 (29%), Positives = 47/118 (39%), Gaps = 17/118 (14%)

Query: 929  DTEAGAVSSSEPTVAR-DEPESLALAQKSPAPKVRKPGRKPPTPGPEKAEAAAGEESCGA 987
            DT      +  P +AR        +    PAP  R    +PPT GP K+ ++A E S   
Sbjct: 163  DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP---RPPTEGPRKSVSSASEHST-T 218

Query: 988  SPTPATSASPP--GPTLKARFRSLLETAWLNGLALPTWGHKSSR--------PDQPSP 1035
             P+PA    P   G   +   RSL  +A    L+ P     S+R        P QP P
Sbjct: 219  EPSPAARRRPSAGGGLQRPASRSLSSSA--TPLSSPARSGPSARGTPRAPAHPSQPKP 274


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 189/813 (23%), Positives = 265/813 (32%), Gaps = 147/813 (18%)

Query: 5    RPLRTLGPVMYGKLPRLETDSGLEHSLPHSVGNQDPCTYKGSYFSCPMAGTPKAESEQLA 64
            RP      ++ G+  +    S  +  +      + P    G   S P    P A+   L 
Sbjct: 280  RPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLT 339

Query: 65   S------WTPYPPLYSTGMAGPPLQADNLLTNCLFYRSPAEGPEKMQDSSPVELLPFSPQ 118
                    T  PP+   G   PP Q             PA+ P +   S      P S Q
Sbjct: 340  KPLAQQPGTVKPPVQPPGTTKPPAQP----------LGPAKPPAQQTGSEK----PSSEQ 385

Query: 119  AHSYPGPP-LAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWTLATGPLLPSADPPCSLA 177
                PGP  LA P  V + P           G  K P     T   G   P A  P   +
Sbjct: 386  ----PGPKALAQPPGVGKTP-------AQQPGPAKPP-----TQQVGTPKPLAQQPGLQS 429

Query: 178  PAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYPRN 237
            PA + G T         P +             QP           G + ++  GP   +
Sbjct: 430  PAKAPGPTK-------TPVQ-------------QP---------GPGKIPAQQAGPGKTS 460

Query: 238  SKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHP----PP--HPPQALPCP----P 287
            ++Q    GP+ P +QL  P  PP Q  GP   PPP  P    PP   P    P P    P
Sbjct: 461  AQQT---GPTKPPSQLPGPAKPPPQQPGPAK-PPPQQPGSAKPPSQQPGSTKPPPQQPGP 516

Query: 288  ACRHPEKQGSYSPALPLQPLGGHKGTGYQ------AGGLGSPYLRQQAAQAPYIPPLGLD 341
            A   P++ GS  P  P Q  G  K +  Q      +    +  + Q  +  P  PP    
Sbjct: 517  AKPSPQQPGSTKP--PSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPT--- 571

Query: 342  AYPYPSAPLPAPSPGLKLEPPLTPRCP----LDFAPQTLSFPYARD----DLSLYGASPG 393
                PSA  P PS G  L   + P C     L   P+  +F    +      SL G +P 
Sbjct: 572  --VSPSAKQP-PSQG--LPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPN 626

Query: 394  LGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPR 453
               T   +          A      P+P+S       +P  +    T   +  K   QP+
Sbjct: 627  PHLTEVKEWLCLNCQMKRALGGDLAPVPSSP------QPKLKTAPVTTTSAVSKSSPQPQ 680

Query: 454  LS---EHSGPPIVIRDSPVPCTPPAL--------PPCARECQSLPQKEDARPPSSPPMPV 502
             +   + + P   +  +P P  PP L         P A+  Q  P+ +    P+ P  P 
Sbjct: 681  QTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQP-PEADSLSKPAPPKEPS 739

Query: 503  IDNVFSLAPYRDYLDVPAPEATTEP-------DSATAEPD--SAPATSEGQDKGCRGTLP 553
            + +    AP  D  D P      +P        SAT +PD  S+   S+ ++K       
Sbjct: 740  VPSEQDKAPVAD--DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKT 797

Query: 554  AQEGPSGSKPLRGSL-----KEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVP-D 607
                PS S P  G        + +    S  K  +   P   S+  +   P    + P  
Sbjct: 798  DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKK 857

Query: 608  VGNMVSDLPGLKKIDTEAPGLPGV-PVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAV 666
                +S  P  K +   +P  PG  P     +P            R+F       L    
Sbjct: 858  AQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFS------LNLGS 911

Query: 667  VPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPS 726
            +   P S P   Q   T      G  I +Q    ++      P   +   A    APAPS
Sbjct: 912  ITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPS 971

Query: 727  PAPARAQAPASARDPAPAPAPVAGPAPASTSAP 759
              P     P S     PAPA  + P    T AP
Sbjct: 972  QPPTSQGPPKSTGQAPPAPAK-SIPVKKETKAP 1003



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 94/377 (24%), Positives = 144/377 (38%), Gaps = 64/377 (16%)

Query: 401 QNNVRAVPQPGAFQRACQPLPASQ-PCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSG 459
           Q     + +P   Q+  +P+P  Q P  +P++  Q+   K+ + S + EK++      S 
Sbjct: 200 QGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQ--QDGTPKS-ISSQQPEKIK------SQ 250

Query: 460 PPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVP 519
           PP     +  P   P   P     + LP + DA  P +    ++    S+ P      +P
Sbjct: 251 PP----GTGKPIQGPTQTPQTDHAK-LPLQRDASRPQTKQADIVRGE-SVKP-----SLP 299

Query: 520 APEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSG-SKPLR---GSLKEEVALD 575
           +P   ++P      P   PA   G +K   G       PSG +KPL    G++K  V   
Sbjct: 300 SP---SKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPP 356

Query: 576 LSVRKPTAEASPVKA-SRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVT 634
            + + P     P K  ++     KP++    P     ++  PG+ K   + PG P  P T
Sbjct: 357 GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA---LAQPPGVGKTPAQQPG-PAKPPT 412

Query: 635 TDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRIL 694
                               ++  P PL       +P  AP PT+   TP   P   +I 
Sbjct: 413 Q-------------------QVGTPKPLAQQPGLQSPAKAPGPTK---TPVQQPGPGKIP 450

Query: 695 AQQP-LSVTCFSLALPSPPAVAVASPAPAPAPSPAPARA--QAPASARDPAPAPAPVA-- 749
           AQQ     T      P+ P   +  PA  P   P PA+   Q P SA+ P+  P      
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP 510

Query: 750 ----GPAPASTSAPGDS 762
               GPA  S   PG +
Sbjct: 511 PQQPGPAKPSPQQPGST 527



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 58/264 (21%), Positives = 95/264 (35%), Gaps = 28/264 (10%)

Query: 519 PAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQ---EGPSGSKPLRGSLKE----- 570
           P  +   +P      P   P   +G  K      P +   + P   KP++G  +      
Sbjct: 210 PLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDH 269

Query: 571 -EVALDLSVRKPTAEASPVKASRSVEHAKPTAA---MDVPDVGNMVSDLPGLKKIDTEAP 626
            ++ L     +P  + + +    SV+ + P+ +   +  P  G   +  PG +K     P
Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEK-SQPGP 328

Query: 627 GLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPA--PLPAAVVPSTPTSAPAPT--QPAP 682
             P    +    P      +V    +     +P   PL  A  P+  T +  P+  QP P
Sbjct: 329 AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGP 388

Query: 683 TPTSGPIGL-RILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASARDP 741
              + P G+ +  AQQP            PP   V +P P        + A+AP   + P
Sbjct: 389 KALAQPPGVGKTPAQQP--------GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440

Query: 742 APAPAPVAGPAPASTSAPGDSLEQ 765
              P P  G  PA  + PG +  Q
Sbjct: 441 VQQPGP--GKIPAQQAGPGKTSAQ 462



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 42/132 (31%), Positives = 48/132 (36%), Gaps = 13/132 (9%)

Query: 254  AQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGT 313
            AQP  PP     P   PPP  PPP PP   P  P     +K    SP     PL     T
Sbjct: 2403 AQPPPPPPPPPPPPPPPPPPPPPPLPPPTSP-KPTILPKKKLTVASPVTTATPLFDAVTT 2461

Query: 314  GYQAGGL---GSPYLRQQAAQAPYIPP--------LGLDAYPYPSAPLPAPSPGLKLEPP 362
                  L   G P  R      P +PP        L     P PS P  AP P +  + P
Sbjct: 2462 LETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIP-QLP 2520

Query: 363  LTPRCPLDFAPQ 374
             T + P D  P+
Sbjct: 2521 TTTQKPTDIHPK 2532



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 80/331 (24%), Positives = 119/331 (35%), Gaps = 59/331 (17%)

Query: 508  SLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGP--------- 558
            S+  Y + + V   + T  PD   +      + S+         +P  EGP         
Sbjct: 2235 SIIDYPEEISVSL-DRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDL 2293

Query: 559  --SGSKPLRGSLKEE------VALDLSVRKPTAEASPVKASRS--VEHAKPTAAMDVPDV 608
              S   P++ + KE         L+    K   EA   K+S S  V    P++ + +P  
Sbjct: 2294 LISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMK 2353

Query: 609  GNMVS------DLPGLKKIDTEAP-GLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAP 661
              + +      +  G +K  ++ P G P V  +  A PR  F SS   +  +     P P
Sbjct: 2354 EQLSTTYFTSGETFGQEKPASQLPSGSPSVS-SLPAKPRPFFRSSSLDISAQ-----PPP 2407

Query: 662  LPAAVVPSTPTSAPAPTQPAPTPTSG----------PIGLRILAQQPL--SVTCF----- 704
             P    P  P   P P  P P PTS            +   +    PL  +VT       
Sbjct: 2408 PPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAV 2467

Query: 705  --SLALPSPPAVAVASPAPAPAPSPAPAR---AQAPASARDPAPAPAPVAGPAPASTSAP 759
              S  LP       A P   P PS  P+       P  ++ P  AP PV    P +T  P
Sbjct: 2468 LRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPI-APKPVIPQLPTTTQKP 2526

Query: 760  GDSLEQHFTGLHASLCDAISGSVAHSPPEKL 790
             D +    TGL  SL  +++ ++  S   KL
Sbjct: 2527 TD-IHPKPTGL--SLTSSMTLNLVTSADYKL 2554


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 189/813 (23%), Positives = 265/813 (32%), Gaps = 147/813 (18%)

Query: 5    RPLRTLGPVMYGKLPRLETDSGLEHSLPHSVGNQDPCTYKGSYFSCPMAGTPKAESEQLA 64
            RP      ++ G+  +    S  +  +      + P    G   S P    P A+   L 
Sbjct: 280  RPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLT 339

Query: 65   S------WTPYPPLYSTGMAGPPLQADNLLTNCLFYRSPAEGPEKMQDSSPVELLPFSPQ 118
                    T  PP+   G   PP Q             PA+ P +   S      P S Q
Sbjct: 340  KPLAQQPGTVKPPVQPPGTTKPPAQP----------LGPAKPPAQQTGSEK----PSSEQ 385

Query: 119  AHSYPGPP-LAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWTLATGPLLPSADPPCSLA 177
                PGP  LA P  V + P           G  K P     T   G   P A  P   +
Sbjct: 386  ----PGPKALAQPPGVGKTP-------AQQPGPAKPP-----TQQVGTPKPLAQQPGLQS 429

Query: 178  PAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYPRN 237
            PA + G T         P +             QP           G + ++  GP   +
Sbjct: 430  PAKAPGPTK-------TPVQ-------------QP---------GPGKIPAQQAGPGKTS 460

Query: 238  SKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHP----PP--HPPQALPCP----P 287
            ++Q    GP+ P +QL  P  PP Q  GP   PPP  P    PP   P    P P    P
Sbjct: 461  AQQT---GPTKPPSQLPGPAKPPPQQPGPAK-PPPQQPGSAKPPSQQPGSTKPPPQQPGP 516

Query: 288  ACRHPEKQGSYSPALPLQPLGGHKGTGYQ------AGGLGSPYLRQQAAQAPYIPPLGLD 341
            A   P++ GS  P  P Q  G  K +  Q      +    +  + Q  +  P  PP    
Sbjct: 517  AKPSPQQPGSTKP--PSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPT--- 571

Query: 342  AYPYPSAPLPAPSPGLKLEPPLTPRCP----LDFAPQTLSFPYARD----DLSLYGASPG 393
                PSA  P PS G  L   + P C     L   P+  +F    +      SL G +P 
Sbjct: 572  --VSPSAKQP-PSQG--LPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPN 626

Query: 394  LGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPR 453
               T   +          A      P+P+S       +P  +    T   +  K   QP+
Sbjct: 627  PHLTEVKEWLCLNCQMKRALGGDLAPVPSSP------QPKLKTAPVTTTSAVSKSSPQPQ 680

Query: 454  LS---EHSGPPIVIRDSPVPCTPPAL--------PPCARECQSLPQKEDARPPSSPPMPV 502
             +   + + P   +  +P P  PP L         P A+  Q  P+ +    P+ P  P 
Sbjct: 681  QTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQP-PEADSLSKPAPPKEPS 739

Query: 503  IDNVFSLAPYRDYLDVPAPEATTEP-------DSATAEPD--SAPATSEGQDKGCRGTLP 553
            + +    AP  D  D P      +P        SAT +PD  S+   S+ ++K       
Sbjct: 740  VPSEQDKAPVAD--DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKT 797

Query: 554  AQEGPSGSKPLRGSL-----KEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVP-D 607
                PS S P  G        + +    S  K  +   P   S+  +   P    + P  
Sbjct: 798  DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKK 857

Query: 608  VGNMVSDLPGLKKIDTEAPGLPGV-PVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAV 666
                +S  P  K +   +P  PG  P     +P            R+F       L    
Sbjct: 858  AQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFS------LNLGS 911

Query: 667  VPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPS 726
            +   P S P   Q   T      G  I +Q    ++      P   +   A    APAPS
Sbjct: 912  ITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPS 971

Query: 727  PAPARAQAPASARDPAPAPAPVAGPAPASTSAP 759
              P     P S     PAPA  + P    T AP
Sbjct: 972  QPPTSQGPPKSTGQAPPAPAK-SIPVKKETKAP 1003



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 94/377 (24%), Positives = 144/377 (38%), Gaps = 64/377 (16%)

Query: 401 QNNVRAVPQPGAFQRACQPLPASQ-PCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSG 459
           Q     + +P   Q+  +P+P  Q P  +P++  Q+   K+ + S + EK++      S 
Sbjct: 200 QGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQ--QDGTPKS-ISSQQPEKIK------SQ 250

Query: 460 PPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVP 519
           PP     +  P   P   P     + LP + DA  P +    ++    S+ P      +P
Sbjct: 251 PP----GTGKPIQGPTQTPQTDHAK-LPLQRDASRPQTKQADIVRGE-SVKP-----SLP 299

Query: 520 APEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSG-SKPLR---GSLKEEVALD 575
           +P   ++P      P   PA   G +K   G       PSG +KPL    G++K  V   
Sbjct: 300 SP---SKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPP 356

Query: 576 LSVRKPTAEASPVKA-SRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVT 634
            + + P     P K  ++     KP++    P     ++  PG+ K   + PG P  P T
Sbjct: 357 GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA---LAQPPGVGKTPAQQPG-PAKPPT 412

Query: 635 TDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRIL 694
                               ++  P PL       +P  AP PT+   TP   P   +I 
Sbjct: 413 Q-------------------QVGTPKPLAQQPGLQSPAKAPGPTK---TPVQQPGPGKIP 450

Query: 695 AQQP-LSVTCFSLALPSPPAVAVASPAPAPAPSPAPARA--QAPASARDPAPAPAPVA-- 749
           AQQ     T      P+ P   +  PA  P   P PA+   Q P SA+ P+  P      
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP 510

Query: 750 ----GPAPASTSAPGDS 762
               GPA  S   PG +
Sbjct: 511 PQQPGPAKPSPQQPGST 527



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 58/264 (21%), Positives = 95/264 (35%), Gaps = 28/264 (10%)

Query: 519 PAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQ---EGPSGSKPLRGSLKE----- 570
           P  +   +P      P   P   +G  K      P +   + P   KP++G  +      
Sbjct: 210 PLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDH 269

Query: 571 -EVALDLSVRKPTAEASPVKASRSVEHAKPTAA---MDVPDVGNMVSDLPGLKKIDTEAP 626
            ++ L     +P  + + +    SV+ + P+ +   +  P  G   +  PG +K     P
Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEK-SQPGP 328

Query: 627 GLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPA--PLPAAVVPSTPTSAPAPT--QPAP 682
             P    +    P      +V    +     +P   PL  A  P+  T +  P+  QP P
Sbjct: 329 AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGP 388

Query: 683 TPTSGPIGL-RILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASARDP 741
              + P G+ +  AQQP            PP   V +P P        + A+AP   + P
Sbjct: 389 KALAQPPGVGKTPAQQP--------GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440

Query: 742 APAPAPVAGPAPASTSAPGDSLEQ 765
              P P  G  PA  + PG +  Q
Sbjct: 441 VQQPGP--GKIPAQQAGPGKTSAQ 462



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 42/132 (31%), Positives = 48/132 (36%), Gaps = 13/132 (9%)

Query: 254  AQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGT 313
            AQP  PP     P   PPP  PPP PP   P  P     +K    SP     PL     T
Sbjct: 2403 AQPPPPPPPPPPPPPPPPPPPPPPLPPPTSP-KPTILPKKKLTVASPVTTATPLFDAVTT 2461

Query: 314  GYQAGGL---GSPYLRQQAAQAPYIPP--------LGLDAYPYPSAPLPAPSPGLKLEPP 362
                  L   G P  R      P +PP        L     P PS P  AP P +  + P
Sbjct: 2462 LETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIP-QLP 2520

Query: 363  LTPRCPLDFAPQ 374
             T + P D  P+
Sbjct: 2521 TTTQKPTDIHPK 2532



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 80/331 (24%), Positives = 119/331 (35%), Gaps = 59/331 (17%)

Query: 508  SLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGP--------- 558
            S+  Y + + V   + T  PD   +      + S+         +P  EGP         
Sbjct: 2235 SIIDYPEEISVSL-DRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDL 2293

Query: 559  --SGSKPLRGSLKEE------VALDLSVRKPTAEASPVKASRS--VEHAKPTAAMDVPDV 608
              S   P++ + KE         L+    K   EA   K+S S  V    P++ + +P  
Sbjct: 2294 LISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMK 2353

Query: 609  GNMVS------DLPGLKKIDTEAP-GLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAP 661
              + +      +  G +K  ++ P G P V  +  A PR  F SS   +  +     P P
Sbjct: 2354 EQLSTTYFTSGETFGQEKPASQLPSGSPSVS-SLPAKPRPFFRSSSLDISAQ-----PPP 2407

Query: 662  LPAAVVPSTPTSAPAPTQPAPTPTSG----------PIGLRILAQQPL--SVTCF----- 704
             P    P  P   P P  P P PTS            +   +    PL  +VT       
Sbjct: 2408 PPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAV 2467

Query: 705  --SLALPSPPAVAVASPAPAPAPSPAPAR---AQAPASARDPAPAPAPVAGPAPASTSAP 759
              S  LP       A P   P PS  P+       P  ++ P  AP PV    P +T  P
Sbjct: 2468 LRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPI-APKPVIPQLPTTTQKP 2526

Query: 760  GDSLEQHFTGLHASLCDAISGSVAHSPPEKL 790
             D +    TGL  SL  +++ ++  S   KL
Sbjct: 2527 TD-IHPKPTGL--SLTSSMTLNLVTSADYKL 2554


>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
          Length = 962

 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 124/515 (24%), Positives = 169/515 (32%), Gaps = 106/515 (20%)

Query: 264 TGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSP 323
           +G     P   P P PP  LP P   R    +  +S AL             + GG+   
Sbjct: 280 SGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSALT---------ASVEEGGVPG- 329

Query: 324 YLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARD 383
              +  +  P  P L            P  +P L++EPP  P  P +  P         D
Sbjct: 330 ---EDPSSRPATPELA----------EPESAPTLRVEPPSPPEGPPNPGP---------D 367

Query: 384 DLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLP 443
                G +P  G   P+ +    V    A +    P P + P  +   P  +    +  P
Sbjct: 368 GGKQDGEAPPAGPCAPATDKAEEV--VCAPEDVASPFPTAIPEGDTTPPETDPAATSEAP 425

Query: 444 SCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVI 503
           S R            GP   +     P TPP LP            E+  PP   P    
Sbjct: 426 SAR-----------DGPERSVPKEAEP-TPPVLP-----------DEEKGPPGPAP---- 458

Query: 504 DNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLP--AQEGPSGS 561
                  P R+    P   A TEP+    EP +APA S    K C    P  A EGP+ S
Sbjct: 459 ------EPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAAS 512

Query: 562 KPLR-----------GSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGN 610
            PL            GSL  E A     +   AEA P  A R+    K            
Sbjct: 513 PPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERG-------- 564

Query: 611 MVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPST 670
             ++L G KK             +  A PR      +     +  + R  P+  +     
Sbjct: 565 -GAELRGAKKFSVS---------SCRARPRPGVSRPLERASGRLPLARSGPVWRS----- 609

Query: 671 PTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAP-SPAP 729
             +A    Q  P P     G R LA++    +    A P+ P  +    A AP    P P
Sbjct: 610 -EAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCP 668

Query: 730 ARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLE 764
           A AQ PA + D  P P  +   + +     G S E
Sbjct: 669 A-AQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQE 702



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 103/403 (25%), Positives = 136/403 (33%), Gaps = 70/403 (17%)

Query: 434 QEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRD-SPVPCTPPALPPC--ARECQSLPQKE 490
           +E EEK  L      ++ P     SG   V  D  P P  P  LPP   AR  ++  Q  
Sbjct: 262 EENEEKPLL------EVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHS 315

Query: 491 DARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRG 550
            A   S     V        P  D    PA     EP+SA       P+  EG       
Sbjct: 316 SALTASVEEGGV--------PGEDPSSRPATPELAEPESAPTLRVEPPSPPEG------- 360

Query: 551 TLPAQEGPSGSK------------PLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAK 598
             P   GP G K            P     +E V     V  P   A P +   +     
Sbjct: 361 --PPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIP-EGDTTPPETD 417

Query: 599 PTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILR 658
           P A  + P       D P  + +  EA   P  PV  D        +       + +  R
Sbjct: 418 PAATSEAPSA----RDGPE-RSVPKEAEPTP--PVLPDEEKGPPGPAPEPEREAETEPER 470

Query: 659 PAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVAS 718
            A      + + P++APAP+ PAP           L  +P + +    A  SPP  A  S
Sbjct: 471 GAGTEPERIGTEPSTAPAPSPPAPKSC--------LKHRPAAASEGPAA--SPPLAAAES 520

Query: 719 PAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQHFTGLHASLCDAI 778
           P   P P    A A AP   +    A    A PA A  +AP    E+    L  +   ++
Sbjct: 521 PPVEPGPGSLDAEAAAPERPK----AERAEAPPAGAERAAPERKAERGGAELRGAKKFSV 576

Query: 779 SGSVAHSPPEKLREW--------LETAGP-W-GQAAWQDCQGV 811
           S   A   P   R          L  +GP W  +AA  D QG+
Sbjct: 577 SSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGL 619



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 35/115 (30%), Positives = 43/115 (37%), Gaps = 12/115 (10%)

Query: 931  EAGAVSSSEPTVARDEPESLALAQKSPAPKVRKPGRK-PPTPGPEKAEAAAGE------- 982
            E    ++SE   ARD PE     +  P P V     K PP P PE    A  E       
Sbjct: 415  ETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGT 474

Query: 983  --ESCGASPTPATSASPPGPTLKARFRSLLETAWLNGLALPTWGHKSSRPDQPSP 1035
              E  G  P+ A + SPP P  K+  +     A     A P      S P +P P
Sbjct: 475  EPERIGTEPSTAPAPSPPAP--KSCLKHRPAAASEGPAASPPLAAAESPPVEPGP 527


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 125/503 (24%), Positives = 183/503 (36%), Gaps = 78/503 (15%)

Query: 270   PPPHHPPPH----PPQ-ALPCPPACRHPEKQGSYSPAL---PLQPLGGHKGTGYQAGGLG 321
             P P  PPP     P + AL  PPA    E + +  P +   P +P+   K          
Sbjct: 10656 PKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAV------ 10709

Query: 322   SPYLRQQAAQAPYIPPLGLDAYP---YPSAPLPAPSPGLKLEPPL-TPRCPLDFAPQTLS 377
                     A+ P +PP+ +   P    P   +P   P     PP   P  P +  P+   
Sbjct: 10710 -------VAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKV 10762

Query: 378   FPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEA- 436
                 + ++      P +   P  +    AVP P   +RA  P P      E + P +E  
Sbjct: 10763 AVPKKPEVPP-AKVPEVPKKPVLEEKP-AVPVP---ERAESPPPEVYEEPEEIAPEEEIA 10817

Query: 437   -EEKTWLPSCRKEKLQ---PRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDA 492
              EE+  +P   +E+ +   P + E     I  +  PV   P A PP   E + + +K   
Sbjct: 10818 PEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKL 10877

Query: 493   --RPPSSPPMP----VIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDK 546
               RPP  PP P    V + +F L   +       PE    P+     P   P    G +K
Sbjct: 10878 KPRPPPPPPAPPKEDVKEKIFQL---KAIPKKKVPEKPQVPEKVELTPLKVP----GGEK 10930

Query: 547   GCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVP 606
               R  LP +      KP     KEEV L   +RK   E  P    + +E  K  A  + P
Sbjct: 10931 KVRKLLPER------KP---EPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPP 10981

Query: 607   DVGNMVS-DLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAA 665
                 +   ++P + K + + P    VP    A+P                   P P P A
Sbjct: 10982 PPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIP--------------LPAPEPKPKPEA 11027

Query: 666   VVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQP-LSVTCFSLALPSPPAVAVASPAPAPA 724
              V    T  P P +P PTP + P+ + ++ ++          A P  P   V  P   P+
Sbjct: 11028 EVK---TIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGV--PKKTPS 11082

Query: 725   PSPAPARAQAPASARDPAPAPAP 747
             P  A  R   P S  +  P  AP
Sbjct: 11083 PIEAERRKLRPGSGGEKPPDEAP 11105



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 121/538 (22%), Positives = 185/538 (34%), Gaps = 88/538 (16%)

Query: 271   PPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQQAA 330
             PP   P  PP  +P  P    PEK+     A+P +P               +P       
Sbjct: 10541 PPPKKPEVPPTKVPEVPKAAVPEKK--VPEAIPPKPESPPPEVPE------APKEVVPEK 10592

Query: 331   QAPYIPPLGLDAYPY--PSAPLPA-PSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSL 387
             + P  PP   +  P   P AP    P   + + PP  P  P    P+      A  +  +
Sbjct: 10593 KVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKV--AVPEKKV 10650

Query: 388   YGASPGLGGTPPSQ--------------NNVRAVPQPGAFQRACQPLPASQPCSEPVRPA 433
               A P    +PP +                V   P+P A  +    +P  +P  E   PA
Sbjct: 10651 PEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVT--VPPKKPVPEKKAPA 10708

Query: 434   QEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPA-LPPCARECQ-----SLP 487
               A+ K  LP  +  ++   +      P+V+   P    PPA +P   +E       ++P
Sbjct: 10709 VVAK-KPELPPVKVPEVPKEVVPEKKVPLVVPKKPE--APPAKVPEVPKEVVPEKKVAVP 10765

Query: 488   QKEDARP---PSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQ 544
             +K +  P   P  P  PV++   ++ P  +  + P PE   EP+    E + AP   +  
Sbjct: 10766 KKPEVPPAKVPEVPKKPVLEEKPAV-PVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPV 10824

Query: 545   DKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSV---RKPTAEASPVKA---SRSVEHAK 598
                    +  +E P    P      +++  +  V   +KP  EA P K     + +E  K
Sbjct: 10825 P------VAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKP--EAPPPKEPEPEKVIEKPK 10876

Query: 599   -------PTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMF 651
                    P  A    DV   +  L  + K   + P  P VP   +  P       V    
Sbjct: 10877 LKPRPPPPPPAPPKEDVKEKIFQLKAIPK--KKVPEKPQVPEKVELTPL-----KVPGGE 10929

Query: 652   RKFKIL----RPAPLPAAVVPSTPTSAPAPTQPA-----------PTPTSGPIGLRILAQ 696
             +K + L    +P P    V+ S     P   +P            P     P    +   
Sbjct: 10930 KKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEV 10989

Query: 697   QPLSVTCFSLALPSP---PAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGP 751
             +  +VT     +P P   P +  A P PAP P P P             P P P+A P
Sbjct: 10990 EVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAP 11047



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 90/433 (20%), Positives = 134/433 (30%), Gaps = 97/433 (22%)

Query: 344   PYPSAPLPAPSPGLKLEPPL----TPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPP 399
             P P    P P P  K  PP      P+ P +  P  +               P     PP
Sbjct: 9957  PVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLI---------------PKKEKPPP 10001

