Guide to the Human Genome
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Search of human proteins with 4507923

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507923 WNT1 inducible signaling pathway protein 2 precursor
[Homo sapiens]
         (250 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507923 WNT1 inducible signaling pathway protein 2 precursor ...   560   e-160
gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens]      219   2e-57
gi|4503123 connective tissue growth factor [Homo sapiens]             216   1e-56
gi|31542331 cysteine-rich, angiogenic inducer, 61 [Homo sapiens]      198   4e-51
gi|4507921 WNT1 inducible signaling pathway protein 1 isoform 1 ...   191   4e-49
gi|38202241 WNT1 inducible signaling pathway protein 3 isoform 3...   132   2e-31
gi|4507925 WNT1 inducible signaling pathway protein 3 isoform 1 ...   132   2e-31
gi|18491000 WNT1 inducible signaling pathway protein 1 isoform 2...    82   3e-16
gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]    56   3e-08
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]    51   8e-07
gi|56090548 insulin-like growth factor binding protein-like 1 [H...    50   2e-06
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]               47   2e-05
gi|33598931 scavenger receptor class F, member 1 isoform 3 precu...    46   3e-05
gi|33598929 scavenger receptor class F, member 1 isoform 1 precu...    46   3e-05
gi|24308541 HtrA serine peptidase 4 precursor [Homo sapiens]           46   3e-05
gi|22129776 HtrA serine peptidase 3 [Homo sapiens]                     46   3e-05
gi|5901946 endothelial cell-specific molecule 1 isoform a precur...    45   8e-05
gi|208022668 endothelial cell-specific molecule 1 isoform b prec...    44   1e-04
gi|55925576 insulin-like growth factor binding protein 2, 36kDa ...    44   1e-04
gi|40317628 thrombospondin 2 precursor [Homo sapiens]                  44   1e-04
gi|40353769 chordin-like 2 [Homo sapiens]                              43   2e-04
gi|4504619 insulin-like growth factor binding protein 7 [Homo sa...    43   2e-04
gi|134031945 SCO-spondin [Homo sapiens]                                43   2e-04
gi|33624896 ADAM metallopeptidase with thrombospondin type 1 mot...    41   0.001
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s...    41   0.001
gi|161019170 mucin 5AC [Homo sapiens]                                  40   0.001
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       40   0.001
gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens]            40   0.002
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       40   0.002
gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens]             39   0.003

>gi|4507923 WNT1 inducible signaling pathway protein 2 precursor
           [Homo sapiens]
          Length = 250

 Score =  560 bits (1444), Expect = e-160
 Identities = 250/250 (100%), Positives = 250/250 (100%)

Query: 1   MRGTPKTHLLAFSLLCLLSKVRTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRL 60
           MRGTPKTHLLAFSLLCLLSKVRTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRL
Sbjct: 1   MRGTPKTHLLAFSLLCLLSKVRTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRL 60

Query: 61  GEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIR 120
           GEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIR
Sbjct: 61  GEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIR 120

Query: 121 CRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQ 180
           CRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQ
Sbjct: 121 CRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQ 180

Query: 181 FSGLVSSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPCPPS 240
           FSGLVSSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPCPPS
Sbjct: 181 FSGLVSSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPCPPS 240

Query: 241 RGRSPQNSAF 250
           RGRSPQNSAF
Sbjct: 241 RGRSPQNSAF 250


>gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens]
          Length = 357

 Score =  219 bits (557), Expect = 2e-57
 Identities = 110/233 (47%), Positives = 134/233 (57%), Gaps = 6/233 (2%)

Query: 10  LAFSLLCLLSKVR-TQLCPTPCT--CPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQ 66
           L F LL LL +V  TQ CP  C   CP  PP C  GV  VLDGC CC VCAR+ GE C  
Sbjct: 18  LTFLLLHLLGQVAATQRCPPQCPGRCPATPPTCAPGVRAVLDGCSCCLVCARQRGESCSD 77

Query: 67  LHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDG 126
           L  CD S GL C   A P  +  +C   E D+ C  +G +YR GE FQP C  +C C DG
Sbjct: 78  LEPCDESSGLYCDRSADPSNQTGICTAVEGDN-CVFDGVIYRSGEKFQPSCKFQCTCRDG 136

Query: 127 GFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCG--QGGGLGTQPLPAQGPQFSGL 184
              CVP C  DV LP  +CP PR+VEV G+CC +W+CG  +   LG   L A  P+ +  
Sbjct: 137 QIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEEDSLGGLTLAAYRPEATLG 196

Query: 185 VSSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPC 237
           V      V C E +T W  CS +CG+G +TRV+N+NR C +  Q RLC+ RPC
Sbjct: 197 VEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQTRLCMVRPC 249


>gi|4503123 connective tissue growth factor [Homo sapiens]
          Length = 349

 Score =  216 bits (550), Expect = 1e-56
 Identities = 111/233 (47%), Positives = 137/233 (58%), Gaps = 15/233 (6%)

Query: 14  LLCLLSKVRT-QLCPTPCTCP-WPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCD 71
           LL L S+    Q C  PC CP  P PRCP GV LVLDGCGCCRVCA++LGE C +   CD
Sbjct: 16  LLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCD 75

Query: 72  ASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCV 131
             +GL C  G+    +  +C  A+D + C   G +YR GE+FQ  C  +C C DG   C+
Sbjct: 76  PHKGLFCDFGSPANRKIGVCT-AKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCM 134

Query: 132 PLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQFSG--LVSSLP 189
           PLCS DVRLPS DCP PRRV++ GKCC EWVC +      +     GP  +   L  +  
Sbjct: 135 PLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDE-----PKDQTVVGPALAAYRLEDTFG 189

Query: 190 PG-----VPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPC 237
           P        C   +T W  CS TCG+G++TRV+N N  CRLE Q RLC+ RPC
Sbjct: 190 PDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRPC 242


>gi|31542331 cysteine-rich, angiogenic inducer, 61 [Homo sapiens]
          Length = 381

 Score =  198 bits (503), Expect = 4e-51
 Identities = 96/256 (37%), Positives = 132/256 (51%), Gaps = 37/256 (14%)

Query: 18  LSKVRTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLV 77
           L+++    CP  C CP   P+C  GV LV DGCGCC+VCA++L E C +   CD ++GL 
Sbjct: 18  LTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLE 77

Query: 78  CQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCVPLCSED 137
           C  GA       +C    +   CE N R+Y+ GE+FQP+C  +C C DG   C+PLC ++
Sbjct: 78  CNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQE 137

Query: 138 VRLPSWDCPHPRRVEVLGKCCPEWVCGQ-------------------------------- 165
           + LP+  CP+PR V+V G+CC EWVC +                                
Sbjct: 138 LSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNE 197

Query: 166 ----GGGLGTQPLPAQGPQFSGLVSSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNR 221
               G G   + LP  G +   L + L  G  C   +T+W  CS TCG G++TRV+N N 
Sbjct: 198 LIAVGKGSSLKRLPVFGMEPRILYNPL-QGQKCIVQTTSWSQCSKTCGTGISTRVTNDNP 256

Query: 222 FCRLETQRRLCLSRPC 237
            CRL  + R+C  RPC
Sbjct: 257 ECRLVKETRICEVRPC 272


>gi|4507921 WNT1 inducible signaling pathway protein 1 isoform 1
           precursor [Homo sapiens]
          Length = 367

 Score =  191 bits (486), Expect = 4e-49
 Identities = 92/217 (42%), Positives = 122/217 (56%), Gaps = 3/217 (1%)

Query: 22  RTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVCQPG 81
           R Q C  PC CP  PPRCPLGV L+ DGC CC++CA++LG+ C +  +CD  +GL C   
Sbjct: 45  RPQFCKWPCECPPSPPRCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYCD-Y 103

Query: 82  AGPGGRGALCLLAE-DDSSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCVPLCSEDVRL 140
           +G   R A+ + A+     C ++G  Y  G++FQP+C   C C DG   C PLC   VR 
Sbjct: 104 SGDRPRYAIGVCAQVVGVGCVLDGVRYNNGQSFQPNCKYNCTCIDGAVGCTPLCLR-VRP 162

Query: 141 PSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQFSGLVSSLPPGVPCPEWSTA 200
           P   CPHPRRV + G CC +WVC        +  P     F  +         C  +++ 
Sbjct: 163 PRLWCPHPRRVSIPGHCCEQWVCEDDAKRPRKTAPRDTGAFDAVGEVEAWHRNCIAYTSP 222

Query: 201 WGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPC 237
           W PCST+CGLG++TR+SN N  C  E + RLC  RPC
Sbjct: 223 WSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPC 259


>gi|38202241 WNT1 inducible signaling pathway protein 3 isoform 3
           [Homo sapiens]
          Length = 372

 Score =  132 bits (333), Expect = 2e-31
 Identities = 78/227 (34%), Positives = 107/227 (47%), Gaps = 29/227 (12%)

Query: 22  RTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVCQPG 81
           R Q C  PC CP   PRCP GV LV DGCGCC++CA++ GE C++  +CD  +GL C   
Sbjct: 62  RKQFCHWPCKCPQQKPRCPPGVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYS 121

Query: 82  AG-PGGRGALC--LLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCVPLCSEDV 138
              P     +C  L+A     CE N   Y  G+ FQP+    C C  G   C PL     
Sbjct: 122 VDRPRYETGVCAYLVA---VGCEFNQVHYHNGQVFQPNPLFSCLCVSGAIGCTPLF---- 174

Query: 139 RLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQFSGLVSSLPP--GVP--- 193
            +P          ++ G  C     G+        L     Q S    ++P    +P   
Sbjct: 175 -IP----------KLAGSHCSGAKGGKKSDQSNCSLEPLLQQLSTSYKTMPAYRNLPLIW 223

Query: 194 ---CPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPC 237
              C   +T W PCS TCG+G++ RV+N+N  C +  ++RLC  +PC
Sbjct: 224 KKKCLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEKRLCYIQPC 270


>gi|4507925 WNT1 inducible signaling pathway protein 3 isoform 1
           [Homo sapiens]
          Length = 354

