Guide to the Human Genome
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Search of human proteins with 4507961

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507961 zinc finger protein 36, C3H type, homolog [Homo
sapiens]
         (326 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507961 zinc finger protein 36, C3H type, homolog [Homo sapiens]   684   0.0  
gi|15812180 butyrate response factor 1 [Homo sapiens]                 155   4e-38
gi|15812178 zinc finger protein 36, C3H type-like 2 [Homo sapiens]    146   2e-35
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  59   6e-09
gi|163965366 nascent polypeptide-associated complex alpha subuni...    55   6e-08
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             53   3e-07
gi|155722994 zinc finger CCCH-type containing 3 [Homo sapiens]         52   9e-07
gi|122937239 zinc finger CCCH-type domain containing 5 [Homo sap...    52   9e-07
gi|146134388 YLP motif containing 1 [Homo sapiens]                     49   6e-06
gi|31652264 RNA binding motif protein 26 [Homo sapiens]                47   2e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    47   3e-05
gi|32880199 makorin ring finger protein 2 [Homo sapiens]               46   4e-05
gi|239788462 dihydrouridine synthase 3-like isoform 1 [Homo sapi...    46   5e-05
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho...    46   5e-05
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho...    46   5e-05
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho...    46   5e-05
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom...    46   5e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    45   1e-04
gi|116256464 hypothetical protein LOC343990 [Homo sapiens]             45   1e-04
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p...    44   1e-04
gi|40548415 dishevelled associated activator of morphogenesis 2 ...    44   1e-04
gi|118766347 zinc finger CCCH-type domain containing 6 [Homo sap...    44   1e-04
gi|194272180 plexin B1 [Homo sapiens]                                  44   2e-04
gi|40254442 plexin B1 [Homo sapiens]                                   44   2e-04
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  44   3e-04
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                44   3e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    44   3e-04
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                44   3e-04
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                44   3e-04
gi|73695473 roquin [Homo sapiens]                                      44   3e-04

>gi|4507961 zinc finger protein 36, C3H type, homolog [Homo sapiens]
          Length = 326

 Score =  684 bits (1766), Expect = 0.0
 Identities = 326/326 (100%), Positives = 326/326 (100%)

Query: 1   MDLTAIYESLLSLSPDVPVPSDHGGTESSPGWGSSGPWSLSPSDSSPSGVTSRLPGRSTS 60
           MDLTAIYESLLSLSPDVPVPSDHGGTESSPGWGSSGPWSLSPSDSSPSGVTSRLPGRSTS
Sbjct: 1   MDLTAIYESLLSLSPDVPVPSDHGGTESSPGWGSSGPWSLSPSDSSPSGVTSRLPGRSTS 60

Query: 61  LVEGRSCGWVPPPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFSESGRCRY 120
           LVEGRSCGWVPPPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFSESGRCRY
Sbjct: 61  LVEGRSCGWVPPPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFSESGRCRY 120

Query: 121 GAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPV 180
           GAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPV
Sbjct: 121 GAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPV 180

Query: 181 LRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPL 240
           LRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPL
Sbjct: 181 LRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPL 240

Query: 241 ARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGSDSPVFE 300
           ARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGSDSPVFE
Sbjct: 241 ARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGSDSPVFE 300

Query: 301 AGVFAPPQPVAAPRRLPIFNRISVSE 326
           AGVFAPPQPVAAPRRLPIFNRISVSE
Sbjct: 301 AGVFAPPQPVAAPRRLPIFNRISVSE 326


>gi|15812180 butyrate response factor 1 [Homo sapiens]
          Length = 338

 Score =  155 bits (393), Expect = 4e-38
 Identities = 104/266 (39%), Positives = 125/266 (46%), Gaps = 46/266 (17%)

Query: 84  GPELSPSPTSPTATSTTPSRYKTELCRTFSESGRCRYGAKCQFAHGLGELRQANRHPKYK 143
           G  L P+   P       SRYKTELCR F E+G C+YG KCQFAHG+ ELR   RHPKYK
Sbjct: 95  GERLLPTQKQPGGGQVNSSRYKTELCRPFEENGACKYGDKCQFAHGIHELRSLTRHPKYK 154

Query: 144 TELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPG------HPPVLRQSISFSGLPSGRRTS 197
           TELC  F+  G CPYG RCHFIHN  E  A  G        P L+ S SF+G PS   T+
Sbjct: 155 TELCRTFHTIGFCPYGPRCHFIHNAEERRALAGARDLSADRPRLQHSFSFAGFPSAAATA 214

Query: 198 PPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPLARRDPTPVCCPSCRRAT 257
                    + +    SP+S  PPP    LS      +P  P    +P            
Sbjct: 215 ---------AATGLLDSPTSITPPP---ILSADDLLGSPTLPDGTNNPFAFSSQELASLF 262

Query: 258 PISVWGPLGGLVRT----------------PSVQSLGSDPDEY-ASSGSSLGGSDSPVFE 300
             S+  P GG   T                PS Q   SD + Y +SS SS  GSDSP  +
Sbjct: 263 APSMGLPGGGSPTTFLFRPMSESPHMFDSPPSPQDSLSDQEGYLSSSSSSHSGSDSPTLD 322

Query: 301 AGVFAPPQPVAAPRRLPIFNRISVSE 326
                        RRLPIF+R+S+S+
Sbjct: 323 NS-----------RRLPIFSRLSISD 337


>gi|15812178 zinc finger protein 36, C3H type-like 2 [Homo sapiens]
          Length = 494

 Score =  146 bits (369), Expect = 2e-35
 Identities = 83/175 (47%), Positives = 91/175 (52%), Gaps = 28/175 (16%)

Query: 102 SRYKTELCRTFSESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSR 161
           +RYKTELCR F ESG C+YG KCQFAHG  ELR   RHPKYKTELC  F+  G CPYG R
Sbjct: 152 TRYKTELCRPFEESGTCKYGEKCQFAHGFHELRSLTRHPKYKTELCRTFHTIGFCPYGPR 211

Query: 162 CHFIHNPSEDLAAP-------------------GHP----PVLRQSISFSGLPSGRRTSP 198
           CHFIHN  E   AP                   G P    P L  S+SFSG PSG     
Sbjct: 212 CHFIHNADERRPAPSGGASGDLRAFGTRDALHLGFPREPRPKLHHSLSFSGFPSGHH--Q 269

Query: 199 PPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPLARRDPTPVCCPSC 253
           PP GL  P L     SP+S  PPP     + S  S+A     A    TP   P+C
Sbjct: 270 PPGGLESPLLLD---SPTSRTPPPPSCSSASSCSSSASSCSSASAASTPSGAPTC 321



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 37/116 (31%), Positives = 51/116 (43%), Gaps = 29/116 (25%)

Query: 214 SPSSSPPPPGDLPLSPSAFSAAPGTPLARRDPTPVCCPSCRRATPISVWGPLGGLVRTPS 273
           +P + PP P    L P+  +A P  P + + P        RR +   V+         PS
Sbjct: 404 APPAQPPAPPSATL-PAGAAAPPSPPFSFQLP--------RRLSDSPVFDA------PPS 448

Query: 274 VQSLGSDPDEYAS---SGSSLGGSDSPVFEAGVFAPPQPVAAPRRLPIFNRISVSE 326
                SD D Y S   S  SL GS+SP  + G           RRLPIF+R+S+S+
Sbjct: 449 PPDSLSDRDSYLSGSLSSGSLSGSESPSLDPG-----------RRLPIFSRLSISD 493


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 71/299 (23%), Positives = 113/299 (37%), Gaps = 27/299 (9%)

Query: 20   PSDHGGTESSPGWGSSGPWSLSPSDS---SPSGVTSRLPGRSTSLVEGR----SCGWVPP 72
            P     T S+ G     P     +D+   SPS  +S  P    +   G     S G    
Sbjct: 992  PGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQT 1051

Query: 73   PPGFA-PLAPRLGPELSPSPTSPTATSTTPSRYKTE--LCRTFSESGRCRYGAKCQFAHG 129
            PPG A P  P++  ++ P  T      ++ S+Y +   +  + S+S      +    A  
Sbjct: 1052 PPGVATPPIPKITIQI-PKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSAST 1110

Query: 130  LGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPVLRQSISFSG 189
             G+++ +       ++L    Y        S+     N S+    PG  P+ +  +S   
Sbjct: 1111 SGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSK---NSSQSGGKPGSSPITKHGLSSGS 1167

Query: 190  LPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPLARRDPTPVC 249
              +  +    P  L  PSLS  + SPS S PP G   L+ S     PGTP + +  +P+ 
Sbjct: 1168 SSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLA-SPMKPVPGTPPSSKAKSPIS 1226

Query: 250  ----------CPSCRRATPISVWGPLGGLVR--TPSVQSLGSDPDEYASSGSSLGGSDS 296
                        S       S  G  G L +   PS  S  +    ++SSGSS+  S +
Sbjct: 1227 SGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQN 1285


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 92/334 (27%), Positives = 121/334 (36%), Gaps = 63/334 (18%)

Query: 15   PDVPVPSDHGGTES-SPGWGSSGPWSLSPSDS------SPSGVTSRLPGRSTSLVEGR-- 65
            P    PS  GG  + SP W  + P +  PS        SP G  +       S   G   
Sbjct: 943  PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPAT 1002

Query: 66   -SCGWVPPPPGFAPLAPRLGPELSPSP----TSPTATSTTP--SRYKTELCRTFSESGRC 118
             S    P PP   P +P+  P  +P P    T P AT  +P  S   T L +        
Sbjct: 1003 PSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPK-------- 1054

Query: 119  RYGAKCQFAHGLGELRQANRHPKYK--------TELCHKFYLQGRCPYGSRCHFIHNPSE 170
              GA    A  L   +     P  K        T    K       P G+       P  
Sbjct: 1055 --GAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGA-------PMP 1105

Query: 171  DLAAPGHPPVLRQSISFSGLPSGRRTSPPPP--GLAGPSLSSSSFSPSSSPP-------- 220
              A P  P     +    G P+    +PP P  GLA P    +  +P+++PP        
Sbjct: 1106 PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1165

Query: 221  -PPGDLPLSPSAFSAAPGTPLARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGS 279
             PP   P +P+A   +P   LA   P+P   P+   ATP S   P GGL  TPS +   +
Sbjct: 1166 PPPKGAPTTPAATPPSPKGGLA--TPSPKGAPTTPAATPPS---PKGGLA-TPSPKGAPT 1219

Query: 280  DPDEYASSGSSLGGSDSPVFEAGVFAPPQPVAAP 313
             P   A+  S  GG  +P  +    AP  P A P
Sbjct: 1220 TP--AATPPSPKGGLATPSPKG---APTTPAATP 1248



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 89/327 (27%), Positives = 112/327 (34%), Gaps = 52/327 (15%)

Query: 15   PDVPVPSDHGG---TESSPGWGSSGPWSLS-PSDSSPSGVTSRLPGRSTSLVEGR---SC 67
            P  P P        T SSP    + P     P+  SP G  +       S   G    S 
Sbjct: 900  PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP 959

Query: 68   GWVPPPPGFAPLAPRLGPEL-SP--SPTSPTAT-------STTPSRYKTELCRTFSESGR 117
             W P PP   P +P+ GP   SP  +PT P AT         TPS          +    
Sbjct: 960  KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSP 1019

Query: 118  CRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGH 177
                A   F  G      A+  P                P G+       P+  L +P  
Sbjct: 1020 KGSPAATPFPKG------ASTPPAATPPSPKGSPAATPLPKGAPT----TPAATLPSPKG 1069

Query: 178  PPVLRQSISFSGLPSGRRTSPPPP--GLAGPSLSSSSFSPSSSPP-PPGDLPLSPSAFSA 234
             P    + S  G P+    +PP P  G A PS   +   P+++PP P G L   P     
Sbjct: 1070 GPA---TPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP--HKG 1124

Query: 235  APGTPLAR--------RDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEYAS 286
            AP TP A           P P   P+   ATP S   P GGL   P     G+     A+
Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPS---PKGGLATPP---PKGAPTTPAAT 1178

Query: 287  SGSSLGGSDSPVFEAGVFAPPQPVAAP 313
              S  GG  +P  +    AP  P A P
Sbjct: 1179 PPSPKGGLATPSPKG---APTTPAATP 1202



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 79/312 (25%), Positives = 109/312 (34%), Gaps = 49/312 (15%)

Query: 14   SPDVPVPSDHGGTESSPGWGSSGPWSLSPSDSSPSGVTSRLPGRSTSLVEGRSCGWVPPP 73
            +P   +PS  GG  +    G+  P + +P   SP G      G +T   +G      P P
Sbjct: 1059 TPAATLPSPKGGPATPSLKGAPTPPAATPP--SPKG------GPATPSPKG-----APMP 1105

Query: 74   PGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFSESGRCRYGAKCQFAHGLGEL 133
            P   P +P+ G    P   +PT  + TP   K  L     +       A      G    
Sbjct: 1106 PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG---- 1161

Query: 134  RQANRHPK------YKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPVLRQSISF 187
              A   PK        T    K  L    P G+       P+   A P  P     + S 
Sbjct: 1162 GLATPPPKGAPTTPAATPPSPKGGLATPSPKGA-------PTTPAATPPSPKGGLATPSP 1214