Query: 400   SQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSG 459
             ++  V  VP+    +    P+P  +    P     E  +K   P   K+   P   +   
Sbjct: 10002 AK--VPEVPKKPVPEEKV-PVPVPKKVEAPPAKVPEVPKK---PVPEKKVPVPAPKKVEA 10055

Query: 460   PPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVP 519
             PP     + VP  P  L P  ++   +P+K +A PP  P              +    VP
Sbjct: 10056 PP-----AKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVP--------------KKREPVP 10096

Query: 520   APEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVR 579
              P A  + +    E +  P             LP +E     +       EEV  +    
Sbjct: 10097 VPVALPQEEEVLFEEEIVPEEE---------VLPEEEEVLPEE-------EEVLPEEEEV 10140

Query: 580   KPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMP 639
              P  E  P +     E   P     VP+    V +   L ++  + P    VP     + 
Sbjct: 10141 LPEEEEIPPE-----EEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVT 10195

Query: 640   RTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPA------------PTQPAPTPTSG 687
                         +K  I +    P A VP  P                 P +    P   
Sbjct: 10196 E-----------KKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEE 10244

Query: 688   PIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPAS--------AR 739
             PI    + ++P S+       P P    V   A   AP+P P + +AP +         +
Sbjct: 10245 PISEEEIPEEPPSIEEVEEVAP-PRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEK 10303

Query: 740   DPAPAPAPVAGPA 752
              P P     A PA
Sbjct: 10304 VPVPVQKKEAPPA 10316



 Score = 37.7 bits (86), Expect = 0.057
 Identities = 78/358 (21%), Positives = 123/358 (34%), Gaps = 49/358 (13%)

Query: 428   EPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIV--IRDSPVPCTPPALP-------- 477
             EP     + EE       R E+ +  ++E   P  V  + + PVP  P A P        
Sbjct: 9760  EPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAV 9819

Query: 478   PCARECQSLPQKEDARPPSSP--PMPVIDNVFSLA---PYRDYLDVPAPEATTEPDSATA 532
             P  +    +P+K    PP  P  P  V +    ++     ++ +  PA +   +P    A
Sbjct: 9820  PEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVA 9879

Query: 533   EPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASR 592
             E +  P       K     +   E P   +P   + +EEV   +       E   +    
Sbjct: 9880  E-EKVPVPR----KEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEE 9934

Query: 593   SV---EHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAF 649
                  E   P   + VP+V      +P  KK           P     +P+         
Sbjct: 9935  EFITEEEVVPVIPVKVPEVPR--KPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVL 9992

Query: 650   MFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPT---SGPIGLRILAQQPLSVTCFSL 706
             + +K K   P P     VP  P   P    P P P    + P  +  + ++P+      +
Sbjct: 9993  IPKKEK---PPPAKVPEVPKKPV--PEEKVPVPVPKKVEAPPAKVPEVPKKPVPEK--KV 10045

Query: 707   ALPSPPAVAVASPAPAPA-----------PSPAPARAQAPAS--ARDPAPAPAPVAGP 751
              +P+P  V  A PA  P            P+P P + +AP     +   P P PVA P
Sbjct: 10046 PVPAPKKVE-APPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALP 10102



 Score = 37.0 bits (84), Expect = 0.097
 Identities = 86/423 (20%), Positives = 147/423 (34%), Gaps = 47/423 (11%)

Query: 333  PYIPPLGLDAYPYPSAPLPAPSPGLKLEPPL-----TPRCPLDFAPQTLSFPYARDDLSL 387
            P +P L     P   AP+P P    K+EPP       P+ P+    + +  P        
Sbjct: 9286 PKVPELPEKPAPEEVAPVPIPK---KVEPPAPKVPEVPKKPVPEEKKPVPVPKKEP---- 9338

Query: 388  YGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRK 447
              A P +   P        +P P A ++   P    +     V+     EEK  + + R+
Sbjct: 9339 -AAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPE-----VQKGVVTEEKITIVTQRE 9392

Query: 448  EKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVF 507
            E   P + E     +     PVP     +PP   +  +LP+K       + P+PV     
Sbjct: 9393 ESPPPAVPEIPKKKVPEERKPVPRKEEEVPP-PPKVPALPKKPVPEEKVAVPVPVAKKA- 9450

Query: 508  SLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGS 567
               P R  +   + +   E     AE   + A  + + +  R  + A+E  S S      
Sbjct: 9451 --PPPRAEV---SKKTVVEEKRFVAEEKLSFAVPQ-RVEVTRHEVSAEEEWSYS------ 9498

Query: 568  LKEEVALDLSV-----RKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPG--LKK 620
             +EE  + +SV     R+   EA   +     E  +      +  +   V   P    ++
Sbjct: 9499 -EEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTER 9557

Query: 621  IDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQP 680
             + +    P +P   +  P      +   +  + K+  PAP+P       P     P +P
Sbjct: 9558 QEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKV--PAPVPKKEKVPPPKVPEEPKKP 9615

Query: 681  APTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASARD 740
             P     P  +++    P  VT   + +     V V     A     AP +A+ P   + 
Sbjct: 9616 VPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLV-----AVTKKEAPPKARVPEEPKR 9670

Query: 741  PAP 743
              P
Sbjct: 9671 AVP 9673



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 74/344 (21%), Positives = 112/344 (32%), Gaps = 63/344 (18%)

Query: 398   PPSQNNVRAVPQPGAFQRACQPLPAS---QPCSEPVRPAQEAEEKTWLPSCRKEKLQPRL 454
             PP++   +AVP+    ++   P+P      P   P  P +  EEK  +   ++EK Q   
Sbjct: 9810  PPAKVLKKAVPE----EKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQ--- 9862

Query: 455   SEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMP-------VIDNVF 507
                    +    + VP  P  +   A E   +P+KE A P   P +P       V     
Sbjct: 9863  -------VTEPAAKVPMKPKRV--VAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEE 9913

Query: 508   SLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGS 567
              +    +YL     E   E +    E +  P       +     +P +  P   KP+   
Sbjct: 9914  VVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPE-----VPRKPVPEEKKPVPVP 9968

Query: 568   LKEEV--ALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEA 625
              K+E   A    V K   E  PV   +  E   P    +VP            K +  E 
Sbjct: 9969  KKKEAPPAKVPEVPKKPEEKVPVLIPKK-EKPPPAKVPEVPK-----------KPVPEEK 10016

Query: 626   PGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPT 685
               +P VP   +A P                  +   +P   VP      PAP +    P 
Sbjct: 10017 VPVP-VPKKVEAPPA-----------------KVPEVPKKPVPEKKVPVPAPKKVEAPPA 10058

Query: 686   SGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAP 729
               P   + L  +    T     + +PP        P P P   P
Sbjct: 10059 KVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALP 10102



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 67/319 (21%), Positives = 101/319 (31%), Gaps = 97/319 (30%)

Query: 253   LAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPP----------ACRHPEKQGSYSPAL 302
             + +P  PP ++  P          P PP   P PP              P+K+    P +
Sbjct: 10855 IKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQV 10914

Query: 303   P----LQPL---GGHKGT----------GYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPY 345
             P    L PL   GG K              +   L S   ++   + P + P  L+    
Sbjct: 10915 PEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKK 10974

Query: 346   PSAP-LPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNNV 404
             P+ P  P P P  ++E P   +                                      
Sbjct: 10975 PAVPEPPPPKPVEEVEVPTVTK------------------------------------RE 10998

Query: 405   RAVPQPGAFQ--RACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPI 462
             R +P+P      +   PLPA +P     +P  EAE KT  P                PP+
Sbjct: 10999 RKIPEPTKVPEIKPAIPLPAPEP-----KPKPEAEVKTIKP----------------PPV 11037

Query: 463   VIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPE 522
                 +P+   P  +P   ++ ++   KE+A  P  P   V        P +    + A  
Sbjct: 11038 EPEPTPI-AAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGV--------PKKTPSPIEAER 11088

Query: 523   ATTEPDSATAE-PDSAPAT 540
                 P S   + PD AP T
Sbjct: 11089 RKLRPGSGGEKPPDEAPFT 11107



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 940   PTVARDEPESLALAQKSPAPKVRKPGRKPPTPGPEKAEAAAGEESCGASPTPATSASPP 998
             P    + P+ +   +K P P  +KP   PPT  PE  +AA  E+    +  P   + PP
Sbjct: 10522 PPKVPEAPKEVVPEKKVPVPPPKKP-EVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPP 10579



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 41/158 (25%), Positives = 59/158 (37%), Gaps = 30/158 (18%)

Query: 662 LPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAP 721
           LP    P  P   P P   +PTP S     ++  QQ           PSP   + +    
Sbjct: 249 LPHKTPPRIP---PKPKSRSPTPPSIAAKAQLARQQS----------PSPIRHSPSPVRH 295

Query: 722 APAPSPAPARAQAPASARDPAPAPAPVAGP-----APASTSAPGDSLEQHFTGLHASLCD 776
             AP+P+P R+ +PA+    +P  + V  P       AST A G  +   +         
Sbjct: 296 VRAPTPSPVRSVSPAARISTSPIRS-VRSPLLMRKTQASTVATGPEVPPPWKQ------- 347

Query: 777 AISGSVAHSPPEKLREWLETAGPW--GQAAWQDCQGVQ 812
              G VA S   ++RE   T       +  W+   GVQ
Sbjct: 348 --EGYVASSSEAEMRETTLTTSTQIRTEERWEGRYGVQ 383



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 17/59 (28%), Positives = 26/59 (44%), Gaps = 1/59 (1%)

Query: 940   PTVARDEPESLALAQKSPAPKVRKPGRKPPTPGPEKAEAAAGEESCGASPTPATSASPP 998
             P    + P+ +   +K P P  +KP   PPT  PE  + A  E+    +  P   + PP
Sbjct: 10606 PVKVPEAPKEVVPEKKVPVPPPKKP-EVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPP 10663


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 92/416 (22%), Positives = 125/416 (30%), Gaps = 77/416 (18%)

Query: 344  PYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNN 403
            P  + P P P+    L P  TP  P                      +P    TP     
Sbjct: 1401 PPTTTPSPPPTSTTTLPPTTTPSPPTTTT-----------------TTPPPTTTPSPPIT 1443

Query: 404  VRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIV 463
                P P        P P     + P  P       T  PS       P  +  + PP  
Sbjct: 1444 TTTTPPP-----TTTPSPPISTTTTPP-PTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPT 1497

Query: 464  IRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEA 523
               SP P T P  PP +             PP++ P P      +  P       P+P  
Sbjct: 1498 TTPSP-PTTTPITPPASTT---------TLPPTTTPSPPTTTTTTPPP----TTTPSPPT 1543

Query: 524  TTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTA 583
            TT     T+     P T+         T P    PS   P   +      +  +   PT 
Sbjct: 1544 TTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPS---PPTTTTPSPPTITTTTPPPTT 1600

Query: 584  EASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNF 643
              SP   + +     PT     P    +           T  P  P  P TT   P T  
Sbjct: 1601 TPSPPTTTTTTP--PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP--PTTTTTPPPTT- 1655

Query: 644  HSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTC 703
                           P+P P    PS P +      P  TP+S           P++ T 
Sbjct: 1656 --------------TPSP-PTTTTPSPPITTTTTPPPTTTPSS-----------PITTT- 1688

Query: 704  FSLALPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAP 759
                 PSPP   + +P+P   PS        P+S   P+P P  +  P+P +T +P
Sbjct: 1689 -----PSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSP 1739



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 143/733 (19%), Positives = 212/733 (28%), Gaps = 106/733 (14%)

Query: 67   TPYPPLYSTGMAGPPLQADNLLTNCLFYRSPAEGPEKMQDS-SPVELLPFSPQAHSYPGP 125
            TP PP+ +T    PP    +   +      P   P     + SP    P  P   +   P
Sbjct: 1437 TPSPPITTT-TTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPP 1495

Query: 126  PLAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWTLATGPLLPSADPPCSLAPAPSKGQT 185
            P   P P    P+    ST         P     T  T P   +  PP +    P    T
Sbjct: 1496 PTTTPSPPTTTPITPPASTTTLPPTTT-PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT 1554

Query: 186  LDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYPRNSKQAMSEG 245
                     P   ++     + +P  P          T       T P P  +       
Sbjct: 1555 TLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPP 1614

Query: 246  PSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQ 305
             ++P      P+ PP   T  T  PP   P P PP     PP    P    + +P+ P+ 
Sbjct: 1615 TTTPSPPTTTPITPP---TSTTTLPPTTTPSP-PPTTTTTPPPTTTPSPPTTTTPSPPIT 1670

Query: 306  PLGGHKGTGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEPPLTP 365
                                       P  PP    + P  + P P  +      P  TP
Sbjct: 1671 -----------------------TTTTP--PPTTTPSSPITTTPSPPTTTMTTPSPTTTP 1705

Query: 366  RCPLDFA--PQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPAS 423
              P+     P + + P +    ++   SP    +PP+       P   +      PLP S
Sbjct: 1706 SSPITTTTTPSSTTTP-SPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPS 1764

Query: 424  ------QPCSE--PVRPAQEAEEKT-WLPSCRKEKLQPR-----LSEHSGPPIVIRDSPV 469
                   P S   P  P       T WL S +    +P      + +  GP      S  
Sbjct: 1765 ITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCR 1824

Query: 470  PCTPPALP--------PCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAP 521
                P +P         C      + + ED +P    PM    N          ++V   
Sbjct: 1825 ATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNY--------EINVQCC 1876

Query: 522  EATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKP 581
            E  T+P + T      P            T+     P+G++                   
Sbjct: 1877 ECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQ------------------- 1917

Query: 582  TAEASPVKASRSVEHAKPTAAMDVPD---VGNMVSDLPGLKKIDTEAPGLPGVPVTTDAM 638
            T   +P+  + +V           P    +    +  P      T+ P    +  TT   
Sbjct: 1918 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 1977

Query: 639  PR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILA 695
            P    T   +           + P P P      TPT+ P  T    TPT  P G +   
Sbjct: 1978 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPT 2035

Query: 696  QQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARAQAP-----ASARDPAP 743
              P++ T  +   P+P      +P   P        P+P P   Q P      +     P
Sbjct: 2036 TTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2093

Query: 744  APAPVAGPAPAST 756
             P P     P +T
Sbjct: 2094 TPTPTGTQTPTTT 2106



 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 134/692 (19%), Positives = 197/692 (28%), Gaps = 74/692 (10%)

Query: 108  SPVELLPFSPQAHSYPGPPLAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWTLATGPLL 167
            SP    P  P   +   PP   P P          +T               T  + P+ 
Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIS 1459

Query: 168  PSADPPCSLAPAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLA 227
             +  PP +  P+P        T     P   ++     + +P  P         ST  L 
Sbjct: 1460 TTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTT-TPSPPTTTPITPPASTTTLP 1518

Query: 228  SRYTGPYPRNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPP 287
               T P P  +        ++P      P+ PP   T  T  PP   P P PP     PP
Sbjct: 1519 PTTT-PSPPTTTTTTPPPTTTPSPPTTTPITPP---TSTTTLPPTTTPSP-PPTTTTTPP 1573

Query: 288  ACRHPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQ------APYIPPLGLD 341
                P    + +P+ P         T   +    +                P  PP    
Sbjct: 1574 PTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT 1633

Query: 342  AYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQ 401
              P  + P P P+      P  TP  P    P            +   +SP +  TP   
Sbjct: 1634 TLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSP-ITTTPSPP 1692

Query: 402  NNVRAVPQPGAFQRA---CQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHS 458
                  P P     +       P+S     P          T  PS     +       +
Sbjct: 1693 TTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTT 1752

Query: 459  GPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDV 518
              P+     P   TPP   P +              P++P +P+ +    L   +     
Sbjct: 1753 SSPLTTTPLPPSITPPTFSPFS-----------TTTPTTPCVPLCNWTGWLDSGKPNFHK 1801

Query: 519  PAPEATTEPD------------SATAEPDSAPATSEGQDKGCRGTLPA-----QEGPSGS 561
            P  +     D             AT  PD  P    GQ   C  ++        + P G 
Sbjct: 1802 PGGDTELIGDVCGPGWAANISCRATMYPD-VPIGQLGQTVVCDVSVGLICKNEDQKPGGV 1860

Query: 562  KPLRGSLKEEVALDLS--VRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLK 619
             P+   L  E+ +     V +PT   +    +       PT     P +    +  P   
Sbjct: 1861 IPMAFCLNYEINVQCCECVTQPTTMTTTTTEN-------PTPPTTTP-ITTTTTVTPTPT 1912

Query: 620  KIDTEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPA 676
               T+ P    +  TT   P    T   +           + P P P      TPT+ P 
Sbjct: 1913 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPI 1970

Query: 677  PTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAP 729
             T    TPT  P G +     P++ T  +   P+P      +P   P        P+P P
Sbjct: 1971 TTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2028

Query: 730  ARAQAP-----ASARDPAPAPAPVAGPAPAST 756
               Q P      +     P P P     P +T
Sbjct: 2029 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2060



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2054 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2111

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2112 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2169

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 2170 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 2198



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2100 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2157

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2158 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2215

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 2216 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 2244



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2146 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2203

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2204 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2261

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 2262 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 2290



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2192 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2249

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2250 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2307

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 2308 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 2336



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2238 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2295

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2296 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2353

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 2354 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 2382



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2284 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2341

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2342 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2399

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 2400 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 2428



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2330 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2387

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2388 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2445

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 2446 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 2474



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2376 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2433

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2434 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2491

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 2492 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 2520



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2422 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2479

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2480 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2537

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 2538 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 2566



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2468 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2525

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2526 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2583

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 2584 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 2612



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2514 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2571

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2572 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2629

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 2630 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 2658



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2560 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2617

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2618 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2675

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 2676 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 2704



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2606 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2663

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2664 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2721

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 2722 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 2750



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2652 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2709

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2710 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2767

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 2768 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 2796



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2698 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2755

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2756 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2813

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 2814 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 2842



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2744 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2801

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2802 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2859

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 2860 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 2888



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2790 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2847

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2848 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2905

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 2906 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 2934



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2836 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2893

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2894 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2951

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 2952 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 2980



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2882 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2939

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2940 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2997

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 2998 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3026



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2928 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 2985

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 2986 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3043

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3044 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3072



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 2974 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3031

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3032 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3089

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3090 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3118



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3020 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3077

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3078 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3135

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3136 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3164



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3066 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3123

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3124 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3181

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3182 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3210



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3112 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3169

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3170 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3227

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3228 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3256



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3158 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3215

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3216 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3273

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3274 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3302



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3204 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3261

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3262 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3319

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3320 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3348



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3250 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3307

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3308 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3365

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3366 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3394



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3296 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3353

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3354 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3411

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3412 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3440



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3342 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3399

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3400 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3457

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3458 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3486



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3388 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3445

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3446 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3503

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3504 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3532



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3434 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3491

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3492 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3549

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3550 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3578



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3480 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3537

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3538 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3595

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3596 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3624



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3526 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3583

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3584 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3641

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3642 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3670



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3572 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3629

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3630 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3687

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3688 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3716



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3618 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3675

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3676 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3733

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3734 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3762



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3664 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3721

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3722 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3779

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3780 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3808



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3710 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3767

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3768 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3825

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3826 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3854



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3756 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3813

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3814 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3871

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3872 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3900



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3802 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3859

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3860 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3917

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3918 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3946



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3848 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3905

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3906 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3963

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 3964 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 3992



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3894 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3951

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3952 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4009

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 4010 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 4038



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3940 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 3997

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 3998 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4055

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 4056 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 4084



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 3986 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 4043

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 4044 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4101

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 4102 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 4130



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/149 (23%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 4032 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 4089

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARA 732
               TPT  P G +     P++ T  +   P+P      +P   P        P+P P   
Sbjct: 4090 TTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4147

Query: 733  QAP-----ASARDPAPAPAPVAGPAPAST 756
            Q P      +     P P P     P +T
Sbjct: 4148 QTPTTTPITTTTTVTPTPTPTGTQTPTTT 4176



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 25/88 (28%), Positives = 33/88 (37%), Gaps = 13/88 (14%)

Query: 672  TSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPAR 731
            T +P  T P+P PTS             + T      PSPP     +P P   PSP    
Sbjct: 1398 TPSPPTTTPSPPPTS-------------TTTLPPTTTPSPPTTTTTTPPPTTTPSPPITT 1444

Query: 732  AQAPASARDPAPAPAPVAGPAPASTSAP 759
               P     P+P  +    P P +T +P
Sbjct: 1445 TTTPPPTTTPSPPISTTTTPPPTTTPSP 1472



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 63/273 (23%), Positives = 82/273 (30%), Gaps = 46/273 (16%)

Query: 494  PPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLP 553
            PP++ P P   +  +L P       P+P  TT          S P T+         T P
Sbjct: 1401 PPTTTPSPPPTSTTTLPP----TTTPSPPTTTTTTPPPTTTPSPPITTTT-------TPP 1449

Query: 554  AQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVS 613
                PS   P+  +         S   PT   SP   + S     PT     P      S
Sbjct: 1450 PTTTPS--PPISTTTTPPPTTTPS--PPTTTPSPPTTTPS----PPTTTTTTPPPTTTPS 1501

Query: 614  DLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTP-- 671
              P    I   A      P TT + P T   +               P P    P TP  
Sbjct: 1502 P-PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPP---------TTTPSPPTTTPITPPT 1551

Query: 672  --TSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAP 729
              T+ P  T P+P PT+             + T      PSPP     SP      +P P
Sbjct: 1552 STTTLPPTTTPSPPPTT-------------TTTPPPTTTPSPPTTTTPSPPTITTTTPPP 1598

Query: 730  ARAQAPASARDPAPAPAPVAGPAPASTSAPGDS 762
                +P +     P P     P   +   P  S
Sbjct: 1599 TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS 1631



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 32/115 (27%), Positives = 41/115 (35%), Gaps = 27/115 (23%)

Query: 661  PLPAAVVPS---------TPTSAPAP-----TQPAPTPTSGPIGLRILAQQPLSVTCF-- 704
            P P    PS          PT+ P+P     T P PT T  P         P++ T    
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSP---------PITTTTTPP 1449

Query: 705  SLALPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAP 759
                PSPP     +P P   PSP       P +   P+P       P P +T +P
Sbjct: 1450 PTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTT--PSPPTTTTTTPPPTTTPSP 1502



 Score = 37.0 bits (84), Expect = 0.097
 Identities = 34/140 (24%), Positives = 44/140 (31%), Gaps = 13/140 (9%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 4101 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 4158

Query: 680  PAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASAR 739
               TPT  P G +     P++ T      P+P       P      S AP      A   
Sbjct: 4159 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHT---STAPI-----AELT 4210

Query: 740  DPAPAPAPVAGPAPASTSAP 759
               P P         STS+P
Sbjct: 4211 TSNPPPESSTPQTSRSTSSP 4230



 Score = 35.4 bits (80), Expect = 0.28
 Identities = 42/183 (22%), Positives = 58/183 (31%), Gaps = 40/183 (21%)

Query: 623  TEAPGLPGVPVTTDAMPR---TNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ 679
            T+ P    +  TT   P    T   +           + P P P      TPT+ P  T 
Sbjct: 4124 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTT 4181

Query: 680  PAPTPTSGPIGLRI-----LAQQPLSVTCFSLALPS------------------------ 710
               TPT  P G +       +  P++    S   P                         
Sbjct: 4182 TTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTL 4241

Query: 711  PPAVAVASPAPAPAPSPAPARAQ-----APASARDPAPAPAPVAGPAPASTSAPGDSLEQ 765
            PPA+ + S AP   P+ AP         +P  +   +P   P  G    S+SAP  S  Q
Sbjct: 4242 PPAIEMTSTAPPSTPT-APTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQ 4300

Query: 766  HFT 768
              T
Sbjct: 4301 TTT 4303



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 30/120 (25%), Positives = 40/120 (33%), Gaps = 19/120 (15%)

Query: 659  PAPLPAAVVPSTPTSAPAPTQPAPTP---TSGPI--GLRILAQQPLSVTCFSLALPSPPA 713
            P     A +    TS P P    P     TS P+     +L+  P ++   S A PS P 
Sbjct: 4198 PTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPT 4257

Query: 714  VAVA-------SPAPAPAPSPAPARAQAPASARDPAPAPAPVA-------GPAPASTSAP 759
                       SP P+   SP     +   +    AP P+ V         P P   S P
Sbjct: 4258 APTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTP 4317


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 142/589 (24%), Positives = 200/589 (33%), Gaps = 127/589 (21%)

Query: 231 TGPYPRNSKQAMSEGPSSPWTQLAQPL-GPPCQDTGPTHYP-------PPHHPPPHPPQA 282
           +GP P     AM+    +  T++  P   P  +   PT  P         H      P A
Sbjct: 165 SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA 224

Query: 283 LPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQ--------QAAQAPY 334
              P A    ++  S S +    PL     +G  A G                QA + P 
Sbjct: 225 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284

Query: 335 IPPLGLDAYP----YPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGA 390
           + P   DA P      S+PL  PSP   L+    P  P      +L+   A   L L   
Sbjct: 285 VTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATP-LPLAPP 343

Query: 391 SPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKL 450
           SP     PPS   ++ +P P A        P SQ  +    P  +A   ++LPS      
Sbjct: 344 SPS---APPS---LQTLPSPPA-------TPPSQATTSLGSPTLQATH-SFLPS------ 383

Query: 451 QPRLSEHSGPPIVIRDSPVPCTPPAL--PPCARECQSLPQKEDARPPSSP---PMPVIDN 505
                    PP+    +P P  PPAL  PP        P    A PP SP   P P   N
Sbjct: 384 ---------PPLSPLATPPPQAPPALALPPL-----QAPPSPPASPPLSPLATPSPQAPN 429

Query: 506 VFSLAPYRDYLDVPAPEATTEPDSATAEPDSAP-ATSEGQDKGCRGTLPAQEGPS--GSK 562
             ++   +     P       P S  A P  +P AT   Q        P Q  PS   S 
Sbjct: 430 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 489

Query: 563 PLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKID 622
           P+  S             P  +A P  A+  ++ AKP                       
Sbjct: 490 PMSPSAT-----------PPPQAPPPLAAPPLQLAKPPPQAP------------------ 520

Query: 623 TEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAP 682
              P L   P+     P  +F     F             P+A +P +P + P P   AP
Sbjct: 521 ---PALATPPLQALPSPPASFPGQAPFS------------PSASLPMSPLATPPPQ--AP 563

Query: 683 TPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAP----APAPSPAPARAQAPASA 738
              + P+ L++    P S T  +   P  P    +   P    A AP P P  +++P+S 
Sbjct: 564 PVLAAPL-LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 622

Query: 739 RDPAPAPAPVAGPAPASTSAPGDSLEQHFTGLHASLCDAISGSVAHSPP 787
                +   +AG + ++TS P + L  + +G          G  A SPP
Sbjct: 623 L----SGPDLAGHSSSATSTP-EELRGYDSG--------PEGGAAASPP 658



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 164/669 (24%), Positives = 222/669 (33%), Gaps = 110/669 (16%)

Query: 5   RPLRTLGPVMYGKLPRLETDSGLEHSLPHSV-----------GNQDPCTYKGSYFSCPMA 53
           RP  +  P    + PR    S  EHS                G Q P +   S  + P++
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250

Query: 54  GTPKAESEQLASWTPYPPLYSTGMAGPPLQADNLLTNCLFYRSPAEGPEKMQDSSPVELL 113
               A S   A  TP  P + +      LQA          R P   P + +D++P  L 
Sbjct: 251 SP--ARSGPSARGTPRAPAHPSQPKPKGLQA---------LRPPQVTPPR-KDAAPA-LG 297

Query: 114 PFSPQAHSYPGPPLA----APKPVYRNPLCYGLSTCLGEGAVKRPLDVDWTLATGPLLPS 169
           P S    + P P  A    AP  +   P    L+  L   A   PL         P  PS
Sbjct: 298 PLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQL---ATPLPL--------APPSPS 346

Query: 170 ADPPCSLAPAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASR 229
           A P     P+P        T   G P    +  ++ SF P  P             LA+ 
Sbjct: 347 APPSLQTLPSPPATPPSQATTSLGSP----TLQATHSFLPSPPLSP----------LATP 392

Query: 230 YTGPYPRNSKQAMSEGPSSPWTQLAQPLGPPCQDTG---PTHY-PPPHHPPPHPPQALPC 285
                P  +   +   PS P +    PL  P          H    P  PPP PP   P 
Sbjct: 393 PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 452

Query: 286 PPACRHPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPY 345
            P    P    +  P+                  L +P L Q     P  PP+   A P 
Sbjct: 453 SPPASPPVSPSATPPS-------------QAPPSLAAPPL-QVPPSPPASPPMSPSATPP 498

Query: 346 PSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQN--- 402
           P AP P  +P L+L  P  P+     AP  L+ P  +   S   + PG     PS +   
Sbjct: 499 PQAPPPLAAPPLQLAKP-PPQ-----APPALATPPLQALPSPPASFPGQAPFSPSASLPM 552

Query: 403 NVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPI 462
           +  A P P A      PL    P S P  P  +A  +   P        P  S  SGP +
Sbjct: 553 SPLATPPPQAPPVLAAPL-LQVPPSPPASPTLQAPRRPPTPG-------PDTSV-SGPRL 603