 Score =  132 bits (333), Expect = 2e-31
 Identities = 78/227 (34%), Positives = 107/227 (47%), Gaps = 29/227 (12%)

Query: 22  RTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVCQPG 81
           R Q C  PC CP   PRCP GV LV DGCGCC++CA++ GE C++  +CD  +GL C   
Sbjct: 44  RKQFCHWPCKCPQQKPRCPPGVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYS 103

Query: 82  AG-PGGRGALC--LLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCVPLCSEDV 138
              P     +C  L+A     CE N   Y  G+ FQP+    C C  G   C PL     
Sbjct: 104 VDRPRYETGVCAYLVA---VGCEFNQVHYHNGQVFQPNPLFSCLCVSGAIGCTPLF---- 156

Query: 139 RLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQFSGLVSSLPP--GVP--- 193
            +P          ++ G  C     G+        L     Q S    ++P    +P   
Sbjct: 157 -IP----------KLAGSHCSGAKGGKKSDQSNCSLEPLLQQLSTSYKTMPAYRNLPLIW 205

Query: 194 ---CPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPC 237
              C   +T W PCS TCG+G++ RV+N+N  C +  ++RLC  +PC
Sbjct: 206 KKKCLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEKRLCYIQPC 252


>gi|18491000 WNT1 inducible signaling pathway protein 1 isoform 2
           precursor [Homo sapiens]
          Length = 280

 Score = 82.4 bits (202), Expect = 3e-16
 Identities = 31/57 (54%), Positives = 40/57 (70%)

Query: 22  RTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVC 78
           R Q C  PC CP  PPRCPLGV L+ DGC CC++CA++LG+ C +  +CD  +GL C
Sbjct: 45  RPQFCKWPCECPPSPPRCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYC 101



 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 23/44 (52%), Positives = 31/44 (70%)

Query: 194 CPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPC 237
           C  +++ W PCST+CGLG++TR+SN N  C  E + RLC  RPC
Sbjct: 129 CIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPC 172


>gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]
          Length = 814

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 51/154 (33%), Positives = 56/154 (36%), Gaps = 33/154 (21%)

Query: 71  DASQGLVCQPGA---GPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDGG 127
           DA    VCQ GA   GP      C        C  NG+ Y  GETF P     CRC +G 
Sbjct: 112 DACTACVCQDGAAHCGPQAHLPHC------RGCSQNGQTYGNGETFSPDACTTCRCLEGT 165

Query: 128 FTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWV--CGQGGGL---GTQPLPAQGP--Q 180
            TC          P   CP P      G CCP     C   G L   G   L +  P  Q
Sbjct: 166 ITC-----NQKPCPRGPCPEP------GACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQ 214

Query: 181 FSGLVSSLP------PGVPCPEWSTAWGPCSTTC 208
            + L S +       P  PCPE     G C  TC
Sbjct: 215 CTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPTC 248



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 59/195 (30%), Positives = 69/195 (35%), Gaps = 54/195 (27%)

Query: 26  CPTPCTCPWPP-------PRCP---LGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQG 75
           CP P TC  P        PRCP   L   + +DG             P D    C   +G
Sbjct: 520 CP-PTTCARPQSGPGQCCPRCPDCILEEEVFVDG--------ESFSHPRDPCQECRCQEG 570

Query: 76  LV-CQPGAGPGGR------GALCLLAEDDSSCEVNGRLYREGETFQPH----CSIRCRCE 124
              CQP   P         G  C    D S C   G+ Y  G  F PH    C + CRC 
Sbjct: 571 HAHCQPRPCPRAPCAHPLPGTCC--PNDCSGCAFGGKEYPSGADF-PHPSDPCRL-CRCL 626

Query: 125 DGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQFSGL 184
            G   C  L    V LP   CP P  V + G+CCP+            P PA  P+    
Sbjct: 627 SGNVQC--LARRCVPLP---CPEP--VLLPGECCPQ--------CPAAPAPAGCPRPGAA 671

Query: 185 VSS-----LPPGVPC 194
            +       PPG PC
Sbjct: 672 HARHQEYFSPPGDPC 686



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 49/170 (28%), Positives = 63/170 (37%), Gaps = 49/170 (28%)

Query: 16  CLLSKVRTQL--CPTPCTCPWP---PPRCPLGVPLVLDGCGCCRVCA---------RRLG 61
           CL S+VR     CP P  CP P   P  C          C  C+ C          +   
Sbjct: 217 CLRSRVRCMALKCP-PSPCPEPVLRPGHC----------CPTCQGCTEGGSHWEHGQEWT 265

Query: 62  EPCDQLHVCDASQGLV----------CQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGE 111
            P D   +C   +G +          C   A P   G  C + +    C +NGR +R GE
Sbjct: 266 TPGDPCRICRCLEGHIQCRQRECASLCPYPARPLP-GTCCPVCD---GCFLNGREHRSGE 321

Query: 112 TFQPH--CSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCP 159
                  CS  CRC +G   C PL       P   C HP ++   G+CCP
Sbjct: 322 PVGSGDPCS-HCRCANGSVQCEPL-----PCPPVPCRHPGKIP--GQCCP 363



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 66/258 (25%), Positives = 87/258 (33%), Gaps = 68/258 (26%)

Query: 29  PCTCPWPPPRCPLGVP----LVLDGC------------------GCCRVCARRLGEPCDQ 66
           P  CP  P R P  +P     V DGC                  G C  C+ + GE   +
Sbjct: 343 PLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCE 402

Query: 67  LHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPH---CSIRCRC 123
              C  +      P A P     LC       +CE++G  + EG  ++P    C+  C C
Sbjct: 403 EQECPVT------PCALPASGRQLC------PACELDGEEFAEGVQWEPDGRPCTA-CVC 449

Query: 124 EDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPE----------WVCGQGGGLGTQP 173
           +DG    VP C   V  P   C HP +    G CCP           +  GQ       P
Sbjct: 450 QDG----VPKCGA-VLCPPAPCQHPTQPP--GACCPSCDSCTYHSQVYANGQNFTDADSP 502

Query: 174 LPAQGPQFSGLVSSLP--PGVPCPEWSTAWGPCSTTCG---LGMATRVSNQN-------- 220
             A   Q   +  SL   P   C    +  G C   C    L     V  ++        
Sbjct: 503 CHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPC 562

Query: 221 RFCRLETQRRLCLSRPCP 238
           + CR +     C  RPCP
Sbjct: 563 QECRCQEGHAHCQPRPCP 580



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 58/242 (23%), Positives = 73/242 (30%), Gaps = 89/242 (36%)

Query: 25  LCP-TPCTCPWPPPR--CPLGVPLVLDGCGCCRVCARRLGE---------PCDQLHVCDA 72
           LCP  PC  P  PP   CP         C  C   ++             PC   H C  
Sbjct: 460 LCPPAPCQHPTQPPGACCP--------SCDSCTYHSQVYANGQNFTDADSPC---HACHC 508

Query: 73  SQGLV------------CQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETF---QPHC 117
             G V             +P +GPG     C        C +   ++ +GE+F   +  C
Sbjct: 509 QDGTVTCSLVDCPPTTCARPQSGPGQCCPRC------PDCILEEEVFVDGESFSHPRDPC 562

Query: 118 SIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQ 177
              CRC++G   C P        P   C HP    + G CCP    G   G    P  A 
Sbjct: 563 Q-ECRCQEGHAHCQPR-----PCPRAPCAHP----LPGTCCPNDCSGCAFGGKEYPSGAD 612

Query: 178 GPQFSGLVSSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPC 237
            P          P  PC                          R CR  +    CL+R C
Sbjct: 613 FPH---------PSDPC--------------------------RLCRCLSGNVQCLARRC 637

Query: 238 PP 239
            P
Sbjct: 638 VP 639



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 45/150 (30%), Positives = 56/150 (37%), Gaps = 30/150 (20%)

Query: 24  QLCP-TPCTCPWPP----PRCPL-------GVPLVLDGCGCCRVCARRLGEPCDQLHVCD 71
           Q CP TPC  P       P C L       GV    DG  C   C  + G P     +C 
Sbjct: 404 QECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCT-ACVCQDGVPKCGAVLCP 462

Query: 72  ASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSI--RCRCEDGGFT 129
            +    CQ    P G  A C   +   SC  + ++Y  G+ F    S    C C+DG  T
Sbjct: 463 PAP---CQHPTQPPG--ACCPSCD---SCTYHSQVYANGQNFTDADSPCHACHCQDGTVT 514

Query: 130 CVPLCSEDVRLPSWDCPHPRRVEVLGKCCP 159
           C       V  P   C  P+     G+CCP
Sbjct: 515 C-----SLVDCPPTTCARPQSGP--GQCCP 537



 Score = 28.1 bits (61), Expect = 7.5
 Identities = 25/75 (33%), Positives = 28/75 (37%), Gaps = 12/75 (16%)

Query: 15  LCLLSKVRTQLCP---TPCTCPWPPPRCPLGVPLVLDGC---GCCRVCARRLGEPCDQLH 68
           LCL   V  Q  P    PC  P   P CP       DGC   G       R   P    H
Sbjct: 690 LCLDGSVSCQRLPCPPAPCAHPRQGPCCP-----SCDGCLYQGKEFASGERFPSPTAACH 744

Query: 69  VCDASQGLV-CQPGA 82
           +C   +G V C+P A
Sbjct: 745 LCLCWEGSVSCEPKA 759


>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
          Length = 1503

 Score = 51.2 bits (121), Expect = 8e-07
 Identities = 39/101 (38%), Positives = 42/101 (41%), Gaps = 19/101 (18%)

Query: 71  DASQGLVCQPGA---GPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDGG 127
           DA    VCQ GA   GP      C        C  NG+ Y  GETF P     CRC  G 
Sbjct: 112 DACTACVCQDGAAHCGPQAHLPHC------RGCSQNGQTYGNGETFSPDACTTCRCLTGA 165