Query: 188  SGLPSGRRTSPPPP--GLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPLARRDP 245
             G P+    +PP P  GLA PS   +  +P+++PP P             P TP  +  P
Sbjct: 1215 KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP----------KGGPATPPPKGAP 1264

Query: 246  TPVCC--PSCR--RATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGSDSPVFEA 301
            TP     PS +   ATP     P   +V  PS +     P      G+    + +P    
Sbjct: 1265 TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPK---GGPATSPPKGAPTPPAATPPSPK 1321

Query: 302  GVFAPPQPVAAP 313
            G    P P  AP
Sbjct: 1322 GSPGTPPPKGAP 1333



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 60/250 (24%), Positives = 94/250 (37%), Gaps = 39/250 (15%)

Query: 14   SPDVPVPSDHGGTESSPGWGSSGPWSLSPSD--SSPSGVTSRLPGRSTSLVEGRSCGWVP 71
            +P +P P +   T SS    +S P +++PS    +PS     +P   TS     S    P
Sbjct: 1561 TPAIPTPKEAPATPSSKE--ASSPPAVTPSTYKGAPSPKELLIPPAVTS----PSPKEAP 1614

Query: 72   PPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFSESGRCRYGAKC-QFAHGL 130
             PP   P +P  GP       +PT+   TPS  K     T   S  C+ GA   Q + GL
Sbjct: 1615 TPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDS--PTSPASVTCKMGATVPQASKGL 1672

Query: 131  GELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPVLRQSISFSGL 190
                 A + P    E+                           AP   P++  + +  G 
Sbjct: 1673 ----PAKKGPTALKEVL-----------------------VAPAPESTPII-TAPTRKGP 1704

Query: 191  PSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPLARRDPTPVCC 250
             + + ++  PP    PS  + S  P S+  P   LP+   +   A G   +     P+  
Sbjct: 1705 QTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAP 1764

Query: 251  PSCRRATPIS 260
            P  + +TP++
Sbjct: 1765 PESKASTPLT 1774



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 81/325 (24%), Positives = 104/325 (32%), Gaps = 59/325 (18%)

Query: 13   LSPDVPVPSDHGGTESSPGWGSSGPWSLSPSDSSPSGVTSRLPGRSTSLVEGRSC----- 67
            + P    PS  GG  + P  G+  P + + +  SP G  +  P +        +      
Sbjct: 1104 MPPAATPPSPKGGLATPPHKGA--PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1161

Query: 68   GWVPPPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFSESGRCRYGAKCQFA 127
            G   PPP  AP  P   P   PSP    AT +      T      S  G    G      
Sbjct: 1162 GLATPPPKGAPTTPAATP---PSPKGGLATPSPKGAPTTPAATPPSPKG----GLATPSP 1214

Query: 128  HGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPVLRQSISF 187
             G      A       T    K  L    P G+       P      P  PP        
Sbjct: 1215 KGAPTTPAA-------TPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267

Query: 188  SGLP---SGRRTSPPPPGLAGPSL---SSSSFSPSSSPP-----PPGDLPLSPSAFSAAP 236
            +  P    G   +PP  G   P++    S    P++SPP     PP   P SP     +P
Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKG---SP 1324

Query: 237  GTPLARRDPTPVC--------CPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEYASSG 288
            GTP  +  PTP           P+    TP S  GP      TPS +     P   A++ 
Sbjct: 1325 GTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGP-----TTPSSK---EGPTPPAATP 1376

Query: 289  SSLGGSDSPVFEAGVFAPPQPVAAP 313
            S  GG            PP P   P
Sbjct: 1377 SHKGGP--------AMTPPSPKRGP 1393



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 78/302 (25%), Positives = 112/302 (37%), Gaps = 46/302 (15%)

Query: 14   SPDVPVPSDHGGTESSPGWGSSGPWSLSPSDSSPSGVTSRLPGRSTSLVEGRSCGWVPPP 73
            S D P  + H  T  SP  G+  P +++P   SP GVT  LP + T      +  +  P 
Sbjct: 846  SKDSPATT-HSPTPPSPK-GAPTPSAVTPL--SPKGVT--LPPKETPTPSVVNLPF--PK 897

Query: 74   PGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFSESGRCRYGAKCQFAHGLGEL 133
             G A  AP+  P LS + +SP     TP+     +  + S  G     A    +   G  
Sbjct: 898  EGPATPAPKQAPALSMTSSSPKKARATPA--PKGIPASPSPKGAPTPPAATPPSPKGG-- 953

Query: 134  RQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPVLRQSISFSGLPSG 193
              A   PK+                         P+   A P  P     + S  G P+ 
Sbjct: 954  -PATPSPKWA------------------------PTPPAATPPSPKGGPATPSPKGAPTP 988

Query: 194  RRTSPPPP--GLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPLARRDPTPVCCP 251
               +PP P  G A PS   +   P+ +PP P   P + + F     TP A   P+P   P
Sbjct: 989  PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP-AATPFPKGASTPPAATPPSPKGSP 1047

Query: 252  SCRRATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGSDSPVFEAGVFAPPQPVA 311
            +   ATP+    P       PS +   + P   +  G+    + +P    G  A P P  
Sbjct: 1048 A---ATPLPKGAPTTPAATLPSPKGGPATP---SLKGAPTPPAATPPSPKGGPATPSPKG 1101

Query: 312  AP 313
            AP
Sbjct: 1102 AP 1103



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 47/159 (29%), Positives = 63/159 (39%), Gaps = 24/159 (15%)

Query: 174  APGHPPVLRQSISFSGLPSGRRTSPPPPGL-AGPSLSSSSFSPSSSPPPPGDLPLSPSAF 232
            AP   P L  +   S  P   R +P P G+ A PS   +   P+++PP P   P +PS  
Sbjct: 904  APKQAPALSMT---SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP- 959

Query: 233  SAAPGTPLAR--------RDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEY 284
              AP  P A           P+P   P+   ATP S   P GG   TPS +   + P   
Sbjct: 960  KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPS---PKGG-PATPSPKGAPTPP--A 1013

Query: 285  ASSGSSLGGSDSPVFEAG-----VFAPPQPVAAPRRLPI 318
             +  S  G   +  F  G        PP P  +P   P+
Sbjct: 1014 VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 73/328 (22%), Positives = 112/328 (34%), Gaps = 66/328 (20%)

Query: 15   PDVPVPSDHGGTESSPGWGSSGPWSLSPSDSSPSGVTSRLPGRSTSLVEGRSC-----GW 69
            P    PS  G   + P  G+  P +++P   SP G T  LP  + S   G +      G 
Sbjct: 1313 PAATPPSPKGSPGTPPPKGAPTPPAVTPP--SPKG-TPTLPATTPSSKGGPTTPSSKEGP 1369

Query: 70   VPPP--------PGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFSESGRCRYG 121
             PP         P   P +P+ GP +      PT+ +  P   K       +  G     
Sbjct: 1370 TPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAA--- 1426

Query: 122  AKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPVL 181
                     G+L      P   T +  K     + P  S             AP   P  
Sbjct: 1427 -----TPSKGDLT-----PPAVTPVSLK-----KAPATS-------------APKGGPAT 1458

Query: 182  RQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDL------PLSPSAFSAA 235
              S     LP+    SP  P    P   ++S SP  +P  P  +       + PS+    
Sbjct: 1459 PSSKGDPTLPAVTPPSPKEP--PAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEV 1516

Query: 236  PGTPLARRDPTPVCCPSCRRATPISVWGPLGGLV----------RTPSVQSLGSDPDEYA 285
            P TP +RRDP         + TP ++  P   L+          +TP++ +    P   +
Sbjct: 1517 PATPSSRRDPIAPTATLLSKKTPATL-APKEALIPPAMTVPSPKKTPAIPTPKEAPATPS 1575

Query: 286  SSGSSLGGSDSPVFEAGVFAPPQPVAAP 313
            S  +S   + +P    G  +P + +  P
Sbjct: 1576 SKEASSPPAVTPSTYKGAPSPKELLIPP 1603



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 44/170 (25%), Positives = 60/170 (35%), Gaps = 24/170 (14%)

Query: 168 PSEDLAAP------GHPPVLRQSISFSGLPSGRRTSPPPP--GLAGPSLSSSSFSPSSSP 219
           P+ED  A       G    L  S S  G+    +T  PP   G AGP     + S   SP
Sbjct: 771 PTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSP 830

Query: 220 PPPGDLPLSPSAFSAAPGTPLARRDPTPVC---CPSCRRATPISVWG--------PLGGL 268
                LP +  +F  +  +P     PTP      P+    TP+S  G        P   +
Sbjct: 831 VEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSV 890

Query: 269 VRTPSVQSLGSDPDEYASSGSSLGGSDSPVFEA-----GVFAPPQPVAAP 313
           V  P  +   + P    +   S+  S      A     G+ A P P  AP
Sbjct: 891 VNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAP 940



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 82/344 (23%), Positives = 113/344 (32%), Gaps = 57/344 (16%)

Query: 14   SPDVPVPSDHGGTESSPGWGSSGPWSLSPS-DSSPSGVTSRLPGRSTSLVEGRSCGWVPP 72
            +P    PS  GG   +P     GP   SP  D +   V    P ++ +    R     P 
Sbjct: 1370 TPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPS 1429

Query: 73   -----PPGFAPL---------APRLGPELSPSPTSPTATSTT-PSRYKTELCRTFSESGR 117
                 PP   P+         AP+ GP    S   PT  + T PS  +    +  + S  
Sbjct: 1430 KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSS 1489

Query: 118  CRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGH 177
             +         G   L         +           R P       +   +    AP  
Sbjct: 1490 PKKAPATPAPMGAPTLPAVIPSSPKEVPATPS---SRRDPIAPTATLLSKKTPATLAPKE 1546

Query: 178  ---PPVLRQSISFSGLPSGRRT---SPPPPGLAGPSLSSSSFSPSSSP------PPPGDL 225
               PP +        +PS ++T     P    A PS   +S  P+ +P      P P +L
Sbjct: 1547 ALIPPAMT-------VPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL 1599

Query: 226  PLSPSAFSAAP---GTPLARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDPD 282
             + P+  S +P    TP A   P+P   P    ATP     P    V TPS  SL   P 
Sbjct: 1600 LIPPAVTSPSPKEAPTPPAVTPPSPEKGP----ATPAPKGTPTSPPV-TPS--SLKDSPT 1652

Query: 283  EYASSGSSLGGSDSPVFEAGVFAPPQPVA--------APRRLPI 318
              AS    +G +  P    G+ A   P A        AP   PI
Sbjct: 1653 SPASVTCKMGAT-VPQASKGLPAKKGPTALKEVLVAPAPESTPI 1695


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 81/311 (26%), Positives = 114/311 (36%), Gaps = 42/311 (13%)

Query: 12   SLSPDVPV--PSDHGG-TESSPGWGSSGPWSLSPSDSSPSGVTSRLPGRSTSLVEGRSCG 68
            S SP  P   P   GG T  SP +  + P S SP+  S S  +      S S     S  
Sbjct: 1592 SYSPTSPAYEPRSPGGYTPQSPSYSPTSP-SYSPTSPSYSPTSPNYSPTSPSY-SPTSPS 1649

Query: 69   WVPPPPGFAPLAPRLGPEL-SPSPTSPTATSTTPSRYKTELCRTFSESGRCRYGAKCQFA 127
            + P  P ++P +P   P   S SPTSP+ + T+PS   T    ++S +            
Sbjct: 1650 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS--PSYSPTSPS--------- 1698

Query: 128  HGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPVLRQSISF 187
                    +   P Y              P  S     ++P+    +P  P     S S+
Sbjct: 1699 -------YSPTSPSYSPT----------SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1741

Query: 188  SGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPG---TPLARRD 244
            S  P+    SP  P     S S S  SPS SP  P   P SP+    +P    T  +   
Sbjct: 1742 S--PTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSP 1799

Query: 245  PTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGSDSPVF--EAG 302
             +P   PS  R TP S          +PS  S      +Y  +  S   S SP +   + 
Sbjct: 1800 TSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPS-SPEYTPTSP 1858

Query: 303  VFAPPQPVAAP 313
             ++P  P  +P
Sbjct: 1859 KYSPTSPKYSP 1869



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 65/246 (26%), Positives = 99/246 (40%), Gaps = 17/246 (6%)

Query: 20   PSDHGGTESSPGWGSSGPWSLSPSDSSPSGVTSRLPGRSTSLVEGRSCGWVPPPPGFAPL 79
            P+    + +SP +  + P S SP+  S S  +      S S     S  + P  P ++P 
Sbjct: 1645 PTSPSYSPTSPSYSPTSP-SYSPTSPSYSPTSPSYSPTSPSY-SPTSPSYSPTSPSYSPT 1702

Query: 80   APRLGPEL-SPSPTSPTATSTTPSRYKTELCRTFSESGRCRYGAKCQFAHGLGELRQANR 138
            +P   P   S SPTSP+ + T+PS   T    ++S +          ++         + 
Sbjct: 1703 SPSYSPTSPSYSPTSPSYSPTSPSYSPTS--PSYSPTSPSYSPTSPNYSPTSPNYTPTS- 1759