Query: 463 VIRDSPVPCTPPALPPCA---------RECQSLPQKEDARPPSSPP------MPVIDNVF 507
            +  +P P  PP+  P +             +    E+ R   S P       P  D   
Sbjct: 604 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 663

Query: 508 SLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGS 567
           +      +   PAP            P   PAT  G   G   T+   EGP  + P  G+
Sbjct: 664 AACHPAAWSRGPAPPLAFRGAPGAPLP-WPPATGPGSADGLC-TIYETEGPESATPAPGA 721

Query: 568 LKEEVALDLSVRKPTAEASPVKASRSVEHAK----PTAAMDVPDVGNMVSDLPGLKKIDT 623
           L    +   S  K  A A    +SRS + A+    P  A+    V +++S    L   + 
Sbjct: 722 LDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEG 781

Query: 624 EAPGLPGVP 632
            A G  G P
Sbjct: 782 AAGGSGGGP 790



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 164/653 (25%), Positives = 217/653 (33%), Gaps = 118/653 (18%)

Query: 117 PQAHSYPGPPLAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWTLATGPLLPSADPPCSL 176
           P   + P PP   P+    +   +  +T     A +RP       A G L   A    S 
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHS-TTEPSPAARRRPS------AGGGLQRPASRSLSS 244

Query: 177 APAPSKGQTLDGTFLRGVP---AEGSSKDSSG--SFSPCQPFLEKYQTIHSTGFLASR-Y 230
           +  P       G   RG P   A  S     G  +  P Q    +     + G L+S   
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 304

Query: 231 TGPYPRNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACR 290
             P P  + Q+ +  P+ P T  +  L   CQ   P    PP    P   Q LP PPA  
Sbjct: 305 ATPSPSAALQSQAP-PTLPATPHSSSL--TCQLATPLPLAPPSPSAPPSLQTLPSPPAT- 360

Query: 291 HPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPL 350
            P  Q + S                    LGSP L+   +  P  PPL   A P P AP 
Sbjct: 361 -PPSQATTS--------------------LGSPTLQATHSFLPS-PPLSPLATPPPQAPP 398

Query: 351 PAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQP 410
               P L+  PP  P  P   +P     P A + L+++        +PP    V+A   P
Sbjct: 399 ALALPPLQA-PPSPPASP-PLSPLATPSPQAPNALAVHLLQAPF--SPPPSPPVQAPFSP 454

Query: 411 GAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVP 470
                     PAS P S    P  +A      PS     LQ   S  + PP+    +P P
Sbjct: 455 ----------PASPPVSPSATPPSQAP-----PSLAAPPLQVPPSPPASPPMSPSATPPP 499

Query: 471 CTPPALPPCARECQSLPQKEDARPPS--SPPMPVIDNVFSL----APYRDYLDVPAPEAT 524
             PP   P A     L +     PP+  +PP+  + +  +     AP+     +P     
Sbjct: 500 QAPP---PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 556

Query: 525 TEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAE 584
           T P  A     +AP            TL A   P    P        + L L      A 
Sbjct: 557 TPPPQAPPVL-AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL------AP 609

Query: 585 ASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPG----LKKIDTEAPGLPGVPVTTDAMPR 640
             P   SRS     P++ +  PD+    S        L+  D+   G        DA   
Sbjct: 610 GPPPPPSRS-----PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA--- 661

Query: 641 TNFHSSVAFMFRKFKILRPA-----PLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRIL- 694
                       +     PA     P P       P  AP P  PA  P S   GL  + 
Sbjct: 662 ------------ELAACHPAAWSRGPAPPLAFRGAP-GAPLPWPPATGPGSAD-GLCTIY 707

Query: 695 -AQQPLSVTCFSLALPSPPAVAVASPAPAPAPS--PAPARAQAPASARDPAPA 744
             + P S T         PA     P P+P  S   A A A A AS+R P  A
Sbjct: 708 ETEGPESAT---------PAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQA 751



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 123/522 (23%), Positives = 168/522 (32%), Gaps = 80/522 (15%)

Query: 256 PLGPPCQDTGPTHYPPPHHPPPH------PPQALPCPPACRHPEKQGSYSPALPLQPLGG 309
           P   P +  G +   P   PP        PP     P     P +    +   PL    G
Sbjct: 75  PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL----G 130

Query: 310 HKGTGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPA-PSPGLKLEPPLT---- 364
            KG    A        R +A +AP    L   A    S P P  PSP +           
Sbjct: 131 QKGLRISAE---ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187

Query: 365 --PRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPA 422
             PR     AP     P          ++     T PS    R     G  QR     PA
Sbjct: 188 GLPRP----APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR-----PA 238

Query: 423 SQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARE 482
           S+  S    P          PS R     PR   H   P            P      R 
Sbjct: 239 SRSLSSSATPLSSPARSG--PSARGT---PRAPAHPSQP-----------KPKGLQALRP 282

Query: 483 CQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSE 542
            Q  P ++DA P   P         S +P    L  P+P A  +  +    P + PAT  
Sbjct: 283 PQVTPPRKDAAPALGP--------LSSSP----LATPSPSAALQSQA----PPTLPATPH 326

Query: 543 GQDKGCRGTLPAQEGPSG--SKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPT 600
                C+   P    P    + P   +L    A   S    +  +  ++A+ S   + P 
Sbjct: 327 SSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL 386

Query: 601 AAMDVPDVGNMVSDLPGLKKIDTEAPGLPGV--PVTTDAMPRTNFHSSVAFMFRKFKILR 658
           + +  P         P L     +AP  P    P++  A P     +++A    +     
Sbjct: 387 SPLATPPP----QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF-S 441

Query: 659 PAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVAS 718
           P P P    P +P ++P  +  A  P+  P  L   A  PL V       PSPPA    S
Sbjct: 442 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL---AAPPLQVP------PSPPASPPMS 492

Query: 719 PAPAPAPSPAPARAQAPAS-ARDPAPAPAPVAGPAPASTSAP 759
           P+  P P   P  A  P   A+ P  AP  +A P   +  +P
Sbjct: 493 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP 534



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 102/441 (23%), Positives = 143/441 (32%), Gaps = 68/441 (15%)

Query: 352 APSPGLKL-EPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQP 410
           A +PGL    PP +PR P    P  L          + GA+  +G  P ++   RA    
Sbjct: 19  ARAPGLLTPRPPGSPRPPPPVTPAALR---------VLGAAGAVGRKPLAE---RAGGIG 66

Query: 411 GAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVP 470
           GA       +P S P + P R A  +      P+ R     P        P     SP P
Sbjct: 67  GA------TIPESAPRAGPTRSAGTSSRN---PASRP----PASGRGERAPPAKNTSPGP 113

Query: 471 CTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSA 530
            + P           L QK       S    V     + AP R  L   A   T+ P   
Sbjct: 114 VSSPGRASGTTRPGPLGQKGLR---ISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 170

Query: 531 TAEPDSAPAT-SEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVK 589
           T  P  A  + + G + G     P+        P  G  K   ++  +    T E SP  
Sbjct: 171 TPSPAMARRSRAAGTEVGLPRPAPSARP---RPPTEGPRK---SVSSASEHSTTEPSPAA 224

Query: 590 ASRSVEHAKPTAA--MDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSV 647
             R      P+A   +  P   ++ S    L       P   G P       R   H S 
Sbjct: 225 RRR------PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP-------RAPAHPS- 270

Query: 648 AFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLA 707
                        P P  +    P     P + A  P  GP+    LA    S    S A
Sbjct: 271 ------------QPKPKGLQALRPPQVTPPRKDA-APALGPLSSSPLATPSPSAALQSQA 317

Query: 708 LPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQHF 767
            P+ PA   +S       +P P    +P++       P+P A P   +T++ G    Q  
Sbjct: 318 PPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQ-- 375

Query: 768 TGLHASLCDAISGSVAHSPPE 788
              H+ L       +A  PP+
Sbjct: 376 -ATHSFLPSPPLSPLATPPPQ 395



 Score = 37.7 bits (86), Expect = 0.057
 Identities = 41/151 (27%), Positives = 58/151 (38%), Gaps = 18/151 (11%)

Query: 653 KFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILA------QQPLSVTCFSL 706
           K K    A  PAA  P   T  P P  P P P   P  LR+L       ++PL+     +
Sbjct: 7   KAKAGAAARTPAARAPGLLTPRP-PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI 65

Query: 707 ALPSPPAVAV-ASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPAS-------TSA 758
              + P  A  A P  +   S     ++ PAS R     PA    P P S       T+ 
Sbjct: 66  GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125

Query: 759 PGDSLEQHFTGLHASLCDAISGSVAHSPPEK 789
           PG   ++   GL  S  + ++   A   P++
Sbjct: 126 PGPLGQK---GLRISAEETVARGKATEAPKR 153



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 35/118 (29%), Positives = 47/118 (39%), Gaps = 17/118 (14%)

Query: 929  DTEAGAVSSSEPTVAR-DEPESLALAQKSPAPKVRKPGRKPPTPGPEKAEAAAGEESCGA 987
            DT      +  P +AR        +    PAP  R    +PPT GP K+ ++A E S   
Sbjct: 163  DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP---RPPTEGPRKSVSSASEHST-T 218

Query: 988  SPTPATSASPP--GPTLKARFRSLLETAWLNGLALPTWGHKSSR--------PDQPSP 1035
             P+PA    P   G   +   RSL  +A    L+ P     S+R        P QP P
Sbjct: 219  EPSPAARRRPSAGGGLQRPASRSLSSSA--TPLSSPARSGPSARGTPRAPAHPSQPKP 274


>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
            sapiens]
          Length = 1188

 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 225/951 (23%), Positives = 302/951 (31%), Gaps = 222/951 (23%)

Query: 246  PSSPWTQLAQPLGPPCQDTGPTH---YPPPHHPPPHPPQAL-PCPPACRHPEKQGSYSPA 301
            P      L  P  PP    GP      PP   P P PP    P PP    P    S +P 
Sbjct: 130  PGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPP 189

Query: 302  LP--LQPLGGHKGTGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAP----SP 355
             P  L+ L            L SP +       P  PPL   A P P  P PAP    SP
Sbjct: 190  PPPVLEALS-------PPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASP 242

Query: 356  ---GLKLEPP----------------------LTPRCPLDFAPQTLSFPYARDDLSLYGA 390
               G +L PP                        PR P +     L  P     L+    
Sbjct: 243  HTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALG-PNPEPHLTF--- 298

Query: 391  SPGLGGTPPSQNNVRAVP----------QPGAFQRACQPLPASQPCSEPVRPAQEA-EEK 439
                   PP+     ++P          + GA ++A   LP   P S  +RPA +   ++
Sbjct: 299  PRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPL--PPSFHIRPASQVYPDR 356

Query: 440  TWLPSCRKE-----KLQPRLSEHSG----------------PPIVIRDSPVPCTPPALP- 477
               P C  E        PRL +                   PP      P P  PPA P 
Sbjct: 357  APEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP 416

Query: 478  -PCARECQSLPQKEDARPPSSPPM-------PVIDNVFSLAPYRDYLDVPAPEATTEPDS 529
             PCA++    P      P SS P        P  +N  S AP  D+ D    E      +
Sbjct: 417  LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPV-DWRDPSQMEKLRNELA 475

Query: 530  A--------------TAEPDSAPATSEGQ------DKGCRGTLPAQEGPSG--SKPLRGS 567
            A                 P  AP + EG+      +K    +LPA++ P G   K L GS
Sbjct: 476  AYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGS 535

Query: 568  LKEEVALDLSVRKPTAEASP-------VKASRSVEHAKPTAAMD---VPDVGNMVSDLPG 617
               E     S+  P+ +  P       V+  R+   A+ ++A +    P +G++    P 
Sbjct: 536  SLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSL-PPKPR 594

Query: 618  L-------------KKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPA-PLP 663
            L             K     A  LP  P +T  +P T+             +L PA P  
Sbjct: 595  LEGGRICENGADDDKLSKPVAKNLP--PQSTTLLPTTSLQPKA--------MLGPAIPPK 644

Query: 664  AAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP 723
            A   P+ P  A       P  T GP         PL  T    + P+ P  A + PA A 
Sbjct: 645  ATPEPAIPPKATLWPATPPKATLGP-------ATPLKAT----SGPTTPLKATSGPAIAS 693

Query: 724  APSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQHFTGLHASLCDAISGSVA 783
              +  P       + +D  PA  P   PA    S P  +  +        L    + S A
Sbjct: 694  TATTLPTTTSQLMAEKDSGPAGQP-EKPASQEVSTPSQARGEGSPSEATRLPTQGARSSA 752

Query: 784  HSPPEKLREWLETAGPWGQAAWQDCQGVQGLLAKLLSQLQRFDRTHRCPFPHVVRAGAI- 842
              PP+          P G        G    L K         R      P + R GA  
Sbjct: 753  AFPPK--------TSPGG--------GEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAG 796

Query: 843  -FVPIHLVKERLFPRLPPASVDHVLQEHRVELRPT-TLSEERALRELALPGCTSRMLKLL 900
               P+ + +    P  PPAS            +PT  L       E+   G  S M  LL
Sbjct: 797  PGEPVEVKEPPGLPAKPPASA-----------QPTDELLRHPVTGEVVERG--SPMALLL 843

Query: 901  ALRQLPDIYPDLLGLQWRDCVRRQLGDFDTEAGAVSSS-------------EPTVARDEP 947
            A RQ       +     R  +   L D   +A A S S              P + ++  
Sbjct: 844  AARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAE 903

Query: 948  ESLALAQKSPAPKVRKPGR--------------KPPTPGPEKAEAAAGEESCGASPTPAT 993
            +   L  + P     + GR              KP    P   E  A        P P +
Sbjct: 904  KDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKS 963

Query: 994  SASPPGPTLKARFRSLLETAWLNGLALPTWGHKSSRPDQPSPCPQLLDSQS 1044
             +SPP P+ K       E    N   +P     S+ P+ P+P  Q L  QS
Sbjct: 964  FSSPPSPSNKRE----EEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQS 1010



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 159/676 (23%), Positives = 221/676 (32%), Gaps = 101/676 (14%)

Query: 107 SSPVELLPFSPQAHSYPGPPLAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWTLATGPL 166
           S P    P  P     P PP  AP P    P+   LS      +   P   D+     PL
Sbjct: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPP---PVLEALSPPHTLSSPSIPTPPDFIPPAPPL 221

Query: 167 LPSADPPCSL-APAPSKGQTLDGTFLRGVPAEGSSK-DSSGSFSPCQPFLEKYQTIHSTG 224
              A PP  + APAP    +      R  P  G +K  S  + +  Q    +     S  
Sbjct: 222 AFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPA 281

Query: 225 FLASRYTGPYPR---NSKQAMSEGPSSPWTQLAQPLGP----PCQDTGPTHYPPPHHPPP 277
                  GP P       ++    P +P    + P+      P ++ G T   P   P P
Sbjct: 282 EPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLP 341

Query: 278 HP----PQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQAP 333
                 P +   P     P+  G      P  P  G   +  QA         ++A   P
Sbjct: 342 PSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQS--QAD--------ERAGTPP 391

Query: 334 YIPPLGLDAYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPG 393
             PPL     P P+ PLP P+P L   PP  P  P     Q  + P A    +   +SP 
Sbjct: 392 PAPPL-----PPPAPPLPPPAPPL---PPAAPPLP---CAQKAAHPPAGFTKTPKSSSPA 440

Query: 394 LGG--TPPS-QNNVRAVP----QPGAFQRACQPLPASQPCSEPV-RPAQEAEEKTWLPSC 445
           L     PPS +N   + P     P   ++    L A    S    R        T  P  
Sbjct: 441 LKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQS 500

Query: 446 RKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDN 505
           ++ K  PRL E       +   P   TPP +P  +    SL + E A   + P +  I  
Sbjct: 501 KEGKKGPRLPEKE----TLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQ 556

Query: 506 VFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLR 565
                      D P P      +   A   SA   +E + K   G+LP +    G     
Sbjct: 557 -----------DSPTPSVRQIRNELEARLSSA---AEKEAKPSIGSLPPKPRLEG----- 597

Query: 566 GSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEA 625
           G + E  A D  + KP A+  P           P +   +P        + G   I  +A
Sbjct: 598 GRICENGADDDKLSKPVAKNLP-----------PQSTTLLPTTSLQPKAMLG-PAIPPKA 645

Query: 626 PGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPA-PTQPAPTP 684
              P +P      P T                   P  A + P+TP  A + PT P    
Sbjct: 646 TPEPAIPPKATLWPAT-------------------PPKATLGPATPLKATSGPTTPLKA- 685

Query: 685 TSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAPA 744
           TSGP         P + +       S PA     PA     +P+ AR +   S     P 
Sbjct: 686 TSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPT 745

Query: 745 PAPVAGPAPASTSAPG 760
               +  A    ++PG
Sbjct: 746 QGARSSAAFPPKTSPG 761


>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
            sapiens]
          Length = 1188

 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 225/951 (23%), Positives = 302/951 (31%), Gaps = 222/951 (23%)

Query: 246  PSSPWTQLAQPLGPPCQDTGPTH---YPPPHHPPPHPPQAL-PCPPACRHPEKQGSYSPA 301
            P      L  P  PP    GP      PP   P P PP    P PP    P    S +P 
Sbjct: 130  PGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPP 189

Query: 302  LP--LQPLGGHKGTGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAP----SP 355
             P  L+ L            L SP +       P  PPL   A P P  P PAP    SP
Sbjct: 190  PPPVLEALS-------PPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASP 242

Query: 356  ---GLKLEPP----------------------LTPRCPLDFAPQTLSFPYARDDLSLYGA 390
               G +L PP                        PR P +     L  P     L+    
Sbjct: 243  HTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALG-PNPEPHLTF--- 298

Query: 391  SPGLGGTPPSQNNVRAVP----------QPGAFQRACQPLPASQPCSEPVRPAQEA-EEK 439
                   PP+     ++P          + GA ++A   LP   P S  +RPA +   ++
Sbjct: 299  PRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPL--PPSFHIRPASQVYPDR 356

Query: 440  TWLPSCRKE-----KLQPRLSEHSG----------------PPIVIRDSPVPCTPPALP- 477
               P C  E        PRL +                   PP      P P  PPA P 
Sbjct: 357  APEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP 416

Query: 478  -PCARECQSLPQKEDARPPSSPPM-------PVIDNVFSLAPYRDYLDVPAPEATTEPDS 529
             PCA++    P      P SS P        P  +N  S AP  D+ D    E      +
Sbjct: 417  LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPV-DWRDPSQMEKLRNELA 475

Query: 530  A--------------TAEPDSAPATSEGQ------DKGCRGTLPAQEGPSG--SKPLRGS 567
            A                 P  AP + EG+      +K    +LPA++ P G   K L GS
Sbjct: 476  AYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGS 535

Query: 568  LKEEVALDLSVRKPTAEASP-------VKASRSVEHAKPTAAMD---VPDVGNMVSDLPG 617
               E     S+  P+ +  P       V+  R+   A+ ++A +    P +G++    P 
Sbjct: 536  SLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSL-PPKPR 594

Query: 618  L-------------KKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPA-PLP 663
            L             K     A  LP  P +T  +P T+             +L PA P  
Sbjct: 595  LEGGRICENGADDDKLSKPVAKNLP--PQSTTLLPTTSLQPKA--------MLGPAIPPK 644

Query: 664  AAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP 723
            A   P+ P  A       P  T GP         PL  T    + P+ P  A + PA A 
Sbjct: 645  ATPEPAIPPKATLWPATPPKATLGP-------ATPLKAT----SGPTTPLKATSGPAIAS 693

Query: 724  APSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQHFTGLHASLCDAISGSVA 783
              +  P       + +D  PA  P   PA    S P  +  +        L    + S A
Sbjct: 694  TATTLPTTTSQLMAEKDSGPAGQP-EKPASQEVSTPSQARGEGSPSEATRLPTQGARSSA 752

Query: 784  HSPPEKLREWLETAGPWGQAAWQDCQGVQGLLAKLLSQLQRFDRTHRCPFPHVVRAGAI- 842
              PP+          P G        G    L K         R      P + R GA  
Sbjct: 753  AFPPK--------TSPGG--------GEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAG 796

Query: 843  -FVPIHLVKERLFPRLPPASVDHVLQEHRVELRPT-TLSEERALRELALPGCTSRMLKLL 900
               P+ + +    P  PPAS            +PT  L       E+   G  S M  LL
Sbjct: 797  PGEPVEVKEPPGLPAKPPASA-----------QPTDELLRHPVTGEVVERG--SPMALLL 843

Query: 901  ALRQLPDIYPDLLGLQWRDCVRRQLGDFDTEAGAVSSS-------------EPTVARDEP 947
            A RQ       +     R  +   L D   +A A S S              P + ++  
Sbjct: 844  AARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAE 903

Query: 948  ESLALAQKSPAPKVRKPGR--------------KPPTPGPEKAEAAAGEESCGASPTPAT 993
            +   L  + P     + GR              KP    P   E  A        P P +
Sbjct: 904  KDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKS 963

Query: 994  SASPPGPTLKARFRSLLETAWLNGLALPTWGHKSSRPDQPSPCPQLLDSQS 1044
             +SPP P+ K       E    N   +P     S+ P+ P+P  Q L  QS
Sbjct: 964  FSSPPSPSNKRE----EEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQS 1010



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 159/676 (23%), Positives = 221/676 (32%), Gaps = 101/676 (14%)

Query: 107 SSPVELLPFSPQAHSYPGPPLAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWTLATGPL 166
           S P    P  P     P PP  AP P    P+   LS      +   P   D+     PL
Sbjct: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPP---PVLEALSPPHTLSSPSIPTPPDFIPPAPPL 221

Query: 167 LPSADPPCSL-APAPSKGQTLDGTFLRGVPAEGSSK-DSSGSFSPCQPFLEKYQTIHSTG 224
              A PP  + APAP    +      R  P  G +K  S  + +  Q    +     S  
Sbjct: 222 AFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPA 281

Query: 225 FLASRYTGPYPR---NSKQAMSEGPSSPWTQLAQPLGP----PCQDTGPTHYPPPHHPPP 277
                  GP P       ++    P +P    + P+      P ++ G T   P   P P
Sbjct: 282 EPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLP 341

Query: 278 HP----PQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQAP 333
                 P +   P     P+  G      P  P  G   +  QA         ++A   P
Sbjct: 342 PSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQS--QAD--------ERAGTPP 391

Query: 334 YIPPLGLDAYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPG 393
             PPL     P P+ PLP P+P L   PP  P  P     Q  + P A    +   +SP 
Sbjct: 392 PAPPL-----PPPAPPLPPPAPPL---PPAAPPLP---CAQKAAHPPAGFTKTPKSSSPA 440

Query: 394 LGG--TPPS-QNNVRAVP----QPGAFQRACQPLPASQPCSEPV-RPAQEAEEKTWLPSC 445
           L     PPS +N   + P     P   ++    L A    S    R        T  P  
Sbjct: 441 LKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQS 500

Query: 446 RKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDN 505
           ++ K  PRL E       +   P   TPP +P  +    SL + E A   + P +  I  
Sbjct: 501 KEGKKGPRLPEKE----TLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQ 556

Query: 506 VFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLR 565
                      D P P      +   A   SA   +E + K   G+LP +    G     
Sbjct: 557 -----------DSPTPSVRQIRNELEARLSSA---AEKEAKPSIGSLPPKPRLEG----- 597

Query: 566 GSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEA 625
           G + E  A D  + KP A+  P           P +   +P        + G   I  +A
Sbjct: 598 GRICENGADDDKLSKPVAKNLP-----------PQSTTLLPTTSLQPKAMLG-PAIPPKA 645

Query: 626 PGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPA-PTQPAPTP 684
              P +P      P T                   P  A + P+TP  A + PT P    
Sbjct: 646 TPEPAIPPKATLWPAT-------------------PPKATLGPATPLKATSGPTTPLKA- 685

Query: 685 TSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAPA 744
           TSGP         P + +       S PA     PA     +P+ AR +   S     P 
Sbjct: 686 TSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPT 745

Query: 745 PAPVAGPAPASTSAPG 760
               +  A    ++PG
Sbjct: 746 QGARSSAAFPPKTSPG 761


>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens]
          Length = 1188

 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 225/951 (23%), Positives = 302/951 (31%), Gaps = 222/951 (23%)

Query: 246  PSSPWTQLAQPLGPPCQDTGPTH---YPPPHHPPPHPPQAL-PCPPACRHPEKQGSYSPA 301
            P      L  P  PP    GP      PP   P P PP    P PP    P    S +P 
Sbjct: 130  PGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPP 189

Query: 302  LP--LQPLGGHKGTGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAP----SP 355
             P  L+ L            L SP +       P  PPL   A P P  P PAP    SP
Sbjct: 190  PPPVLEALS-------PPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASP 242

Query: 356  ---GLKLEPP----------------------LTPRCPLDFAPQTLSFPYARDDLSLYGA 390
               G +L PP                        PR P +     L  P     L+    
Sbjct: 243  HTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALG-PNPEPHLTF--- 298

Query: 391  SPGLGGTPPSQNNVRAVP----------QPGAFQRACQPLPASQPCSEPVRPAQEA-EEK 439
                   PP+     ++P          + GA ++A   LP   P S  +RPA +   ++
Sbjct: 299  PRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPL--PPSFHIRPASQVYPDR 356

Query: 440  TWLPSCRKE-----KLQPRLSEHSG----------------PPIVIRDSPVPCTPPALP- 477
               P C  E        PRL +                   PP      P P  PPA P 
Sbjct: 357  APEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP 416

Query: 478  -PCARECQSLPQKEDARPPSSPPM-------PVIDNVFSLAPYRDYLDVPAPEATTEPDS 529
             PCA++    P      P SS P        P  +N  S AP  D+ D    E      +
Sbjct: 417  LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPV-DWRDPSQMEKLRNELA 475

Query: 530  A--------------TAEPDSAPATSEGQ------DKGCRGTLPAQEGPSG--SKPLRGS 567
            A                 P  AP + EG+      +K    +LPA++ P G   K L GS
Sbjct: 476  AYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGS 535

Query: 568  LKEEVALDLSVRKPTAEASP-------VKASRSVEHAKPTAAMD---VPDVGNMVSDLPG 617
               E     S+  P+ +  P       V+  R+   A+ ++A +    P +G++    P 
Sbjct: 536  SLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSL-PPKPR 594

Query: 618  L-------------KKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPA-PLP 663
            L             K     A  LP  P +T  +P T+             +L PA P  
Sbjct: 595  LEGGRICENGADDDKLSKPVAKNLP--PQSTTLLPTTSLQPKA--------MLGPAIPPK 644

Query: 664  AAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAP 723
            A   P+ P  A       P  T GP         PL  T    + P+ P  A + PA A 
Sbjct: 645  ATPEPAIPPKATLWPATPPKATLGP-------ATPLKAT----SGPTTPLKATSGPAIAS 693

Query: 724  APSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQHFTGLHASLCDAISGSVA 783
              +  P       + +D  PA  P   PA    S P  +  +        L    + S A
Sbjct: 694  TATTLPTTTSQLMAEKDSGPAGQP-EKPASQEVSTPSQARGEGSPSEATRLPTQGARSSA 752

Query: 784  HSPPEKLREWLETAGPWGQAAWQDCQGVQGLLAKLLSQLQRFDRTHRCPFPHVVRAGAI- 842
              PP+          P G        G    L K         R      P + R GA  
Sbjct: 753  AFPPK--------TSPGG--------GEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAG 796

Query: 843  -FVPIHLVKERLFPRLPPASVDHVLQEHRVELRPT-TLSEERALRELALPGCTSRMLKLL 900
               P+ + +    P  PPAS            +PT  L       E+   G  S M  LL
Sbjct: 797  PGEPVEVKEPPGLPAKPPASA-----------QPTDELLRHPVTGEVVERG--SPMALLL 843

Query: 901  ALRQLPDIYPDLLGLQWRDCVRRQLGDFDTEAGAVSSS-------------EPTVARDEP 947
            A RQ       +     R  +   L D   +A A S S              P + ++  
Sbjct: 844  AARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAE 903

Query: 948  ESLALAQKSPAPKVRKPGR--------------KPPTPGPEKAEAAAGEESCGASPTPAT 993
            +   L  + P     + GR              KP    P   E  A        P P +
Sbjct: 904  KDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKS 963

Query: 994  SASPPGPTLKARFRSLLETAWLNGLALPTWGHKSSRPDQPSPCPQLLDSQS 1044
             +SPP P+ K       E    N   +P     S+ P+ P+P  Q L  QS
Sbjct: 964  FSSPPSPSNKRE----EEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQS 1010



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 159/676 (23%), Positives = 221/676 (32%), Gaps = 101/676 (14%)

Query: 107 SSPVELLPFSPQAHSYPGPPLAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWTLATGPL 166
           S P    P  P     P PP  AP P    P+   LS      +   P   D+     PL
Sbjct: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPP---PVLEALSPPHTLSSPSIPTPPDFIPPAPPL 221