Query: 128 FTCV-PLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGG 167
             C  P CSE   L S  C  P      G+CCP   C +GG
Sbjct: 166 VQCQGPSCSELNCLES--CTPP------GECCP-ICCTEGG 197



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 62/242 (25%), Positives = 78/242 (32%), Gaps = 67/242 (27%)

Query: 15  LCLLSKVRTQLCP---TPCTCPWPPPRCPLGVPLVLDGC---GCCRVCARRLGEPCDQLH 68
           LCL   V  Q  P    PC  P   P CP       DGC   G       R   P    H
Sbjct: 629 LCLDGSVSCQRLPCPPAPCAHPRQGPCCPS-----CDGCLYQGKEFASGERFPSPTAACH 683

Query: 69  VCDASQGLV------CQPGAGP-GGRGALCLLAEDDSSCEVNGRLYREGETF---QPHCS 118
           +C   +G V      C P   P   RG  C    D   CE  G  Y   + F   +  C+
Sbjct: 684 LCLCWEGSVSCEPKACAPALCPFPARGDCC---PDCDGCEYLGESYLSNQEFPDPREPCN 740

Query: 119 IRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQG 178
           + C C  G  TC     E        C HP  +   G CCP                 QG
Sbjct: 741 L-CTCLGGFVTCGRRPCEPP-----GCSHP--LIPSGHCCPT---------------CQG 777

Query: 179 PQFSGLVSSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPCP 238
            ++ G+ ++    +P         P   TC L            C  +     C  +PCP
Sbjct: 778 CRYHGVTTASGETLP--------DPLDPTCSL------------CTCQEGSMRCQKKPCP 817

Query: 239 PS 240
           P+
Sbjct: 818 PA 819



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 59/195 (30%), Positives = 69/195 (35%), Gaps = 57/195 (29%)

Query: 26  CPTPCTCPWPP-------PRCP---LGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQG 75
           CP P TC  P        PRCP   L   + +DG             P D    C   +G
Sbjct: 462 CP-PTTCARPQSGPGQCCPRCPDCILEEEVFVDG--------ESFSHPRDPCQECRCQEG 512

Query: 76  LV-CQPGAGPGGR------GALCLLAEDDSSCEVNGRLYREGETFQPH----CSIRCRCE 124
              CQP   P         G  C    D S C   G+ Y  G  F PH    C + CRC 
Sbjct: 513 HAHCQPRPCPRAPCAHPLPGTCC--PNDCSGCAFGGKEYPSGADF-PHPSDPCRL-CRCL 568

Query: 125 DGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQFSGL 184
            G   C  L    V LP   CP P  V + G+CCP+            P PA  P+    
Sbjct: 569 SGNVQC--LARRCVPLP---CPEP--VLLPGECCPQC-----------PAPAGCPRPGAA 610

Query: 185 VSS-----LPPGVPC 194
            +       PPG PC
Sbjct: 611 HARHQEYFSPPGDPC 625



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 66/258 (25%), Positives = 87/258 (33%), Gaps = 68/258 (26%)

Query: 29  PCTCPWPPPRCPLGVP----LVLDGC------------------GCCRVCARRLGEPCDQ 66
           P  CP  P R P  +P     V DGC                  G C  C+ + GE   +
Sbjct: 285 PLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCE 344

Query: 67  LHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPH---CSIRCRC 123
              C  +      P A P     LC       +CE++G  + EG  ++P    C+  C C
Sbjct: 345 EQECPVT------PCALPASGRQLC------PACELDGEEFAEGVQWEPDGRPCTA-CVC 391

Query: 124 EDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPE----------WVCGQGGGLGTQP 173
           +DG    VP C   V  P   C HP +    G CCP           +  GQ       P
Sbjct: 392 QDG----VPKCGA-VLCPPAPCQHPTQPP--GACCPSCDSCTYHSQVYANGQNFTDADSP 444

Query: 174 LPAQGPQFSGLVSSLP--PGVPCPEWSTAWGPCSTTCG---LGMATRVSNQN-------- 220
             A   Q   +  SL   P   C    +  G C   C    L     V  ++        
Sbjct: 445 CHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPC 504

Query: 221 RFCRLETQRRLCLSRPCP 238
           + CR +     C  RPCP
Sbjct: 505 QECRCQEGHAHCQPRPCP 522



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 37/130 (28%), Positives = 49/130 (37%), Gaps = 34/130 (26%)

Query: 52  CCRVCARRLGE----------PCDQLHVCDASQGLV----------CQPGAGPGGRGALC 91
           CC +C    G           P D   +C   +G +          C   A P   G  C
Sbjct: 188 CCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLP-GTCC 246

Query: 92  LLAEDDSSCEVNGRLYREGETFQPH--CSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPR 149
            + +    C +NGR +R GE       CS  CRC +G   C PL       P   C HP 
Sbjct: 247 PVCD---GCFLNGREHRSGEPVGSGDPCS-HCRCANGSVQCEPL-----PCPPVPCRHPG 297

Query: 150 RVEVLGKCCP 159
           ++   G+CCP
Sbjct: 298 KIP--GQCCP 305



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 58/242 (23%), Positives = 73/242 (30%), Gaps = 89/242 (36%)

Query: 25  LCP-TPCTCPWPPPR--CPLGVPLVLDGCGCCRVCARRLGE---------PCDQLHVCDA 72
           LCP  PC  P  PP   CP         C  C   ++             PC   H C  
Sbjct: 402 LCPPAPCQHPTQPPGACCP--------SCDSCTYHSQVYANGQNFTDADSPC---HACHC 450

Query: 73  SQGLV------------CQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETF---QPHC 117
             G V             +P +GPG     C        C +   ++ +GE+F   +  C
Sbjct: 451 QDGTVTCSLVDCPPTTCARPQSGPGQCCPRC------PDCILEEEVFVDGESFSHPRDPC 504

Query: 118 SIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQ 177
              CRC++G   C P        P   C HP    + G CCP    G   G    P  A 
Sbjct: 505 Q-ECRCQEGHAHCQPR-----PCPRAPCAHP----LPGTCCPNDCSGCAFGGKEYPSGAD 554

Query: 178 GPQFSGLVSSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPC 237
            P          P  PC                          R CR  +    CL+R C
Sbjct: 555 FPH---------PSDPC--------------------------RLCRCLSGNVQCLARRC 579

Query: 238 PP 239
            P
Sbjct: 580 VP 581



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 45/160 (28%), Positives = 58/160 (36%), Gaps = 40/160 (25%)

Query: 30  CTC----------PWPPPRCPLGVPLVLDG--CGCCRVC---------ARRLGEPCDQL- 67
           CTC          P  PP C    PL+  G  C  C+ C            L +P D   
Sbjct: 742 CTCLGGFVTCGRRPCEPPGC--SHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTC 799

Query: 68  HVCDASQGLV------CQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQ-PHCSIR 120
            +C   +G +      C P   P      C      S C   GR +++GE F+ P  S  
Sbjct: 800 SLCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHS-CLSQGREHQDGEEFEGPAGSCE 858

Query: 121 -CRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCP 159
            CRC+ G  +C       VRL     P   +V   G CCP
Sbjct: 859 WCRCQAGQVSC-------VRLQCPPLPCKLQVTERGSCCP 891



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 45/150 (30%), Positives = 56/150 (37%), Gaps = 30/150 (20%)

Query: 24  QLCP-TPCTCPWPP----PRCPL-------GVPLVLDGCGCCRVCARRLGEPCDQLHVCD 71
           Q CP TPC  P       P C L       GV    DG  C   C  + G P     +C 
Sbjct: 346 QECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCT-ACVCQDGVPKCGAVLCP 404

Query: 72  ASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSI--RCRCEDGGFT 129
            +    CQ    P G  A C   +   SC  + ++Y  G+ F    S    C C+DG  T
Sbjct: 405 PAP---CQHPTQPPG--ACCPSCD---SCTYHSQVYANGQNFTDADSPCHACHCQDGTVT 456

Query: 130 CVPLCSEDVRLPSWDCPHPRRVEVLGKCCP 159
           C       V  P   C  P+     G+CCP
Sbjct: 457 C-----SLVDCPPTTCARPQSGP--GQCCP 479



 Score = 35.8 bits (81), Expect = 0.036
 Identities = 60/227 (26%), Positives = 73/227 (32%), Gaps = 65/227 (28%)

Query: 35   PPPRCPLGVPLVLDGCGCCRVC---------ARRLGEPCDQLHVCDASQGLV-------- 77
            PP  C L V      C  CR C           R   P      C   +G+V        
Sbjct: 875  PPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCI 934

Query: 78   ---CQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQP---HCSIRCRCEDGGFTCV 131
                QP  GP      C      S CE  GR Y  GE+FQP    C + C CE       
Sbjct: 935  SSCAQPRQGPHDCCPQC------SDCEHEGRKYEPGESFQPGADPCEV-CICE------- 980

Query: 132  PLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQFSGLVSSLPPG 191
                +    PS  C H R+   L  C P           +Q LP  GPQ           
Sbjct: 981  ---PQPEGPPSLRC-HRRQCPSLVGCPP-----------SQLLP-PGPQHC--------- 1015

Query: 192  VPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPCP 238
              CP  + A   CS    LG      +    C+ +    LC+ + CP
Sbjct: 1016 --CPTCAEALSNCSEGL-LGSELAPPDPCYTCQCQDLTWLCIHQACP 1059



 Score = 34.7 bits (78), Expect = 0.080
 Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 23/119 (19%)

Query: 104 GRLYREGETFQPHCSIRCRCEDGGFTCVPLCSEDVRLPSW-DCPHPRRVEVLGKCCPEWV 162
           GR + EG  ++P     C C+DG   C P       LP    C    +    G+      
Sbjct: 100 GRAWPEGARWEPDACTACVCQDGAAHCGP----QAHLPHCRGCSQNGQTYGNGETFSPDA 155

Query: 163 CGQGGGLGTQPLPAQGP---QFSGLVSSLPPGVPCP--------------EWSTAWGPC 204
           C     L T  +  QGP   + + L S  PPG  CP              EW+T   PC
Sbjct: 156 CTTCRCL-TGAVQCQGPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPC 213