Query: 139  HPKYK-TELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPVLRQSISFSGLPSGRRTS 197
             P Y  T   +        P        ++P+    +P  P     S S+S  PS  R +
Sbjct: 1760 -PSYSPTSPSYSPTSPNYTPTSPN----YSPTSPSYSPTSPSYSPTSPSYS--PSSPRYT 1812

Query: 198  PPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPG-TPLA-RRDPT-PVCCPSCR 254
            P  P     S S S  SPS SP  P   P SPS   ++P  TP + +  PT P   P+  
Sbjct: 1813 PQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSP 1872

Query: 255  RATPIS 260
            + +P S
Sbjct: 1873 KYSPTS 1878



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 74/294 (25%), Positives = 111/294 (37%), Gaps = 27/294 (9%)

Query: 12   SLSPDVPV--PSDHGGTESSPGWGSSGPWSLSPSDSSPSGVTSRLPGRSTSLVEGRSCGW 69
            S SP  P   P+    + +SP +  + P S SP+  S S  +      S S     S  +
Sbjct: 1691 SYSPTSPSYSPTSPSYSPTSPSYSPTSP-SYSPTSPSYSPTSPSYSPTSPSY-SPTSPNY 1748

Query: 70   VPPPPGFAPLAPRLGPEL-SPSPTSPTATSTTPSRYKTELCRTFSESGRCRYGAKCQFAH 128
             P  P + P +P   P   S SPTSP  T T+P+   T      S S      +    ++
Sbjct: 1749 SPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSP----SYSPTSPSYSPTSPSY 1804

Query: 129  GLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPVLRQSISFS 188
                 R   + P Y              P  S     ++P+     P  P     S  ++
Sbjct: 1805 SPSSPRYTPQSPTYTPS----------SPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYT 1854

Query: 189  GLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAP-GTPLA-RRDPT 246
              P+  + SP  P  +  S   S  SP+ SP  P   P SP+    +P  TP + +  PT
Sbjct: 1855 --PTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPT 1912

Query: 247  -PVCCPSCRRATPIS-VWGPLGGLVRTPSVQSLGSDPDE--YASSGSSLGGSDS 296
             P   P+  + +P S  + P      T S  S G  P    Y+ +  ++   DS
Sbjct: 1913 SPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDS 1966



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 64/235 (27%), Positives = 86/235 (36%), Gaps = 34/235 (14%)

Query: 29   SPGW----GSSG-PWSLSPSDSSPSGVTSRLPGRSTSLVEGRSCGWVPPPPGFAPLAPRL 83
            SP W    GS G P   SP   SP G  S     ++   E RS      P G+ P +P  
Sbjct: 1562 SPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRS------PGGYTPQSP-- 1613

Query: 84   GPELSPSPTSPTATSTTPSRYKTELCRTFSESGRCRYGAKCQFAHGLGELRQANRHPKYK 143
                S SPTSP+ + T+PS   T     +S +          ++         +  P Y 
Sbjct: 1614 ----SYSPTSPSYSPTSPSYSPTS--PNYSPTSPSYSPTSPSYSPTSPSYSPTS--PSYS 1665

Query: 144  TELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPVLRQSISFSGLPSGRRTSPPPPGL 203
                         P  S     ++P+    +P  P     S S+S  P+    SP  P  
Sbjct: 1666 P----------TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS--PTSPSYSPTSPSY 1713

Query: 204  AGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPLARRDPTPVCCPSCRRATP 258
            +  S S S  SPS SP  P   P SPS    +P       + TP   PS    +P
Sbjct: 1714 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPT-SPSYSPTSP 1767


>gi|155722994 zinc finger CCCH-type containing 3 [Homo sapiens]
          Length = 948

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 51/173 (29%), Positives = 68/173 (39%), Gaps = 51/173 (29%)

Query: 105 KTELCRTFSESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHF 164
           K E+C  F + G C  GAKC+  H L               LC  F  +G CP G++C  
Sbjct: 752 KAEVCSDFLK-GYCPLGAKCKKKHTL---------------LCPDFARRGACPRGAQCQL 795

Query: 165 IH----------------NPSEDLA----APGHPP--------VLRQSISFSGLPSGRRT 196
           +H                 PS+  A    +  H P          RQ+ S + L +    
Sbjct: 796 LHRTQKRHSRRAATSPAPGPSDATARSRVSASHGPRKPSASQRPTRQTPSSAALTAAAVA 855

Query: 197 SPP--PPGLAGPSLSSSSFSPSSSPPPPGDL-----PLSPSAFSAAPGTPLAR 242
           +PP  P G A PS S +S S SSS  PP  L      L  +A +AA    L +
Sbjct: 856 APPHCPGGSASPSSSKASSSSSSSSSPPASLDHEAPSLQEAALAAACSNRLCK 908



 Score = 35.4 bits (80), Expect = 0.069
 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 9/88 (10%)

Query: 86  ELSPSPTSPTATSTTPSRYKTELCRT--FSESGRC-RYGAKCQFAHGLGELRQANRHPKY 142
           +LS +   P+   + P      L RT     +G C R  A       L  +RQA +  + 
Sbjct: 615 KLSKTSGQPSDAGSRP------LLRTGRLDPAGSCSRSLASRAVQRSLAIIRQARQRREK 668

Query: 143 KTELCHKFYLQGRCPYGSRCHFIHNPSE 170
           + E C  +   GRC  G RC +IH+P +
Sbjct: 669 RKEYCMYYNRFGRCNRGERCPYIHDPEK 696


>gi|122937239 zinc finger CCCH-type domain containing 5 [Homo
           sapiens]
          Length = 886

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 45/155 (29%), Positives = 65/155 (41%), Gaps = 32/155 (20%)

Query: 112 FSESGRCRYGAKCQFAHGLGELRQANRHPK-YKTELCHKFYLQGRCPYGSRCHFIH---- 166
           + + G+C  G  CQ+ H   E +    HP+ YK+  C+     G CP G  C F H    
Sbjct: 342 WGDPGKCENGDACQYCHTRTEQQF---HPEIYKSTKCNDMQQSGSCPRGPFCAFAHVEQP 398

Query: 167 ------NPSEDLAAPGHP-PVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSF-SPSS- 217
                  PS  +++P  P PVL    +         +SP  P L+     +SS  SPS+ 
Sbjct: 399 PLSDDLQPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSSPHAPDLSALLCRNSSLGSPSNL 458

Query: 218 --SPPP-------------PGDLPLSPSAFSAAPG 237
             SPP              PG+  L+P ++  APG
Sbjct: 459 CGSPPGSIRKPPNLEGIVFPGESGLAPGSYKKAPG 493



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 50/191 (26%), Positives = 76/191 (39%), Gaps = 21/191 (10%)

Query: 97  TSTTPSRYKTELCRTFSESGRCRYGAKCQFAHGLGELRQANRHPKYKTELC------HKF 150
           T+     YKTE C+       CR G  C + H   + R++ R  KY++  C       ++
Sbjct: 285 TAYVLGNYKTEPCK--KPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEW 342

Query: 151 YLQGRCPYGSRCHFIHNPSEDLAAPGHPPVLRQSISFSGLPSGRRTSPPPPGLA---GPS 207
              G+C  G  C + H  +E      HP + + +       SG     P    A    P 
Sbjct: 343 GDPGKCENGDACQYCHTRTEQ---QFHPEIYKSTKCNDMQQSGSCPRGPFCAFAHVEQPP 399

Query: 208 LSS--SSFSPSSSPPPPGDLPLSPSA----FSAAPGTPLARRDPTPVCCPSCRRATPISV 261
           LS      S  SSP  PG +   PSA       +P +P A  D + + C +    +P ++
Sbjct: 400 LSDDLQPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSSPHA-PDLSALLCRNSSLGSPSNL 458

Query: 262 WGPLGGLVRTP 272
            G   G +R P
Sbjct: 459 CGSPPGSIRKP 469



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 23/62 (37%), Positives = 28/62 (45%), Gaps = 7/62 (11%)

Query: 80  APRLGPELSPSPTSPTATSTTPSRY-----KTELCRTFSES-GRC-RYGAKCQFAHGLGE 132
           A  L PE    P     T  T  RY     KT +C   ++S G C + G  C FAHG  +
Sbjct: 172 ATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHD 231

Query: 133 LR 134
           LR
Sbjct: 232 LR 233


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 54/193 (27%), Positives = 74/193 (38%), Gaps = 51/193 (26%)

Query: 168 PSEDLAAPGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSP------------ 215
           P   +  P  PP L  S+   G+P    ++ PPP L  PSLSS+   P            
Sbjct: 556 PPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAP 615

Query: 216 ---------SSSPPPPGDLPLS-----PSAFSAAPGTPLAR-------RDPTPVCCPSCR 254
                    SS+ PPPG  P       P   +AAP  P +          P P   P   
Sbjct: 616 PPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLP--- 672

Query: 255 RATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLG---------GSDSPVFEAGVFA 305
             TP+S +G        P +QS G  P E  +S + L           SD  + E+   A
Sbjct: 673 --TPVS-FGSAPPTTYHPPLQSAG--PSEQVNSKAPLSKSALPYSSFSSDQGLGESSA-A 726

Query: 306 PPQPVAAPRRLPI 318
           P QP+ A + +P+
Sbjct: 727 PSQPITAVKDMPV 739



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 33/107 (30%), Positives = 45/107 (42%), Gaps = 10/107 (9%)

Query: 178 PPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPG 237
           PPVL  S+    +P     + PPPG+  P +  S   P+S PPP   +P S S+    P 
Sbjct: 535 PPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPS--LPTSVPPP--GMPPSLSSAGPPPV 590

Query: 238 TP---LARRDPTPVCCPSCRRAT---PISVWGPLGGLVRTPSVQSLG 278
            P   L+   P PV  P    +T   P+    PL      P +   G
Sbjct: 591 LPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPG 637



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 65/264 (24%), Positives = 87/264 (32%), Gaps = 46/264 (17%)

Query: 72  PPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFSESGRCRYGAKCQFAHGLG 131
           PPP   P  P   PE SP P    ++STTP+   +    +F E               L 
Sbjct: 15  PPPPVPPPPPVALPEASPGPGY--SSSTTPAAPSSSGFMSFREQH-------------LA 59

Query: 132 ELRQANR-HPKYKTELCHKFYLQGR-------CPYGSRCHFIHNPSEDLAAPGHPPVLRQ 183
           +L+Q  + H K    +    +L           P G    +   P   +  P  P +  Q
Sbjct: 60  QLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDW-QPPPPPMPPPPGPALSYQ 118

Query: 184 SISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPLARR 243
                           PPGL    L S    P S P PPG       ++   P  P +  
Sbjct: 119 KQQQYKHQMLHHQRDGPPGLVPMELESP---PESPPVPPGSYMPPSQSYMPPPQPPPSYY 175

Query: 244 DPT------PVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSL--GGSD 295
            PT      P   PS  ++ P   +     L  TPS  S  S    Y S   S       
Sbjct: 176 PPTSSQPYLPPAQPSPSQSPPSQSY-----LAPTPSYSSSSSSSQSYLSHSQSYLPSSQA 230

Query: 296 SPV------FEAGVFAPPQPVAAP 313
           SP        ++ + APP P A P
Sbjct: 231 SPSRPSQGHSKSQLLAPPPPSAPP 254


>gi|31652264 RNA binding motif protein 26 [Homo sapiens]
          Length = 980

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 38/130 (29%), Positives = 48/130 (36%), Gaps = 25/130 (19%)

Query: 109 CRTFSESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNP 168
           CR + E G C  G  C F HG   +            +     L G  P+ ++   +  P
Sbjct: 294 CRDYDEKGFCMRGDMCPFDHGSDPV------------VVEDVNLPGMLPFPAQPPVVEGP 341

Query: 169 SEDLAAPGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLS 228
                 P  PP+L         P   R   PPPG   PSL      P + PPPP   PL 
Sbjct: 342 PPP-GLPPPPPILTPP------PVNLRPPVPPPGPLPPSL-----PPVTGPPPPLP-PLQ 388

Query: 229 PSAFSAAPGT 238
           PS   A P +
Sbjct: 389 PSGMDAPPNS 398


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 90/332 (27%), Positives = 113/332 (34%), Gaps = 63/332 (18%)

Query: 20  PSDHGGTE--SSPGWGSSGPWSLSPSDSSPSGV-TSRLPGRSTSLVEGRSCGWVPPPPGF 76
           PS  GG +  +S    SS     SP+ S PS   T R P    S  + +    + PP   
Sbjct: 219 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP-SQPKPKGLQALRPPQVT 277

Query: 77  AP---LAPRLGPELS-----------PSPTSPTATSTTPSRYKTELCRTFSESGRCRYGA 122
            P    AP LGP  S           PSP++P +  T PS   T   +  +  G     A
Sbjct: 278 PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 337

Query: 123 KCQF------------------AHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHF 164
              F                  A  L  L QA   P     L        + P     H 
Sbjct: 338 THSFLPSPPLSPLATPPPQAPPALALPPL-QAPPSPPASPPLSPLATPSPQAPNALAVHL 396