Query: 167 LPSADPPCSL-APAPSKGQTLDGTFLRGVPAEGSSK-DSSGSFSPCQPFLEKYQTIHSTG 224
              A PP  + APAP    +      R  P  G +K  S  + +  Q    +     S  
Sbjct: 222 AFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPA 281

Query: 225 FLASRYTGPYPR---NSKQAMSEGPSSPWTQLAQPLGP----PCQDTGPTHYPPPHHPPP 277
                  GP P       ++    P +P    + P+      P ++ G T   P   P P
Sbjct: 282 EPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLP 341

Query: 278 HP----PQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQAP 333
                 P +   P     P+  G      P  P  G   +  QA         ++A   P
Sbjct: 342 PSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQS--QAD--------ERAGTPP 391

Query: 334 YIPPLGLDAYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPG 393
             PPL     P P+ PLP P+P L   PP  P  P     Q  + P A    +   +SP 
Sbjct: 392 PAPPL-----PPPAPPLPPPAPPL---PPAAPPLP---CAQKAAHPPAGFTKTPKSSSPA 440

Query: 394 LGG--TPPS-QNNVRAVP----QPGAFQRACQPLPASQPCSEPV-RPAQEAEEKTWLPSC 445
           L     PPS +N   + P     P   ++    L A    S    R        T  P  
Sbjct: 441 LKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQS 500

Query: 446 RKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDN 505
           ++ K  PRL E       +   P   TPP +P  +    SL + E A   + P +  I  
Sbjct: 501 KEGKKGPRLPEKE----TLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQ 556

Query: 506 VFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLR 565
                      D P P      +   A   SA   +E + K   G+LP +    G     
Sbjct: 557 -----------DSPTPSVRQIRNELEARLSSA---AEKEAKPSIGSLPPKPRLEG----- 597

Query: 566 GSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEA 625
           G + E  A D  + KP A+  P           P +   +P        + G   I  +A
Sbjct: 598 GRICENGADDDKLSKPVAKNLP-----------PQSTTLLPTTSLQPKAMLG-PAIPPKA 645

Query: 626 PGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPA-PTQPAPTP 684
              P +P      P T                   P  A + P+TP  A + PT P    
Sbjct: 646 TPEPAIPPKATLWPAT-------------------PPKATLGPATPLKATSGPTTPLKA- 685

Query: 685 TSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAPA 744
           TSGP         P + +       S PA     PA     +P+ AR +   S     P 
Sbjct: 686 TSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPT 745

Query: 745 PAPVAGPAPASTSAPG 760
               +  A    ++PG
Sbjct: 746 QGARSSAAFPPKTSPG 761


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 70/220 (31%), Positives = 87/220 (39%), Gaps = 41/220 (18%)

Query: 558  PSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPG 617
            P  S PL  S    V    S   P A  +PV AS S      T A             P 
Sbjct: 1748 PLASAPLPPSTSASVPASTSAPLP-ATLTPVPASTSAPVPASTLA-------------PV 1793

Query: 618  LKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPST--PTSAP 675
            L       P  P  PV+  A    +  +SV           PA   AA + S+  P SAP
Sbjct: 1794 LASTSAPVPASPLAPVSASA----SVSASV-----------PASTSAAAITSSSAPASAP 1838

Query: 676  APTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPA---------PAPS 726
            APT P     S P  + ILA   + +   +LA  S P  A A+ +PA         PA +
Sbjct: 1839 APT-PILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASA 1897

Query: 727  PAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQH 766
            P  +   APASA  PAPAP PV+ P PA  +      + H
Sbjct: 1898 PTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTH 1937



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 81/332 (24%), Positives = 110/332 (33%), Gaps = 69/332 (20%)

Query: 450  LQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPS-SPPMPVIDNVFS 508
            +Q   S  S PP+     P P T  ++P  A     LP      P S S P+P      +
Sbjct: 1737 IQQAQSSASVPPLASAPLP-PSTSASVP--ASTSAPLPATLTPVPASTSAPVPAS----T 1789

Query: 509  LAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSL 568
            LAP       P P +   P SA+A   ++   S         + PA      S P    +
Sbjct: 1790 LAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPA------SAPAPTPI 1843

Query: 569  KEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGL 628
               V+   SV    + + P+ AS     + PT A                      A   
Sbjct: 1844 LASVSTPASVTILASASIPILASALASTSAPTPA---------------------PAASS 1882

Query: 629  PGVPV-TTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSG 687
            P  PV T   +P +   +SV         L PA   A     TP SAP P    P P   
Sbjct: 1883 PAAPVITAPTIPASAPTASVP--------LAPASASAPAPAPTPVSAPNPAP--PAPAQT 1932

Query: 688  PIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQA------------- 734
                    Q PL  T  S   P PP++ + S A  P  +   A  ++             
Sbjct: 1933 QAQTHKPVQNPLQTTSQSSKQP-PPSIRLPS-AQTPNGTDYVASGKSIQTPQSHGTLTAE 1990

Query: 735  --------PASARDPAPAPAPVAGPAPASTSA 758
                    PA   D +    P++ P P S SA
Sbjct: 1991 LWDNKVAPPAVLNDISKKLGPISPPQPPSVSA 2022



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 2/96 (2%)

Query: 669  STPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPA 728
            S+ +  P  + P P  TS  +     A  P ++T    +  +P   +  +P  A   +P 
Sbjct: 1742 SSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPV 1801

Query: 729  PARAQAP--ASARDPAPAPAPVAGPAPASTSAPGDS 762
            PA   AP  ASA   A  PA  +  A  S+SAP  +
Sbjct: 1802 PASPLAPVSASASVSASVPASTSAAAITSSSAPASA 1837



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 64/254 (25%), Positives = 86/254 (33%), Gaps = 41/254 (16%)

Query: 327  QQAAQAPYIPPLGLDAYP---------YPSAPLPA---PSPGLKLEPPLTPRCPLDFAPQ 374
            QQA  +  +PPL     P           SAPLPA   P P     P   P   L     
Sbjct: 1738 QQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAP--VPASTLAPVLA 1795

Query: 375  TLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQ 434
            + S P     L+   AS  +  + P+  +  A+    A        PAS P   P+  + 
Sbjct: 1796 STSAPVPASPLAPVSASASVSASVPASTSAAAITSSSA--------PASAPAPTPILASV 1847

Query: 435  EAEEK-TWLPSCRKEKLQPRLSEHSGP-PIVIRDSPVP--CTPPALPPCARECQSLPQKE 490
                  T L S     L   L+  S P P     SP     T P +P  A          
Sbjct: 1848 STPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPA 1907

Query: 491  DARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRG 550
             A  P+  P PV       AP       PAP A  +  + T +P   P  +  Q      
Sbjct: 1908 SASAPAPAPTPV------SAPN------PAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPP 1955

Query: 551  ---TLPAQEGPSGS 561
                LP+ + P+G+
Sbjct: 1956 PSIRLPSAQTPNGT 1969


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 71.2 bits (173), Expect = 5e-12
 Identities = 185/772 (23%), Positives = 249/772 (32%), Gaps = 189/772 (24%)

Query: 96   SPAEGPEKMQDSSPVELLPFSPQAHSYPGPPLAAPKPVYRNPLCYGLSTCLGEGAVKRPL 155
            SP   P +    SP+E  P SP   S P P L    P+   P    LS    E  +  P 
Sbjct: 501  SPLSPPPESSPFSPLEESPLSPPEESPPSPALET--PLSPPPEASPLSPPFEESPLSPPP 558

Query: 156  DVDWTLATGPLLPSADPPCSLAPAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLE 215
            +          LP++ PP +   +P              P E S        SP  P  E
Sbjct: 559  EE---------LPTSPPPEASRLSP--------------PPEESPMSPPPEESPMSPPPE 595

Query: 216  KYQTIHSTGFLASRYTGPYPRNS-KQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPP--- 271
                       ASR   P+  +       E P SP  + A  L PP +D+ P   PP   
Sbjct: 596  -----------ASRLFPPFEESPLSPPPEESPLSPPPE-ASRLSPPPEDS-PMSPPPEES 642

Query: 272  PHHPPPHPPQALPCPPACR--HPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQQA 329
            P  PPP   +  P P   R   P ++   SP     P         +A  L  P      
Sbjct: 643  PMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPP----EASRLSPP-----P 693

Query: 330  AQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEP-PLTPRCPLDFAPQTLSFPYARDDLSLY 388
              +P  PP      P  S   P P   L   P   +P  PL   PQ          L   
Sbjct: 694  EDSPTSPP------PEDSPASPPPEDSLMSLPLEESPLLPLPEEPQ----------LCPR 737

Query: 389  GASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQP-----CSEPVRP--AQEAEEKTW 441
               P L   P   +      +P    +A +P  + QP     C+ P  P  + +AE    
Sbjct: 738  SEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHL 797

Query: 442  LPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMP 501
             P   +  L P+  E   P +    SPVP   P L P   E    PQ E+   P   P P
Sbjct: 798  SPQPEELHLSPQTEE---PHL----SPVP-EEPCLSPQPEESHLSPQSEE---PCLSPRP 846

Query: 502  VIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSE---GQDKGCRGTLPAQEGP 558
               +   L+P     ++  P  +  P+    EP   PA  E       G     P    P
Sbjct: 847  EESH---LSP-----ELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEP 898

Query: 559  SGSKPLR---GSLKEEVAL------DLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVG 609
            + S+P       L EE+ L       LS +    +  P   S  +  A P A   +  +G
Sbjct: 899  ALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPA---LSPLG 955

Query: 610  NMVSDLPGLKKIDTEAP-GLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVP 668
             +          D E+P   P +       P  N                P P+P  ++P
Sbjct: 956  ELEYPFGAKGDSDPESPLAAPILETPISPPPEAN-------------CTDPEPVPPMILP 1002

Query: 669  STPTSAPAPTQP----------------------APTPTSGPIGLRILAQQPLS------ 700
             +P S   P  P                      +P     P  L +    PLS      
Sbjct: 1003 PSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVV 1062

Query: 701  ----------VTCFSLALPSPPAV--AVASPAPA-------PAPSPAPARAQAPASARDP 741
                      +    ++ P  PA+  +  SP P+       PAPSPAPA         D 
Sbjct: 1063 GVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDT 1122

Query: 742  AP---APAPVAGPAPASTSAPGDSLEQHFTGLHASLCDAISGSVAHSPPEKL 790
            AP     AP + P P  T  PG            SL   + GS     PE+L
Sbjct: 1123 APLDGIDAPGSQPEPGQT--PG------------SLASELKGSPVLLDPEEL 1160



 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 138/542 (25%), Positives = 181/542 (33%), Gaps = 58/542 (10%)

Query: 256 PLGPPCQDTGPTHYPPPHH---PPPHPPQALPCPPACR--HPEKQGSYSPALPLQPLGGH 310
           PL PP +++ PT  PP      PPP    A P P A     P ++   SP     PL   
Sbjct: 448 PLSPPPEES-PTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPP 506

Query: 311 KGTGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEPPLTPRCPLD 370
             +        SP+      ++P  PP      P    PL  P     L PP     PL 
Sbjct: 507 PES--------SPF--SPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFE-ESPLS 555

Query: 371 FAPQTL--SFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSE 428
             P+ L  S P     LS       +   PP ++ +   P+        +  P S P  E
Sbjct: 556 PPPEELPTSPPPEASRLSPPPEESPMS-PPPEESPMSPPPEASRLFPPFEESPLSPPPEE 614

Query: 429 -PVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVP----CTPP----ALPPC 479
            P+ P  EA   +  P        P  S  S PP V R SP+P     +PP     L P 
Sbjct: 615 SPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP 674

Query: 480 ARECQSLPQKEDAR---PPSSPPM--PVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEP 534
             E  + P  E +R   PP   P   P  D+  S  P    + +P  E+   P     EP
Sbjct: 675 PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP--LPEEP 732

Query: 535 DSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSV 594
              P  SEG     R   P    P   +P      EE  L     +P   A P +     
Sbjct: 733 QLCP-RSEGPHLSPRPEEP-HLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEE----- 785

Query: 595 EHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKF 654
            H  P A  + P +     +L       TE P L  VP      P+     S      + 
Sbjct: 786 PHLSPQA--EGPHLSPQPEELH--LSPQTEEPHLSPVPEEPCLSPQP--EESHLSPQSEE 839

Query: 655 KILRPAPLPAAVVP--STPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPP 712
             L P P  + + P    P  +P P +P   P   P    +    P      S  L  P 
Sbjct: 840 PCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPA 899

Query: 713 AVAVASPAPAPAPSPAPARAQAPASAR------DPAPAP-APVAGPAPASTSAPGDSLEQ 765
                 P  +P P   P       S        DP P P +P+   A     +P   LE 
Sbjct: 900 LSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEY 959

Query: 766 HF 767
            F
Sbjct: 960 PF 961



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 104/432 (24%), Positives = 140/432 (32%), Gaps = 71/432 (16%)

Query: 364 TPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVP--QPGAFQRACQPLP 421
           TP C     P+    P    D +LY A  G     P   +V ++   +PG  Q   +PL 
Sbjct: 366 TPVCSRFSPPEPGDTPTDEPD-ALYVACQG----QPKGGHVTSMQPKEPGPLQCEAKPLG 420

Query: 422 ASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEH--SGPPIVIRDSPVPCTPPALP-- 477
            +    EP   A   EE   LP   +  L P   E   S PP   R SP P   PA P  
Sbjct: 421 KAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLP 480

Query: 478 -------PCARECQSLPQKED-------------------ARPPSSPPMPVIDNVFSLAP 511
                  P      S P +E                    + P  SPP P ++   S  P
Sbjct: 481 EALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPP 540

Query: 512 YRDYLDVPAPEATTEP---DSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSL 568
               L  P  E+   P   +  T+ P  A   S   ++      P +E P    P    L
Sbjct: 541 EASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSP-PPEESPMSPPPEASRL 599

Query: 569 KEEVALDLSVRKPTAEASPVKASRSVEHAKP---TAAMDVPDVGNMVSDLPGLKKIDTEA 625
                 + S   P  E SP+          P    + M  P   + +S  P       E 
Sbjct: 600 FP--PFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPP-------EV 650

Query: 626 PGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVP---STPTSAPAPTQPAP 682
             L  +PV +   P      S      +     P P  + + P    +PTS P    PA 
Sbjct: 651 SRLSPLPVVSRLSPPP--EESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPAS 708

Query: 683 TPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAP-------SPAPARAQAP 735
            P    +    L + PL      L LP  P +   S  P  +P       SP P      
Sbjct: 709 PPPEDSLMSLPLEESPL------LPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLS 762

Query: 736 ASARDPAPAPAP 747
             A +P  +P P
Sbjct: 763 PQAEEPHLSPQP 774



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 108/438 (24%), Positives = 138/438 (31%), Gaps = 123/438 (28%)

Query: 113  LPFSPQAHSYPGPPLAAPKPVYRNPLC-YGLSTCLGEGAVKRPLDVDWTLATGPLLPSAD 171
            +P  P A   P PP AAP     +P    GLST   +G +K                   
Sbjct: 2106 IPPQPGALGSP-PPAAAPTIFIGSPTTPAGLSTS-ADGFLK------------------- 2144

Query: 172  PPCSLAPAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYT 231
            PP    P P     L       VPA+  S+D  G  +P  P   ++ T   T        
Sbjct: 2145 PPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFG-LAPAYPLEPRFPTAPPT-------Y 2196

Query: 232  GPYPRNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPP----HHPPPHPPQALPCPP 287
             PYP     + +  P+ P   L     P     G  H  PP    H P    P   P  P
Sbjct: 2197 PPYP-----SPTGAPAQP-PMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCP 2250

Query: 288  ACRH---PEKQG-----SYSPALPLQPLG-GHKGTGYQAGGLGSPYLRQQAAQAPYIPPL 338
            +  +   PE  G     +  P L   P G   K    +   LG        A +P   P 
Sbjct: 2251 SLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELG--------ASSPSYGPP 2302

Query: 339  GLDAYPYPSAPLPAPSPGLK----LEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGL 394
             L     PS+        LK     + PLTPR      PQ                SPGL
Sbjct: 2303 NLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRAS-QVEPQ----------------SPGL 2345

Query: 395  GGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRL 454
            G  P         P P    +A  P P S P  +  RP    +                 
Sbjct: 2346 GLRPQE-------PPPA---QALAPSPPSHP--DIFRPGSYTDP---------------- 2377

Query: 455  SEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSP-----------PMPVI 503
              ++ PP+  R  P    PP    CA   +SLP    +R P+SP           P P+ 
Sbjct: 2378 --YAQPPLTPRPQP----PPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLS 2431

Query: 504  DNVFSLAPYRDYLDVPAP 521
               F  +P       P P
Sbjct: 2432 AEAFCPSPVTPRFQSPDP 2449



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 154/697 (22%), Positives = 213/697 (30%), Gaps = 126/697 (18%)

Query: 101  PEKMQDSSPVELLPFSPQAHSYPGPPLAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWT 160
            P +   S P   +P SPQ+ S    PL  P+P+     C           V         
Sbjct: 2399 PPRSLPSDPFSRVPASPQSQSSSQSPL-TPRPLSAEAFC--------PSPVTPRFQSPDP 2449

Query: 161  LATGPLLPSADPPCSLAPAPSKGQTLDGTFLRGVPAEGSSKDSSGSFS---PCQPFLEKY 217
             +  P  P +  P +    P + Q  +  F  G  A  S    +G F    P  P  E +
Sbjct: 2450 YSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSL--GAGGFPAALPAGPAGELH 2507

Query: 218  QTIHS---TGFLASRYTGPYPRNSKQAMSEGPSSPWTQLAQP-LGPPCQDTGPTHYPPPH 273
              + S     F+ S  TG +           P +    + +P L PP    G    PPPH
Sbjct: 2508 AKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQA----VGEPSLKPPVPQPG---LPPPH 2560

Query: 274  HPPPH--PPQALPCPPACRHPEKQGSYSPA-LPLQPLGGHKGTGYQAGGLGSPYLRQQAA 330
                H  P   L  P +  +    G++ P+  PL P  G  G  Y    L  P +     
Sbjct: 2561 GINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSV----- 2615

Query: 331  QAPYIPPLGLDAYPYPSAPLPAPSPGLKLEPPLT--------PRCPLDFAPQTLSFPYAR 382
                +PP      P P   LP  S G      +T        P   +  +  T   P  +
Sbjct: 2616 ----LPP------PAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQ 2665

Query: 383  DDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWL 442
            D        PG+ G   SQ  +    Q    QR  + L   Q     +R  +E       
Sbjct: 2666 D--------PGMSGL--SQTELEKQRQR---QRLRELLIRQQIQRNTLRQEKETAAAA-- 2710

Query: 443  PSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKED-----ARPPSS 497
                        +   GPP      P   + PA    +R        +D       PPS 
Sbjct: 2711 ------------AGAVGPPGSWGAEP---SSPAFEQLSRGQTPFAGTQDKSSLVGLPPSK 2755

Query: 498  PPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEG 557
               P++       P  D L  P P                PAT    D   R  +   + 
Sbjct: 2756 LSGPILGP--GSFPSDDRLSRPPP----------------PATPSSMDVNSRQLVGGSQA 2797

Query: 558  PSGSKPLRGSLK-EEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLP 616
                 P  GSL  ++    L  ++    A+ ++ + S            P++G      P
Sbjct: 2798 FYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPG----PELGRQALGSP 2853

Query: 617  GLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRP--APLPAAVVPSTPTSA 674
             L  I T  PG PG PV   A P       +       K L P   P P    P  P   
Sbjct: 2854 -LAGISTRLPG-PGEPVPGPAGPA----QFIELRHNVQKGLGPGGTPFPGQGPPQRPRFY 2907

Query: 675  PAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQ- 733
            P    P      G  GL +    P   +    A P+P       P P       P   + 
Sbjct: 2908 PVSEDPHRLAPEGLRGLAVSGLPPQKPS----APPAPELNNSLHPTPHTKGPTLPTGLEL 2963

Query: 734  ---APASARDPAPAP-APVAGPAPASTSAPGDSLEQH 766
                P+S     P P A  AG  P       D  + H
Sbjct: 2964 VNRPPSSTELGRPNPLALEAGKLPCEDPELDDDFDAH 3000



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 41/140 (29%), Positives = 48/140 (34%), Gaps = 31/140 (22%)

Query: 657  LRPAPLPAAVVPSTPTSAP-----APTQPAPTPTS------------------GPIGLRI 693
            LR  P P A+    P +AP     +PT PA   TS                  G + L++
Sbjct: 2104 LRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKL 2163

Query: 694  LAQQPLSVTC---FSLA--LPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPV 748
              Q P  V     F LA   P  P    A P   P PSP  A AQ P       P     
Sbjct: 2164 PPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPG---A 2220

Query: 749  AGPAPASTSAPGDSLEQHFT 768
              P    T+ PG    Q  T
Sbjct: 2221 GQPGEFHTTPPGTPRHQPST 2240



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 33/126 (26%), Positives = 45/126 (35%), Gaps = 23/126 (18%)

Query: 660  APLPAAVVPSTPTS----APAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVA 715
            +P P +  PS P S    AP    P P P         LA   L    F  ALP+ PA  
Sbjct: 2446 SPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGE 2505

Query: 716  VASPAPAPAP--------------SPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGD 761
            + +  P+  P              +P+P R   P +  +P+  P     P P     P  
Sbjct: 2506 LHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKP-----PVPQPGLPPPH 2560

Query: 762  SLEQHF 767
             +  HF
Sbjct: 2561 GINSHF 2566



 Score = 33.9 bits (76), Expect = 0.82
 Identities = 94/402 (23%), Positives = 130/402 (32%), Gaps = 84/402 (20%)

Query: 403  NVRAVPQPGAFQRACQPLPASQPC---SEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSG 459
            ++R  PQPGA      P PA+ P      P  PA        L +     L+P      G
Sbjct: 2103 HLRIPPQPGALG---SPPPAAAPTIFIGSPTTPAG-------LSTSADGFLKPPAGSVPG 2152

Query: 460  PPIVIRDSP----------VPCTPPALPPCA-RECQSLPQKEDARPPSSPPMPVIDNVFS 508
            P     DSP          VP   P+  P        L  +    PP+ PP P      +
Sbjct: 2153 P-----DSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPA 2207

Query: 509  LAPY-----RDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRG-TLPAQEGPSGSK 562
              P      R     P    TT P +   +P +     + +        +P   G  G K
Sbjct: 2208 QPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGK 2267

Query: 563  PLRGSLKE----EVALDLSVRKPTAEASPVKASRSVEHAKPTAA-MDVPDVGNMVSDL-- 615
                 L      E    L V+K    AS      S  +  P    +D P  G  +  L  
Sbjct: 2268 ASEPLLSPPPFGESRKALEVKKEELGAS------SPSYGPPNLGFVDSPSSGTHLGGLEL 2321

Query: 616  -----------PGLKKIDTEAPGL---PGVPVTTDAM-PRTNFHSSVAFMFRKFKILRPA 660
                       P   +++ ++PGL   P  P    A+ P    H  +   FR      P 
Sbjct: 2322 KTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDI---FRPGSYTDPY 2378

Query: 661  PLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPA 720
              P    P TP       QP P  +   +  R L   P S       +P+ P    +S +
Sbjct: 2379 AQP----PLTPRP-----QPPPPESCCALPPRSLPSDPFS------RVPASPQSQSSSQS 2423

Query: 721  P-APAPSPAPARAQAPASARDPAPAP--APVAGPAPASTSAP 759
            P  P P  A A   +P + R  +P P   P + P      AP
Sbjct: 2424 PLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAP 2465



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 26/79 (32%), Positives = 34/79 (43%), Gaps = 15/79 (18%)

Query: 673  SAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAP-AR 731
            SAP P +P+P P+        LA  P S        P+ P V + +   A  P P+P   
Sbjct: 4907 SAPPPEEPSPPPSP-------LAPSPASP-------PTEPLVELPTEPLAEPPVPSPLPL 4952

Query: 732  AQAPASARDPAPAPAPVAG 750
            A +P SAR    A  P  G
Sbjct: 4953 ASSPESARPKPRARPPEEG 4971



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 30/114 (26%), Positives = 42/114 (36%), Gaps = 18/114 (15%)

Query: 937  SSEPTVARDEPESLALAQKSP---APKVRKPGRKPPTPGPEKAEAAAGEESCGASPTPAT 993
            S  P V+R  P  +      P   +P    P   P +P PE +  +   E    SP P  
Sbjct: 645  SPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPED 704

Query: 994  SASPPGPTLKARFRSLLETAWLNGLALPTWGHKSSRPDQPSPCPQLLDSQSHHL 1047
            S + P P       SL+         LP        P++P  CP+   S+  HL
Sbjct: 705  SPASPPPE-----DSLMSLPLEESPLLPL-------PEEPQLCPR---SEGPHL 743



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 30/119 (25%), Positives = 42/119 (35%), Gaps = 8/119 (6%)

Query: 682  PTPTSGPI---GLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASA 738
            P P +GP+   G     Q P  +     AL + P +    P P P+    P R     S 
Sbjct: 4267 PGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSP 4326

Query: 739  RDPAPAPAPVAGPAPASTSAPGDSLEQ---HFTGLHASLCDAI--SGSVAHSPPEKLRE 792
                P  A +    P +    G +LE      +   A L D +   G     PP+ L E
Sbjct: 4327 SSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAE 4385



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 13/92 (14%)

Query: 670  TPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAP 729
            +P   P PTQ + T     + +R L+  P          PSPP   +A   P+PA  P  
Sbjct: 4883 SPAPEP-PTQHSYTYNVSNLDVRQLSAPPPEE-------PSPPPSPLA---PSPASPPTE 4931

Query: 730  ARAQAPAS--ARDPAPAPAPVAGPAPASTSAP 759
               + P    A  P P+P P+A    ++   P
Sbjct: 4932 PLVELPTEPLAEPPVPSPLPLASSPESARPKP 4963


>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
          Length = 1711

 Score = 71.2 bits (173), Expect = 5e-12
 Identities = 85/295 (28%), Positives = 104/295 (35%), Gaps = 83/295 (28%)

Query: 468 PVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEP 527
           P P  PPA P  A    S+P  +  + P S P PV  +   L P +    VPAP     P
Sbjct: 200 PAPICPPA-PGSASVPHSVP--DAFQVPLSVPAPVPHS--GLVPVQVATSVPAPSPPLAP 254

Query: 528 DSATAE-PDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEAS 586
             A A  P S P      +       P     S   P+  S      + LS   P   + 
Sbjct: 255 VPALAPAPPSVPTLISDSN-------PLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSV 307

Query: 587 PVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSS 646
           PV A        P A +  P              +   AP L   PV T  +        
Sbjct: 308 PVSAP-------PLALIQAP--------------VPPSAPTLVLAPVPTPVL-------- 338

Query: 647 VAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQ---PAPTPTSGPIGLRILAQQPLSVTC 703
                        AP+PA    STP +APAP     P PTP+SGP               
Sbjct: 339 -------------APMPA----STPPAAPAPPSVPMPTPTPSSGP--------------- 366

Query: 704 FSLALPSPPAVAVA-SPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTS 757
                PS P +  A +P P PAP+PAP    AP       PA  P + P PAS S
Sbjct: 367 -----PSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFS 416



 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 63/203 (31%), Positives = 82/203 (40%), Gaps = 28/203 (13%)

Query: 581 PTAEASPVKASRSVEHAKPTAAM-------DVPDVG--------NMVSDLPGLKKIDTEA 625
           P     P   S SV H+ P A          VP  G        ++ +  P L  +   A
Sbjct: 200 PAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALA 259

Query: 626 PGLPGVP-VTTDAMPRTNFHSSVAFMFRKFKILRPAPL--PAAVVPSTPTSAP------A 676
           P  P VP + +D+ P +   S +  +        P PL  PA    S P SAP      A
Sbjct: 260 PAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQA 319

Query: 677 PTQP-APTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAP 735
           P  P APT    P+   +LA  P S      A P+PP+V + +P P+  P   P    A 
Sbjct: 320 PVPPSAPTLVLAPVPTPVLAPMPASTPP---AAPAPPSVPMPTPTPSSGPPSTPTLIPAF 376

Query: 736 ASARDPAPAPAPVAGPAPASTSA 758
           A    PAP PAP+  PAP    A
Sbjct: 377 APTPVPAPTPAPIFTPAPTPMPA 399



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 109/441 (24%), Positives = 157/441 (35%), Gaps = 68/441 (15%)

Query: 329 AAQAPYIPPLGLDAYPYP-SAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSL 387
           +A  P+  P   DA+  P S P P P  GL          P+  A    S P     L+ 
Sbjct: 210 SASVPHSVP---DAFQVPLSVPAPVPHSGL---------VPVQVAT---SVPAPSPPLA- 253

Query: 388 YGASPGLGGTPPSQNNVRAVPQPGAFQRACQ-PLPASQPCSEPVRPAQEAEEKTWLP-SC 445
               P L   PPS   + +   P +   +   P+PAS P S PV  +  A     +P S 
Sbjct: 254 --PVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSA 311

Query: 446 RKEKLQPRLSEHSGPPIVIRDSPVPCTPP---ALPPCARECQSLPQKEDARPPSSPPMPV 502
               L       S P +V+   P P   P   + PP A    S+P          P  P 
Sbjct: 312 PPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPT 371