 Score = 30.0 bits (66), Expect = 2.0
 Identities = 30/114 (26%), Positives = 39/114 (34%), Gaps = 10/114 (8%)

Query: 48   DGCGCCRVCARRLGEPCDQLHVCDASQGLVCQPGA--GPGGRGALCLLAEDDSSCEVNGR 105
            D C  C    +  G P  + H       + C P     PG +      AE  S+C   G 
Sbjct: 972  DPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEALSNCS-EGL 1030

Query: 106  LYREGETFQPHCSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCP 159
            L    E   P     C+C+D  + C+         P   CP   R    G CCP
Sbjct: 1031 L--GSELAPPDPCYTCQCQDLTWLCIHQAC-----PELSCPLSERHTPPGSCCP 1077


>gi|56090548 insulin-like growth factor binding protein-like 1 [Homo
           sapiens]
          Length = 278

 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 33/89 (37%), Positives = 39/89 (43%), Gaps = 11/89 (12%)

Query: 22  RTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVC--- 78
           R + CP P  CP P      G+   LD CGCC  C    G  C          GLVC   
Sbjct: 42  RPEGCPAPAPCPAP------GIS-ALDECGCCARCLGAEGASCGGRAGGRCGPGLVCASQ 94

Query: 79  QPGAGPGGRGALCLLAEDDSSCEVNGRLY 107
             GA P G G LC+ A+  + C  +GR Y
Sbjct: 95  AAGAAPEGTG-LCVCAQRGTVCGSDGRSY 122


>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
          Length = 1044

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 56/218 (25%), Positives = 71/218 (32%), Gaps = 32/218 (14%)

Query: 30  CTCP--WPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVCQPGAGPGGR 87
           CTC   W    C    P+   G GC   C  + G  C  +     + G  C PG      
Sbjct: 379 CTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSI-----TGGCTCAPGF----M 429

Query: 88  GALCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCVPLCSEDVRLPSW---D 144
           G +C +     SC           T+ P+CS  C C +GG TC P+         W   D
Sbjct: 430 GEVCAV-----SCAAG--------TYGPNCSSICSCNNGG-TCSPVDGSCTCKEGWQGLD 475

Query: 145 CPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQFSGLVSSLPPGVPCPEWSTAWGPC 204
           C  P      G  C E  C    G    P+        G +      +PCP+  T    C
Sbjct: 476 CTLPCPSGTWGLNCNE-SCTCANGAACSPIDGSCSCTPGWLGDTCE-LPCPD-GTFGLNC 532

Query: 205 STTCGLGMATRVSN-QNRFCRLETQRRLCLSRPCPPSR 241
           S  C    A          C L     +     CPP R
Sbjct: 533 SEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGR 570



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 48/172 (27%), Positives = 63/172 (36%), Gaps = 32/172 (18%)

Query: 26  CPTPCTCP----WPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLH---VCDAS-QGLV 77
           C +P TC     W  P C  G      G  C   C  + G  C+ +    VC A  +G  
Sbjct: 112 CVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWR 171

Query: 78  CQPGAGPGGRGALCLL---AEDDSSCEVNGR----------LYREGETFQP-----HCSI 119
           C+    PG  G  C L       +SC+              +Y E E   P     HC +
Sbjct: 172 CEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCE-ELCPPGSHGAHCEL 230

Query: 120 RCRCEDGGFTCVPLCSEDVRLPSWD---CPHPRRVEVLGK-CCPEWVCGQGG 167
           RC C++GG TC  +  E    P W    C  P      G+ C  +  C  GG
Sbjct: 231 RCPCQNGG-TCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGG 281



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 44/146 (30%), Positives = 53/146 (36%), Gaps = 32/146 (21%)

Query: 30  CTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVCQPGAGPGGRGA 89
           CT  W    C L  P    G  C   C       C     CD   G  C      G  G 
Sbjct: 510 CTPGWLGDTCELPCPDGTFGLNCSEHC------DCSHADGCDPVTGHCC---CLAGWTGI 560

Query: 90  LCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPR 149
            C     DS+C   GR       + P+CS+ C CE+GG +C P   ED    S +C    
Sbjct: 561 RC-----DSTCPP-GR-------WGPNCSVSCSCENGG-SCSP---ED---GSCECAPGF 600

Query: 150 RVEVLGKCCPEWVCGQGGGLGTQPLP 175
           R  +  + CP    G G     QP P
Sbjct: 601 RGPLCQRICPPGFYGHG---CAQPCP 623



 Score = 32.0 bits (71), Expect = 0.52
 Identities = 24/86 (27%), Positives = 28/86 (32%), Gaps = 8/86 (9%)

Query: 30  CTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLH-VCDASQGLV-------CQPG 81
           CT  W    C    P    G  C RVC  + G  CD +   C    G         C PG
Sbjct: 727 CTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPG 786

Query: 82  AGPGGRGALCLLAEDDSSCEVNGRLY 107
               G   LC    + +   V G  Y
Sbjct: 787 TFGYGCQQLCECMNNSTCDHVTGTCY 812



 Score = 30.4 bits (67), Expect = 1.5
 Identities = 24/91 (26%), Positives = 36/91 (39%), Gaps = 10/91 (10%)

Query: 109 EGETFQPHCSIRCRCEDGGFTCVPL---CSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQ 165
           + + + PHCS RC+C++G   C P+   C        W C         GK C +  C  
Sbjct: 134 DSDHWGPHCSNRCQCQNGAL-CNPITGACVCAAGFRGWRCEELCAPGTHGKGC-QLPCQC 191

Query: 166 GGGLGTQPLPAQ---GPQFSGLVSS--LPPG 191
             G    P   +    P ++G+      PPG
Sbjct: 192 RHGASCDPRAGECLCAPGYTGVYCEELCPPG 222



 Score = 30.4 bits (67), Expect = 1.5
 Identities = 31/114 (27%), Positives = 40/114 (35%), Gaps = 10/114 (8%)

Query: 30  CTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQ----LHVCDASQGLVCQ---PGA 82
           C   W    C    P    G  C   C+   G  C       H      GL C    P A
Sbjct: 684 CFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAA 743

Query: 83  GPGGRGALCLLAEDDSSCE-VNGRLY-REGETFQPHCSIRCRCEDGGFTCVPLC 134
             G         ++ +SC+ ++G+   R G T Q HC  RC     G+ C  LC
Sbjct: 744 FFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQ-HCEQRCAPGTFGYGCQQLC 796


>gi|33598931 scavenger receptor class F, member 1 isoform 3
           precursor [Homo sapiens]
          Length = 569

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 55/210 (26%), Positives = 68/210 (32%), Gaps = 23/210 (10%)

Query: 16  CLLSKVRTQLCPTPCTCP--WPPPRCPLGVPLVLDGCGCCRVCAR-RLGEPCDQLHVCDA 72
           C   + R       CTCP  +   RC L  P    G  C   C R +  EPC      D 
Sbjct: 223 CECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSP----DT 278

Query: 73  SQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCVP 132
                C+PG         CL      SCE      R GE  +P      RC+ G     P
Sbjct: 279 GSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLG--P 336

Query: 133 LCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQFSGLVSSLPPG- 191
            C +        CP     E  G  CP  V G    +    + + G       +S P G 
Sbjct: 337 RCED-------PCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGF 389

Query: 192 ------VPCPEWSTAWGPCSTTCGLGMATR 215
                 VPC        P S +C  G  +R
Sbjct: 390 HGNNCSVPCECPEGLCHPVSGSCQPGSGSR 419


>gi|33598929 scavenger receptor class F, member 1 isoform 1
           precursor [Homo sapiens]
          Length = 830

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 55/210 (26%), Positives = 68/210 (32%), Gaps = 23/210 (10%)

Query: 16  CLLSKVRTQLCPTPCTCP--WPPPRCPLGVPLVLDGCGCCRVCAR-RLGEPCDQLHVCDA 72
           C   + R       CTCP  +   RC L  P    G  C   C R +  EPC      D 
Sbjct: 223 CECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSP----DT 278

Query: 73  SQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCVP 132
                C+PG         CL      SCE      R GE  +P      RC+ G     P
Sbjct: 279 GSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLG--P 336

Query: 133 LCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQFSGLVSSLPPG- 191
            C +        CP     E  G  CP  V G    +    + + G       +S P G 
Sbjct: 337 RCED-------PCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGF 389

Query: 192 ------VPCPEWSTAWGPCSTTCGLGMATR 215
                 VPC        P S +C  G  +R
Sbjct: 390 HGNNCSVPCECPEGLCHPVSGSCQPGSGSR 419


>gi|24308541 HtrA serine peptidase 4 precursor [Homo sapiens]
          Length = 476

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 28/66 (42%), Positives = 31/66 (46%), Gaps = 11/66 (16%)

Query: 20 KVRTQ-LCPTPCT---CPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQG 75
          K+ TQ  CP  C    CP   P C LG   V D C CCRVC      P  +  VC  +QG
Sbjct: 33 KLHTQPSCPAVCQPTRCP-ALPTCALGTTPVFDLCRCCRVC------PAAEREVCGGAQG 85

Query: 76 LVCQPG 81
            C PG
Sbjct: 86 QPCAPG 91


>gi|22129776 HtrA serine peptidase 3 [Homo sapiens]
          Length = 453

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 33/100 (33%), Positives = 38/100 (38%), Gaps = 11/100 (11%)

Query: 9   LLAFSLLCLLSKVRTQLCPTPCTCP-WPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQL 67
           L A + L L  +     CP  C     P PRCP G   V D C CC VCA   GEPC   
Sbjct: 8   LAALAALALAREPPAAPCPARCDVSRCPSPRCPGGY--VPDLCNCCLVCAASEGEPCGGP 65

Query: 68  HVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLY 107
                 + L C  G        LC      + C  +G  Y
Sbjct: 66  LDSPCGESLECVRG--------LCRCRWSHAVCGTDGHTY 97


>gi|5901946 endothelial cell-specific molecule 1 isoform a precursor
           [Homo sapiens]
          Length = 184