Query: 165 IHNPSEDLAAPGHPPVLRQSISFSGLPSGRRTSPP---PPGLAGPSLSSSSFSPSSSPPP 221
           +  P    + P  PPV       +  P     +PP   PP LA P L          P P
Sbjct: 397 LQAP---FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL-------QVPPSP 446

Query: 222 PGDLPLSPSAFSAAPGTPLARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDP 281
           P   P+SPSA      TP   + P P+  P  + A P     P    + TP +Q+L S P
Sbjct: 447 PASPPMSPSA------TP-PPQAPPPLAAPPLQLAKPPPQAPP---ALATPPLQALPSPP 496

Query: 282 DEYASSGSSLGGSDSPVFEAGVFAPPQPVAAP 313
              AS       S S        A P P A P
Sbjct: 497 ---ASFPGQAPFSPSASLPMSPLATPPPQAPP 525



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 44/160 (27%), Positives = 58/160 (36%), Gaps = 34/160 (21%)

Query: 169 SEDLAAPGHPPVLRQSISFSG--LPSGRRTSPPPPG-------LAGPSLSSSSFSPSSSP 219
           S  L AP  PP      S SG  L       PPPP        L+GP L+  S S +S+P
Sbjct: 541 SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 600

Query: 220 P----------------PPGDLPLS---PSAFSAAPGTPLARRDPTPVCCPSCRRATP-- 258
                            PP D  L+   P+A+S  P  PLA R       P      P  
Sbjct: 601 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS 660

Query: 259 ----ISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGS 294
                +++   G    TP+  +L   P    S G +  G+
Sbjct: 661 ADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA 700



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 54/175 (30%), Positives = 67/175 (38%), Gaps = 34/175 (19%)

Query: 168 PSEDLAAPGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSP-----PPP 222
           P    A P  PP     ++   L   +     PP LA P L +    P+S P      P 
Sbjct: 451 PMSPSATP--PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 508

Query: 223 GDLPLSPSAF---SAAP--GTPLARRDPTPVCCPSC----RRATP---ISVWGPLGGLV- 269
             LP+SP A     A P    PL +  P+P   P+     R  TP    SV GP   L  
Sbjct: 509 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL 568

Query: 270 ---------RTPSVQSLGSDPDEYASSGSS----LGGSDSPVFEAGVFAPPQPVA 311
                    R+PS    G D   ++SS +S    L G DS   E G  A P P A
Sbjct: 569 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGP-EGGAAASPPPDA 622



 Score = 32.0 bits (71), Expect = 0.77
 Identities = 81/345 (23%), Positives = 115/345 (33%), Gaps = 53/345 (15%)

Query: 18  PVPSDHGGTESSPGWGSS----GPWS-----LSPSDSSPSGVTSRLPGRSTSLVEGR--S 66
           P  +   G  SSPG  S     GP       +S  ++   G  +  P RS      R  +
Sbjct: 96  PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT 155

Query: 67  CGWVP--PPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFSESGRCRYG--A 122
            G  P  P P  A  +   G E+     +P+A    P+    +   + SE         A
Sbjct: 156 SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA 215

Query: 123 KCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPVLR 182
           + + + G G  R A+R                  P  S      +      AP HP   +
Sbjct: 216 RRRPSAGGGLQRPASRSLS-----------SSATPLSSPARSGPSARGTPRAPAHPSQPK 264

Query: 183 QSISFSGLPSGRRTSPPPPG-----LAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPG 237
                 GL + R     PP        GP  SS   +PS S PP    P S     + P 
Sbjct: 265 PK----GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPA 320

Query: 238 TPLARRDPTPVCCPSCRRATPISVWGPLGGLVRTP-------SVQSLGSDPDEYASSGSS 290
           TP ++   T +  P+ +         PL  L   P       ++  L + P   AS   S
Sbjct: 321 TPPSQA-TTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS 379

Query: 291 LGGSDSP---------VFEAGVFAPPQ-PVAAPRRLPIFNRISVS 325
              + SP         + +A    PP  PV AP   P    +S S
Sbjct: 380 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 78/315 (24%), Positives = 105/315 (33%), Gaps = 55/315 (17%)

Query: 44  DSSPSGVTSRLPG-RSTSLVEGRSCGWVPPPP----------------GFAPLAPRLG-- 84
           D + +G  +R P  R+  L+  R  G   PPP                G  PLA R G  
Sbjct: 6   DKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI 65

Query: 85  -----PELSPSPTSPTATSTTPSRYKTELCRTFSESGRCRYGAKCQFAHGLGELRQANRH 139
                PE +P    PT TS  P+  + E       +     G         G  R     
Sbjct: 66  GGATIPESAPR-AGPTRTSRPPASGRGERAPPAKNTSP---GPVSSPGRASGTTRPGPLG 121

Query: 140 PKYKTELCHKFYLQGRCPYG-SRCHFIHNPSEDLAAPG----HPPVLRQSISFS---GLP 191
            K       +   +G+      R         D + P      P + R+S +     GLP
Sbjct: 122 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 181

Query: 192 SGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSA--APGTPLARRDPTPVC 249
               ++ P P   GP  S SS S  S+  P       PSA      P +       TP+ 
Sbjct: 182 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 241

Query: 250 CPS----CRRATPISVWGPL----GGL--VRTPSVQSLGSDPDEYASSGSSLGG-SDSPV 298
            P+      R TP +   P      GL  +R P V     D      +  +LG  S SP+
Sbjct: 242 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD------AAPALGPLSSSPL 295

Query: 299 FEAGVFAPPQPVAAP 313
                 APP P A P
Sbjct: 296 ATPSPSAPPSPSAPP 310


>gi|32880199 makorin ring finger protein 2 [Homo sapiens]
          Length = 416

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 34/93 (36%), Positives = 45/93 (48%), Gaps = 16/93 (17%)

Query: 109 CRTFSESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNP 168
           CR F   G CR G++C F+H L     AN  P   + +C K+Y +G C YG+RC + H  
Sbjct: 8   CRYFMH-GVCREGSQCLFSHDL-----ANSKP---STIC-KYYQKGYCAYGTRCRYDHT- 56

Query: 169 SEDLAAPGHPPVLRQSISFSGLPSGRRTSPPPP 201
               AA G    +  S+     PS    SP PP
Sbjct: 57  RPSAAAGGAVGTMAHSV-----PSPAFHSPHPP 84



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 6/44 (13%)

Query: 149 KFYLQGR--CPYGSRCHFIH-NPSEDLAAPGHPPVLRQSISFSG 189
           K++ QG+  CP+GS+C + H  P   LA P  P   R+ +S  G
Sbjct: 328 KYFEQGKGTCPFGSKCLYRHAYPDGRLAEPEKP---RKQLSSQG 368


>gi|239788462 dihydrouridine synthase 3-like isoform 1 [Homo
           sapiens]
          Length = 650

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 47/182 (25%), Positives = 70/182 (38%), Gaps = 43/182 (23%)

Query: 101 PSRY-KTELCRTFSE--SGRCRYGAKCQFAHGLG---ELRQANRHPKYKTELCHKFYLQG 154
           P+ Y K  LC +  +  + +C +G +C+F H +G   E + A+  P+     C  F   G
Sbjct: 115 PTNYDKNRLCPSLIQESAAKCFFGDRCRFLHDVGRYLETKPADLGPR-----CVLFETFG 169

Query: 155 RCPYGSRCHFI---------HNPSEDLAAPG-HPPVLR-------------QSISFSGLP 191
           RCPYG  C F          +   E+LAA G  PP +R             + + F    
Sbjct: 170 RCPYGVTCRFAGAHLRPEGQNLVQEELAARGTQPPSIRNGLDKALQQQLRKREVRFERAE 229

Query: 192 SGRR--TSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPLARRDPTPVC 249
              R  +  P P  A P  +++  +P         +P       A PGT      P   C
Sbjct: 230 QALRRFSQGPTPAAAVPEGTAAEGAPRQENCGAQQVP-------AGPGTSTPPSSPVRTC 282

Query: 250 CP 251
            P
Sbjct: 283 GP 284


>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 33/107 (30%), Positives = 48/107 (44%), Gaps = 4/107 (3%)

Query: 175 PGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSA 234
           P  PP L  ++S S L +   ++PPPP    P   +++    + PPPP  L ++P     
Sbjct: 325 PPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHP 384

Query: 235 APGTPLARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDP 281
           AP  P+A   P     P   RA P+    P+  L +   VQ L   P
Sbjct: 385 AP-PPIA--PPLVQPSPPVARAAPVCETVPVHPLPQ-GEVQGLPPPP 427



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 14/84 (16%)

Query: 196 TSPPPPGLAGPSLSSSSF--SPSSSPPPPGDLPLSPSAFS-AAPGTP-----------LA 241
           T PPPP     +LS+SS   S +S+PPPP   P  P A +  AP  P           + 
Sbjct: 323 TPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVL 382

Query: 242 RRDPTPVCCPSCRRATPISVWGPL 265
              P P+  P  + + P++   P+
Sbjct: 383 HPAPPPIAPPLVQPSPPVARAAPV 406



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 13/80 (16%)

Query: 178 PPVLR-----QSISFSGLPSGRRTS----PPPPGLAGPSL-SSSSFSPSSSPPPPGDLPL 227
           PPV R     +++    LP G        PPPP L  P +  SS  + ++   PP  L  
Sbjct: 398 PPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHP 457

Query: 228 SPSAFSAAPGTPLARRDPTP 247
           +P   S APG  +    P+P
Sbjct: 458 TP---STAPGPHVPLMPPSP 474


>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 33/107 (30%), Positives = 48/107 (44%), Gaps = 4/107 (3%)

Query: 175 PGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSA 234
           P  PP L  ++S S L +   ++PPPP    P   +++    + PPPP  L ++P     
Sbjct: 325 PPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHP 384

Query: 235 APGTPLARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDP 281
           AP  P+A   P     P   RA P+    P+  L +   VQ L   P
Sbjct: 385 AP-PPIA--PPLVQPSPPVARAAPVCETVPVHPLPQ-GEVQGLPPPP 427



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 14/84 (16%)

Query: 196 TSPPPPGLAGPSLSSSSF--SPSSSPPPPGDLPLSPSAFS-AAPGTP-----------LA 241
           T PPPP     +LS+SS   S +S+PPPP   P  P A +  AP  P           + 
Sbjct: 323 TPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVL 382

Query: 242 RRDPTPVCCPSCRRATPISVWGPL 265
              P P+  P  + + P++   P+
Sbjct: 383 HPAPPPIAPPLVQPSPPVARAAPV 406



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 13/80 (16%)

Query: 178 PPVLR-----QSISFSGLPSGRRTS----PPPPGLAGPSL-SSSSFSPSSSPPPPGDLPL 227
           PPV R     +++    LP G        PPPP L  P +  SS  + ++   PP  L  
Sbjct: 398 PPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHP 457

Query: 228 SPSAFSAAPGTPLARRDPTP 247
           +P   S APG  +    P+P
Sbjct: 458 TP---STAPGPHVPLMPPSP 474


>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 33/107 (30%), Positives = 48/107 (44%), Gaps = 4/107 (3%)

Query: 175 PGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSA 234
           P  PP L  ++S S L +   ++PPPP    P   +++    + PPPP  L ++P     
Sbjct: 325 PPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHP 384

Query: 235 APGTPLARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDP 281
           AP  P+A   P     P   RA P+    P+  L +   VQ L   P
Sbjct: 385 AP-PPIA--PPLVQPSPPVARAAPVCETVPVHPLPQ-GEVQGLPPPP 427



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 14/84 (16%)

Query: 196 TSPPPPGLAGPSLSSSSF--SPSSSPPPPGDLPLSPSAFS-AAPGTP-----------LA 241
           T PPPP     +LS+SS   S +S+PPPP   P  P A +  AP  P           + 
Sbjct: 323 TPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVL 382

Query: 242 RRDPTPVCCPSCRRATPISVWGPL 265
              P P+  P  + + P++   P+
Sbjct: 383 HPAPPPIAPPLVQPSPPVARAAPV 406



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 13/80 (16%)

Query: 178 PPVLR-----QSISFSGLPSGRRTS----PPPPGLAGPSL-SSSSFSPSSSPPPPGDLPL 227
           PPV R     +++    LP G        PPPP L  P +  SS  + ++   PP  L  
Sbjct: 398 PPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHP 457

Query: 228 SPSAFSAAPGTPLARRDPTP 247
           +P   S APG  +    P+P
Sbjct: 458 TP---STAPGPHVPLMPPSP 474


>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 33/107 (30%), Positives = 48/107 (44%), Gaps = 4/107 (3%)

Query: 175 PGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSA 234
           P  PP L  ++S S L +   ++PPPP    P   +++    + PPPP  L ++P     
Sbjct: 325 PPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHP 384

Query: 235 APGTPLARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDP 281
           AP  P+A   P     P   RA P+    P+  L +   VQ L   P
Sbjct: 385 AP-PPIA--PPLVQPSPPVARAAPVCETVPVHPLPQ-GEVQGLPPPP 427