Query: 503 IDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKG---CRGTLPAQEGPS 559
           +   F+  P       PAP  T  P    A   +A  TS          R   PA + P+
Sbjct: 372 LIPAFAPTPVP--APTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPA 429

Query: 560 GSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAK-PT-----AAMDVPDVGNMVS 613
             K     L  +    L+  +P     P    + +  A  PT     + + +P + + + 
Sbjct: 430 MQKV---PLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQ 486

Query: 614 D--LPGLKKIDTEAPGLPGVPVTTD-AMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPST 670
           D  LPG+      +P L   P     A P T+    V+    +             +P T
Sbjct: 487 DRCLPGV----LASPELRSYPYAFSVARPLTSDSKLVSLEVNR-------------LPCT 529

Query: 671 PTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSP----PAVAVASPAPAPAPS 726
             S    TQPAP    GP+    L      VT  +  LP+P    PA + +S  P PA  
Sbjct: 530 SPSGSTTTQPAPDGVPGPLADTSL------VTASAKVLPTPQPLLPAPSGSSAPPHPAKM 583

Query: 727 PAPARAQAPASARDPAPAPAP 747
           P+    Q   ++   +P  +P
Sbjct: 584 PSGTEQQTEGTSVTFSPLKSP 604



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 37/131 (28%), Positives = 46/131 (35%), Gaps = 30/131 (22%)

Query: 660 APLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASP 719
           +PLPA + P           PAP   S P  +    Q PLSV                  
Sbjct: 197 SPLPAPICP-----------PAPGSASVPHSVPDAFQVPLSV------------------ 227

Query: 720 APAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQHFTGLHASLCDAIS 779
            PAP P       Q   S   P+P  APV   APA  S P    + +   + AS+   + 
Sbjct: 228 -PAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVP 286

Query: 780 GSVAHSPPEKL 790
            S   S P  L
Sbjct: 287 ASAPPSGPVPL 297



 Score = 34.3 bits (77), Expect = 0.63
 Identities = 80/353 (22%), Positives = 108/353 (30%), Gaps = 71/353 (20%)

Query: 246 PSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQ 305
           PS+P   LA P+  P     P   PP    PP  P   P P                   
Sbjct: 323 PSAPTLVLA-PVPTPVLAPMPASTPPAAPAPPSVPMPTPTP------------------- 362

Query: 306 PLGGHKGTGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEPPLTP 365
                      +G   +P L    A  P   P     +     P+PA +P      P + 
Sbjct: 363 ----------SSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPA---AIPTSA 409

Query: 366 RCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPL----- 420
             P  F+   + FP A+                P+   V    QPG      QPL     
Sbjct: 410 PIPASFSLSRVCFPAAQ---------------APAMQKVPLSFQPGTVLTPSQPLVYIPP 454

Query: 421 -PASQPCSEPVRPAQEAEEKTW----LPSCRKEK------LQPRLSEHSGPPIVIRDSPV 469
               QP S    P       T     LPS  +++        P L  +     V R    
Sbjct: 455 PSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTS 514

Query: 470 PCTPPALPPCARECQSLPQKEDARP-PSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPD 528
                +L      C S       +P P   P P+ D     A  +  L  P P     P 
Sbjct: 515 DSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAK-VLPTPQP-LLPAPS 572

Query: 529 SATAEPDSA--PATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKE--EVALDLS 577
            ++A P  A  P+ +E Q +G   T    + P   +    S  E  E+ LDLS
Sbjct: 573 GSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLS 625


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 126/605 (20%), Positives = 182/605 (30%), Gaps = 82/605 (13%)

Query: 195 PAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYPRNSKQAMSEGPSSPWTQLA 254
           PA  + K+ + +     P   K     +T    +    P P  +K+     P  P     
Sbjct: 224 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 283

Query: 255 QPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTG 314
           +   P    + PT   P    P  P +  P  P    P      +P  P +P    K   
Sbjct: 284 KEPAPTTTKSAPT--TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 341

Query: 315 YQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEP-PLTPRCPLDF-- 371
                      ++ A  AP  P       P P+ P   P+P    EP P TP+ P     
Sbjct: 342 PTTP-------KEPAPTAPKKPAPTTPKEPAPTTP-KEPAPTTTKEPSPTTPKEPAPTTT 393

Query: 372 --APQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEP 429
             AP T   P                  P +  +    P+  +     +P P +     P
Sbjct: 394 KSAPTTTKEP-----------------APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 436

Query: 430 VRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQK 489
             P + A      P+    K +P  +    P       P P TP    P   + +  P  
Sbjct: 437 TTPKKPAPTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTT 494

Query: 490 EDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCR 549
            +   P++P  P       LAP     + P P    EP      P +  A +    K   
Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTP--EEPTPTTPEEP-----APTTPKAAAPNTPKEPA 547

Query: 550 GTLPAQEGPSGSK-PLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDV 608
            T P +  P+  K P   + KE          PT    P   +      K  A     + 
Sbjct: 548 PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 607

Query: 609 GNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVP 668
            +   D P        AP  P  P  T                           P    P
Sbjct: 608 TSTTCDKPAPTTPKGTAPTTPKEPAPTT--------------------------PKEPAP 641

Query: 669 STPTSAPAPT---QPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAP 725
           +TP    APT   +PAPT    P      A + L+ T        P +     PAP    
Sbjct: 642 TTPKGT-APTTLKEPAPTTPKKP------APKELAPT----TTKGPTSTTSDKPAPTTPK 690

Query: 726 SPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQHFTGLHASLCDAISGSVAHS 785
             AP   + PA      PAP     P P ++     +  +  T +H S  ++     A  
Sbjct: 691 ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP 750

Query: 786 PPEKL 790
            P+ L
Sbjct: 751 TPKAL 755



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 100/430 (23%), Positives = 138/430 (32%), Gaps = 50/430 (11%)

Query: 342 AYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQ 401
           A P P A      P L      TP  P + A  T   P      S    +      P + 
Sbjct: 195 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS--APTTPKEPAPTTT 252

Query: 402 NNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTW-LPSCRKEKL-----QPRLS 455
            +    P+  A     +P P +     P    + A   T   P+  KE       +P  +
Sbjct: 253 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 312

Query: 456 EHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDY 515
               P       P P TP    P  +E      KE A  P++P  P        AP    
Sbjct: 313 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA--PTAPKKPAPTTPKEPAPTTP- 369

Query: 516 LDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALD 575
              PAP  T EP S T   + AP T++        T   +  P+ +K    + KE     
Sbjct: 370 -KEPAPTTTKEP-SPTTPKEPAPTTTKSAP-----TTTKEPAPTTTKSAPTTPKEPSPTT 422

Query: 576 LSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTT 635
                PT    P  A  + +   PT   +              KK     P  P      
Sbjct: 423 TKEPAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 480

Query: 636 DAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILA 695
           +  P T             K L P   P  + P+TP   PAPT P     + P       
Sbjct: 481 ETAPTTP------------KKLTPTT-PEKLAPTTPEK-PAPTTPEELAPTTP------- 519

Query: 696 QQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAP------APAPVA 749
           ++P   T      P+P     A+P     P+P   +  AP + ++PAP      AP    
Sbjct: 520 EEPTPTTPEE---PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 576

Query: 750 GPAPASTSAP 759
           G AP +   P
Sbjct: 577 GTAPTTLKEP 586



 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 75/322 (23%), Positives = 109/322 (33%), Gaps = 25/322 (7%)

Query: 446 RKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARP----PSSPPMP 501
           +K   +P + + +G  +   D  V  TP        +  + P+   A+P    PS PP  
Sbjct: 76  KKPTPKPPVVDEAGSGLDNGDFKVT-TPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNS 134

Query: 502 VIDNVFSLAPYRDYLDVPAPEATTEPDSAT---AEPDSAPATSEGQDKGCRGTLPAQEGP 558
                 SL   ++         TT   ++T    +  SA  T   +    +   P  +  
Sbjct: 135 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 194

Query: 559 SGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGL 618
           +   P   +  +  AL  + ++PT       AS + +   PT     P         P  
Sbjct: 195 AKPTPKAETTTKGPALT-TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK--EPAPTT 251

Query: 619 KKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPT 678
            K     P  P    T +  P T    +            PAP      P+TP   PAPT
Sbjct: 252 TKSAPTTPKEPAPTTTKEPAPTTPKEPAPT------TTKEPAPTTTKSAPTTPKE-PAPT 304

Query: 679 QPA-PTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPAS 737
            P  P PT+         ++P   T      P  PA     PAP     PAP   + PA 
Sbjct: 305 TPKKPAPTTPKEPAPTTPKEPTPTT------PKEPAPTTKEPAPTTPKEPAPTAPKKPAP 358

Query: 738 ARDPAPAPAPVAGPAPASTSAP 759
                PAP     PAP +T  P
Sbjct: 359 TTPKEPAPTTPKEPAPTTTKEP 380



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 68/295 (23%), Positives = 96/295 (32%), Gaps = 35/295 (11%)

Query: 473 PPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATA 532
           P   PP   E  S     D +  +        N  S +P         P  +  P+S T+
Sbjct: 78  PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 137

Query: 533 EPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASR 592
           +  S     E   +    T   ++  +  K    S KE  +++ +  K  A  S V A  
Sbjct: 138 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-- 195

Query: 593 SVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFR 652
                KPT   +    G      P L       P  P  P +T     T           
Sbjct: 196 -----KPTPKAETTTKG------PALTTPKEPTPTTPKEPASTTPKEPTP---------- 234

Query: 653 KFKILRPAPL-PAAVVPSTPTSAPA-PTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPS 710
               ++ AP  P    P+T  SAP  P +PAPT T  P       ++P   T        
Sbjct: 235 --TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT--PKEPAPTTT------K 284

Query: 711 PPAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQ 765
            PA      AP     PAP   + PA      PAP     P P +   P  + ++
Sbjct: 285 EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE 339



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 109/492 (22%), Positives = 163/492 (33%), Gaps = 71/492 (14%)

Query: 233 PYPRNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHP 292
           P P  +K+     P  P      P  P  ++T PT   P    P  P +  P  P    P
Sbjct: 458 PAPTTTKKPAPTTPKEP-----APTTP--KETAPT--TPKKLTPTTPEKLAPTTPEKPAP 508

Query: 293 EKQGSYSPALPLQPLGGHKG----TGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSA 348
                 +P  P +P          T  +A    +P  ++ A   P  P       P P+ 
Sbjct: 509 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP--KEPAPTTPKEPAPTTPKEPAPTT 566

Query: 349 P---LPAPSPG-----LKLEPPLTPR--CPLDFAPQTLSFPYARDDLSLYGASPGLGGTP 398
           P    P    G     LK   P TP+   P + AP T   P +         +P   GT 
Sbjct: 567 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK--GTA 624

Query: 399 PSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHS 458
           P+       P+  A     +P P +   + P    + A      P+   ++L P  ++  
Sbjct: 625 PT------TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTK-- 674

Query: 459 GPPIVIRDSPVPCTPPALPPCARE--CQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYL 516
           GP     D P P TP    P   +    + P+K     P +PP P    V +        
Sbjct: 675 GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP-PTTSEVST-------- 725

Query: 517 DVPAPEATT---EPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKP-LRGSLKEEV 572
                E TT    PD +T E  + P     ++      +P  + P+ +KP +  + K++ 
Sbjct: 726 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 785

Query: 573 A-LDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVS-----DLPGLK----KID 622
              DL     T  A+P     +    + T    +      V+     D    K    K  
Sbjct: 786 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 845

Query: 623 TEAPGLPGVP---VTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAP-- 677
           T AP +        TT+ M +    +         K   P P      P  PTS   P  
Sbjct: 846 TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT 905

Query: 678 ----TQPAPTPT 685
                +P  TPT
Sbjct: 906 MPRVRKPKTTPT 917



 Score = 34.3 bits (77), Expect = 0.63
 Identities = 62/290 (21%), Positives = 96/290 (33%), Gaps = 31/290 (10%)

Query: 101 PEKMQDSSPVELLPFSPQAHSYPGPPLAAP----KPVYRNPLCYGLSTCLGEGAVKRPLD 156
           PE++  ++P E  P +P+  +   P  AAP    +P    P      T   E A   P +
Sbjct: 511 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK-EPAPTTPKEPAPTTPKE 569

Query: 157 VDWTLATG----------PLLPSADPPCSLAPAPSKGQTLDGTFLRGVPA--EGSSKDSS 204
              T   G          P  P    P  LAP  +K  T   T  +  P   +G++  + 
Sbjct: 570 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT-STTCDKPAPTTPKGTAPTTP 628

Query: 205 GSFSPCQPFLEKYQTIHSTGFLASRYTG------PYPRNSKQAMSEGPSSPWTQLAQPLG 258
              +P  P      T   T     +         P P+      ++GP+S  +    P  
Sbjct: 629 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 688

Query: 259 PPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAG 318
           P  ++T PT   P    P  P +  P  P    P      +P    +P   HK       
Sbjct: 689 P--KETAPT--TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 744

Query: 319 GLG---SPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEPPLTP 365
            L    +P   + + + P +P     A   P     A     + +   TP
Sbjct: 745 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP 794


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 126/605 (20%), Positives = 182/605 (30%), Gaps = 82/605 (13%)

Query: 195 PAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYPRNSKQAMSEGPSSPWTQLA 254
           PA  + K+ + +     P   K     +T    +    P P  +K+     P  P     
Sbjct: 265 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 324

Query: 255 QPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTG 314
           +   P    + PT   P    P  P +  P  P    P      +P  P +P    K   
Sbjct: 325 KEPAPTTTKSAPT--TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 382

Query: 315 YQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEP-PLTPRCPLDF-- 371
                      ++ A  AP  P       P P+ P   P+P    EP P TP+ P     
Sbjct: 383 PTTP-------KEPAPTAPKKPAPTTPKEPAPTTP-KEPAPTTTKEPSPTTPKEPAPTTT 434

Query: 372 --APQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEP 429
             AP T   P                  P +  +    P+  +     +P P +     P
Sbjct: 435 KSAPTTTKEP-----------------APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 477

Query: 430 VRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQK 489
             P + A      P+    K +P  +    P       P P TP    P   + +  P  
Sbjct: 478 TTPKKPAPTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTT 535

Query: 490 EDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCR 549
            +   P++P  P       LAP     + P P    EP      P +  A +    K   
Sbjct: 536 PEKLAPTTPEKPAPTTPEELAPTTP--EEPTPTTPEEP-----APTTPKAAAPNTPKEPA 588

Query: 550 GTLPAQEGPSGSK-PLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDV 608
            T P +  P+  K P   + KE          PT    P   +      K  A     + 
Sbjct: 589 PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 648

Query: 609 GNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVP 668
            +   D P        AP  P  P  T                           P    P
Sbjct: 649 TSTTCDKPAPTTPKGTAPTTPKEPAPTT--------------------------PKEPAP 682

Query: 669 STPTSAPAPT---QPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAP 725
           +TP    APT   +PAPT    P      A + L+ T        P +     PAP    
Sbjct: 683 TTPKGT-APTTLKEPAPTTPKKP------APKELAPT----TTKGPTSTTSDKPAPTTPK 731

Query: 726 SPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQHFTGLHASLCDAISGSVAHS 785
             AP   + PA      PAP     P P ++     +  +  T +H S  ++     A  
Sbjct: 732 ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP 791

Query: 786 PPEKL 790
            P+ L
Sbjct: 792 TPKAL 796



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 100/430 (23%), Positives = 138/430 (32%), Gaps = 50/430 (11%)

Query: 342 AYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQ 401
           A P P A      P L      TP  P + A  T   P      S    +      P + 
Sbjct: 236 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS--APTTPKEPAPTTT 293

Query: 402 NNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTW-LPSCRKEKL-----QPRLS 455
            +    P+  A     +P P +     P    + A   T   P+  KE       +P  +
Sbjct: 294 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 353

Query: 456 EHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDY 515
               P       P P TP    P  +E      KE A  P++P  P        AP    
Sbjct: 354 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA--PTAPKKPAPTTPKEPAPTTP- 410

Query: 516 LDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALD 575
              PAP  T EP S T   + AP T++        T   +  P+ +K    + KE     
Sbjct: 411 -KEPAPTTTKEP-SPTTPKEPAPTTTKSAP-----TTTKEPAPTTTKSAPTTPKEPSPTT 463

Query: 576 LSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTT 635
                PT    P  A  + +   PT   +              KK     P  P      
Sbjct: 464 TKEPAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 521

Query: 636 DAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILA 695
           +  P T             K L P   P  + P+TP   PAPT P     + P       
Sbjct: 522 ETAPTTP------------KKLTPTT-PEKLAPTTPEK-PAPTTPEELAPTTP------- 560

Query: 696 QQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAP------APAPVA 749
           ++P   T      P+P     A+P     P+P   +  AP + ++PAP      AP    
Sbjct: 561 EEPTPTTPEE---PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 617

Query: 750 GPAPASTSAP 759
           G AP +   P
Sbjct: 618 GTAPTTLKEP 627



 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 75/322 (23%), Positives = 109/322 (33%), Gaps = 25/322 (7%)

Query: 446 RKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARP----PSSPPMP 501
           +K   +P + + +G  +   D  V  TP        +  + P+   A+P    PS PP  
Sbjct: 117 KKPTPKPPVVDEAGSGLDNGDFKVT-TPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNS 175

Query: 502 VIDNVFSLAPYRDYLDVPAPEATTEPDSAT---AEPDSAPATSEGQDKGCRGTLPAQEGP 558
                 SL   ++         TT   ++T    +  SA  T   +    +   P  +  
Sbjct: 176 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 235

Query: 559 SGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGL 618
           +   P   +  +  AL  + ++PT       AS + +   PT     P         P  
Sbjct: 236 AKPTPKAETTTKGPALT-TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK--EPAPTT 292

Query: 619 KKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPT 678
            K     P  P    T +  P T    +            PAP      P+TP   PAPT
Sbjct: 293 TKSAPTTPKEPAPTTTKEPAPTTPKEPAPT------TTKEPAPTTTKSAPTTPKE-PAPT 345

Query: 679 QPA-PTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPAS 737
            P  P PT+         ++P   T      P  PA     PAP     PAP   + PA 
Sbjct: 346 TPKKPAPTTPKEPAPTTPKEPTPTT------PKEPAPTTKEPAPTTPKEPAPTAPKKPAP 399

Query: 738 ARDPAPAPAPVAGPAPASTSAP 759
                PAP     PAP +T  P
Sbjct: 400 TTPKEPAPTTPKEPAPTTTKEP 421



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 68/295 (23%), Positives = 96/295 (32%), Gaps = 35/295 (11%)

Query: 473 PPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATA 532
           P   PP   E  S     D +  +        N  S +P         P  +  P+S T+
Sbjct: 119 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 178

Query: 533 EPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASR 592
           +  S     E   +    T   ++  +  K    S KE  +++ +  K  A  S V A  
Sbjct: 179 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-- 236

Query: 593 SVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFR 652
                KPT   +    G      P L       P  P  P +T     T           
Sbjct: 237 -----KPTPKAETTTKG------PALTTPKEPTPTTPKEPASTTPKEPTP---------- 275

Query: 653 KFKILRPAPL-PAAVVPSTPTSAPA-PTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPS 710
               ++ AP  P    P+T  SAP  P +PAPT T  P       ++P   T        
Sbjct: 276 --TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT--PKEPAPTTT------K 325

Query: 711 PPAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQ 765
            PA      AP     PAP   + PA      PAP     P P +   P  + ++
Sbjct: 326 EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE 380



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 109/492 (22%), Positives = 163/492 (33%), Gaps = 71/492 (14%)

Query: 233 PYPRNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHP 292
           P P  +K+     P  P      P  P  ++T PT   P    P  P +  P  P    P
Sbjct: 499 PAPTTTKKPAPTTPKEP-----APTTP--KETAPT--TPKKLTPTTPEKLAPTTPEKPAP 549

Query: 293 EKQGSYSPALPLQPLGGHKG----TGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSA 348
                 +P  P +P          T  +A    +P  ++ A   P  P       P P+ 
Sbjct: 550 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP--KEPAPTTPKEPAPTTPKEPAPTT 607

Query: 349 P---LPAPSPG-----LKLEPPLTPR--CPLDFAPQTLSFPYARDDLSLYGASPGLGGTP 398
           P    P    G     LK   P TP+   P + AP T   P +         +P   GT 
Sbjct: 608 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK--GTA 665

Query: 399 PSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHS 458
           P+       P+  A     +P P +   + P    + A      P+   ++L P  ++  
Sbjct: 666 PT------TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTK-- 715

Query: 459 GPPIVIRDSPVPCTPPALPPCARE--CQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYL 516
           GP     D P P TP    P   +    + P+K     P +PP P    V +        
Sbjct: 716 GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP-PTTSEVST-------- 766

Query: 517 DVPAPEATT---EPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKP-LRGSLKEEV 572
                E TT    PD +T E  + P     ++      +P  + P+ +KP +  + K++ 
Sbjct: 767 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 826

Query: 573 A-LDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVS-----DLPGLK----KID 622
              DL     T  A+P     +    + T    +      V+     D    K    K  
Sbjct: 827 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 886

Query: 623 TEAPGLPGVP---VTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAP-- 677
           T AP +        TT+ M +    +         K   P P      P  PTS   P  
Sbjct: 887 TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT 946

Query: 678 ----TQPAPTPT 685
                +P  TPT
Sbjct: 947 MPRVRKPKTTPT 958



 Score = 34.3 bits (77), Expect = 0.63
 Identities = 62/290 (21%), Positives = 96/290 (33%), Gaps = 31/290 (10%)

Query: 101 PEKMQDSSPVELLPFSPQAHSYPGPPLAAP----KPVYRNPLCYGLSTCLGEGAVKRPLD 156
           PE++  ++P E  P +P+  +   P  AAP    +P    P      T   E A   P +
Sbjct: 552 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK-EPAPTTPKEPAPTTPKE 610

Query: 157 VDWTLATG----------PLLPSADPPCSLAPAPSKGQTLDGTFLRGVPA--EGSSKDSS 204
              T   G          P  P    P  LAP  +K  T   T  +  P   +G++  + 
Sbjct: 611 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT-STTCDKPAPTTPKGTAPTTP 669

Query: 205 GSFSPCQPFLEKYQTIHSTGFLASRYTG------PYPRNSKQAMSEGPSSPWTQLAQPLG 258
              +P  P      T   T     +         P P+      ++GP+S  +    P  
Sbjct: 670 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 729

Query: 259 PPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAG 318
           P  ++T PT   P    P  P +  P  P    P      +P    +P   HK       
Sbjct: 730 P--KETAPT--TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 785

Query: 319 GLG---SPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEPPLTP 365
            L    +P   + + + P +P     A   P     A     + +   TP
Sbjct: 786 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP 835


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 126/605 (20%), Positives = 182/605 (30%), Gaps = 82/605 (13%)

Query: 195 PAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYPRNSKQAMSEGPSSPWTQLA 254
           PA  + K+ + +     P   K     +T    +    P P  +K+     P  P     
Sbjct: 317 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 376

Query: 255 QPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTG 314
           +   P    + PT   P    P  P +  P  P    P      +P  P +P    K   
Sbjct: 377 KEPAPTTTKSAPT--TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 434

Query: 315 YQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEP-PLTPRCPLDF-- 371
                      ++ A  AP  P       P P+ P   P+P    EP P TP+ P     
Sbjct: 435 PTTP-------KEPAPTAPKKPAPTTPKEPAPTTP-KEPAPTTTKEPSPTTPKEPAPTTT 486

Query: 372 --APQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEP 429
             AP T   P                  P +  +    P+  +     +P P +     P
Sbjct: 487 KSAPTTTKEP-----------------APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 529

Query: 430 VRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQK 489
             P + A      P+    K +P  +    P       P P TP    P   + +  P  
Sbjct: 530 TTPKKPAPTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTT 587

Query: 490 EDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCR 549
            +   P++P  P       LAP     + P P    EP      P +  A +    K   
Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTP--EEPTPTTPEEP-----APTTPKAAAPNTPKEPA 640

Query: 550 GTLPAQEGPSGSK-PLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDV 608
            T P +  P+  K P   + KE          PT    P   +      K  A     + 
Sbjct: 641 PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 700

Query: 609 GNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVP 668
            +   D P        AP  P  P  T                           P    P
Sbjct: 701 TSTTCDKPAPTTPKGTAPTTPKEPAPTT--------------------------PKEPAP 734

Query: 669 STPTSAPAPT---QPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAP 725
           +TP    APT   +PAPT    P      A + L+ T        P +     PAP    
Sbjct: 735 TTPKGT-APTTLKEPAPTTPKKP------APKELAPT----TTKGPTSTTSDKPAPTTPK 783

Query: 726 SPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQHFTGLHASLCDAISGSVAHS 785
             AP   + PA      PAP     P P ++     +  +  T +H S  ++     A  
Sbjct: 784 ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP 843

Query: 786 PPEKL 790
            P+ L
Sbjct: 844 TPKAL 848



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 100/430 (23%), Positives = 138/430 (32%), Gaps = 50/430 (11%)

Query: 342 AYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQ 401
           A P P A      P L      TP  P + A  T   P      S    +      P + 
Sbjct: 288 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS--APTTPKEPAPTTT 345

Query: 402 NNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTW-LPSCRKEKL-----QPRLS 455
            +    P+  A     +P P +     P    + A   T   P+  KE       +P  +
Sbjct: 346 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 405

Query: 456 EHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDY 515
               P       P P TP    P  +E      KE A  P++P  P        AP    
Sbjct: 406 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA--PTAPKKPAPTTPKEPAPTTP- 462

Query: 516 LDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALD 575
              PAP  T EP S T   + AP T++        T   +  P+ +K    + KE     
Sbjct: 463 -KEPAPTTTKEP-SPTTPKEPAPTTTKSAP-----TTTKEPAPTTTKSAPTTPKEPSPTT 515

Query: 576 LSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTT 635
                PT    P  A  + +   PT   +              KK     P  P      
Sbjct: 516 TKEPAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 573

Query: 636 DAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILA 695
           +  P T             K L P   P  + P+TP   PAPT P     + P       
Sbjct: 574 ETAPTTP------------KKLTPTT-PEKLAPTTPEK-PAPTTPEELAPTTP------- 612

Query: 696 QQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAP------APAPVA 749
           ++P   T      P+P     A+P     P+P   +  AP + ++PAP      AP    
Sbjct: 613 EEPTPTTPEE---PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 669

Query: 750 GPAPASTSAP 759
           G AP +   P
Sbjct: 670 GTAPTTLKEP 679



 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 75/322 (23%), Positives = 109/322 (33%), Gaps = 25/322 (7%)

Query: 446 RKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARP----PSSPPMP 501
           +K   +P + + +G  +   D  V  TP        +  + P+   A+P    PS PP  
Sbjct: 169 KKPTPKPPVVDEAGSGLDNGDFKVT-TPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNS 227

Query: 502 VIDNVFSLAPYRDYLDVPAPEATTEPDSAT---AEPDSAPATSEGQDKGCRGTLPAQEGP 558
                 SL   ++         TT   ++T    +  SA  T   +    +   P  +  
Sbjct: 228 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 287

Query: 559 SGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGL 618
           +   P   +  +  AL  + ++PT       AS + +   PT     P         P  
Sbjct: 288 AKPTPKAETTTKGPALT-TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK--EPAPTT 344

Query: 619 KKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPT 678
            K     P  P    T +  P T    +            PAP      P+TP   PAPT
Sbjct: 345 TKSAPTTPKEPAPTTTKEPAPTTPKEPAPT------TTKEPAPTTTKSAPTTPKE-PAPT 397

Query: 679 QPA-PTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPAS 737
            P  P PT+         ++P   T      P  PA     PAP     PAP   + PA 
Sbjct: 398 TPKKPAPTTPKEPAPTTPKEPTPTT------PKEPAPTTKEPAPTTPKEPAPTAPKKPAP 451

Query: 738 ARDPAPAPAPVAGPAPASTSAP 759
                PAP     PAP +T  P
Sbjct: 452 TTPKEPAPTTPKEPAPTTTKEP 473



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 68/295 (23%), Positives = 96/295 (32%), Gaps = 35/295 (11%)

Query: 473 PPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATA 532
           P   PP   E  S     D +  +        N  S +P         P  +  P+S T+
Sbjct: 171 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 230

Query: 533 EPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASR 592
           +  S     E   +    T   ++  +  K    S KE  +++ +  K  A  S V A  
Sbjct: 231 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-- 288

Query: 593 SVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFR 652
                KPT   +    G      P L       P  P  P +T     T           
Sbjct: 289 -----KPTPKAETTTKG------PALTTPKEPTPTTPKEPASTTPKEPTP---------- 327

Query: 653 KFKILRPAPL-PAAVVPSTPTSAPA-PTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPS 710
               ++ AP  P    P+T  SAP  P +PAPT T  P       ++P   T        
Sbjct: 328 --TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT--PKEPAPTTT------K 377

Query: 711 PPAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQ 765
            PA      AP     PAP   + PA      PAP     P P +   P  + ++
Sbjct: 378 EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE 432