 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 35/107 (32%), Positives = 39/107 (36%), Gaps = 20/107 (18%)

Query: 26  CPTPCTCPW--PPPRCPLGVPLVLDGCGCCRVCARRLGEPC----DQLHVCDASQGLVCQ 79
           CP  C        PRC      VLD CGCCRVCA   GE C      +       GL CQ
Sbjct: 28  CPQHCDSSECKSSPRCKR---TVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQ 84

Query: 80  PGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDG 126
           P  G    G    + +D   C           TF   C   C C+ G
Sbjct: 85  PSNGEDPFGEEFGICKD---CPYG--------TFGMDCRETCNCQSG 120


>gi|208022668 endothelial cell-specific molecule 1 isoform b
           precursor [Homo sapiens]
          Length = 134

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 30/90 (33%), Positives = 36/90 (40%), Gaps = 9/90 (10%)

Query: 26  CPTPCTCPW--PPPRCPLGVPLVLDGCGCCRVCARRLGEPC----DQLHVCDASQGLVCQ 79
           CP  C        PRC      VLD CGCCRVCA   GE C      +       GL CQ
Sbjct: 28  CPQHCDSSECKSSPRCKR---TVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQ 84

Query: 80  PGAGPGGRGALCLLAEDDSSCEVNGRLYRE 109
           P  G    G    + ++      +G + RE
Sbjct: 85  PSNGEDPFGEEFGICKEHDMASGDGNIVRE 114


>gi|55925576 insulin-like growth factor binding protein 2, 36kDa
           [Homo sapiens]
          Length = 328

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 34/95 (35%), Positives = 38/95 (40%), Gaps = 23/95 (24%)

Query: 26  CPTPCT------CPWPPPRCPLGVPLVLDG-------------CGCCRVCARRLGEPCDQ 66
           CP PCT      C  PP   P  V  V  G             CGCC VCAR  GE C  
Sbjct: 45  CP-PCTPERLAACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACG- 102

Query: 67  LHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCE 101
           ++     QGL C P   PG    L  L   + +CE
Sbjct: 103 VYTPRCGQGLRCYP--HPGSELPLQALVMGEGTCE 135


>gi|40317628 thrombospondin 2 precursor [Homo sapiens]
          Length = 1172

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 50/192 (26%), Positives = 64/192 (33%), Gaps = 54/192 (28%)

Query: 98  SSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKC 157
           S+C  +GR + E ET+       C C+     C       +  P   C  P  VE  G+C
Sbjct: 318 SACWQDGRFFAENETWVVDSCTTCTCKKFKTIC-----HQITCPPATCASPSFVE--GEC 370

Query: 158 CP----------------EWV-CGQGGGLGTQPLPAQ---------GPQFSGLVSSLPPG 191
           CP                EW  C    G GTQ              GP       SL   
Sbjct: 371 CPSCLHSVDGEEGWSPWAEWTQCSVTCGSGTQQRGRSCDVTSNTCLGPSIQTRACSLSK- 429

Query: 192 VPCPE-------WS--TAWGPCSTTCGLGMATRVSNQN--------RFCR-LETQRRLCL 233
             C         WS  + W  CS TCG+G  TR+   N        + C+    + + C 
Sbjct: 430 --CDTRIRQDGGWSHWSPWSSCSVTCGVGNITRIRLCNSPVPQMGGKNCKGSGRETKACQ 487

Query: 234 SRPCPPSRGRSP 245
             PCP     SP
Sbjct: 488 GAPCPIDGRWSP 499


>gi|40353769 chordin-like 2 [Homo sapiens]
          Length = 451

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 47/170 (27%), Positives = 60/170 (35%), Gaps = 54/170 (31%)

Query: 31  TCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQ------LH-------VCDASQGLV 77
           TCP   P CP  +PL      CC+ C     E  D+      LH        C +  G  
Sbjct: 154 TCP--EPGCPAPLPL---PDSCCQACKDEASEQSDEEDSVQSLHGVRHPQDPCSSDAGRK 208

Query: 78  CQPGA-----------------GPGGRGA----LCLLAEDDSSCEVNGRLYREGE----- 111
             PG                   P G G+    + L  +   +C   G+ Y  GE     
Sbjct: 209 RGPGTPAPTGLSAPLSFIPRHFRPKGAGSTTVKIVLKEKHKKACVHGGKTYSHGEVWHPA 268

Query: 112 --TFQPHCSIRCRCEDGGFTCVPLCSEDVRLPS-WDCPHPRRVEVLGKCC 158
              F P   I C CEDG   C     + V  P+ + C HP +  V GKCC
Sbjct: 269 FRAFGPLPCILCTCEDGRQDC-----QRVTCPTEYPCRHPEK--VAGKCC 311



 Score = 30.4 bits (67), Expect = 1.5
 Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 18/70 (25%)

Query: 99  SCEVNGRLYREGETFQ---------PHCSIRCRCEDGGFTC-VPLCSEDVRLPSWDCPHP 148
           SC+ NG +Y+ GE F          P+  + C C +G   C +  C      P   CP P
Sbjct: 110 SCQHNGTMYQHGEIFSAHELFPSRLPNQCVLCSCTEGQIYCGLTTC------PEPGCPAP 163

Query: 149 RRVEVLGKCC 158
             + +   CC
Sbjct: 164 --LPLPDSCC 171


>gi|4504619 insulin-like growth factor binding protein 7 [Homo
           sapiens]
          Length = 282

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 38/117 (32%), Positives = 47/117 (40%), Gaps = 18/117 (15%)

Query: 10  LAFSLLCLLSKVRTQLCPT--PCTCP-WPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQ 66
           L   LL L S   +  C    P +CP  PP  C LG     D CGCC +CAR  GEPC  
Sbjct: 16  LLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGE--TRDACGCCPMCARGEGEPCGG 73

Query: 67  LHVCD--ASQGLVC---------QPGAGPGGRG--ALCLLAEDDSSCEVNGRLYREG 110
                   + G+ C         + GA  GG G   +C+       C  +G  Y  G
Sbjct: 74  GGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSG 130


>gi|134031945 SCO-spondin [Homo sapiens]
          Length = 5147

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 57/216 (26%), Positives = 74/216 (34%), Gaps = 39/216 (18%)

Query: 48   DGCGCCRVCARRLGEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLY 107
            +G  C R+C  + G   +    C  + G  C PG       A CL       C+++G+LY
Sbjct: 2901 EGGPCPRLCLTQ-GPGIECTGFC--APGCTCPPGLFL--HNASCL-PRSQCPCQLHGQLY 2954

Query: 108  REGETFQPHCSIRCRCEDGGFTCVPLCSEDVRLPSWDCP-----HPRRVEVLGKCCPEWV 162
              G   +      C C  G   C           S  CP      P  +  L  C     
Sbjct: 2955 ASGAMARLDSCNNCTCVSGKMACT----------SERCPVACGWSPWTLWSLCSCSCNVG 3004

Query: 163  CGQGGGLGTQPLPA------QGPQFSGLVSSLPPGVPCP----EWSTAWGPCSTTCGLGM 212
              +    GT P  A      QGP       SL P   CP    EW   W PCS  CG G 
Sbjct: 3005 IRRRFRAGTAPPAAFGGAECQGPTMEAEFCSLRP---CPGPGGEWGP-WSPCSVPCGGGY 3060

Query: 213  ATRVSNQNRFCRLETQRRLCLSRPCP-PSRGRSPQN 247
              R    +R      +   C  +PC  P  G  P++
Sbjct: 3061 RNRTRGSSRSL---MEFSTCGLQPCAGPVPGMCPRD 3093



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 62/244 (25%), Positives = 82/244 (33%), Gaps = 93/244 (38%)

Query: 16   CLLSKVRTQLC-PTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQ 74
            C   + + +LC P PC        CP G+ +V     C   C RR           D  +
Sbjct: 4043 CAGERHQARLCNPMPCEAG-----CPAGMEVVT----CANRCPRRCS---------DLQE 4084

Query: 75   GLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRC------EDGGF 128
            G+VCQ                DD  C+                   CRC      +DGG 
Sbjct: 4085 GIVCQ----------------DDQVCQKG-----------------CRCPKGSLEQDGG- 4110

Query: 129  TCVPL----CSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQFSGL 184
             CVP+    C+ D +  SW  P  +  +    C                   Q  Q S  
Sbjct: 4111 -CVPIGHCDCT-DAQGHSW-APGSQHQDACNNCS-----------------CQAGQLSCT 4150

Query: 185  VSSLPPGVPCPEWS--TAWGPCSTTCG-LGMATRVSNQNR-----FCRLE-TQRRLCLSR 235
                PP   C  WS  +AW PCS +CG  G  +R  +         CR E +Q + C   
Sbjct: 4151 AQPCPPPTHCA-WSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQSQSQPCPQP 4209

Query: 236  PCPP 239
             CPP
Sbjct: 4210 SCPP 4213



 Score = 41.2 bits (95), Expect = 9e-04
 Identities = 53/195 (27%), Positives = 64/195 (32%), Gaps = 44/195 (22%)

Query: 61   GEPCDQLHVC-DASQ----GLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQP 115
            G  CDQ   C D S     G  C P   P  RG  C+  E                    
Sbjct: 1581 GWRCDQEEDCADGSDERGCGGPCAPHHAPCARGPHCVSPEQ------------------- 1621

Query: 116  HCSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLP 175
             C    +C DG       C     LP+   P+       G  CPE+ C  G  +G Q + 
Sbjct: 1622 LCDGVRQCPDGSDEGPDACGG---LPALGGPNRT-----GLPCPEYTCPNGTCIGFQLVC 1673

Query: 176  AQGPQFS--GLVSSLPPGVPCPEWS--TAWGPCSTTC---GLGMATRVSNQNRFCRL--- 225
               P     G V   P    C  W   + WGPCS TC   G G + R S           
Sbjct: 1674 DGQPDCGRPGQVGPSPEEQGCGAWGPWSPWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCP 1733