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 14/84 (16%)

Query: 196 TSPPPPGLAGPSLSSSSF--SPSSSPPPPGDLPLSPSAFS-AAPGTP-----------LA 241
           T PPPP     +LS+SS   S +S+PPPP   P  P A +  AP  P           + 
Sbjct: 323 TPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVL 382

Query: 242 RRDPTPVCCPSCRRATPISVWGPL 265
              P P+  P  + + P++   P+
Sbjct: 383 HPAPPPIAPPLVQPSPPVARAAPV 406



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 13/80 (16%)

Query: 178 PPVLR-----QSISFSGLPSGRRTS----PPPPGLAGPSL-SSSSFSPSSSPPPPGDLPL 227
           PPV R     +++    LP G        PPPP L  P +  SS  + ++   PP  L  
Sbjct: 398 PPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHP 457

Query: 228 SPSAFSAAPGTPLARRDPTP 247
           +P   S APG  +    P+P
Sbjct: 458 TP---STAPGPHVPLMPPSP 474


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 76/299 (25%), Positives = 103/299 (34%), Gaps = 53/299 (17%)

Query: 39  SLSPSDSSPSGVTSRLPGRSTSLVEGRSCGWVPPPPGFAPLAPRLG---PELSPSPTSPT 95
           +L P  SSP    S      ++ ++ ++   +P  P  + L  +L    P   PSP++P 
Sbjct: 295 ALGPLSSSPLATPS-----PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPP 349

Query: 96  ATSTTPSRYKTELCRTFSESGRCRYGAKCQF------------------AHGLGELRQAN 137
           +  T PS   T   +  +  G     A   F                  A  L  L QA 
Sbjct: 350 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL-QAP 408

Query: 138 RHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPVLRQSISFSGLPSGRRTS 197
             P     L        + P     H +  P    + P  PPV       +  P     +
Sbjct: 409 PSPPASPPLSPLATPSPQAPNALAVHLLQAP---FSPPPSPPVQAPFSPPASPPVSPSAT 465

Query: 198 PP---PPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPLARRDPTPVCCPSCR 254
           PP   PP LA P L          P PP   P+SPSA      TP   + P P+  P  +
Sbjct: 466 PPSQAPPSLAAPPL-------QVPPSPPASPPMSPSA------TP-PPQAPPPLAAPPLQ 511

Query: 255 RATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGSDSPVFEAGVFAPPQPVAAP 313
            A P     P    + TP +Q+L S P   AS       S S        A P P A P
Sbjct: 512 LAKPPPQAPP---ALATPPLQALPSPP---ASFPGQAPFSPSASLPMSPLATPPPQAPP 564



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 44/160 (27%), Positives = 58/160 (36%), Gaps = 34/160 (21%)

Query: 169 SEDLAAPGHPPVLRQSISFSG--LPSGRRTSPPPPG-------LAGPSLSSSSFSPSSSP 219
           S  L AP  PP      S SG  L       PPPP        L+GP L+  S S +S+P
Sbjct: 580 SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 639

Query: 220 P----------------PPGDLPLS---PSAFSAAPGTPLARRDPTPVCCPSCRRATP-- 258
                            PP D  L+   P+A+S  P  PLA R       P      P  
Sbjct: 640 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS 699

Query: 259 ----ISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGS 294
                +++   G    TP+  +L   P    S G +  G+
Sbjct: 700 ADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA 739



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 79/317 (24%), Positives = 112/317 (35%), Gaps = 46/317 (14%)

Query: 18  PVPSDHGGTESSPGWGSS----GPWS-----LSPSDSSPSGVTSRLPGRSTSLVEGR--S 66
           P  +   G  SSPG  S     GP       +S  ++   G  +  P RS      R  +
Sbjct: 105 PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT 164

Query: 67  CGWVP--PPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFSESGRCRYG--A 122
            G  P  P P  A  +   G E+     +P+A    P+    +   + SE         A
Sbjct: 165 SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA 224

Query: 123 KCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPVLR 182
           + + + G G  R A+R                  P  S      +      AP HP   +
Sbjct: 225 RRRPSAGGGLQRPASRSLS-----------SSATPLSSPARSGPSARGTPRAPAHPSQPK 273

Query: 183 QSISFSGLPSGRRTSPPPPGL-AGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPLA 241
                 GL + R     PP   A P+L   S SP ++P P     L   A    P TP +
Sbjct: 274 PK----GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP--SAALQSQAPPTLPATPHS 327

Query: 242 RRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEYASSG-SSLGGSDSPVFE 300
                     +C+ ATP+ +  P       PS+Q+L S P    S   +SLG   SP  +
Sbjct: 328 -------SSLTCQLATPLPLAPPSPS--APPSLQTLPSPPATPPSQATTSLG---SPTLQ 375

Query: 301 AGVFAPPQPVAAPRRLP 317
           A     P P  +P   P
Sbjct: 376 ATHSFLPSPPLSPLATP 392



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 54/175 (30%), Positives = 67/175 (38%), Gaps = 34/175 (19%)

Query: 168 PSEDLAAPGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSP-----PPP 222
           P    A P  PP     ++   L   +     PP LA P L +    P+S P      P 
Sbjct: 490 PMSPSATP--PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 547

Query: 223 GDLPLSPSAF---SAAP--GTPLARRDPTPVCCPSC----RRATP---ISVWGPLGGLV- 269
             LP+SP A     A P    PL +  P+P   P+     R  TP    SV GP   L  
Sbjct: 548 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL 607

Query: 270 ---------RTPSVQSLGSDPDEYASSGSS----LGGSDSPVFEAGVFAPPQPVA 311
                    R+PS    G D   ++SS +S    L G DS   E G  A P P A
Sbjct: 608 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGP-EGGAAASPPPDA 661



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 44/154 (28%), Positives = 62/154 (40%), Gaps = 14/154 (9%)

Query: 174 APGHPPVLRQSISFSGLPSGRRTSP---PPPGLAGPSLSSSSFSPSSSPPP--PGDLPLS 228
           +P  PP L+   S    P  + T+    P        L S   SP ++PPP  P  L L 
Sbjct: 344 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 403

Query: 229 PSAFSAAPGTPLARRDPTPVCCPSCRRATPISV---WGPLGGLVRTPSVQSLGSDPDEYA 285
           P     AP +P A    +P+  PS +    ++V     P      +P VQ+  S P    
Sbjct: 404 P---LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP-PPSPPVQAPFSPPASPP 459

Query: 286 SSGSSLGGSDSPVFEAG--VFAPPQPVAAPRRLP 317
            S S+   S +P   A   +  PP P A+P   P
Sbjct: 460 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 27/76 (35%), Positives = 36/76 (47%), Gaps = 13/76 (17%)

Query: 193 GRRTSPPPPGLAGPSLSS--SSFSPSSSPPPPGDLPLSPSAFSAAPGTPLARRDPTPVCC 250
           G  T P     AGP+ S+  SS +P+S PP  G    +P A + +PG         PV  
Sbjct: 66  GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG---------PVSS 116

Query: 251 PSCRRATPISVWGPLG 266
           P   RA+  +  GPLG
Sbjct: 117 PG--RASGTTRPGPLG 130


>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
          Length = 962

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 68/266 (25%), Positives = 94/266 (35%), Gaps = 33/266 (12%)

Query: 15  PDVPVPSDHGGTESSPGWGS-SGPWSLSPSDSSPSGVTSRLPGRSTSLVEGRSCGWVPPP 73
           P  P P      E+ P  G+ + P  +    + PS   +  P    S ++ R       P
Sbjct: 453 PPGPAPEPEREAETEPERGAGTEPERIG---TEPSTAPAPSPPAPKSCLKHRPAAASEGP 509

Query: 74  PGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFSESGRCRYGAKCQFAHGLGEL 133
               PLA    P + P P S  A +  P R K E       +G  R   + +   G  EL
Sbjct: 510 AASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEA-PPAGAERAAPERKAERGGAEL 568

Query: 134 RQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPVLRQSIS---FSGL 190
           R A    K+    C         P       +   S  L      PV R   +     GL
Sbjct: 569 RGAK---KFSVSSCR------ARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGL 619

Query: 191 PSGRRTSPPPPGLA--GPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPLARRDPTPV 248
           P  +   P P  LA  GP     S   ++SP  P     SP   +AAPGT    R+P   
Sbjct: 620 PEPQHAKPGPRKLAERGP---QDSGDRAASPAGPRK---SPQEAAAAPGT----REP--- 666

Query: 249 CCPSCRRATPISVWGPLGGLVRTPSV 274
            CP+ +   P     P    +R+ S+
Sbjct: 667 -CPAAQEPAPSEDRNPFPVKLRSTSL 691


>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
            potassium channel 4 [Homo sapiens]
          Length = 1203

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 40/138 (28%), Positives = 56/138 (40%), Gaps = 17/138 (12%)

Query: 191  PSGRRTSPPPPGLAG------------PSLSSSSFSPSSSPPPPGDLPLS-PSAFSAAPG 237
            P   + SP PPG  G            PS  S S SP     PPG+L L   +   + P 
Sbjct: 936  PQAAQPSPAPPGARGGLGLPEHFLPPPPSSRSPSSSPGQLGQPPGELSLGLATGPLSTPE 995

Query: 238  TPLARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGSDSP 297
            TP  + +P  +   +   A+P+  + P GGL  +P   S G  P  + S+     GS   
Sbjct: 996  TPPRQPEPPSLVAGASGGASPVG-FTPRGGL--SPPGHSPG-PPRTFPSAPPRASGSHGS 1051

Query: 298  VFEAGVFAPPQPVAAPRR 315
            +      +PP P    RR
Sbjct: 1052 LLLPPASSPPPPQVPQRR 1069



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 45/152 (29%), Positives = 59/152 (38%), Gaps = 35/152 (23%)

Query: 168  PSEDLAAPGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPP----- 222
            P   L+ PGH P         G P   RT P  P  A  S  S    P+SSPPPP     
Sbjct: 1021 PRGGLSPPGHSP---------GPP---RTFPSAPPRASGSHGSLLLPPASSPPPPQVPQR 1068

Query: 223  -GDLPLSPSAFSAAPGTPLARRDPTPV-CCPSCRRATPISVWGPLGGLVRTPSVQSLGSD 280
             G  PL+P   +       A +   P     + RRA+P S            S +S+ + 
Sbjct: 1069 RGTPPLTPGRLTQDLKLISASQPALPQDGAQTLRRASPHS------------SGESMAAF 1116

Query: 281  PDEYASSGSSLGGSDSPVFEAGVFAPPQPVAA 312
            P  +  +G   GGS S     G+  P +P  A
Sbjct: 1117 P-LFPRAGGGSGGSGS---SGGLGPPGRPYGA 1144



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 67/242 (27%), Positives = 82/242 (33%), Gaps = 40/242 (16%)

Query: 17   VPVPSDHGGTESSPGWGSSGPWSLSPSDSSPSGVTSRLPGRST---SLVEGRSCGWVP-- 71
            +P P       SSPG     P  LS   ++    T   P R     SLV G S G  P  
Sbjct: 959  LPPPPSSRSPSSSPGQLGQPPGELSLGLATGPLSTPETPPRQPEPPSLVAGASGGASPVG 1018

Query: 72   -------PPPGFAPLAPRLGPELSPSPTS-------PTATSTTPSRYKTELCRTFSESGR 117
                    PPG +P  PR  P   P  +        P A+S  P +            GR
Sbjct: 1019 FTPRGGLSPPGHSPGPPRTFPSAPPRASGSHGSLLLPPASSPPPPQVPQRRGTPPLTPGR 1078

Query: 118  CRYGAKCQFA-------HGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSE 170
                 K   A        G   LR+A+ H     E    F L  R   GS        S 
Sbjct: 1079 LTQDLKLISASQPALPQDGAQTLRRASPHS--SGESMAAFPLFPRAGGGSGG---SGSSG 1133

Query: 171  DLAAPGHPPVLRQSISFSGLPSGRRTS----PPPPGLAGPSLSSSSFSPSSSPP--PPGD 224
             L  PG P     +I    +   R+TS    PPP  L G   +SS   P ++ P   PG 
Sbjct: 1134 GLGPPGRP---YGAIPGQHVTLPRKTSSGSLPPPLSLFGARATSSGGPPLTAGPQREPGA 1190

Query: 225  LP 226
             P
Sbjct: 1191 RP 1192



 Score = 33.1 bits (74), Expect = 0.34
 Identities = 18/43 (41%), Positives = 21/43 (48%), Gaps = 1/43 (2%)

Query: 200 PPGLAG-PSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPLA 241
           PPGLA  P    +S  P++SPPPP   P   SA    P    A
Sbjct: 145 PPGLAAEPERPGASAQPAASPPPPQQPPQPASASCEQPSVDTA 187



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 53/212 (25%), Positives = 77/212 (36%), Gaps = 55/212 (25%)

Query: 45   SSPSGVTSRLPGRSTSLVEGRSCGWVPPPPGFAPLAPRLGPELSPSPTSPTATSTTPS-- 102
            S+P+G++  LP  S+S           PPPG        G   +P+P++  A +T     
Sbjct: 866  SAPAGLSPLLPSSSSS-----------PPPGAC------GSPSAPTPSAGVAATTIAGFG 908