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 109/492 (22%), Positives = 163/492 (33%), Gaps = 71/492 (14%)

Query: 233  PYPRNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHP 292
            P P  +K+     P  P      P  P  ++T PT   P    P  P +  P  P    P
Sbjct: 551  PAPTTTKKPAPTTPKEP-----APTTP--KETAPT--TPKKLTPTTPEKLAPTTPEKPAP 601

Query: 293  EKQGSYSPALPLQPLGGHKG----TGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSA 348
                  +P  P +P          T  +A    +P  ++ A   P  P       P P+ 
Sbjct: 602  TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP--KEPAPTTPKEPAPTTPKEPAPTT 659

Query: 349  P---LPAPSPG-----LKLEPPLTPR--CPLDFAPQTLSFPYARDDLSLYGASPGLGGTP 398
            P    P    G     LK   P TP+   P + AP T   P +         +P   GT 
Sbjct: 660  PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK--GTA 717

Query: 399  PSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHS 458
            P+       P+  A     +P P +   + P    + A      P+   ++L P  ++  
Sbjct: 718  PT------TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTK-- 767

Query: 459  GPPIVIRDSPVPCTPPALPPCARE--CQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYL 516
            GP     D P P TP    P   +    + P+K     P +PP P    V +        
Sbjct: 768  GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP-PTTSEVST-------- 818

Query: 517  DVPAPEATT---EPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKP-LRGSLKEEV 572
                 E TT    PD +T E  + P     ++      +P  + P+ +KP +  + K++ 
Sbjct: 819  PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 878

Query: 573  A-LDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVS-----DLPGLK----KID 622
               DL     T  A+P     +    + T    +      V+     D    K    K  
Sbjct: 879  TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 938

Query: 623  TEAPGLPGVP---VTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAP-- 677
            T AP +        TT+ M +    +         K   P P      P  PTS   P  
Sbjct: 939  TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT 998

Query: 678  ----TQPAPTPT 685
                 +P  TPT
Sbjct: 999  MPRVRKPKTTPT 1010



 Score = 34.3 bits (77), Expect = 0.63
 Identities = 62/290 (21%), Positives = 96/290 (33%), Gaps = 31/290 (10%)

Query: 101 PEKMQDSSPVELLPFSPQAHSYPGPPLAAP----KPVYRNPLCYGLSTCLGEGAVKRPLD 156
           PE++  ++P E  P +P+  +   P  AAP    +P    P      T   E A   P +
Sbjct: 604 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK-EPAPTTPKEPAPTTPKE 662

Query: 157 VDWTLATG----------PLLPSADPPCSLAPAPSKGQTLDGTFLRGVPA--EGSSKDSS 204
              T   G          P  P    P  LAP  +K  T   T  +  P   +G++  + 
Sbjct: 663 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT-STTCDKPAPTTPKGTAPTTP 721

Query: 205 GSFSPCQPFLEKYQTIHSTGFLASRYTG------PYPRNSKQAMSEGPSSPWTQLAQPLG 258
              +P  P      T   T     +         P P+      ++GP+S  +    P  
Sbjct: 722 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 781

Query: 259 PPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAG 318
           P  ++T PT   P    P  P +  P  P    P      +P    +P   HK       
Sbjct: 782 P--KETAPT--TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 837

Query: 319 GLG---SPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEPPLTP 365
            L    +P   + + + P +P     A   P     A     + +   TP
Sbjct: 838 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP 887


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 126/605 (20%), Positives = 182/605 (30%), Gaps = 82/605 (13%)

Query: 195 PAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYPRNSKQAMSEGPSSPWTQLA 254
           PA  + K+ + +     P   K     +T    +    P P  +K+     P  P     
Sbjct: 358 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 417

Query: 255 QPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTG 314
           +   P    + PT   P    P  P +  P  P    P      +P  P +P    K   
Sbjct: 418 KEPAPTTTKSAPT--TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 475

Query: 315 YQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEP-PLTPRCPLDF-- 371
                      ++ A  AP  P       P P+ P   P+P    EP P TP+ P     
Sbjct: 476 PTTP-------KEPAPTAPKKPAPTTPKEPAPTTP-KEPAPTTTKEPSPTTPKEPAPTTT 527

Query: 372 --APQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEP 429
             AP T   P                  P +  +    P+  +     +P P +     P
Sbjct: 528 KSAPTTTKEP-----------------APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 570

Query: 430 VRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQK 489
             P + A      P+    K +P  +    P       P P TP    P   + +  P  
Sbjct: 571 TTPKKPAPTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTT 628

Query: 490 EDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCR 549
            +   P++P  P       LAP     + P P    EP      P +  A +    K   
Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTP--EEPTPTTPEEP-----APTTPKAAAPNTPKEPA 681

Query: 550 GTLPAQEGPSGSK-PLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDV 608
            T P +  P+  K P   + KE          PT    P   +      K  A     + 
Sbjct: 682 PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 741

Query: 609 GNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVP 668
            +   D P        AP  P  P  T                           P    P
Sbjct: 742 TSTTCDKPAPTTPKGTAPTTPKEPAPTT--------------------------PKEPAP 775

Query: 669 STPTSAPAPT---QPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAP 725
           +TP    APT   +PAPT    P      A + L+ T        P +     PAP    
Sbjct: 776 TTPKGT-APTTLKEPAPTTPKKP------APKELAPT----TTKGPTSTTSDKPAPTTPK 824

Query: 726 SPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQHFTGLHASLCDAISGSVAHS 785
             AP   + PA      PAP     P P ++     +  +  T +H S  ++     A  
Sbjct: 825 ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP 884

Query: 786 PPEKL 790
            P+ L
Sbjct: 885 TPKAL 889



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 100/430 (23%), Positives = 138/430 (32%), Gaps = 50/430 (11%)

Query: 342 AYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQ 401
           A P P A      P L      TP  P + A  T   P      S    +      P + 
Sbjct: 329 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS--APTTPKEPAPTTT 386

Query: 402 NNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTW-LPSCRKEKL-----QPRLS 455
            +    P+  A     +P P +     P    + A   T   P+  KE       +P  +
Sbjct: 387 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 446

Query: 456 EHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDY 515
               P       P P TP    P  +E      KE A  P++P  P        AP    
Sbjct: 447 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA--PTAPKKPAPTTPKEPAPTTP- 503

Query: 516 LDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALD 575
              PAP  T EP S T   + AP T++        T   +  P+ +K    + KE     
Sbjct: 504 -KEPAPTTTKEP-SPTTPKEPAPTTTKSAP-----TTTKEPAPTTTKSAPTTPKEPSPTT 556

Query: 576 LSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTT 635
                PT    P  A  + +   PT   +              KK     P  P      
Sbjct: 557 TKEPAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 614

Query: 636 DAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILA 695
           +  P T             K L P   P  + P+TP   PAPT P     + P       
Sbjct: 615 ETAPTTP------------KKLTPTT-PEKLAPTTPEK-PAPTTPEELAPTTP------- 653

Query: 696 QQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAP------APAPVA 749
           ++P   T      P+P     A+P     P+P   +  AP + ++PAP      AP    
Sbjct: 654 EEPTPTTPEE---PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 710

Query: 750 GPAPASTSAP 759
           G AP +   P
Sbjct: 711 GTAPTTLKEP 720



 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 75/322 (23%), Positives = 109/322 (33%), Gaps = 25/322 (7%)

Query: 446 RKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARP----PSSPPMP 501
           +K   +P + + +G  +   D  V  TP        +  + P+   A+P    PS PP  
Sbjct: 210 KKPTPKPPVVDEAGSGLDNGDFKVT-TPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNS 268

Query: 502 VIDNVFSLAPYRDYLDVPAPEATTEPDSAT---AEPDSAPATSEGQDKGCRGTLPAQEGP 558
                 SL   ++         TT   ++T    +  SA  T   +    +   P  +  
Sbjct: 269 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 328

Query: 559 SGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGL 618
           +   P   +  +  AL  + ++PT       AS + +   PT     P         P  
Sbjct: 329 AKPTPKAETTTKGPALT-TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK--EPAPTT 385

Query: 619 KKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPT 678
            K     P  P    T +  P T    +            PAP      P+TP   PAPT
Sbjct: 386 TKSAPTTPKEPAPTTTKEPAPTTPKEPAPT------TTKEPAPTTTKSAPTTPKE-PAPT 438

Query: 679 QPA-PTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPAS 737
            P  P PT+         ++P   T      P  PA     PAP     PAP   + PA 
Sbjct: 439 TPKKPAPTTPKEPAPTTPKEPTPTT------PKEPAPTTKEPAPTTPKEPAPTAPKKPAP 492

Query: 738 ARDPAPAPAPVAGPAPASTSAP 759
                PAP     PAP +T  P
Sbjct: 493 TTPKEPAPTTPKEPAPTTTKEP 514



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 68/295 (23%), Positives = 96/295 (32%), Gaps = 35/295 (11%)

Query: 473 PPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATA 532
           P   PP   E  S     D +  +        N  S +P         P  +  P+S T+
Sbjct: 212 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 271

Query: 533 EPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASR 592
           +  S     E   +    T   ++  +  K    S KE  +++ +  K  A  S V A  
Sbjct: 272 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-- 329

Query: 593 SVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFR 652
                KPT   +    G      P L       P  P  P +T     T           
Sbjct: 330 -----KPTPKAETTTKG------PALTTPKEPTPTTPKEPASTTPKEPTP---------- 368

Query: 653 KFKILRPAPL-PAAVVPSTPTSAPA-PTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPS 710
               ++ AP  P    P+T  SAP  P +PAPT T  P       ++P   T        
Sbjct: 369 --TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT--PKEPAPTTT------K 418

Query: 711 PPAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQ 765
            PA      AP     PAP   + PA      PAP     P P +   P  + ++
Sbjct: 419 EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE 473



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 109/492 (22%), Positives = 163/492 (33%), Gaps = 71/492 (14%)

Query: 233  PYPRNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHP 292
            P P  +K+     P  P      P  P  ++T PT   P    P  P +  P  P    P
Sbjct: 592  PAPTTTKKPAPTTPKEP-----APTTP--KETAPT--TPKKLTPTTPEKLAPTTPEKPAP 642

Query: 293  EKQGSYSPALPLQPLGGHKG----TGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSA 348
                  +P  P +P          T  +A    +P  ++ A   P  P       P P+ 
Sbjct: 643  TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP--KEPAPTTPKEPAPTTPKEPAPTT 700

Query: 349  P---LPAPSPG-----LKLEPPLTPR--CPLDFAPQTLSFPYARDDLSLYGASPGLGGTP 398
            P    P    G     LK   P TP+   P + AP T   P +         +P   GT 
Sbjct: 701  PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK--GTA 758

Query: 399  PSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHS 458
            P+       P+  A     +P P +   + P    + A      P+   ++L P  ++  
Sbjct: 759  PT------TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTK-- 808

Query: 459  GPPIVIRDSPVPCTPPALPPCARE--CQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYL 516
            GP     D P P TP    P   +    + P+K     P +PP P    V +        
Sbjct: 809  GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP-PTTSEVST-------- 859

Query: 517  DVPAPEATT---EPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKP-LRGSLKEEV 572
                 E TT    PD +T E  + P     ++      +P  + P+ +KP +  + K++ 
Sbjct: 860  PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 919

Query: 573  A-LDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVS-----DLPGLK----KID 622
               DL     T  A+P     +    + T    +      V+     D    K    K  
Sbjct: 920  TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 979

Query: 623  TEAPGLPGVP---VTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAP-- 677
            T AP +        TT+ M +    +         K   P P      P  PTS   P  
Sbjct: 980  TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT 1039

Query: 678  ----TQPAPTPT 685
                 +P  TPT
Sbjct: 1040 MPRVRKPKTTPT 1051



 Score = 34.3 bits (77), Expect = 0.63
 Identities = 62/290 (21%), Positives = 96/290 (33%), Gaps = 31/290 (10%)

Query: 101 PEKMQDSSPVELLPFSPQAHSYPGPPLAAP----KPVYRNPLCYGLSTCLGEGAVKRPLD 156
           PE++  ++P E  P +P+  +   P  AAP    +P    P      T   E A   P +
Sbjct: 645 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK-EPAPTTPKEPAPTTPKE 703

Query: 157 VDWTLATG----------PLLPSADPPCSLAPAPSKGQTLDGTFLRGVPA--EGSSKDSS 204
              T   G          P  P    P  LAP  +K  T   T  +  P   +G++  + 
Sbjct: 704 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT-STTCDKPAPTTPKGTAPTTP 762

Query: 205 GSFSPCQPFLEKYQTIHSTGFLASRYTG------PYPRNSKQAMSEGPSSPWTQLAQPLG 258
              +P  P      T   T     +         P P+      ++GP+S  +    P  
Sbjct: 763 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 822

Query: 259 PPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAG 318
           P  ++T PT   P    P  P +  P  P    P      +P    +P   HK       
Sbjct: 823 P--KETAPT--TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 878

Query: 319 GLG---SPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEPPLTP 365
            L    +P   + + + P +P     A   P     A     + +   TP
Sbjct: 879 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP 928


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 130/524 (24%), Positives = 180/524 (34%), Gaps = 98/524 (18%)

Query: 277 PHP-PQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQAPYI 335
           P P P A P PP     +   S S     +P    +      GGL  P  R  ++ A   
Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT-- 238

Query: 336 PPLGLDAYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLG 395
            PL   A   PSA     +P    +P   P+      P  ++ P  R D     A+P LG
Sbjct: 239 -PLSSPARSGPSARGTPRAPAHPSQPK--PKGLQALRPPQVTPP--RKD-----AAPALG 288

Query: 396 GTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLS 455
              P  ++  A P P A      P       S P  P  +A      P+     LQ   S
Sbjct: 289 ---PLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT-----LQATHS 340

Query: 456 EHSGPPIVIRDSPVPCTPPAL--PPCARECQSLPQKEDARPPSSP---PMPVIDNVFSLA 510
               PP+    +P P  PPAL  PP        P    A PP SP   P P   N  ++ 
Sbjct: 341 FLPSPPLSPLATPPPQAPPALALPPL-----QAPPSPPASPPLSPLATPSPQAPNALAVH 395

Query: 511 PYRDYLDVPAPEATTEPDSATAEPDSAP-ATSEGQDKGCRGTLPAQEGPS--GSKPLRGS 567
             +     P       P S  A P  +P AT   Q        P Q  PS   S P+  S
Sbjct: 396 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 455

Query: 568 LKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPG 627
                        P  +A P  A+  ++ AKP                          P 
Sbjct: 456 AT-----------PPPQAPPPLAAPPLQLAKPPPQAP---------------------PA 483

Query: 628 LPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSG 687
           L   P+     P  +F     F             P+A +P +P + P P   AP   + 
Sbjct: 484 LATPPLQALPSPPASFPGQAPFS------------PSASLPMSPLATPPPQ--APPVLAA 529

Query: 688 PIGLRILAQQPLSVTCFSLALPSPPAVAVASPAP----APAPSPAPARAQAPASARDPAP 743
           P+ L++    P S T  +   P  P    +   P    A AP P P  +++P+S      
Sbjct: 530 PL-LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL---- 584

Query: 744 APAPVAGPAPASTSAPGDSLEQHFTGLHASLCDAISGSVAHSPP 787
           +   +AG + ++TS P + L  + +G          G  A SPP
Sbjct: 585 SGPDLAGHSSSATSTP-EELRGYDSG--------PEGGAAASPP 619



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 154/626 (24%), Positives = 204/626 (32%), Gaps = 136/626 (21%)

Query: 165 PLLPSADPPCSLAPAPSKGQTLDGTFLRGVPAEG------SSKDSSGSFSPCQPFLEKYQ 218
           P  P+  P  S++ A     T      R  P+ G      +S+  S S +P         
Sbjct: 189 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 248

Query: 219 TIHSTGFLASRYTGPYPRNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPP-- 276
           +   T    +  + P P+  +       + P    A  LGP    + P   P P  PP  
Sbjct: 249 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP--LSSSPLATPSPSAPPSP 306

Query: 277 --PHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQAPY 334
             P   Q LP PPA   P  Q + S                    LGSP L+   +  P 
Sbjct: 307 SAPPSLQTLPSPPAT--PPSQATTS--------------------LGSPTLQATHSFLPS 344

Query: 335 IPPLGLDAYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGL 394
            PPL   A P P AP     P L+  PP  P  P   +P     P A + L+++      
Sbjct: 345 -PPLSPLATPPPQAPPALALPPLQA-PPSPPASP-PLSPLATPSPQAPNALAVHLLQAPF 401

Query: 395 GGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRL 454
             +PP    V+A   P          PAS P S    P  +A      PS     LQ   
Sbjct: 402 --SPPPSPPVQAPFSP----------PASPPVSPSATPPSQAP-----PSLAAPPLQVPP 444

Query: 455 SEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRD 514
           S  + PP+    +P P  PP L        + P  + A+PP   P               
Sbjct: 445 SPPASPPMSPSATPPPQAPPPL--------AAPPLQLAKPPPQAP--------------- 481

Query: 515 YLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVAL 574
                 P   T P  A   P   PA+  GQ         A   PS S P+          
Sbjct: 482 ------PALATPPLQALPSP---PASFPGQ---------APFSPSASLPMS--------- 514

Query: 575 DLSVRKPTAEASPVKASRSVE-----HAKPTA-AMDVPDVGNMVSDLPGLKKIDTEAPGL 628
              +  P  +A PV A+  ++      A PT  A   P      + + G +     APG 
Sbjct: 515 --PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 572

Query: 629 PGVPV----TTDAMPRTNFHSSVAFMF-RKFKILRPAPLPAAVVPSTPTSAPAPTQPA-- 681
           P  P     +T + P    HSS A     + +     P   A     P +  A   PA  
Sbjct: 573 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 632

Query: 682 ---PTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPA--PSPAPARAQAPA 736
              P P   P+  R     PL         P PPA    S         +  P  A    
Sbjct: 633 SRGPAP---PLAFRGAPGAPL---------PWPPATGPGSADGLCTIYETEGPESATPAP 680

Query: 737 SARDPAPAPAPVAGPAPASTSAPGDS 762
            A DP P+P    G A A   A   S
Sbjct: 681 GALDPGPSPGTSGGKAAAGAGAGASS 706



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 145/558 (25%), Positives = 190/558 (34%), Gaps = 84/558 (15%)

Query: 114 PFSPQAHSYP---GPPLAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWTLATGPLL--P 168
           P S  A S P   G P A   P    P   GL           P   D   A GPL   P
Sbjct: 239 PLSSPARSGPSARGTPRAPAHPSQPKPK--GLQALRPPQVT--PPRKDAAPALGPLSSSP 294

Query: 169 SADPPCSLAPAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLAS 228
            A P  S  P+PS   +L     + +P+  ++  S  + S   P L   Q  HS  FL S
Sbjct: 295 LATPSPSAPPSPSAPPSL-----QTLPSPPATPPSQATTSLGSPTL---QATHS--FLPS 344

Query: 229 RYTGPYPRNSKQA--------MSEGPSSPWTQLAQPLGPPCQDTG---PTHY-PPPHHPP 276
               P      QA        +   PS P +    PL  P          H    P  PP
Sbjct: 345 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404

Query: 277 PHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQAPYIP 336
           P PP   P  P    P    +  P+                  L +P L Q     P  P
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPS-------------QAPPSLAAPPL-QVPPSPPASP 450

Query: 337 PLGLDAYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGG 396
           P+   A P P AP P  +P L+L  P  P+     AP  L+ P  +   S   + PG   
Sbjct: 451 PMSPSATPPPQAPPPLAAPPLQLAKP-PPQ-----APPALATPPLQALPSPPASFPGQAP 504

Query: 397 TPPSQN---NVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPR 453
             PS +   +  A P P A      PL    P S P  P  +A  +   P        P 
Sbjct: 505 FSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPPASPTLQAPRRPPTPG-------PD 556

Query: 454 LSEHSGPPIVIRDSPVPCTPPALPPCA---------RECQSLPQKEDARPPSSPP----- 499
            S  SGP + +  +P P  PP+  P +             +    E+ R   S P     
Sbjct: 557 TSV-SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAA 615

Query: 500 -MPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGP 558
             P  D   +      +   PAP            P   PAT  G   G   T+   EGP
Sbjct: 616 ASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP-WPPATGPGSADGLC-TIYETEGP 673

Query: 559 SGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAK----PTAAMDVPDVGNMVSD 614
             + P  G+L    +   S  K  A A    +SRS + A+    P  A+    V +++S 
Sbjct: 674 ESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSR 733

Query: 615 LPGLKKIDTEAPGLPGVP 632
              L   +  A G  G P
Sbjct: 734 TLLLAAAEGAAGGSGGGP 751



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 112/508 (22%), Positives = 174/508 (34%), Gaps = 69/508 (13%)

Query: 287 PACRHPEKQGSYSPALPLQPLG----------GHKGTGYQAGGLGSPYLRQQAAQAPYI- 335
           P    P   GS  P  P+ P            G K    +AGG+G   + + A +A    
Sbjct: 22  PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81

Query: 336 ---PPLGLDAYPYPSAPLPAPSP--------GLKLEPPLTPRCPLDFAPQTLSFPYA--- 381
              PP        P A   +P P        G     PL  +     A +T++   A   
Sbjct: 82  TSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA 141

Query: 382 --RDDLSLYGASPGLGGTP--PSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAE 437
             R  LS        G TP  PS    R     G      +P P+++P     RP  E  
Sbjct: 142 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP-----RPPTEGP 196

Query: 438 EKTWLPSCRKEKLQPRLSEHSGPPI---VIRDSPVPCTPPALPPCARECQSLPQKEDARP 494
            K+   +      +P  +    P     + R +    +  A P  +        +   R 
Sbjct: 197 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 256

Query: 495 PSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPA 554
           P+ P  P    + +L P +  +  P  +A       ++ P + P+ S         +L  
Sbjct: 257 PAHPSQPKPKGLQALRPPQ--VTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQT 314

Query: 555 QEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSD 614
              P  + P + +         S+  PT     ++A+ S   + P + +  P        
Sbjct: 315 LPSPPATPPSQATT--------SLGSPT-----LQATHSFLPSPPLSPLATPPP----QA 357

Query: 615 LPGLKKIDTEAPGLPGV--PVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPT 672
            P L     +AP  P    P++  A P     +++A    +     P P P    P +P 
Sbjct: 358 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF-SPPPSPPVQAPFSPP 416

Query: 673 SAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARA 732
           ++P  +  A  P+  P  L   A  PL V       PSPPA    SP+  P P   P  A
Sbjct: 417 ASPPVSPSATPPSQAPPSL---AAPPLQVP------PSPPASPPMSPSATPPPQAPPPLA 467

Query: 733 QAPAS-ARDPAPAPAPVAGPAPASTSAP 759
             P   A+ P  AP  +A P   +  +P
Sbjct: 468 APPLQLAKPPPQAPPALATPPLQALPSP 495



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 35/118 (29%), Positives = 47/118 (39%), Gaps = 17/118 (14%)

Query: 929  DTEAGAVSSSEPTVAR-DEPESLALAQKSPAPKVRKPGRKPPTPGPEKAEAAAGEESCGA 987
            DT      +  P +AR        +    PAP  R    +PPT GP K+ ++A E S   
Sbjct: 154  DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP---RPPTEGPRKSVSSASEHST-T 209

Query: 988  SPTPATSASPP--GPTLKARFRSLLETAWLNGLALPTWGHKSSR--------PDQPSP 1035
             P+PA    P   G   +   RSL  +A    L+ P     S+R        P QP P
Sbjct: 210  EPSPAARRRPSAGGGLQRPASRSLSSSA--TPLSSPARSGPSARGTPRAPAHPSQPKP 265


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 124/471 (26%), Positives = 170/471 (36%), Gaps = 102/471 (21%)

Query: 348  APLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNN---- 403
            AP P P+P + + P  TP      AP  LS P A + +            PP+  N    
Sbjct: 1264 APTPGPTP-VSVLPSSTPSTTP--APTGLSLPLAANQV------------PPTMVNNTGV 1308

Query: 404  ----VRAVPQPGAFQRACQPLPASQPCSEPVR---PAQEAEEKTWLPSCRKEKLQPRLSE 456
                VR  P+ G       P+P   P   P     PA      T  P        P L  
Sbjct: 1309 VKIVVRQAPRDGL-----TPVPPLAPAPRPPSSGLPAVLNPRPTLTPG---RLPTPTLGT 1360

Query: 457  HSGP---PIVIRD------SPVPCTPPALPPCARECQSLPQKEDAR--PPSSPPMPVIDN 505
               P   P ++R       SP P    + P  A    S P    +    P+S PMP+ ++
Sbjct: 1361 ARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNS 1420

Query: 506  VFSLAPYRDYLDVPAPEA------TTEPDSATAE---PDSAPATSEGQDKGCRGTL---- 552
                +P    + VP   +      TT P  A+A    P SAP T          ++    
Sbjct: 1421 SPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPL 1480

Query: 553  ----PAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDV 608
                PA  GP    P  G+     AL L +    A A  + +S++  H    A       
Sbjct: 1481 APVVPAAPGPPSLAP-SGASPSASALTLGL----ATAPSLSSSQTPGHPLLLAPTS---- 1531

Query: 609  GNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPA-------- 660
                S +PGL    T AP    V V   A+  + F S+      +  +L PA        
Sbjct: 1532 ----SHVPGLNS--TVAPACSPVLVPASALA-SPFPSAPNPAPAQASLLAPASSASQALA 1584

Query: 661  -PLPAAVVPSTPTSAPAPTQP-------APTPTSGPIGLRILAQQPLSVTCFSLALPSPP 712
             PL     P T   AP+P  P       AP+P + P+    LA     V   + +     
Sbjct: 1585 TPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPV----LASSQTPVPVMAPSSTPGT 1640

Query: 713  AVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSL 763
            ++A ASP PAP P  AP+  Q       PAP P+P+  PA   T A   +L
Sbjct: 1641 SLASASPVPAPTPVLAPSSTQTML----PAPVPSPLPSPASTQTLALAPAL 1687



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 164/709 (23%), Positives = 219/709 (30%), Gaps = 155/709 (21%)

Query: 96   SPAEGPEKMQDSSPVELLPFSPQAHSYPGPPLAAPKPVYRNPLCYGLSTCLGEGAVK--- 152
            +P  GP      +PV +LP S  + +     L+ P    + P     +T    G VK   
Sbjct: 1264 APTPGP------TPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNT----GVVKIVV 1313

Query: 153  RPLDVDWTLATGPLLPSADPPCSLAPAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQP 212
            R    D      PL P+  PP S  PA    +          P  G+++    + +  +P
Sbjct: 1314 RQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRP 1373

Query: 213  FLEKYQTIHSTGFLASRYTGPYPRNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPP 272
             L+    +HS          P P  S  A    P +    ++ PL  P    GP   P P
Sbjct: 1374 LLK---LVHS----------PSPEVSASAPGAAPLT----ISSPLHVPSSLPGPASSPMP 1416

Query: 273  HHPPPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQA 332
               P   P A P       P      S +LP+                  P      A A
Sbjct: 1417 I--PNSSPLASPVSSTVSVP-----LSSSLPISV----------------PTTLPAPASA 1453

Query: 333  PYIPPLGLDAYPYPSAPLPAPSPGLKL----EPPLTPRCPLDFAPQTLSFPYARDDLSLY 388
            P   P+        SAPL   + G  L     PPL P  P                    
Sbjct: 1454 PLTIPI--------SAPLTVSASGPALLTSVTPPLAPVVP-------------------- 1485

Query: 389  GASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKE 448
             A+PG    PPS     A P   A        P+      P  P   A   + +P     
Sbjct: 1486 -AAPG----PPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNST 1540

Query: 449  KLQPRLSEHSGP------PIVIRDSPVPCTPPALPPCARECQSL---------PQKEDAR 493
             + P  S    P      P     +P P     L P +   Q+L         PQ     
Sbjct: 1541 -VAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILA 1599

Query: 494  PPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEP---DSATAEPDSAPATSEGQDKGCRG 550
            P  +PP         LAP    L V AP     P    S T  P  AP+++ G       
Sbjct: 1600 PSPAPP---------LAP----LPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASAS 1646

Query: 551  TLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPD--- 607
             +PA        P+      +  L   V  P    +  +         PT     P    
Sbjct: 1647 PVPAPT------PVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTL 1700

Query: 608  ---VGNMVSDLPGLKKIDTEAPGLPGVPVTTDAM-PRTNFHSSVAFMFRKFKILRPA--- 660
                GN     P      T A  L   P  T ++ P      +          L PA   
Sbjct: 1701 SLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPV 1760

Query: 661  -PLPAAVVPSTPTS------APAPTQ-----PAPTPTSGPIGLRILAQQPLSVTCFSLAL 708
             P PA  +   P S      APA  Q     PAP PT GP   + LA  P S        
Sbjct: 1761 GPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQS----- 1815

Query: 709  PSPPAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTS 757
            P+  A ++   A   AP P    ++ P S  +P         P+P ST+
Sbjct: 1816 PASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTA 1864