Query: 226  --ETQRRLCLSRPCP 238
              E Q + C +  CP
Sbjct: 1734 GPEHQSQACFTAACP 1748



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 56/188 (29%), Positives = 73/188 (38%), Gaps = 51/188 (27%)

Query: 61   GEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQP-HCSI 119
            G+PC +    D S G VCQPG+         +  +    C + G+L ++G    P HC  
Sbjct: 3539 GQPCPR-SCQDLSPGSVCQPGS---------VGCQPTCGCPL-GQLSQDGLCVPPAHC-- 3585

Query: 120  RCRCEDG--GFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQ 177
            RC+ + G  G       S   R  SW+   P   EV+   C    C   G L  Q +P  
Sbjct: 3586 RCQYQPGAMGIPENQSRSAGSRFSSWESLEPG--EVVTGPCDNCTC-VAGILQCQEVP-- 3640

Query: 178  GPQFSGLVSSLPPGVPCPEWSTAWGP---CSTTCGLGMATRVSNQNRFCRLETQRRLCLS 234
                        PGV    WS +WGP   CS +CG G   R              R C  
Sbjct: 3641 --------DCPDPGV----WS-SWGPWEDCSVSCGGGEQLR-------------SRRCAR 3674

Query: 235  RPCP-PSR 241
             PCP P+R
Sbjct: 3675 PPCPGPAR 3682



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 41/150 (27%), Positives = 51/150 (34%), Gaps = 52/150 (34%)

Query: 120  RCRCEDGGFTCVPL-CSEDVRLPSW----DCPHPRRVEVLGKCCPEWVCGQGGGLGTQPL 174
            RC C   G  C    C+       W    DCP                CG G  + T+  
Sbjct: 4235 RCSCTPEGVICEDTECAVPEAWTLWSSWSDCPVS--------------CGGGNQVRTRAC 4280

Query: 175  PAQGPQFSGLVSSLPPGV---------PCPEWSTA-----WGPCSTTCGLGMATRVSN-- 218
             A  P         PP +         PCP    A     WGPCS +CG G+A+R  +  
Sbjct: 4281 RAAAPHHRS-----PPCLGPDTQTRQQPCPGLLEACSWGPWGPCSRSCGPGLASRSGSCP 4335

Query: 219  ----------QNRFCRLETQRRLCLSRPCP 238
                       + F  L+TQ   C S PCP
Sbjct: 4336 CLMAKADPTCNSTFLHLDTQG--CYSGPCP 4363



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 66/264 (25%), Positives = 84/264 (31%), Gaps = 82/264 (31%)

Query: 15   LCLLSKVRTQLCPTPCTC----------PWPPPRCPL--GVPL------VLDGCGCCRVC 56
            LC     + +LCP P  C          PW P + P   G  L       L G GC    
Sbjct: 4595 LCTAPLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPW 4654

Query: 57   ARRL--GEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQ 114
            A+    G PC +    D    L C                +   SC     L+   +  Q
Sbjct: 4655 AQESCNGGPCPECEAQDTVFTLDC--------------ANQCPHSC---ADLWDRVQCLQ 4697

Query: 115  PHCSIRCRCEDGGFT----CVPLCSEDVRLP----SWDCPHPRRVEVLGKCCPEWVC-GQ 165
              C   CRC  G       CVP+ S    LP    SW+    + V++    C    C  +
Sbjct: 4698 GPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQL---DCQNCTCVNE 4754

Query: 166  GGGLGTQPLPAQGPQFSGLVSSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNRFC-- 223
                  Q  P  GP                 WS AW  CS  CG G   R    +R C  
Sbjct: 4755 SLVCPHQECPVLGP-----------------WS-AWSSCSAPCGGGTMER----HRTCEG 4792

Query: 224  ---------RLETQRRLCLSRPCP 238
                     +   QR+ C  +PCP
Sbjct: 4793 GPGVAPCQAQDTEQRQECNLQPCP 4816



 Score = 35.8 bits (81), Expect = 0.036
 Identities = 54/201 (26%), Positives = 71/201 (35%), Gaps = 59/201 (29%)

Query: 31   TCPWPPPR-----CPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLV----CQPG 81
            +C  PPP+     CP G       CG          +PC     C+  +  V    CQ G
Sbjct: 2581 SCVDPPPKNGGAPCP-GASQERAPCGL---------QPCSGGTDCELGRVYVSADLCQKG 2630

Query: 82   AGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDG----GFTCVPLCSED 137
              P    + CL  + + SC               HC   CRC  G       C+PL SE 
Sbjct: 2631 LVPPCPPS-CLDPKANRSCS-------------GHCVEGCRCPPGLLLHDTRCLPL-SEC 2675

Query: 138  VRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQFSGLVSSLPPGVPCP-E 196
              L   +   P    +LG C  + VC +G  L                   P G P P  
Sbjct: 2676 PCLVGEELKWPGVSFLLGNCS-QCVCEKGELL-----------------CQPGGCPLPCG 2717

Query: 197  WS--TAWGPCSTTCGLGMATR 215
            WS  ++W PC  +CG G+  R
Sbjct: 2718 WSAWSSWAPCDRSCGSGVRAR 2738



 Score = 33.9 bits (76), Expect = 0.14
 Identities = 30/82 (36%), Positives = 33/82 (40%), Gaps = 10/82 (12%)

Query: 114  QPHCSIRCR----CEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGL 169
            Q  CS++C      E  G TC P C E    P W C     VE  G  CPE     GG  
Sbjct: 1268 QELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVE--GCFCPEGTLLHGGAC 1325

Query: 170  GTQPLPAQGPQFSGLVSSLPPG 191
                 PA  P   G  +S PPG
Sbjct: 1326 LE---PASCPCEWGR-NSFPPG 1343



 Score = 32.3 bits (72), Expect = 0.40
 Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 12/56 (21%)

Query: 197  WSTAWGPCSTTCGLGMATRVSNQ----------NRFCRLETQRRLCLSRPCPPSRG 242
            WS  WGPCS +CG G+ TR  ++           + CR   Q   C S  CP + G
Sbjct: 3817 WSP-WGPCSRSCG-GLGTRTRSRQCVLTMPTLSGQGCRGPRQDLECPSPDCPGAEG 3870



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 35/147 (23%), Positives = 48/147 (32%), Gaps = 22/147 (14%)

Query: 27   PTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRL-----GEPCDQLHVCDASQGLVCQPG 81
            P  C C W     P G  L  D CG C     +      G  C++L    A    +CQ  
Sbjct: 1328 PASCPCEWGRNSFPPGSVLQKD-CGNCTCQEGQWHCGGDGGHCEELVPACAEGEALCQEN 1386

Query: 82   AGPGGRGALCLLAED------DSSCEVNGRLYREGETFQPHC---SIRCRCEDGGFTCVP 132
                  G LC   +D      +  C   G    +      HC   ++ C  +D       
Sbjct: 1387 GHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQDD------ 1440

Query: 133  LCSEDVRLPSWDCPHPRRVEVLGKCCP 159
             C +    PS+ CP        G+C P
Sbjct: 1441 -CGDGTDEPSYPCPQGLLACADGRCLP 1466



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 33/112 (29%), Positives = 40/112 (35%), Gaps = 25/112 (22%)

Query: 117  CSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPA 176
            C   C C  G      L   +V +P+ DCP          C  E      G    +P   
Sbjct: 3119 CHPGCHCPSG-----MLLLNNVCVPTQDCP----------CAHEGHLYPPGSTVVRPCE- 3162

Query: 177  QGPQFSGLV---SSLPPGVPCPEWS--TAWGPCSTTCGLGMATRVSNQNRFC 223
                 SGL+   SS P     P WS  T W  CS +CG     R    +RFC
Sbjct: 3163 NCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPARCHR----HRFC 3210



 Score = 30.4 bits (67), Expect = 1.5
 Identities = 53/218 (24%), Positives = 67/218 (30%), Gaps = 58/218 (26%)

Query: 38   RCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVCQPGAG-PGGRGALCLLAED 96
            +C L +P  L G GC R   + L  P      C  ++G   +P  G PGG G     +  
Sbjct: 3838 QCVLTMP-TLSGQGC-RGPRQDLECPSPD---CPGAEGSTVEPVTGLPGGWGPWSSWSPC 3892

Query: 97   DSSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGK 156
              SC    R         P    R R       C+  C+    L    C  P   E+   
Sbjct: 3893 SRSCTDPAR---------PAWRSRTRL------CLANCTMGDPLQERPCNLPSCTEL--P 3935

Query: 157  CCPEWVCGQGGGLGTQPLPAQGPQFSGLVSSLPPGVPCPEWSTAWGPCSTTCGLGMATRV 216
             CP   CG G    T   P                         W PCS +CG+G   R+
Sbjct: 3936 VCPGPGCGAGNCSWTSWAP-------------------------WEPCSRSCGVGQQRRL 3970

Query: 217  SNQN----------RFCRLETQRRLCLSRPCPPSRGRS 244
                                 +RR C  R CP   G S
Sbjct: 3971 RAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWS 4008



 Score = 28.9 bits (63), Expect = 4.4
 Identities = 16/46 (34%), Positives = 21/46 (45%), Gaps = 15/46 (32%)

Query: 200  AWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPCPPSRGRSP 245
            AWGPCS +CG G  +R             +R C+    PP  G +P
Sbjct: 2563 AWGPCSVSCGGGHQSR-------------QRSCVDP--PPKNGGAP 2593



 Score = 28.5 bits (62), Expect = 5.8
 Identities = 46/181 (25%), Positives = 63/181 (34%), Gaps = 35/181 (19%)

Query: 84   PGGRGALC---------LLAEDDSSCEVNGRLYREGETFQPHCSIRCRC-EDGGFTCVPL 133
            P GRG  C            E    CE  G+++R GE +       C+C  +    C P 
Sbjct: 1942 PSGRGRQCRGIHRKARRCQTEPCEGCEHQGQVHRVGERWHGGPCRVCQCLHNLTAHCSPY 2001