Query: 103  RYKTELCRTFSESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRC 162
             +   L  + S S           +  L  L+   R P+               P G+R 
Sbjct: 909  HFHKALGGSLSSSD----------SPLLTPLQPGARSPQAAQP--------SPAPPGARG 950

Query: 163  ------HFIHNPSEDLAAPGHPPVLRQ-----SISFSGLPSGRRTSPP----PPGL-AGP 206
                  HF+  P    +    P  L Q     S+  +  P     +PP    PP L AG 
Sbjct: 951  GLGLPEHFLPPPPSSRSPSSSPGQLGQPPGELSLGLATGPLSTPETPPRQPEPPSLVAGA 1010

Query: 207  SLSSS--SFSPSSSPPPPGDLPLSPSAFSAAP 236
            S  +S   F+P     PPG  P  P  F +AP
Sbjct: 1011 SGGASPVGFTPRGGLSPPGHSPGPPRTFPSAP 1042


>gi|40548415 dishevelled associated activator of morphogenesis 2
           [Homo sapiens]
          Length = 1067

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 29/70 (41%), Positives = 34/70 (48%), Gaps = 11/70 (15%)

Query: 188 SGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLS----PSAFSAAPGTPLARR 243
           S L +G  +SPPPPG  GP   SSS + +  PPPP  LP +    P      PG P    
Sbjct: 512 SELSTGPVSSPPPPG--GPLTLSSSMTTNDLPPPPPPLPFACCPPPPPPPLPPGGP---- 565

Query: 244 DPTPVCCPSC 253
            PTP   P C
Sbjct: 566 -PTPPGAPPC 574



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 7/47 (14%)

Query: 208 LSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPLARRDPTPV---CCP 251
           LS  S  P SSPPPPG     P   S++  T      P P+   CCP
Sbjct: 511 LSELSTGPVSSPPPPG----GPLTLSSSMTTNDLPPPPPPLPFACCP 553


>gi|118766347 zinc finger CCCH-type domain containing 6 [Homo
           sapiens]
          Length = 1189

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 25/61 (40%), Positives = 35/61 (57%), Gaps = 10/61 (16%)

Query: 107 ELCRTFSESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIH 166
           ++C+ F E GRC  G +C+F H   EL +       + E+C KFYLQG C  G  C ++H
Sbjct: 276 QICKYFLE-GRCIKGDQCKFDHD-AELEK-------RKEIC-KFYLQGYCTKGENCIYMH 325

Query: 167 N 167
           N
Sbjct: 326 N 326



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 29/91 (31%), Positives = 37/91 (40%), Gaps = 18/91 (19%)

Query: 168 PSEDLAAP--GHPPVLRQSISFSGLPSGRRTSPPP---------PGLAGPSLSSSSFSPS 216
           P+ DLA      PP    S S  G P  + +SP P         PG  GP++S    SP 
Sbjct: 436 PTVDLAHKIGRKPPAFYTSASPPG-PQFQGSSPHPQHIYSSGSSPG-PGPNMSQGHSSPV 493

Query: 217 SSPPPPGDLPLSPSAFSAAPGTPLARRDPTP 247
             P  PG  P      +  PG P+ +  P P
Sbjct: 494 MHPGSPGHHPC-----AGPPGLPVPQSPPLP 519



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 12/32 (37%), Positives = 21/32 (65%), Gaps = 1/32 (3%)

Query: 137 NRHP-KYKTELCHKFYLQGRCPYGSRCHFIHN 167
           N+H  ++K +   K++L+GRC  G +C F H+
Sbjct: 266 NQHTVEHKGKQICKYFLEGRCIKGDQCKFDHD 297


>gi|194272180 plexin B1 [Homo sapiens]
          Length = 2135

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 36/110 (32%), Positives = 44/110 (40%), Gaps = 10/110 (9%)

Query: 197 SPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPLARRDPTPVCCPSCRRA 256
           SP PP   GPS S  +   + + P P  LP+ P A S A  +     D +P   PS    
Sbjct: 681 SPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATAS-----DISPGASPSL--- 732

Query: 257 TPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGSDSPVFEAGVFAP 306
             +S WGP  G     S  S GS   E  S  S   G  + V     F P
Sbjct: 733 --LSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP 780



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 48/169 (28%), Positives = 66/169 (39%), Gaps = 27/169 (15%)

Query: 169 SEDLAAPGHPPVLRQSISF---SGLPSGRRTSPPPP----GLAGPSLSSSSFSPSSSPPP 221
           S  L +P  P     SIS    +G P     SPP P    G A P+   + F PS++P  
Sbjct: 729 SPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPA--PTDFRPSATPED 786

Query: 222 PGDLPLSPSAFSAAPGT---PLARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLG 278
               PLSPS  +A P     P A     P+  P      P + +    G V+ P++  L 
Sbjct: 787 LLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPA--TVPATTFPGAMGSVK-PALDWLT 843

Query: 279 SDPDEYASSGSSLGGSDSPVF-----------EAGVFAPPQPVAAPRRL 316
            +  E   +    GG D+P F            A +  PP P+  P  L
Sbjct: 844 REGGELPEADEWTGG-DAPAFSTSTLLSGDGDSAELEGPPAPLILPSSL 891



 Score = 32.7 bits (73), Expect = 0.45
 Identities = 34/105 (32%), Positives = 46/105 (43%), Gaps = 13/105 (12%)

Query: 8   ESLLSLSPD-VPV----PSDHGGTESSPGWGSS-----GPWSLSPSDSSPSGVTSRLPGR 57
           ++L + +PD +PV    PS    ++ SPG   S     GPW+ S S SSP    S L   
Sbjct: 699 KALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEE 758

Query: 58  STSLVEGRSCGW-VPPPPGFAPLAPRLGPELSPSPTSPTATSTTP 101
            +        G  VP P  F P A     +L  SP SP+  +  P
Sbjct: 759 PSPPSPQNGPGTAVPAPTDFRPSA--TPEDLLASPLSPSEVAAVP 801


>gi|40254442 plexin B1 [Homo sapiens]
          Length = 2135

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 36/110 (32%), Positives = 44/110 (40%), Gaps = 10/110 (9%)

Query: 197 SPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPLARRDPTPVCCPSCRRA 256
           SP PP   GPS S  +   + + P P  LP+ P A S A  +     D +P   PS    
Sbjct: 681 SPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATAS-----DISPGASPSL--- 732

Query: 257 TPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGSDSPVFEAGVFAP 306
             +S WGP  G     S  S GS   E  S  S   G  + V     F P
Sbjct: 733 --LSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP 780



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 48/169 (28%), Positives = 66/169 (39%), Gaps = 27/169 (15%)

Query: 169 SEDLAAPGHPPVLRQSISF---SGLPSGRRTSPPPP----GLAGPSLSSSSFSPSSSPPP 221
           S  L +P  P     SIS    +G P     SPP P    G A P+   + F PS++P  
Sbjct: 729 SPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPA--PTDFRPSATPED 786

Query: 222 PGDLPLSPSAFSAAPGT---PLARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLG 278
               PLSPS  +A P     P A     P+  P      P + +    G V+ P++  L 
Sbjct: 787 LLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPA--TVPATTFPGAMGSVK-PALDWLT 843

Query: 279 SDPDEYASSGSSLGGSDSPVF-----------EAGVFAPPQPVAAPRRL 316
            +  E   +    GG D+P F            A +  PP P+  P  L
Sbjct: 844 REGGELPEADEWTGG-DAPAFSTSTLLSGDGDSAELEGPPAPLILPSSL 891



 Score = 32.7 bits (73), Expect = 0.45
 Identities = 34/105 (32%), Positives = 46/105 (43%), Gaps = 13/105 (12%)

Query: 8   ESLLSLSPD-VPV----PSDHGGTESSPGWGSS-----GPWSLSPSDSSPSGVTSRLPGR 57
           ++L + +PD +PV    PS    ++ SPG   S     GPW+ S S SSP    S L   
Sbjct: 699 KALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEE 758

Query: 58  STSLVEGRSCGW-VPPPPGFAPLAPRLGPELSPSPTSPTATSTTP 101
            +        G  VP P  F P A     +L  SP SP+  +  P
Sbjct: 759 PSPPSPQNGPGTAVPAPTDFRPSA--TPEDLLASPLSPSEVAAVP 801


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 38/131 (29%), Positives = 52/131 (39%), Gaps = 20/131 (15%)

Query: 168  PSEDLAAPGHPPVLRQSI------SFSGLPSGRRTSPPPPGLAGPSLSSSSFSP---SSS 218
            P  +   P  PPV  + +         G P+      P PG   P +  +  +P   S  
Sbjct: 1214 PEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPK 1273

Query: 219  PPPPGDLPLSPSAFSAAPGTPLARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLG 278
            PPPP   P +P    A  G P     P+P   PS  R  P ++  P G    TP   SLG
Sbjct: 1274 PPPP---PTAPKPVKAVAGLPSGSAGPSP--APSPARQPPAALAKPPG----TP--PSLG 1322

Query: 279  SDPDEYASSGS 289
            + P +  S G+
Sbjct: 1323 ASPAKPPSPGA 1333



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 47/204 (23%), Positives = 79/204 (38%), Gaps = 26/204 (12%)

Query: 26  TESSPGWGSS--GPWSLSPSDSSPSGVTSRLPGRSTSLVEGRSCGWVPPPPGFAPLAPR- 82
           T++ PG   +  GP   +P+ +        LP     +   RS    P   GFA + P+ 
Sbjct: 781 TKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTERPM-SPRSLPQSPTHRGFAYVLPQP 839

Query: 83  ----LGPELSPSPTSPTATSTTPSRYKTELC---RTFSESGRCRYGAKCQFAHGLGELRQ 135
               +GP  +P P  P   +  P+     LC      +E GR +     + AH L     
Sbjct: 840 VEGEVGPA-APGPAPPPVPTAVPT-----LCLPPEADAEPGRPK-----KRAHSLNRYAA 888

Query: 136 ANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPVLRQSISFSGLPSGRR 195
           ++  P+ + EL          PY +    +       A  G    + +S SF+  P  + 
Sbjct: 889 SDSEPE-RDEL---LVPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPRKKG 944

Query: 196 TSPPPPGLAGPSLSSSSFSPSSSP 219
             PPPP  +  +L+S++ +    P
Sbjct: 945 PPPPPPKRSSSALASANLADEPVP 968



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 48/195 (24%), Positives = 72/195 (36%), Gaps = 30/195 (15%)

Query: 71  PPPPGFAPL---APR--------LGPELSPSPTSPTATSTTPSRYKTELCRT-------- 111
           PPPP   P    +P+        L  EL  + T P     T  +  + L  T        
Sbjct: 634 PPPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHLPPTPRATTRQD 693

Query: 112 FSESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPY----GSRCHFIHN 167
            S  GR R+ +  Q   G G    ++   + +  L  +    G  P     G   H I  
Sbjct: 694 SSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPPREARPGRHGHSIKR 753

Query: 168 PSEDLAAPGHP-PVLRQSIS-FSGLPSGRRTSPPPP----GLAGPSLSSSSFSPSSSPPP 221
            S     PG P  VL    S F+   +  +T P  P    G  GP+ +++   P+    P
Sbjct: 754 ASVP-PVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLP 812

Query: 222 PGDLPLSPSAFSAAP 236
           P + P+SP +   +P
Sbjct: 813 PTERPMSPRSLPQSP 827



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 27/90 (30%), Positives = 34/90 (37%), Gaps = 18/90 (20%)

Query: 173  AAPGHPPVLRQSISFSGLPSGRRTS----------PPPPGLAGPSLSSSSFSPSSSPP-- 220
            A P  PP L  S+  +G  + RR            PPPP  A P  +  +  P   PP  
Sbjct: 1159 AGPEPPPPL--SVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEG 1216

Query: 221  ---PPGDLPLSPSAFSAAPGTPLARRDPTP 247
                P   P+SP      P  P  +  PTP
Sbjct: 1217 EARKPAKPPVSPKPVLTQP-VPKLQGSPTP 1245


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 38/131 (29%), Positives = 53/131 (40%), Gaps = 10/131 (7%)

Query: 188 SGLPSGRRTSPPPPGLAGPSLSSSSFSP--SSSPPPPGDLPLSPSAFSAAPGTPLARRDP 245
           S  P     +PP P    P+  SSS  P  +++PP P     +P + SA P T  A   P
Sbjct: 159 SPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAA--PP 216

Query: 246 TPVC---CPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGSDSPVFEAG 302
           TP      P    A P +   P      TP+  S  + P+  A   +    +  P   + 
Sbjct: 217 TPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDP---SS 273

Query: 303 VFAPPQPVAAP 313
             APP+  AAP
Sbjct: 274 ASAPPETTAAP 284



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 32/112 (28%), Positives = 43/112 (38%), Gaps = 3/112 (2%)

Query: 168 PSEDLAAPGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPL 227
           P E  AAP  P    Q+   S  P     +PP P    P+  SSS  P ++  PP     
Sbjct: 185 PPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSAT 244