 Score = 63.9 bits (154), Expect = 7e-10
 Identities = 148/611 (24%), Positives = 193/611 (31%), Gaps = 132/611 (21%)

Query: 262  QDTGPTHYPPPHHP-PPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAGGL 320
            Q   PT  P P    P   P   P P     P       P + +   G  K    QA   
Sbjct: 1261 QAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTM-VNNTGVVKIVVRQAPRD 1319

Query: 321  GSPYLRQQAAQAPYIPPLGLDAY--PYPSAP---LPAPSPGLKLEPPLTPRCPLDFAPQT 375
            G   +    A AP  P  GL A   P P+     LP P+ G    P  TP          
Sbjct: 1320 GLTPV-PPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLV 1378

Query: 376  LSFPYARDDLSLYGASPGLGGTP---PSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRP 432
             S P      S  GA+P    +P   PS     ++P P +   +  P+P S P + PV  
Sbjct: 1379 HS-PSPEVSASAPGAAPLTISSPLHVPS-----SLPGPAS---SPMPIPNSSPLASPVSS 1429

Query: 433  AQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDA 492
                   + LP              S P  +   +  P T P   P              
Sbjct: 1430 TVSVPLSSSLPI-------------SVPTTLPAPASAPLTIPISAPLTVSASGPALLTSV 1476

Query: 493  RPPSSPPMPVIDNVFSLAPYRDYLDVPAPEAT-------TEPDSATAEPDSAP---ATSE 542
             PP +P +P      SLAP        +P A+       T P  ++++    P   A + 
Sbjct: 1477 TPPLAPVVPAAPGPPSLAP-----SGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTS 1531

Query: 543  GQDKGCRGTLPAQEGP-----SGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHA 597
                G   T+     P     S       S         S+  P + AS   A+     A
Sbjct: 1532 SHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMA 1591

Query: 598  KPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPG----VPVTT-DAMPRTNFHSSVAFMFR 652
             P  A+  P     ++ LP L      AP L      VPV    + P T+  S+      
Sbjct: 1592 APQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPV--- 1648

Query: 653  KFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQP-------------- 698
                  PAP P     ST T  PAP    P+P   P   + LA  P              
Sbjct: 1649 ------PAPTPVLAPSSTQTMLPAPV---PSPLPSPASTQTLALAPALAPTLGGSSPSQT 1699

Query: 699  ----------------LSVTCFSLALPSPPAVAVASPAP----------APAPSPAPARA 732
                            LS+T  S  +P+P      +P P          APAP  APA  
Sbjct: 1700 LSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASP 1759

Query: 733  QAPASARD--------------PA--------PAPAPVAGPAPASTSAPGDSLEQHFTGL 770
              PA A                PA        PAP P  GPA A T A   +  Q     
Sbjct: 1760 VGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQ 1819

Query: 771  HASLCDAISGS 781
             +SL  + SG+
Sbjct: 1820 ASSLVVSASGA 1830



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 153/638 (23%), Positives = 216/638 (33%), Gaps = 99/638 (15%)

Query: 116  SPQAHSYPGPPLAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWTLATGPLLPSADPPCS 175
            +P+    P PPLA P P    P   GL   L      RP     TL  G L     P   
Sbjct: 1316 APRDGLTPVPPLA-PAP---RPPSSGLPAVLNP----RP-----TLTPGRL---PTPTLG 1359

Query: 176  LAPAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYP 235
             A AP    TL    L+ V     S + S S     P L     +H    L    + P P
Sbjct: 1360 TARAPMPTPTLVRPLLKLV--HSPSPEVSASAPGAAP-LTISSPLHVPSSLPGPASSPMP 1416

Query: 236  RNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQ 295
              +   ++   SS    ++ PL      + PT  P P   P   P + P   +   P   
Sbjct: 1417 IPNSSPLASPVSST---VSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALL 1473

Query: 296  GSYSPAL-PLQPLG-GHKGTGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAP 353
             S +P L P+ P   G            +  L    A AP +       +P   AP  + 
Sbjct: 1474 TSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSH 1533

Query: 354  SPGLKLEPPLTPRC-PLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGA 412
             PGL     + P C P+      L+ P+           P      P+Q ++ A P   A
Sbjct: 1534 VPGLN--STVAPACSPVLVPASALASPF-----------PSAPNPAPAQASLLA-PASSA 1579

Query: 413  FQRACQPL-PASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPC 471
             Q    PL P + P +  + P+         P      L P  S  + P +    +PVP 
Sbjct: 1580 SQALATPLAPMAAPQTAILAPSPAP------PLAPLPVLAP--SPGAAPVLASSQTPVPV 1631

Query: 472  TPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSAT 531
              P+  P      +         P   P PV      LAP      +PAP  +  P  A+
Sbjct: 1632 MAPSSTPGTSLASA--------SPVPAPTPV------LAPSSTQTMLPAPVPSPLPSPAS 1677

Query: 532  AEPDS-APATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKA 590
             +  + APA +        G+ P+Q    G+   +G              PT   S   A
Sbjct: 1678 TQTLALAPALAPTLG----GSSPSQTLSLGTGNPQGPF------------PTQTLSLTPA 1721

Query: 591  SRSVEHAKPTAAMDV-PDVG-NMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVA 648
            S  V     T ++   P +G      L     +   +P  P    T    P ++  S +A
Sbjct: 1722 SSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLA 1781

Query: 649  FMFRKFKILRPAPLPAA--VVPSTPTSAPAPTQP---------------APTPTSGPIGL 691
                +   L PAP+P        T   APA TQ                AP P +    L
Sbjct: 1782 PASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRL 1841

Query: 692  RILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAP 729
             +   +P ++T  S   PSPP+ A +   P P   P P
Sbjct: 1842 PVSKDEPDTLTLRS-GPPSPPSTATSFGGPRPRRQPPP 1878



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 156/612 (25%), Positives = 211/612 (34%), Gaps = 97/612 (15%)

Query: 232  GPYPR--NSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPAC 289
            GP P+   +   +S  P+ P      PL P  +  GP   PP        PQ LP P   
Sbjct: 1039 GPVPQVLPASLMVSASPAGP------PLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGV 1092

Query: 290  RHPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQAP--YIPPLGLDAYPYPS 347
                 +   +P L L+P          A   GS  L +     P    PP         +
Sbjct: 1093 LSGTSRPP-TPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTT 1151

Query: 348  AP-----LPAPSPG---LKLEPPLTPRCP------------LDFAP-------QTLSFPY 380
            A      +PAP+P    L L P +  R P            L   P       + L+F  
Sbjct: 1152 ATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQI 1211

Query: 381  ARDDLSLYGASP---GLGGTPPSQNNV----------RAVPQPG--AFQRACQPLPASQP 425
              + L+L GA      +G   P Q NV            + QP   A  +A  P P   P
Sbjct: 1212 QGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTP 1271

Query: 426  CSE-PVRPAQEAEEKTWLP-SCRKEKLQPRLSEHSGP-PIVIRDSPVPCTPPALPPCARE 482
             S  P          T L       ++ P +  ++G   IV+R +P     P +PP A  
Sbjct: 1272 VSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTP-VPPLAPA 1330

Query: 483  CQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSE 542
                      RPPSS    V++   +L P R    +P P   T        P   P    
Sbjct: 1331 ---------PRPPSSGLPAVLNPRPTLTPGR----LPTPTLGT-----ARAPMPTPTLVR 1372

Query: 543  GQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAA 602
               K      P     S S P    L     L +    P   +SP+    S   A P ++
Sbjct: 1373 PLLKLVHSPSPEV---SASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSS 1429

Query: 603  -MDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTD-AMPRTNFHSSVAFMFRKFKILRPA 660
             + VP    + S LP    + T  P     P+T   + P T   S  A +      L P 
Sbjct: 1430 TVSVP----LSSSLP--ISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPV 1483

Query: 661  PLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFS--LALPSPPAVAVAS 718
             +PAA  P  P+ AP+   P+ +  +  +GL        S T     L  P+   V   +
Sbjct: 1484 -VPAA--PGPPSLAPSGASPSASALT--LGLATAPSLSSSQTPGHPLLLAPTSSHVPGLN 1538

Query: 719  PAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQHFTGLHASLCDAI 778
               APA SP    A A AS    AP PAP    A AS  AP  S  Q      A +    
Sbjct: 1539 STVAPACSPVLVPASALASPFPSAPNPAP----AQASLLAPASSASQALATPLAPMAAPQ 1594

Query: 779  SGSVAHSPPEKL 790
            +  +A SP   L
Sbjct: 1595 TAILAPSPAPPL 1606



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 36/110 (32%), Positives = 49/110 (44%), Gaps = 12/110 (10%)

Query: 655  KILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAV 714
            ++ RPAP P     S P + PA     P P S P+   I A  P+++    + LPSPP  
Sbjct: 2435 RVPRPAPRPRPTPASAPAAIPALV---PVPVSAPVP--ISAPNPITILPVHI-LPSPPPP 2488

Query: 715  AVASPAPAPAPSPAPARAQAPASARDPA------PAPAPVAGPAPASTSA 758
            +   P  +PA +P PA    PA    PA      P+   + GP     SA
Sbjct: 2489 SQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISA 2538



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 125/577 (21%), Positives = 182/577 (31%), Gaps = 109/577 (18%)

Query: 246  PSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQ 305
            PS P      P   P     P   PPP H PP     L  P +   P   G   P++P+ 
Sbjct: 2483 PSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSS---PLLLG--PPSVPIS 2537

Query: 306  ------PLGGHKGTGYQAGGLGSPYLRQQAAQA-------PYIPPLGLDAYPYPSAP--- 349
                  PLG        A  L SP   + A+ A         +PP  L        P   
Sbjct: 2538 ASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSE 2597

Query: 350  ----LPAPSPGLKLEPPLTPRCPLDFAPQ-----TLSFPYARDDLSLYGASPGLGGTPPS 400
                L   +P L LE    P      AP      TL+     ++L L  +       PPS
Sbjct: 2598 KNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPS 2657

Query: 401  QNNVRAVPQPGAFQRACQPL-PASQPCSEPVRPAQEAEEKTWLPSCRKEKL-QPRLSEHS 458
              +   + +P    R  + L  A  P S P +P +    +   PS        P     +
Sbjct: 2658 AASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPA 2717

Query: 459  GPPIVIRDSPVPCT-----PPALPPCARECQSLP--------------QKEDARPPSSPP 499
             PP     + V         P  PP  +  + LP              ++   R  +S  
Sbjct: 2718 RPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTL 2777

Query: 500  MPVIDNVFSLAPYRDYLDVPAPEAT--------TEPDSATAEPDSAP----------ATS 541
            +P +    +         +  PE++          P S+   P   P           T 
Sbjct: 2778 VPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTG 2837

Query: 542  EGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHA---- 597
             G  +   G L A   P   K  RG            R P    SP  A R V+ A    
Sbjct: 2838 GGSPENGDGALLAIT-PPAVKRRRG------------RPPKKNRSPADAGRGVDEAPSST 2884

Query: 598  ---KPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPG-VPVTTDAMPRTNFHSSVAFMFRK 653
               K   A  VP    ++   P L     E   +PG  P+    + R N   S     R+
Sbjct: 2885 LKGKTNGADPVPGPETLIVADPVL-----EPQLIPGPQPLGPQPVHRPNPLLSPVEKRRR 2939

Query: 654  FK--ILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSP 711
             +    R  P+P  +  +   ++ + TQP P P+        L   P  + C +  + + 
Sbjct: 2940 GRPPKARDLPIPGTISSAGDGNSESRTQPPPHPSP-------LTPLPPLLVCPTATVANT 2992

Query: 712  PAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPV 748
                  S +P     P   R + P +   P P+  PV
Sbjct: 2993 VTTVTISTSP-----PKRKRGRPPKNPPSPRPSQLPV 3024



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 20/44 (45%), Positives = 23/44 (52%)

Query: 710  SPPAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAP 753
            SP    V  PAP P P+PA A A  PA    P  AP P++ P P
Sbjct: 2430 SPARERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNP 2473



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 32/99 (32%), Positives = 39/99 (39%), Gaps = 9/99 (9%)

Query: 674  APAPTQPAPTPTSGPIGLRILAQ----QPLSVTCFSLALPSPPAVAVASPAPAPAPSPAP 729
            A AP +P    +    G R   Q     P+     + +  +PP     SPA    P PAP
Sbjct: 2385 AKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPR---CSPARERVPRPAP 2441

Query: 730  ARAQAPASARDPAPA--PAPVAGPAPASTSAPGDSLEQH 766
                 PASA    PA  P PV+ P P S   P   L  H
Sbjct: 2442 RPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVH 2480



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 13/103 (12%)

Query: 940  PTVARDEPESLALAQKSPAPKVRKPGRKPPTPGPEKAEAAAGEESCGASPTPATSASP-- 997
            P+ A DEP    L     + ++ +   K PT  PEK +     E    S + + ++SP  
Sbjct: 2656 PSAASDEPLQEPLEADRTSEELTEA--KTPTSSPEKPQELVTAEVAAPSTSSSATSSPEG 2713

Query: 998  PGPTLKARFRSLLETAWLNGLALPTWGHKSSRPDQPSPCPQLL 1040
            P P    R R+  +        +   G  + RP QP P P++L
Sbjct: 2714 PSPARPPRRRTSAD--------VEIRGQGTGRPGQP-PGPKVL 2747


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 116/445 (26%), Positives = 159/445 (35%), Gaps = 104/445 (23%)

Query: 168 PSADPPCSLAPAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLA 227
           PS+ PP      P+ G T   T    VP +GS   S     P  P               
Sbjct: 197 PSSAPP-GTPQLPTPGPTPSAT---AVPPQGSPTASQAPNQPQAP--------------- 237

Query: 228 SRYTGPYPRNS-KQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPP------ 280
              T P P    +QA +  P  P                P+ +PPPH P PHPP      
Sbjct: 238 ---TAPVPHTHIQQAPALHPQRP----------------PSPHPPPH-PSPHPPLQPLTG 277

Query: 281 -QALPCPPACRHPEKQGSYSP---ALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQAPYIP 336
               P  P+   P   G   P   +L   PL  H G     G      L  QA+Q     
Sbjct: 278 SAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFG------LPPQASQGQ--A 329

Query: 337 PLGLD---AYPYPSAPLPAPSPGLKLEPPLTPR-CPLDFAPQTLSFPYARDDLSLYGASP 392
           PLG     AYP+ S  LPA    L+ + P  PR  PL  AP  L+ P+ +          
Sbjct: 330 PLGTSPAAAYPHTSLQLPASQSALQSQQP--PREQPLPPAP--LAMPHIK---------- 375

Query: 393 GLGGTPPSQNNVRAVPQPGAFQ---RACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEK 449
                PP    +  +P P A +       P P S   + P  PA +       P      
Sbjct: 376 -----PPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALK-------PLSSLST 423

Query: 450 LQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSL 509
             P  +      ++ +  P+P + PA PP   + Q+LP      PP+S P   +  V   
Sbjct: 424 HHPPSAHPPPLQLMPQSQPLP-SSPAQPPGLTQSQNLPP-----PPASHPPTGLHQVAPQ 477

Query: 510 APYRDYLDVPA--PEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSG--SKPLR 565
            P+  +  VP   P  T     +T+ P + P TS      C G   +    +G  S PL 
Sbjct: 478 PPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTS--AQPPCSGAAASGGSIAGGSSCPLP 535

Query: 566 GSLKEEVALDLSVRKPTAEASPVKA 590
               +E ALD    +P +   P ++
Sbjct: 536 TVQIKEEALD-DAEEPESPPPPPRS 559



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 137/548 (25%), Positives = 178/548 (32%), Gaps = 141/548 (25%)

Query: 228 SRYTGPYPRNSKQAMSEGPSSPWTQLAQPLGPPCQ-DTGPTHYPPPHHPPPHPPQAL--- 283
           +R T P   + +   S+  SS   Q+ Q   P  Q  TG T  P P   PP  PQ     
Sbjct: 154 NRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVT--PAPSSAPPGTPQLPTPG 211

Query: 284 PCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQA--PYIPPLGLD 341
           P P A   P +    +   P QP         QA     P+   Q A A  P  PP    
Sbjct: 212 PTPSATAVPPQGSPTASQAPNQP---------QAPTAPVPHTHIQQAPALHPQRPPS--- 259

Query: 342 AYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQ 401
             P+P  P P+P P L+   PLT       AP              +   P  G  PP  
Sbjct: 260 --PHPP-PHPSPHPPLQ---PLTGSAGQPSAPS-------------HAQPPLHGQGPPGP 300

Query: 402 NNVRAVP---QPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHS 458
           ++++A P    PG  Q    P  ASQ  +        A   T   S +    Q  L    
Sbjct: 301 HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT---SLQLPASQSALQSQQ 357

Query: 459 GPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDV 518
            P    R+ P+P  P A+P               +PP + P+P                +
Sbjct: 358 PP----REQPLPPAPLAMP-------------HIKPPPTTPIP---------------QL 385

Query: 519 PAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSV 578
           PAP+A   P          P  S          LP    P   KPL           LS 
Sbjct: 386 PAPQAHKHP----------PHLSGPSPFSMNANLPP---PPALKPLSS---------LST 423

Query: 579 RKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAM 638
             P +   P           P++    P +              T++  LP  P +    
Sbjct: 424 HHPPSAHPPPLQLMPQSQPLPSSPAQPPGL--------------TQSQNLPPPPASH--- 466

Query: 639 PRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPA-PTPTSGPIGLRILAQQ 697
           P T  H            + P P P A  P  P   P  T P  P+ ++ P G    AQ 
Sbjct: 467 PPTGLHQ-----------VAPQP-PFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514

Query: 698 PLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARAQAPASARDPAPAPAPVAG 750
           P S      A  S  ++A  S  P P       A   A      P   R P+P P  V  
Sbjct: 515 PCSG-----AAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDT 569

Query: 751 PAPASTSA 758
           P+ AS SA
Sbjct: 570 PSHASQSA 577



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 100/441 (22%), Positives = 128/441 (29%), Gaps = 84/441 (19%)

Query: 357 LKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRA 416
           L+ +PP   + P    P   S P     L   G +P     PP Q +  A   P   Q  
Sbjct: 180 LQAQPPAL-QAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPP-QGSPTASQAPNQPQAP 237

Query: 417 CQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPAL 476
             P+P +     P                    L P+      PP      P P   P L
Sbjct: 238 TAPVPHTHIQQAPA-------------------LHPQRPPSPHPP------PHPSPHPPL 272

Query: 477 PPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDS 536
            P             A+PP     P   +     P   +   P P               
Sbjct: 273 QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP----------- 321

Query: 537 APATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEH 596
            P  S+GQ     GT PA   P  S  L  S        L  ++P  E     A  ++ H
Sbjct: 322 -PQASQGQAP--LGTSPAAAYPHTSLQLPASQSA-----LQSQQPPREQPLPPAPLAMPH 373

Query: 597 AKPTAAMDVPDVGNMVSD-----LPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMF 651
            KP     +P +    +      L G       A  LP  P        +  H   A   
Sbjct: 374 IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNA-NLPPPPALKPLSSLSTHHPPSA--- 429

Query: 652 RKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSP 711
                  P PL        P S P P+ PA  P         L Q        S  LP P
Sbjct: 430 ------HPPPLQLM-----PQSQPLPSSPAQPPG--------LTQ--------SQNLPPP 462

Query: 712 PAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQHFTGLH 771
           PA     P      +P P  AQ P     P P   P         + PG S +   +G  
Sbjct: 463 PASH--PPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAA 520

Query: 772 ASLCDAISGSVAHSPPEKLRE 792
           AS      GS    P  +++E
Sbjct: 521 ASGGSIAGGSSCPLPTVQIKE 541



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 86/324 (26%), Positives = 114/324 (35%), Gaps = 61/324 (18%)

Query: 67  TPYPPLYS-TGMAGPPLQADNLLTNCLFYRSPAEGPEKMQDSSPVELLPFSPQAHSYPGP 125
           +P+PPL   TG AG P  A +     L  + P  GP  +Q + P+   P  PQ    P  
Sbjct: 267 SPHPPLQPLTGSAGQP-SAPSHAQPPLHGQGPP-GPHSLQ-AGPLLQHPGPPQPFGLPPQ 323

Query: 126 PLAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWTLATGPLLPSADPPCSLAPAPSKGQT 185
                 P+  +P      T L   A +  L         PL P+      + P P+    
Sbjct: 324 ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT---- 379

Query: 186 LDGTFLRGVPA----------EGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYP 235
              T +  +PA           G S  S  +  P  P L+   ++ ST    S +  P P
Sbjct: 380 ---TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL-STHHPPSAH--PPP 433

Query: 236 RNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQ 295
                     PSSP    AQP G       P   PP  HPP    Q  P PP  +HP   
Sbjct: 434 LQLMPQSQPLPSSP----AQPPGLTQSQNLPP--PPASHPPTGLHQVAPQPPFAQHPFVP 487

Query: 296 GSYSPALP----------------LQP--LGGHKGTGYQAGGLGSP----YLRQQA---A 330
           G   P  P                 QP   G     G  AGG   P     ++++A   A
Sbjct: 488 GGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDA 547

Query: 331 QAPYIPPLGLDAYPYPSAPLPAPS 354
           + P  PP      P P +P P P+
Sbjct: 548 EEPESPP------PPPRSPSPEPT 565



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 64/252 (25%), Positives = 88/252 (34%), Gaps = 52/252 (20%)

Query: 514 DYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVA 573
           D  D+     +T P   + + + + + S  Q +  +   PA + P+G  P   S      
Sbjct: 146 DPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP 205

Query: 574 LDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPV 633
             L    PT  A+ V    S     PTA                     ++AP  P  P 
Sbjct: 206 -QLPTPGPTPSATAVPPQGS-----PTA---------------------SQAPNQPQAP- 237

Query: 634 TTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTP-------TSAPAPTQPAPTPTS 686
            T  +P T+   + A   ++     P P P+   P  P        SAP+  QP P    
Sbjct: 238 -TAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQP-PLHGQ 295

Query: 687 GPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAPAPA 746
           GP G   L   PL      L  P PP      P   P   P  ++ QAP     PA A  
Sbjct: 296 GPPGPHSLQAGPL------LQHPGPP-----QPFGLP---PQASQGQAPLGT-SPAAAYP 340

Query: 747 PVAGPAPASTSA 758
             +   PAS SA
Sbjct: 341 HTSLQLPASQSA 352


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 116/445 (26%), Positives = 159/445 (35%), Gaps = 104/445 (23%)

Query: 168  PSADPPCSLAPAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLA 227
            PS+ PP      P+ G T   T    VP +GS   S     P  P               
Sbjct: 751  PSSAPP-GTPQLPTPGPTPSAT---AVPPQGSPTASQAPNQPQAP--------------- 791

Query: 228  SRYTGPYPRNS-KQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPP------ 280
               T P P    +QA +  P  P                P+ +PPPH P PHPP      
Sbjct: 792  ---TAPVPHTHIQQAPALHPQRP----------------PSPHPPPH-PSPHPPLQPLTG 831

Query: 281  -QALPCPPACRHPEKQGSYSP---ALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQAPYIP 336
                P  P+   P   G   P   +L   PL  H G     G      L  QA+Q     
Sbjct: 832  SAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFG------LPPQASQGQ--A 883

Query: 337  PLGLD---AYPYPSAPLPAPSPGLKLEPPLTPR-CPLDFAPQTLSFPYARDDLSLYGASP 392
            PLG     AYP+ S  LPA    L+ + P  PR  PL  AP  L+ P+ +          
Sbjct: 884  PLGTSPAAAYPHTSLQLPASQSALQSQQP--PREQPLPPAP--LAMPHIK---------- 929

Query: 393  GLGGTPPSQNNVRAVPQPGAFQ---RACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEK 449
                 PP    +  +P P A +       P P S   + P  PA +       P      
Sbjct: 930  -----PPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALK-------PLSSLST 977

Query: 450  LQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSL 509
              P  +      ++ +  P+P + PA PP   + Q+LP      PP+S P   +  V   
Sbjct: 978  HHPPSAHPPPLQLMPQSQPLP-SSPAQPPGLTQSQNLPP-----PPASHPPTGLHQVAPQ 1031

Query: 510  APYRDYLDVPA--PEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSG--SKPLR 565
             P+  +  VP   P  T     +T+ P + P TS      C G   +    +G  S PL 
Sbjct: 1032 PPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTS--AQPPCSGAAASGGSIAGGSSCPLP 1089

Query: 566  GSLKEEVALDLSVRKPTAEASPVKA 590
                +E ALD    +P +   P ++
Sbjct: 1090 TVQIKEEALD-DAEEPESPPPPPRS 1113



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 137/548 (25%), Positives = 178/548 (32%), Gaps = 141/548 (25%)

Query: 228  SRYTGPYPRNSKQAMSEGPSSPWTQLAQPLGPPCQ-DTGPTHYPPPHHPPPHPPQAL--- 283
            +R T P   + +   S+  SS   Q+ Q   P  Q  TG T  P P   PP  PQ     
Sbjct: 708  NRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVT--PAPSSAPPGTPQLPTPG 765

Query: 284  PCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQA--PYIPPLGLD 341
            P P A   P +    +   P QP         QA     P+   Q A A  P  PP    
Sbjct: 766  PTPSATAVPPQGSPTASQAPNQP---------QAPTAPVPHTHIQQAPALHPQRPPS--- 813

Query: 342  AYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQ 401
              P+P  P P+P P L+   PLT       AP              +   P  G  PP  
Sbjct: 814  --PHPP-PHPSPHPPLQ---PLTGSAGQPSAPS-------------HAQPPLHGQGPPGP 854

Query: 402  NNVRAVP---QPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHS 458
            ++++A P    PG  Q    P  ASQ  +        A   T   S +    Q  L    
Sbjct: 855  HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT---SLQLPASQSALQSQQ 911

Query: 459  GPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDV 518
             P    R+ P+P  P A+P               +PP + P+P                +
Sbjct: 912  PP----REQPLPPAPLAMP-------------HIKPPPTTPIP---------------QL 939

Query: 519  PAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSV 578
            PAP+A   P          P  S          LP    P   KPL           LS 
Sbjct: 940  PAPQAHKHP----------PHLSGPSPFSMNANLPP---PPALKPLSS---------LST 977

Query: 579  RKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAM 638
              P +   P           P++    P +              T++  LP  P +    
Sbjct: 978  HHPPSAHPPPLQLMPQSQPLPSSPAQPPGL--------------TQSQNLPPPPASH--- 1020

Query: 639  PRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPA-PTPTSGPIGLRILAQQ 697
            P T  H            + P P P A  P  P   P  T P  P+ ++ P G    AQ 
Sbjct: 1021 PPTGLHQ-----------VAPQP-PFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 1068

Query: 698  PLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARAQAPASARDPAPAPAPVAG 750
            P S      A  S  ++A  S  P P       A   A      P   R P+P P  V  
Sbjct: 1069 PCSG-----AAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDT 1123

Query: 751  PAPASTSA 758
            P+ AS SA
Sbjct: 1124 PSHASQSA 1131



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 100/441 (22%), Positives = 128/441 (29%), Gaps = 84/441 (19%)

Query: 357  LKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRA 416
            L+ +PP   + P    P   S P     L   G +P     PP Q +  A   P   Q  
Sbjct: 734  LQAQPPAL-QAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPP-QGSPTASQAPNQPQAP 791

Query: 417  CQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPAL 476
              P+P +     P                    L P+      PP      P P   P L
Sbjct: 792  TAPVPHTHIQQAPA-------------------LHPQRPPSPHPP------PHPSPHPPL 826

Query: 477  PPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDS 536
             P             A+PP     P   +     P   +   P P               
Sbjct: 827  QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP----------- 875

Query: 537  APATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEH 596
             P  S+GQ     GT PA   P  S  L  S        L  ++P  E     A  ++ H
Sbjct: 876  -PQASQGQAP--LGTSPAAAYPHTSLQLPASQSA-----LQSQQPPREQPLPPAPLAMPH 927

Query: 597  AKPTAAMDVPDVGNMVSD-----LPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMF 651
             KP     +P +    +      L G       A  LP  P        +  H   A   
Sbjct: 928  IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNA-NLPPPPALKPLSSLSTHHPPSA--- 983

Query: 652  RKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSP 711
                   P PL        P S P P+ PA  P         L Q        S  LP P
Sbjct: 984  ------HPPPLQLM-----PQSQPLPSSPAQPPG--------LTQ--------SQNLPPP 1016

Query: 712  PAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQHFTGLH 771
            PA     P      +P P  AQ P     P P   P         + PG S +   +G  
Sbjct: 1017 PASH--PPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAA 1074

Query: 772  ASLCDAISGSVAHSPPEKLRE 792
            AS      GS    P  +++E
Sbjct: 1075 ASGGSIAGGSSCPLPTVQIKE 1095



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 86/324 (26%), Positives = 114/324 (35%), Gaps = 61/324 (18%)

Query: 67   TPYPPLYS-TGMAGPPLQADNLLTNCLFYRSPAEGPEKMQDSSPVELLPFSPQAHSYPGP 125
            +P+PPL   TG AG P  A +     L  + P  GP  +Q + P+   P  PQ    P  
Sbjct: 821  SPHPPLQPLTGSAGQP-SAPSHAQPPLHGQGPP-GPHSLQ-AGPLLQHPGPPQPFGLPPQ 877