Query: 134  CSEDVRLPSWDCPHP-RRVEVLGK-CCPEWVCGQGGGLGTQPLPAQGP------QFSGLV 185
            C      P   CP     VE  G+ CC   + G+   +     PA  P      +F    
Sbjct: 2002 C------PLGSCPQGWVLVEGTGESCCHCALPGENQTVQPMATPAAAPAPSPQIRFPLAT 2055

Query: 186  SSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPCPPSRGRSP 245
              LPP         +  PC +  GL      S      +LE   +  L     P++G SP
Sbjct: 2056 YILPP---------SGDPCYSPLGLAGLAEGSLHASSQQLEHPTQAALLG--APTQGPSP 2104

Query: 246  Q 246
            Q
Sbjct: 2105 Q 2105



 Score = 27.7 bits (60), Expect = 9.8
 Identities = 18/48 (37%), Positives = 20/48 (41%), Gaps = 9/48 (18%)

Query: 197  WSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPCPPSRGRS 244
            WS  W  CS +CGLG+         F R E  R       CP  R RS
Sbjct: 2506 WSV-WSSCSRSCGLGLT--------FQRQELLRPPLPGGSCPRDRFRS 2544


>gi|33624896 ADAM metallopeptidase with thrombospondin type 1 motif, 9
            preproprotein [Homo sapiens]
          Length = 1935

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 56/210 (26%), Positives = 77/210 (36%), Gaps = 41/210 (19%)

Query: 63   PCDQLHVCD-ASQGLVCQPGAGPGGRGALCLLAEDD----SSCEVNGRLYREGETFQPHC 117
            PC Q    D +S  + C  G G   R  +C+   D     S C+ +     + +     C
Sbjct: 1238 PCGQWKALDWSSCSVTC--GQGRATRQVMCVNYSDHVIDRSECDQDYIPETDQDCSMSPC 1295

Query: 118  SIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLG----KCCPEWVCGQ--GGGLGT 171
              R    D G    P  +ED R  S     P R  VLG    +  P   C     GG   
Sbjct: 1296 PQRT--PDSGLAQHPFQNEDYRPRS---ASPSRTHVLGGNQWRTGPWGACSSTCAGGSQR 1350

Query: 172  QPLPAQ---GPQFSGLVSSLPPGV-------PCPEWSTA-WGPCSTTCGLGMATRV---- 216
            + +  Q   G   +  V  + P         PCP+W+   WG C+  CG G+ TR+    
Sbjct: 1351 RVVVCQDENGYTANDCVERIKPDEQRACESGPCPQWAYGNWGECTKLCGGGIRTRLVVCQ 1410

Query: 217  -SNQNRFCRLETQ-------RRLCLSRPCP 238
             SN  RF  L  +       R  C +  CP
Sbjct: 1411 RSNGERFPDLSCEILDKPPDREQCNTHACP 1440



 Score = 35.8 bits (81), Expect = 0.036
 Identities = 36/142 (25%), Positives = 52/142 (36%), Gaps = 32/142 (22%)

Query: 102  VNGRLYREGETFQPHCSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKC---- 157
            + G  +R G    P  +    C  G    V +C ++    + DC    + +    C    
Sbjct: 1327 LGGNQWRTG----PWGACSSTCAGGSQRRVVVCQDENGYTANDCVERIKPDEQRACESGP 1382

Query: 158  CPEWVCGQ--------GGGLGTQPLPAQ---GPQFSGLVSSLPPGVP---------CPE- 196
            CP+W  G         GGG+ T+ +  Q   G +F  L   +    P         CP  
Sbjct: 1383 CPQWAYGNWGECTKLCGGGIRTRLVVCQRSNGERFPDLSCEILDKPPDREQCNTHACPHD 1442

Query: 197  --WSTA-WGPCSTTCGLGMATR 215
              WST  W  CS +CG G   R
Sbjct: 1443 AAWSTGPWSSCSVSCGRGHKQR 1464



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 12/26 (46%), Positives = 15/26 (57%), Gaps = 1/26 (3%)

Query: 191  GVPCPEWST-AWGPCSTTCGLGMATR 215
            G  CP+W   AW  CS +CG G+  R
Sbjct: 1495 GGRCPKWKAGAWSQCSVSCGRGVQQR 1520



 Score = 28.5 bits (62), Expect = 5.8
 Identities = 11/23 (47%), Positives = 11/23 (47%), Gaps = 1/23 (4%)

Query: 194  CPEWSTA-WGPCSTTCGLGMATR 215
            C  W    WG CS TCG G   R
Sbjct: 1108 CASWQAGPWGQCSVTCGQGYQLR 1130


>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
           sapiens]
          Length = 1037

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 43/139 (30%), Positives = 51/139 (36%), Gaps = 30/139 (21%)

Query: 30  CTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVCQPGAGPGGRGA 89
           CT  W    C L  P    G GC   C       CD    CD   G  CQ  A  G  GA
Sbjct: 511 CTPGWHGAHCQLPCPKGQFGEGCASRC------DCDHSDGCDPVHGR-CQCQA--GWMGA 561

Query: 90  LCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCVP-----LCSEDVRLPSWD 144
            C L+  +    VN             CS  C C++GG TC+P     +C+   R PS  
Sbjct: 562 RCHLSCPEGLWGVN-------------CSNTCTCKNGG-TCLPENGNCVCAPGFRGPS-- 605

Query: 145 CPHPRRVEVLGKCCPEWVC 163
           C    +    GK C    C
Sbjct: 606 CQRSCQPGRYGKRCVPCKC 624



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 56/212 (26%), Positives = 68/212 (32%), Gaps = 62/212 (29%)

Query: 26  CPTPCTCP-------------------WPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQ 66
           C  PCTC                    W    C    P    G GC   C       C  
Sbjct: 359 CQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCL------CLH 412

Query: 67  LHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDG 126
             VC A+ GL CQ    PG  G  C      S C          +T+  +CS RC CE+ 
Sbjct: 413 GGVCQATSGL-CQ--CAPGYTGPHCA-----SLCPP--------DTYGVNCSARCSCEN- 455

Query: 127 GFTCVPLCSEDVRLPSW---DCPHPRRVEVLG-------KCCPEWVCGQGGGLGTQPLPA 176
              C P+  E V    W   +C  P      G       +C  E VC    G  T     
Sbjct: 456 AIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCT--- 512

Query: 177 QGPQFSGLVSSLPPGVPCPEWSTAWGPCSTTC 208
             P + G    L    PCP+     G C++ C
Sbjct: 513 --PGWHGAHCQL----PCPKGQFGEG-CASRC 537



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 61/246 (24%), Positives = 80/246 (32%), Gaps = 46/246 (18%)

Query: 30  CTCP--WPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQL----------------HVC- 70
           C+CP  W    C L  P    G  C + C    G  CD+                   C 
Sbjct: 248 CSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECP 307

Query: 71  ------DASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRCE 124
                 D ++   C P A        CL     +      RL  +G  +   C   C C+
Sbjct: 308 VGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDG-FYGLSCQAPCTCD 366

Query: 125 -DGGFTCVPLCSEDVRLPSW---DCPHPRRVEVLGKCCPEWVCGQGGGL--GTQPLPAQG 178
            +   +C P+  E   LP W    C      +  G  C E      GG+   T  L    
Sbjct: 367 REHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCA 426

Query: 179 PQFSG--LVSSLPP---GVPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCL 233
           P ++G    S  PP   GV C         CS  C   +A    +    C+   QR  C 
Sbjct: 427 PGYTGPHCASLCPPDTYGVNCS------ARCS--CENAIACSPIDGECVCKEGWQRGNC- 477

Query: 234 SRPCPP 239
           S PCPP
Sbjct: 478 SVPCPP 483



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 31/111 (27%), Positives = 39/111 (35%), Gaps = 11/111 (9%)

Query: 26  CPTPCTCPWPPPRCPLGVPLVLDGC----GCCRVCARRLGEPCDQLHVCDASQGLVCQPG 81
           C  PCT  +  P C          C    G C   A R G  CD +     + G  C P 
Sbjct: 174 CLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCD-VSCSQGTSGFFC-PS 231

Query: 82  AGPGGRGALCLLAEDDSSCEVN--GRLYREG--ETFQ-PHCSIRCRCEDGG 127
                 G +    +   SC     G +      E F  P+CS  CRC +GG
Sbjct: 232 THSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGG 282



 Score = 29.6 bits (65), Expect = 2.6
 Identities = 18/54 (33%), Positives = 20/54 (37%), Gaps = 7/54 (12%)

Query: 30  CTCP--WPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVCQPG 81
           C CP  W    C  G PL   G  C + C    GE C        +   VC PG
Sbjct: 680 CICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCH-----PETGACVCPPG 728



 Score = 28.1 bits (61), Expect = 7.5
 Identities = 28/115 (24%), Positives = 37/115 (32%), Gaps = 9/115 (7%)

Query: 25  LCPTPCTCP--WPPPRCPLGVPLVLDGCGCCRVCARRLGEPCD-QLHVCDASQGLV---C 78
           + P  C C   W    C       + G  C + C+      CD +  VC    GL    C
Sbjct: 115 VAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNC 174

Query: 79  QPGAGPGGRGALCLLAED--DSSCEVN-GRLYREGETFQPHCSIRCRCEDGGFTC 130
                PG  G  C        + C+   G  +   E   P C + C     GF C
Sbjct: 175 LQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFC 229


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 27/82 (32%), Positives = 34/82 (41%), Gaps = 7/82 (8%)

Query: 49   GCGCCRVCARRLGEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYR 108
            G  C R C   L   C   H      G VC PG    G G    +AE+D  C  N   Y+
Sbjct: 1471 GAECLRSC-HTLDVGCFSTHCVS---GCVCPPGLVSDGSGGC--IAEEDCPCVHNEATYK 1524

Query: 109  EGETFQPHCSIRCRCEDGGFTC 130
             GET +  C+  C C +  + C
Sbjct: 1525 PGETIRVDCN-TCTCRNRRWEC 1545



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 44/167 (26%), Positives = 59/167 (35%), Gaps = 30/167 (17%)