Query: 228 SPSAFSAAPGTPLARRDPTPVCC---PSCRRATPISVWGPLGGLVRTPSVQS 276
           +P+  S++         PTP      PS   A P +   P      TP+  S
Sbjct: 245 TPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPS 296



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 41/147 (27%), Positives = 56/147 (38%), Gaps = 12/147 (8%)

Query: 168 PSEDLAAPGHPPVLRQSISFSGLPSGRRTSPPPPGL---AGPSLSSSSFSPSSSPPPPGD 224
           P +  AAP  P     +   S  P     +PP P     A PS S+   + ++ P PP  
Sbjct: 162 PQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPAT 221

Query: 225 LPLSPSAFSAAPGTPLARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEY 284
            P  PS+ SA P T  A   PT    PS     P+S   P       P+  +   DP   
Sbjct: 222 TPAPPSS-SAPPETTAA--PPT----PSATTPAPLSSSAPPETTAVPPTPSATTLDPSSA 274

Query: 285 ASSGSSLGGSDSPVFEAGVFAPPQPVA 311
           ++   +     +P   A   APP   A
Sbjct: 275 SAPPETTAAPPTP--SATTPAPPSSPA 299



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 31/110 (28%), Positives = 43/110 (39%), Gaps = 20/110 (18%)

Query: 168 PSEDLAAPGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSP------------ 215
           P E  AAP  PP    +   S  P     +PP P    P+  SSS  P            
Sbjct: 208 PPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSAT 267

Query: 216 ------SSSPPPPGDLPLSPSAFSAAPGTPLARRDPT--PVCCPSCRRAT 257
                 +S+PP     P +PSA + AP +  A ++ T  P+  P+    T
Sbjct: 268 TLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTT 317



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 14/103 (13%)

Query: 9   SLLSLSP-DVPVPSDHGGTESSPGWGSSGPWSLSPSDSSP---------SGVTSRLPGRS 58
           S+ +L+P + P P D      +P   +  P    PS S+P            T++ P  S
Sbjct: 150 SVATLAPVNSPAPQDTTAAPPTPSATTPAP----PSSSAPPETTAAPPTPSATTQAPPSS 205

Query: 59  TSLVEGRSCGWVPPPPGFAPLAPRLGPELSPSPTSPTATSTTP 101
           ++  E  +    PP    AP +    PE + +P +P+AT+  P
Sbjct: 206 SAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAP 248



 Score = 32.7 bits (73), Expect = 0.45
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 14/90 (15%)

Query: 15  PDVPVPSDHGGTESSPGWGSSGPWSLSPSDSSPSGVTSRLPGRSTSLVEGRSCGWVPPPP 74
           P  P  +    + S+P   ++ P   +PS ++P+ ++S  P  +T+         VPP P
Sbjct: 216 PTPPATTPAPPSSSAPPETTAAP--PTPSATTPAPLSSSAPPETTA---------VPPTP 264

Query: 75  GFAPLAPRLG---PELSPSPTSPTATSTTP 101
               L P      PE + +P +P+AT+  P
Sbjct: 265 SATTLDPSSASAPPETTAAPPTPSATTPAP 294



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 32/121 (26%), Positives = 49/121 (40%), Gaps = 9/121 (7%)

Query: 196 TSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPLARRDPTPVC---CPS 252
           TS     LA  +  +   + ++ P P    P  PS+ SA P T  A   PTP      P 
Sbjct: 147 TSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSS-SAPPETTAA--PPTPSATTQAPP 203

Query: 253 CRRATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGSDSPVFEAGVFAPPQPVAA 312
              A P +   P      TP+  S  + P+  A+  +    + +P+  +   APP+  A 
Sbjct: 204 SSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSS---APPETTAV 260

Query: 313 P 313
           P
Sbjct: 261 P 261



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 5/85 (5%)

Query: 18  PVPSDHGGTESSPGWGSSGPWSLSPSDSSPSGVTSRLPGRSTSLVEGRSCGWVPPPPGFA 77
           P PS    T  +P   S+ P + +   + P+  T+  P  S++  E  +    P     A
Sbjct: 193 PTPS---ATTQAPPSSSAPPETTAAPPTPPA--TTPAPPSSSAPPETTAAPPTPSATTPA 247

Query: 78  PLAPRLGPELSPSPTSPTATSTTPS 102
           PL+    PE +  P +P+AT+  PS
Sbjct: 248 PLSSSAPPETTAVPPTPSATTLDPS 272


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 90/349 (25%), Positives = 120/349 (34%), Gaps = 53/349 (15%)

Query: 9   SLLSLSPDVPVPS---DHGGTESS--PGWGSSGPWSLS--PSDSSPSGVTSRLPGRSTSL 61
           SL S SP  P+ S       T+SS  P    + P SL+  P ++ PS     L   S  L
Sbjct: 494 SLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPL 553

Query: 62  VEGRSCGWVPPPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFSE------- 114
                    PP P   PL     P  +P P +P++ +T P +    L     +       
Sbjct: 554 TTPHL--ETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPL 611

Query: 115 SGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAA 174
           S       +      L  L QA   P     L        + P     H +  P    + 
Sbjct: 612 SPLATPPPQAPPXLALPPL-QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP---FSP 667

Query: 175 PGHPPVLRQSISFSGLPSGRRTSPP---PPGLAGPSL-------SSSSFSPSSSPP---- 220
           P  PPV       +  P     +PP   PP LA P L       +S   SPS++PP    
Sbjct: 668 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727

Query: 221 -------------PPGDLPLSPSAFSAAPGTPLARRDP--TPVCCPSCRRATPISVWGPL 265
                        PP   P+SPSA       PL    P   P   P+    +P++   P 
Sbjct: 728 PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQ 787

Query: 266 G-GLVRTPSVQSLGSDPDEYASSGSSLGGSDSPVFEAGVFAPPQPVAAP 313
               + TP +Q+L S P   AS       S S        A P P A P
Sbjct: 788 APPALATPPLQALPSPP---ASFPGQAPFSPSASLPMSPLATPPPQAPP 833



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 69/288 (23%), Positives = 95/288 (32%), Gaps = 53/288 (18%)

Query: 41   SPSDSSPSGVTSRLPGRSTSLVEGRSCGWVPPPPGFAPLAPRLGPELSPSPTSPTATSTT 100
            SP  S P   ++  P R   L+        P PP   P++P       P P +P A +T 
Sbjct: 740  SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA----KPPPQAPPALATP 795

Query: 101  PSRYKTELCRTFSESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGS 160
            P +       +F   G+  +         L     A   P+    L          P  S
Sbjct: 796  PLQALPSPPASFP--GQAPFSPSAS----LPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 849

Query: 161  RCHFIHNPSEDLAAPGHPPVLRQSISFSG--LPSGRRTSPPPPG-------LAGPSLSSS 211
                       L AP  PP      S SG  L       PPPP        L+GP L+  
Sbjct: 850  ---------PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH 900

Query: 212  SFSPSSSPP----------------PPGDLPLS---PSAFSAAPGTPLARRDPTPVCCPS 252
            S S +S+P                 PP D  L+   P+A+S  P  PLA R       P 
Sbjct: 901  SSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPW 960

Query: 253  CRRATP------ISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGS 294
                 P       +++   G    TP+  +L   P    S G +  G+
Sbjct: 961  PPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA 1008



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 41/127 (32%), Positives = 53/127 (41%), Gaps = 14/127 (11%)

Query: 197 SPPPPGLAGPSLSSSSFSPSSSPP----PPGDLPLSPSAFSAAPGTPLARRDPTPVCCPS 252
           SPP  GL  P LS  +  P  +PP    PP   P SP A  + P +PLA    TP   P 
Sbjct: 600 SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA--SPPLSPLA----TP--SPQ 651

Query: 253 CRRATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGSDSPVFEAG--VFAPPQPV 310
              A  + +         +P VQ+  S P     S S+   S +P   A   +  PP P 
Sbjct: 652 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 711

Query: 311 AAPRRLP 317
           A+P   P
Sbjct: 712 ASPPMSP 718



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 53/174 (30%), Positives = 62/174 (35%), Gaps = 43/174 (24%)

Query: 172 LAAPGHPPVLRQSISFSGLPSGRRTSPPP---PGLAGPSLSSSSFSPSSSP-----PPPG 223
           L  P  PP        + LP      PPP   P LA P L +    P+S P      P  
Sbjct: 766 LQVPPSPP--------ASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 817

Query: 224 DLPLSPSAFS--------------------AAPGTPLARRDPT--PVCCPSCRRATPISV 261
            LP+SP A                      A+P     RR PT  P    S  R T    
Sbjct: 818 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 877

Query: 262 WGPLGGLVRTPSVQSLGSDPDEYASSGSS----LGGSDSPVFEAGVFAPPQPVA 311
            GP     R+PS    G D   ++SS +S    L G DS   E G  A P P A
Sbjct: 878 PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGP-EGGAAASPPPDA 930



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 76/318 (23%), Positives = 111/318 (34%), Gaps = 52/318 (16%)

Query: 18  PVPSDHGGTESSPGWGSS----GPWS-----LSPSDSSPSGVTSRLPGRSTSLVEGR--S 66
           P  +   G  SSPG  S     GP       +S  ++   G  +  P RS      R  +
Sbjct: 105 PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT 164

Query: 67  CGWVP--PPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFSESGRCRYG--A 122
            G  P  P P  A  +   G E+     +P+A    P+    +   + SE         A
Sbjct: 165 SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA 224

Query: 123 KCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPVLR 182
           + + + G G  R A+R                  P  S      +      AP HP   +
Sbjct: 225 RRRPSAGGGLQRPASRSLS-----------SSATPLSSPARSGPSARGTPRAPAHPSQPK 273

Query: 183 QSISFSGLPSGRRTSPPPPGL-AGPSLSSSSFSPSSSPPPPGD--LPLSPSAFSAAP--- 236
                 GL + R     PP   A P+L   S SP ++P P G    P+ P   +A P   
Sbjct: 274 PK----GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPA 329

Query: 237 --------GTPLARRDPTPVCCPSCRR-----ATPISVWGP---LGGLVRTPSVQSLGSD 280
                    TPL    P+P   PS +      ATP S   P      +   PS+Q++   
Sbjct: 330 TLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPI 389

Query: 281 PDEYASSGSSLGGSDSPV 298
              ++ +  SL    SP+
Sbjct: 390 QVPHSLTSPSLQAPPSPL 407



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 27/76 (35%), Positives = 36/76 (47%), Gaps = 13/76 (17%)

Query: 193 GRRTSPPPPGLAGPSLSS--SSFSPSSSPPPPGDLPLSPSAFSAAPGTPLARRDPTPVCC 250
           G  T P     AGP+ S+  SS +P+S PP  G    +P A + +PG         PV  
Sbjct: 66  GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG---------PVSS 116

Query: 251 PSCRRATPISVWGPLG 266
           P   RA+  +  GPLG
Sbjct: 117 PG--RASGTTRPGPLG 130



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 43/160 (26%), Positives = 53/160 (33%), Gaps = 21/160 (13%)

Query: 173 AAPGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAF 232
           +A   PP      S S       T P P     PS       P+S        PLS  A 
Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254

Query: 233 S--AAPGTPLARRDPT------------PVCCPSCRRATPISVWGPLGGL-VRTPSVQSL 277
           S  +A GTP A   P+            P   P  + A P    GPL    + TPS    
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP--ALGPLSSSPLATPSPSGT 312

Query: 278 GS----DPDEYASSGSSLGGSDSPVFEAGVFAPPQPVAAP 313
            +     PD  A+   +      P+      APP P A P
Sbjct: 313 KARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPP 352



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 40/147 (27%), Positives = 59/147 (40%), Gaps = 17/147 (11%)

Query: 168 PSEDLAAPGH--PPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDL 225
           PS  LA P    PP      S   LPS   T   PP  A PS+++    P  +PP    +
Sbjct: 333 PSPPLATPLPLAPPSPSAPPSLQTLPSPPAT---PPSQAPPSMTTP---PMQAPPSLQTI 386

Query: 226 PLSPSAFSAAPGTPLARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEYA 285
           P  P     +  +P  +  P+P+   S +  T  S+  P   L  T S  ++     + +
Sbjct: 387 P--PIQVPHSLTSPSLQAPPSPLALSSLQATT--SLGSPT--LQATHSFLTMSPRQTQAS 440

Query: 286 SSGSSLGGS---DSPVFEAGVFAPPQP 309
            +  S   S   DSP  +A +  P  P
Sbjct: 441 LTSPSRPASTPPDSPPLQAPLSLPASP 467


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 38/131 (29%), Positives = 53/131 (40%), Gaps = 10/131 (7%)

Query: 188 SGLPSGRRTSPPPPGLAGPSLSSSSFSP--SSSPPPPGDLPLSPSAFSAAPGTPLARRDP 245
           S  P     +PP P    P+  SSS  P  +++PP P     +P + SA P T  A   P
Sbjct: 159 SPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAA--PP 216

Query: 246 TPVC---CPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGSDSPVFEAG 302
           TP      P    A P +   P      TP+  S  + P+  A   +    +  P   + 
Sbjct: 217 TPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDP---SS 273