Query: 126  PLAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWTLATGPLLPSADPPCSLAPAPSKGQT 185
                  P+  +P      T L   A +  L         PL P+      + P P+    
Sbjct: 878  ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT---- 933

Query: 186  LDGTFLRGVPA----------EGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYP 235
               T +  +PA           G S  S  +  P  P L+   ++ ST    S +  P P
Sbjct: 934  ---TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL-STHHPPSAH--PPP 987

Query: 236  RNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQ 295
                      PSSP    AQP G       P   PP  HPP    Q  P PP  +HP   
Sbjct: 988  LQLMPQSQPLPSSP----AQPPGLTQSQNLPP--PPASHPPTGLHQVAPQPPFAQHPFVP 1041

Query: 296  GSYSPALP----------------LQP--LGGHKGTGYQAGGLGSP----YLRQQA---A 330
            G   P  P                 QP   G     G  AGG   P     ++++A   A
Sbjct: 1042 GGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDA 1101

Query: 331  QAPYIPPLGLDAYPYPSAPLPAPS 354
            + P  PP      P P +P P P+
Sbjct: 1102 EEPESPP------PPPRSPSPEPT 1119



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 64/252 (25%), Positives = 88/252 (34%), Gaps = 52/252 (20%)

Query: 514 DYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVA 573
           D  D+     +T P   + + + + + S  Q +  +   PA + P+G  P   S      
Sbjct: 700 DPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP 759

Query: 574 LDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPV 633
             L    PT  A+ V    S     PTA                     ++AP  P  P 
Sbjct: 760 -QLPTPGPTPSATAVPPQGS-----PTA---------------------SQAPNQPQAP- 791

Query: 634 TTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTP-------TSAPAPTQPAPTPTS 686
            T  +P T+   + A   ++     P P P+   P  P        SAP+  QP P    
Sbjct: 792 -TAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQP-PLHGQ 849

Query: 687 GPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAPAPA 746
           GP G   L   PL      L  P PP      P   P   P  ++ QAP     PA A  
Sbjct: 850 GPPGPHSLQAGPL------LQHPGPP-----QPFGLP---PQASQGQAPLGT-SPAAAYP 894

Query: 747 PVAGPAPASTSA 758
             +   PAS SA
Sbjct: 895 HTSLQLPASQSA 906


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 116/445 (26%), Positives = 159/445 (35%), Gaps = 104/445 (23%)

Query: 168  PSADPPCSLAPAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLA 227
            PS+ PP      P+ G T   T    VP +GS   S     P  P               
Sbjct: 751  PSSAPP-GTPQLPTPGPTPSAT---AVPPQGSPTASQAPNQPQAP--------------- 791

Query: 228  SRYTGPYPRNS-KQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPP------ 280
               T P P    +QA +  P  P                P+ +PPPH P PHPP      
Sbjct: 792  ---TAPVPHTHIQQAPALHPQRP----------------PSPHPPPH-PSPHPPLQPLTG 831

Query: 281  -QALPCPPACRHPEKQGSYSP---ALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQAPYIP 336
                P  P+   P   G   P   +L   PL  H G     G      L  QA+Q     
Sbjct: 832  SAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFG------LPPQASQGQ--A 883

Query: 337  PLGLD---AYPYPSAPLPAPSPGLKLEPPLTPR-CPLDFAPQTLSFPYARDDLSLYGASP 392
            PLG     AYP+ S  LPA    L+ + P  PR  PL  AP  L+ P+ +          
Sbjct: 884  PLGTSPAAAYPHTSLQLPASQSALQSQQP--PREQPLPPAP--LAMPHIK---------- 929

Query: 393  GLGGTPPSQNNVRAVPQPGAFQ---RACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEK 449
                 PP    +  +P P A +       P P S   + P  PA +       P      
Sbjct: 930  -----PPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALK-------PLSSLST 977

Query: 450  LQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSL 509
              P  +      ++ +  P+P + PA PP   + Q+LP      PP+S P   +  V   
Sbjct: 978  HHPPSAHPPPLQLMPQSQPLP-SSPAQPPGLTQSQNLPP-----PPASHPPTGLHQVAPQ 1031

Query: 510  APYRDYLDVPA--PEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSG--SKPLR 565
             P+  +  VP   P  T     +T+ P + P TS      C G   +    +G  S PL 
Sbjct: 1032 PPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTS--AQPPCSGAAASGGSIAGGSSCPLP 1089

Query: 566  GSLKEEVALDLSVRKPTAEASPVKA 590
                +E ALD    +P +   P ++
Sbjct: 1090 TVQIKEEALD-DAEEPESPPPPPRS 1113



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 137/548 (25%), Positives = 178/548 (32%), Gaps = 141/548 (25%)

Query: 228  SRYTGPYPRNSKQAMSEGPSSPWTQLAQPLGPPCQ-DTGPTHYPPPHHPPPHPPQAL--- 283
            +R T P   + +   S+  SS   Q+ Q   P  Q  TG T  P P   PP  PQ     
Sbjct: 708  NRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVT--PAPSSAPPGTPQLPTPG 765

Query: 284  PCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQA--PYIPPLGLD 341
            P P A   P +    +   P QP         QA     P+   Q A A  P  PP    
Sbjct: 766  PTPSATAVPPQGSPTASQAPNQP---------QAPTAPVPHTHIQQAPALHPQRPPS--- 813

Query: 342  AYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQ 401
              P+P  P P+P P L+   PLT       AP              +   P  G  PP  
Sbjct: 814  --PHPP-PHPSPHPPLQ---PLTGSAGQPSAPS-------------HAQPPLHGQGPPGP 854

Query: 402  NNVRAVP---QPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHS 458
            ++++A P    PG  Q    P  ASQ  +        A   T   S +    Q  L    
Sbjct: 855  HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT---SLQLPASQSALQSQQ 911

Query: 459  GPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDV 518
             P    R+ P+P  P A+P               +PP + P+P                +
Sbjct: 912  PP----REQPLPPAPLAMP-------------HIKPPPTTPIP---------------QL 939

Query: 519  PAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSV 578
            PAP+A   P          P  S          LP    P   KPL           LS 
Sbjct: 940  PAPQAHKHP----------PHLSGPSPFSMNANLPP---PPALKPLSS---------LST 977

Query: 579  RKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAM 638
              P +   P           P++    P +              T++  LP  P +    
Sbjct: 978  HHPPSAHPPPLQLMPQSQPLPSSPAQPPGL--------------TQSQNLPPPPASH--- 1020

Query: 639  PRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPA-PTPTSGPIGLRILAQQ 697
            P T  H            + P P P A  P  P   P  T P  P+ ++ P G    AQ 
Sbjct: 1021 PPTGLHQ-----------VAPQP-PFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 1068

Query: 698  PLSVTCFSLALPSPPAVAVASPAPAP-------APSPAPARAQAPASARDPAPAPAPVAG 750
            P S      A  S  ++A  S  P P       A   A      P   R P+P P  V  
Sbjct: 1069 PCSG-----AAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDT 1123

Query: 751  PAPASTSA 758
            P+ AS SA
Sbjct: 1124 PSHASQSA 1131



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 100/441 (22%), Positives = 128/441 (29%), Gaps = 84/441 (19%)

Query: 357  LKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRA 416
            L+ +PP   + P    P   S P     L   G +P     PP Q +  A   P   Q  
Sbjct: 734  LQAQPPAL-QAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPP-QGSPTASQAPNQPQAP 791

Query: 417  CQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPAL 476
              P+P +     P                    L P+      PP      P P   P L
Sbjct: 792  TAPVPHTHIQQAPA-------------------LHPQRPPSPHPP------PHPSPHPPL 826

Query: 477  PPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDS 536
             P             A+PP     P   +     P   +   P P               
Sbjct: 827  QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP----------- 875

Query: 537  APATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEH 596
             P  S+GQ     GT PA   P  S  L  S        L  ++P  E     A  ++ H
Sbjct: 876  -PQASQGQAP--LGTSPAAAYPHTSLQLPASQSA-----LQSQQPPREQPLPPAPLAMPH 927

Query: 597  AKPTAAMDVPDVGNMVSD-----LPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMF 651
             KP     +P +    +      L G       A  LP  P        +  H   A   
Sbjct: 928  IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNA-NLPPPPALKPLSSLSTHHPPSA--- 983

Query: 652  RKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSP 711
                   P PL        P S P P+ PA  P         L Q        S  LP P
Sbjct: 984  ------HPPPLQLM-----PQSQPLPSSPAQPPG--------LTQ--------SQNLPPP 1016

Query: 712  PAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQHFTGLH 771
            PA     P      +P P  AQ P     P P   P         + PG S +   +G  
Sbjct: 1017 PASH--PPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAA 1074

Query: 772  ASLCDAISGSVAHSPPEKLRE 792
            AS      GS    P  +++E
Sbjct: 1075 ASGGSIAGGSSCPLPTVQIKE 1095



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 86/324 (26%), Positives = 114/324 (35%), Gaps = 61/324 (18%)

Query: 67   TPYPPLYS-TGMAGPPLQADNLLTNCLFYRSPAEGPEKMQDSSPVELLPFSPQAHSYPGP 125
            +P+PPL   TG AG P  A +     L  + P  GP  +Q + P+   P  PQ    P  
Sbjct: 821  SPHPPLQPLTGSAGQP-SAPSHAQPPLHGQGPP-GPHSLQ-AGPLLQHPGPPQPFGLPPQ 877

Query: 126  PLAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWTLATGPLLPSADPPCSLAPAPSKGQT 185
                  P+  +P      T L   A +  L         PL P+      + P P+    
Sbjct: 878  ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT---- 933

Query: 186  LDGTFLRGVPA----------EGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYP 235
               T +  +PA           G S  S  +  P  P L+   ++ ST    S +  P P
Sbjct: 934  ---TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL-STHHPPSAH--PPP 987

Query: 236  RNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQ 295
                      PSSP    AQP G       P   PP  HPP    Q  P PP  +HP   
Sbjct: 988  LQLMPQSQPLPSSP----AQPPGLTQSQNLPP--PPASHPPTGLHQVAPQPPFAQHPFVP 1041

Query: 296  GSYSPALP----------------LQP--LGGHKGTGYQAGGLGSP----YLRQQA---A 330
            G   P  P                 QP   G     G  AGG   P     ++++A   A
Sbjct: 1042 GGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDA 1101

Query: 331  QAPYIPPLGLDAYPYPSAPLPAPS 354
            + P  PP      P P +P P P+
Sbjct: 1102 EEPESPP------PPPRSPSPEPT 1119



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 64/252 (25%), Positives = 88/252 (34%), Gaps = 52/252 (20%)

Query: 514 DYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVA 573
           D  D+     +T P   + + + + + S  Q +  +   PA + P+G  P   S      
Sbjct: 700 DPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP 759

Query: 574 LDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPV 633
             L    PT  A+ V    S     PTA                     ++AP  P  P 
Sbjct: 760 -QLPTPGPTPSATAVPPQGS-----PTA---------------------SQAPNQPQAP- 791

Query: 634 TTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTP-------TSAPAPTQPAPTPTS 686
            T  +P T+   + A   ++     P P P+   P  P        SAP+  QP P    
Sbjct: 792 -TAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQP-PLHGQ 849

Query: 687 GPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAPAPA 746
           GP G   L   PL      L  P PP      P   P   P  ++ QAP     PA A  
Sbjct: 850 GPPGPHSLQAGPL------LQHPGPP-----QPFGLP---PQASQGQAPLGT-SPAAAYP 894

Query: 747 PVAGPAPASTSA 758
             +   PAS SA
Sbjct: 895 HTSLQLPASQSA 906


>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
          Length = 1350

 Score = 67.0 bits (162), Expect = 9e-11
 Identities = 103/370 (27%), Positives = 134/370 (36%), Gaps = 69/370 (18%)

Query: 143  STCLGEGA-VKRPLDV-----DWTLATGPLLPSADPPCSLAPAPSKGQTLDGTFLRGVPA 196
            ST LGE A V    D+     D++     LLP       L P+ S G             
Sbjct: 1035 STLLGEDAEVAADFDMEGDVDDYSAEVEELLPQ-----HLQPSSSSGL------------ 1077

Query: 197  EGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYPRNSKQAMSEGPSSPWTQLAQP 256
             G+S  SS   SPCQ        + S     SR     P       S   + P T L Q 
Sbjct: 1078 -GTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQK 1136

Query: 257  LGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQ 316
               P Q   P   PPP    P  P   P PP  R P   G+ SPA   +  GG       
Sbjct: 1137 --DPAQPLEPKRPPPPR---PVAPPTRPAPPQ-RPPPPSGARSPAPTRKEFGG------- 1183

Query: 317  AGGLGSPYLRQQAAQAPYIPPLGLD-----AYPYPSAPLPAPSPG--LKLEPPLTPRCPL 369
             G   SP + ++  +AP  P          + P P A L  P P       P + PR  +
Sbjct: 1184 IGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGV 1243

Query: 370  DFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEP 429
              APQ+    +AR       AS G   TP SQ+      +   F      LP      EP
Sbjct: 1244 ISAPQS----HAR-------ASAGRL-TPESQSKTSETSKGSTF------LP------EP 1279

Query: 430  VRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQK 489
            ++P      ++ LP    ++LQ  L   + P       P   TPP  PP +R   SLP +
Sbjct: 1280 LKPQAAFPPQSSLPP-PAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSE 1338

Query: 490  EDARPPSSPP 499
              ++P    P
Sbjct: 1339 ASSQPQQEQP 1348



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 51/201 (25%), Positives = 84/201 (41%), Gaps = 20/201 (9%)

Query: 567  SLKEEVALD-LSVRKPTAEASPVKASRSVEHAKPTAAMDVP-DVGNMVSDLPGLKKIDTE 624
            +L+EE++L+ +S+  P++ +S +      E A+  A  D+  DV +  +++  L     +
Sbjct: 1015 NLEEEMSLEKISIALPSSTSSTLLG----EDAEVAADFDMEGDVDDYSAEVEELLPQHLQ 1070

Query: 625  APGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTP 684
                 G+  +  + PRT+   S          +   P+P+  +P  P+ AP+ T   P+ 
Sbjct: 1071 PSSSSGLGTSPSSSPRTSPCQSPT--------ISEGPVPS--LPIRPSRAPSRTPGPPSA 1120

Query: 685  TSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAPA 744
             S PI  +     P       L    PP     +P   PAP   P R   P+ AR PAP 
Sbjct: 1121 QSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAP---PQRPPPPSGARSPAPT 1177

Query: 745  PAPVAG-PAPASTSAPGDSLE 764
                 G  AP S       +E
Sbjct: 1178 RKEFGGIGAPPSPGVARREME 1198



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 77/293 (26%), Positives = 96/293 (32%), Gaps = 53/293 (18%)

Query: 472  TPPALPPCARECQSLPQKEDARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSAT 531
            T P+  P    CQS P   +   PS P          + P R      AP  T  P SA 
Sbjct: 1079 TSPSSSPRTSPCQS-PTISEGPVPSLP----------IRPSR------APSRTPGPPSAQ 1121

Query: 532  AEP-DSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKA 590
            + P D+ PAT           LP ++     +P R      VA       P     P  A
Sbjct: 1122 SSPIDAQPATP----------LPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGA 1171

Query: 591  SRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFM 650
                   K    +  P         PG+ + + EAP  PG     D + R+         
Sbjct: 1172 RSPAPTRKEFGGIGAPPS-------PGVARREMEAPKSPGT-TRKDNIGRSQPSPQAGLA 1223

Query: 651  F---RKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCF-SL 706
                  +   RP   P A V S P S    +    TP S         Q   S T   S 
Sbjct: 1224 GPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPES---------QSKTSETSKGST 1274

Query: 707  ALPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAP 759
             LP P     A P  +  P PA  R Q P     P  AP P +GP P   + P
Sbjct: 1275 FLPEPLKPQAAFPPQSSLPPPAQ-RLQEPLV---PVAAPMPQSGPQPNLETPP 1323



 Score = 34.7 bits (78), Expect = 0.48
 Identities = 41/180 (22%), Positives = 63/180 (35%), Gaps = 22/180 (12%)

Query: 390  ASPGLGGTPPSQNNVRAVPQPGAFQRACQPLP---ASQPCSEPVRPAQE-----AEEKTW 441
            +S GLG +P S         P   +     LP   +  P   P  P+ +     A+  T 
Sbjct: 1073 SSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATP 1132

Query: 442  LPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMP 501
            LP  +K+  QP   +   PP  +     P  P   PP +      P +++     +PP P
Sbjct: 1133 LP--QKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSP 1190

Query: 502  VIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKG----CRGTLPAQEG 557
             +         R  ++ P    TT  D+      S  A   G         R T+P + G
Sbjct: 1191 GV--------ARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAG 1242


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 134/574 (23%), Positives = 188/574 (32%), Gaps = 111/574 (19%)

Query: 233 PYPRNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYP--PPHHPPPHPPQALPCPPACR 290
           P P       S G S      A P  PP    G  + P  PP    PH    LP PPA R
Sbjct: 254 PPPTTPISVSSSGASG-----APPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALR 308

Query: 291 HPEKQGSYSPALPLQPLGGHKGTGYQAG-GLGS----PYLRQQAAQAPY-IPPLGLDA-- 342
                 +  P L  QPL GH  + +  G G+G     P      A +P+ +PP    A  
Sbjct: 309 PLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA 368

Query: 343 ----YPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYA---RDDLSLYGASPGLG 395
               +PY S+   + +         +   P   +    S+P++      LS+    P   
Sbjct: 369 PPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYT 428

Query: 396 ------------GTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEP-VRPAQEAEEKTWL 442
                       G PP     R +    A      P   +Q  + P V       ++   
Sbjct: 429 QPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQ 488

Query: 443 PSCRKEKLQPRLSEH---SGPPIVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPP 499
              ++++ Q +  +H   SGPP           PP   P   E  S      A P +  P
Sbjct: 489 QQQQQQQQQQQQQQHHGNSGPP-----------PPGAFPHPLEGGS---SHHAHPYAMSP 534

Query: 500 MPVIDNVFSLAPYRDYLDVPA--PEATTEPDSATAEPDSAPATSEGQDKGC--RGTLPAQ 555
                   SL   R Y   PA  P   ++   + A P+  P +S         +G+ P  
Sbjct: 535 --------SLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCS 586

Query: 556 EGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDL 615
             PS S+  +G+      +          ++ +    S      TA+   P      +  
Sbjct: 587 H-PSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPS 645

Query: 616 PGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAP 675
           PG  K  T     PG P         +F +     +R      P   P    P +PT  P
Sbjct: 646 PGAYKTATPPGYKPGSP--------PSFRTGTPPGYRGTS---PPAGPGTFKPGSPTVGP 694

Query: 676 APTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAP 735
            P  PA     GP GL               +LP PPA   + P     P  A    Q P
Sbjct: 695 GPLPPA-----GPSGLP--------------SLPPPPAAPASGP-----PLSATQIKQEP 730

Query: 736 AS-----------ARDPAPAPAPVAGPAPASTSA 758
           A            AR P+P P  V  P+ AS SA
Sbjct: 731 AEEYETPESPVPPARSPSPPPKVVDVPSHASQSA 764



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 148/681 (21%), Positives = 215/681 (31%), Gaps = 174/681 (25%)

Query: 178 PAPSKGQTLDGTFLRGVPAEGSSK-----DSSGSFSPCQPFLEKYQTIHSTGFLASRYTG 232
           P P     LD    R +  +GSS        + S SP         +I+S G + +    
Sbjct: 97  PRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSP---------SIYSPGSVEN---- 143

Query: 233 PYPRNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACR-- 290
               +S   +S+GP+ P+                 H PP   P P PP + P  P     
Sbjct: 144 --DSDSSSGLSQGPARPY-----------------HPPPLFPPSPQPPDSTPRQPEASFE 184

Query: 291 -HPE--KQGSYSP--------------ALPLQPLGGHKGTGYQAGGLGSPYL--RQQAAQ 331
            HP     G ++P              A P  P     GTG   G L  P +  +   A 
Sbjct: 185 PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTG---GVLSGPPMGPKGGGAA 241

Query: 332 APYIPPLGLDAYPYPSAPLPAPSPGLKLEPPLTPRCP------LDFAPQTLSFPYARDDL 385
           +    P G   +P P+ P+   S G    PP  P         L  AP   +FP+   +L
Sbjct: 242 SSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNL 301

Query: 386 -----------------------------SLYGASPGLGGTPPS-QNNVRAVPQPGAFQR 415
                                        S +    G+GG PP  +      P P +   
Sbjct: 302 PPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPP 361

Query: 416 ACQPLPA---------SQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPP---IV 463
           A    PA         S   S     +  +   +  P    + L      HS PP   + 
Sbjct: 362 ASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPS--YPHSFPPPTSLS 419

Query: 464 IRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPM-PVIDNVFSLAPYRDYLDVPAPE 522
           + + P   T P+LP  A   Q         PP  PP   ++ N  S A    +      +
Sbjct: 420 VSNQPPKYTQPSLPSQAVWSQG--------PPPPPPYGRLLAN--SNAHPGPFPPSTGAQ 469

Query: 523 ATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQ-EGPSGSKPLRGSLKEEVALDLSVRKP 581
           +T  P  +T          + Q +  +     Q  G SG  P                 P
Sbjct: 470 STAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP-----------------P 512

Query: 582 TAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPG-------LKKIDTEAPGLPGVPVT 634
            A   P++   S  HA P A    P +G++    PG         ++     G  G PV+
Sbjct: 513 GAFPHPLEGGSS-HHAHPYAMS--PSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVS 569

Query: 635 TDAMPRTNFHSSVAFMFRKFKILRP--------APLPAAVVPSTPTSAPAPTQPAPTPTS 686
           + +      +SS +     +    P        AP P   VP+  TS+   +    T  S
Sbjct: 570 SSS------NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVAS 623

Query: 687 GPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAPAP- 745
            P G +     P     +    PSP A   A+P      SP   R   P   R  +P   
Sbjct: 624 SPAGYK--TASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAG 681

Query: 746 -------APVAGPAPASTSAP 759
                  +P  GP P   + P
Sbjct: 682 PGTFKPGSPTVGPGPLPPAGP 702



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 140/611 (22%), Positives = 199/611 (32%), Gaps = 127/611 (20%)

Query: 235 PRNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEK 294
           PR  + +    PS   T    P+ PP   T      PP  PPPHP           +P  
Sbjct: 176 PRQPEASFEPHPSVTPTGYHAPMEPP---TSRMFQAPPGAPPPHPQL---------YPGG 223

Query: 295 QGSYSPALPLQPLGGHKGT--GYQAGGLGSPY----LRQQAAQAPYIPPLGLDAYPY--- 345
            G      P+ P GG   +  G   GG   P     +   ++ A   PP      P    
Sbjct: 224 TGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGG 283

Query: 346 --PSAPLPAP----SPGLKLEPPLTPRCPLDFAPQTLSFPYARDDL-SLYGASPGLGGTP 398
             PSAP PA     +P L   P L P      +P  L        L S +    G+GG P
Sbjct: 284 NLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLP 343

Query: 399 PS-QNNVRAVPQPGAFQRACQPLPA---------SQPCSEPVRPAQEAEEKTWLPSCRKE 448
           P  +      P P +   A    PA         S   S     +  +   +  P    +
Sbjct: 344 PGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQ 403

Query: 449 KLQPRLSEHSGPP---IVIRDSPVPCTPPALPPCARECQSLPQKEDARPPSSPPMP-VID 504
            L      HS PP   + + + P   T P+LP  A   Q         PP  PP   ++ 
Sbjct: 404 ALPSY--PHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQG--------PPPPPPYGRLLA 453

Query: 505 NVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQE-GPSGSKP 563
           N  S A    +      ++T  P  +T          + Q +  +     Q  G SG  P
Sbjct: 454 N--SNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP 511

Query: 564 LRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGL----- 618
                            P A   P++   S  HA P A    P +G++    PG      
Sbjct: 512 -----------------PGAFPHPLEGGSS-HHAHPYAMS--PSLGSLRPYPPGPAHLPP 551

Query: 619 --KKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRP--------APLPAAVVP 668
              ++     G  G PV++ +      +SS +     +    P        AP P   VP
Sbjct: 552 PHSQVSYSQAGPNGPPVSSSS------NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVP 605

Query: 669 STPTS--------APAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALP------SPPAV 714
           +  TS        A   + PA   T+ P G     ++  S   +  A P      SPP+ 
Sbjct: 606 TVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSF 665

Query: 715 AVASPA-------PA---------PAPSPAPARAQAPASARDPAPAPAPVA-GPAPASTS 757
              +P        PA         P   P P     P+      P PA  A GP  ++T 
Sbjct: 666 RTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQ 725

Query: 758 APGDSLEQHFT 768
              +  E++ T
Sbjct: 726 IKQEPAEEYET 736



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 111/473 (23%), Positives = 149/473 (31%), Gaps = 92/473 (19%)

Query: 160 TLATGPLLPSADPPCSLAPAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQT 219
           TLA  P   S  P  S APAP        +      A  SS  SS S SP          
Sbjct: 351 TLAPSP--HSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASP---------- 398

Query: 220 IHSTGFLASRYTGPYPRNSKQAMSEGPSSPWTQLAQPLGPP--CQDTGPTHYPPPHHPPP 277
                F AS+    YP +           P T L+    PP   Q + P+       PPP
Sbjct: 399 -----FPASQALPSYPHS---------FPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPP 444

Query: 278 HPPQALPCPPACRH----PEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQAP 333
            PP       +  H    P   G+ S A P  P+  H     Q         +QQ  Q  
Sbjct: 445 PPPYGRLLANSNAHPGPFPPSTGAQSTAHP--PVSTHHHHHQQQQQQQQQQQQQQQQQQQ 502

Query: 334 YIPPLGLDAYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPG 393
           +    G    P P    P                PL+      + PYA         SP 
Sbjct: 503 HHGNSG----PPPPGAFPH---------------PLEGGSSHHAHPYA--------MSPS 535

Query: 394 LGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPR 453
           LG   P       +P P +     Q  P   P S     +    + ++  S       P+
Sbjct: 536 LGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQ 595

Query: 454 LSEHSGPPI---------------VIRDSPV---PCTPPALPPCARECQSLPQKEDARPP 495
            + +  PP+                +  SP      +PP  PP  +   S    + A PP
Sbjct: 596 GAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPP 655

Query: 496 S-SPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPA 554
              P  P      +   YR     PA   T +P S T  P   P        G     P 
Sbjct: 656 GYKPGSPPSFRTGTPPGYRG-TSPPAGPGTFKPGSPTVGPGPLPPAG---PSGLPSLPPP 711

Query: 555 QEGPSGSKPLRGS-LKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVP 606
              P+   PL  + +K+E A +    +     SPV  +RS   + P   +DVP
Sbjct: 712 PAAPASGPPLSATQIKQEPAEEYETPE-----SPVPPARS--PSPPPKVVDVP 757



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 45/165 (27%), Positives = 66/165 (40%), Gaps = 28/165 (16%)

Query: 657 LRPAPLPAAVVPSTPTSAPAPT-QPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVA 715
           L  AP PA     TP   P P  +P    ++ P GL     QPL        LPSP A+ 
Sbjct: 285 LPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGL---GAQPLPGH-----LPSPHAMG 336

Query: 716 --------------VASPAP---APAPSPAPA-RAQAPASARDPAPAPAPVAGPAPASTS 757
                           +P+P    PA S APA   + P S+   + A A  +  + +S++
Sbjct: 337 QGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSA 396

Query: 758 APGDSLEQHFTGLHASLCDAISGSVAHSPPEKLREWLETAGPWGQ 802
           +P  +  Q       S     S SV++ PP+  +  L +   W Q
Sbjct: 397 SPFPA-SQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQ 440



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 34/111 (30%), Positives = 47/111 (42%), Gaps = 6/111 (5%)

Query: 940  PTVARDEPESLALAQKS-PAPKVRKPGRKPPTPGPEKAEAAAGEESCGASPTPATSASPP 998
            PT+A   P SL  A  S PAP +R P     +     A +++   S  ASP PA+ A P 
Sbjct: 350  PTLA-PSPHSLPPASSSAPAPPMRFP-YSSSSSSSAAASSSSSSSSSSASPFPASQALPS 407

Query: 999  GPTLKARFRSLL---ETAWLNGLALPTWGHKSSRPDQPSPCPQLLDSQSHH 1046
             P       SL    +       +LP+    S  P  P P  +LL + + H
Sbjct: 408  YPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAH 458


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.133    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,942,600
Number of Sequences: 37866
Number of extensions: 4180764
Number of successful extensions: 59805
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 591
Number of HSP's successfully gapped in prelim test: 1747
Number of HSP's that attempted gapping in prelim test: 23675
Number of HSP's gapped (non-prelim): 21556
length of query: 1047
length of database: 18,247,518
effective HSP length: 113
effective length of query: 934
effective length of database: 13,968,660
effective search space: 13046728440
effective search space used: 13046728440
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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