Query: 13   SLLCLLSKVRTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPC--DQLHVC 70
            S +C    V  Q  P PC     PP C        +  G   V   R   PC  + + VC
Sbjct: 5771 SCVCDEGSVSVQCKPLPCDAQGQPPPC--------NRPGFVTVTRPRAENPCCPETVCVC 5822

Query: 71   DAS---QGL-VCQPGAGPGGRGALCLLAEDD---------SSCEVNGRLYREGETFQPHC 117
            + +   Q L VC P     G+ ++C   E D           C  NG  Y  G TF    
Sbjct: 5823 NTTTCPQSLPVCPP-----GQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGATFPGAL 5877

Query: 118  SIR-CRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVE-VLGKCCPEWV 162
                C C  G      +  ++    +  CP     + V G+CC E V
Sbjct: 5878 PCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECV 5924



 Score = 34.7 bits (78), Expect = 0.080
 Identities = 32/122 (26%), Positives = 39/122 (31%), Gaps = 26/122 (21%)

Query: 22   RTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVCQPG 81
            R   CP  C     P  CPL +     G  C   C+        + H  D   G  C PG
Sbjct: 973  RNWRCPELC-----PRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVD---GCFCPPG 1024

Query: 82   AGPGGRGALCLLAED----------DSSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCV 131
                     C + +D             C   GR Y  G +F   CS  C C  G + C 
Sbjct: 1025 RS-------CTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCS-SCTCSGGLWQCQ 1076

Query: 132  PL 133
             L
Sbjct: 1077 DL 1078



 Score = 31.6 bits (70), Expect = 0.68
 Identities = 40/150 (26%), Positives = 55/150 (36%), Gaps = 25/150 (16%)

Query: 110  GETFQPHCSIRCRCEDGGFT--CVPL-CSEDVRLPSWDCPHPRRVEVL-----GKCCPEW 161
            GE +  +C   C C++G  +  C PL C    + P   C  P  V V        CCPE 
Sbjct: 5762 GERWVSNCQ-SCVCDEGSVSVQCKPLPCDAQGQPPP--CNRPGFVTVTRPRAENPCCPET 5818

Query: 162  VCGQGGGLGTQPLPAQGPQFSGLVSSLPPGVPCPEWSTAWGPCS---TTCGLG------- 211
            VC        Q LP   P    + +    G  CP +      CS   T  G+G       
Sbjct: 5819 VCVCNTTTCPQSLPVCPPGQESICTQ-EEGDCCPTFRCRPQLCSYNGTFYGVGATFPGAL 5877

Query: 212  ---MATRVSNQNRFCRLETQRRLCLSRPCP 238
               M T +S   +   ++ Q   C +  CP
Sbjct: 5878 PCHMCTCLSGDTQDPTVQCQEDACNNTTCP 5907



 Score = 28.5 bits (62), Expect = 5.8
 Identities = 19/54 (35%), Positives = 23/54 (42%), Gaps = 9/54 (16%)

Query: 147  HPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQFSGLVSSLPPGVPCPEWSTA 200
            H   + VL  CC    CG     GT P P+       L +S  P VP P  +TA
Sbjct: 2111 HDYELRVL--CCEYVPCGPSPAPGTSPQPS-------LSASTEPAVPTPTQTTA 2155


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 27/82 (32%), Positives = 34/82 (41%), Gaps = 7/82 (8%)

Query: 49  GCGCCRVCARRLGEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYR 108
           G  C R C   L   C   H      G VC PG    G G    +AE+D  C  N   Y+
Sbjct: 815 GAECLRSC-HTLDVGCFSTHCVS---GCVCPPGLVSDGSGGC--IAEEDCPCVHNEATYK 868

Query: 109 EGETFQPHCSIRCRCEDGGFTC 130
            GET +  C+  C C +  + C
Sbjct: 869 PGETIRVDCN-TCTCRNRRWEC 889



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 44/167 (26%), Positives = 59/167 (35%), Gaps = 30/167 (17%)

Query: 13   SLLCLLSKVRTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPC--DQLHVC 70
            S +C    V  Q  P PC     PP C        +  G   V   R   PC  + + VC
Sbjct: 5437 SCVCDEGSVSVQCKPLPCDAQGQPPPC--------NRPGFVTVTRPRAENPCCPETVCVC 5488

Query: 71   DAS---QGL-VCQPGAGPGGRGALCLLAEDD---------SSCEVNGRLYREGETFQPHC 117
            + +   Q L VC P     G+ ++C   E D           C  NG  Y  G TF    
Sbjct: 5489 NTTTCPQSLPVCPP-----GQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGATFPGAL 5543

Query: 118  SIR-CRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVE-VLGKCCPEWV 162
                C C  G      +  ++    +  CP     + V G+CC E V
Sbjct: 5544 PCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECV 5590



 Score = 34.7 bits (78), Expect = 0.080
 Identities = 32/122 (26%), Positives = 39/122 (31%), Gaps = 26/122 (21%)

Query: 22  RTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVCQPG 81
           R   CP  C     P  CPL +     G  C   C+        + H  D   G  C PG
Sbjct: 317 RNWRCPELC-----PRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVD---GCFCPPG 368

Query: 82  AGPGGRGALCLLAED----------DSSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCV 131
                    C + +D             C   GR Y  G +F   CS  C C  G + C 
Sbjct: 369 RS-------CTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCS-SCTCSGGLWQCQ 420

Query: 132 PL 133
            L
Sbjct: 421 DL 422



 Score = 31.6 bits (70), Expect = 0.68
 Identities = 40/150 (26%), Positives = 55/150 (36%), Gaps = 25/150 (16%)

Query: 110  GETFQPHCSIRCRCEDGGFT--CVPL-CSEDVRLPSWDCPHPRRVEVL-----GKCCPEW 161
            GE +  +C   C C++G  +  C PL C    + P   C  P  V V        CCPE 
Sbjct: 5428 GERWVSNCQ-SCVCDEGSVSVQCKPLPCDAQGQPPP--CNRPGFVTVTRPRAENPCCPET 5484

Query: 162  VCGQGGGLGTQPLPAQGPQFSGLVSSLPPGVPCPEWSTAWGPCS---TTCGLG------- 211
            VC        Q LP   P    + +    G  CP +      CS   T  G+G       
Sbjct: 5485 VCVCNTTTCPQSLPVCPPGQESICTQ-EEGDCCPTFRCRPQLCSYNGTFYGVGATFPGAL 5543

Query: 212  ---MATRVSNQNRFCRLETQRRLCLSRPCP 238
               M T +S   +   ++ Q   C +  CP
Sbjct: 5544 PCHMCTCLSGDTQDPTVQCQEDACNNTTCP 5573



 Score = 28.5 bits (62), Expect = 5.8
 Identities = 19/54 (35%), Positives = 23/54 (42%), Gaps = 9/54 (16%)

Query: 147  HPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQFSGLVSSLPPGVPCPEWSTA 200
            H   + VL  CC    CG     GT P P+       L +S  P VP P  +TA
Sbjct: 1421 HDYELRVL--CCEYVPCGPSPAPGTSPQPS-------LSASTEPAVPTPTQTTA 1465


>gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens]
          Length = 480

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 31/104 (29%), Positives = 36/104 (34%), Gaps = 31/104 (29%)

Query: 5  PKTHLLAFSLLCLLSKVRTQL------------CPTPCT---CPWPPPRCPLGVPLVLDG 49
          P+  LL   LL L +    QL            CP  C    CP  P  C  G     D 
Sbjct: 4  PRAALLPLLLLLLAAPASAQLSRAGRSAPLAAGCPDRCEPARCPPQPEHCEGG--RARDA 61

Query: 50 CGCCRVCARRLGEPCDQLHVCDASQGLVCQPGAGPGGRGALCLL 93
          CGCC VC               A +G  C    GP G G  C++
Sbjct: 62 CGCCEVCG--------------APEGAACGLQEGPCGEGLQCVV 91


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 10/75 (13%)

Query: 96  DDSSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLG 155
           ++ +C  NG++Y   + ++P     C C++G   C  +  +DV     DC  P  V   G
Sbjct: 37  EEIACTQNGQMYLNRDIWKPAPCQICVCDNGAILCDKIECQDV----LDCADP--VTPPG 90

Query: 156 KCCPEWVCGQ--GGG 168
           +CCP  VC Q  GGG
Sbjct: 91  ECCP--VCSQTPGGG 103


>gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens]
          Length = 763

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 21/114 (18%)

Query: 53  CRVCARRLGEPCDQLHVCDA---SQGLVCQPGAGPGGRGALCLLAEDDSSCEVNG-RLYR 108
           C VC+ + G+   +   CD    S  L C P          C         + NG +LYR
Sbjct: 607 CSVCSCKDGKIFCRRTACDCQNPSADLFCCPE---------CDTRVTSQCLDQNGHKLYR 657

Query: 109 EGETFQPHCSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWV 162
            G+ +   C  +CRC +G   C PL       P+  C +   +E  G+CCP  V
Sbjct: 658 SGDNWTHSCQ-QCRCLEGEVDCWPL-----TCPNLSCEYTAILE--GECCPRCV 703



 Score = 34.3 bits (77), Expect = 0.10
 Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 9/65 (13%)

Query: 97  DSSCEVNGRLYREGETF--QPHCSIRCRCEDGGFTCVPLCSEDVRLPSWDC-PHPRRVEV 153
           + +C+V+G LYR+ +++    HC   C C+ G   C       +  P  +C P    V +
Sbjct: 270 EKTCQVSGLLYRDQDSWVDGDHCR-NCTCKSGAVEC-----RRMSCPPLNCSPDSLPVHI 323

Query: 154 LGKCC 158
            G+CC
Sbjct: 324 AGQCC 328


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.142    0.516 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,570,139
Number of Sequences: 37866
Number of extensions: 900052
Number of successful extensions: 3443
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 145
Number of HSP's that attempted gapping in prelim test: 2865
Number of HSP's gapped (non-prelim): 676
length of query: 250
length of database: 18,247,518
effective HSP length: 100
effective length of query: 150
effective length of database: 14,460,918
effective search space: 2169137700
effective search space used: 2169137700
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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