Query: 303 VFAPPQPVAAP 313
             APP+  AAP
Sbjct: 274 ASAPPETTAAP 284



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 32/112 (28%), Positives = 43/112 (38%), Gaps = 3/112 (2%)

Query: 168 PSEDLAAPGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPL 227
           P E  AAP  P    Q+   S  P     +PP P    P+  SSS  P ++  PP     
Sbjct: 185 PPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSAT 244

Query: 228 SPSAFSAAPGTPLARRDPTPVCC---PSCRRATPISVWGPLGGLVRTPSVQS 276
           +P+  S++         PTP      PS   A P +   P      TP+  S
Sbjct: 245 TPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPS 296



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 41/147 (27%), Positives = 56/147 (38%), Gaps = 12/147 (8%)

Query: 168 PSEDLAAPGHPPVLRQSISFSGLPSGRRTSPPPPGL---AGPSLSSSSFSPSSSPPPPGD 224
           P +  AAP  P     +   S  P     +PP P     A PS S+   + ++ P PP  
Sbjct: 162 PQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPAT 221

Query: 225 LPLSPSAFSAAPGTPLARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEY 284
            P  PS+ SA P T  A   PT    PS     P+S   P       P+  +   DP   
Sbjct: 222 TPAPPSS-SAPPETTAA--PPT----PSATTPAPLSSSAPPETTAVPPTPSATTLDPSSA 274

Query: 285 ASSGSSLGGSDSPVFEAGVFAPPQPVA 311
           ++   +     +P   A   APP   A
Sbjct: 275 SAPPETTAAPPTP--SATTPAPPSSPA 299



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 31/110 (28%), Positives = 43/110 (39%), Gaps = 20/110 (18%)

Query: 168 PSEDLAAPGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSP------------ 215
           P E  AAP  PP    +   S  P     +PP P    P+  SSS  P            
Sbjct: 208 PPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSAT 267

Query: 216 ------SSSPPPPGDLPLSPSAFSAAPGTPLARRDPT--PVCCPSCRRAT 257
                 +S+PP     P +PSA + AP +  A ++ T  P+  P+    T
Sbjct: 268 TLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTT 317



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 14/103 (13%)

Query: 9   SLLSLSP-DVPVPSDHGGTESSPGWGSSGPWSLSPSDSSP---------SGVTSRLPGRS 58
           S+ +L+P + P P D      +P   +  P    PS S+P            T++ P  S
Sbjct: 150 SVATLAPVNSPAPQDTTAAPPTPSATTPAP----PSSSAPPETTAAPPTPSATTQAPPSS 205

Query: 59  TSLVEGRSCGWVPPPPGFAPLAPRLGPELSPSPTSPTATSTTP 101
           ++  E  +    PP    AP +    PE + +P +P+AT+  P
Sbjct: 206 SAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAP 248



 Score = 32.7 bits (73), Expect = 0.45
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 14/90 (15%)

Query: 15  PDVPVPSDHGGTESSPGWGSSGPWSLSPSDSSPSGVTSRLPGRSTSLVEGRSCGWVPPPP 74
           P  P  +    + S+P   ++ P   +PS ++P+ ++S  P  +T+         VPP P
Sbjct: 216 PTPPATTPAPPSSSAPPETTAAP--PTPSATTPAPLSSSAPPETTA---------VPPTP 264

Query: 75  GFAPLAPRLG---PELSPSPTSPTATSTTP 101
               L P      PE + +P +P+AT+  P
Sbjct: 265 SATTLDPSSASAPPETTAAPPTPSATTPAP 294



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 32/121 (26%), Positives = 49/121 (40%), Gaps = 9/121 (7%)

Query: 196 TSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPLARRDPTPVC---CPS 252
           TS     LA  +  +   + ++ P P    P  PS+ SA P T  A   PTP      P 
Sbjct: 147 TSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSS-SAPPETTAA--PPTPSATTQAPP 203

Query: 253 CRRATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGSDSPVFEAGVFAPPQPVAA 312
              A P +   P      TP+  S  + P+  A+  +    + +P+  +   APP+  A 
Sbjct: 204 SSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSS---APPETTAV 260

Query: 313 P 313
           P
Sbjct: 261 P 261



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 5/85 (5%)

Query: 18  PVPSDHGGTESSPGWGSSGPWSLSPSDSSPSGVTSRLPGRSTSLVEGRSCGWVPPPPGFA 77
           P PS    T  +P   S+ P + +   + P+  T+  P  S++  E  +    P     A
Sbjct: 193 PTPS---ATTQAPPSSSAPPETTAAPPTPPA--TTPAPPSSSAPPETTAAPPTPSATTPA 247

Query: 78  PLAPRLGPELSPSPTSPTATSTTPS 102
           PL+    PE +  P +P+AT+  PS
Sbjct: 248 PLSSSAPPETTAVPPTPSATTLDPS 272


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 38/131 (29%), Positives = 53/131 (40%), Gaps = 10/131 (7%)

Query: 188 SGLPSGRRTSPPPPGLAGPSLSSSSFSP--SSSPPPPGDLPLSPSAFSAAPGTPLARRDP 245
           S  P     +PP P    P+  SSS  P  +++PP P     +P + SA P T  A   P
Sbjct: 159 SPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAA--PP 216

Query: 246 TPVC---CPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGSDSPVFEAG 302
           TP      P    A P +   P      TP+  S  + P+  A   +    +  P   + 
Sbjct: 217 TPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDP---SS 273

Query: 303 VFAPPQPVAAP 313
             APP+  AAP
Sbjct: 274 ASAPPETTAAP 284



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 32/112 (28%), Positives = 43/112 (38%), Gaps = 3/112 (2%)

Query: 168 PSEDLAAPGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPL 227
           P E  AAP  P    Q+   S  P     +PP P    P+  SSS  P ++  PP     
Sbjct: 185 PPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSAT 244

Query: 228 SPSAFSAAPGTPLARRDPTPVCC---PSCRRATPISVWGPLGGLVRTPSVQS 276
           +P+  S++         PTP      PS   A P +   P      TP+  S
Sbjct: 245 TPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPS 296



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 41/147 (27%), Positives = 56/147 (38%), Gaps = 12/147 (8%)

Query: 168 PSEDLAAPGHPPVLRQSISFSGLPSGRRTSPPPPGL---AGPSLSSSSFSPSSSPPPPGD 224
           P +  AAP  P     +   S  P     +PP P     A PS S+   + ++ P PP  
Sbjct: 162 PQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPAT 221

Query: 225 LPLSPSAFSAAPGTPLARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEY 284
            P  PS+ SA P T  A   PT    PS     P+S   P       P+  +   DP   
Sbjct: 222 TPAPPSS-SAPPETTAA--PPT----PSATTPAPLSSSAPPETTAVPPTPSATTLDPSSA 274

Query: 285 ASSGSSLGGSDSPVFEAGVFAPPQPVA 311
           ++   +     +P   A   APP   A
Sbjct: 275 SAPPETTAAPPTP--SATTPAPPSSPA 299



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 31/110 (28%), Positives = 43/110 (39%), Gaps = 20/110 (18%)

Query: 168 PSEDLAAPGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSP------------ 215
           P E  AAP  PP    +   S  P     +PP P    P+  SSS  P            
Sbjct: 208 PPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSAT 267

Query: 216 ------SSSPPPPGDLPLSPSAFSAAPGTPLARRDPT--PVCCPSCRRAT 257
                 +S+PP     P +PSA + AP +  A ++ T  P+  P+    T
Sbjct: 268 TLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTT 317



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 14/103 (13%)

Query: 9   SLLSLSP-DVPVPSDHGGTESSPGWGSSGPWSLSPSDSSP---------SGVTSRLPGRS 58
           S+ +L+P + P P D      +P   +  P    PS S+P            T++ P  S
Sbjct: 150 SVATLAPVNSPAPQDTTAAPPTPSATTPAP----PSSSAPPETTAAPPTPSATTQAPPSS 205

Query: 59  TSLVEGRSCGWVPPPPGFAPLAPRLGPELSPSPTSPTATSTTP 101
           ++  E  +    PP    AP +    PE + +P +P+AT+  P
Sbjct: 206 SAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAP 248



 Score = 32.7 bits (73), Expect = 0.45
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 14/90 (15%)

Query: 15  PDVPVPSDHGGTESSPGWGSSGPWSLSPSDSSPSGVTSRLPGRSTSLVEGRSCGWVPPPP 74
           P  P  +    + S+P   ++ P   +PS ++P+ ++S  P  +T+         VPP P
Sbjct: 216 PTPPATTPAPPSSSAPPETTAAP--PTPSATTPAPLSSSAPPETTA---------VPPTP 264

Query: 75  GFAPLAPRLG---PELSPSPTSPTATSTTP 101
               L P      PE + +P +P+AT+  P
Sbjct: 265 SATTLDPSSASAPPETTAAPPTPSATTPAP 294



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 32/121 (26%), Positives = 49/121 (40%), Gaps = 9/121 (7%)

Query: 196 TSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSAAPGTPLARRDPTPVC---CPS 252
           TS     LA  +  +   + ++ P P    P  PS+ SA P T  A   PTP      P 
Sbjct: 147 TSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSS-SAPPETTAA--PPTPSATTQAPP 203

Query: 253 CRRATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGSDSPVFEAGVFAPPQPVAA 312
              A P +   P      TP+  S  + P+  A+  +    + +P+  +   APP+  A 
Sbjct: 204 SSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSS---APPETTAV 260

Query: 313 P 313
           P
Sbjct: 261 P 261



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 5/85 (5%)

Query: 18  PVPSDHGGTESSPGWGSSGPWSLSPSDSSPSGVTSRLPGRSTSLVEGRSCGWVPPPPGFA 77
           P PS    T  +P   S+ P + +   + P+  T+  P  S++  E  +    P     A
Sbjct: 193 PTPS---ATTQAPPSSSAPPETTAAPPTPPA--TTPAPPSSSAPPETTAAPPTPSATTPA 247

Query: 78  PLAPRLGPELSPSPTSPTATSTTPS 102
           PL+    PE +  P +P+AT+  PS
Sbjct: 248 PLSSSAPPETTAVPPTPSATTLDPS 272


>gi|73695473 roquin [Homo sapiens]
          Length = 1133

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 54/223 (24%), Positives = 77/223 (34%), Gaps = 21/223 (9%)

Query: 102 SRYKTELCRTFSESGRCRYGAKCQFAHGLGEL---RQANRHPKYKTELCHKFYLQGRCPY 158
           S+YKT +CR   + G C  GA C FAH   EL   R+ N+    +  L            
Sbjct: 412 SKYKTYMCRDMKQRGGCPRGASCTFAHSQEELEKFRKMNKRLVPRRPLSASLGQLNEVGL 471

Query: 159 GSRCHFIHNPSEDLAAPGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSS------- 211
            S        + DL +   PP L   I    + +G   +   P    PS  SS       
Sbjct: 472 PSAAILPDEGAVDLPS-RKPPALPNGI----VSTGNTVTQLIPRGTDPSYDSSLKPGKID 526

Query: 212 SFSPSSSPPPPGDLPLSPSAFSAAPGTPLARRDPTPVCCPSCRRATPISVWGPLGGLVRT 271
             S S+   PP  L   P + SA P  P +     P   P      P+ V  PL  + R 
Sbjct: 527 HLSSSAPGSPPDLLESVPKSISALPVNPHSIPPRGPADLP------PMPVTKPLQMVPRG 580

Query: 272 PSVQSLGSDPDEYASSGSSLGGSDSPVFEAGVFAPPQPVAAPR 314
             +         Y     +    +   ++ G++  P P    R
Sbjct: 581 SQLYPAQQTDVYYQDPRGAAPPFEPAPYQQGMYYTPPPQCVSR 623



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 38/131 (29%), Positives = 51/131 (38%), Gaps = 25/131 (19%)

Query: 134 RQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPS--EDLAAPGHPPVLRQSISFS--- 188
           +Q  +H KYKT +C     +G CP G+ C F H+    E         V R+ +S S   
Sbjct: 406 QQPPQHSKYKTYMCRDMKQRGGCPRGASCTFAHSQEELEKFRKMNKRLVPRRPLSASLGQ 465

Query: 189 ----GLPSGR---------RTSPPPPGLAGPSLSSSSFSPSSSP---PPPGDLPLSPSAF 232
               GLPS             S  PP L    +S+ +      P    P  D  L P   
Sbjct: 466 LNEVGLPSAAILPDEGAVDLPSRKPPALPNGIVSTGNTVTQLIPRGTDPSYDSSLKPGKI 525

Query: 233 ----SAAPGTP 239
               S+APG+P
Sbjct: 526 DHLSSSAPGSP 536


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.133    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,483,277
Number of Sequences: 37866
Number of extensions: 1407171
Number of successful extensions: 15910
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 314
Number of HSP's successfully gapped in prelim test: 1067
Number of HSP's that attempted gapping in prelim test: 9385
Number of HSP's gapped (non-prelim): 6070
length of query: 326
length of database: 18,247,518
effective HSP length: 103
effective length of query: 223
effective length of database: 14,347,320
effective search space: 3199452360
effective search space used: 3199452360
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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